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Fan Feng-Jia - - 2013
The wurtzite-derived Cu2ZnSn(S1-xSex)4 alloys are studied for the first time through combining the theoretical calculations and the experimental characterizations. Ab initio calculations predict that wurtzite-derived Cu2ZnSnS4 and Cu2ZnSnSe4 are highly miscible, and the bandgaps of the mixed-anion alloys can be linearly tuned from 1.0 to 1.5 eV through changing the ...
Li Shijun - - 2013
We describe the fabrication of a suite of [3]catenanes, obtained via the multi-component coordination-driven self-assembly and host-guest complexation of a rectangular scaffold comprising a 90° Pt-based acceptor building block with a pseudorotaxane bis(pyridinium)ethane/dibenzo[24]crown-8 linear dipyridyl ligand and three dicarboxylate donors. The doubly threaded [3]catenanes are formed from ten total molecular ...
Elam W Austin - - 2013
The native states of globular proteins have been accessed in atomic detail by X-ray crystallography and nuclear magnetic resonance spectroscopy, yet characterization of denatured proteins beyond global metrics has proven to be elusive. Denatured proteins have been observed to exhibit global geometric properties of a random coil polymer. However, this ...
Israni Ajay K AK Nephrology Division, Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN 55415-1829, USA. - - 2013
Chronic allograft dysfunction (CGD) is a common outcome in kidney transplants, but its pathogenesis is unclear. We investigated the CGD phenotype and single-nucleotide polymorphisms (SNPs) associated with CGD. This prospective study enrolled 2336 transplants from seven transplant centers in North America. CGD was defined as a >25% rise in serum ...
Zheng Weiqing - - 2013
Constant CO(x)-free H(2) production from the catalytic decomposition of ammonia could be achieved over a high surface area molybdenum carbide catalyst prepared by a temperature programmed reduction-carburization method. The fresh and used catalyst was characterized by N(2)-adsorption/desorption, powder X-ray diffraction, scanning and transmission electron microscopes and electron energy-loss spectroscopy at ...
Kubota Koji - - 2013
A borylative exo-cyclization of alkenyl halides has been reported. The reaction includes the regioselective addition of a borylcopper(I) intermediate to unactivated terminal alkenes, followed by the intramolecular substitution of the resulting alkyl-copper moiety for the halide leaving groups. This reaction provides a new method for the synthesis of alkylboronates containing ...
Cao Qing - - 2013
Single-walled carbon nanotubes have exceptional electronic properties and have been proposed as a replacement for silicon in applications such as low-cost thin-film transistors and high-performance logic devices. However, practical devices will require dense, aligned arrays of electronically pure nanotubes to optimize performance, maximize device packing density and provide sufficient drive ...
Lakshmi Jothinathan - - 2013
A batch adsorption process was applied to investigate the removal of perchlorate (ClO(4) (-)) from water by graphene. In doing so, the thermodynamic adsorption isotherm and kinetic studies were also carried out. Graphene was prepared by a facile liquid-phase exfoliation. Graphene was characterized by Raman spectroscopy, Fourier-transform infrared spectroscopy, powder ...
Marx S - - 2013
BACKGROUND: The etiology of chronic prostatitis chronic pelvic pain syndrome (CP/CPPS) is still unclear. As no pathological findings exist the diagnosis of CP/CPPS is essentially a diagnosis by exclusion and functional disorders, so-called somatoform disorders play a more important role. Osteopathy treats functional disorders of the musculoskeletal system including all ...
Krepl Miroslav - - 2013
Guanine to inosine (G→I) substitution has often been used to study various properties of nucleic acids. Inosine differs from guanine only by loss of the N2 amino group while both bases have similar electrostatic potentials. Therefore, G→I substitution appears to be optimally suited to probe structural and thermodynamics effects of ...
Sistanizad M - - 2013
WHAT IS KNOWN AND OBJECTIVE: The causes of drug-induced liver injury vary worldwide, with limited data regarding drug-induced hepatotoxicity in Australia. This study sought to provide information about the incidence, causes and clinical manifestations of drug-induced hepatotoxicity. METHODS: A retrospective study was performed on all adult inpatients with abnormal liver ...
Müller Constanze - - 2013
Infections with Chlamydia pneumoniae cause several respiratory diseases, such as community-acquired pneumonia, bronchitis or sinusitis. Here, we present an integrated non-targeted metabolomics analysis applying ultra-high-resolution mass spectrometry and ultra-performance liquid chromatography mass spectrometry to determine metabolite alterations in C. pneumoniae-infected HEp-2 cells. Most important permutations are elaborated using uni- and ...
Lohmann K - - 2013
A number of genetic causes of movement disorders including Parkinson disease, dystonia, restless legs syndrome or essential tremor have been elucidated in recent years. This process was accelerated by novel technologies including genome-wide association studies (GWAS) and next generation sequencing (NGS). Although monogenic forms are overall rare, they provide a ...
Berghoff Anna S - - 2013
Upon disease progression on trastuzumab-based therapy, patients with HER-2 positive metastatic breast cancer (MBC) may switch to lapatinib or continue on trastuzumab. We aimed to assess the impact of both strategies on overall survival (OS) in all patients treated for HER-2 positive MBC at the Medical University Vienna from 1999 ...
Tribius S - - 2013
PURPOSE: Xerostomia is a debilitating side effect of radiotherapy in patients with head and neck cancer. We undertook a prospective study of the effect on xerostomia and outcomes of sparing one or both parotid glands during radiotherapy for patients with squamous cell carcinoma of the head and neck. METHODS AND ...
Khaireddin R - - 2013
BACKGROUND: Blepharitis due to Meibom gland dysfunction (MGD) is presumed to be one of the main reasons for dry eye symptoms which occur in up to 50% of contact lens users. Thus, MGD presumably plays an important role in dry eye in contact lens wearers. In the present prospective, randomized ...
Fagot Joël - - 2013
Analogical reasoning is a cornerstone of human cognition, but the extent and limits of analogical reasoning in animals remains unclear. Recent studies have demonstrated that apes and monkeys can match relations with relations, suggesting that these species have the basic abilities for analogical reasoning. However, analogical reasoning in humans entails ...
Poteet Steven A - - 2013
Visible light irradiation of a ruthenium(II) quinone-containing complex, [(phen)(2)Ru(phendione)](2+) (1(2+)), where phendione = 1,10-phenanthroline-5,6-dione, leads to DNA cleavage in an oxygen independent manner. A combination of NMR analyses, transient absorption spectroscopy, and fluorescence measurements in water and acetonitrile reveal that complex 1(2+) must be hydrated at the quinone functionality, giving ...
Kolle Mathias - - 2013
The concentrically-layered photonic structure found in the tropical fruit Margaritaria nobilis serves as inspiration for photonic fibers with mechanically tunable band-gap. The fibers show the spectral filtering capabilities of a planar Bragg stack while the microscopic curvature decreases the strong directional chromaticity associated with flat multilayers. Elongation of the elastic ...
Sattar N - - 2013
Whilst the interplay between type 2 diabetes and cardiovascular disease (CVD) has been recognised for many years, recent analyses of existing studies have helped refine several aspects of this relationship with relevance to clinical practice. First, recent data demonstrate that fasting glucose is not linearly related to CVD risk in ...
Eyo Ukpong B UB Department of Biology, University of Iowa, Iowa City, IA 52242, - - 2013
A century after Cajal identified a "third element" of the nervous system, many issues have been clarified about the identity and function of one of its major components, the microglia. Here, we review recent findings by microgliologists, highlighting results from imaging studies that are helping provide new views of microglial ...
Bürmann Frank - - 2013
Eukaryotic structural maintenance of chromosomes (SMC)-kleisin complexes form large, ring-shaped assemblies that promote accurate chromosome segregation. Their asymmetric structural core comprises SMC heterodimers that associate with both ends of a kleisin subunit. However, prokaryotic condensin Smc-ScpAB is composed of symmetric Smc homodimers associated with the kleisin ScpA in a postulated ...
Watrous Andrew J AJ Neuroscience Graduate Group, University of California, Davis, California, - - 2013
The medial temporal lobes, prefrontal cortex and parts of parietal cortex form the neural underpinnings of episodic memory, which includes remembering both where and when an event occurred. However, the manner in which these three regions interact during retrieval of spatial and temporal context remains untested. We employed simultaneous electrocorticographical ...
Vaagt Franziska - - 2013
Toxic mushroom species like the death cap (Amanita phalloides) are responsible for most mushroom poisonings. In the present work, novel loop-mediated isothermal amplification (LAMP) assays were used for the differentiation of even closely related edible and toxic mushroom species. The applicability of these methods was tested by cross-reaction studies and ...
Liu Zheng - - 2013
Graphene and hexagonal boron nitride (h-BN) have similar crystal structures with a lattice constant difference of only 2%. However, graphene is a zero-bandgap semiconductor with remarkably high carrier mobility at room temperature, whereas an atomically thin layer of h-BN is a dielectric with a wide bandgap of ∼5.9 eV. Accordingly, if ...
Beduschi M G - - 2013
Septic shock is a systemic inflammatory response syndrome, and it is the leading cause of death in intensive care units. Mycophenolate mofetil (MMF) is an immunosuppressant that has been shown to be effective in the treatment of various inflammatory diseases. In this study, the anti-inflammatory effect of MMF in a ...
Mermans J F - - 2013
BACKGROUND/PURPOSE: The purpose of this study was to investigate the influence of different located post surgical scars on both perfusion and redness. The pattern of change and correlation between perfusion and redness of post surgical scars is also examined. METHODS: In this study, we measured redness and perfusion of the ...
Liang Haihua - - 2013
The Salmonella PmrA/PmrB two-component system uses an iron(III)-binding motif on the cell surface to sense the environmental or host ferric level and regulate PmrA-controlled gene expression. We replaced the iron(III)-binding motif with a lanthanide-binding peptide sequence that is known to selectively recognize trivalent lanthanide ions. The newly engineered two-component system ...
Youn Je-In - - 2013
Two major populations of myeloid-derived suppressor cells (MDSCs), monocytic MDSCs (M-MDSCs) and polymorphonuclear MDSCs (PMN-MDSCs) regulate immune responses in cancer and other pathologic conditions. Under physiologic conditions, Ly6C(hi)Ly6G(-) inflammatory monocytes, which are the normal counterpart of M-MDSCs, differentiate into macrophages and dendritic cells. PMN-MDSCs are the predominant group of MDSCs ...
Shaymurat Talgar - - 2013
A room-temperature highly-sensitive SO(2) sensor with fast response and complete recovery was constructed based on gas dielectric field-effect transistor (FET) of CuPc single crystalline nanowire. The exposed conductive channel by gas dielectric is responsible for the high sensitivity to SO(2) and the adsorption of the SO(2) molecules dramatically enhances the ...
Baltanás Ana - - 2013
Aims: The NADPH oxidases constitute a major source of superoxide anion (•O2-) in hypertension. Several studies suggest an important role of NADPH oxidases in different effects mediated by TGF-β1. We investigated whether a chronic treatment with P144, a peptide synthesized from type III TGF-β1 receptor, inhibited NADPH oxidases in renal ...
Shan Yuxi - - 2013
Aims: Oxidative stress is thought to be involved in Friedreich's ataxia, yet it has not been demonstrated in Dorsal Root Ganglion (DRG) neurons that are first to degenerate. Using the YG8R mouse model of Friedreich's ataxia, microarray and neuritic growth experiments were carried out in DRG. Results: YG8R hemizygous mice ...
Lasarte-Aragonés Guillermo - - 2013
Extraction techniques are surface-dependent processes since their kinetic directly depends on the contact area between the sample and the extractant phase. The dispersion of the extractant (liquid or solid) increases this area improving the extraction efficiency. In this article, the dispersion of a nanostructured sorbent at the very low milligram ...
Coimbra Elaine S - - 2013
In this work, we report the antileishmanial evaluation of twenty 7-chloro-4-quinolinylhydrazone derivatives (1-20). Firstly, the compounds were tested against promastigotes of four different Leishmania species. After that, all derivatives were assayed against L. braziliensis amastigotes and murine macrophages. Furthermore, it was investigated if the antiamastigote L. braziliensis effect of the ...
Daruwalla Jurstine - - 2013
BACKGROUND: Fatigue has been shown to have a negative impact on surgical performance. However, there is a lack of research investigating its effect on laparoscopy, particularly in Australia. This study investigated whether fatigue associated with a surgeon's usual workday led to a measurable drop off in laparoscopic surgical skills as ...
Cheng Jinguang - - 2013
A new Bi(3)Ge(3)O(10.5) compound has been synthesized under high pressure, P = 7 GPa, and 700 °C. Instead of the pyrochlore that is normally stabilized under high pressure, the Bi(3)Ge(3)O(10.5) crystallizes in a KSbO(3)-ype crystal structure. The crystal structure has been refined by the Rietveld method from synchrotron X-ray diffraction ...
Liu G - - 2013
The high-temperature stability and mechanical properties of refractory molybdenum alloys are highly desirable for a wide range of critical applications. However, a long-standing problem for these alloys is that they suffer from low ductility and limited formability. Here we report a nanostructuring strategy that achieves Mo alloys with yield strength ...
Zhong Silin - - 2013
Ripening of tomato fruits is triggered by the plant hormone ethylene, but its effect is restricted by an unknown developmental cue to mature fruits containing viable seeds. To determine whether this cue involves epigenetic remodeling, we expose tomatoes to the methyltransferase inhibitor 5-azacytidine and find that they ripen prematurely. We ...
Bentsen Signe Berit - - 2013
This paper examines the prevalence of multiple symptoms and the relationships between future expectations and multiple symptoms in a cross-sectional study of 100 patients with chronic obstructive pulmonary disease. A questionnaire was used to examine the patients' symptoms of breathlessness, anxiety, depression, sleeplessness, fatigue, and pain, and their outlook for ...
Schwarz Frank - - 2013
OBJECTIVES: Mucosal recessions are a common finding following surgical treatment of peri-implantitis, thus compromising the overall esthetic outcome of implant therapy. This case series aimed at evaluating the clinical outcome of a combined surgical therapy of advanced peri-implantitis lesions with concomitant soft tissue volume augmentation. MATERIAL AND METHODS: Ten patients ...
Yu Shimeng - - 2013
Neuromorphic computing is an emerging computing paradigm beyond the conventional digital von Neumann computation. An oxide-based resistive switching memory has been engineered to emulate synaptic devices. At the device level, the gradual resistance modulation has been characterized by hundreds of identical pulses, achieving a low energy consumption of less than ...
Han Dong-Wook - - 2013
Porous and coarse (5 ~ 10 μm) LiFePO4/C composites with excellent electrochemical performance were synthesized by a growth technology using nano-structured (100 ~ 200 nm) LiFePO4 as seed crystals for 2nd crystallization process. The porous and coarse LiFePO4/C presented high initial discharge capacity (~ 155 mA h g-1 at 0.1 ...
Mitchell Rebecca - - 2013
AIM: To describe the research protocol that will be used to investigate factors contributing to effective interprofessional practice in a rural context in Australia. BACKGROUND: Interprofessional practice is a key strategy for overcoming rural health challenges; however, our knowledge of interprofessional initiatives and consequences in rural areas is limited. DESIGN: ...
Asberg Anders - - 2013
Long-term triple immunosuppressive therapy with cyclosporine (CsA), mycophenolate mofetil (MMF) and prednisolone may be excessively powerful for many transplant recipients. We compared withdrawal of either MMF or CsA in stable kidney transplants on triple immunosuppression. The study was a prospective, randomized, controlled 12-months trial in stable kidney transplants. The patients ...
Yu Peiqiang - - 2013
Heat-related processing of cereal grains, legume seeds and oil seeds could be used to improve nutrient availability in ruminants. However, different types of processing may have different impact on intrinsic structure of tissues. To date, there is little research on structure changes after processing within intact tissues. Synchrotron-based molecular imaging ...
Krüger M - - 2013
First clinical experiences with the organ care system (OCS) in lung transplantation showed that this device allows perfusion and ventilation of the lungs under practically physiological conditions. Some pulmonary pathologies necessitate ex situ operations, e.g. to avoid pneumonectomy. The objective of this work was to investigate the feasibility of ex ...
Hornillos Valentín - - 2013
A Cu(I)-phosphoramidite-based catalytic system that allows asymmetric allyl-allyl cross coupling with high enantioselectivity is reported. This transformation tolerates a large variety of functionalized substrates. The versatility of this new reaction is illustrated in the catalytic asymmetric synthesis of the Martinelline alkaloids chromene derivate-core.
Wirschell Maureen - - 2013
Primary ciliary dyskinesia (PCD) is characterized by dysfunction of respiratory cilia and sperm flagella and random determination of visceral asymmetry. Here, we identify the DRC1 subunit of the nexin-dynein regulatory complex (N-DRC), an axonemal structure critical for the regulation of dynein motors, and show that mutations in the gene encoding ...
Talirz Leopold - - 2013
Atomically precise graphene nanoribbons (GNRs) can be obtained via thermally induced polymerization of suitable precursor molecules on a metal surface. This communication discusses the atomic structure found at the termini of armchair GNRs obtained via this bottom-up approach. The short zigzag edge at the termini of the GNRs under study ...
Quansah Joycelyn K - - 2013
The effect of thermal and ultrasonic treatment of cowpea proteins (CP) on amino acid composition, radical scavenging and reducing potential of hydrolysates (CPH) obtained from in vitro simulated gastrointestinal digestion of CP was evaluated. Hydrolysis of native and treated CP with gastrointestinal pepsin and pancreatin yielded CPH that displayed antioxidant ...
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