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Results 551 - 600 of 4463
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Mohr Peter - - 2013
BACKGROUND: Previous studies have shown statistically significant differences in electrical impedance between various cutaneous lesions. Electrical impedance spectroscopy (EIS) may therefore be able to aid clinicians in differentiating between benign and malignant skin lesions. OBJECTIVES: The aim of the study was to develop a classification algorithm to distinguish between melanoma ...
Terzaki Konstantina - - 2013
Engineering artificial scaffolds that enhance cell adhesion and growth in three dimensions is essential to successful bone tissue engineering. However, the fabrication of three-dimensional (3D) tissue scaffolds exhibiting complex micro- and nano-features still remains a challenge. Few materials can be structured in three dimensions, and even those have not been ...
Motoyama N - - 2013
BACKGROUND: Platelet-activating factor (PAF) has been implicated in the pathology of neuropathic pain. Previous studies reported that PAF receptor (PAF-R) antagonists have varied anti-allodynia effects by route of administration and nerve injury models in rats. METHODS: The present study elucidated the effectiveness of PAF antagonists against neuropathic pain in four ...
Wiedemann Dominik - - 2013
A CT-scan of a 75-year-old patient showed an aneurysm of the descending aorta with a maximum diameter of 4.8 cm involving the left subclavian artery. Due to the fact that the patient had several comorbidities including a severe chronic obstructive pulmonary disease he was treated only conservatively. However, there were ...
Bayer J - - 2013
BACKGROUND: The aim was to survey the radiological diagnostics and type of primary radiological examination of polytraumatized patients treated in German hospitals at various levels in the three-tiered system. MATERIAL AND METHODS: A questionnaire was sent in October 2007 to every traumatology department registered in the DGU (German Society for ...
Dieckmann Arne - - 2013
The Diels-Alder reactions of cyclic linear and cross-conjugated trienamines with oxindoles have been studied with density functional theory [M06-2X/def2-TZVPP/IEFPCM//B97D/6-31+G(d,p)/IEFPCM]. These reactions are found to proceed in a stepwise fashion. Computations revealed that these transformations involve complex mechanisms including zwitterionic intermediates and several unstable alternate cycloadducts arising from (2+2) cycloadditions and ...
Luo Jiayan - - 2013
Graphene is considered as a promising ultracapacitor material toward high power and energy density because of its high conductivity and high surface area without pore tortuosity. However, the two-dimensional (2D) sheets tend to aggregate during electrode fabrication process and align perpendicular to the flow direction of electrons and ions, which ...
Park Chan Sun - - 2013
Sodium ion batteries (SIBs) have many advantages such as the low price and abundance of sodium raw materials that are suitable for large-scale energy storage applications. Herein, we report a Mn-based pyrophosphate, Na2MnP2O7, as a new SIB cathode material. Unlike most Mn-based cathode materials that suffer severely from sluggish kinetics, ...
Tréguer Karine - - 2013
The objective of the present study was to characterize the nature of the autocrine/paracrine signal within human adipose tissue that may alter glucose metabolism and the inflammatory status in adipocytes. We prepared a conditioned medium from abdominal dermolipectomies in the absence (CM) or the presence (CMBSA) of bovine serum albumin ...
Streibel T - - 2013
In this study, the chemical composition of sidestream smoke (SSS) emissions of cigarettes are characterised using a laser-based single-photon ionisation time-of-flight mass spectrometer. SSS is generated from various cigarette types (2R4F research cigarette; Burley, Oriental and Virginia single-tobacco-type cigarettes) smoked on a single-port smoking machine and collected using a so-called ...
Mohd Fauzi Fazlin - - 2013
Traditional Chinese medicine (TCM) and Ayurveda have been used in humans for thousands of years. While the link to a particular indication has been established in man, the mode-of-action (MOA) of the formulations often remains unknown. In this study, we aim to understand the MOA of formulations used in traditional ...
Tan Winson Jianhong - - 2013
BACKGROUND: Although useful in evaluation of suspected appendicitis, not all patients require computed tomography (CT) evaluation. Clinical stratification of patients who benefit from CT evaluation is essential. We utilize the Alvarado score (AS) to stratify patients with suspected appendicitis into subgroups who benefit from CT evaluation and propose an objective ...
Retzke J D - - 2013
OBJECTIVES: To compare three methods of cervical length measurements using ultrasound in the first trimester: single-line, two-line, and tracing. METHODS: Images appropriate for cervical length measurements were obtained using transvaginal ultrasound between 11 + 0 and 13 + 6 weeks' gestation. The cervix was measured on stored images using three methods: a single straight line, ...
Chainani Edward T - - 2013
Levitated drops show potential as microreactors, especially when radicals are present as reactants or products. Solid/liquid interfaces are absent or minimized, avoiding adsorption and interfacial reaction of conventional microfluidics. We report amperometric detection in an acoustically levitated drop with simultaneous ballistic addition of reactant. A gold microelectrode sensor was fabricated ...
Wahl Benoit - - 2013
The palladium-catalyzed alkoxycarbonylation of an alpha-chloroketone can be efficiently combined to a Michael addition reaction in a new two-step domino reaction, allowing the synthesis of original highly functionalized alpha-alkylated-beta-ketoesters. The scope of the reaction was extended to several alpha-chloroketones and Michael acceptors with moderate to very good yields.
Roman Heather B - - 2013
Aims: To define the consequences of loss of cysteine dioxygenase (CDO) on cysteine metabolism at the tissue level, we determined levels of relevant metabolites and enzymes and evidence of H2S/HS‒ toxicity in liver, pancreas, kidney and lung of CDO-/- mice fed either a taurine-free or taurine-supplemented diet. Results: CDO-/- mice ...
Kim Dong-Hyun - - 2013
Hybrid nanoarchitectures are among the most promising nanotechnology-enabled materials for biomedical applications. Interfacing of nanoparticles with active materials gives rise to the structures with unique multiple functionality. SPION particles are widely employed in the biology and in developing of advanced medical technologies. Polymeric micelles offer the advantage of multifunctional carriers ...
Nikom Jaru - - 2013
3D interconnected porous scaffolds of HA and HA with various additions of SiO(2) were fabricated using a polymeric template technique, to make bioceramic scaffolds consisting of macrostructures of the interconnected macropores. Three different sizes of the polyurethane template were used in the fabrication process to form different size interconnected macropores, ...
Kochanski Ryan - - 2013
Ethanol provides neuroprotection following ischemia/reperfusion. The present study assessed ethanol's effect on hyperglycolysis and NADPH oxidase (NOX) activation. Adult, male Sprague-Dawley rats were subjected to middle cerebral artery occlusion (MCAO) for 2 hours. Three sets of experiments were conducted to determine ethanol's effect on: 1) conferring neuroprotection by measuring infarct ...
Hashemi M - - 2013
In this study we aimed to evaluate the possible association of PTPN22 rs2476601 as well as epidermal growth factor receptor (EGFR) rs17337023 gene polymorphism and rheumatoid arthritis (RA) in a sample of Iranian population. This case-control study was performed on 120 patients with RA and 120 healthy subjects. Genomic DNA ...
Fernandes Nikhil J - - 2013
We report an ionic hybrid based on silica nanoparticles as the anion and amine-terminated polyethylene glycol (PEG) as a cation. The charge on the nanoparticle anion is carried by the surface hydroxyls. SAXS and TEM reveal an exceptional degree of dispersion of the silica in the polymer and high degree ...
Lee Sun-Mi - - 2013
Antitumor and antiangiogenic active dendritic compounds conjugated with 5-fluorouracil (5-FU) were synthesized and characterized. First, the core structure based on ascorbic acid and dicarboxylic acid was synthesized, amidated with ethylenediamine. For the synthesis of higher generated dendrimer, it was reacted further with methyl acrylate to increase molecular weight through Michael ...
Hu Jinxuan - - 2013
Spent sorbents in water treatment processes have potential risks to the environment if released without proper treatment. The aim of this work was to investigate the potential regeneration of commercially prepared nano-TiO(2) (anatase) for the removal of Pb (II), Cu (II), and Zn (II) by pH 2 and ethylenediaminetetraacetic acid (EDTA) ...
Ido Shinichiro - - 2013
The DNA double helix was first elucidated by J. D. Watson and F. H. C. Crick over a half century ago. However, no one could actually "see" the well-known structure ever. Among all real-space observation methods, only atomic force microscopy (AFM) enables us to visualize the biologically active structure of ...
Li Yi - - 2013
BACKGROUND: Increasing evidence shows that vascular compression on any of the four zones of facial nerve may cause hemifacial spasms. Vascular compression on zone 4 (the cisternal portion) of the nerve is quite common, but only a very small percentage of such compression will elicit hemifacial spasm, because zone 4 ...
Higashijima Ai - - 2013
OBJECTIVE: The aim of this study was to characterize placenta-specific microRNAs in fetal growth restriction (FGR) pregnancy. METHOD: Placenta-specific miRNAs were identified by next-generation sequencing analysis. Subsequently, quantitative real-time reverse-transcription polymerase chain reaction was used to identify FGR placenta-specific miRNAs whose level of expression was significantly decreased in FGR placenta ...
Heilbronn Cherie - - 2013
INTRODUCTION AND AIMS: Concern about the non-medical use of quetiapine and related acute harms is growing. Case series cite quetiapine as a potential drug of misuse, while recent research questions its relative safety in comparison with other atypical antipsychotic preparations. This paper explores population-level patterns of quetiapine-related ambulance attendances over ...
Pengo Niccolò - - 2013
The role of autophagy in plasma cells is unknown. Here we found notable autophagic activity in both differentiating and long-lived plasma cells and investigated its function through the use of mice with conditional deficiency in the essential autophagic molecule Atg5 in B cells. Atg5(-/-) differentiating plasma cells had a larger ...
Zhang Ming-Tian - - 2013
A self-assembly formed, tri-glycylglycine macrocyclic ligand (TGG4-) complex of Cu(II), [(TGG4-)CuII-OH2]2-, efficiently catalyzes water oxidation in a phosphate buffer at pH = 11 at room temperature by a well-defined mechanism. In the mechanism, initial oxidation to Cu(III) is followed by further oxidation to a formal "Cu(IV)" with formation of a ...
Bahat Anat - - 2013
TAF4b is a cell type-specific subunit of the general transcription factor TFIID. Here, we show that TAF4b is highly expressed in embryonic stem cells (ESC) and is down-regulated upon differentiation. To examine the role of TAF4b in ESC, we applied a knockdown (KD) approach. TAF4b depletion is associated with morphological ...
Zhao M X - - 2013
During the months of May and June in the year 2007, a survey was conducted regarding coral reef communities in the remote atolls (Zhubi Reef and Meiji Reef) of Nansha Islands, southern South China Sea. The goals of the survey were to: (1) for the first time, compile a scleractinian ...
Fan Feng-Jia - - 2013
The wurtzite-derived Cu2ZnSn(S1-xSex)4 alloys are studied for the first time through combining the theoretical calculations and the experimental characterizations. Ab initio calculations predict that wurtzite-derived Cu2ZnSnS4 and Cu2ZnSnSe4 are highly miscible, and the bandgaps of the mixed-anion alloys can be linearly tuned from 1.0 to 1.5 eV through changing the ...
Li Shijun - - 2013
We describe the fabrication of a suite of [3]catenanes, obtained via the multi-component coordination-driven self-assembly and host-guest complexation of a rectangular scaffold comprising a 90° Pt-based acceptor building block with a pseudorotaxane bis(pyridinium)ethane/dibenzo[24]crown-8 linear dipyridyl ligand and three dicarboxylate donors. The doubly threaded [3]catenanes are formed from ten total molecular ...
Elam W Austin - - 2013
The native states of globular proteins have been accessed in atomic detail by X-ray crystallography and nuclear magnetic resonance spectroscopy, yet characterization of denatured proteins beyond global metrics has proven to be elusive. Denatured proteins have been observed to exhibit global geometric properties of a random coil polymer. However, this ...
Liscio Fabiola - - 2013
Charge transport in organic thin film transistors takes place in the first few molecular layers in contact with the gate dielectric. Here we demonstrate that the charge transport pathways in these devices are extremely sensitive to the orientational defects of the first monolayers, which arise from specific growth conditions. Although ...
Liang Haihua - - 2013
The Salmonella PmrA/PmrB two-component system uses an iron(III)-binding motif on the cell surface to sense the environmental or host ferric level and regulate PmrA-controlled gene expression. We replaced the iron(III)-binding motif with a lanthanide-binding peptide sequence that is known to selectively recognize trivalent lanthanide ions. The newly engineered two-component system ...
Shaymurat Talgar - - 2013
A room-temperature highly-sensitive SO(2) sensor with fast response and complete recovery was constructed based on gas dielectric field-effect transistor (FET) of CuPc single crystalline nanowire. The exposed conductive channel by gas dielectric is responsible for the high sensitivity to SO(2) and the adsorption of the SO(2) molecules dramatically enhances the ...
Baltanás Ana - - 2013
Aims: The NADPH oxidases constitute a major source of superoxide anion (•O2-) in hypertension. Several studies suggest an important role of NADPH oxidases in different effects mediated by TGF-β1. We investigated whether a chronic treatment with P144, a peptide synthesized from type III TGF-β1 receptor, inhibited NADPH oxidases in renal ...
Shan Yuxi - - 2013
Aims: Oxidative stress is thought to be involved in Friedreich's ataxia, yet it has not been demonstrated in Dorsal Root Ganglion (DRG) neurons that are first to degenerate. Using the YG8R mouse model of Friedreich's ataxia, microarray and neuritic growth experiments were carried out in DRG. Results: YG8R hemizygous mice ...
Kang Yijin - - 2013
Well-defined surfaces of Pt have been extensively studied for various catalytic processes. However, industrial catalysts are mostly composed of fine particles (e.g. nanocrystals), due to the desire for a high surface to volume ratio. Therefore, it is very important to explore and understand the catalytic processes both at nanoscale and ...
Greene Jessica - - 2013
OBJECTIVE: This study examines the impact of Australia's pay-for-performance (P4P) program for general practitioners (GPs). The voluntary program pays GPs A$40 and A$100 in addition to fee-for-service payment for providing patients recommended diabetes and asthma treatment over a year, and A$35 for screening women for cervical cancer who have not ...
Ameur S - - 2013
A cloud point extraction coupled with high performance liquid chromatography (HPLC/UV) method was developed for the determination of Δ(9)-tetrahydrocannabinol (THC) in micellar phase. The nonionic surfactant "Dowfax 20B102" was used to extract and pre-concentrate THC from cannabis resin, prior to its determination with a HPLC-UV system (diode array detector) with ...
Cheng Linli - - 2013
Methyl-3-quinoxaline-2-carboxylic acid (MQCA) is a possible residue marker for three quinoxaline veterinary medicines (olaquindox, mequindox, and quinocetone). The wide application of mequindox/quinocetone or the illegal use of olaquindox leads to MQCA residue in animal's original food, thereby threatening the safety of human food. The indirect competitive enzyme-linked immunosorbent assay (IC-ELISA) ...
Mitchell Rebecca - - 2013
AIM: To describe the research protocol that will be used to investigate factors contributing to effective interprofessional practice in a rural context in Australia. BACKGROUND: Interprofessional practice is a key strategy for overcoming rural health challenges; however, our knowledge of interprofessional initiatives and consequences in rural areas is limited. DESIGN: ...
Asberg Anders - - 2013
Long-term triple immunosuppressive therapy with cyclosporine (CsA), mycophenolate mofetil (MMF) and prednisolone may be excessively powerful for many transplant recipients. We compared withdrawal of either MMF or CsA in stable kidney transplants on triple immunosuppression. The study was a prospective, randomized, controlled 12-months trial in stable kidney transplants. The patients ...
Yu Peiqiang - - 2013
Heat-related processing of cereal grains, legume seeds and oil seeds could be used to improve nutrient availability in ruminants. However, different types of processing may have different impact on intrinsic structure of tissues. To date, there is little research on structure changes after processing within intact tissues. Synchrotron-based molecular imaging ...
Krüger M - - 2013
First clinical experiences with the organ care system (OCS) in lung transplantation showed that this device allows perfusion and ventilation of the lungs under practically physiological conditions. Some pulmonary pathologies necessitate ex situ operations, e.g. to avoid pneumonectomy. The objective of this work was to investigate the feasibility of ex ...
Hornillos Valentín - - 2013
A Cu(I)-phosphoramidite-based catalytic system that allows asymmetric allyl-allyl cross coupling with high enantioselectivity is reported. This transformation tolerates a large variety of functionalized substrates. The versatility of this new reaction is illustrated in the catalytic asymmetric synthesis of the Martinelline alkaloids chromene derivate-core.
Catalano Peter J - - 2013
Balloon dilation technology (BDT), also known as balloon sinuplasty, has been in clinical use since September, 2005. Prior to BDT, surgeons performed a procedure called FESS, or functional endoscopic sinus surgery, for patients with chronic sinusitis. As is true with any new technology or procedure in medicine, a debate often ...
Douglas R G - - 2013
The renin-angiotensin system (RAS) is central to regulation of blood pressure and electrolyte homeostasis. Angiotensin-converting enzyme (ACE), a key protease in the RAS, has a range of substrates, including N-acetyl-Ser-Asp-Lys-Pro (Ac-SDKP). Ac-SDKP is cleared almost exclusively by ACE and specifically by the N-domain active site of this enzyme. Ac-SDKP is ...
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