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 Results 501 - 550 of 4464 < 6 7 8 9 10 11 12 13 14 15 16 > 501 Bektas Ozden Ozel - - 2013 Abstract Objective. The main objective of this study was to evaluate the effects of an at-home and two in-office (chemically activated and KTP laser-activated) bleaching methods on the microleakage of composite resin restorations bonded with etch-and-rinse and self-etch adhesive systems. Materials and methods. Class V cavity preparations were performed on ... 502 Li T - - 2013 Caudal-related homeobox 1 (CDX1), an intestinal-specific transcription factor, has been reported to have vital roles in gastric intestinal metaplasia (IM). Although IM is a high-risk factor for gastric cancer (GC), the specific role of CDX1 in GC is largely unknown. In this study, we investigated the expression of CDX1 and ... 503 Lillioja Stephen S Illawarra Health and Medical Research Institute, University of Wollongong, Northfields Avenue, NSW 2522, Australia. - - 2013 Higher whole grain cereal intakes are associated with substantially lower risks of type 2 diabetes, coronary heart disease, and hypertension. These reduced risks have been established in large prospective studies that now include millions of person-years of follow-up. We analyze the results of 11 major prospective studies to provide recommendations ... 504 Sonaa Elango - - 2013 Behavioral difference of cancer cells and normal cells to anticancer drugs is diverse. Debilitating side effects observed with certain chemotherapeutic and prophylactic anticancer drugs have lead to identification of natural agents that may offer protective role against the damage induced in normal cells. The present study aimed to determine the ... 505 Spielmann P M - - 2013 Background: Lesions arising in the external auditory canal that require surgical excision are uncommon. They are associated with a range of pathologies, including bony abnormalities, infections, benign and malignant neoplasms, and epithelial disorders. Methods: This paper describes a 10-year personal case series of external auditory canal lesions with chart, imaging ... 506 Bazarbachi A - - 2013 Allogeneic hematopoietic cell transplantation (HCT) activity significantly increased in the Eastern Mediterranean area over the past decade. However, comparative outcomes with longer established centers, especially European Blood and Marrow Transplantation (EBMT) centers, have not been reported. We compared outcomes of matched-sibling allogeneic HCT between East Mediterranean Blood and Marrow Transplantation ... 507 Munteanu Sorin - - 2013 Surface chemical reactivity is imaged by combining electrochemical activation of a surface transformation process with spatio-temporal ellipsometric microscopy. An imaging ellipsometric microscope is built, allowing ellipsometric images of surfaces with a lateral resolution of ~1 µm and a thickness sensitivity of ~0.1 nm in air and 0.4 nm in a ... 508 Muzzio Damián - - 2013 B lymphocytes are pleiotropic cells belonging to the adaptive arm of the immune system. Although B cells were classically regarded for their capacity to produce antibodies, in the recent years, several other functions were attributed to these cells. B cells can uptake, process and present antigens as well as produce ... 509 Wang Xiaogu - - 2013 Synthetic octacalcium phosphate (OCP) has been suggested to be a useful biomaterial for the regeneration of hard tissues, including bone. However, it remains unknown whether OCP induces dentine formation by dental pulp. We investigated biomineralization of dental pulp exposed to synthetic OCP in vitro and in vivo. When dental pulp ... 510 Abtew Tesfaye - - 2013 Electronic and magnetic properties of graphene-ferromagnet interfaces are investigated using first-principles electronic structure methods in which a single layer graphene is adsorbed on Ni(111) and Co(111) surfaces. Due to the symmetry matching and orbital overlap, the hybridization between graphene pπ and Ni (or Co) d(z(2)) states is very strong. This ... 511 Routtenberg Aryeh - - 2013 It is here proposed that the evanescent network derived from malleable or supple synapses is the substrate for long-lasting memory. The subjective sense of memory permanence is not derived, as suggested by Bain and others, from the stabilization of synaptic structure which gives rise to consolidated distributed networks. This generally ... 512 Guizetti Julien - - 2013 Phenotypic variation in genetically identical malaria parasites is an emerging topic. Although antigenic variation is only part of a more global parasite strategy to create adaptation through epigenetically controlled transcriptional variability, it is the central mechanism enabling immune evasion and promoting pathogenesis. The var gene family is the best-studied example ... 513 Avila M L - - 2013 BACKGROUND: Heparin-induced-thrombocytopenia (HIT) has increasingly been reported in children as an indication for use of new alternative anticoagulant drugs (NAADs). OBJECTIVES: To systematically review the literature regarding: a) the incidence and prevalence of seroconversion and HIT and b) the clinical/laboratory findings and management of HIT in children. DESIGN/METHODS: MEDLINE and ... 514 He Yan - - 2013 Abstract Context: Astilbin is considered to be a new and promising immunosuppressant for immune related diseases, but limited in clinical application due to its poor water solubility, difficult oral absorption and low bioavailability. Objective: The present work studied the effect of PVP and surfactant combined carrier on its capability to ... 515 Ladeira Carina - - 2013 The International Agency for Research on Cancer classified formaldehyde as carcinogenic to humans because there is "sufficient epidemiological evidence that it causes nasopharyngeal cancer in humans". Genes involved in DNA repair and maintenance of genome integrity are critically involved in protecting against mutations that lead to cancer and/or inherited genetic ... 516 Fanali Gabriella - - 2013 Given the ability of human serum albumin (HSA) to bind hydrophobic ligands, the binding mode of α-tocopherol, the most representative member of the vitamin E family, is reported. α-Tocopherol binds to HSA with K $_{\rm d}^0$ = (7.0 ± 3.0) × 10(-6) M (pH 7.2, 25.0°C). Competitive and allosteric modulation ... 517 Sperança Adriane - - 2013 This report describes the synthesis of 4-organoselenyl-isoxazoles via FeCl3/RSeSeR-mediated intramolecular cyclization of alkynone O-methyloximes. The optimized conditions allowed the cyclization to proceed at room temperature, under ambient atmosphere and the reaction requires a short time to be completed. The reaction conditions tolerated neutral, electron-donating and electron-withdrawing groups present in both ... 518 Lomniczi Alejandro A Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA. - - 2013 The timing of puberty is controlled by many genes. The elements coordinating this process have not, however, been identified. Here we show that an epigenetic mechanism of transcriptional repression times the initiation of female puberty in rats. We identify silencers of the Polycomb group (PcG) as principal contributors to this ... 519 Chou Jonathan J Department of Anatomy, University of California, San Francisco, 94143-0452, - - 2013 Despite advances in our understanding of breast cancer, patients with metastatic disease have poor prognoses. GATA3 is a transcription factor that specifies and maintains mammary luminal epithelial cell fate, and its expression is lost in breast cancer, correlating with a worse prognosis in human patients. Here, we show that GATA3 ... 520 Miranda-Utrera Natalia - - 2013 BACKGROUND: In 2005, our center started a donation after cardiac death (DACD) program, by which patients who present an irreversible cardiac arrest outside hospital are brought to our center with the purpose of organ donation. We reviewed the outcomes of our program of kidney transplants from DACD. METHODS: We conducted ... 521 Shafiei Farbod - - 2013 The lack of symmetry between electric and magnetic charges, a fundamental consequence of the small value of the fine-structure constant, is directly related to the weakness of magnetic effects in optical materials. Properly tailored plasmonic nanoclusters have been proposed recently to induce artificial optical magnetism based on the principle that ... 522 LeBleu Valerie S VS Department of Medicine, Beth Israel Deaconess Medical Center, Division of Matrix Biology, Boston, Massachusetts, - - 2013 The functional contribution of myofibroblasts in fibrosis is not well understood. Using a new genetic mouse model to track and isolate myofibroblasts, we performed gene expression profiling followed by biological validation to identify HE4 (encoding human epididymis protein 4, also known as WAP 4-disulfide core domain-2 or Wfdc2) as the ... 523 Alamillo Christina M L - - 2013 This study aimed to assess the efficacy of first-trimester aneuploidy screening in a single clinical setting. Maternal age, nuchal translucency, and maternal serum levels of pregnancy-associated plasma protein A and free beta human chorionic gonadotrophin comprised first-trimester risk assessment for Down syndrome and trisomies 13/18. Means, screen positive rates, detection ... 524 Qiu Huawei - - 2013 Recombinant human thyroid stimulating hormone (rhTSH or Thyrogen®) has been approved for thyroid cancer diagnostics and treatment under a multidose regimen due to its short circulating half-life. To reduce dosing frequency, PEGylation strategies were explored to increase the duration of action of rhTSH. Lysine and N-terminal PEGylation resulted in heterogeneous ... 525 Mohr Peter - - 2013 BACKGROUND: Previous studies have shown statistically significant differences in electrical impedance between various cutaneous lesions. Electrical impedance spectroscopy (EIS) may therefore be able to aid clinicians in differentiating between benign and malignant skin lesions. OBJECTIVES: The aim of the study was to develop a classification algorithm to distinguish between melanoma ... 526 Parizotto Eneida A EA Department of Biochemistry, University of Oxford, Oxford, - - 2013 Oligomeric complexes of Trax and Translin proteins, known as C3POs, participate in several eukaryotic nucleic acid metabolism pathways, including RNA interference and tRNA processing. In RNA interference in humans and Drosophila, C3PO activates the RNA-induced silencing complex (RISC) by removing the passenger strand of the small interfering RNA precursor duplex, ... 527 Aghayeva Ulkar Firudin - - 2013 To date, a number of biomolecule-mediated nanoparticle self-assembly systems have been developed that are amenable to controllable disassembly under relatively gentle conditions. However, for some applications such as design of self-assembled multifunctional theragnostic agents, high stability of the assembled structures can be of primary importance. Here, we report extraordinarily high ... 528 Fu Yue Y Department of Chemistry, Indiana University, Bloomington, Indiana, - - 2013 Copper resistance has emerged as an important virulence determinant of microbial pathogens. In Streptococcus pneumoniae, copper resistance is mediated by the copper-responsive repressor CopY, CupA and the copper-effluxing P(1B)-type ATPase CopA. We show here that CupA is a previously uncharacterized cell membrane-anchored Cu(I) chaperone and that a Cu(I) binding-competent, membrane-localized ... 529 Mauriège P - - 2013 This study was performed to examine whether changes in subcutaneous adipose tissue (SCAT) metabolism indices after weight loss were related to the magnitude of weight regain. Nine men and ten premenopausal women whose body mass index ranged from 30 to 42 kg/m(2), 35-48 years old, were studied before and after a 15-week ... 530 Joo Wonil - - 2013 The objective of this study is to clearly and precisely describe the topography and contents of the infratemporal fossa. Ten formalin-fixed, adult cadaveric specimens were studied. Twenty infratemporal fossa were dissected and examined using micro-operative techniques with magnifications of 3-40×. Information was obtained about the inter-relationships of the contents of ... 531 Steiner Martina - - 2013 Pretargeting approaches consist in the injection of bispecific antibodies capable of recognizing both an accessible disease marker and a small ligand, which is typically administered at a later stage and which serves as delivery vehicle of a payload for imaging or therapy applications. In the oncology field, pretargeting strategies have ... 532 Manfredini Fabio F Department of Entomology, Center for Pollinator Research, Pennsylvania State University, University Park, PA 16802, USA. - - 2013 Successful invaders often become established in new ranges by outcompeting native species. The "evolution of increased competitive ability" hypothesis predicts that invasive species are subjected to less predation and parasitization than sympatric native species, and thus can allocate resources from defence and immunity to growth and fecundity, thereby achieving higher ... 533 Snyder Rebecca A - - 2013 Expansion of the donor pool with expanded criteria donors and donation after cardiac death (DCD) donors is essential. DCD grafts result in increased rates of primary non-function (PNF) and delayed graft function (DGF). However, long-term patient and graft survival is similar between donation after brain death (DBD) donors and DCD ... 534 Harrison John D - - 2013 The mylohyoid hiatus and hernia were discovered in the nineteenth century and were considered to explain the origin of the plunging ranula from the sublingual gland. This formed the rationale for sublingual sialadenectomy for the treatment of plunging ranula. However, a more recent, extensive histological investigation reported that hernias contained ... 535 Li Weiping - - 2013 A highly sensitive chemiluminescence (CL) immunoassay was incorporated into a low-cost microfluidic paper-based analytical device (μ-PAD) to fabricate a facile paper-based CL immunodevice (denoted as μ-PCLI). This μ-PCLI was constructed by covalently immobilizing capture antibody on a chitosan membrane modified μ-PADs, which was developed by simple wax printing methodology. TiO(2) ... 536 Dalby R B - - 2013 OBJECTIVE: To explore the relationship between brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF), cerebral deep white matter lesions (DWMLs), and measures of white matter integrity in patients with late-onset depression, with respect to vascular risk factors. METHOD: We examined 22 patients with late-onset depression and 22 matched ... 537 Oeken J - - 2013 INTRODUCTION: It is recommended that a stapedotomy be performed under local anaesthesia to enable intraoperative monitoring of hearing and vestibular function. In contrast, we prefer to carry out stapedotomies under general anesthesia. The aim of this study was to investigate whether this practice has an adverse effect on hearing results. ... 538 Kostrominova Tatiana Y - - 2013 The musculoskeletal system (muscle-tendon-bone) demonstrates numerous age-related changes, with modifications in tendons the least well studied, although increased predisposition to tendinopathy and rupture have been reported. In order to gain insights into the basis of age-associated increase in tendon injuries, we compared Achilles and tibialis anterior tendons and myotendinous junctions ... 539 Kiang Jennifer D - - 2013 Microscale and nanoscale surface topography changes can influence cell functions, including morphology. Although in vitro responses to static topography are novel, cells in vivo constantly remodel topography. To better understand how cells respond to changes in topography over time, we developed a soft polyacrylamide hydrogel with magnetic nickel microwires randomly ... 540 DeMuth Peter C PC Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, - - 2013 DNA vaccines have many potential benefits but have failed to generate robust immune responses in humans. Recently, methods such as in vivo electroporation have demonstrated improved performance, but an optimal strategy for safe, reproducible, and pain-free DNA vaccination remains elusive. Here we report an approach for rapid implantation of vaccine-loaded ... 541 Feng Meng - - 2013 Many colonies of macaques (Macaca fascicularis and Macaca mulatta) are maintained in China, especially in Guangxi and Guizhou. A total of 803 fresh stool samples infected with Entamoeba were obtained from three big colonies of macaques located in southwest China. The samples were examined for the presence of five Entamoeba ... 542 Morris Luc G T LG Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, - - 2013 Aberrant Wnt signaling can drive cancer development. In many cancer types, the genetic basis of Wnt pathway activation remains incompletely understood. Here, we report recurrent somatic mutations of the Drosophila melanogaster tumor suppressor-related gene FAT1 in glioblastoma (20.5%), colorectal cancer (7.7%), and head and neck cancer (6.7%). FAT1 encodes a ... 543 van Dongen Stijn F M - - 2013 There's an APP for that: cell-repellent APP (azido-[polylysine-g-PEG]) is used to create substrates for spatially controlled dynamic cell adhesion. The simple addition of a functional peptide to the culture medium rapidly triggers cell adhesion. This highly accessible yet powerful technique allows diverse applications, demonstrated through tissue motility assays, patterned coculturing ... 544 Zhang Hui - - 2013 Intercropping and rotating banana (Musa spp.) with Chinese chive (Allium tuberosum Rottler) has been used as an effective method to control Panama disease (Fusarium wilt) of banana in South China. However, the underlying mechanism is unknown. In this study, we used aqueous leachates and volatiles from Chinese chive to evaluate ... 545 Varshney Rajeev K - - 2013 Chickpea (Cicer arietinum) is the second most widely grown legume crop after soybean, accounting for a substantial proportion of human dietary nitrogen intake and playing a crucial role in food security in developing countries. We report the ∼738-Mb draft whole genome shotgun sequence of CDC Frontier, a kabuli chickpea variety, ... 546 Jacobs Tevis D B - - 2013 Wear of sliding contacts leads to energy dissipation and device failure, resulting in massive economic and environmental costs. Typically, wear phenomena are described empirically, because physical and chemical interactions at sliding interfaces are not fully understood at any length scale. Fundamental insights from individual nanoscale contacts are crucial for understanding ... 547 Nawka T - - 2013 Microlaryngoscopy is a reliable technique and the most frequently applied method in laryngeal surgery. The design of new laryngoscopes and the application of video endoscopes may permit further improvements in laryngeal exposure, whilst minimizing the damage caused by their insertion. In contrast to this, the principle microsurgical procedures for improvement, ... 548 Hansen Pernille B L - - 2013 Calcium channel blockers are widely used to treat hypertension because they inhibit voltage-gated calcium channels that mediate transmembrane calcium influx in e.g. vascular smooth muscle and cardiomyocytes. The calcium channel family consists of several subfamilies, of which the L-type is usually associated with vascular contractility. However, the L-, T- and ... 549 Wiesner Melanie - - 2013 Thirteen different pak choi (Brassica rapa ssp. chinensis) cultivars were characterized regarding their glucosinolate profile analyzed by HPLC-DAD-MS. The identified glucosinolates were subjected to principal component analysis and three distinct groups of pak choi sprouts were identified. Group differences were marked mainly by variations in the aliphatic glucosinolate profile such ... 550 Stout Molly J MJ Department of Obstetrics and Gynecology, Washington University in Saint Louis, St. Louis, MO, USA. - - 2013 The aim of this study was to estimate the incidence of single umbilical artery (SUA) in twin pregnancies and to investigate whether SUA in twin gestations is associated with adverse obstetric outcomes. We performed a retrospective cohort study of consecutive twin pregnancies over 17 years at a tertiary care hospital. ... < 6 7 8 9 10 11 12 13 14 15 16 >