Search Results
Results 401 - 450 of 2825
< 4 5 6 7 8 9 10 11 12 13 14 >
McClaren Belinda J - - 2013
Purpose:Newborn screening for cystic fibrosis is increasingly available, but cascade testing following the diagnosis in a child has received little attention. We previously reported low levels of cascade testing over time, and this study investigated motivators as well as barriers to testing.Methods:Parents were interviewed about communicating the genetic information and ...
Chaijale Nayla N - - 2013
Classically, opioids produce their effects by activating Gi-proteins that inhibit adenylate cyclase activity. Previous studies proposed that mu-opioid receptors can also stimulate adenylate cyclase due to an initial transient coupling to Gs-proteins. Treatment with ultra-low doses of the nonselective opioid antagonist (-)-naloxone or its inactive enantiomer (+)-naloxone blocks this excitatory ...
Whitehead Kimberley - - 2013
PURPOSE: Although differences in illness perceptions between neurologists and patients with epilepsy or psychogenic nonepileptic seizures (PNES) are likely to be clinically relevant, this is the first study to attempt a direct comparison. In addition, this study compares the illness perceptions of patients with epilepsy with those of patients with ...
Lee C K - - 2013
BACKGROUND: Risk of transfusion-transmitted bacterial sepsis has been substantially reduced by a bacterial surveillance program (BST). However, new problems emerge as asymptomatic bacteremia is detected in blood donors. Streptococcus bovis bacteremia, which is known to associate with infective endocarditis and colonic carcinoma, is an example. STUDY DESIGN AND METHODS: A ...
Chen Xinai - - 2013
The origin recognition complex (ORC) is a pivotal element in DNA replication, heterochromatin assembly, checkpoint regulation, and chromosome assembly. Although the functions of the ORC have been determined in yeast and model animals, they remain largely unknown in the plant kingdom. In this study, OsORC3 (Oryza sativa Origin Recognition Complex ...
Berkman Paul J - - 2013
SUMMARY: Despite the international significance of wheat, its large and complex genome hinders genome sequencing efforts. To assess the impact of selection on this genome, we have assembled genomic regions representing genes for chromosomes 7A, 7B and 7D. We demonstrate that the dispersion of wheat to new environments has shaped ...
Beall Cynthia M - - 2013
OBJECTIVES: This report presents a perspective on the broad research trends in the biology of human populations at high-altitude and their contributions to the improved understanding of evolution and adaptation. A focus is on the research that has occurred over the past 50 years of anthropological fieldwork on the Andean, ...
Ebrahim Irshaad O - - 2013
This review provides a qualitative assessment of all known scientific studies on the impact of alcohol ingestion on nocturnal sleep in healthy volunteer's. At all dosages, alcohol causes a reduction in sleep onset latency, a more consolidated first half sleep and an increase in sleep disruption in the second half ...
Chao Yin-Kai - - 2013
ABSTRACT BACKGROUND: Self expandable metallic stents (SEMS) are effective in the palliation of malignant airway obstruction. Tumor in-growth, however, frequently occurs because of a shortage of effective local therapy. Additionally, SEMS are frequently associated with problems of fracture, migration, and difficult removals. Our goal was to develop a novel bioabsorbable ...
Thiamwong Ladda - - 2013
To develop a model of healthy aging from the perspective of Thais, a grounded theory approach, including in-depth interviews and focus groups, was used. A purposive sample of 39 community-dwelling adults aged 40-85 years old was interviewed. The Thai healthy aging model composed of three themes: normality, nature, and dharma. ...
Peters Jane - - 2013
Social support has been associated with positive outcomes regarding the mothering experience, and professional interventions have therefore been developed in formal settings to promote this. An ethnographic approach was used to consider the subjective experiences of mothers attending a professionally-facilitated group for parents and children aged 0-4 years, focusing on ...
Green Jonathan A - - 2013
The field metabolic rate (FMR) of a free-ranging animal can be considered as the sum of its maintenance costs (minimum metabolic rate; MMR), and additional costs associated with thermoregulation, digestion, production and activity. However, the relationships between these two quantities and how they relate to behaviour and extrinsic influences is ...
Lee Guan-Huei - - 2013
OBJECTIVE: Few cases of primary entecavir resistance in chronic hepatitis B patients have been reported to date. The serial profiling of the HBV polymerase gene mutations from a treatment-naive patient who developed drug resistance after 32 months of entecavir therapy is presented here. DESIGN: Serum samples were collected at multiple time ...
Shiota Takaya - - 2013
The oscillation of a polymer gel induced by the Belousov-Zhabotinsky (BZ) reaction was investigated under an external force composed of a square wave. The oscillation of the BZ reaction entrained to the periodic force, and the features of this entrainment changed depending on the period and duty cycle of the ...
Miao Chunhui - - 2013
In this work, a higher concentration of Ti ions are incorporated into hydrothermally grown Ti-doped (2.2% by atomic ratio) micro-nano-structured hematite films by an in situ solid-state reaction method. The doping concentration is improved from 2.2 % to 19.7 % after the in situ solid-state reaction. X-ray absorption analysis indicates ...
Millett Peter J - - 2013
BACKGROUND:Bony deficiency of the anteroinferior glenoid rim can cause recurrent glenohumeral instability. To address this problem, bony reconstruction is recommended in patients with glenoid bone loss more than 20% to 25%. Recent advances in shoulder surgery techniques allow for the arthroscopic reconstruction of glenoid bone defects to restore stability. HYPOTHESIS:The ...
White James D - - 2013
The acetylcholinesterase inhibitor (-)-huperzine A was synthesized from (S)-4-hydroxycyclohex-2-enone in 17 steps by a route that involved two cyclobutane fragmentations. The first of these employed a retro-aldol cleavage to generate the α-pyridone ring of huperzine A, and the second invoked a novel intramolecular aza-Prins reaction in tandem with stereocontrolled scission ...
Butterfield B J - - 2013
Biotic interactions can shape phylogenetic community structure (PCS). However, we do not know how the asymmetric effects of foundation species on communities extend to effects on PCS. We assessed PCS of alpine plant communities around the world, both within cushion plant foundation species and adjacent open ground, and compared the ...
Manet Sabine - - 2013
The effect of counterions was investigated to probe the principal ionic effects on the solubility in water and melting behavior of cationic gemini surfactants. We focused on two types of counterions: (1) small and inorganic counterions which are typically taken from the Hofmeister series were studied to focus on the ...
Berlim Marcelo T - - 2013
Clinical trials comparing the efficacy and acceptability of high frequency repetitive transcranial magnetic stimulation (HF-rTMS) and electroconvulsive therapy (ECT) for treating major depression (MD) have yielded conflicting results. As this may have been the result of limited statistical power, we have carried out this meta-analysis to examine this issue. We searched the ...
Leibovitz Zvi - - 2013
OBJECTIVE: To examine the feasibility of ultrasonographic imaging of foetal tympanic rings (TR). METHODS: An observational cohort study of eighty healthy foetuses of low-risk pregnancies divided into four gestational age subgroups (12(th) week, 16(th) week, 23(rd) week, and 32(nd) week) was performed. Each subgroup comprised twenty sequential foetal sonographic examinations. ...
Chiueh Tzong-Shi - - 2013
We collected and analyzed the time to detection (TTD) of blood cultures in the BacT/Alert automated system from 2002 to 2007. Among the 10,893 monomicrobial isolates from a total of 133,735 blood culture sets, the recoveries of aerobic bottles were compared with those of anaerobic bottles in this study. Significantly ...
Jena Amarnath - - 2013
PURPOSE: To assess the effects of reduced scan time in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast for the evaluation of pharmacokinetic parameters (K(trans) , v(e) , and k(ep) ). MATERIALS AND METHODS: High temporal resolution DCE-MRI was performed for calculation of pharmacokinetic parameters (K(trans) , v(e) , and ...
Robinson John A - - 2013
This review highlights the growing importance of protein epitope mimetics in the discovery of new biologically active molecules and their potential applications in drug and vaccine research. The focus is on folded β-hairpin mimetics, which are designed to mimic β-hairpin motifs in biologically important peptides and proteins. An ever-growing number ...
Bell Sue Anne - - 2013
In this cross-sectional study, the strengths, challenges and current status of baccalaureate nursing education in Ghana were described using a descriptive design. The World Health Organization Global Standards for the Initial Education of Nurses and Midwives were used as the organizing framework, with baseline data on the status of nursing ...
Buckley Thomas - - 2013
AIMS AND OBJECTIVES: To explore which medications Australian nurse practitioners most frequently prescribe. BACKGROUND: Although nurse practitioners in Australia have prescriptive authority, little is known about which specific medications nurse practitioners are prescribing and how frequently they do so. DESIGN: Descriptive electronic survey. METHODS: A total of 209 nurse practitioners ...
Prowse Thomas A A - - 2013
Population viability analysis (PVA) is widely used to assess the extinction risk of threatened species and to evaluate different management strategies. However, conventional PVA neglects important biotic interactions and therefore can fail to identify important threatening processes. We designed a new PVA approach that includes species interactions explicitly by networking ...
Galichon Pierre - - 2013
Renal transplantation is the best option for patients with end-stage renal disease (ESRD), but its half-life is limited to a decade. Clinical and histological markers measurable within the first year of transplantation can be used to predict its outcome. These markers are important for selecting kidneys for transplantation, for identifying ...
Dodson Julian J - - 2013
Extensive individual variation in spatial behaviour is a common feature among species that exhibit migratory life cycles. Nowhere is this more evident than in salmonid fishes; individual fish may complete their entire life cycle in freshwater streams, others may migrate variable distances at sea and yet others limit their migrations ...
Janzen Claude Jennifer Amy - - 2013
Health anxiety has been infrequently examined in individuals with diabetes. In this study, individuals with Type 1 or 2 diabetes (n = 414) completed questionnaires assessing health anxiety and related constructs. Elevated health anxiety was reported by 24.1 percent of the sample and was greater among younger individuals, females, unmarried ...
Ratliff Brian B - - 2013
The list of signals sent by an injured organ to systemic circulation, so-called danger signals, is growing to include multiple metabolites and secreted moieties, thus revealing a highly complex and integrated network of interlinked systemic proinflammatory and proregenerative messages. Emerging new data indicate that, apart from the well established local ...
Ruamps Renaud Hadrien - - 2013
This paper reports the experimental and theoretical investigations of two trigonal bipyramidal Ni(II) complexes, the [Ni(Me6tren)Cl](ClO4) 1 and [Ni(Me6tren)Br](Br) 2. High Field, High frequency Electron Paramagnetic Resonance spectroscopy performed on a single crystal of the [Ni(Me6tren)Cl](ClO4) 1 shows a giant uniaxial magnetic anisotropy with an experimental Dexp value (energy difference ...
Rojas M E - - 2013
Piscirickettsia salmonis is the aetiological agent of piscirickettsiosis, a disease which affects a variety of teleost species and that is particularly severe in salmonid fish. Bacterial-free supernatants, obtained from cultures of three isolates of Piscirickettsia salmonis, were inoculated in Atlantic salmon, Salmo salar L., and in three continuous cell lines ...
Ehizibolo D O - - 2013
The epidemiological situation of foot-and-mouth disease virus (FMDV) is uncertain in Nigeria, where the disease is endemic, and the majority of outbreaks are unreported. Control measures for FMD in Nigeria are not being implemented due to the absence of locally produced vaccines and an official ban on vaccine importation. This ...
Ruano Rodrigo - - 2013
OBJECTIVE: To evaluate the effect of early fetoscopic tracheal occlusion (22-24 weeks) on pulmonary response and neonatal survival in extremely severe isolated CDH. METHODS: Multicenter study involving fetuses with extremely severe CDH (lung-to-head ratio <0.70, liver herniation into the thoracic cavity, no other detectable anomalies). Between August 2010 and December ...
Pfaff Tamara - - 2013
This study was designed to determine the effects of Compound A on spermatogenesis including assessment of inhibin B levels and on fertility in the male rat over a 15 to 19 weeks treatment and a 19 weeks treatment-free period in control and 30, 60, and 180 mg/kg dose groups (n = ...
Hess Ursula - - 2013
Emotional mimicry is the imitation of the emotional expressions of others. According to the classic view on emotional mimicry (the Matched Motor Hypothesis), people mimic the specific facial movements that comprise a discrete emotional expression. However, little evidence exists for the mimicry of discrete emotions; rather, the extant evidence supports ...
Jennette J Charles - - 2013
Clinical, in vitro, and experimental animal observations indicate that antineutrophil cytoplasmic autoantibodies (ANCA) are pathogenic. The genesis of the ANCA autoimmune response is a multifactorial process that includes genetic predisposition, environmental adjuvant factors, an initiating antigen, and failure of T cell regulation. ANCA activate primed neutrophils (and monocytes) by binding ...
Swartz Timothy D - - 2013
The gut microbiota is implicated in host metabolism and energy regulation. Germ-free (GF) C57BL/6 mice display decreased adiposity, an effect associated with increased intestinal fasting-induced adipose factor (FIAF) and decreased hepatic lipogenesis. However, whether the altered metabolism observed in the absence of gut microbiota extends to other species, commonly used ...
Fessart Delphine - - 2013
In the present study, we have developed an in vitro three-dimensional (3D) model to differentiate normal from lung cancer cells in order to study the mechanisms resulting in lung cancer.Using a reconstituted laminin-rich basement membrane (Matrigel), we were able to culture normal human bronchial epithelial cells (HBEC) and a subset ...
Ziv Margalit - - 2013
Emotion understanding and theory of mind (ToM) are two major aspects of social cognition in which deaf children demonstrate developmental delays. The current study investigated these social cognition aspects in two subgroups of deaf children-those with cochlear implants who communicate orally (speakers) and those who communicate primarily using sign language ...
Siddiqui Ruqaiyyah - - 2013
The opportunist free-living protists such as Acanthamoeba spp. and Balamuthia mandrillaris have become a serious threat to human life. As most available drugs target functional aspects of pathogens, the ability of free-living protists to transform into metabolically inactive cyst forms presents a challenge in treatment. It is hoped, that the ...
Gentric J C - - 2013
BACKGROUND AND PURPOSE:Endovascular embolization of wide-neck intracranial aneurysms can be technically challenging, especially when the anatomy is complex. Stent reconstruction of the parent artery is commonly used to treat wide-neck and bifurcated aneurysms. The main objective of this study was to investigate the periprocedural and midterm morbidity and mortality results ...
Keough James M - - 2013
In photosynthetic oxygen evolution, redox active tyrosine Z (YZ) plays an essential role in proton-coupled electron transfer (PCET) reactions. Four sequential photooxidation reactions are necessary to produce oxygen at a Mn(4)CaO(5) cluster. The sequentially oxidized states of this oxygen-evolving cluster (OEC) are called the S(n) states, where n refers to ...
Torii Hideto - - 2013
Ralstonia pickettii DTP0602 utilizes 2,4,6-trichlorophenol (2,4,6-TCP) as its sole source of carbon. The expression of catabolic pathway genes (hadA, hadB and hadC) for 2,4,6-TCP has been reported to be regulated by the LysR-type transcriptional regulator (LTTR), HadR. Generally, coinducers are recognized as being important for the function of LTTRs, and ...
Manzano Francisco - - 2013
AIM: To compare the effectiveness of alternating pressure air mattresses vs. overlays to prevent pressure ulcers in mechanically ventilated patients in intensive care units. BACKGROUND: Pressure ulcers prevention is an important issue in the nursing of critically ill patients. It is not clear whether alternating pressure air mattresses are more ...
Oskoui Maryam - - 2013
AIMS: The aim of this study was to provide a comprehensive update on (1) the overall prevalence of cerebral palsy (CP); (2) the prevalence of CP in relation to birthweight; and (3) the prevalence of CP in relation to gestational age. METHOD: A systematic review and meta-analysis was conducted and ...
Preece Daniel - - 2013
Three-dimensional (3D) information plays an important part in medical and veterinary education. Appreciating complex 3D spatial relationships requires a strong foundational understanding of anatomy and mental 3D visualization skills. Novel learning resources have been introduced to anatomy training to achieve this. Objective evaluation of their comparative efficacies remains scarce in ...
Tai Alexander X - - 2013
Prior studies have identified two anatomically and neurochemically distinct cellular compartments within the mammalian striatum, termed striosomes and matrix, which express μ-opioid receptors (μOR) and EphA4, respectively. Here we identify and characterize an additional compartment in the rat striatum composed of neurons that express EphA7. In situ hybridization and immunohistochemical ...
Millischer Ae - - 2013
OBJECTIVE: To evaluate if a standard complete anatomical fetal survey, as recommended based on ultrasound (US) examination guidelines was feasible using a standardized MRI protocol. METHODS: Based on guidelines for US-based examination, we built up a specific MRI protocol for fetal anatomical survey. This protocol was then prospectively tested in ...
< 4 5 6 7 8 9 10 11 12 13 14 >