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Ma Dik-Lung - - 2013
Breakthrough advances in chemistry and biology over the last two decades have vastly expanded the repertoire of nucleic acid structure and function with potential application in multiple areas of science and technology, including sensing and analytical applications. DNA oligonucleotides represent popular tools for the development of sensing platforms due to ...
Yamanaka Iori - - 2013
Synaptic transmission-dependent regulation of neurotransmitter receptor accumulation at postsynaptic sites underlies the formation, maintenance and maturation of synaptic function. Previous in vitro studies showed that glycine receptor (GlyR) clustering requires synaptic inputs. However, in vivo GlyR regulation by synaptic transmission is not fully understood. Here, we established a model system ...
Leyssen W - - 2013
Aims To investigate the working patterns and patient base of registered clinical dental technicians (CDTs); their relationships with dentists and other professionals in the dental team; their willingness to work within the NHS and their expectations for the future as a new professional group.Methods Face-to-face qualitative interviews of registered CDTs, ...
Poulsen Keith P - - 2013
Listeria monocytogenes causes several clinical manifestations in humans and domestic animals. This bacterium is a saprophyte in soil and ensiled feeds, which are sources of infection for food producing animals (i.e. ruminants). The most common route of infection for people is via ingestion of contaminated ready-to-eat food products such as ...
Li Liang - - 2013
In this paper, a C-F bond activation reaction of a chloro-bridged iridium(iii) dimer (dfppy)(2)Ir(μ-Cl)(2)Ir(dfppy)(2) () (dfppy denotes 2-(4,6-difluorophenyl)pyridyl) in the presence of sodium methoxide has been reported, leading to the formation of a heteroleptic cyclometalated iridium(iii) fluorophenylpyridine complex . HPLC-mass analysis confirmed the release of formaldehyde in the product mixture. ...
Rosty Christophe - - 2013
KRAS-mutated carcinomas comprise 35-40% of all colorectal carcinomas but little is known about their characteristics. The aim of this study was to examine the pathological and molecular features of KRAS-mutated colorectal carcinomas and to compare them with other carcinoma subgroups. KRAS mutation testing was performed in 776 incident tumors from ...
Ahmadi Omid - - 2013
BACKGROUND: Immunosenescence may contribute to an observed increase in infections and specific cancers in the elderly. Lymph nodes play a key role in the body's immune system. A systematic review was undertaken to investigate the effects of senescence on lymph node number and morphology. METHODS: Electronic databases Ovid MEDLINE, Embase ...
Baumgardt J A - - 2013
Population sex ratio is an important metric for wildlife management and conservation, but estimates can be difficult to obtain, particularly for sexually monomorphic species or for species that differ in detection probability between the sexes. Noninvasive genetic sampling (NGS) using polymerase chain reaction (PCR) has become a common method for ...
Kim B J - - 2013
BACKGROUND: Exposure to ambient air pollution and bronchiolitis are risk factors for asthma. The aim of this study was to investigate the effect of air pollution on the development of asthma in children with past episodes of bronchiolitis. METHODS: A prospective 2-year follow-up survey consisting of parental responses to the ...
Fusco Nicola - - 2013
The assessment of human epidermal growth factor receptor 2 (HER2) status in gastric cancer is crucial in selecting patients who may benefit from targeted therapy, yet heterogeneous expression could represent an important drawback for HER2 testing. We aimed to analyze (i) HER2 heterogeneity in primary gastric cancers, pre-neoplastic and metastatic ...
Lambert-Humble Stephen - - 2013
Objective To explore patients' motivations and expectations for dental implants.Design Single-setting, qualitative interview study.Subjects, setting and method Semi-structured, telephone interviews were conducted with nine patients who had consulted a restorative dental practitioner with an interest in implantology about the possibility of replacing their missing teeth with dental implants.Outcome measure Interview ...
Fu Da-Wei - - 2013
Molecular ferroelectrics are highly desirable for their easy and environmentally friendly processing, light weight, and mechanical flexibility. We found that diisopropylammonium bromide (DIPAB), a molecular crystal processed from aqueous solution, is a ferroelectric with a spontaneous polarization of 23 microcoulombs per square centimeter [close to that of barium titanate (BTO)], ...
Huang Y - - 2013
Coproantigen test kits for Echinococcus spp. worms in dogs, designed for commercial use, were obtained from three different Chinese producers, and were compared with a laboratory kit using reagents from New Zealand. None of the three producers would provide details of their test validation. From a known set of dog ...
Perry Rebecca - - 2013
Recently it has been demonstrated that high resolution transthoracic echocardiography (HRTTE) is able to detect differences in the wall thickness of the left anterior descending coronary artery (LAD) between patients with coronary artery disease (CAD) and normal volunteers. We sought to validate this technique, develop a normal range of values ...
Lehti Timo A - - 2013
Heterogeneity of cell population is a key component behind the evolutionary success of Escherichia coli. The heterogeneity supports species adaptation and mainly results from lateral gene transfer. Adaptation may also involve genomic alterations that affect regulation of conserved genes. Here we analyzed regulation of the mat (or ecp) genes that ...
Martínez-Montero P - - 2013
Introduction. Pelizaeus-Merzbacher disease (PMD) is caused in most cases by either duplications or point mutations in the PLP1 gene. This disease, a dysmyelinating disorder affecting mainly the central nervous system, has a wide clinical spectrum and its causing mutations act through different molecular mechanisms. Methods. Eighty-eight male patients with leukodystrophy ...
Dewar Meagan L - - 2013
Despite the enormous amount of data available on the importance of the gastrointestinal (GI) microbiota in vertebrate (especially mammals), information on the GI microbiota of seabirds remains incomplete. As with many seabirds, penguins have a unique digestive physiology that enables them to store large reserves of adipose tissue, protein, and ...
Bura Thomas - - 2013
New Ir(iii) complexes involving N,C-chelating difluorophenyl-pyridine (dfppy) or dibenzo[a,c]phenazine (dbpz) ligands along with either N,N-bound 5-ethynyl-2,2'-bipyridine (e-bpy) or CO + Cl co-ligands have been obtained as [Ir(dfppy)(2)(e-bpy)]PF(6), [Ir(dbpz)(2)(e-bpy)]PF(6) and cis-[Ir(dbpz)(2)(Cl)(CO)]. A single-crystal X-ray diffraction study of cis-[Ir(dbpz)(2)(CO)Cl] has shown the Ir(iii) centre to adopt a distorted octahedral coordination geometry with ...
Rolim Filho St - - 2013
The osteopontin gene may influence the fertility of water buffaloes because it is a protein present in sperm. The aim of this work was to identify polymorphisms in this gene and associate them with fertility parameters of animals kept under extensive grazing. A total of 306 male buffaloes older than ...
Iranmanesh Pouya - - 2013
BACKGROUND: Strategies to spare operating room (OR) times are crucial to limiting the costs involved in robotic surgery. Among other factors, the pre-operative set-up and docking phases have been incriminated at first to be time consuming. The docking process on the standard multiport da Vinci Surgical System has not been ...
Chen Derrick - - 2013
Carcinoma cuniculatum, a unique variant of well-differentiated squamous cell carcinoma, has been only rarely reported in the esophagus. The present study was undertaken to determine if a previously observed common histologic pattern for carcinoma cuniculatum is diagnostically useful in esophageal mucosal biopsy specimens. Thirty-five esophageal mucosal biopsies obtained from 25 ...
Byun Ju-Young - - 2013
The C-reactive protein (CRP), which has a five repeat pentameric structure, is known to be a marker for acute inflammation and a potential risk predictor for cardiovascular disease. A simple and rapid homogeneous assay method for the detection of CRP, based on a gold nanoparticle (AuNP) aggregation induced colorimetric response, ...
Holland Kathlyn Elena - - 2013
This study aimed to explore how novice occupational therapists conceptualized professional confidence. Professional confidence is a dynamic personal belief that matures over time. It is closely linked to both competence and professional identity ensuring fitness for practice. Although professional confidence has been defined and a number of its attributes have ...
de Sá Arsénio - - 2013
Due to its favorable relaxometric properties, Mn(2+) is an appealing metal ion for magnetic resonance imaging (MRI) contrast agents. This paper reports the synthesis and characterization of three new triazadicarboxylate-type ligands and their Mn(2+) chelates (, 1,4,7-triazacyclononane-1,4-diacetate-7-heptanil; , 1,4,7-triazacyclononane-1,4-diacetate-7-benzoic acid; and , 1,4,7-triazacyclononane-1,4-diacetate-7-hexanoic acid). The protonation constants of the ligands ...
Baroux Noémie - - 2013
AIM: Despite the well-documented burden of rheumatic heart disease (RHD) in several Pacific countries, the disease is poorly understood in New Caledonia. The aim of this study was to assess the prevalence of RHD detected by echocardiographic screening in school children. METHODS: An annual RHD screening programme is conducted by ...
Schmid Thibault E - - 2013
A series of N-heterocyclic carbene (NHC)/PR(3) palladium(ii) and palladium(0) complexes has been synthesized and fully characterized. X-ray crystallographic data have allowed comparison of ligand steric properties. The NHC ligand was found to vary its steric properties as a function of the phosphine co-ligand. These complexes display interesting catalytic properties in ...
Iwasaki Yukiko - - 2013
Interleukin-27 (IL-27) suppresses immune responses through inhibition of the development of IL-17 producing T-helper (Th) 17 cells and induction of IL-10 production. We previously showed that forced expression of early growth response gene 2 (Egr-2), a transcription factor required for T-cell anergy induction, induces IL-10 and lymphocyte activation gene 3 ...
Morimoto Shota - - 2013
A photo-switchable fluorescent flagging approach has been developed to identify photoaffinity-labeled peptides in target protein. Upon photochemical release of the ligand, the protein was newly modified with a coumarin in place of the previously attached biotin. It allowed us to simplify complex identification processes for labeled sites.
Bachoo I K - - 2013
As part of the continuing evolution towards conservative dentistry there has been a drive to push further and investigate the possibility of inducing the repair and regeneration of lost dental hard tissue. Until recently, the prospect of repair and regeneration had been confined to laboratory studies and hypothesised scientific models. ...
Plaçais Pierre-Yves - - 2013
The brain regulates energy homeostasis in the organism. Under resource shortage, the brain takes priority over peripheral organs for energy supply. But can the brain also down-regulate its own consumption to favor survival? We show that the brain of Drosophila specifically disables the costly formation of aversive long-term memory (LTM) ...
Gao Y - - 2013
BACKGROUND: During storage, red blood cells (RBCs) lose their membrane stability, leading to haemolysis and microparticle (MP) formation. The use of RBCs stored for more than 28 days has been associated with an increased incidence of deep vein thrombosis. However, the exact mechanism by which coagulation activation is enhanced in stored ...
Hodges P W - - 2013
BACKGROUND: Movement changes in pain. Unlike the somewhat stereotypical response of limb muscles to pain, trunk muscle responses are highly variable when challenged by pain in that region. This has led many to question the existence of a common underlying theory to explain the adaptation. Here, we tested the hypotheses ...
Vitasse Yann - - 2013
In a temperate climate, understory trees leaf out earlier than canopy trees, but the cause of this discrepancy remains unclear. This study aims to investigate whether this discrepancy results from ontogenic changes or from microclimatic differences. Seedlings of five deciduous tree species were grown in spring 2012 in the understory ...
Zhang Shi-Yuan - - 2013
An air-stable and water-tolerant ortho-metallated complex [Co(tfb)(bpy)(2)](NO(3))·3H(2)O was obtained via hydrothermal synthesis. The mechanism for the formation of Co-C bond was studied using both DFT calculations and experimental analysis. This highly stable complex exhibits good catalytic performance for the selective oxidation of cyclohexane.
Otani Hiroshi - - 2013
In bacteria, the RNA polymerase holoenzyme comprises a five-subunit core enzyme and a dissociable subunit, sigma factor, which is responsible for transcriptional initiation. The filamentous bacterium Streptomyces griseus has 52 sigma factors, including one essential "principal" sigma factor (σ(HrdB) ) that is responsible for the transcription of housekeeping genes. Here ...
Posada-Quintero H F - - 2013
This work presents the evaluation of pulse rate variability (PRV) obtained from pulse onsets of photoplethysmographic (PPG) signals. Three published algorithms were used to determine the pulse onsets: diastolic point, maximum second derivative and tangent intersection. Temporal series of pulse onsets were obtained for each method, and several variability indices ...
Zhao Xiang-Qian - - 2013
BACKGROUND: This study aims to compare the effects of two different local resection procedures on the prognosis of ampullary cancer. METHODS: We carried out a retrospective study using clinical and pathological data from patients with ampullary cancer who underwent local resection between February 1996 and February 2009 in the PLA ...
Bidon Tobias - - 2013
We report a new approach for molecular sex identification of extant Ursinae and Tremarctinae bears. Two Y-specific fragments (SMCY and 318.2) and one X-specific fragment (ZFX) are amplified in a multiplex PCR, yielding a double test for male-specific amplification and an internal positive control. The primers were designed and tested ...
Garmon Christopher - - 2013
This paper explores the impact of employer-provided health insurance on hospital competition and hospital mergers. Under employer-provided health insurance, employer executives act as agents for their employees in selecting health insurance options for their firm. The paper investigates whether a merger of hospitals favored by executives will result in a ...
Sanders Andrew - - 2013
BACKGROUND: Urosepsis is the most common complication requiring hospital admission after transrectal biopsy of the prostate. This study aims to assess the local incidence and causative organisms of hospital admissions with urosepsis after transrectal ultrasound-guided prostate (TRUS) biopsy. As morbidity is high, treatment must be commenced empirically prior to cultures. ...
Krysko O - - 2013
BACKGROUND: Staphylococcal enterotoxin B (SEB) is a superantigen known to be a modulator of chronic airway inflammation in mice and humans, yet little is known about the mechanisms that regulate its interaction with the innate immune system. We investigated this mechanism in a murine model of allergic airway inflammation induced ...
Chang G - - 2013
We aimed to determine whether a unique, ultra-high-field 7 T magnetic resonance imaging (MRI) scanner could detect occult cartilage and meniscal injuries in asymptomatic female dancers. This study had Institutional Review Board approval. We recruited eight pre-professional female dancers and nine non-athletic, female controls. We scanned the dominant knee on a ...
Zhang G - - 2013
BACKGROUND: Neonatal Bacillus Calmette-Guérin (BCG) vaccination induces vigorous T-helper type 1 (Th1) responses and inhibits allergy-related airway dysfunction, but the exact mechanisms remain unclear. The objective of this study was to address where the Th1 cells induced by neonatal BCG vaccination are generated and stored, and how they are recruited ...
Hemmati I - - 2013
During laser deposition of Ni-Cr-B-Si-C alloys with high amounts of Cr and B, various microstructures and phases can be generated from the same chemical composition that results in heterogeneous properties in the clad layer. In this study, the microstructure and phase constitution of a high-alloy Ni-Cr-B-Si-C coating deposited by laser ...
Van De Ven Monique O M - - 2013
Objective: The aim of this study was to investigate whether asthma predicts the development of nicotine dependence and unsuccessful smoking cessation attempts in adolescent smokers. In addition, it was tested whether nicotine dependence could explain the relation between asthma and unsuccessful cessation attempts. Methods: A longitudinal survey study was conducted ...
Calvo-Guirado José L - - 2013
OBJECTIVES: The aim of the present study was to evaluate bone-to-implant contact (BIC) and bone remodeling dynamics after immediate implant placement at different levels in relation to the crestal bone. MATERIALS AND METHODS: The mandibular second, third, and fourth premolars of six Foxhound dogs were extracted bilaterally. Randomly, three implants ...
Mazumdar Suman - - 2013
ABSTRACT: BACKGROUND: Due to its abundance and low-price, glycerol has become an attractive carbon source for the industrial production of value-added fuels and chemicals. This work reports the engineering of E. coli for the efficient conversion of glycerol into L-lactic acid (L-lactate). RESULTS: Escherichia coli strains have previously been metabolically ...
Du Feng - - 2013
A novel detection method for RNA pathogens based on one-step reverse transcription PCR is introduced here. This method utilized the reverse transcriptase activity and the 5'-nuclease activity of TaqM1 DNA polymerase to transform target RNA into cDNA. The following PCR process released a fragment from the 5' end as a ...
Watt R G - - 2013
This is the final paper in a series reporting on the results of the 2009 Adult Dental Health Survey. Since 1968 national adult surveys have been repeated every decade with broadly similar methods providing a unique overview of trends in oral health over a 40-year period. This paper aims to ...
Ivanova N - - 2013
Common-envelope events (CEEs), during which two stars temporarily orbit within a shared envelope, are believed to be vital for the formation of a wide range of close binaries. For decades, the only evidence that CEEs actually occur has been indirect, based on the existence of systems that could not be ...
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