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Xiao Yao - - 2013
Column experiments were conducted to investigate the transport of aqueous C60 (aqu-nC60), fullerol, silver nanoparticles (NPs) coated with polyvinylpyrrolidone (Ag-PVP) and stabilized by citrate (Ag-CIT) in biofilm-laden porous media. Gram-negative Pseudomonas aeruginosa (PA) and Gram-positive Bacillus cereus (BC) biofilm-laden glass beads were selected to represent the bacterial interfaces NPs might ...
Shaheen Ranad R Developmental Genetics Unit, King Faisal Specialist Hospital and Research Center, MBC-03 PO BOX 3354, Riyadh 11211, Saudi Arabia. - - 2013
Meckel-Gruber syndrome (MKS) is a genetically heterogeneous severe ciliopathy characterised by early lethality, occipital encephalocele, polydactyly, and polycystic kidney disease. To report genetic analysis results in two families in which all known MKS diseases genes have been excluded. In two consanguineous families with classical MKS in which autozygome-guided sequencing of ...
van Tuyl Lilian H D LH Department of Rheumatology, VU University Medical Center, , Amsterdam, The - - 2014
To evaluate the difference between chronological and random sequence reading in a series of radiographs with 11 years' follow-up. In addition, the influence of the starting point and length of series was evaluated. Two experienced readers independently and repeatedly scored digitised radiographs of 62 patients at time points 0, 2, ...
Kropat Christopher - - 2013
In a human pilot intervention study (healthy + ileostomy probands), the questions were addressed whether in vivo consumption of an anthocyanin-rich bilberry (Vaccinium myrtillius L.) pomace extract (BE) affects (i) the transcription of Nrf2-dependent genes in peripheral blood mononuclear cells (PBMC), indicative for systemic effects, and (ii) the level of ...
Stewart Jane - - 2013
BACKGROUND: Inhibin B was measured in plasma samples obtained from 34 healthy male subjects selected on criteria typical for a phase I clinical trial across a wide age range (19-70 years). METHODS: Mutiple samples (up to seven per subject) were obtained as a set consisting of one baseline sample then ...
Dias Sónia - - 2013
Migration has been associated with a greater vulnerability in health. Migrants, especially women, go through several experiences during the migration process and in the host countries that ultimately put their health at risk. This study examines self-reported health status and preventive behaviors among female and male immigrants in Portugal, and ...
Martínez Francisca - - 2013
Abstract Improvements in early diagnosis and treatment strategies in cancer patients have enabled younger women with cancer to survive. In addition to the stressful event of the diagnosis, patients with malignant diseases face the potential loss of the opportunity to have children. Preservation of fertility has become a challenging issue ...
Gresenz Carole Roan - - 2013
OBJECTIVE: To provide a conceptual framework and to assess the availability of empirical data for supply-side microsimulation modeling in the context of health care. DATA SOURCES: Multiple secondary data sources, including the American Community Survey, Health Tracking Physician Survey, and SK&A physician database. STUDY DESIGN: We apply our conceptual framework ...
Filipiak Piotr - - 2013
Nanosecond laser flash photolysis was used to generate sulfur radical cations of the thioether, S-methylglutathione (S-Me-Glu), via the one-electron oxidation of this thioether by triplet 4-carboxybenzophenone. The purpose of this investigation was to follow the neighboring group effects resulting from the interactions between the sulfur radical cationic sites and nearby ...
Findsen Anders - - 2013
Chill tolerance of insects is defined as the ability of insects to tolerate low temperature under circumstances not involving freezing of intra- or extracellular fluids. For many insects chill tolerance is crucial for their ability to persist in cold environments and mounting evidence indicate that chill tolerance is associated with ...
Blasio Angelo - - 2013
Binge eating disorder is an addiction-like disorder characterized by excessive food consumption within discrete periods of time. This study was aimed at understanding the role of the opioid system within the medial prefrontal cortex (mPFC) in the consummatory and motivational aspects of binge-like eating. For this purpose, we trained male ...
Grace Miriam M School of Engineering and Science, Jacobs University Bremen, Bremen 28759, Germany. - - 2013
In many biological systems, variability of the components can be expected to outrank statistical fluctuations in the shaping of self-organized patterns. In pioneering work in the late 1990s, it was hypothesized that a drift of cellular parameters (along a 'developmental path'), together with differences in cell properties ('desynchronization' of cells ...
Villars Hélène - - 2013
BACKGROUND: Emergency room (ER) re-hospitalizations are prevalent in severe Alzheimer's disease affected older patients. DESIGN: Quasi-experimental before and after study. SETTING: Discharge of severely demented patients from a Special Alzheimer Acute Care Unit. PARTICIPANTS: A total of 390 patients hospitalized in the unit from 2007 through 2009, with at least ...
Cameron Sharon T - - 2013
BACKGROUND: Bladder distension is thought to cause the uterine axis to become more aligned with the cervical canal. Among women undergoing assisted conception it has been demonstrated that having a full bladder facilitates the passage of an intrauterine catheter for embryo transfer. OBJECTIVE: To determine if insertion of intrauterine contraceptive ...
Wheaton Felicia V FV Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089-0191, USA. - - 2013
This study examines sex differences in the association between migration and exposure to an urban environment and overweight, hypertension and diabetes in later life. Interviews were conducted with 3,604 adults aged 50 and older in the Mexican Family Life Survey (MxFLS). Logistic regression analyses were used to examine the association ...
Owusu James A - - 2013
ObjectiveTo determine national variations in resource utilization for primary repair of cleft lip, identify patient and institutional factors associated with high resource use, and estimate the current incidence of cleft lip in the United States.Study DesignRetrospective analysis of a national, pediatric database (2009 Kids' Inpatient Database [KID]).MethodsPatients aged 1 year ...
Barry Heather E - - 2013
OBJECTIVES: To explore community pharmacists' experiences with and attitudes towards people with dementia, and to determine the knowledge they have about pain and its management in this patient population. METHODS: A questionnaire comprising five sections, including the Approaches to Dementia Questionnaire, was mailed, on two occasions, during February and March ...
Naismith G D - - 2013
BACKGROUND: As a non-invasive marker of gastrointestinal inflammation, faecal calprotectin (FC) is being increasingly used to guide the management of Crohn's disease. It is therefore a concern that studies have shown variability in day to day levels. AIM: To determine the degree of this intrapersonal variability in the context of ...
Abrahams Yoonus - - 2013
COL5A1 encodes for the α1 chain of type V collagen, an important regulator of fibril assembly in tendons, ligaments and other connective tissues. A polymorphism (rs12722) within the functional COL5A1 3'-untranslated region (UTR) has been shown to associate with chronic Achilles tendinopathy and other exercise-related phenotypes. The COL5A1 3'-UTR contains ...
Lasaponara Fedele - - 2013
INTRODUCTION.: The phosphodiesterase type 5 (PDE5) inhibitors are generally well tolerated and effective for treating erectile dysfunction (ED), including in patients with significant comorbidity. Because of this benign safety profile, investigators have used PDE5 inhibitors to treat patients with ED and severe renal disease or those who have received renal ...
Saggar Jasdeep K - - 2013
Poor distribution of anticancer drugs within solid tumors may limit their effectiveness. Here we characterize the distribution within solid tumors of biomarkers of drug effect. γH2aX, cleaved-caspase -3 or -6 and Ki-67 were quantified in tumor sections in relation to blood vessels (recognized by CD31) using monoclonal antibodies and immunohistochemistry. ...
Menning Sebastian - - 2013
Influencing the communication within a conjugated system as diphenylacetylene is a challenging subject in molecular electronics. Some examples of twisted tolanes are known where high torsions are achieved in the solid state by steric encumbrance. The insertion of a spacer system is an alternative way to tailor rotation. Only few ...
Nollet Kenneth E - - 2013
BACKGROUND: Microparticles in blood components might contribute to transfusion-related immunomodulation or other side effects. To elucidate the role of leukofiltration, we compared three commercially available filters for their effect on platelet (PLT)-derived (PDMP), leukocyte-derived (LDMP), and red blood cell-derived (RDMP) microparticle formation in apheresis PLTs. STUDY DESIGN AND METHODS: Apheresis ...
Chae Hee Young - - 2013
Glucagon-like peptide-1 (GLP-1) stimulates cell proliferation and has anti-apoptotic effects on pancreatic islet β cells. In our previous study, the transduction of mouse islets with a recombinant adenovirus containing GLP-1 cDNA enhanced islet graft survival. In this study, we sought to deliver the GLP-1 gene using a nonviral vector, which ...
Gellersen Birgit - - 2013
We have previously shown that the presence of trophoblast cells enhances invasiveness of decidualizing human endometrial stromal cells. The metastasis suppressor CD82, which has anti-migratory function in tumor cells, is up-regulated in decidualizing endometrial stromal cells. CEACAM1 is expressed in trophoblast cells at the invasion front in early placenta and ...
Nelson Barnaby - - 2013
AIM: Research in the phenomenological tradition suggests that the schizophrenia spectrum is characterized by disturbance of the 'basic' self, whereas borderline personality disorder involves disturbance of the 'narrative' self. The current study investigated this proposal in an ultra-high risk for psychosis sample. METHODS: The sample consisted of 42 ultra-high-risk participants ...
Ansah John P - - 2013
OBJECTIVE: To understand the effect of current and future long-term care (LTC) policies on family eldercare hours for older adults (60 years of age and older) in Singapore. DATA SOURCES: The Social Isolation Health and Lifestyles Survey, the Survey on Informal Caregiving, and the Singapore Government's Ministry of Health and Department ...
Huang Shih-Han S - - 2013
Owing to the drug's favorable hydrophilic and pharmacokinetic characteristics, a number of case reports have demonstrated effective treatment of atenolol overdose with hemodialysis. However, the efficiency of atenolol clearance throughout hemodialysis treatments has not previously been examined. In this report, a patient with impaired renal function was successfully treated with ...
Saugstad Ola Didrik - - 2013
AIM: To study the impact that using antenatal steroid to treat threatened preterm delivery has on whole genome expression. METHODS: A prospective whole genome expression study was carried out on 50 newborn infants, delivered before 32 weeks gestation, who had been exposed to antenatal steroids, including 40 who had received ...
Fang Xue-Qian - - 2013
Piezoelectric nano-structures have been regarded as the next-generation piezoelectric material due to their inherent nano-sized piezoelectricity. This review summarizes the recent theoretical and experimental findings in piezoelectric nano-structures, including piezoelectric nanowires, nanoplates, nanobeams, nanofilms, nanoparticles, and piezoelectric heterogeneous materials containing piezoelectric nano-inhomogeneities. To begin, the types of piezoelectric nano-structured materials ...
Mukherjee Krishnendu - - 2013
Listeria monocytogenes the causative agent of the foodborne disease listeriosis in humans often involves fatal brainstem infections leading to meningitis and meningoencephalitis. We recently established the larvae of the greater wax moth (Galleria mellonella) as a model host for the investigation of L. monocytogenes pathogenesis and as a source of ...
Herlihy Erin P - - 2013
IMPORTANCE Esotropia greater at distance than at near can be related to abducens palsy or to divergence insufficiency. Mild abduction weakness can be difficult to detect, blurring the distinction between these 2 conditions. OBJECTIVES To examine the clinical and eye movement findings that distinguish abducens palsy from divergence insufficiency and ...
Mandl József - - 2013
Endoplasmic reticulum (ER) stress is a regulatory mechanism that allows cells to adapt to a series of metabolic, redox, and other environmental changes. The role of ER stress was first identified in the maintenance of proteostasis. It has since been shown that ER stress is also critical to the regulation ...
Whaley Jonathan T - - 2013
ABSTRACT: OBJECTIVE: Proton therapy can result in clinically significant radiation dermatitis. In some clinical scenarios, such as lung or breast cancer, the risk of severe radiation dermatitis may limit beam arrangement and prescription doses. Patients undergoing proton therapy for prostate cancer commonly develop mild radiation dermatitis. Herein, we report the ...
Aversa Antonio - - 2013
INTRODUCTION: Weight loss in sexually active women improves their quality of life. At present, no studies have investigated whether weight loss may affect female sexual function in severe obese women. AIM: The aim of this study was to investigate the effects of different programs of weight loss on female sexual ...
Ladd Jennifer M - - 2013
Many professional societies and research studies recommend complete vaccination before pediatric solid organ transplantation. Nevertheless, incompletely vaccinated children often receive transplants. As the number of parents refusing to vaccinate children for nonmedical reasons increases, pediatric transplantation programs face difficult listing decisions. Given the importance of psychosocial criteria in listing decisions, ...
Maione Luigi - - 2013
Context:Kallmann syndrome (KS) is characterized by congenital hypogonadotropic hypogonadism (CHH) and an impaired sense of smell related to defective development of the olfactory system.Objective:The aim of the study was to use high-resolution computed tomography (CT) to detect specific abnormalities in the ethmoid bone region surrounding the olfactory bulbs in patients ...
Cleary Michelle - - 2013
AIMS AND OBJECTIVES: To explore recent Singapore nursing graduates' experience of and views about their career development and progress. BACKGROUND: The recruitment and retention of an adequate number of registered nurses is a continuing workforce issue in Singapore and other major cities. DESIGN: Survey of recent nursing graduates. METHODS: Recent ...
Provvidenza Christine - - 2013
OBJECTIVE: To: (1) provide a review of knowledge transfer (KT) and related concepts; (2) look at the impact of traditional and emerging KT strategies on concussion knowledge and education; (3) discuss the value and impact of KT to organisations and concussion-related decision making and (4) make recommendations for the future ...
Rai Dheeraj - - 2013
BACKGROUND: The prevalence and correlates of depression vary across countries. Contextual factors such as country-level income or income inequalities have been hypothesised to contribute to these differences. AIMS: To investigate associations of depression with socioeconomic factors at the country level (income inequality, gross national income) and individual (education, employment, assets ...
Zhang Min - - 2013
In randomized clinical trials, for example, on cancer patients, it is not uncommon that patients may voluntarily initiate a secondary treatment postrandomization, which needs to be properly adjusted for in estimating the "true" effects of randomized treatments. As an alternative to the approach based on a marginal structural Cox model ...
Mucaki Eliseos J - - 2013
Mutations that affect mRNA splicing often produce multiple mRNA isoforms, resulting in complex molecular phenotypes. Definition of an exon and its inclusion in mature mRNA relies on joint recognition of both acceptor and donor splice sites. This study predicts cryptic and exon skipping isoforms in mRNA produced by splicing mutations ...
Agius Ronald - - 2013
The performance of the previously validated LUCIO®-Direct-enzyme linked immunosorbent assay (direct ELISA) screening tests according to forensic guidelines is compared to that of cloned enzyme donor immunoassays (CEDIA) test for drugs of abuse in urine as defined in the new re-licensing German medical and psychological assessment (MPA) guidelines. The MPA ...
Dalbeth Nicola N Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, , Auckland, New - - 2013
SLC2A9 is a strong genetic risk factor for hyperuricaemia and gout. SLC2A9 (GLUT9) is a high capacity urate transporter and reportedly transports glucose and fructose. Intake of fructose-containing beverages is associated with development of hyperuricaemia and gout. To determine whether genetic variation in SLC2A9 influences the acute serum urate response ...
Pathan Meerakhan - - 2013
Ultrafast (UF) 2D NMR is a very promising methodology enabling the acquisition of 2D spectra in a single scan. In the last few years, the analytical performance of UF 2D NMR has been highly increased, consequently maximizing its range of applications. However, its implementation and use by non-specialists are far ...
Zhang Zifei - - 2013
Two ligands with different geometries have been prepared to synthesize new silver-ethynide complexes bearing pyridyl and carboxylate groups. Reactions of 5-ethynylnicotinic acid () and 5-ethynylpicolinic acid () with silver nitrate afforded [Ag(2)()·AgNO(3)](n) () and {[Ag(12)()(6)·12AgNO(3)]·5H(2)O}(n) (), respectively. Crystallographic studies revealed that in , the ligands connect linear silver chains to ...
Wang Nian N Department of Physics and Center for Biomedical Research, Oakland University, Rochester, Michigan 48309, - - 2013
To study the anisotropic characteristics of both multi-component T2 and T1ρ relaxation times in tendon. T2 and T1ρ were measured in tendon by NMR spectroscopy at different orientations and by microscopic MRI at the magic angle. Several experimental issues in the multi-component relaxation measurements were investigated, including the effects of ...
Wedemeyer Heiner - - 2013
Mericitabine is a nucleoside analog polymerase inhibitor of HCV. Treatment-naive HCV genotype 1 or 4 patients were randomized to double-blind treatment with oral mericitabine at a dosage of 500 mg BID for 12 weeks (A); 1000 mg BID for 8 weeks (B), or 12 weeks (C, D); or placebo BID ...
Teo I - - 2013
The wide-awake hand surgery (WAHS) technique involves injecting lidocaine with adrenaline for hand surgical procedures that are done without the use of tourniquets, sedation, regional or general anaesthetic. This is a retrospective review of the first 100 consecutive patients who underwent operations using this technique at our centre. The operations ...
Coulson Michelle - - 2013
BACKGROUND: This study examined the correlation between Inhibin B and testicular pathology. METHODS: Male Han Wistar rats (approximately 10 weeks old) were administered either vehicle or an endothelin receptor antagonist (ET-An) orally for 28 days or a Gonadotropin Releasing Hormone (GnRH) agonist (GnRH-A) as a subcutaneous implant on day 1. ...
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