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Tonduti Davide - - 2013
A novel leukoencephalopathy, termed hypomyelinating leukoencephalopathy affecting early myelinating structures (HEMS), was recently described. Here we report on two patients affected by HEMS with a clinical picture characterized by early-onset nystagmus and thereafter progressive cerebellar signs and mild spasticity predominantly affecting the legs. In one patient, who has the longest ...
Picas Laura - - 2013
The erythrocyte membrane, a metabolically regulated active structure that comprises lipid molecules, junctional complexes and the spectrin network, enables the cell to undergo large passive deformations when passing through the microvascular system. Here we use atomic force microscopy (AFM) imaging and quantitative mechanical mapping at nanometer resolution to correlate structure ...
Wystrach Antoine - - 2013
Ants can use visual information to guide long idiosyncratic routes and accurately pinpoint locations in complex natural environments. It has often been assumed that the world knowledge of these foragers consists of multiple discrete views that are retrieved sequentially for breaking routes into sections controlling approaches to a goal. Here ...
Tandon Teena - - 2013
BackgroundShorter delivered dialysis times are associated with increased all-cause mortality. Whether shorter delivered dialysis times also associate with an increase in blood pressure (BP) and reduce the ability of probing dry weight to lower BP is unclear.MethodsAmong patients participating in the Dry-Weight Reduction in Hypertensive Hemodialysis Patients (DRIP) trial, interdialytic ...
Roos Anne-Marie - - 2013
INTRODUCTION: Sexual function of women suffering from pelvic organ prolapse (POP) and/or urinary incontinence (UI) is adversely affected. However, our current understanding of the exact relationship between female sexual dysfunction and POP and/or UI is incomplete. A qualitative study can improve our understanding by describing what women themselves perceive as ...
de Boer Y S - - 2013
BACKGROUND: Ten percent of patients with autoimmune hepatitis (AIH) are nonresponsive or intolerant to thiopurine therapy. A skewed metabolism, leading to the preferential generation of (hepato)toxic thiopurine metabolites (6-MMPs) instead of the metabolic active 6-tioguanine (thioguanine) nucleotides (6-TGNs), may explain this unfavourable outcome. Co-administration of allopurinol to low-dose thiopurine therapy ...
Cougle Jesse R - - 2013
OBJECTIVE: Recently, researchers have called for therapeutic applications of behavioral primes (Shalev & Bargh, 2011). We evaluated whether courageous approach behavior might be facilitated through priming in a sample of spider fearful women. METHOD: Undergraduate student women reporting elevated spider fear (N = 33, Age mean = 18.88) were recruited ...
Zetlitz Elisabeth - - 2013
INTRODUCTION: Post-partum vaginal laxity is a problem encountered by many women. More uncommon is a resulting vaginal defect. In most cases of laxity, a period of extensive physiotherapy can strengthen the pelvic muscles enough for symptoms to be minimized. However, this is not the case once there is a tissue ...
Wang Zheng - - 2013
Single-crystalline niobium oxide fluoride (Nb(3)O(7)F) hierarchical nanostructures are firstly prepared via a facile hydrothermal method without using any template or surfactant. The results of scanning electron microscopy and transmission electron microscopy showed that the hierarchical morphology of Nb(3)O(7)F could be effectively controlled by adjusting the reaction time. Ultraviolet-visible spectra showed ...
Siskind Eric - - 2013
INTRODUCTION: Non-invasive imaging studies can provide visualization of allograft perfusion in the postoperative evaluation of newly transplanted renal allografts. AIM: The purpose of our study was to evaluate the significance of elevated renal artery velocities in the immediate postoperative period. METHODS: Peak systolic velocities (PSVs) were obtained in the transplanted ...
Demircan Yağmur - - 2013
DEP is a label-free, noninvasive, stand-alone, rapid, and sensitive particle manipulation and characterization technique. Improvements in Micro-Electro-Mechanical Systems (MEMS) technology have enabled the biomedical applications of DEP over the past decades. By this way, integration of DEP into Lab-on-a-Chip (LOC) systems has become achievable, creating a potential tool for point-of-care ...
Johnson Lacey - - 2013
BACKGROUND: Platelet (PLT) concentrates frozen in dimethyl sulfoxide (DMSO) can be stored for extended periods at -80°C. PLTs are frozen in a hyperconcentrated state to avoid postthaw washing and minimize residual DMSO. Consequently, PLTs require reconstitution upon thawing. Although plasma, saline, and PLT additive solutions (PASs) have been used to ...
Liu Jun - - 2013
Limited nutrient diffusion in three-dimensional (3D) constructs is a major concern in tissue engineering. Therefore, monitoring nutrient availability and diffusion within a scaffold is an important asset. Since nutrients come in various forms, we have investigated the diffusion of the oxygen, luciferin and dextran molecules within tissue-engineered constructs using optical ...
Carach Chris - - 2013
Thermally-induced chain ordering (aggregation) and oxidative damage in neat poly(3-hexylthiophene, P3HT) films was assessed using multiple optical metrics (low temperature photoluminescence (LT-PL), Raman, absorbance, and IR spectroscopies) and NMR through quantitative analysis of exciton/chromophore bandwidths, emission, vibronic lineshapes, and changes in film chemistry. Polymer morphology is discussed in light of ...
Voigt Christian C - - 2013
Infection of North American bats with the keratin-digesting fungus Geomyces destructans often result in holes and ruptures of wing membranes, yet it is unknown if flight performance and metabolism of bats are altered by such injuries. I conducted flight experiments in a circular flight arena in Myotis albescens and M. ...
Vogel Isabel - - 2013
Costimulatory signals are required for priming and activation of naive T cells, while it is less clear how they contribute to induction of regulatory T-cell activity. We previously reported that the blockade of the B7-CD28 and CD40L-CD40 interaction efficiently suppresses allogeneic T-cell activation in vivo. This was characterized by an ...
Edelman Natalie Lois - - 2013
OBJECTIVES: Evidence suggests substance-misusing women (SMW) experience disproportionate sexual health morbidity and poor uptake of interventions including contraception and cervical screening, yet there has been little investigation of sexual health service access issues for this population. METHODS: Twenty women with problem drug use in Hastings in South East England, UK ...
de Leeuw Jacqueline - - 2013
ObjectiveTo investigate the health-related quality of life (HRQoL) and supportive follow-up care needs 1 month posttreatment for patients with advanced-stage (stage III or IV) radiated head and neck cancer (HNC) who were treated with curative intent.Study DesignAn exploratory, descriptive analysis of HRQoL data obtained from 3 treatment groups: conventional radiotherapy ...
Chin Nicholas - - 2013
BACKGROUND: Accurate and comprehensive clinical documentation is crucial for effective ongoing patient care, follow-up and to optimize case mix based funding. Each Diagnostic Related Group (DRG) is assigned a "weight": leading to Weighted Inlier Equivalent Separation (WIES), a system many public and private hospitals in Australia subscribe to. AIMS: To ...
Sano Naoki - - 2013
A highly cross-linked polyviologen hydrogel, poly(tripyridiniomesitylene) (PTPM), was designed as an anode-active material. It displayed a reversible two-electron redox capability at -0.4 and -0.8 V vs. Ag/AgCl in an aqueous electrolyte. The PTPM layer coated on a current collector by electropolymerization via 4-cyanopyridinium electro-coupling reaction demonstrated a rapid charging-discharging reaction ...
Tan Wah Ching - - 2013
OBJECTIVES: To determine the effect of various systemic antibiotic prophylaxis regimes on patient-reported outcomes and postsurgical complications in patients undergoing conventional implant installation. MATERIAL AND METHODS: Three hundred and twenty-nine healthy adults in need of conventional implant installation were randomly assigned to one of four groups: (i) preoperatively 2 g of ...
Gallo Amy - - 2013
It is encouraging that we are improving the technical aspects of treatment modalities for biliary atresia. However, it is clear that more needs to be done to best develop new treatment plans while applying the modalities we have (porto-enterostomy or liver transplantation or both) in a way that will afford ...
Xu Wenwu - - 2013
A time-dependent quantum wave packet method is used to investigate the dynamics of the He + HeH+( ) reaction based on a new potential energy surface [Liang et al., J. Chem. Phys., 136, 094307 (2012)]. The Coupled channel (CC) and centrifugal-sudden (CS) reaction probabilities as well as the total integral ...
López-Candales Angel - - 2013
BACKGROUND: Even though chronic pulmonary hypertension (cPH) and acute pulmonary embolism (aPE) increase pulmonary vascular resistance and result in right ventricular (RV) dilatation and systolic dysfunction; both conditions operate through drastically different mechanisms. Unfortunately, simple echocardiographic examination might be insufficient to distinguish both entities. This study attempted to determine which ...
Benato L - - 2013
A seven-year-old, ovariohysterectomised female dwarf lop rabbit (Oryctolagus cuniculus) was referred with severe swelling and erythema of the mucocutaneous junctions of the lips, nares and vulva. Bilateral, severe periocular dermatitis was also present. Heavy pure growths of a member of the Staphylococcus intermedius group were cultured from nasal and aural ...
Margraf Johannes T - - 2013
We have investigated the role of linker molecules in quantum-dot-sensitized solar cells (QDSSCs) using density-functional theory (DFT) and experiment. Linkers govern the number of attached QDs, but also influence charge separation, recombination, and transport. Understanding their behavior is therefore not straightforward. DFT calculations show that mercaptopropionic acid (MPA) and cysteine ...
Saito Mayumi - - 2013
While walking is considered a task demanding cognitive functions rather than an automatic motor task, it is still unclear whether cognitive tasks influence interlimb coordination during walking. The present study revealed that the elderly require cognitive function to control temporal interlimb coordination under difficult walking conditions. Risk of falls is ...
Maniglio Roberto - - 2013
Maniglio R. The impact of child sexual abuse on the course of bipolar disorder: a systematic review. Bipolar Disord 2013: 00: 000-000. © 2013 John Wiley & Sons A/S.Published by Blackwell Publishing Ltd. Objectives:  The aim of this review was to elucidate the impact of child sexual abuse on all ...
Armando M R - - 2013
AIM: to evaluate the ability of probiotic Saccharomyces cerevisiae RC016 strain to reduce fumonisin B(1) (FB(1) ) in vitro and to optimize the culture conditions for the growth of the yeast employing surface response methodology. METHODS AND RESULTS: Using Plackett-Burman screening designs (PBSD) and central composite designs (CCD), an optimized ...
Durantini Andres Matias - - 2013
The behavior of 4-aminophthalimide (4-AP), a common molecular probe utilized in solvation dynamics experiments, was revisited in polar aprotic and protic solvents using absorption, steady-state and time-resolved fluorescence (TRES) techniques. Also, the deuterium isotope effect was investigated using D2O as solvent. The absorption spectra of 4-AP consist of two absorption ...
Simpson Cherie - - 2013
Purpose: The purpose was to obtain a better understanding of the role of mastery (global and caregiving) in wives' versus daughters' experience of caring for a person with dementia. Method: A total of 67 caregivers participated in a cross-sectional study. Variables measured were global mastery, caregiving mastery, stress, and depressive ...
Landi Elena - - 2013
Porous macro-granules of nanostructured apatite with Ca ions partially cosubstituted with Mg and Sr ions in different ratios (SrMgHAs), were synthesized at 37°C and compared with Mg and/or Sr free apatites (MgHAs and HA). Strontium improved the Mg substitution extent in the apatite and the chemical-physical and thermal stability of ...
Voltas Jordi - - 2013
Winter-drought induced forest diebacks in the low-latitude margins of species' distribution ranges can provide new insights into the mechanisms (carbon starvation, hydraulic failure) underlying contrasting tree reactions. We analysed a winter-drought induced dieback at the Scots pine's southern edge through a dual-isotope approach (Δ(13) C and δ(18) O in tree-ring ...
Rahardjo Harrina E - - 2013
INTRODUCTION.: Vasoactive peptides, such as bradykinin, C-type natriuretic peptide (CNP), vasoactive intestinal polypeptide (VIP), and endothelin 1 (ET-1), are assumed to be involved in the control of female genital vascular and nonvascular smooth muscle. Tissue levels of said peptides are controlled by the activity of endopeptidase enzymes. Theoretically, in female ...
Tian Ji-Xin - - 2013
In this report, the in vitro metabolism of Strychnos alkaloids was investigated using liquid chromatography/high-resolution mass spectrometry for the first time. Strychnine and brucine were selected as model compounds to determine the universal biotransformations of the Strychnos alkaloids in rat liver microsomes. The incubation mixtures were separated by a bidentate-C(18) ...
Mayoral Maria Jose - - 2013
A new oligophenyleneethynylene (OPE)-based Pd(II) pyridyl complex has been synthesized and its self-assembly in solution, in the bulk state and on surfaces investigated. Detailed analysis of concentration- and temperature-dependent UV-Vis studies in methylcyclohexane supported by DFT calculations demonstrate for the first time that cooperative supramolecular polymerization processes can be driven ...
Risco D - - 2013
Porcine brucellosis is a disease caused by Brucella suis, which is characterized by reproductive disorders in pigs. The number of cases of swine brucellosis has risen in many European countries, likely because of the presence of a wild reservoir of B. suis in wild boar. This study aimed at evaluating factors ...
Franks Z - - 2013
Methicillin-resistant Staphylococcus aureus (MRSA ) induces a pro-thrombotic and pro-inflammatory milieu. Although timely antibiotic administration in MRSA sepsis may improve outcomes by arresting bacterial growth, the effects of antibiotics on mitigating injurious thrombo-inflammatory cellular responses remains unexplored. Using a newly developed human whole blood model and an in vivo mouse ...
Gómez-Ortíz Nikte Maricela - - 2013
The presence and deteriorating action of microbial biofilms on historic stone buildings have received considerable attention in the last few years. Among microorganisms, fungi are one of the most damaging groups. In the present work, antimicrobial surfaces were prepared using suspensions of Ca(OH)(2) particles, mixed with ZnO or TiO(2) nanoparticles. ...
Kokosar Janez - - 2013
Molecular domestications of transposable elements have occurred repeatedly during the evolution of eukaryotes. Vertebrates, especially mammals, possess numerous single copy domesticated genes (DGs) that have originated from the intronless multicopy transposable elements. However, the origin and evolution of the retroelement-derived DGs (RDDGs) that originated from Metaviridae has been only partially ...
Haydin Sertac - - 2013
Congenital complete atrioventricular block can be concomitant with congenital heart diseases or maternal connective tissue disorders like systemic lupus erythematosus and Sjögren's syndrome. Such patients may require implantation of a permanent pacemaker due to ventricular dysfunction. While many methods of pacemaker implantation have been tested, one that is optimal for ...
Brown Jason C L - - 2013
Hibernating ground squirrels (Ictidomys tridecemlineatus) alternate between two distinct metabolic states throughout winter: torpor, during which metabolic rate (MR) and body temperature (T(b)) are considerably suppressed, and interbout euthermia (IBE), during which MR and T(b) briefly return to euthermic levels. Previous studies showed suppression of succinate-fueled respiration during torpor in ...
Tedore Cynthia - - 2013
In diverse and productive habitats, predaceous arthropods are expected to frequently encounter dangerous conspecifics and heterospecifics. This should make quick and accurate discriminations between species and sexes adaptive. By simultaneously sampling both visual cues and pheromones, and by utilizing stringent species- and sex-specific visual recognition templates, an individual should be ...
Griffin John F JF - - 2013
PURPOSE: To analyze four clinically applicable diffusion tensor imaging (DTI) protocols (two each in the transverse and sagittal planes) in the normal dog. MATERIALS AND METHODS: Seven healthy Dachshund dogs were scanned with four DTI protocols. Within each plane, identical spatial resolution was used while the number of diffusion-encoding directions ...
Hirschfield Gideon M - - 2013
Primary biliary cirrhosis (PBC) is an autoimmune disease characterized by clinical homogeneity among patients, an overwhelming female predominance, production of a multilineage immune response to mitochondrial autoantigens, inflammation of small bile ducts, and in some patients the development of fibrosis and cirrhosis. The targets in this disease are small bile ...
Braham Amel - - 2013
AIM: The study aimed to examine whether the Arabic version of the Comprehensive Assessment of At Risk Mental States (CAARMS) has good construct validity, concurrent validity and reliability. METHODS: Validity was established on a sample of 58 Tunisian adolescents and young adults aged between 16 and 30 years. These subjects ...
Giannakopoulou Trisevgeni - - 2013
PURPOSE: It is widely accepted that monocular deprivation results in improved visual performance in the non-pathological eye. The current study investigates the effect of deprivation due to severe impairment in one eye during late childhood or adulthood, on the spatial performance of the fellow 'good' eye. METHODS: Twenty patients (age: ...
Tsuchiya Kyoichiro - - 2013
Insulin signaling in vascular endothelial cells is critical to maintain endothelial function but also to mediate insulin action on peripheral glucose disposal. However, gene knockout studies have reached disparate conclusions. Thus, insulin receptor inactivation in endothelial cells does not impair insulin action, whereas inactivation of Irs2 does. Previously, we have ...
Raczynska Ewa Daniela - - 2013
All possible twenty-three prototropic tautomers of neutral and redox adenine (nine amine and fourteen imine forms, including geometric isomerism of the exo =NH group) were examined in vacuo {DFT(B3LYP)/6-311+G(d,p)}. The NH ---> NH conversions as well as those usually omitted, NH ---> CH and CH ---> CH, were considered. An ...
Cubrilovic Dragana - - 2013
Due to its favorable physicochemical properties, DMSO is the standard solvent for sample storage and handling of compounds in drug discovery. To date, little attention was given to how DMSO influences protein-ligand binding strengths. In this study we investigated the effects of DMSO on different noncovalent protein-ligand complexes, in particular ...
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