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Results 601 - 650 of 2825
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Groeneveldt Lara - - 2013
ABSTRACT: BACKGROUND: Exercise programmes are beneficial for cancer patients however evidence is limited in patients with multiple myeloma (MM), a cancer that is characterised by osteolytic bone disease, giving rise to high levels of bone morbidity including fractures and bone pain. METHODS: We conducted a single arm phase 2 study ...
Clark-Price Stuart C - - 2013
OBJECTIVE: To compare a towel under, a warm water pad under or a forced warm air blanket over dogs as techniques to reduce heat loss during a standardized anesthetic. STUDY DESIGN: Prospective, randomized, crossover study. ANIMALS: Eight, healthy, mixed breed dogs weighing 16.3-19.6 kg. METHODS: Dogs were anesthetized four times for ...
Bago-Rozankovic Petra - - 2013
The papillary carcinoma of the thyroid gland is the most common type of tumor of the thyroid gland with good prognosis and low incidence of distant metastasis. The brain metastases of thyroid gland carcinoma are extremely rare. We report a patient with multiple cystic brain lesions and satisfying criteria for ...
Lima Steven L - - 2013
Many aspects of animal behaviour are affected by real-time changes in the risk of predation. This conclusion holds for virtually all taxa and ecological systems studied, but does it hold for bats? Bats are poorly represented in the literature on anti-predator behaviour, which may reflect a lack of nocturnal predators ...
Courand Pierre-Yves - - 2013
BACKGROUND: Late presentation of abnormal origin of coronary artery from the pulmonary artery (ACAPA) is uncommon compared with early presentation, which usually induces extended myocardial necrosis and severe heart failure. The late presentation is characterized by abundant development of intercoronary collaterals resulting in mild and rare symptoms, but nevertheless can ...
Seike Kensaku - - 2013
OBJECTIVES: Trichomonas vaginalis is one of the pathogens causing sexually transmitted infections. This microorganism is a common pathogen among women, but its significance as a cause of morbidity among men remains uncertain. We sought to determine the prevalence and morbidity of T. vaginalis infection in Japanese men with and without ...
Monajjemi Majid - - 2013
In BnNn cages or tubes, when the quasi borazine rings are attached to each other through a pair of common atoms of B and N, the bonding structure is named class A, On the other hand, there are some BnNn rings including a covalent bond between two atoms of B ...
Gu Junsi - - 2013
An electrochemical liquid-liquid-solid (ec-LLS) process that yields crystalline silicon at low temperature (80 °C) without any physical or chemical templating agent has been demonstrated. Electroreduction of dissolved SiCl(4) in propylene carbonate using a liquid gallium [Ga(l)] pool as the working electrode consistently yielded crystalline Si. X-ray diffraction and electron diffraction ...
Baglin T - - 2013
Oral direct inhibitors (ODIs) of thrombin and factor Xa are now approved as anticoagulant drugs. The first two drugs to complete phase III clinical trials for thromboprophylaxis in orthopaedic surgery and treatment of patients with atrial fibrillation or venous thromboembolism were dabigatran and rivaroxaban. These small molecules are given at ...
Riyaz-Ul-Hassan Syed - - 2013
In this study, methodologies were developed for cost-effective, rapid and user-friendly culture-independent detection of Salmonella in milk by real-time PCR. The SYBR Green based real-time PCR assay was standardized with primers targeting the Salmonella enterotoxin gene (stn) that have been earlier used for its detection by conventional PCR. Inclusivity tests ...
Giuliano François - - 2013
INTRODUCTION: Tadalafil, a long-acting phosphodiesterase type 5 inhibitor, is approved for treating signs and symptoms of benign prostatic hyperplasia (BPH) and erectile dysfunction (ED); tamsulosin, an alpha-blocker, is approved for treating signs and symptoms of BPH. AIM: To determine the effects of tadalafil or tamsulosin on sexual function, including ejaculation ...
Schüttler Christian - - 2013
Both, cis- and trans-3,4-disubstituted thiadiazolidines 5 and 6 can enantioselectively be obtained from thiadiazoles 2 which, in turn, are efficiently prepared from the respective 1,2-diketone by an improved protocol. An asymmetric ruthenium-catalyzed transfer hydrogenation followed by a diastereoselective hydride addition furnishes exclusively the cis-isomers 5 which, under acidic conditions, undergo ...
Huang Franklin W - - 2013
Systematic sequencing of human cancer genomes has identified many recurrent mutations in the protein coding regions of genes but rarely in gene regulatory regions. Here, we describe two independent mutations within the core promoter of TERT, the gene coding for the catalytic subunit of telomerase, which collectively occur in 50 ...
Horn Susanne - - 2013
Cutaneous melanoma occurs in both familial and sporadic forms. We investigated a melanoma-prone family through linkage analysis and high-throughput sequencing and identified a disease-segregating germ line mutation in the promoter of the telomerase reverse transcriptase (TERT) gene, which encodes the catalytic subunit of telomerase. The mutation creates a new binding ...
Li Xiangming - - 2013
The ability to generate a large area micropillar array with spatially varying heights allows for exploring numerous new interesting applications in biotechnology, surface engineering, microfluidics, etc. This letter presents a clever and straightforward method, called electrically modulated microtransfer molding (EM3), for generating such unique micro-structures from a silicon mold arrayed ...
Enright Brian P - - 2013
BACKGROUND: This study was conducted as part of an ILSI-HESIconsortium effort to assess the utility of circulating inhibin B as an early biomarker of testicular toxicity in rats. METHODS: Two known testicular toxicants were selected for use in this study: ethylene glycol monomethyl ether (EGME) and dibromoacetic acid (DBAA). EGME ...
Geist Matthias F - - 2013
Nanocomposites made from Na-Montmorillonite and metallo-supramolecular polyelectrolytes (MEPE) based on nickel and ditopic bis-terpyridine ligands are prepared by an aqueous synthesis. Intercalation is confirmed by IR-spectroscopy, thermogravimetric analysis and X-ray powder diffraction. The rheological response in the presence of an electric field of the dispersed nanocomposites in silicon oil is ...
Jacono Andrew A - - 2013
OBJECTIVE To aid the aesthetic surgeon in midface analysis and selection of treatment plans offering the greatest likelihood of success in midface rejuvenation. METHODS We performed a retrospective review of all patients who underwent surgical midface rejuvenation by a single surgeon. We recorded demographics, history, procedures, outcomes, and complications. Results ...
Lendrum Robbie A - - 2013
A case of pre-hospital administration of prothrombin complex concentrate to a patient anticoagulated with warfarin and with suspected intracranial haemorrhage is described. Effective, early reversal of anticoagulation by the time of arrival at hospital was achieved.
Mollet Karen - - 2013
The reactivity of 3-hydroxy-4-(1,2-dihydroxyethyl)-β-lactams with regard to the oxidant sodium periodate was evaluated, unexpectedly resulting in the exclusive formation of new 2-hydroxy-1,4-oxazin-3-ones through a C3C4 bond cleavage of the intermediate 4-formyl-3-hydroxy-β-lactams followed by a ring expansion. This peculiar transformation stands in sharp contrast with the known NaIO(4) -mediated oxidation of ...
Tomita Katsuyuki - - 2013
BACKGROUND: To predict the presence of asthma in adult patients with respiratory symptoms, we developed a scoring algorithm using clinical parameters. METHODS: We prospectively analysed 566 adult outpatients who visited Kinki University Hospital for the first time with complaints of nonspecific respiratory symptoms. Asthma was comprehensively diagnosed by specialists using ...
Case Amy A - - 2013
Abstract In this review we discuss the history of Hospice and Palliative Medicine (HPM) physician education in the United States over the last 20 years, as there has been dramatic growth in our specialty during this time. A Medline literature search was completed and we surveyed leaders in the field ...
Semark Birgitta - - 2013
PURPOSE: Socioeconomic factors have been suggested to influence the prescribing of newer and more expensive drugs. In the present study, individual and health care provider factors were studied in relation to the prevalence of differently priced drugs. METHODS: Register data for dispensed drugs were retrieved for 18 486 individuals in a ...
van Es J - - 2013
INTRODUCTION: Little is known about the natural history of clot resolution in the initial weeks of anticoagulant therapy in patients with acute pulmonary embolism (PE). Clot resolution of acute pulmonary embolism (PE) was assessed with either computed tomography pulmonary angiography (CT-scan) or perfusion scintigraphy (Q-scan) after 3 weeks of treatment. ...
Kim Gun-Hwa - - 2013
Type 2 diabetes mellitus (T2DM) is the most prevalent and serious metabolic disease affecting people worldwide. T2DM results from insulin resistance of the liver, muscle, and adipose tissue. In this study we used proteomic and bioinformatic methodologies to identify novel hepatic membrane proteins that are related to the development of ...
Tonduti Davide - - 2013
A novel leukoencephalopathy, termed hypomyelinating leukoencephalopathy affecting early myelinating structures (HEMS), was recently described. Here we report on two patients affected by HEMS with a clinical picture characterized by early-onset nystagmus and thereafter progressive cerebellar signs and mild spasticity predominantly affecting the legs. In one patient, who has the longest ...
Picas Laura - - 2013
The erythrocyte membrane, a metabolically regulated active structure that comprises lipid molecules, junctional complexes and the spectrin network, enables the cell to undergo large passive deformations when passing through the microvascular system. Here we use atomic force microscopy (AFM) imaging and quantitative mechanical mapping at nanometer resolution to correlate structure ...
Wystrach Antoine - - 2013
Ants can use visual information to guide long idiosyncratic routes and accurately pinpoint locations in complex natural environments. It has often been assumed that the world knowledge of these foragers consists of multiple discrete views that are retrieved sequentially for breaking routes into sections controlling approaches to a goal. Here ...
Roos Anne-Marie - - 2013
INTRODUCTION: Sexual function of women suffering from pelvic organ prolapse (POP) and/or urinary incontinence (UI) is adversely affected. However, our current understanding of the exact relationship between female sexual dysfunction and POP and/or UI is incomplete. A qualitative study can improve our understanding by describing what women themselves perceive as ...
de Boer Y S - - 2013
BACKGROUND: Ten percent of patients with autoimmune hepatitis (AIH) are nonresponsive or intolerant to thiopurine therapy. A skewed metabolism, leading to the preferential generation of (hepato)toxic thiopurine metabolites (6-MMPs) instead of the metabolic active 6-tioguanine (thioguanine) nucleotides (6-TGNs), may explain this unfavourable outcome. Co-administration of allopurinol to low-dose thiopurine therapy ...
Cougle Jesse R - - 2013
OBJECTIVE: Recently, researchers have called for therapeutic applications of behavioral primes (Shalev & Bargh, 2011). We evaluated whether courageous approach behavior might be facilitated through priming in a sample of spider fearful women. METHOD: Undergraduate student women reporting elevated spider fear (N = 33, Age mean = 18.88) were recruited ...
Wang Zheng - - 2013
Single-crystalline niobium oxide fluoride (Nb(3)O(7)F) hierarchical nanostructures are firstly prepared via a facile hydrothermal method without using any template or surfactant. The results of scanning electron microscopy and transmission electron microscopy showed that the hierarchical morphology of Nb(3)O(7)F could be effectively controlled by adjusting the reaction time. Ultraviolet-visible spectra showed ...
Siskind Eric - - 2013
INTRODUCTION: Non-invasive imaging studies can provide visualization of allograft perfusion in the postoperative evaluation of newly transplanted renal allografts. AIM: The purpose of our study was to evaluate the significance of elevated renal artery velocities in the immediate postoperative period. METHODS: Peak systolic velocities (PSVs) were obtained in the transplanted ...
Demircan Yağmur - - 2013
DEP is a label-free, noninvasive, stand-alone, rapid, and sensitive particle manipulation and characterization technique. Improvements in Micro-Electro-Mechanical Systems (MEMS) technology have enabled the biomedical applications of DEP over the past decades. By this way, integration of DEP into Lab-on-a-Chip (LOC) systems has become achievable, creating a potential tool for point-of-care ...
Johnson Lacey - - 2013
BACKGROUND: Platelet (PLT) concentrates frozen in dimethyl sulfoxide (DMSO) can be stored for extended periods at -80°C. PLTs are frozen in a hyperconcentrated state to avoid postthaw washing and minimize residual DMSO. Consequently, PLTs require reconstitution upon thawing. Although plasma, saline, and PLT additive solutions (PASs) have been used to ...
Liu Jun - - 2013
Limited nutrient diffusion in three-dimensional (3D) constructs is a major concern in tissue engineering. Therefore, monitoring nutrient availability and diffusion within a scaffold is an important asset. Since nutrients come in various forms, we have investigated the diffusion of the oxygen, luciferin and dextran molecules within tissue-engineered constructs using optical ...
Carach Chris - - 2013
Thermally-induced chain ordering (aggregation) and oxidative damage in neat poly(3-hexylthiophene, P3HT) films was assessed using multiple optical metrics (low temperature photoluminescence (LT-PL), Raman, absorbance, and IR spectroscopies) and NMR through quantitative analysis of exciton/chromophore bandwidths, emission, vibronic lineshapes, and changes in film chemistry. Polymer morphology is discussed in light of ...
Voigt Christian C - - 2013
Infection of North American bats with the keratin-digesting fungus Geomyces destructans often result in holes and ruptures of wing membranes, yet it is unknown if flight performance and metabolism of bats are altered by such injuries. I conducted flight experiments in a circular flight arena in Myotis albescens and M. ...
Vogel Isabel - - 2013
Costimulatory signals are required for priming and activation of naive T cells, while it is less clear how they contribute to induction of regulatory T-cell activity. We previously reported that the blockade of the B7-CD28 and CD40L-CD40 interaction efficiently suppresses allogeneic T-cell activation in vivo. This was characterized by an ...
Edelman Natalie Lois - - 2013
OBJECTIVES: Evidence suggests substance-misusing women (SMW) experience disproportionate sexual health morbidity and poor uptake of interventions including contraception and cervical screening, yet there has been little investigation of sexual health service access issues for this population. METHODS: Twenty women with problem drug use in Hastings in South East England, UK ...
de Leeuw Jacqueline - - 2013
ObjectiveTo investigate the health-related quality of life (HRQoL) and supportive follow-up care needs 1 month posttreatment for patients with advanced-stage (stage III or IV) radiated head and neck cancer (HNC) who were treated with curative intent.Study DesignAn exploratory, descriptive analysis of HRQoL data obtained from 3 treatment groups: conventional radiotherapy ...
Chin Nicholas - - 2013
BACKGROUND: Accurate and comprehensive clinical documentation is crucial for effective ongoing patient care, follow-up and to optimize case mix based funding. Each Diagnostic Related Group (DRG) is assigned a "weight": leading to Weighted Inlier Equivalent Separation (WIES), a system many public and private hospitals in Australia subscribe to. AIMS: To ...
Sano Naoki - - 2013
A highly cross-linked polyviologen hydrogel, poly(tripyridiniomesitylene) (PTPM), was designed as an anode-active material. It displayed a reversible two-electron redox capability at -0.4 and -0.8 V vs. Ag/AgCl in an aqueous electrolyte. The PTPM layer coated on a current collector by electropolymerization via 4-cyanopyridinium electro-coupling reaction demonstrated a rapid charging-discharging reaction ...
Tan Wah Ching - - 2013
OBJECTIVES: To determine the effect of various systemic antibiotic prophylaxis regimes on patient-reported outcomes and postsurgical complications in patients undergoing conventional implant installation. MATERIAL AND METHODS: Three hundred and twenty-nine healthy adults in need of conventional implant installation were randomly assigned to one of four groups: (i) preoperatively 2 g of ...
Gallo Amy - - 2013
It is encouraging that we are improving the technical aspects of treatment modalities for biliary atresia. However, it is clear that more needs to be done to best develop new treatment plans while applying the modalities we have (porto-enterostomy or liver transplantation or both) in a way that will afford ...
Xu Wenwu - - 2013
A time-dependent quantum wave packet method is used to investigate the dynamics of the He + HeH+( ) reaction based on a new potential energy surface [Liang et al., J. Chem. Phys., 136, 094307 (2012)]. The Coupled channel (CC) and centrifugal-sudden (CS) reaction probabilities as well as the total integral ...
López-Candales Angel - - 2013
BACKGROUND: Even though chronic pulmonary hypertension (cPH) and acute pulmonary embolism (aPE) increase pulmonary vascular resistance and result in right ventricular (RV) dilatation and systolic dysfunction; both conditions operate through drastically different mechanisms. Unfortunately, simple echocardiographic examination might be insufficient to distinguish both entities. This study attempted to determine which ...
Benato L - - 2013
A seven-year-old, ovariohysterectomised female dwarf lop rabbit (Oryctolagus cuniculus) was referred with severe swelling and erythema of the mucocutaneous junctions of the lips, nares and vulva. Bilateral, severe periocular dermatitis was also present. Heavy pure growths of a member of the Staphylococcus intermedius group were cultured from nasal and aural ...
Margraf Johannes T - - 2013
We have investigated the role of linker molecules in quantum-dot-sensitized solar cells (QDSSCs) using density-functional theory (DFT) and experiment. Linkers govern the number of attached QDs, but also influence charge separation, recombination, and transport. Understanding their behavior is therefore not straightforward. DFT calculations show that mercaptopropionic acid (MPA) and cysteine ...
Saito Mayumi - - 2013
While walking is considered a task demanding cognitive functions rather than an automatic motor task, it is still unclear whether cognitive tasks influence interlimb coordination during walking. The present study revealed that the elderly require cognitive function to control temporal interlimb coordination under difficult walking conditions. Risk of falls is ...
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