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Obdeijn Inge-Marie - - 2013
In breast cancer patients eligible for breast-conserving surgery, we evaluated whether the information provided by preoperative MRI of the breast would result in fewer tumor-positive resection margins and fewer reoperations. The study group consisted of 123 consecutive patients diagnosed with either breast cancer or ductal carcinoma in situ eligible for ...
Pinto Reis Catarina - - 2013
Effective formulation for peptide and protein delivery through the oral route has always been the critical effort with the advent of biotechnology. Stability, enzymatic degradation and ineffective absorption are common difficulties found for conventional dosage forms. As a result, new drug-delivery approaches are used to circumvent these limitations and enhance ...
Chakraverty Julian K - - 2013
The purpose of this study was to use CT to determine the presence of radiologic parameters associated with cam and pincer femoroacetabular impingement (FAI) in a young population without symptoms. A retrospective review of 50 patients (age range, 20-40 years) with no current or previous hip disorder who underwent CT ...
Hossain Delwar - - 2013
We aimed to ascertain the extent of mental health problems in rural communities of southwest Queensland. Twelve workshops were conducted within this region, asking community members about the issues which were affecting their mental health, the gaps in services and facilities, and suggestions as to how to strengthen their capacity ...
Veith Frank J - - 2013
The results of good randomized controlled trials (RCTs) published in leading peer-reviewed journals have been deemed the best possible basis for good medical practice. However, several limitations may decrease their value. These include flaws and weaknesses in the design and the timeliness of RCTs. Progress in a treatment method or ...
Costantini Danny L - - 2013
The utility of dual-time-point (18)F-FDG PET/CT in differentiating benign from malignant processes in pediatric patients was assessed. Twenty-one patients (13 girls and eight boys; age range, 1-17 years) with suspected malignancy underwent dual-time-point FDG PET/CT. Scan 1 was performed at approximately 60 minutes after IV injection of 5.18 MBq/kg of ...
Thitinunsomboon Somboon - - 2013
Gamma-aminobutyric acid (GABA), commonly produced by germination of brown rice grain, is a free amino acid which could help relieving or preventing non-communicable diseases in human. Several research works have been conducted on GABA production from germinated brown rice. However, the yielded GABA (10.1-69.2 mg/100 g germinated brown rice) was comparatively low; ...
Landis Margaret S - - 2013
Many prodrug reviews describe specific examples of the successful application of prodrug technology to produce blockbuster drugs, such as simvastatin, omeprazole, acyclovir and enalapril. These reviews are helpful to understand the previous success stories and case histories of prodrug technology. The aim of the current review seeks to more clearly ...
Ruchman Richard B - - 2013
Informal conversations and anecdotal evidence suggest that the job turnover rate among radiology residency program directors is disproportionately high. The purpose of our study was to assess the characteristics of current program directors and determine factors that may be affecting overall job satisfaction and job turnover rate. A survey that ...
Knutson Lori - - 2013
Public demand for complementary and alternative medicine (CAM) therapies, often referred to as integrative health (IH), continues to grow. Health systems are now pursing the integration of these therapies with conventional medical care. This article describes the development and evolution of 1 nursing-led model for the integration of CAM services ...
Flors Lucía - - 2013
The objective of our study was to evaluate the diagnostic performance of dual-source dual-energy CT (DECT) in the detection of endoleaks after thoracic endovascular aortic repair for thoracic aortic aneurysm and to investigate if a double-phase (arterial and dual-energy late delayed phase) or a single-phase (dual-energy late delayed phase) acquisition ...
Sen Indrani - - 2013
Carotid body tumors are considered rare. However, there has been an increase in the number of these tumors managed at our center in recent years. Delayed presentation with large tumors is common. We studied the clinical profile, interventions, and outcomes of these tumors and assessed the factors influencing operative neurological ...
Nougaret Stephanie - - 2013
Developments in MRI techniques have increased the role of MRI in assessment of the pelvis in women. The aims of this review are a short overview of pelvic MRI with an emphasis on diffusion-weighted MRI (DWI) and presentation of a practical approach that includes the pearls and pitfalls of DWI. ...
Vashi Reena - - 2013
The purpose of this article is to review key clinical, histologic, and imaging features of pregnancy-associated breast cancer. A discussion of imaging modalities, including mammography, ultrasound, and MRI, and imaging-based interventions available for evaluating this population is provided. Successful detection of pregnancy-associated breast cancer requires knowledge of key clinical and ...
Sahani Dushyant V - - 2013
The purpose of this review is to outline the management guidelines for the care of patients with cystic pancreatic lesions. The guidelines are as follows: Annual imaging surveillance is generally sufficient for benign serous cystadenomas smaller than 4 cm and for asymptomatic lesions. Asymptomatic thin-walled unilocular cystic lesions smaller than ...
Behr Gerald G - - 2013
The purpose of this study was to review the medical literature and the current classification of vascular anomalies to clarify common misconceptions and provide guidance for imaging and treatment. In this first article of a two-part series, we focus on the fast-flow vascular anomalies. Nonuniformity of terminology across the medical ...
Behr Gerald G - - 2013
The purpose of this article is to review the medical literature and the current classification of the vascular anomalies to clarify common misconceptions and provide guidance for imaging and treatment. In this second article of a two-part series, we focus on slow-flow vascular anomalies. Nonuniformity of terminology across the medical ...
Bonelli-Sica Juan Manuel - - 2013
The purpose of this study is to describe the MDCT findings of anomalous pulmonary venous drainage (APVD) in a pediatric population using a 256-MDCT dual-source scanner with a high-pitch protocol. MDCT is a fast and noninvasive technique that allows detailed and comprehensive visualization of APVD characteristics in a pediatric population. ...
Leung Katherine - - 2013
Pheochromocytomas are relatively rare neuroendocrine tumors of the adrenal medulla. Their variable clinical presentation and biologic behavior often make accurate diagnosis challenging. A variable spectrum of imaging appearances--some of which may also mimic other diseases--has been recognized. This article reviews the epidemiology; associations; and clinical, biochemical, pathologic, and multimodality imaging ...
Plunk Matthew - - 2013
The purpose of this article is to review common and uncommon complications of postpartum and posttermination patients and their imaging findings. A variety of imaging modalities, including ultrasound, CT, MRI, and angiography, will be presented. Knowledge of the spectrum of normal and abnormal imaging findings as well as recognition of ...
Kaneda Heather J - - 2013
Pediatric breast masses are relatively rare and most are benign. Most are either secondary to normal developmental changes or neoplastic processes with a relatively benign behavior. To fully understand pediatric breast disease, it is important to have a firm comprehension of normal development and of the various tumors that can ...
Rosenkrantz Andrew B - - 2013
Numerous prior studies have shown the utility of apparent diffusion coefficient values in cervical cancer assessment, particularly in differentiation from benign cervix. This article will discuss histogram-based analysis for detection of adverse histologic features of cervical cancer. The study by Downey et al. in this issue investigates histogram-based analysis for ...
Vashi Reena - - 2013
The purpose of this article is to review key clinical, histologic, and imaging features of expected physiologic changes within the breast and common benign breast disease in the pregnant and lactating patient. A thorough understanding of expected physiologic changes and common benign breast abnormalities of pregnancy and lactation is required ...
Yablon Corrie M - - 2013
Many musculoskeletal fellowships are nonaccredited, leading to heterogeneity of educational experiences. There is no governing body for these nonaccredited fellowships, leaving program content and rules to the program directors' discretion. In addition, imaging fellowships in general currently face many external pressures that challenge their capacity to provide a high-quality education. ...
Harris Robert D - - 2013
The Africa Mercy, a rehabilitated Danish ferry, is the largest private hospital ship in the world, devoted to providing medical and surgical care to the residents of West Africa, one of the poorest regions on the globe. There is a small radiology department on board, along with six operating rooms ...
Park Young Mi - - 2013
This article reviews the imaging and histopathologic findings of various axillary diseases and suggests management guidelines for radiologists based on imaging findings with clinical correlation. Although axillary diseases may reveal nonspecific imaging findings, a knowledge of the characteristic radiologic manifestations of specific diseases according to anatomic origin (nodal, accessory breast, ...
Chakarun Corey J - - 2013
Our purpose is to present normal and abnormal imaging findings associated with endoprosthetic reconstruction after limb-salvage surgery. Endoprosthetic reconstruction varies with the location and size of the tumor, implant designs, and complications. Radiologists need to be aware of associated imaging findings seen in postoperative infection, tumor recurrence, and hardware failure. ...
Grindlay Kate - - 2013
To estimate unintended pregnancy rates among a representative sample of 7,225 active-duty women in the U.S. military in 2008 and to compare these rates with 2005 and with the U.S. population. Cross-sectional data came from the 2008 Department of Defense Survey of Health Related Behaviors among Active Duty Military Personnel ...
Olival Kevin J - - 2013
To determine geographic range for Ebola virus, we tested 276 bats in Bangladesh. Five (3.5%) bats were positive for antibodies against Ebola Zaire and Reston viruses; no virus was detected by PCR. These bats might be a reservoir for Ebola or Ebola-like viruses, and extend the range of filoviruses to ...
Maan Harjeet Singh - - 2013
Nonpolio acute flaccid paralysis is increasing in India. To determine viral causes, we conducted cell culture and molecular analysis identification of nonpolio human enteroviruses associated with acute flaccid paralysis during March-August 2010 in northern India. The predominant nonpolio enterovirus found was echovirus 13, a serotype rarely isolated in India.
Parden Alison M - - 2013
To assess stress urinary incontinence (SUI) and other lower urinary tract symptom outcomes in women undergoing repeat midurethral sling procedures compared with those undergoing primary midurethral sling procedures. Cure was defined as responses of "not at all" or "somewhat" to both questions of the SUI subscale of the Urogenital Distress ...
Yu Qi - - 2013
To determine risk for avian influenza virus infection, we conducted serologic surveillance for H5 and H9 subtypes among poultry workers in Beijing, China, 2009-2010, and assessed workers' understanding of avian influenza. We found that poultry workers had considerable risk for infection with H9 subtypes. Increasing their knowledge could prevent future ...
Silverman Michael A - - 2013
We describe the clinical, laboratory, and radiographic characteristics of 15 cases of eastern equine encephalitis in children during 1970-2010. The most common clinical and laboratory features were fever, headache, seizures, peripheral leukocytosis, and cerebrospinal fluid neutrophilic pleocytosis. Radiographic lesions were found in the basal ganglia, thalami, and cerebral cortex. Clinical ...
Minetti Andrea - - 2013
Despite high reported coverage for routine and supplementary immunization, in 2010 in Malawi, a large measles outbreak occurred that comprised 134,000 cases and 304 deaths. Although the highest attack rates were for young children (2.3%, 7.6%, and 4.5% for children <6, 6-8, and 9-11 months, respectively), persons >15 years of ...
Tognotti Eugenia - - 2013
In the new millennium, the centuries-old strategy of quarantine is becoming a powerful component of the public health response to emerging and reemerging infectious diseases. During the 2003 pandemic of severe acute respiratory syndrome, the use of quarantine, border controls, contact tracing, and surveillance proved effective in containing the global ...
Ramos José M - - 2013
Human infection with Rickettsia sibirica mongolitimonae was initially reported in 1996, and reports of a total of 18 cases have been published. We describe 6 additional cases that occurred in the Mediterranean coast region of Spain during 2007-2011. Clinicians should consider this infection in patients who have traveled to this ...
Kasabi Gudadappa S - - 2013
To determine the cause of the recent upsurge in Kyasanur Forest disease, we investigated the outbreak that occurred during December 2011-March 2012 in India. Male patients >14 years of age were most commonly affected. Although vaccination is the key strategy for preventing disease, vaccine for boosters was unavailable during 2011, ...
Pattyn Nele - - 2013
Numerous meta-analyses have investigated the effect of exercise in different populations and for single cardiovascular risk factors, but none have specifically focused on the metabolic syndrome (MetS) patients and the concomitant effect of exercise on all associated cardiovascular risk factors. The aim of this article was to perform a systematic ...
Brandt Kathleen R - - 2013
This study evaluated digital breast tomosynthesis (DBT) as an alternative to conventional diagnostic mammography in the workup of noncalcified findings recalled from screening mammography in a simulated clinical setting that incorporated comparison mammograms and breast ultrasound results. One hundred forty-six women, with 158 abnormalities, underwent diagnostic mammography and two-view DBT. ...
Shah Sumit P - - 2013
To use spectral domain optical coherence tomography-guided duration of facedown positioning to study anatomical macular hole closure rates. Retrospective review of patients with macular holes undergoing 23-gauge pars plana vitrectomy and intraocular gas tamponade. Spectral domain optical coherence tomography imaging was done on postoperative Day 1. Patients remained facedown for ...
Fält Tobias - - 2013
The purpose of this study was to evaluate an abdominal CT protocol in which radiation dose was reduced and i.v. contrast dose increased for young patients and radiation dose was increased and i.v. medium dose decreased for elderly patients. The hypothesis was that these adjustments would result in constant image ...
Drubach Laura A - - 2013
The purpose of our study was to correlate the results of the radionuclide salivagram with the corresponding chest radiography findings on patients being evaluated for salivary aspiration to determine the utility of the salivagram. We identified 222 patients younger than 21 years who underwent salivagram and chest radiography within 3 ...
Tudela Carmen M - - 2013
To estimate the effect of body mass index (BMI) on magnesium levels for eclampsia prophylaxis. This is a retrospective study from 2004 to 2011, examining magnesium levels in women receiving seizure prophylaxis. Women received 6 g and then 2 g/h. Women had 4-hour and 12-hour levels drawn. Levels were considered ...
Wilson Barbara - - 2013
Magnet-designated and aspiring hospitals use research and evidence-based practice initiatives to demonstrate new knowledge and innovation, a key component of the Magnet Recognition Program. Four creative approaches to supporting and conducting institutional nursing research and the implementation of evidence-based care are illustrated, along with examples of successful nurse staff-led projects.
Dong Zhihui - - 2013
To present the short- to midterm outcomes after management of 14 patients with symptomatic isolated dissection of superior mesenteric artery (SIDSMA) and propose a preliminary treatment algorithm. SIDSMA is a rare but potentially fatal entity. However, most of these reports were isolated case reports, and a consensus treatment protocol remains ...
Miller Seth M SM Department of Radiation Oncology & Laboratory of Nano- & Translational Medicine, University of North Carolina, Chapel Hil, NC, - - 2013
Chemoradiotherapy, the concurrent administration of chemotherapy and radiotherapy, is a treatment paradigm in oncology. It is part of the standard of care and curative treatment of many cancers. Given its importance, one of the primary goals of cancer research has been to identify agents and/or strategies that can improve the ...
Medina-Kauwe Lali K LK Department of Biomedical Sciences, Cedars-Sinai Medical Center, Geffen School of Medicine, University of California Los Angeles, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA. - - 2013
The outer shell of the adenovirus capsid comprises three major types of protein (hexon, penton base and fiber) that perform the majority of functions facilitating the early stages of adenovirus infection. These stages include initial cell-surface binding followed by receptor-mediated endocytosis, endosomal penetration and cytosolic entry, and intracellular trafficking toward ...
Amoretti Nicolas N Department of Radiology, Centre Hospitalo-Universitaire de Nice, Hôpital Archet 2, 151, Rte Saint-Antoine de Ginestière, 06200 Nice, France. - - 2013
The aim of this study was to evaluate CT- and fluoroscopy-guided percutaneous screw fixation by radiologists in the management of acetabular roof fractures. Fifty-two consecutive adult patients with a nondisplaced and isolated acetabular roof fracture were prospectively treated by an interventional radiologist who made a percutaneous screw fixation under CT ...
Chen Foster F National Institutes of Health, Bethesda, MD 20892-1150, - - 2013
This study was performed to determine (1) the incidence of humeral shaft fractures within the Medicare noncancer population, (2) the trends in utilization of humeral shaft fixation techniques by plate-and-screw devices and intramedullary nails, (3) differences in procedure times, and (4) the outcomes of individuals as measured by rate of ...
Coppola Stefano S Department of Molecular Medicine, 'Sapienza' University of Rome, Viale Regina Elena, 324, 00161, Rome, - - 2013
Lipid-mediated delivery of DNA is hindered by extracellular and intracellular barriers that significantly reduce the transfection efficiency of synthetic nonviral vectors. In this study we investigated the role of the actin and microtubule networks on the uptake and cytoplasmic transport of multicomponent cationic liposome-DNA complexes in CHO-K1 live cells by ...
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