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Pbert Lori L Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA. - - 2013
Models are needed for implementing weight management interventions for adolescents through readily accessible venues. This study evaluated the feasibility and efficacy of a school nurse-delivered intervention in improving diet and activity and reducing body mass index (BMI) among overweight and obese adolescents. Six high schools were randomized to either a ...
Odum Mary M Texas A&M University, 4243 TAMU, College Station, TX 77843, USA. - - 2013
Researchers in numerous disciplines have investigated the effects of the school environment on childhood obesity (CHO), one of the greatest current health concerns in the United States. There is a gap in current empirical evidence, however, on school personnel's perspectives of this issue. This study examined school personnel's perceptions of ...
Davis Sally M SM Prevention Research Center, University of New Mexico, 1 University of New Mexico, MSC 11 6145, Albuquerque, NM 87131, USA. - - 2013
Obesity is a major concern among American Indians and Hispanics. The Child Health Initiative for Lifelong Eating and Exercise (CHILE) is an evidence-based intervention to prevent obesity in children enrolled in 16 Head Start (HS) Centers in rural communities. The design and implementation of CHILE are described. CHILE uses a ...
Lee Hedwig H Department of Sociology, University of Washington, 211 Savery Hall, Box 353340, Seattle, WA 98195-3340, USA. - - 2013
The rise in adolescent obesity has become a public health concern, especially because of its impact on disadvantaged youth. This article examines the role of disadvantage at the family-, peer-, school-, and neighborhood-level, to determine which contexts are related to obesity in adolescence and young adulthood. We analyzed longitudinal data ...
Moreno Geraldine G Oregon Research Institute, PO Box 1715, Franklin Blvd., Eugene, OR 97403, USA. - - 2013
The high rates of childhood overweight and obesity in the United States have generated interest in schools as sites for monitoring body mass index (BMI) information. This study established baseline values for a 5-year longitudinal assessment of BMI of elementary school children and examined variation across the schools, because little ...
Benowitz Neal L NL Department of Medicine, Bioengineering and Therapeutic Sciences, Division of Clinical Pharmacology and Experimental Therapeutics, University of California, San Francisco, California 94143-1220, USA. - - 2013
Bupropion, an antidepressant and smoking cessation medication, is metabolized to hydroxybupropion (HB), an active metabolite, primarily by CYP2B6. To compare plasma concentrations of bupropion and metabolites at steady state in healthy volunteers with and without CYP2B6 genetic variants. In a genotype-guided study of 42 healthy individuals, we measured the plasma ...
Mangialasche F F Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. - - 2013
The aim of this study was to evaluate the accuracy of combined structural magnetic resonance imaging (MRI) measures and plasma levels of vitamin E forms, including all eight natural vitamin E congeners (four tocopherols and four tocotrienols) and markers of vitamin E oxidative/nitrosative damage, in differentiating individuals with Alzheimer's disease ...
RosiƄska Magdalena M National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland. - - 2013
To gain insight into HIV transmission we estimated the proportion of those recently infected. We examined data from HIV-positive patients and a random 10% sample of HIV-negative patients tested at Voluntary Counseling and Testing sites in Poland in 2006. Archived samples from positive patients were tested by three assays to ...
Grewal Yadveer S YS Centre for Biomarker Research and Development, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, - - 2013
Inexpensive, simple and quick detection of pathogen antigens in human samples is a key global health objective. Limiting factors include the cost and complexity of diagnostic tests that utilize antibody probes. Herein, we present a method for label-free electrochemical detection of a protein from the enteric pathogen Entamoeba histolytica using ...
Garner Amanda L AL Department of Chemistry, The Skaggs Institute for Chemical Biology and The Worm Institute for Research and Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, - - 2013
As a guide for chemical probe design, focused analogue synthetic studies were undertaken upon the lactone ring of 3-oxo-C(12)-homoserine lactone. We have concluded that hydrolytic instability of the heterocyclic ring is pivotal for its ability to modulate immune signaling and probe preparation was aligned with these findings.
Su Pin-Chuan PC Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, - - 2013
Obtaining high yields of membrane proteins necessary to perform detailed structural study is difficult due to poor solubility and variability in yields from heterologous expression systems. To address this issue, an Escherichia coli-based membrane protein overexpression system utilizing an engineered bacterial outer membrane protein F (pOmpF) fusion has been developed. ...
Bauman Joseph D JD Center for Advanced Biotechnology and Medicine, Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey, United - - 2013
HIV-1 reverse transcriptase (RT) undergoes a series of conformational changes during viral replication and is a central target for antiretroviral therapy. The intrinsic flexibility of RT can provide novel allosteric sites for inhibition. Crystals of RT that diffract X-rays to better than 2 Å resolution facilitated the probing of RT ...
Mukome Fungai N D FN Department of Land, Air and Water Resources and ‡Department of Plant Sciences, University of California Davis, Davis, California 95616, United - - 2013
Studies have shown that pyrolysis method and temperature are the key factors influencing biochar chemical and physical properties; however, information on the nature of biochar feedstocks is more accessible to consumers, making feedstock a better measure for selecting biochars. This study characterizes physical and chemical properties of commercially available biochars ...
Kim Wantae - - 2013
Wnt/β-catenin signalling plays essential roles in embryonic development as well as tissue homoeostasis in adults. Thus abnormal regulation of Wnt/β-catenin signalling is linked to a variety of human diseases, including cancer, osteoporosis and Alzheimer's disease. Owing to the importance of Wnt signalling in a wide range of biological fields, a ...
Graves Lee M LM The Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. - - 2013
Recent advances in proteomics have facilitated the analysis of the kinome 'en masse'. What these studies have revealed is a surprisingly dynamic network of kinase responses to highly selective kinase inhibitors, thereby illustrating the complex biological responses to these small molecules. Moreover these studies have identified key transcription factors, such ...
McDonald Ashley Ringer AR Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, - - 2013
Base stacking is known to make an important contribution to the stability of DNA and RNA, and accordingly, significant efforts are ongoing to calculate stacking energies using ab initio quantum mechanical methods. To date, impressive improvements have been made in the model chemistries used to perform stacking energy calculations, including ...
Karns Kelly K San Francisco Graduate Program in Bioengineering, University of California, Berkeley, California 94720, - - 2013
Riboswitches are RNA sensors that change conformation upon binding small molecule metabolites, in turn modulating gene expression. Our understanding of riboswitch regulatory function would be accelerated by a high-throughput, quantitative screening tool capable of measuring riboswitch-ligand binding. We introduce a microfluidic mobility shift assay that enables precise and rapid quantitation ...
Bischof Janet - - 2013
ABSTRACT: Advanced practice nurses (APNs) have a responsibility to share information from projects and research with other professionals. Poster presentations offer a way to visually share the information to a wide audience. Key elements include title, objective/purpose, data collection, results, analysis, implications for nursing, and appropriate references.
Dokken Betsy B - - 2013
ABSTRACT: Primary care providers offer diabetes care for many patients in the United States. Primary care nurse practitioners can benefit from an understanding of effective administration of insulin therapy. This review will outline suggestions for the effective use of insulin analogues in clinical practice.
Avital-Shmilovici Michal M Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, - - 2013
Efficient total synthesis of insulin is important to enable the application of medicinal chemistry to the optimization of the properties of this important protein molecule. Recently we described "ester insulin"--a novel form of insulin in which the function of the 35 residue C-peptide of proinsulin is replaced by a single ...
Rodríguez Laura P LP Universidad de Santiago de Compostela, Departamento de Farmacología, Facultad de Veterinaria, 27002 Lugo, - - 2013
Biologically active macrocycles containing a cyclic imine were isolated for the first time from aquaculture sites in Nova Scotia, Canada, during the 1990s. These compounds display a "fast-acting" toxicity in the traditional mouse bioassay for lipophilic marine toxins. Our work aimed at developing a receptor-based detection method for spirolides using ...
Burghardt Thomas P TP Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, MN 55905, USA. - - 2013
Myosin is the chemomechanical energy transducer in striated heart muscle. The myosin cross-bridge applies impulsive force to actin while consuming ATP chemical energy to propel myosin thick filaments relative to actin thin filaments in the fiber. Transduction begins with ATP hydrolysis in the cross-bridge driving rotary movement of a lever ...
Hoffman Laurel L The Department of Neurobiology and Anatomy, The University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, - - 2013
Calcium-calmodulin-dependent protein kinase II (CaMKII) has been implicated in a wide variety of cellular processes, which include a critical regulatory role in actin cytoskeletal assembly. CaMKII is ubiquitous in cells, expressed as one of four isoforms termed α, β, γ, and δ. Characterization of the CaMKII-actin interaction has mainly focused ...
Slater Louise H LH Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, - - 2013
Studying how pathogens subvert the host to cause disease has contributed to the understanding of fundamental cell biology. Bacillus anthracis, the causative agent of anthrax, produces the virulence factor lethal toxin to disarm host immunity and cause pathology. We conducted a phenotypic small molecule screen to identify inhibitors of lethal ...
Shah Lubdha M - - 2013
Intracranial hypotension is an uncommon cause of headaches that is often misdiagnosed. The classic MRI features of intracranial hypotension can be variable and subjective. The purpose of this study was to provide objective criteria in the MRI evaluation of intracranial hypotension by quantifying normal values for the pontomesencephalic angle, mamillopontine ...
Feng Jiaxuan - - 2013
Stent graft-induced distal redissection (SIDR) is one of the major concerns in the durability of endovascular repair for complicated Stanford type B aortic dissection. The characteristics and means of prevention of this complication remain unknown. From April 1997 to March 2010, 674 patients with type B aortic dissections were treated ...
Sieswerda Simkje - - 2013
Cognitive models explain extreme thoughts, affects, and behaviors of patients with Borderline Personality Disorder (BPD) by specific mal-adaptive schemas and dichotomous thinking. Psychodynamic theories ascribe these to splitting. This study expanded the study of Veen and Arntz (2000) and investigated whether extreme evaluations in BPD are (1) dichotomous, negativistic, or ...
Roxanas Milton - - 2013
OBJECTIVE: The purpose of this paper was to consider the life and contribution of Professor William Siegfried Dawson (1891-1975) by examination of school, university and hospital reports and journal articles. CONCLUSIONS: Professor Dawson made a major contribution, through his academic and professional roles and leadership, to the firm establishment of ...
Cheng Zhuo - - 2013
Type B aortic dissection can be acutely complicated by rapid expansion, rupture, and malperfusion syndromes. Short-term adverse outcomes are associated with failure of the false lumen to thrombose. The reasons behind false lumen patency are poorly understood, and the objective of this pilot study was to use computational fluid dynamics ...
Moul Caroline - - 2013
In accordance with a recently proposed account of amygdala function in psychopathy, it is hypothesized that people with high levels of psychopathic personality traits have a bias in learning style to encode the general valence, and neglect the specific-features, of an outcome. We present a novel learning task designed to ...
Gallotti Anna - - 2013
The objective of our study was to evaluate the MDCT features of incidentally detected neuroendocrine tumors (NETs) of the pancreas, identify features that can predict tumor biology or aggressiveness and long-term outcome, and determine the incidence of "nonbenign" behavior. In this retrospective study, 60 histologically verified pancreatic NETs incidentally detected ...
Adams Jeffrey M - - 2013
This department highlights nursing leaders who have demonstrated a commitment to innovation and patient care leadership in practice, policy, research, education and theory. This interview profiles Terry Fulmer, PhD, RN, FAAN, chairperson of the Robert Wood Johnson Executive Nurse Fellows Advisory Committee and dean of the Bouvé College of Health ...
Erkoç Mustafa Fatih - - 2013
Hearing loss (HL) is common in patients with chronic renal failure (CRF), but its cause is controversial. The aim of this study was to determine the effect of CRF on the bone density of the otic capsule using densitometric measurements with MDCT and to evaluate the relationship between changes in ...
Kaplan Robert M - - 2013
OBJECTIVE: A movie on malariotherapy for neurosyphilis made at Mont Park and filmed by Reg Ellery in 1926 is believed to be the oldest surviving movie of psychiatric treatment in Australia. The objective is to review the movie and discuss the background and context of the film, which shows the ...
Sloan Kenneth B - - 2013
We have identified, for any surrogate membrane and human skin in vitro, the maximum flux through the membrane (output) should be measured if a correlation between the two is to be obtained. We also identified from an analysis of the passive permeation process that molecular weight, lipid and aqueous solubilities ...
Stuart Jourdan E - - 2013
: To examine factors associated with discontinuation of the oral contraceptive pill (OCP), patch, and ring. : We included 1,452 female participants from the Contraceptive CHOICE Project who selected the OCP, patch, or ring and completed 12 months of follow-up for this analysis. We defined discontinuation as stopping the contraceptive ...
Boroczky Lilla - - 2013
The purpose of this article is to evaluate the performance of radiologists using a prototype clinical decision support system to diagnose and manage patients with breast cancer based on dynamic contrast-enhanced MRI studies. The study was conducted with three breast radiologists and two breast imaging fellows who gave patient treatment ...
Machida Haruhiko - - 2013
The purpose of this study was to investigate the utility of model-based iterative reconstruction (MBIR) for improving delineation of the anterior spinal artery (ASA) during routine-dose CT angiography. For imaging of 10 patients (six men, four women; mean age, 73.9 ± 7.5 years) consecutively undergoing CT angiography of the whole ...
Gibbins Karen J - - 2013
: Clinical trials support the efficacy and safety of magnesium sulfate for cerebral palsy prevention. We evaluated the implementation of a clinical protocol for the use of magnesium for cerebral palsy prevention in our large women's hospital, focusing on uptake, indications, and safety. : We performed a review of selected ...
Barrera Juan Guillermo - - 2013
The optimal management of patients with combined carotid and coronary artery disease requiring cardiac surgery is still unknown. Staged carotid endarterectomy and carotid artery stenting (CAS), each followed by coronary artery bypass graft (CABG), are options frequently employed. However, for patients with severe carotid artery disease in urgent need of ...
Teefey Sharlene A - - 2013
The purpose of our study was to determine, first, if gallbladder wall striations in patients with sonographic findings suspicious for acute cholecystitis are associated with gangrenous changes and certain histologic features; and, second, if WBC count or other sonographic findings are associated with gangrenous cholecystitis. Sixty-eight patients who underwent cholecystectomies ...
Shirey Maria R - - 2013
This department highlights change management strategies that may be successful in strategically planning and executing organizational change initiatives. With the goal of presenting practical approaches helpful to nurse leaders advancing organizational change, content includes evidence-based projects, tools, and resources that mobilize and sustain organizational change initiatives. In this article, the ...
Lobato Armando C - - 2013
To ascertain midterm outcomes of the sandwich technique (ST) for internal iliac artery endorevascularization (ER). All consecutive patients with complex aortoiliac aneurysms, isolated common iliac artery aneurysms, and abdominal aortic aneurysms with bilateral short, nondiseased common iliac artery undergoing elective endovascular aneurysm repair (EVAR) with the ST at our center, ...
Domes Gregor - - 2013
Previous studies associated psychopathy in adults with deficits in empathy but these studies did not directly compare cognitive and emotional facets of empathy. The present study sought to establish whether psychopathy is associated with impairments in emotional empathy among adult offenders. Participants were 90 male offenders scoring low (n = ...
Froemming Adam T - - 2013
The purpose of this study was to describe the imaging features of renal epithelioid angiomyolipoma (EAML), a rare subtype of angiomyolipoma, with clinical and pathologic correlation. This study was a retrospective review of nine cases from a single institution in which total resection and preoperative imaging were performed and the ...
Ziech Manon L W - - 2013
The objective of our study was to perform a semiquantitative analysis of dynamic contrast-enhanced MRI for the evaluation of disease activity and therapeutic response in patients with perianal fistulizing Crohn disease. Sixteen consecutively registered patients with perianal Crohn disease underwent pelvic MRI. A dynamic contrast-enhanced sequence was performed at 3 ...
Zebede Salomon - - 2013
: To report on anatomical and functional outcomes, patient satisfaction, and associated morbidity and mortality in patients undergoing LeFort colpocleisis. : This was a retrospective case series of LeFort colpocleisis performed from January 2000 to October 2011. Data obtained from a urogynecologic database included demographics, comorbidities, medications, and urinary and ...
- - 2013
Abstracts or summaries of online content are printed in every issue of Obstetrics & Gynecology in this section. The complete documents can be found on our web site, www.greenjournal.org. The specific URL for the content in this section is printed at the end of the abstract or summary.
Landolfi Emilio - - 2013
This article examines the nature of exercise addiction. It presents a broad, congruent and discerning narrative literature review with the aim of providing a deeper understanding of the condition 'exercise addiction', including symptoms and options for treatment. In addition, guidelines are provided with respect to 'healthy' levels of exercise. Criteria ...
Atwell Thomas D - - 2013
The purpose of this article is to compare the efficacy and complication rates of percutaneous radiofrequency ablation (RFA) and cryoablation in the treatment of renal masses measuring 3.0 cm and smaller. A retrospective review was performed of 385 patients with 445 tumors measuring 3.0 cm or smaller treated with thermal ...
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