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Buzás Péter - - 2013
Most nonprimate mammals possess dichromatic ("red-green color blind") color vision based on short-wavelength-sensitive (S) and medium/long-wavelength-sensitive (ML) cone photoreceptor classes. However, the neural pathways carrying signals underlying the primitive "blue-yellow" axis of color vision in nonprimate mammals are largely unexplored. Here, we have characterized a population of color opponent (blue-ON) ...
Goadsby Peter J - - 2013
In general neurologic practice, you would have seen a patient with migraine today, who would have described the problem, and almost certainly listed triggers for the attacks. So what happens when triggering is tested systematically, and what can we learn?
Mina Rina - - 2013
OBJECTIVES: This study tested the concurrent validity of the systemic lupus erythematosus responder index (SRI) in assessing improvement in juvenile-onset systemic lupus erythematosus (jSLE). METHODS: The SRI considers changes in the SELENA-SLEDAI, BILAG and a 3-cm visual analogue scale of physician-rated disease activity (PGA) to determine patient improvement. Using prospectively ...
Johannessen Christian - - 2013
The Raman Optical Activity (ROA) spectra of both enantiomers of 2-Br-hexahelicene in chloroform solution have been measured in the range 1700-300 cm-1. Density Functional Theory (DFT) calculations accurately reproduce the observed features. The most intense ROA features are also the most intense Raman features, in the region 1350-1400 cm-1, and ...
Kim Ki Tae - - 2013
A 6-mer oligonucleotide containing a fluorescent moiety has been used as a novel fluorescent probe for the 3'-overhang of telomeric DNA based on competition between non-fluorescent tetramolecular and fluorescent (3+1) intermolecular G-quadruplexes.
Berry D P - - 2013
Increasing food production for the growing human population off a constraining land-base will require greater efficiency of production. Genetic improvement of feed efficiency in cattle, which is cumulative and permanent, is one likely vehicle to achieving efficiency gains. The objective of this review is to summarize genetic parameters for feed ...
Hoskote Sumedh S - - 2013
Whipple disease is a disorder caused by Tropheryma whipplei, a ubiquitous Gram-positive bacillus. In addition to gastrointestinal manifestations, many other systems may be involved in Whipple disease. Pulmonary hypertension (PH) is a rare manifestation of Whipple disease, and its clinical course is not well established. We report a case of ...
Basu Subhashis - - 2013
AIM: To improve the detection and quality of care of patients who attend the emergency department (ED) with confirmed or suspected domestic abuse (DA). DESIGN: A quality improvement report on the design, implementation and evaluation of a specialised service and structured training programme to detect and manage DA presentations within ...
Chang Hung - - 2013
Patients with acute promyelocytic leukemia (APL) are prone to both bleeding and thrombosis. The bleeding complications are well known. In contrast, APL-associated thrombosis is relatively underappreciated. We aimed to explore the issue of APL-associated thrombosis events. In the past 20 years, 127 cases with APL were found in our hospital ...
Ramirez-Amaya Victor - - 2013
After spatial exploration in rats, Arc mRNA is expressed in ∼2% of dentate gyrus (DG) granule cells, and this proportion of Arc-positive neurons remains stable for ∼8 h. This long-term presence of Arc mRNA following behavior is not observed in hippocampal CA1 pyramidal cells. We report here that in rats ...
Qian Haifeng - - 2013
Imazethapyr (IM) is a chiral herbicide with reported enantioselective biological activities between two of its enantiomers. This report investigated the effect of enantioselectivity between R- and S-IM in Arabidopsis thaliana on chlorophyll synthesis and photosynthesis. The results suggest that R-IM inhibited the transcription of chlM to a greater extent than ...
Zhao Zengxiang - - 2013
Easy PC: α-Hydroxy phosphonates were synthesized by copper/tert-butyl hydroperoxide (TBHP)-catalyzed oxidative addition reactions of H-phosphonates with alcohols or ethers. Diverse α-hydroxy phosphonates were obtained from substituted benzyl alcohols or alkyl alcohols and alkyl ethers in moderate to good yields.
Dadheech Nidheesh - - 2013
Pluripotency and Stemness is believed to be associated with high Oct-3/4, Nanog, and Sox-2 (ONS) expression. Alike Embryonic Stem (ES) cells, high ONS expression eventually became the measure of pluripotency in any cell. The threshold expression of ONS genes that underscores pluripotency, stemness and differentiation potential is still unclear. Therefore, ...
White Harvey - - 2013
Acute coronary syndrome (ACS) encompasses a spectrum of diseases, ranging from ST-elevation myocardial infarction to non-ST-elevation myocardial infarction and unstable angina. A key initiating event in the pathology of ACS is atheromatous plaque disruption, in which the exposure of thrombogenic material triggers simultaneous activation of primary and secondary hemostatic pathways. ...
Angelova Polina - - 2013
Penta(tert-butylthio)corannulene and penta(4-dimethylaminophenylthio)corannulene form highly stable monolayers on gold surfaces, as indicated by X-ray photoelectron spectroscopy (XPS). Formation of these homogeneous monolayers involves multivalent coordination of the five sulfur atoms to gold with the peripheral alkyl or aryl substituents pointing away from the surface. No dissociation of C-S bonds upon ...
Murray Rebecca - - 2013
The acute inhibitory effects of parathyroid hormone (PTH) on proximal tubule Na(+)-K(+) ATPase (Na-K) and sodium-dependent phosphate (Na-Pi) transport have been extensively studied, while little is known about the chronic effects of PTH. Patients with primary hyperparathyroidism, a condition characterized by chronic elevations in PTH, exhibit persistent hypophosphatemia but not ...
Seo Hyowon - - 2013
The enantioselective synthesis of 7-epi-incarvilline for formal syntheses of (-)-incarvilline, (+)-incarvine C, and (-)-incarvillateine is described. The key features of our synthesis involve (1) stereoselective construction of the optically active bicyclic lactone utilizing Pd(0)-catalyzed allylic alkylation, (2) efficient transformation of the bridged bicyclic lactone to the key bicyclic lactam skeleton, ...
Rosen Ronald - - 2013
Abstract ABSTRACT: The objectives of this study were to describe: (1) the osmotic environment and precise location of the redia in the snail intermediate host, (2) where retraction of the distome body into the cercarial tail occurs, and (3) the subsequent emergence path of the cercaria out of the snail. ...
Lafranca Jeffrey A - - 2013
In this era of organ donor shortage, live kidney donation has been proven to increase the donor pool; however, it is extremely important to make careful decisions in the selection of possible live donors. A body mass index (BMI) above 35 is generally considered as a relative contraindication for donation. ...
Gold Robert S - - 2013
Among the most memorable lessons I learned from my father was based on a comment he often made when I was young: "The days are long and the years are short." During a year as President of the Society for Public Health Education (SOPHE), there were many days that seemed ...
Hsu Chien - - 2013
The influence of temperature on the electrophoretic behavior of a charge-regulated zwitterionic particle is investigated by considering a spherical SiO2 particle in an aqueous NaCl solution of concentration CNaCl with its pH adjusted by NaOH and HCl as an example. A complete mobility-pH-temperature plot and a mobility-CNaCl-temperature plot are prepared ...
Lord Richard L - - 2013
A computational approach for calculating the distortions in the lowest energy triplet metal to ligand charge-transfer ((3)MLCT = T(0)) excited states of ruthenium(II)-bipyridine (Ru-bpy) complexes is used to account for the patterns of large variations in vibronic sideband amplitudes found in the experimental 77 K emission spectra of complexes with ...
Fuertes Silvia - - 2013
PURPOSE: Interim (18)F-FDG PET performed early during the course of therapy in diffuse large B-cell lymphoma (DLBCL) is a good predictor of outcome. However, interpretation criteria for interim PET for the evaluation of tumour response are still not clearly defined. The study aim was to assess whether interim PET can ...
Kamboj Jasmine - - 2013
Acyclovir is used for its potent antiviral properties for the mucocutaneous herpes, herpes zoster, herpes encephalitis, and genital herpes simplex. The drug has a very wide distribution involving almost every organ of the body, with excretion into the urine. Urine analysis, kidney function, liver function, and complete blood counts are ...
Laghaei Rozita - - 2013
We study via all atom classical molecular dynamics (MD) simulation the process of uptake of ferrous ions (Fe(2+) ) into the human ferritin protein and the catalytic ferroxidase sites via pores ("channels") in the interior of the protein. We observe that the 3-fold hydrophilic channels serve as the main entrance ...
Shi Ying - - 2013
Understanding the neural representation of limb position is important for comprehending the control of limb movements and the maintenance of body schema, as well as for the development of neuroprosthetic systems designed to replace lost limb function. Multiple subcortical and cortical areas contribute to this representation but its multimodal basis ...
Nácher-Mestre Jaime - - 2013
This article describes the development, validation and application of a rapid screening method for the detection and identification of undesirable organic compounds in aquaculture products. A generic sample treatment was applied without any purification or preconcentration step. After extracting the samples with acetonitrile/water 80:20 (0.1% formic acid), the extracts were ...
Hakky Michael M - - 2013
BACKGROUND: Medial lemniscus T2 hyperintensity (MLH) has been recently demonstrated as potential imaging marker for small vessel disease (SVD). Our purpose in this study is to improve accuracy of regions of interest (ROI) analysis for this imaging finding. METHODS AND METHODS: Two neuroradiologists retrospectively reviewed 103 consecutive outpatient brain MRI. ...
Moran Kevin - - 2013
From 2007-2012, New Zealand lifeguards provided first aid to almost 9,000 beachgoers, an average of 1,772 cases per annum; more than the average number of rescues (n = 1,343) each year. This study describes the aetiology of non-drowning related injuries occurring at surf beaches patrolled by lifeguards. The study design ...
Pientong Chamsai - - 2013
ABSTRACT: BACKGROUND: The variation of human papillomavirus (HPV) genes or HPV variants demonstrates different risks of cervical cancer. Mutation in the long control region (LCR) at YY1-motifs is one of the mechanisms for enhancing viral oncogene expression during the course of cancer cell progression. In Thai women, cervical cancers are ...
Chung Elena - - 2013
Blood pressure monitoring has come a long way from the initial observations made by Reverend Hales in the 18th century. There are none that deny the importance of monitoring perioperative blood pressure; however, the limited ability of the current prevalent technology (oscillometric blood pressure monitoring) to offer continuous blood pressure ...
Adde Lars - - 2013
This study evaluates the role of postterm age at assessment and the use of one or two video recordings for the detection of fidgety movements (FMs) and prediction of cerebral palsy (CP) using computer vision software. Recordings between 9 and 17 weeks postterm age from 52 preterm and term infants ...
Xiong Jiang - - 2013
ABSTRACT: BACKGROUND: The aim of this study was to determine the early mortality and major complications of acute complicated type B aortic dissection (ACBD) after thoracic endovascular aortic repair (TEVAR). METHODS: Twenty-six consecutive patients with ACBD who underwent TEVAR were included. Clinical indications before TEVAR and in-hospital mortality and major ...
Xu Xin-Rong - - 2013
We theoretically investigate the electronic transport between quantum Hall states and quantum anomalous Hall states in a zigzag edged graphene nanoribbon based two-terminal heterojunction. The electrical conductance of the system is calculated by the method of the non-equilibrium Green's function and Landauer-Büttiker formula. We find perfect transmission through the junction ...
Neiman Tal - - 2013
In free operant experiments, subjects alternate at will between targets that yield rewards stochastically. Behavior in these experiments is typically characterized by (1) an exponential distribution of stay durations, (2) matching of the relative time spent at a target to its relative share of the total number of rewards, and ...
Restivo Domenico A - - 2013
OBJECTIVES: This study looked at the effect of botulinum toxin type A (BoTox-A) in patients with amyotrophic lateral sclerosis (ALS) with dysphagia due to isolated upper motor neuron (UMN) involvement or combined UMN/lower motor neuron (LMN) impairment associated with oral phase or oropharyngeal muscles involvement. Establishing whether different pathophysiologic mechanisms ...
Gallego-Escuredo José M - - 2013
BACKGROUND: Facial lipoatrophy, a common alteration among HIV-1-infected, antiretroviral-treated patients, is often corrected using autologous transplantation. In some cases, especially when enlarged adipose tissue from the dorso-cervical area (i.e. a "buffalo hump") is used as a source of fat for transplantation, the transplanted fat develops progressive hypertrophy. To gain insight ...
Marada Adinarayana - - 2013
Despite the growing evidence of the role of oxidative stress in diseases, its molecular mechanism of action remains poorly understood. Yeast Saccharomyces cerevisiae provides a valuable model system to elucidate the effects of oxidative stress on mitochondria in higher eukaryotes. Dimeric yeast Mge1, the cochaperone of Heat shock protein 70 ...
Payez Atefeh - - 2013
There is a large body of experimental data demonstrating various effects of magnetic field (MF) on plants growth and development. Although the mechanism(s) of perception of MF by plants is not yet elucidated, there is a possibility that like other stimuli, MF exerts its effects on plants by changing membrane ...
Dimasi Joseph A - - 2013
The R&D productivity of pharmaceutical firms has become an increasingly significant concern of industry, regulators, and policymakers. To address an important aspect of R&D performance, public and private data sources were used to estimate clinical phase transition and clinical approval probabilities for the pipelines of the 50 largest pharmaceutical firms ...
Tai Chih-I - - 2013
Activation of signal transducer and activator of transcription 3 (Stat3) by leukemia inhibitory factor (LIF) maintains mouse embryonic stem cell (mESC) self-renewal and also facilitates reprogramming to ground state pluripotency. Exactly how LIF/Stat3 signaling exerts these effects, however, remains elusive. Here, we identified gastrulation brain homeobox 2 (Gbx2) as a ...
Sharma Naveen - - 2013
T cells produce a number of cytokines and chemokines upon stimulation with TLR agonists in the presence or absence of TCR signals. Here, we show that secretion of neutrophil chemoattractant CXCL8 from human T cell line Jurkat in response to stimulation with TLR agonists is reduced when cell stimulation is ...
van der Kooij Katinka - - 2013
Does the nervous system continuously realign the senses so that objects are seen and felt in the same place? Conflicting answers to this question have been given. Research imposing a sensory mismatch has provided evidence that the nervous system realigns the senses to reduce the mismatch. Other studies have shown ...
Smith Stacy - - 2013
OBJECTIVES: To assess whether mortality of patients admitted on weekends and public holidays was higher in a district general hospital whose consultants are present more than 6 h per day on the acute medical unit with no other fixed clinical commitments. DESIGN: Cohort study. SETTING: Secondary care. PARTICIPANTS: All emergency ...
Baradel Nathalie - - 2013
Polymers that toe the line: Well-defined linear polystyrene chains containing precisely positioned hexose moieties (mannose, galactose, and N-acetylglucosamine) were synthesized by a sequence-controlled polymerization approach followed by a series of site-selective modification steps. Such multifunctional single-chain hexose arrays associate specifically with complementary lectins.
Holschneider Daniel P - - 2013
We explored whether cerebral cortical impact injury (CCI) effects extend beyond direct lesion sites to affect remote brain networks, and whether acetylcholinesterase (AChE) inhibition elicits discrete changes in functional activation of motor circuits following CCI. Adult, male rats underwent unilateral motor-sensory CCI or sham injury. Physostigmine (AChE inhibitor) or saline ...
Feelders Richard A - - 2013
Context:Cushing's disease (CD) is associated with serious morbidity and, when suboptimally treated, an increased mortality. Although surgery is the first-line treatment modality for CD, hypercortisolism persists or recurs in an important subset of patients. Considering the deleterious effects of uncontrolled CD, there is a clear need for effective medical therapy.Objective:In ...
Huang Wenyu - - 2013
The present work describes, for the first time, the use of a new and strong complexing agent, Ethylenediamine-N,N'-disuccinic acid (EDDS) in the homogeneous Fenton process. The effect of H2O2 concentration, Fe(III)-EDDS concentration, pH value and oxygen concentration on the homogeneous Fenton degradation of Bisphenol A (BPA) used as a model ...
Rodríguez-Estival Jaime - - 2013
Lead (Pb) is a highly toxic metal that can induce oxidative stress and affect the immune system by modifying the expression of immunomodulator-related genes. The aim of the present study was to investigate the association between Pb exposure and the transcriptional profiles of some cytokines, as well as the relationship ...
Yoneyama Mitsuru - - 2013
Accelerometry-based gait analysis is widely recognised as a promising tool in healthcare and clinical settings since it is unobtrusive, inexpensive and capable of providing insightful information on human gait characteristics. In order to expand the application of this technology in daily environments, it is desirable to develop reliable gait measures ...
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