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Results 451 - 500 of 3471
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Ben Bacha Abir - - 2013
The best known physiologic function of secreted phospholipase A(2) (sPLA(2)) group IIA (sPLA(2)-IIA) is defense against bacterial infection through hydrolytic degradation of bacterial membrane phospholipids. In fact, sPLA(2)-IIA effectively kills Gram-positive bacteria and to a lesser extent Gram-negative bacteria and is considered a major component of the eye's innate immune ...
Rausch Michael Heinrich - - 2013
Mutual diffusivities for binary mixtures of the ionic liquids (ILs) [EMIM][N(CN)(2)] (1-ethyl-3-methylimidazolium dicyanimide), [EMIM][NTf(2)] (1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide), and [HMIM][NTf(2)] (1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide) with acetone and ethanol were studied in dependence on composition in the temperature range from 283.15 K to 323.15 K applying dynamic light scattering (DLS). The influence of experimental parameters ...
Willis Eloise A - - 2013
Background: Previous studies have shown that of all the tests requested of hospital laboratories, 2540% are thought to be unnecessary. Our hospital laboratory observed that a significant number of requests from the medical admissions unit (MAU) were probably inappropriate. In an attempt to improve requesting behaviour this observation was investigated ...
Dubois Vincent - - 2013
AIM: Potential differences in psychiatric clinical outcomes and hospitalization rates before and after the initiation of long-acting risperidone among recently and long-term diagnosed schizophrenia patients were studied. METHODS: Data from two observational studies (Trial for the Initiation and Maintenance Of REmission in Schizophrenia with risperidone (TIMORES) and electronic Schizophrenia Treatment ...
Larsson P G - - 2013
AIMS/HYPOTHESIS: Enterovirus (e.g. Coxsackie B virus serotypes [CVBs]) infections may be associated with development of type 1 diabetes. Studies conducted in several European countries have, however, shown an inverse correlation between the incidence of type 1 diabetes and the prevalence of enterovirus infections. These findings could in part be explained ...
Götz L-P - - 2013
In the surgical treatment of acetabular fractures via a ventral approach the hip joint is not visible. Hip arthroscopy can be an alternative tool instead of 3-D fluoroscope-based navigation to exclude intra-articular perforation of the screws.
Zhang Yongxian - - 2013
OBJECTIVE: Genetic variants of PPP1R3B, a gene encoding a critical protein involved in hepatic glycogen metabolism were recently reported to be associated with plasma levels of lipids and C-reactive protein (CRP) among populations of mostly European descent. This study aimed to examine whether the PPP1R3B variants are associated with plasma ...
Zheng Dao-Qiong - - 2013
An understanding of the genetic basis underlying the phenotypic variations of yeast strains would guide the breeding of this useful microorganism. Here, comparative functional genomics (CFG) of two bioethanol Saccharomyces cerevisiae strains (YJS329 and ZK2) with different stress tolerances and ethanol fermentation performances were performed. Our analysis indicated that different ...
Bhola Nitin - - 2013
INTRODUCTION: Mandibular fractures are relatively less frequent in children when compared to adults. Pediatric patients present a unique challenge to maxillofacial surgeons in terms of their treatment planning and in their functional needs. We currently describe our experience with lateral compression open cap splint with circummandibular wiring as a treatment ...
Craiem D - - 2013
Aging produces a simultaneous thoracic aorta (TA) enlargement and unfolding. We sought to analyze the impact of hypertension on these geometric changes. Non-contrast computed tomography images were obtained from coronary artery calcium scans, including the entire aortic arch, in 200 normotensive and 200 hypertensive asymptomatic men. An automated algorithm reconstructed ...
Santjohanser Claudia - - 2013
In 1-5 % of patients during childbearing years recurrent miscarriages (RM) occur. There are established risk factors like anatomical, endocrine and hemostatic disorders as well as immunological changes in the maternal immune system. Nevertheless, further elucidation of the pathogenesis remains a matter of debate. In addition, there are no standardized immunological ...
Sgourakis George - - 2013
BACKGROUND: The aim of this study is to evaluate the most cost-effective treatment strategy using preperitoneal mesh for patients with recurrent inguinal hernia. Currently, the issue of cost-effectiveness is entirely unresolved. METHODS: A decision analysis was carried out based on the results of a systematic literature review of articles concerning ...
Nichols S C SC OINDP Consultancy, Rugby, - - 2013
The multi-stage cascade impactor (CI) is widely used to determine aerodynamic particle size distributions (APSDs) of orally inhaled products. Its size-fractionating capability depends primarily on the size of nozzles of each stage. Good Cascade Impactor Practice (GCIP) requires that these critical dimensions are linked to the accuracy of the APSD ...
Neven An - - 2013
Abstract Objective: Persons with multiple sclerosis (PwMS) experience several physical and cognitive problems which can influence their travel behaviour. This study aimed to document the number of activities, the activity type and the transport mode of the related trips that are daily made by PwMS. Their outdoor activity and travel ...
Tritschler P - - 2013
We present the case of a 70-year-old patient presented to our institution for paresthesia of the right hemiface associated with dysarthria in aggravation since 1 year. He was diagnosed with right trigeminal melanoma metastasis. This case is characterized by a thickening of the right trigeminal nerve from his cisternal segment ...
Marwaha Steven - - 2013
PURPOSE: There is weak and inconsistent evidence that mood instability (MI) is associated with depression, post traumatic stress disorder (PTSD) and suicidality although the basis of this is unclear. Our objectives were first to test whether there is an association between depression and PTSD, and MI and secondly whether MI ...
Owens Sarah M - - 2013
One prediction of the classic Ohno model of gene duplication predicts that new genes form from the asymmetric functional divergence of a newly arisen, redundant duplicate locus. In order to understand the mechanisms which give rise to functional divergence of newly formed dispersed duplicates, we assessed the expression and molecular ...
Berney C R - - 2013
PURPOSE: Endoscopic repair of inguinal hernia can decrease the incidence of chronic groin pain. Staple mesh fixation is the surgical technique preferentially used but may also cause residual pain. Although a substantial number of specialists advocate no mesh fixations, concerns are that this could lead to an increase in recurrence ...
McMahon Anne A Department of Ophthalmology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9057, - - 2013
Human meibomian gland secretions (meibum) are the major lipid component of the human preocular tear film. The predominant lipid classes found in meibum include waxes (WE), cholesteryl esters (CE), and varying amounts of cholesterol (Chl). The classical sulfo-phospho-vanillin assay (SPVA), adapted for a microplate reader, was used to quantitate lipids ...
Pentz Mary Ann - - 2013
Considered a set of neuro-cognitive skills, executive cognitive function (ECF) may serve to protect children from initiating substance use, although its role relative to other protective influences that parents and physical activity might provide is not known. As part of a large multiple health risk behavior trial for prevention of ...
Lo Faso Felice - - 2013
INTRODUCTION: The ideal surgical treatment for pulmonary metastasectomy remains controversial. Minimally invasive surgery may offer advantages for quality of life outcomes, with equivalent oncologic long-term results. The purpose of our study was to confirm the validity of the thoracoscopic approach for pulmonary metastasectomy. METHODS: We retrospectively reviewed 164 patients who ...
Sheir Sherin K - - 2013
The effect of previous toxicant exposure (i.e., exposure history) on an organism's response to re-exposure to the toxicant is of considerable interest. The marine mussel Mytilus edulis was collected from reference and polluted sites in southwest England, and groups of mussels from each site were exposed to 20 μg/L CdCl(2) for ...
Weber Benjamin B Department of Pharmaceutics, College of Pharmacy, Center of Pharmacometrics and Systems Pharmacology, University of Florida, Gainesville, FL, - - 2013
Demonstration of equivalence in aerodynamic particle size distribution (APSD) is one key component for establishing bioequivalence of orally inhaled drug products. We previously proposed a modified version of the Chi-square ratio statistic (mCSRS) for APSD equivalence testing and demonstrated that the median of the distribution of the mCSRS (MmCSRS) is ...
Gaudineau A A Department of Maternal and Fetal Medicine, Hautepierre University Hospital, Strasbourg, France. - - 2013
Noonan syndrome is a frequent genetic disorder with autosomal dominant transmission. Classically, it combines postnatal growth restriction with dysmorphic and malformation syndromes that vary widely in expressivity. Lymphatic dysplasia induced during the embryonic stage might interfere with tissue migration. Our hypothesis is that the earlier the edema, the more severe ...
Rizk Elias - - 2013
INTRODUCTION: Suprasellar arachnoid cysts can differ from other arachnoid cysts in several ways, making a separate analysis of these cysts worthwhile. Herein, we present the outcome and perform volumetric analysis of six children with suprasellar arachnoid cysts treated with endoscopic ventriculocystocisternostomy in order to evaluate the long-term outcomes. PATIENTS AND ...
Kauscher Ulrike - - 2013
In this article we describe the introduction of amphiphilic β-cyclodextrins into liposomes to act as artificial receptor units. Using dynamic light scattering, dye encapsulation, and cryogenic transmission electron microscopy it is shown that amphiphilic β-cyclodextrins can be mixed at any proportion with a typical mixture of phospholipids and cholesterol to ...
Ohno Hideaki - - 2013
Histoplasmosis is a fungal infection that, although not endemic in Japan, has seen a rise in the number of Japanese cases since the mid-1980s. Diagnosis of the disease is not straightforward, and the main method of detection, fungal culture (which has biosafety-related issues), is of low sensitivity in general. Alternative ...
Hovnanian Alain - - 2013
Netherton syndrome (NS) is a rare autosomal recessive skin disease with severe skin inflammation and scaling, a specific hair shaft defect and constant allergic manifestations. NS is caused by loss-of-function mutations in SPINK5 (serine protease inhibitor of kazal type 5) encoding LEKTI-1 (lympho-epithelial kazal type related inhibitor type 5) expressed ...
Kang Guozhang - - 2013
The starch-branching enzyme (SBE) catalyzes the formation of branch points by cleaving the α-1,4 linkage in polyglucans and reattaching the chain via an α-1,6 linkage. Three types of SBE isoforms (SBEI, SBEII, and SBEIII) exist in higher plants, with the number of SBE isoforms being species-specific. This study isolated the ...
Kozu Yoshiki - - 2013
A 57-year-old Japanese man presented with massive right pleural effusion, and a huge tumor arising in the pleural cavity was detected by chest computed tomography. A thoracoscopic tumor biopsy revealed that the tumor protruded extensively into the pleural cavity, and its gross appearance was cystic and glossy. Microscopically, the tumor ...
Singh K - - 2013
Therapeutic efficacy of a new 'Indigenous vaccine' prepared from native highly pathogenic 'Indian Bison Type' genotype of Mycobacterium avium subspecies paratuberculosis (MAP) of goat origin has been evaluated with respect to control of clinical Johne's disease in naturally infected Mehsana breed of goat in North Gujarat. Fifty goats from Sheep ...
Lin Han-Yu - - 2013
Telecare medical information systems (TMISs) are increasingly popular technologies for healthcare applications. Using TMISs, physicians and caregivers can monitor the vital signs of patients remotely. Since the database of TMISs stores patients' electronic medical records (EMRs), only authorized users should be granted the access to this information for the privacy ...
Karna Ewa - - 2013
The finding that hydralazine (HYD) affects collagen metabolism led us to investigate the mechanism of its action on collagen biosynthesis, prolidase expression and activity, expression of α(2)β(1) integrin, insulin-like growth factor-I receptor (IGF-IR), focal adhesion kinase (FAK), mitogen-activated protein (MAP) kinases (ERK(1), ERK(2)), and transcription factors hypoxia-inducible factor-1α (HIF-1α) and ...
Yang Baojuan - - 2013
Dasyatis bennettii is a bottom-dweller that inhabits in the coastal waters of the Indian and Pacific Oceans as well as the freshwaters of Southern China. In this study, we determined the complete mitochondrial genome of this species of stingrays. The results showed that the total length of the mitogenome was ...
Peña C - - 2013
The prevalence of multidrug-resistant (MDR) Pseudomonas aeruginosa has increased over the past decade and a significant rise in these isolates in ventilator-associated pneumonia (VAP) has been observed. However, the impact of MDR on VAP outcome has not been analysed in depth. We investigated the risk factors for early and crude ...
Choi Kwang-Dong - - 2013
Anticipation is a phenomenon characterized by decreasing age at onset and increasing severity of symptoms of a disease in successive generations within a pedigree. Anticipation mostly occurs in neurodegenerative diseases with expansion of unstable trinucleotide repeats. However, it has not been previously pointed out in episodic ataxia type 2 (EA2). ...
Filip Agata A - - 2013
Abstract B-cell chronic lymphocytic leukemia (B-CLL) is one of the most common leukemias of the elderly. To date, although many prognostic factors are known, none are universal or easily accessible, thus allowing for the stratification of patients to slow-go and aggressive course groups. Recent studies identified new recurrent mutations in ...
Hammett T C TC Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham, UK. - - 2013
Patients with neuromuscular scoliosis are at increased risk of neurological deficit post-operatively, but are a difficult population on whom to perform neurophysiological monitoring. We look here at a 7-year sample of our practice in the monitoring of neuromuscular patients. A retrospective chart review was performed for 109 patients who underwent ...
Omorou Yacoubou Abdou - - 2013
PURPOSE: The purpose of this study was to investigate the contribution of sport to the association between physical activity (PA) and quality of life (QoL). METHODS: Cross-sectional data were gathered on 4,909 subjects (age 15-69) from the French National Barometer 2005 survey. The International Physical Activity Questionnaire (IPAQ) and the ...
Bowie Christopher R - - 2013
AIM: We examined the efficacy and effectiveness (transfer to functional competence and everyday functioning) of cognitive remediation in early-course (within 5 years of first episode) and long-term (more than 15 years of illness) schizophrenia. METHODS: Treatment lasted 12 weeks and included computerized exercises, strategic monitoring and methods to transfer cognition to behaviour. ...
Mohamed Hasablerasoul E - - 2013
There is suggestive evidence that a low status of ascorbic acid in camels enhances their risk for infectious diseases. This study was carried out to find clues as to the role of diet in affecting ascorbic acid status. In a crossover trial with feeding periods of 3 weeks each, six camels ...
Chang Jie - - 2013
The enzyme from halophilic microorganisms often has unique properties such as organic-solvent-tolerance. In this study, a novel organic-solvent-tolerant α-amylase gene was cloned from the mild halophile Exiguobacterium sp. DAU5. The open reading frame (ORF) of the enzyme consisted of 1,545 bp and encoded 514 amino acids, the primary sequence revealed that ...
Ma Erin S F - - 2013
The known green, five-coordinate, square-pyramidal trans-RuCl(2)(P-N)(PPh(3)) complex reversibly binds water, MeOH and EtOH in the vacant coordination site in the solid state and in CH(2)Cl(2) solution to give pink adducts (P-N = o-diphenylphosphino-N,N'-dimethylaniline). The adducts are well characterized, including X-ray analysis of the aqua complex, trans-RuCl(2)(P-N)(PPh(3))(H(2)O), which crystallizes in two ...
Shi Feng - - 2013
A catalytic asymmetric construction of synthetically and biologically important 2,5-dihydropyrrole scaffolds with concomitant creation of multiple chiral carbon centers including one quaternary stereogenic center in high yields (up to 99%) and excellent enantioselectivities (up to 99% ee) has been established via an organocatalytic 1,3-dipolar cycloaddition using α-arylglycine esters as azomethine ...
Calle-Vallejo Federico - - 2013
The current imbalance in the biogeochemical cycle of nitrogen is as serious as that of carbon. One way to mitigate this problem is through the electrochemical reduction of nitrates under mild conditions, which is an appealing though not fully understood process. Therefore, deeper insight into the electrocatalytic reaction mechanism is ...
Scivoletto Giorgio - - 2013
Abstract Purpose: To calculate the clinical significance of the SCIM III according to distribution-based approaches. Method: Retrospective review of the charts of 255 patients with registration of the total SCIM and of the four subscales. Clinical significance was calculated per several distribution-based approaches. The calculated clinical significance was compared with ...
Simons Daniel J - - 2013
Those who are less skilled tend to overestimate their abilities more than do those who are more skilled-the so-called Dunning-Kruger effect. Less-skilled performers presumably have less of the knowledge needed to make informed guesses about their relative performance. If so, the Dunning-Kruger effect should vanish when participants do have access ...
Shirali Saeid - - 2013
Adenosine is a regulatory molecule with widespread physiological effects in almost every cells and acts as a potent regulator of cell growth. Adenosine has been shown to inhibit cell growth and induce apoptosis in the several cancer cells via caspase activation and Bcl-2/Bax pathway. The present study was designed to ...
Dobbie Melissa J - - 2013
Implementing a statistically valid and practical monitoring design for large-scale stream condition monitoring and assessment programs can be difficult due to factors including the likely existence of a diversity of ecosystem types such as ephemeral streams over the sampling domain; limited resources to undertake detailed monitoring surveys and address knowledge ...
Tumonggor Meryanne K - - 2013
Indonesia, an island nation linking mainland Asia with the Pacific world, hosts a wide range of linguistic, ethnic and genetic diversity. Despite the complexity of this cultural environment, genetic studies in Indonesia remain surprisingly sparse. Here, we report mitochondrial DNA (mtDNA) and associated Y-chromosome diversity for the largest cohort of ...
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