Search Results
Results 351 - 400 of 2583
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Kawachi Yasuhiro - - 2013
Loricrin is a major component of the epidermal cornified cell envelope, and is expressed only in terminally differentiated keratinocytes. This cell differentiation-specific expression pattern suggests specific regulatory mechanisms for activation and suppression of loricrin gene transcription in differentiated keratinocytes. Here, we identified a regulatory element in the proximal promoter region ...
Semenishyn Nikolay - - 2013
Ditopic corroles with lanthanide-binding motifs were prepared and shown to be dual-range emitters, in the visible and near-IR, in ambient conditions.
Mayr Roman - - 2013
Photodynamic Diagnosis (PDD), an adjunct to white light cystoscopy, has been shown to improve detection and thoroughness of resection of bladder cancer by enhancing visualisation of malign lesions during transurethral resection of bladder tumours (TURBT) compared to the sole use of standard white light cystoscopy. The PDD also has been ...
Dors Giniani Carla - - 2013
This study aimed to evaluate the effect of fungicides on rice cultivation regarding the occurrence and the distribution of mycotoxins in fractions of the processed grain, by a validated chromatographic method. A method based on extraction with acetonitrile:water, determination by HPLC-DAD and confirmation by LC-MS was validated before the mycotoxin ...
Densley Konstancja - - 2013
PURPOSE: The aim of this study was to explore the psychometric properties of the 22-item Social Participation Questionnaire (SPQ). METHODS: The SPQ was administered to 789 adult primary care patients with depressive symptoms. As the items were intended to be summed together to provide total score, Rasch analysis (partial credit ...
Huisman Palesa A - - 2013
Abstract Purpose: The aim of this systematic review was to determine the efficacy of thoracic spine manipulation (TSM) in reducing pain and disability in patients diagnosed with non-specific neck pain. Methods: An extensive literature search of PubMed, The Cochrane Library, CINAHL and EMBASE was conducted in February 2012. Randomized controlled ...
Gorlas Aurore - - 2013
Plaque assay is the method traditionally used to isolate and purify lytic viruses, to determine the viral titer and host range. Whereas most bacterioviruses are either temperate or lytic, the majority of known archeoviruses are not lytic (i.e. they are temperate or chronic). In view of the widespread occurrence of ...
Li Qin - - 2013
Abstract Background and objective: To evaluate the effects of ischemia and reperfusion (IR) and ischemic preconditioning (IPC) on the metabolic activities of cytochrome P450 (CYP) isozymes in rats by a five-drug cocktail approach. Methods: Cocktail approach was used to evaluate the influence of IR and IPC on the activities of ...
Stute Annika - - 2013
2-Propenylbis(pentafluorophenyl)phosphane adds Piers' borane [HB(C(6)F(5))(2)] with anti-Markovnikov orientation to yield the intramolecular vicinal frustrated P/B Lewis pair . The FLP adds pyridine, acetonitrile or alkyl isocyanides to form simple boron Lewis acid adducts , all of which were characterized by X-ray diffraction. The FLP reacts with trans-cinnamic aldehyde to give ...
Dornbos Peter - - 2013
River otters are fish-eating wildlife that bioaccumulate high levels of mercury (Hg). Mercury is a proven neurotoxicant to mammalian wildlife, but little is known about the underlying, sub-clinical effects. Here, the overall goal was to increase understanding of Hg's neurological risk to otters. First, Hg values across several brain regions ...
Randriambololona D M A - - 2013
Introduction. Ectopic pregnancy is a serious gynecological disease requiring early diagnosis and treatment. The aim of this study is to analyze the epidemiologic, diagnostic and therapeutic aspects of this disease in a reference hospital in Madagascar. Patients and methods. This prospective and descriptive study included all women diagnosed with and ...
Hanai Nobuhiro - - 2013
BACKGROUND: Recently, the role of chemoradiotherapy (CRT) for preserving organs in the treatment of head and neck cancer has been increasing. However, the indication for post-CRT neck dissection (ND) and its surgical extent is still controversial. The purpose of this study was to discuss the indications for post-CRT ND and ...
Braunschweig Holger - - 2013
Here we report the facile formation of boron-containing cyclic (amino)(imino)carbene complexes by reaction of a chromium borylene complex [(OC)(5)Cr[double bond, length as m-dash]B[double bond, length as m-dash]N(SiMe(3))(2)] with isocyanides.
Brearley Matt B - - 2013
Introduction Responses to physical activity while wearing personal protective equipment in hot laboratory conditions are well documented. However less is known of medical professionals responding to an emergency in hot field conditions in standard attire. Therefore, the purpose of this study was to assess the physiological responses of medical responders ...
Chen Jeng-Rung - - 2013
Brain structures and functions are increasingly recognized to be directly affected by gonadal hormones, which classically determine reproductive functions and sexual phenotypes. In this regard, we found recently that ovariectomy trimmed the dendritic spines of female rat primary somatosensory cortical neurons and estradiol supplement reversed it. Here, we investigated whether ...
Santovito Donato - - 2013
Background: MicroRNAs (miRNAs) are endogenous, non-coding, short, single-stranded RNAs and represent a new class of gene regulators. Recent evidence supports a role for miRNAs in cardiovascular pathophysiology and atherosclerosis development. We have previously demonstrated that miR-145 is widely expressed in human atherosclerotic lesions and its downregulation has been correlated with ...
Stasia Marie J - - 2013
Williams-Beuren syndrome (WBS) is a neurodevelopmental disorder with multi-systemic manifestations, caused by a heterozygous segmental deletion of 1.55-1.83 Mb at chromosomal band 7q11.23. The deletion can include the NCF1 gene that encodes the p47(phox) protein, a component of the leukocyte NADPH oxidase enzyme, which is essential for the defense against microbial ...
Nygaard Ingrid E - - 2013
Many surgeons recommend rest and restricting activities to their patients after surgery. The aim of this review is to summarize the literature regarding types of activities gynecologic surgeons restrict and intra-abdominal pressure during specific activities and to provide an overview of negative effects of sedentary behavior (rest). We searched PubMed ...
Hall L J - - 2013
Natural killer (NK) cells are traditionally considered in the context of tumor surveillance and infection defense but their role in chronic inflammatory disorders such as inflammatory bowel disease is less clear. Here, we investigated the role of NK cells in dextran sodium sulfate (DSS)-induced colitis in mice. Depletion of NK ...
Abou-Rizk Zeina - - 2013
Our interest stems from the dramatic increase in the number of obesity studies, which expose Canadian women to a huge amount of information that links health to weight. Using feminist poststructuralist and postcolonial lenses, this paper investigates young Lebanese-Canadian women's constructions of the body and "health" practices within the context ...
Samassekou Oumar - - 2013
Chronic myeloid leukemia (CML) is a hematologic cancer characterized by the proliferation of myeloid cells and the translocation between chromosomes 9 and 22, [t(9;22)(q34.1;q11.2)]. At the chronic phase (CP), CML cells present longer telomeres than at the other clinical phases, display arm-specific maintenance of individual telomere lengths, and are chromosomally ...
Huang Jennifer H - - 2013
An 11 day-old female infant underwent resection of a mass in the subaortic region secondary to critical aortic stenosis. At 3 months of age, recurrent severe left-ventricular outflow obstruction (LVOT) in the setting of heart failure prompted redo surgery, and the resected mass revealed an intracardiac foregut cyst, which is a rare ...
Choi Hyoungseon - - 2013
Quantification of circulating tumor cells (CTCs) in blood samples is believed to provide valuable evidence of cancer progression, cancer activity status, response to therapy in patients with metastatic cancer, and possible cancer diagnosis. Recently, a number of researchers reported that CTCs tend to lose their epithelial cell adhesion molecule (EpCAM) ...
Menon Manoj P - - 2013
Enzalutamide, formerly known as MDV3100, is an oral second generation androgen receptor (AR) inhibitor that was chosen from a screen of agents and shown in preclinical studies to have greater affinity for the AR than its predecessors without any agonistic effects. The pre-clinical work that led to the interest in ...
Maaskant-Braat Adriana J G - - 2013
Axillary staging in patients with locally recurrent breast cancer is important for obtaining locoregional control and predicting prognosis. The aim of the present study is to determine technical feasibility, validity, aberrant drainage patterns and clinical consequences of performing repeat sentinel node biopsy (SNB) in these patients. We performed a systematic ...
Ráki M - - 2013
Celiac disease (CD) is a chronic small intestinal inflammation precipitated by gluten ingestion. According to case reports, interferon (IFN)-α administration may induce development of overt CD. Plasmacytoid dendritic cells (PDCs) were thought to be the source of IFN-α and promote a T helper type 1 response leading to lesion formation. ...
Peter Kalpak Prafulla - - 2013
Background: Since last few years, association between chronic obstructive pulmonary disease (COPD) and periodontal disease has been promulgated. The present study was aimed at determining the association between these two diseases. Methods: This observational study included 500 individuals consisting of 102 patients (case group) having COPD and 399 individuals as ...
Gidhagen Lars - - 2013
Large-scale exposure assessments that include both between- and within-city differences in air pollution levels are lacking. The objective of this study was to model long-term particle exposure for the whole of Sweden, separating long-range transport from local sources, which were further separated into combustion and road dust. Annual regional, urban ...
Amiel Aliza - - 2013
Abstract Objective: Senescence has been described as a stable cell proliferation arrest resulting from the progression of primary human fibroblasts through a finite number of population doublings in vitro. Accelerated telomere shortening was observed in pregnancies complicated by intrauterine growth restriction (IUGR), in placentas of diabetic mothers, and trisomy 21 ...
Ozer Ayse B - - 2013
PURPOSE: The purpose of our study was to determine the effects of anesthetic technique and ambient temperature on thermoregulation for patients undergoing lower extremity surgery. METHODS: Our study included 90 male patients aged 18-60 years in American Society of Anesthesiologists Physical Status groups I or II who were scheduled for lower ...
Hamzi Khalil - - 2013
The sickle-cell disease is a group of chronic hemolytic diseases which associates three types of injuries: severe anemia, severe infections, and ischemic vaso-occlusive crisis that are secondary to conflicts between small vessels and red blood cells too deformable. Thus, organic various complications may arise. Its prevalence in Europe is estimated ...
Maravic M - - 2013
We described the whole population of patients hospitalized for vertebral fractures in France in 2009. Only 6.4 % of them were operated by vertebroplasty; these patients were younger and healthier than non-operated patients. INTRODUCTION: This study aims to describe the burden of vertebral fractures from the 2009 French Hospital National Database ...
S Don - - 2013
Real-time remote health monitoring systems are experiencing tremendous advancement resulting from improvements in low power, reliable sensors; yet they are still constrained to low-level interpretation. Automatic data analysis continues to be a tedious task due to a lack of efficient, reliable platforms for data analysis. In this paper, we present ...
Higgins M J - - 2013
Disease activity in rheumatoid arthritis (RA) is assessed by a combination of objective and subjective tests, combined to produce a disease activity score in 28 joints (DAS28). There is some evidence that RA disease activity, as assessed by DAS28, can be influenced by vitamin D levels. It is difficult to ...
Keceli Ezgi - - 2013
Three highly fluorescent phosphonates have been prepared in good yields from different arylene bridged 5-iodothiophenes by following an optimized four-step procedure. The compounds have been immobilised on mesoporous zirconia, alumina and titania particles in order to probe their luminescence properties on the surfaces. The organic compounds as well as the ...
Li Ka - - 2013
Background/Aims: The incidence of acute pancreatitis has been increasing recently. This study aims to elucidatethe role of TRAIL signal pathway in the process of acute pancreatitis. Methodology: Pancreatitis models were constructed by cerulein or cerulein plus lipopolysaccharide. Amylase and lipidase were measured in different groups. The mRNA expression of TRAIL, ...
Huang Xiao-Bing - - 2013
In our study, we used the GSE17967 series to identify differentially expressed genes between cirrhosis and hepatocellular carcinoma, aiming to analyse the mechanism of the progression of cirrhosis to hepatocellular carcinoma and identify the sub-pathways closely related to this progression, and find the small molecule drugs to interfere this progression. ...
Krajcovic Jozef - - 2013
This report describes an unusual case of a 2.5-month-old infant's sudden death secondary to giant cell myocarditis and endomyocardial calcification, both unusual entities in pediatric patients. The mother had a history of excessive alcohol consumption during pregnancy and the postnatal period. No infectious etiologies, hypersensivity, or autoimmune disorders were identified. ...
Vajen Beate - - 2013
Suv39h1 mediates heterochromatin formation in pericentric and telomeric regions by trimethylation of lysine 9 of histone 3 (H3K9me3). Yet, its role in the induction of chromosomal instability is poorly understood. We established a leukemia model by retrovirally expressing Myc in wild-type and histone methyltransferase Suv39h1-deficient hematopoietic cells and characterized the ...
Lin Szu-Ting - - 2013
Doxorubicin is an anticancer drug used in a wide range of cancer therapies, yet some side effects have been reported. One of these is cardiotoxicity, including cardiomyopathy and ultimately congestive heart failure. This damage to the heart has been shown to result from doxorubicin-induced reactive oxygen species. However, the cellular ...
Buti D - - 2013
In this work non-invasive reflection infrared spectroscopy was used to discriminate between different Cu-based green pigments (namely, malachite, verdigris, chrysocolla, emerald green and phthalo green). The pigments, chosen because of their historical widespread use in artworks, were investigated as pure powders and in situ on painted models by reflection FTIR ...
Dunn Derek - - 2013
Abstract Among its various catalytic activities, "chymotrypsin-like" activity of proteasome, a large multicatalytic proteinase complex has emerged as the focus of drug discovery efforts in cancer therapy. Herein, we report results from our investigation on a series of peptidomimetic inhibitors.
Gasior Alessandra C - - 2013
INTRODUCTION: No protocol exists for prophylaxis or therapeutic management of peripherally inserted central catheter (PICC) related deep venous thrombosis (DVT) in children. Currently, very few patients are provided prophylaxis for DVT. In this study, we analyzed our current practice of PICC placement to identify the frequency of DVT, analyze risk ...
Poulias Evmenios - - 2013
Background. Previous studies of ridge preservation showed a loss of about 18% or 1.5 mm of crestal ridge width in spite of treatment. The primary aim of this randomized, controlled, blinded clinical trial was to compare a socket graft to the same treatment plus a buccal overlay graft, both with ...
Tsai Hsiu-Hsin - - 2013
PURPOSE: The purpose of this cross-sectional study was to understand the prevalence and risk factors for depressive symptoms among nursing home residents' family caregivers in Taiwan. METHODS: Family caregivers (n = 191) of nursing home residents were recruited by stratified random sampling from 16 nursing homes throughout Taiwan. Data were collected from ...
Trasande Leonardo - - 2013
The impact of air pollution on fetal growth remains controversial, in part, because studies have been limited to sub-regions of the United States with limited variability. No study has examined air pollution impacts on neonatal health care utilization. We performed descriptive, univariate and multivariable analyses on administrative hospital record data ...
Zhu Xuejie - - 2013
Altered expressions of receptor for advanced glycation end-products (RAGE) and its ligand (S100A9) are observed in many cancers and play a key role in inflammation-associated cancer. In our previous study, by two-dimensional gel electrophoresis followed by mass spectrometry, the expression of S100A9 protein was found to increase in squamous cervical ...
Leimbach Andreas - - 2013
Escherichia coli is a paradigm for a versatile bacterial species which comprises harmless commensal as well as different pathogenic variants with the ability to either cause intestinal or extraintestinal diseases in humans and many animal hosts. Because of this broad spectrum of lifestyles and phenotypes, E. coli is a well-suited ...
Madu Anthony Emeka - - 2013
Abstract Feto-maternal transfusion or haemorrhage (FMT) occurs when there is the entry of fetal blood into the maternal circulation in pregnancy or during delivery. It has been stated that very small amount of fetal red cells are normally detectable in maternal circulation in all pregnancies. However, massive FMT is rare ...
Everett Jeremy R - - 2013
The 10th Anniversary of International Drug Discovery Science and Technology (IDDST) Conference was held in Nanjing, China from 8 to 10 November 2012. The conference ran in parallel with the 2nd Annual Symposium of Drug Delivery Systems. Over 400 delegates from both conferences came together for the Opening Ceremony and ...
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