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Results 201 - 250 of 2583
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Verhoye Marleen - - 2013
Abstract Purpose: To evaluate image quality and diagnostic accuracy of High-field post-mortem (PM) magnetic resonance imaging(MRI) on fetuses below 20 weeks of gestation before and after the freeze-thaw process. Materials and Methods: Nine fetuses were scanned with 3 different scanning procedures: "fresh", just after termination of pregnancy(TOP), "non-fresh short scan" ...
Martínez Alvaro - - 2013
Covalent attachment of biorecognizable sugar ligands in several copies at precise positions of cyclomaltooligosaccharide (cyclodextrin, CD) macrocycles has proven to be an extremely flexible strategy to build multivalent conjugates. The commercial availability of the native CDs in three different sizes, their axial symmetry and the possibility of position- and face-selective ...
Wang Yun - - 2013
In our study, metabolomics was used to investigate biochemical changes in the early stages of rats focal cerebral ischemia/reperfusion (I/R) injury. Cerebrospinal fluid (CSF) samples at 0, 0.5, 1, 3, and 6 h of reperfusion (n = 10), based on (1)H NMR spectroscopy and multivariate data analyses, were tested to ...
Farhadi M - - 2013
Background: A subjective feeling of nasal airflow obstruction is a common symptom. An objective method for quantitative measurement of nasal airflow has long been desired. Rhinomanometry and acoustic rhinometry have been developed for anatomical and physiological evaluation of nasal obstruction. This study was designed to determine the usefulness of a ...
Riaz Sara - - 2013
We report the spontaneous fragmentation of gold nanoparticles (AuNPs) induced, in aqueous solution at room temperature, by thiol derivative of ubiquinone, which involves the energetic electron injection from thiol-ubiquinone to the gold nanoparticles.
Rey de Castro Jorge - - 2013
PURPOSE: The purpose of this study is to describe the clinical and polysomnographic differences found in patients diagnosed with obstructive sleep apnea-hypopnea (OSAH), with or without excessive daytime sleepiness (EDS) measured by the Epworth Sleepiness Scale (ESS). METHODS: A physical examination, ESS, and polysomnography were applied to all the participants, ...
Jiang Liangdong - - 2013
Osteosarcoma and Ewing's sarcoma are the two most common primary malignant bone tumors, and findings of prognostic factors are important for clinicians to decide treatment options. High p53 expression has been implicated in tumor development and progression, but studies investigating the prognostic role of p53 overexpression in malignant bone tumors ...
Volpe G - - 2013
The interaction between the receptor Flt3 and its ligand FL leads to crucial signalling during the early stages of the commitment of haematopoietic stem cells. Mutation or over-expression of the flt3 gene, leading to constitutive signalling, enhance the survival and expansion of a variety of leukaemias and is associated with ...
Aytan Hakan - - 2013
PURPOSE: The role of thyroid function in biochemical markers of first trimester screening has not been assessed. The aim of the present study was to investigate if there were any relation between maternal thyroid hormones and free-beta subunit of human chorionic gonadotropin (fβ-hCG) and pregnancy-associated plasma protein A (PAPP-A) levels ...
Kottiappan Madasamy - - 2013
Tea is the most commonly consumed beverage in the world. Tea infusion is prepared by pouring boiling hot water over cured leaves of the Camellia sinensis plant. Such a beverage should be free from toxic chemicals. Studies on the monitoring of pesticide residues in tea of South India had been ...
Inui Yuji - - 2013
Formation of a π-π stacked assembly between a Na(+)-templated G-quartet and octaethylporphyrinatonickel(ii) was observed by spectroscopic methods in methanol/chloroform and the formation dynamics of the assembly was elucidated.
Maydt Daniela - - 2013
Abstract 1. Chalcones are structural analogues of benzalacetophenone (BAP). Several derivatives have been identified in plants and anticarcinogenic and anti-inflammatory properties were attributed to the compounds, probably related to their direct antioxidant activity or stimulatory effects on the expression of endogenous defence enzymes like hemeoxygenase-1 (HO-1). HO-1 expression is triggered ...
Díaz Julián A - - 2013
Unlike the sharp melting behavior of DNA-linked nanoparticle aggregates, the melting of DNA strands from individual gold nanoparticles is broad despite the high surface density of bound DNA. Here, it is demonstrated how sharpened melting can be achieved in colloidal nanoparticle systems using branched DNA-doubler structures hybridized with complementary DNA-doublers ...
Bombard Yvonne - - 2013
Our objective was to explore citizens' informed and reasoned values and expectations of personalized medicine, a timely yet novel genomics policy issue. A qualitative, public deliberation study was undertaken using a citizens' reference panel on health technologies, established to provide input to the health technology assessment process in Ontario, Canada. ...
Abdolahad M - - 2013
Vertically aligned carbon nanotube (VACNT) arrays have been demonstrated as probes for rapid quantifying of cancer cell deformability with high resolution. Through entrapment of various cancer cells on CNT arrays, the deflections of the nanotubes during cell deformation were used to derive the lateral cell shear force using a large ...
Aya-Bonilla Carlos - - 2013
We employed a Hidden-Markov-Model (HMM) algorithm in loss of heterozygosity (LOH) analysis of high-density single nucleotide polymorphism (SNP) array data from Non-Hodgkin's lymphoma (NHL) entities, follicular lymphoma (FL), and diffuse large B-cell lymphoma (DLBCL). This revealed a high frequency of LOH over the chromosomal region 11p11.2, containing the gene encoding ...
Schaerli Yolanda - - 2013
The promise of wide-ranging biotechnology applications inspires synthetic biologists to design novel genetic circuits. However, building such circuits rationally is still not straightforward and often involves painstaking trial-and-error. Mimicking the process of natural selection can help us to bridge the gap between our incomplete understanding of nature's design rules and ...
Babashah Sadegh - - 2013
Aberrant expression and function of microRNAs (miRNAs) in leukemia have added a new layer of complexity to the understanding of development and progression of the disease state. However, their targeting of specific signaling pathways responsible for the maintenance and survival properties of leukemic stem cell (LSC) still remains to be ...
Verspreet Joran - - 2013
The degradation of endogenous wheat grain fructans, oligosaccharides with possible health promoting potential, during wheat whole meal bread making was investigated and several strategies to prevent their degradation were evaluated. Up to 78.4 ± 5.2% of the fructans initially present in wheat whole meal were degraded during bread making by ...
Zhang Ning Jackie - - 2013
Previous studies show that the healthcare industry lags behind many other economic sectors in the adoption of information technology. The purpose of this study is to understand differences in structural characteristics between providers that do and that do not adopt Health Information Technology (HIT) applications. Publicly available secondary data were ...
Bayas Antonios - - 2013
Multiple sclerosis (MS) is the most common neurological disorder leading to permanent disability in early adulthood and premature pension. Prophylactic treatment should be initiated early in the disease process to prevent permanent disability at best. Injectable drugs, i.e., interferon beta preparations and glatiramer acetate, belong to the first-line therapeutics in ...
Zhang Di - - 2013
Background/Aims: It remains a question whether anti-TNF-α treatment is associated with an increase of serious adverse events (SAE) in Crohn's Disease (CD) patients. This study aims to assess the risk of SAE of anti-TNF-α treatment in CD patients. Methodology: Literature search of EMBASE, PubMed, ScienceDirect, Cochrane Library and ClinicalTrials.gov until ...
Somanadhan Brinda - - 2013
A 384-well microtitre plate fluorescence cleavage assay was developed to identify inhibitors of the cysteine protease falcipain-2, an important antimalarial drug target. Bioassay-guided isolation of a MeOH extract from a myxobacterium Chitinophaga sp. Y23 isolated from soil collected in Singapore, led to the identification of a new acyltetrapeptide, falcitidin (1), ...
Ludwig Gerd - - 2013
The synthesis and characterization of cationic ruthenium(ii) complexes of the type [Ru(η(6)-p-cym)Cl{Ph(2)P(CH(2))(n)S(O)(x)Ph-κP,κS}][PF(6)] (n = 1-3; x = 0, 1; p-cym = p-cymene) are presented. Furthermore, their high biological potential even against cisplatin-resistant tumor cell lines and their structure-activity relationships are discussed.
Faria Gil R - - 2013
BACKGROUND: Obesity is a growing public health problem in industrialized countries and is directly and indirectly responsible for almost 10 % of all health expenditures. Bariatric surgery is the best available treatment, however, associated with important economical expenditures. So, cost-effectiveness analysis of the available surgical options is paramount. METHODS: We developed ...
Much D - - 2013
Background/Objective:Evidence is accumulating that the long-chain PUFA (LCPUFA) are associated with offspring growth and body composition. We investigated the relationship between LCPUFAs in red blood cells (RBCs) of pregnant women/breastfeeding mothers and umbilical cord RBCs of their neonates with infant growth and body composition 1 year of age.Subjects/Methods:In an open-label ...
Bertilsson Monica - - 2013
Abstract Purpose: The aim was to explore experiences of capacity to work in persons working while depressed and anxious in order to identify the essence of the phenomenon capacity to work. Method: Four focus groups were conducted with 17 participants employed within the regular job market. Illness experiences ranged from ...
Das Ranendu Sekhar - - 2013
PVP capped platinum nano particles (PNP) of 5 nm diameter were prepared and characterized as homogeneous and of spherical nature. At physiological pH range (6.0-8.0), these PNP catalyze the deoxygenation of phenoxazine group containing resazurin () by hydrazine. The observed rate constants (k(o)), increase linearly with [PNP] at constant [] ...
Hansen C H - - 2013
BACKGROUND: Medical patients are often screened for distress in the clinic using a questionnaire such as the Hospital Anxiety and Depression Scale (HADS) while awaiting their consultation. However, might the context of the clinic artificially inflate the distress score? To address this question we aimed to determine whether those who ...
Conconi A - - 2013
ABSTRACT Central nervous system (CNS) relapse has not been extensively studied in mantle cell lymphoma (MCL). We retrospectively analysed the risk factors and pattern of CNS relapse in consecutive MCL patients. We identified 142 cases of MCL treated from 1980 to 2011. Median age at diagnosis was 68 years; 82% ...
Akinbami Catherine A O - - 2013
In rural Nigeria, food processing is mostly engaged in by women and children. Most of these processes are done using outdated technologies that make use of traditional woodstoves. This article presents the health and environmental implications of the rural female entrepreneurs involved in food processing and proffer means of bettering ...
Costas Benjamín - - 2013
Amino acids (AA) regulate key metabolic pathways, including some immune responses. Therefore, this study aimed to assess whether an increased availability of dietary AA can mitigate the expected increase in plasma cortisol and metabolites levels due to high stocking density and its subsequent immunosuppression. Senegalese sole (Solea senegalensis) were maintained ...
Anderson D P - - 2013
SUMMARY Surveying and declaring disease freedom in wildlife is difficult because information on population size and spatial distribution is often inadequate. We describe and demonstrate a novel spatial model of wildlife disease-surveillance data for predicting the probability of freedom of bovine tuberculosis (caused by Mycobacterium bovis) in New Zealand, in ...
Conroy Thierry - - 2013
In 2010, the FOLFIRINOX regimen (bolus and infusional 5-fluorouracil, leucovorin, irinotecan, and oxaliplatin) emerged as a new option in patients with metastatic pancreatic cancer and a good performance status. However, at that time, some doubts were raised regarding safety issues. Similarly, no data on FOLFIRINOX were published in patients with ...
Withers Kathleen - - 2013
As part of its Medical Technologies Evaluation Programme, the National Institute of Health and Clinical Excellence (NICE) invited the manufacturer, Covidien, to provide clinical and economic evidence for the evaluation of the Pipeline™ embolization device (PED) for the treatment of complex intracranial aneurysms. Cedar; a consortium between Cardiff and Vale ...
Yang Sheng-Tao - - 2013
The protein-nanoparticle (NP) interface is a current frontier of multiple disciplines, full of challenges and opportunities. The unique behaviors of nanomaterials (NMs) bring many exciting applications, and also raise safety concerns. Beyond bioapplications, various NMs could also enter human bodies from the environment. When entering human bodies, NPs interact with ...
Moran V - - 2013
The importance of measuring the quality of mental health care is widely recognized. A number of factors should be considered when constructing mental health quality indicators including the aspects of care to be measured; translation of quality measurement concepts into indicators that can be measured; pilot-testing, analysis and display of ...
Hamanaka Ippei - - 2013
Abstract Objective. This study investigated the shear bond strength of an autopolymerizing repair resin to injection-molded thermoplastic denture base resins. Materials and methods. Four injection-molded thermoplastic resins (two polyamides, a polyethylene terephthalate copolymer and a polycarbonate) were used in this study. The specimens were divided into eight groups according to ...
Kumar Arun - - 2013
Suzuki-Miyaura C-C cross coupling (SMC), an important synthetic strategy for many organic molecules, has several advantages such as mild reaction conditions, high tolerance toward various functional groups and ease in isolation of the product. Palladium(ii) ligated with phosphines (particularly bulky and electron-rich) and N-heterocyclic carbenes (NHCs) has been found to ...
Kaasalainen Touko - - 2013
BACKGROUND: CT optimization has a special importance in children. Smaller body size accentuates the importance of patient positioning affecting both radiation dose and image quality. OBJECTIVE: To determine the effect of vertical positioning on organ dose, image noise and contrast in pediatric chest CT examination. MATERIALS AND METHODS: Chest scans ...
Ben-David Haviv - - 2013
Trifluoroethanol was oxidized with O(2) to trifluoroethyl trifluoracetate (>98% selectivity) using Pt(II)(dppz)Cl(2) as a catalyst in the presence of H(2)SO(4); Pt(II)(phen)Cl(2) was inactive. Kinetic isotope effects suggest the C-H bond activation as the rate determining step and DFT calculations showed different frontier orbitals for Pt(II)(dppz) and Pt(II)(phen)-based catalysts.
Schachat Fred - - 2013
Hodges and his colleagues identified a 12 amino acid fragment of troponin I (TnI-ip) that inhibits Ca(2+)-activated force and reduces the effectiveness Ca(2+) as an activator. To understand the role of troponin C (TnC) in the extended cooperative interactions of thin filament activation, we compared the effect of TnI-ip with ...
Petricevic Mate - - 2013
Excessive bleeding after cardiopulmonary bypass (CPB) is risk factor for adverse outcomes after elective cardiac surgery (ECS). Differentiating between patients who bleed due to surgical issues and those whose excessive chest tube output (CTO) is due to coagulopathy, remains challenging. Bedside suitable tests to identify hemostatic disturbances and predict excessive ...
Abraham S - - 2013
The sterile insect technique (SIT) has been proposed as an area-wide method to control the South American fruit fly, Anastrepha fraterculus (Wiedemann). This technique requires sterilization, a procedure that affects, along with other factors, the ability of males to modulate female sexual receptivity after copulation. Numerous pre-release treatments have been ...
Fullerton G - - 2013
OBJECTIVE: To assess the outcomes of pregnancy following postpartum haemorrhage (PPH) in the first pregnancy. DESIGN: Cohort study. SETTING: Aberdeen Maternity Hospital, Scotland, UK. POPULATION: All women with first deliveries recorded in the Aberdeen Maternity and Neonatal Databank (AMND) between 1986 and 2005. METHODS: All women identified from the AMND ...
Santimano Maria Celisa - - 2013
The extensive production and usage of nanoparticles with ultimate disposal in the environment leads to unintentional exposure of non-target environmentally beneficial bacteria thereby posing a serious threat to the native soil inhabitants. Soil microflora is an important link in the biogeochemical cycling of nutrients, affecting ecosystem functioning and productivity. This ...
Weldon Paul J - - 2013
Nearly 500 alkaloids, representing over 20 structural classes, have been identified from the skin of neotropical poison frogs (Dendrobatidae). These cutaneous compounds, which are derived from arthropod prey of the frogs, generally are believed to deter predators. We tested the red imported fire ant (Solenopsis invicta) for toxicosis following contact ...
Varettas Kerry - - 2013
Allograft musculoskeletal tissue is commonly used in orthopaedic surgical procedures. Cadaveric donors of musculoskeletal tissue supply multiple allografts such as tendons, ligaments and bone. The microbiology laboratory of the South Eastern Area Laboratory Services (SEALS, Australia) has cultured cadaveric allograft musculoskeletal tissue samples for bacterial and fungal isolates since 2006. ...
Rogers C D - - 2013
Wheat bulb fly (WBF, Delia coarctata, Fallén, Diptera: Anthomyiidae) is a pest of commercial importance in wheat, barley and rye, with attacked crops failing to produce full potential yields. Females do not oviposit in association with a host-plant; therefore, prompt location of a suitable host is critical to the survival ...
Goletzke Janina - - 2013
Non-alcoholic fatty liver disease (NAFLD) is closely associated with insulin resistance and obesity. Hence, carbohydrate quality could be of relevance to the risk of NAFLD, but prospective data are lacking. The aim of the present study was to investigate longitudinal associations between carbohydrate quality (including dietary glycaemic index (GI) and ...
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