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Akhtar Z R - - 2013
As a key component of ecological risk assessments, nontarget effects of Bacillus thuringiensis (Bt) rice have been tested under laboratory and field conditions for various organisms. A 2-yr field experiment was conducted to observe the nontarget effects of six transgenic rice lines (expressing the Cry1Ab or fused protein of Cry1Ab ...
Alves Cynthia Maria Soares - - 2013
Objectives To determine reference ranges for measurements of fetal cerebral fissures by 3-dimensional (3D) sonography in the multiplanar mode and to evaluate the reliability and concordance of these measurements. Methods A cross-sectional study was conducted on 393 women with normal pregnancies at 22 weeks to 33 weeks 6 days. The ...
Rand Tatyana A - - 2013
Classical biological control against the alfalfa weevil, Hypera postica (Gyllenhal), a destructive pest of alfalfa (Medicago sativa L.), has resulted in the establishment of nine parasitoid species in the United States. Despite widespread redistribution of a number of species, there remains little postrelease data on their establishment and potential effectiveness ...
Mi Jianing - - 2013
A high-efficient and environmental-friendly method for the preparation of ginsenosides from Radix Ginseng using the method of coupling of ultrasound-assisted extraction with expanded bed adsorption is described. Based on the optimal extraction conditions screened by surface response methodology, ginsenosides were extracted and adsorbed, then eluted by the two-step elution protocol. ...
Ha Pin - - 2013
To obtain descriptive information of behavioral pattern in Chinese school-aged children with cleft lip and palate. A total of 93 cleft lip and palate patients between the age of 6-11 year-old and treated at West China Stomatology Hospital were selected. And another 100 unaffected controls, matched for age and gender, ...
Daane Kent M - - 2013
Habrobracon gelechiae Ashmead (Hymenoptera: Braconidae) was studied as a parasitoid of the obliquebanded leafroller, Choristoneura rosaceana (Harris) (Lepidoptera: Tortricidae) in California pistachio (Pistacia vera L.) orchards. Ovipositional behavior, adult longevity and fecundity, and the effects of temperature on developmental time and survival were determined. Habrobracon gelechiae develops as a gregarious, ...
Wu Lina - - 2013
Arginine is a nonessential amino acid for humans and mice because it can be synthesized from citrulline by argininosuccinate synthetase (ASS) and argininosuccinate lyase. Hepatocellular carcinoma (HCC) is believed to be auxotrophic for arginine through the lack of expression of ASS. However, there are also some ASS-positive HCC cells. Therefore, ...
Han Tian - - 2013
To observe changes in expression of tumor necrosis factor (TNF)-alpha and permeability of blood brain barrier after salidroside pretreatment in rats with injury induced by focal cerebralischemia-reperfusion. Forty-five male SD rats were randomly divided into three groups (n=15): control group, ischemia-reperfusion (IR) model group, and salidroside pretreatment group. Before the ...
Porcel M - - 2013
Green lacewings are generalist predators whose conservation is important for pest control in olive orchards (Olea europaea L.) Sustainable farming practices, as opposed to conventional management techniques, are believed to foster the presence of natural enemies. This study therefore aims to analyze the effect of 1) herbicidal weed cover removal ...
Destounis Stamatia - - 2013
Objectives The aim of this study was to evaluate compression elasticity imaging in combination with standard B-mode imaging for assessment of benign versus malignant breast lesions and correlation with needle biopsy. Methods Institutional Review Board approval was obtained, and patients were prospectively enrolled from 2007 to 2011. A total of ...
Mirza Fadi G - - 2013
BACKGROUND:: The objectives of this study were to develop a murine model of labor and delivery and to use this model to examine whether capsaicin diminishes labor pain and expedites delivery. METHODS:: To develop a murine model of labor pain, the authors identified and compared the incidence of four proposed ...
Eggen Anne Elise - - 2013
To provide a synopsis of the sixth survey of the Tromsø Study, Tromsø 6, objectives and new target areas, study design, follow-up studies, data collection, attendance, and participant characteristics. The Tromsø Study, initiated in 1974, is an epidemiological, prospective study of health conditions and chronic diseases, and a resource for ...
Visentin Silvia - - 2013
We aimed to test the hypothesis that aortic intima thickness is greater in intrauterine growth-restricted (IUGR) twin fetuses compared to normally developing twins, thus defining an increased cardiovascular risk that reflects genetic factors in fetuses sharing the same womb. We conducted a prospective study performed on twins from January 2009 ...
Finger Robert P - - 2013
Multi-attribute utility instruments (MAUIs), which contain a descriptive system, including several health dimensions with associated levels of increasing severity, are used commonly to measure utilities. However, the validity of the descriptive systems rarely is examined using modern psychometric theory. Therefore, we evaluated the psychometric properties of the German version of ...
Umazume Kazuhiko - - 2013
We tested the efficacy of dasatinib, a Food and Drug Administration (FDA)-approved tyrosine kinase inhibitor, to prevent proliferative vitreoretinopathy (PVR). The effect of dasatinib on RPE sheet growth was determined by measuring enlargement of cultured RPE sheets in the presence or absence of dasatinib. Epithelial-mesenchymal transition (EMT) of RPE cells ...
Jekle Andreas - - 2013
Viral conjunctivitis is a highly contagious infection often causing major epidemics. A safe broad-spectrum antiviral agent is needed to treat this unmet medical need. The purpose of this study is to demonstrate that in vitro NVC-422 is a safe, broad-spectrum topical virucidal agent with activity against ophthalmic viral pathogens. The ...
Du Yiqin - - 2013
To investigate the potential of human trabecular meshwork stem cells (TMSCs) for homing to mouse TM tissue and survival in vivo. Human TMSCs and fibroblasts were labeled with fluorescent membrane dye DiO and injected into normal mouse anterior chamber. Stem cell and TM cell markers were identified by immunofluorescent staining ...
Chan Errol W - - 2013
We determined the impact of glaucoma severity and laterality on vision-specific functioning (VF) in an Asian population. The Singapore Malay Eye Study (SiMES) was a population-based cross-sectional study of 3280 Malays aged 40 to 80 years. VF was assessed using the VF-11 questionnaire. Associations between VF-11 score and glaucoma clinical ...
Wall Michael - - 2013
The mean defect (MD) of the visual field is a global statistical index used to monitor overall visual field change over time. Our goal was to investigate the relationship of MD and its variability for two clinically used strategies (Swedish Interactive Threshold Algorithm [SITA] standard size III and full threshold ...
Tanano Ichiro - - 2013
Cilostazol, a selective inhibitor of phosphodiesterase 3, has antiplatelet aggregation and peripheral vasodilation effects. We examined the effects of cilostazol on the retinal microvascular diameter to determine its dependence on the endothelium and/or smooth muscle to reveal the signaling mechanisms involved in this vasomotor activity. Porcine retinal arterioles were isolated, ...
Betz-Stablein Brigid D - - 2013
In order to reduce noise and account for spatial correlation, we applied disease mapping techniques to visual field (VF) data. We compared our calculated rates of progression to other established techniques. Conditional autoregressive (CAR) priors, weighted to account for physiologic correlations, were employed to describe spatial and spatiotemporal correlation over ...
Arciniega Juan C - - 2013
We evaluated quantitatively direct effects of ceramide (Cer) and free cholesterol (FC) on meibomian lipid films (MLF) using a Langmuir trough (LT) and a Brewster angle microscope (BAM). Meibum was obtained from healthy volunteers. A series of mixtures of meibum with Cer or FC (mixed MLF) taken in different ratios ...
Roman Alejandro J - - 2013
To determine the intervisit variability of kinetic visual fields and visual acuity in patients with Leber congenital amaurosis (LCA) caused by mutations in the RPE65 (Retinal Pigment Epithelium-specific protein 65kDa) gene. RPE65-LCA patients (n = 20; ages 11-40 years) were studied on at least two visits separated by fewer than ...
Jose Gilbert G - - 2013
To test the in vivo activity of a peptide derived from the protein transducing domain of the human immunodeficiency virus (HIV) Tat protein, TAT-Cd°, in a murine herpes simplex type 1 (HSV-1) keratitis model. the efficacy of TAT-CD° was assessed in a postinfection treatment model with different concentrations (1 mg/mL, ...
Velez Gisela - - 2013
Proliferative vitreoretinopathy (PVR) is a complication of retinal detachment that can lead to surgical failure and vision loss. Previous studies suggest that a variety of retinal cells, including RPE and Müller glia, may be responsible. Platelet-derived growth factor receptor alpha (PDGFRα) has been strongly implicated in the pathogenesis, and found ...
Hanneken Anne M - - 2013
Visual hallucinations (VHs) occur in macular degeneration patients with poor vision but normal cognitive function. The underlying mechanisms are poorly understood. We report the identification of pharmaceutical agents that enhance VH and use these agents to examine the contribution of retinal neurons to this syndrome. We detail clinical observations on ...
Haeseleer Françoise - - 2013
CaBP4 is a neuronal Ca(2+)-binding protein that is expressed in the retina and in the cochlea, and is essential for normal photoreceptor synaptic function. CaBP4 is phosphorylated by protein kinase C zeta (PKCζ) in the retina at serine 37, which affects its interaction with and modulation of voltage-gated Ca(v)1 Ca(2+) ...
Martin Claude - - 2013
The aim of this meta-analysis was to evaluate renal safety with the active substance of the latest generation of waxy maize-derived hydroxyethyl starch in surgical patients. The authors focused on prospective, randomized, controlled studies that documented clinically relevant variables with regard to renal effects of waxy maize-derived hydroxyethyl starch 130/0.40. ...
Asenbaum U - - 2013
Evaluation and confirmation of fetal pathologies previously suspected or diagnosed with ultrasound. Ultrasound and magnetic resonance imaging (MRI). Technique for prenatal fetal examination. Fetal MRI is an established supplementary technique to prenatal ultrasound. Fetal MRI should only be used as an additional method in prenatal diagnostics and not for routine ...
Gentleman S M SM Neuropathology Unit, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK. - - 2013
Microglia cells have been implicated, to some extent, in the pathogenesis of all of the common neurodegenerative disorders involving protein aggregation such as Alzheimer's disease, Parkinson's disease and Amyotrophic Lateral Sclerosis. However, the precise role they play in the development of the pathologies remains unclear and it seems that they ...
Lu Yao Y Department of Biomedical Engineering, Yale University, New Haven, Connecticut 06520, United - - 2013
Secreted proteins dictate a range of cellular functions in human health and disease. Because of the high degree of cellular heterogeneity and, more importantly, polyfunctionality of individual cells, there is an unmet need to simultaneously measure an array of proteins from single cells and to rapidly assay a large number ...
Stiles Robert J RJ Department of Immunology, College of Medicine, Mayo Clinic, Rochester, Minnesota, - - 2013
Timed matings of mice are often carried out to obtain offspring of a precise age when required for a study. Timed matings involve housing male and female mice together for a limited time period, typically overnight. A limitation of this practice is that many mouse pairs fail to mate during ...
Alworth Leanne C LC College of Veterinary Medicine, University of Georgia, Athens, GA, USA. - - 2013
Physiological and psychological effects of listening to music have been documented in humans. The changes in physiology, cognition and brain chemistry and morphology induced by music have been studied in animal models, providing evidence that music may affect animals similarly to humans. Information about the potential benefits of music to ...
Pucher Philip H - - 2013
BACKGROUND: Management of the acute trauma patient is complex, with potential for error and adverse events. Avoidable injuries and deaths are not well understood. Analysis of error incidence, type, and severity can aid in greater understanding of the root causes and guide future development of error reduction strategies. METHODS: Weekly ...
Mekahli Djalila - - 2013
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of kidney failure. It is a systemic disorder, not only affecting the kidneys, but also associated with cyst formation in other organs such as the liver, spleen, pancreas, and seminal vesicles. Other extra-renal symptoms may consist of intracranial ...
Markar Sheraz R - - 2013
BACKGROUND: The presence of mixed evidence about the value of lymphadenectomy in gastric cancer surgery coupled with the difference in patients' demographics and tumor stage between the West and East have doubted the needs to standardize surgical techniques in Western clinical practice. The purpose of this study was to compare ...
Simon A - - 2013
BACKGROUND: The purpose of this study was to analyze the subjective quality of life in elderly people in nursing homes following the group-living principle. METHODS: The Nottingham Health Profile (NHP) was employed. A comparison with the German representative subsample of elderly living independently age-group over 75 was conducted. Psychometric properties ...
Weiland Timo - - 2013
BACKGROUND: Reliable closure is a prerequisite for conventional and innovative endoscopic procedures, such as NOTES. The purpose of this study is the systematic evaluation of the procedural and clinical success rates in closure of iatrogenic gastrointestinal perforations and acute anastomotic leaks by means of the over-the-scope-clip system (OTSC(®)). DESIGN: PubMed ...
Madersbacher S - - 2013
The pathophysiology of lower urinary tract symptoms (LUTS) is multifactorial. The fact that none of the available drugs impacts on more than one of these pathomechanisms, provides the rationale for combined medical treatment strategies. The combination of α-blocker and a 5-reductase inhibitor is recommended by all major benign prostate hyperplasia ...
Zhao Qun - - 2013
SUMMARYWe report on a case of a 65-year-old Chinese male with locally advanced gastric adenocarcinoma achieving pathological complete response after neoadjuvant chemotherapy with capecitabine and oxaliplatin (XELOX) regimen. He underwent esophagogastroduodenoscopy, which revealed a 6x5cm gastric ulcer. Biopsy of gastric ulcer revealed adenocarcinoma. Further workups with abdominal enhancement computed tomography ...
Nilsson E - - 2013
PURPOSE: To investigate the effects on evoked thalamic neuronal activity of application of notochordal cells and chondrocyte-like cells derived from nucleus pulposus (NP) onto a dorsal root ganglion (DRG) and to compare these effects with a previously reported increased thalamic activity induced by NP. METHODS: Nucleus pulposus was harvested from ...
Lennon Anne Marie - - 2013
Pancreatic cysts are being identified with increasing frequency due to a combination of increased awareness and more frequent use of cross sectional imaging. Cystic neoplasms of the pancreas range from completely benign to frankly malignant. Identifying pre-malignant cysts offers the opportunity to prevent the development of pancreatic cancer. This article ...
Scharnagel R - - 2013
Annually published data show a continual increase in the volume of opioid prescriptions in Germany, thus indicating an intensification of opioid therapy. The majority of opioids are prescribed to treat chronic non-cancer-related pain. On the basis of current guidelines, as well as in terms of the lack of data regarding ...
Pinto Luís Fernando Batista - - 2013
This study aimed to evaluate visual precocity, muscling, conformation, skeletal, and breed scores; live weights at birth, at 205, and at 550 days of age; and, besides, rib eye area and fat thickness between the 12th and 13th ribs obtained by ultrasound. Those traits were evaluated in 1,645 Angus cattle kept ...
Reimer P - - 2013
The manuscript summarizes current approved contrast media and their indications. Contrast agents that are discussed include iodinated contrast agents, magnetic resonance (MR) contrast agents, and ultrasound contrast agents. Allergic and non-allergic renal adverse events are described. The clinical issue of metformin and the administration of contrast agents are updated. Nephrogenic ...
Mildenberger P - - 2013
The term integrating the healthcare enterprise (IHE) has been known for more than 10 years and provides an innovative approach to ensure interoperability based on a synthesis of different standards for defined scenarios. Acceptance and deployment are, however limited in Germany compared with other countries. In this article the basic ...
Kent Shia T - - 2013
Sunlight may be related to cognitive function through vitamin D metabolism or circadian rhythm regulation. The analysis presented here sought to test whether ground and satellite measures of solar radiation are associated with cognitive decline. The study used a 15-year residential history merged with satellite and ground monitor data to ...
Müller S - - 2013
The question which party bears the burden of proof has significant influence on the result of a medical liability process. The party that bears the burden of proof and cannot provide the proof loses the lawsuit. Particularly important in this context is an omitted medical examination. In the case of ...
Seemann M - - 2013
This article reports on a patient who needed intensive care treatment because of multiple trauma. The patient had no preexisting liver disease but developed secondary sclerosing cholangitis and finally died. The etiology, diagnosis and therapeutic options of this clinical picture are discussed and a review of the literature is presented.
Kaibori Masaki - - 2013
BACKGROUND: The present study aimed to clarify the clinicopathologic features of long-term disease-fee survival after resection of hepatocellular carcinoma (HCC). METHODS: This retrospective study identified 940 patients who underwent curative resection of HCC between 1991 and 2000 at five university hospitals. Seventy-four patients with 10 years of recurrence-free survival were identified ...
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