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Results 701 - 750 of 2582
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Yang Frances M - - 2013
ABSTRACT: BACKGROUND: Delirium (acute confusion), is a common, morbid, and costly complication of acute illness in older adults. Yet, researchers and clinicians lack short, efficient, and sensitive case identification tools for delirium. Though the Confusion Assessment Method (CAM) is the most widely used algorithm for delirium, the existing assessments that ...
Tamatani Tetsuya - - 2013
Oral cancer cells have a significantly augmented nuclear factor-κB (NF-κB) activity and the inhibition of this activity suppresses tumor growth. Bortezomib is a proteasome inhibitor and a drug used for molecular-targeted therapy (targets NF-κB). In this study, we investigated whether bortezomib would be effective as an inhibitor of proliferation and ...
Jasper Edward - - 2013
Disaster preparedness training is a critical component of medical student education. Despite recent natural and man-made disasters, there is no national consensus on a disaster preparedness curriculum. The authors designed a survey to assess prior disaster preparedness training among incoming interns at an academic teaching hospital. In 2010, the authors ...
Koyama Shinsuke - - 2013
In many cortical areas, neural spike trains do not follow a Poisson process. In this study, we investigate a possible benefit of non-Poisson spiking for information transmission by studying the minimal rate fluctuation that can be detected by a Bayesian estimator. The idea is that an inhomogeneous Poisson process may ...
Pina-Hernandez Carlos - - 2013
A novel and robust route for high-throughput, high-performance nanophotonics-based direct imprint of high refractive index and low visible wavelength absorption materials is presented. Sub-10 nm TiO(2) nanostructures are fabricated by low-pressure UV-imprinting of an organic-inorganic resist material. Post-imprint thermal annealing allows optical property tuning over a wide range of values. For ...
Petrosillo Nicola - - 2013
ABSTRACT: Cigarette smoking is one of the most important causes of morbidity and mortality in the general population, and is a well-recognized risk factor for a variety of serious clinical conditions, including cardiovascular diseases, pulmonary diseases and cancers. Smoking-related morbidity and mortality are of particular concern in patients with HIV ...
Liu Ye-Hua - - 2013
We propose a mechanism to pin skyrmions in chiral magnetic thin films by introducing local maxima of magnetic exchange strength as pinning centers. The local maxima can be realized by engineering the local density of itinerant electrons. The stationary properties and the dynamical pinning and depinning processes of an isolated ...
Mazin Pavel - - 2013
While splicing differences between tissues, sexes and species are well documented, little is known about the extent and the nature of splicing changes that take place during human or mammalian development and aging. Here, using high-throughput transcriptome sequencing, we have characterized splicing changes that take place during whole human lifespan ...
Maekawa Fumihiko - - 2013
Sexual differentiation leads to structural and behavioural differences between males and females. Here we investigate the intrinsic sex identity of the brain by constructing chicken chimeras in which the brain primordium is switched between male and female identities before gonadal development. We find that the female chimeras with male brains ...
Kleinke Andrew S - - 2013
The first continuous hydrogenation that requires neither H(2) nor metal catalysis generates diimide by a novel reagent combination. The simple flow reactor employed minimizes residence time by enabling safe operation at elevated temperature.
Simonsen Hanne Gram - - 2013
In this article, we present a study of imageability ratings for a set of 1599 Norwegian words (896 nouns, 483 verbs and 220 adjectives) from a web-based survey. To a large extent, the results are in accordance with previous studies of other languages: high imageability scores in general, higher imageability ...
Li Feng - - 2013
Density functional theory calculations and first-principles molecular dynamics (MD) simulations have been performed to examine the strain effect on the colossal oxygen ionic conductivity in selected sandwich structures of zirconia electrolytes. For the KTaO(3)/YSZ/KTaO(3) sandwich structure with 9.7% lattice mismatch, transition state calculations indicate that the strain effect changes the ...
Bu Hang-Beom - - 2013
Water soluble nanoparticles (NPs) with a high emission property were synthesized via hydrothermal routes. In this report, we chose thiol ligand N-acetyl-l-cysteine as the ideal stabilizer and have successfully employed it to synthesize readily size-controllable CdTe NPs in a reaction of only one step. Hydrothermal synthesis of CdTe NPs has ...
Michalak Krzysztof W - - 2013
OBJECTIVES: Neoaortic root changes in children with transposition of the great arteries (TGA) are reportedly risk factors for the development of neoaortic regurgitation (NeoAR). The aims of this study were to assess the neoaortic root diameter and relative proportion in children with TGA after surgical correction and to identify possible ...
Liu Yi-Tao - - 2013
We report a universal strategy for the hierarchical assembly of nanoparticles on various 2D materials, resulting in functional 0/2D nanohybrids holding great promise in catalysis, energy storage, and chemical and biological sensing.
Wang Yicheng - - 2013
Composition-tunable semiconductor alloy nanowires are emerging as an important class of materials for the realization of high-performance laterally-arranged multiple bandgap (LAMB) solar cells. Here we report the first growth of GaZnSeAs quaternary alloy nanowires with composed elements between two different groups using a temperature/space-selective CVD route. Under laser excitation, these ...
Palagin Dennis - - 2013
Density-functional theory based global geometry optimization is used to scrutinize the possibility of using endohedrally-doped hydrogenated Si clusters as building blocks for constructing highly magnetic materials. In contrast to the known clathrate-type facet-sharing, the clusters exhibit a predisposition to aggregation through double Si-Si bridge bonds. For the prototypical CrSi(20)H(20) cluster ...
Bica Katharina - - 2013
The molar polarisability and molar volume for 71 ionic liquids were extracted from 157 measurements of their refractive index and density, which were then further deconstructed into atomic contributions by means of a Designed Regression analysis. Using this approach, the density and refractive index for any chosen ionic liquid with ...
Galzerano Antonio - - 2013
Medullary breast carcinoma (MBC) is a rare epithelial malignancy of the breast accounting for about 1-7% of all breast carcinomas. It is characterized by well-defined borders, a syncytial/solid pattern of growth of high grade atypical cells showing no glandular differentiation and a massive diffuse lympho-plasmacytic peritumoral infiltrate. Despite the high-grade ...
Alexander Bobby - - 2013
Hypothesis. Although several conventional therapeutic options for advanced renal cell carcinoma (RCC) are currently available, the unsatisfactory outcomes demand establishing more effective interventions. D-fraction (PDF), a bioactive proteoglucan of Maitake mushroom, demonstrates anticancer and immunomodulatory activities, which are also shown to be potentiated by vitamin C (VC). We thus hypothesized ...
Zwanenburg Alex - - 2013
Background:The understanding of hypoxemia-induced changes in baroreflex function is limited and may be studied in a fetal sheep experiment before, during, and after standardized hypoxic conditions.Methods:Preterm fetal lambs were instrumented at 102 days gestation (term: 146 days). At 106 days intra-uterine hypoxic-ischemia was induced by 25-min of umbilical cord occlusion ...
Torricelli Michela - - 2013
Abstract Objective: To evaluate whether maternal weight and BMI and their increase throughout pregnancy are associated with the response to labor induction in postdate pregnancies. Methods: A total of 376 nulliparous women carrying singleton postdate pregnancies with unfavorable cervix were enrolled. We considered as primary outcome vaginal delivery within 24 ...
Pilgrim Thomas - - 2013
Aims: Coronary artery disease (CAD) and atrial fibrillation (AF) are major determinants of morbidity and mortality. A combined treatment with antiplatelet agents and vitamin K antagonists limits the risk of stent thrombosis and stroke while increasing the rate of bleeding. The objective of this study was to investigate the impact ...
Godefroit Pascal - - 2013
Feathered theropods were diverse in the Early Cretaceous Jehol Group of western Liaoning Province, China. Recently, anatomically distinct feathered taxa have been discovered in the older Middle-Late Jurassic Tiaojishan Formation in the same region. Phylogenetic hypotheses including these specimens have challenged the pivotal position of Archaeopteryx in bird phylogeny. Here ...
Assmann Marcus-Alexander - - 2013
Intracellular cargos that are transported by groups of molecular motors often display bidirectional movement. This can be seen experimentally by tracking the trajectories of individual cargos in vivo. Typically, the cargo trajectories display many turning events that result from the stochastic nature of the involved motor processes. In this paper, ...
Hakki Amer - - 2013
The photocatalytic conversion of various nitroaromatic compounds in alcohols employing four different types of TiO(2) (Sachtleben Hombikat UV100 as anatase, Crystal Global R34 as rutile, Evonik-Degussa Aeroxide P25 as an anatase-rutile mixture, and home-made mesoporous anatase) has been studied. The effect of platinization of these different types of TiO(2) on ...
Granelli Pietro - - 2013
Background: The endourological technique is a safe and effective approach in the treatment of large stones in the pediatric population with congenital malformations.
Introduction: The VACTERL association is a group of congenital malformations that include vertebral defects, anal atresia, cardiac defects, tracheoesophageal fistula with atresia, renal defects, and radial upper limb ...
Vachhani Dipak D - - 2013
Coupling the strangers: A copper-catalyzed three-component heteroarene-amine-aldehyde/ketone coupling affords a novel approach to the hitherto difficult direct secondary/tertiary CH alkylation of azoles. This simple method allows the facile installation of diversely substituted, branched and nitrogen-containing alkyl or alkaloid side chains on the azole moiety using readily available starting materials.
Nori-Shargh Davood - - 2013
The structural properties of ethene (1) and tetrahydridodimetallenes M2H4, [M= Si (2), Ge (3), Sn (4)] have been examined by means of CCSD(T)/Def2-TZVPP, MP4(SDTQ)/Def2-TZVPP, B3LYP/Def2-TZVPP levels of theory and natural bond orbital analysis (NBO) interpretations. The results obtained showed the expected planar ground state structure for compound 1 (D2h symmetry) ...
Campbell Peter T - - 2013
PURPOSELittle is known about the association of recreational physical activity or leisure time spent sitting with survival after colorectal cancer diagnosis. This study examined the associations of prediagnosis and postdiagnosis recreational physical activity and leisure time spent sitting with mortality among patients with colorectal cancer. PATIENTS AND METHODSFrom a cohort ...
Hu Y - - 2013
Numerical simulation of the photocurrent density is performed for a two-junction nanowire (NW)-on-silicon solar cell under AM1.5G illumination. The photocurrent density is determined for NW diameters from 100-250 nm, period (spacing) from 250-1000 nm, and length of 5 μm. The dependence of photocurrent density on NW bandgap is also determined. For each NW ...
Haas Jan - - 2013
Dilated cardiomyopathies (DCM) show remarkable variability in their age of onset, phenotypic presentation, and clinical course. Hence, disease mechanisms must exist that modify the occurrence and progression of DCM, either by genetic or epigenetic factors that may interact with environmental stimuli. In the present study, we examined genome-wide cardiac DNA ...
Chinga-Carrasco G - - 2013
Wood pulp fibres are an important component of environmentally sound and renewable fibre-reinforced composite materials. The high aspect ratio of pulp fibres is an essential property with respect to the mechanical properties a given composite material can achieve. The length of pulp fibres is affected by composite processing operations. This ...
Yakushiji Tadayuki - - 2013
Aims: We report the intravascular ultrasound (IVUS) analysis of plaque distribution in left anterior descending (LAD) artery/first diagonal (D1) and distal left main coronary artery (LMCA) bifurcation lesion location. Methods and results: We reviewed 58 angiograms of LAD/D1 bifurcation lesions with pre-intervention IVUS of both the LAD and D1 and ...
Staniczenko Phillip P A - - 2013
Ecologists are fascinated by the prevalence of nestedness in biogeographic and community data, where it is thought to promote biodiversity in mutualistic systems. Traditionally, nestedness has been treated in a binary sense: species and their interactions are either present or absent, neglecting information on abundances and interaction frequencies. Extending nestedness ...
Bada Jeffrey L - - 2013
1953 was a banner year for biological chemistry: The double helix structure of DNA was published by Watson and Crick, Sanger's group announced the first amino acid sequence of a protein (insulin) and the synthesis of key biomolecules using simulated primordial Earth conditions has demonstrated by Miller. Miller's studies in ...
Parma Paolo - - 2013
Introduction: We present our technique of laparoscopic nephrectomy with intact specimen extraction for patient with autosomal dominant polycystic kidney disease (ADPKD).
Materials and Methods: A 5-port retroperitoneal laparoscopic approach was used to dissect the involved kidney, which was then removed intact through a Gibson modified incision.
Results: The operative time was 110 ...
Wang Jie - - 2013
AIMS: The anti-cancer anthracycline doxorubicin (DOX) increases the risk of cardiac damage, indicating a need to protect the heart and still allow the benefits of drug treatment. Fibroblast growth factor-2 (FGF-2) is cardioprotective against ischemia-reperfusion injury. Our aim is to investigate: (1) the ability of FGF-2 to protect against DOX-induced ...
Fuchs Ido - - 2013
It is shown that in general, when sub-micron hybrid particles of polymer@silica, are subjected to thermal treatment, phase-separated hydrophobicity emerges at particles surface; and that the triggering of hydrophobicity results in particles which show amphiphilic behavior, arranging themselves at water interfaces and stabilizing W/O and O/W emulsions. Many polymer@silica particles ...
Ciau Nancy - - 2013
Schwannomas arising in the parotid gland or peri-parotid region is frequently misdiagnosed as pleomorphic adenoma on cytologic preparations. The epithelioid variant of schwannoma is particularly susceptible to misdiagnosis because this neoplasm typically has epithelioid and spindled cells, which are associated with fibrillar stroma and mimic the epithelial, myoepithelial, and stromal ...
Yadav J S - - 2013
A novel method has been devised for anti-1,3-aminoalcohols through reductive elimination of iodomethyltetrahydropyrans which are in turn derived from a Prins/Ritter reaction sequence. The synthetic versatility of this method has been explored in the total synthesis of piperidine alkaloids and β-amino acids.
Guevara-Aguirre Jaime - - 2013
Context:The maximum dose of IGF-I recommended for treatment of GH insensitivity is commonly used.Objective:The aim was to test the hypothesis that a lower dose is as effective as a high dose of IGF-I in growth promotion and has fewer deleterious effects.Design and Setting:Subjects were treated for 3 years with regular ...
Vierck Esther - - 2013
Objective:Binocular rivalry refers to a situation where contradictory information is presented simultaneously to the same location of each eye. This leads to the alternation of images every few seconds. The rate of alternation between images has been shown to be slower in euthymic participants with bipolar disorder than in healthy ...
Zhou Jigang - - 2013
Visualization of the state of charge (SOC) in an LiMn(0.75)Fe(0.25)PO(4) nanorods-graphene hybrid nanostructure (LMFP-C) is realized by chemical mapping of the Fe valance state using scanning transmission X-ray microscopy (STXM). The LMFP-graphene interaction strength variation studied by C K-edge STXM has been correlated to SOC variation, i.e. a stronger interaction ...
Sun Hanjun - - 2013
As a rising star in the family of fluorescent material, graphene quantum dots (GQDs) have attracted great attention because of their excellent properties such as high photostability against photobleaching and blinking, biocompatibility and low toxicity. Herein, blue luminescent GQDs were prepared by photo-reducing GQDs with isopropanol. After photochemical reduction, the ...
Jones Charles H - - 2013
Well-defined cationic polylactides (CPLAs) with tertiary amine groups were synthesized by thiol-ene click functionalization of an allyl-functionalized polylactide to yield polymers with tunable charge densities. CPLAs have not previously been utilized in the context of DNA delivery. Thus, plasmid DNA (pDNA) encoding luciferase was delivered to two physiological distinct cell ...
Jansen Felix - - 2013
AIMS: Diabetes is a major risk factor for cardiovascular diseases. Circulating endothelial microparticles (EMP) are increased in diabetic patients, but their potential contribution in atherogenesis is unclear. We sought to determine the role of EMP derived under high glucose conditions in the development of atherosclerosis. METHODS AND RESULTS: EMP were ...
Arnold Heather M - - 2013
BACKGROUND:β-Lactam antibiotics demonstrate time-dependent killing. Prolonged infusion of these agents is commonly performed to optimize the time the unbound concentration of an antibiotic remains greater than the minimum inhibitory concentration and decrease costs, despite limited evidence suggesting improved clinical RESULTS: To determine whether prolonged infusion of β-Lactam antibiotics improves outcomes ...
Menez Steven - - 2013
Objective. To determine and compare the perspectives of the general public and health care providers (HCPs) on obesity and its treatment in rural West Virginia (WV) and Baltimore, MD. Method. Surveys were completed in both locations by the general public (WV: n = 200; Baltimore: n = 171) and HCPs ...
Dai Hua - - 2013
We describe an automation-friendly chemiluminescent immunoassay method for sensitive and rapid determination of chicken interferon-γ at the sub-picogram per millilitre level based on the monoclonal antibody immobilized paramagnetic microspheres and flow-through system.
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