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Results 651 - 700 of 2583
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Marshak Michael P - - 2013
The reaction of Na(OSi(t)Bu(2)Me) with CrCl(3) yields solid [Cr(OSi(t)Bu(2)Me)(3)](n) (1), which can be crystallized in the presence of excess Na(OSi(t)Bu(2)Me) to yield [Na(THF)][Cr(OSi(t)Bu(2)Me)(4)] (2). This complex is oxidized to yield Cr(OSi(t)Bu(2)Me)(4) (3), a crystalline chromium(IV) siloxide complex that is air- and moisture-stable. Electronic spectroscopic analysis of the absorption spectrum of ...
San Sebastián Eider - - 2013
The integrin leukocyte function associated antigen 1 (LFA-1) binds the intercellular adhesion molecule 1 (ICAM-1) by its α(L)-chain inserted domain (I-domain). This interaction plays a key role in cancer and other diseases. We report the structure-based design, small-scale synthesis, and biological activity evaluation of a novel family of LFA-1 antagonists. ...
Muñoz Caro Guillermo M - - 2013
A compendium of different solid carbonaceous materials detected in space is presented, focussing on the search for organic matter of prebiotic interest. This journey takes us from the carbon grains likely formed in the atmospheres of evolved stars to organic grain mantles made from ice processing thought to be present ...
von Cube Felix - - 2013
Metamaterials are artificial media which can provide optical properties not available from natural materials. These properties often result from the resonant excitation of plasmonic modes in the metallic building blocks ("metaatoms") of the metamaterial. Electromagnetic interactions between the metaatoms significantly modify the resonances of the individual metaatoms and influence the ...
Yuan Jiajia - - 2013
Chemotaxis (detecting and following chemical gradients) plays a crucial role in the function of many biological systems. In particular, gradient following by neuronal growth cones is important for the correct wiring of the nervous system. There is increasing interest in the constraints that determine how small chemotacting devices respond to ...
Yamamoto Shigeki - - 2013
Low-frequency vibrational bands observed in Raman and THz spectra in the region of 50-150 cm(-1) of crystalline powder poly-(R)-3-hydroxybutyrate (PHB) were assigned based on comparisons of the Raman and THz spectra, polarization directions of THz absorption spectra, and their congruities to quantum-mechanically (QM) calculated spectra. This combination, Raman and THz ...
Sangiambut S - - 2013
The addition of enzyme biofunctionality to self-assembling peptide nanofibers is challenging since such additions can inhibit functionality or self-assembly. We introduce a method for peptide nanofiber enzyme functionalization, demonstrated by the attachment of a polymerization synthase to peptide nanofibers. The enzyme generates a biocompatible, biodegradable biopolyester coat on the fibers ...
Esvelt Kevin M - - 2013
Genome-modification technologies enable the rational engineering and perturbation of biological systems. Historically, these methods have been limited to gene insertions or mutations at random or at a few pre-defined locations across the genome. The handful of methods capable of targeted gene editing suffered from low efficiencies, significant labor costs, or ...
Gao Yi - - 2013
In order to gain molecular level understanding of drug dissolution into aqueous media, we report the first molecular dynamics (MD) simulation of a drug crystal dissolving. The simulation was performed for acetaminophen crystal Form I dissolving in 0.15 M aqueous NaCl solution at 37 °C. The 10 ns simulation revealed ...
Abiko Kaoru - - 2013
PURPOSE: Ovarian cancer often progresses by disseminating to the peritoneal cavity, but how the tumor cells evade host immunity during this process is poorly understood. Programmed cell death 1 ligand 1 (PD-L1) is known to suppress immune system and to be expressed on cancer cells. The purpose of this study ...
Yang Chao - - 2013
An autofluorescent whole-cell biocatalyst capable of simultaneously degrading organophosphates (OPs) and γ-hexachlorocyclohexane (γ-HCH) was constructed by display of organophosphorus hydrolase (OPH) and green fluorescent protein (GFP) fusion on the cell surface of a γ-HCH-degrading Sphingobium japonicum UT26 using the truncated ice nucleation protein (INPNC) as an anchoring motif. The surface ...
Kimberley Teresa Jacobson - - 2013
Purpose: The ability of low-frequency repetitive transcranial magnetic stimulation (rTMS) to enhance intracortical inhibition has motivated its use as a potential therapeutic intervention in focal hand dystonia (FHD). In this preliminary investigation, we assessed the physiologic and behavioral effects of multiple sessions of rTMS in FHD. Methods: 12 patients with ...
Acosta Juan Camilo - - 2013
A novel dual tip nanomanipulation atomic force microscope (AFM) platform operating in ambient conditions is presented. The system is equipped with a high frequency quartz piezoelectric self-sensing scanning probe for fast imaging and a passive cantilever for manipulation. The system is validated by imaging and selective pushing/pulling of gold colloid ...
Hawley Pippa - - 2013
Background:This case report describes a patient who developed severe bradycardia due to transdermal fentanyl. There have been no prior case reports of this occurring in palliative care, but the frequency of association of fentanyl with bradycardia in the anesthesia setting suggests it may be more common than realized. Palliative care ...
Feng Xiaoyi - - 2013
We report in this work real time characterization of enzyme-coenzyme binding by using surface plasmon resonance (SPR) and dual polarization interferometry (DPI) analyses. Results showed that diaphorase (DP) and lactate dehydrogenases (LDH) had distinct binding selectivity and preference over reduced and oxidized states of coenzyme NAD(H). Based on that, DP ...
Park Kwangsuk - - 2013
The charge transport properties in the TiO2 nanoparticle networks with the different TiO2 nanoparticle sizes were investigated by means of electrochemical impedance spectroscopy (EIS) with consideration of morphological aspects of mesoporous TiO2 network including particle size (dp), coordination number (Nn), neck diameter (dn) and effective surface area (Se). The morphological ...
Kosov Daniel S - - 2013
We present a derivation of the Markovian master equation for an out-of-equilibrium quantum dot connected to two superconducting reservoirs, which are described by the Bogoliubov-de Gennes Hamiltonians and have the chemical potentials, the temperatures, and the complex order parameters as the relevant quantities. We consider a specific example in which ...
Hung Yu-Wen - - 2013
ABSTRACT: BACKGROUND: Epilepsy is a common brain disorder characterized by a chronic predisposition to generate spontaneous seizures. The mechanisms for epilepsy formation remain unknown. A growing body of evidence suggests the involvement of inflammatory processes in epileptogenesis. In the present study, we investigated the involvement of monocyte chemoattractant protein-1 (MCP-1) ...
Han Pan - - 2013
ABSTRACT: BACKGROUND: Ultrasonography is a convenient technique to investigate muscle properties and has been widely used to look into muscle functions since it is non-invasive and real-time. Muscle thickness, a quantification which can effectively reflect the muscle activities during muscle contraction, is an important measure for musculoskeletal studies using ultrasonography. ...
Mai Zhensheng - - 2013
Anion exchange membranes prepared from quaternized poly(tetramethyl diphenyl ether sulfone) (QAPES) were first investigated in the context of vanadium flow battery (VFB) applications. The membranes showed an impressive suppression effect on vanadium ions. The recorded vanadium permeability was 0.02×10(-7) -0.09×10(-7)  cm(2)  min(-1) , which was two orders of magnitude lower ...
Berthoumieux Sara - - 2013
Gene expression is controlled by the joint effect of (i) the global physiological state of the cell, in particular the activity of the gene expression machinery, and (ii) DNA-binding transcription factors and other specific regulators. We present a model-based approach to distinguish between these two effects using time-resolved measurements of ...
Liu Kaihui - - 2013
Van der Waals-coupled materials, ranging from multilayers of graphene and MoS(2) to superlattices of nanoparticles, exhibit rich emerging behaviour owing to quantum coupling between individual nanoscale constituents. Double-walled carbon nanotubes provide a model system for studying such quantum coupling mediated by van der Waals interactions, because each constituent single-walled nanotube ...
Wang Dong Hwan - - 2013
Layer by layer: Electron-transport layers (ETLs) of transferable graphene oxide (GO) inserted by using a stamping nanotechnology result in bulk-heterojunction (BHJ) solar cells with enhanced power conversion efficiency because of enhanced electron-charge transport and reduced electronic charge barrier with low series resistance. The GO ETL also increases the stability of ...
Zheng Jianghua - - 2013
PURPOSE: Prostate cancer (PCa) is the second leading cause of cancer deaths among men in Western counties, which has been also occurred in Chinese male with markedly increasing incidence in recent years. Although the mechanism underlying its progression still remains unclear, epigenetic modifications are important ethological parameters. Exrimental Design: The ...
Dash Chandrakanta - - 2013
Cationic copper(I) dicarbonyl complexes supported by N-heterocyclic carbene ligands, SIPr and IPr*, have been synthesized. [(SIPr)Cu(CO)(2)][SbF(6)] and [(IPr*)Cu(CO)(2)][SbF(6)] have a trigonal planar, three-coordinate copper atom with an average Cu-CO distance of 1.915 Å and display C-O stretching frequencies higher than that of the free CO (2143 cm(-1)). The high CO ...
Calogero Rachel M - - 2013
Integrating system-justification and objectification theories, the research reported here broadens the scope of prior work on women's self-objectification to examine its system-justifying function. I investigated the relation of trait and state self-objectification to support for the gender status quo and engagement in gender-based social activism among U.S. college women. Study ...
Fellmer P T - - 2013
Introduction: Vascular graft infection in peripheral bypass surgery represents a highly significant risk with regard to limb loss and morbidity. In the absence of autologous superficial veins, finding a suitable replacement material can be difficult. Silver-coated polyester grafts, homografts, or use of deep veins can pose additional risks. Use of ...
Iesari Samuele - - 2013
Context:Obesity is characterized by decreased insulin-stimulated glucose uptake in muscle and shift from glucose to lipid oxidation, the so-called metabolic inflexibility. Biliopancreatic diversion (BPD), a mainly malabsorptive bariatric operation, determines a prompt improvement of insulin resistance, but the mechanisms are still unclear.Objective:We aimed to estimate the response of glucose transporter ...
Rubino Stephen J - - 2013
Muramyl peptides (MPs) represent the building blocks of bacterial peptidoglycan, a critical component of bacterial cell walls. MPs are well characterized for their immunomodulatory properties, and numerous studies have delineated the role of MPs or synthetic MP analogs in host defense, adjuvanticity and inflammation. More recently, Nod1 and Nod2 have ...
Löhr C V - - 2013
Of 1146 caprine necropsy or biopsy specimens submitted from 1987 through 2011 to the Veterinary Diagnostic Laboratory at Oregon State University, 100 goats (8.7%) had 102 tumors. Detailed records were available for 89 cases. Fifty-five goats were female, 17 were castrated males, and 12 were intact males. Breeds included 21 ...
Cao Feng - - 2013
In our previous studies, ethylene glycol-linked amino acid diester prodrugs of Oleanolic Acid (OA), a Biopharmaceutics Classification System (BCS) Class Ⅳ drug, designed to target peptide transporter 1 (PepT1) have been synthesized and evaluated. Unlike ethylene glycol, propylene glycol is of very low toxicity in vivo. In this study, propylene ...
Roy David A - - 2013
Aims: The aim of this study was to evaluate the safety and performance of a specifically designed, dedicated TAVI guidewire. Methods and results: From May 2011 to August 2012, 39 consecutive patients referred for TAVI were prospectively enrolled in a first-in-man, open label, non-randomised feasibility study to evaluate the safety ...
Harrowfield Jack - - 2013
The synthesis in 1985 by the group led by Tony McKervey of numerous calix[4]arene derivatives capable of acting as neutral, multidentate ligands proved to be a seminal step in the development of various applications of calixarenes as metal-ion binding agents.
Michele Lorenzo Di - - 2013
In this article we review the latest achievements in understanding and controlling DNA-mediated interactions between colloidal particles. We report the results of experiments, theoretical studies and computer simulations designed to investigate interactions and aggregation/melting behaviour of DNA-functionalized colloids. The unprecedented insight into the physical effects influencing the interactions and their ...
Texter John - - 2013
Autocondensation of organoalkoxysilanes, and subsequent anion exchange, produces organosiloxane supramolecular liquids, which are core-free and solvent-free nanoparticle nanofluids. This hybrid supramolecular liquid, [C(81) H(156) NO(3) S(SiO([2>x>3/2]) )](y) , exhibits(see TEM image; 200 nm width) interparticle menisci and softness (from imputed deformations) of interparticle potential.
Zhong Yuesi - - 2013
α-Melanocyte-stimulating hormone (α-MSH) functions as a mediator of inflammation and immunity; however, the short half-life and high dose needed limit the comprehensive clinical application of α-MSH. The aim of this study was to generate human bone marrow-derived mesenchymal stem cells (MSCs) that express and secrete high levels of bioactive α-MSH. ...
Slowinska-Klencka Dorota - - 2013
OBJECTIVE: New classification of the thyroid FNAB results tries to stratify the risk of malignancy of thyroid follicular lesions by using "follicular lesion of undetermined significance" (FLUS) subcategory. Clinical significance of this category in the endemic (or post-endemic) areas has not been clearly established. DESIGN: The aim of the study ...
Rodrigues J N B - - 2013
We develop an analytical scattering formalism for computing the transmittance through periodic defect lines within the tight-binding model of graphene. We first illustrate the method with a relatively simple case, the pentagon-only defect line. Afterwards, more complex defect lines are treated, namely the zz(558) and the zz(5757) ones. The formalism ...
Maddalena Victor - - 2013
PURPOSE: To assess, using qualitative methods, the knowledge African Canadians living in Nova Scotia have regarding their options for palliative and end-of-life (EOL) care. DESIGN: This project engaged caregivers in a Black community in Nova Scotia, Canada, in an exploration of palliative and EOL care. A group of six caregivers ...
Li Xiangyang - - 2013
The study investigates the complexes formed between sodium caseinate (SC) and sugar beet pectin (SBP) and to harness them to stabilize SBP emulsions. We find that both hydrophobic and electrostatic interactions are involved in the complexation. Soluble SC/SBP complexes are formed at pHc and insoluble complexes at pHφ and the ...
Perkins Keith - - 2013
Two-dimensional materials such as graphene show great potential for future nanoscale electronic devices. The high surface-to-volume ratio is a natural asset for applications such as chemical sensing, where perturbations to the surface resulting in charge redistribution are readily manifested in the transport characteristics. Here we show that single monolayer MoS2 ...
Chinsamy Anusuya - - 2013
Hundreds of specimens of the beaked bird Confuciusornis sanctus have been recovered from Early Cretaceous lake deposits of northeastern China. These birds show remarkable variation in size and plumage, with some displaying two long, central ornamental rectrices (tail feathers) and others lacking them altogether. Although, traditionally specimens with ornamental rectrices ...
Artal Mariana Coletty - - 2013
Nanomaterials are used in a wide spectrum of applications, including nanowires that are objects with at least one of its dimensions in the range of 1 to 100 nm. Recently, a new type of silver vanadate nanowire decorated with silver nanoparticles (SVSN-LQES1) with promising antimicrobial activity against different pathogenic bacteria ...
Que Long - - 2013
Micropatterns of the nanostructured aluminum oxide (NAO) with sizes from 5 µm to 200 µm have been successfully fabricated on the indium tin oxide (ITO) glass substrate by simply combining a lift-off process and a one-step anodization process for the first time. The detection of fluorescent dyes and biomolecules tagged ...
Yemshanov Denys - - 2013
Invasive species risk maps provide broad guidance on where to allocate resources for pest monitoring and regulation, but they often present individual risk components (such as climatic suitability, host abundance, or introduction potential) as independent entities. These independent risk components are integrated using various multicriteria analysis techniques that typically require ...
Brice Alejandro E - - 2013
This study explored the developmental trends and phonetic category formation in bilingual children and adults. Participants included 30 fluent Spanish-English bilingual children, aged 8-11, and bilingual adults, aged 18-40. All completed gating tasks that incorporated code-mixed Spanish-English stimuli. There were significant differences in performance according to phonotactic construction of the ...
Changenet-Barret Pascale - - 2013
Doxorubicin (DOX) is a potent anti-tumoral agent widely used for cancer therapy. Despite numerous studies, the fluorescence properties of DOX, usually exploited for the characterization of the interaction with biological media, have until now led to controversial interpretations, mainly due to self-association of the drug in aqueous solution. We present ...
Dangas George D - - 2013
Aims: Rates of stent thrombosis (ST) after ST-elevation myocardial infarction (STEMI) may vary over time and the relationship of this complication with non-adherence to dual antiplatelet therapy (DAPT) during long-term follow-up remains unclear. Methods and results: We analysed 2,997 patients who were treated with at least one stent and in ...
Takeda Noriyo - - 2013
Oocyte maturation and subsequent spawning in hydrozoan jellyfish are generally triggered by light-dark cycles. To examine if the initiation of the maturation process after light stimulus is mediated by neurotransmitters, neuropeptides isolated originally from Hydra magnipapillata were applied to sexually mature female medusae of the hydrozoan jellyfish Cytaeis uchidae. Among ...
Dolgin B - - 2013
Magnetic properties of basically antiferromagnetic La(0.23)Ca(0.77)MnO(3) particles with average sizes of 12 and 60 nm have been investigated in a wide range of magnetic fields and temperature. Particular attention has been paid to magnetization dynamics through measurements of the temperature dependence of ac-susceptibility at various frequencies, the temperature and field dependence ...
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