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Berry Jay G JG Division of General Pediatrics, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA. - - 2013
Readmission rates are used as an indicator of the quality of care that patients receive during a hospital admission and after discharge. To determine the prevalence of pediatric readmissions and the magnitude of variation in pediatric readmission rates across hospitals. We analyzed 568,845 admissions at 72 children's hospitals between July ...
Brock Jane J Colorado Foundation for Medical Care, Englewood, - - 2013
Medicare beneficiaries experience errors during transitions among care settings, yielding harms that include unnecessary rehospitalizations. To evaluate whether implementation of improved care transitions for patients with Medicare fee-for-service (FFS) insurance is associated with reduced rehospitalizations and hospitalizations in geographic communities. Quality improvement initiative for care transitions by health care and ...
Vashi Anita A AA Robert Wood Johnson Foundation Clinical Scholars Program, Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA. - - 2013
Current efforts to improve health care focus on hospital readmission rates as a marker of quality and on the effectiveness of transitions in care during the period after acute care is received. Emergency department (ED) visits are also a marker of hospital-based acute care following discharge but little is known ...
Dharmarajan Kumar K Division of Cardiology, Department of Internal Medicine, Columbia University Medical Center, New York, New York, - - 2013
To better guide strategies intended to reduce high rates of 30-day readmission after hospitalization for heart failure (HF), acute myocardial infarction (MI), or pneumonia, further information is needed about readmission diagnoses, readmission timing, and the relationship of both to patient age, sex, and race. To examine readmission diagnoses and timing ...
De Preeti - - 2013
ABSTRACT: BACKGROUND: Smoking is common in people infected with HIV but cessation support is not a routine part of clinical care. The aim was to assess whether smoking is a risk factor for pneumonia in people with HIV and whether smoking cessation ameliorates excess risk. METHODS: We performed MEDLINE and ...
Domaille Dylan W - - 2013
We report the synthesis, characterization, and protein sensing capabilities of M13 bacteriophage-DNA bioconjugates. DNA oligonucleotides were conjugated to M13 through acyl hydrazone linkages. In one case, DNAzymes retained their catalytic ability when anchored to the virus coat, and in a separate study, the dynamic nature of the hydrazone allowed for ...
Rydberg Patrik - - 2013
Three different types of atom accessibility descriptors are investigated in relation to site of metabolism predictions. To enable the integration of local accessibility we have constructed 2DSASA, a method for the calculation of the atomic solvent accessible surface area that is independent of 3D coordinates. The method was implemented in ...
Tongo Marcel - - 2013
ABSTRACT: BACKGROUND: Cameroon, in west central Africa, has an extraordinary degree of HIV diversity, presenting a major challenge for the development of an effective HIV vaccine. Given the continuing need to closely monitor the emergence of new HIV variants in the country, we analyzed HIV-1 genetic diversity in 59 plasma ...
Gnecco Giorgio - - 2013
Kernel machines traditionally arise from an elegant formulation based on measuring the smoothness of the admissible solutions by the norm in the reproducing kernel Hilbert space (RKHS) generated by the chosen kernel. It was pointed out that they can be formulated in a related functional framework, in which the Green's ...
Terazzi Emmanuel - - 2013
Single molecule magnets may be considered for the construction of future integrated nanodevices, provided however that some degree of ordering is imparted to these molecules (e.g. long-range nano-structuration on surfaces). Combining such magnetic nanometric objects with liquid-crystalline orderings to control their assembly and to potentially address them individually therefore appears ...
Oliver Lisa - - 2013
We have recently shown that the in vitro differentiation of human mesenchymal stem cells (hMSCs) was accompanied by an increased sensitivity toward apoptosis; however, the mechanism responsible for this shift is not known. Here, we show that the repair of DNA double-strand breaks (DSBs) was more rapid in undifferentiated hMSCs ...
Miller T A - - 2013
Superionic materials are multi-component solids with simultaneous characteristics of both a solid and a liquid. Above a critical temperature associated with a structural phase transition, they exhibit liquid-like ionic conductivities and dynamic disorder within a rigid crystalline structure. Broad applications as electrochemical storage materials and resistive switching devices follow from ...
Richards D - - 2013
In the past few years, mathematical modeling approaches in biology have begun to fulfill their promise by assisting in the dissection of complex biological systems. Here, we review two recent examples of predictive mathematical modeling in plant biology. The first involves the quantitative epigenetic silencing of the floral repressor gene ...
Suzuki Tomoyuki - - 2013
AIMS: Na(+) channel blockers are often used to treat atrial fibrillation (AF), but may sometimes cause ventricular contractile dysfunction. However, amiodarone, a multi-channel blocker with Na(+) channel block, causes less contractile dysfunction. In this study we tested the hypothesis that Na(+) channel block by amiodarone is selective in atrial myocytes ...
Pointillart Fabrice - - 2013
Centro-symmetric dinuclear complexes of formula [Ln(tta)(3)(L)](2)·xCH(2)Cl(2), (tta(-) = 2-thenoyltrifluoroacetonate anion, x = 0.5 for Ln = Eu (1a), Tb (3), and Dy (4) and x = 0 for Ln = Eu (1b) and Nd (2)) have been synthesized using the tetrathiafulvalene-3-pyridine-N-oxide as a bridging ligand (L). X-ray structures have shown ...
Hémont Caroline - - 2013
Human blood DCs encompass pDCs and two subsets of mDCs: CD1c(+) mDCs and CD141(+) mDCs. The rare CD141(+) DC population is thought to be the equivalent of mouse CD8α(+) cDCs that play a significant role in antigen cross-presentation. Here, we analyzed by Q-PCR TLR1-10 expression in blood DC subsets. Whereas ...
Ciuladaite Zivile - - 2013
Developmental delay and brain anomalies leading to significant morbidity and mortality are frequently caused by chromosomal rearrangements. We report on a familial unbalanced translocation resulting in distal monosomy 5p15.3-pter with trisomy 12q24.2-qter in 2 half siblings with cerebral dysgenesis, severe intellectual disability, dysmorphic features, progressive weakness, and atrophy of muscles.
Yan Ling - - 2013
Portable devices with advantages of rapid, on-site, user-friendly and cost-effective assessment are widely applied in our daily life. However, only a limited number of quantitative portable devices are commercially available, among which personal glucose meter (PGM) is the most successful example and has been the most widely used. However, PGM ...
Terek Demet - - 2013
Maple syrup urine disease (MSUD) is a rare inherited metabolic disorder resulting from the defective activity of branched-chain 2-ketoacid dehydrogenase complex. Routine screening of newborn with tandem mass spectroscopy on the third day of life may detect elevated branched-chain amino acids in blood before the appearance of encephalopathic symptoms in ...
Daneault Beoit - - 2013
BACKGROUND: PARAVALVULAR REGURGITATION (PVR) IS COMMON AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR) AND MAY BE ASSOCIATED WITH ADVERSE OUTCOMES. POSTDILATATION (PD) HAS BEEN PROPOSED TO TREAT PVR WITHOUT BEING FORMALLY STUDIED. WE PERFORMED A STUDY TO EVALUATE THE SAFETY AND EFFICACY OF PD AFTER BALLOON EXPANDABLE TAVR.METHODS AND RESULTS: CONSECUTIVE ...
Soon Wendy Weijia - - 2013
Advances in genome sequencing have progressed at a rapid pace, with increased throughput accompanied by plunging costs. But these advances go far beyond faster and cheaper. High-throughput sequencing technologies are now routinely being applied to a wide range of important topics in biology and medicine, often allowing researchers to address ...
Wall Geoffrey C - - 2013
Introduction: Educational activities should be developed to teach residents how to constructively interact with pharmaceutical representatives and how to critically assess the provided information.Methods: An educational study was implemented during the 2010-2011 academic year in an internal medicine residency program. The study included an initial educational session on physician-industry relations ...
Kurose Yuko - - 2013
ABSTRACT: BACKGROUND: Galectin-9 (Gal-9) induces apoptosis in activated T helper 1 (TH1) cells as a ligand for T cell immunoglobulin mucin-3 (Tim-3). Gal-9 also inhibits the G1 phase cell cycle arrest and hypertrophy in db/db mice, the hallmark of early diabetic nephropathy, by reversing the high glucose-induced up-regulation of cyclin ...
Li Yang - - 2013
The solvent effect on the luminescence properties of highly stable water-soluble silver nanoclusters is discussed in this study. The polymer nanosphere templates swollen by organic solvents lead to the changes in the surrounding environments of silver nanoclusters, thus resulting in a significant influence on their luminescence.
Ichikawa Satoshi - - 2013
Triazole-cross-linked oligodeoxynucleotides were synthesized using the Cu(I) catalyzed alkyne-azide cycloaddition with tris(azidoethyl)amine hydrochloride and oligodeoxynucleotides possessing N-3-(propargyl)thymidine at both the 3'- and 5'-termini. Further installation of a functional molecule to the dumbbell oligodeoxynucleotides was achieved by utilizing the remaining azide group.
Raza Syed Raza Ali - - 2013
We have fabricated transparent top-gate ZnO nanowire (NW) field effect transistors (FETs) on glass and measured their trap density-of-states (DOS) at the dielectric/ZnO NW interface with monochromatic photon beams during their operation. Our photon-probe method showed clear signatures of charge trap DOS at the interface, located near 2.3, 2.7, and ...
Maddox Michael - - 2013
INTRODUCTION: Despite the abundant data on outcomes following robotic assisted radical prostatectomy (RARP), no study has compared outcomes between an anterior versus posterior approach. We postulated that a posterior approach may facilitate dissection and lead to improved outcomes in patients with larger prostate glands. METHODS: After IRB approval, 404 patients ...
Decarolis Boris - - 2013
PURPOSERadioiodinated metaiodobenzylguanidine ((123)I-mIBG) scintigraphy is an established imaging method in neuroblastoma. Semiquantitative scoring systems have been developed to assess the extent of disease and response to chemotherapy. We present the results of the comparison between the SIOPEN [International Society of Pediatric Oncology Europe Neuroblastoma Group] score and the modified Curie ...
Trost Brett - - 2013
MOTIVATION: Phosphorylation is the most important post-translational modification in eukaryotes. While many computational phosphorylation site prediction tools exist for mammals, and a few were created specifically for Arabidopsis thaliana, none are currently available for other plants. RESULTS: In this paper, we propose a novel random forest-based method called SAPHIRE (SAskatchewan ...
Ni Lili - - 2013
Abstract Objective: To compare the influence of various tubal surgeries to ovarian reserve via serum level of antimullerian hormone (AMH) and the subsequent in vitro fertilization and embryo transplantation (IVF-ET) outcome in patients with simple tubal infertility. Study design: A prospective cohort study was conducted on 134 IVF cycles undegone ...
Fang Ming - - 2013
Collagen molecules, self-assembled into macroscopic hierarchical tissue networks, are the main organic building block of many biological tissues. A particularly common and important form of this self-assembly consists of type I collagen fibrils, which exhibit a nanoscopic signature -D-periodic gap/overlap spacing - with a distribution of values centered at approximately ...
Liu Yinping - - 2013
A simultaneous and fast determination of 18 phthalate esters (PAEs) in edible vegetable oils was developed. After solvent extraction, the PAEs in oil sample were further cleaned up by solid phase extraction. After concentration, the extract was directly injected into gas chromatography tandem mass spectrometry (GC-MS/MS) in positive ion (EI) ...
Solecki Gergely Morten - - 2013
Prostaglandins are endogenous mediators formed from arachidonic acid by cyclooxygenases and prostaglandin synthases during inflammatory processes. The five-membered ring can be dehydrated, and α,β-unsaturated cyclopen-tenone PGs (cyPGs) are generated. Recent studies have been focused on their potential pharmacological use against inflammation and cancer. However, little is known so far about ...
Frazzitta Marie A - - 2013
PurposeHealthy Babies Need Healthy Moms (HBNHM) is an innovative education program that combines the recommended 2-hour postpartum oral glucose tolerance test (OGTT) with diabetes prevention education for women who had gestational diabetes mellitus. During the class, the 2-hour OGTT is performed, and in the time between venipunctures, the women participate ...
Schwinghammer Katharina - - 2013
A new dimension: The doping of amorphous poly(triazine imide) (PTI) through ionothermal copolymerization of dicyandiamide with 4-amino-2,6-dihydroxypyrimidine (4AP) results in triazine-based carbon nitrides with increased photoactivity for water splitting compared to crystalline poly(triazine imide) (PTI/Li(+) Cl(-) , see picture) and melon-type carbon nitrides. This family of carbon nitride semiconductors has ...
Snow David P - - 2013
This article describes the development of intonation in 12 cochlear implant (CI) recipients. In a previously reported study of the first year of CI use, children who were implanted late (after 24 months) acquired intonation more rapidly than the younger participants. The older children's advantage is plausibly owing to their ...
Saracut Vasile - - 2013
The ability of metallic nanostructures to support surface plasmon excitations is widely exploited nowadays for developing new technologies and applications in many fields, like communications, medicine or environment. It is known that the plasmonic response of a nanostructure is strongly dependent on its size and shape, and thus a fine ...
Bu Wei - - 2013
A new bolaamphiphile comprising a 5,5'''''-diphenyl-sexithiophene core with glycerol groups at each end and four lateral decyl chains was synthesized, which self-assembles into a liquid crystalline phase representing a nanoscale honeycomb composed of quasi-infinite triangular cylinders of π-conjugated sexithiophenes.
Lippold Carsten - - 2013
ABSTRACT: BACKGROUND: The aim of this randomised clinical trial was to assess the effect of early orthodontic treatment in contrast to normal growth effects for functional unilateral posterior crossbite in the late deciduous and early mixed dentition by means of three-dimensional digital model analysis. METHODS: This randomised clinical trial was ...
Liu Wende - - 2013
Rice blast, caused by the fungal pathogen Magnaporthe oryzae, is one of the most devastating diseases of rice worldwide. The rice-M. oryzae pathosystem has become a model in the study of plantfungal interactions because of its scientific advancement and economic importance. Recent studies have identified a number of new pathogen-associated ...
Guha Nilabja - - 2013
The article proposes and investigates the performance of two Bayesian nonparametric estimation procedures in the context of benchmark dose estimation in toxicological animal experiments. The methodology is illustrated using several existing animal dose-response data sets and is compared with traditional parametric methods available in standard benchmark dose estimation software (BMDS), ...
Tauber Katharina - - 2013
Various artificial network designs that involve biocatalysts were tested for the asymmetric amination of sec-alcohols to the corresponding α-chiral primary amines. The artificial systems tested involved three to five redox enzymes and were exemplary of a range of different sec-alcohol substrates. Alcohols were oxidised to the corresponding ketone by an ...
Kuo Rei-Lin - - 2013
ABSTRACT: Enterovirus 71 (EV71) is an important human pathogen which may cause severe neurological complications and death in children. The virus caused several outbreaks in the Asia-Pacific region during the past two decades and has been considered a significant public health problem in the post-poliovirus eradication era. Unlike poliovirus, there ...
Tagalakis Aristides D - - 2013
Efficient delivery of siRNA remains the greatest technological barrier to the clinical implementation of RNA interference strategies. We are investigating the relationship between the biophysical properties of siRNA nanocomplexes and their transfection efficiency as an approach to the generation of improved formulations. Peptide based formulations are of great interest and ...
Grootendorst Diederik J - - 2013
The ability to accurately detect tumor metastases in lymph nodes is essential for intra-operative staging of various malignancies. Histopathological assessment of nodes has the drawback of a time delay before results are available to the surgeon and a likelihood of missing metastases. Photoacoustic (PA) imaging has been shown to possess ...
Chen Y Z - - 2013
The discovery of two-dimensional electron gases at the heterointerface between two insulating perovskite-type oxides, such as LaAlO(3) and SrTiO(3), provides opportunities for a new generation of all-oxide electronic devices. Key challenges remain for achieving interfacial electron mobilities much beyond the current value of approximately 1,000 cm(2) V(-1) s(-1) (at low temperatures). Here we ...
Matsumoto Shoji - - 2013
The reaction of o-alkynylarenesulfoxide with iodine was investigated in detail, revealing functionalities of the formation of alpha-diketones with sulfenyl, sulfinyl, and sulfonyl. Additives can change the ratio of products to give medium-to-excellent yields. Results show that water is taken into only sulfonyl compound and that other oxygen atoms constructed in ...
Tian Lijin - - 2013
Photosystems I (PSI) and II (PSII) are two major pigment-protein complexes of photosynthetic organisms that function in series to convert sunlight energy into chemical energy. We have studied the picosecond fluorescence behaviour of the core of both photosystems in vivo by using two Synechocystis PCC 6803 mutants: BE cells contain ...
Chen Guanying - - 2013
Nanophotonics is an emerging science dealing with the interaction of light and matter on a nanometer scale and holds promise to produce new generation nanophosphors with highly efficient frequency conversion of infrared (IR) light. Scientists can control the excitation dynamics by using nanochemistry to produce hierarchically built nanostructures and tailor ...
Celebi Kemal - - 2013
It has been claimed that graphene growth on copper by chemical vapor deposition is dominated by crystallization from the surface initially supersaturated with carbon adatoms, which implies that the growth is independent of hydrocarbon addition after the nucleation phase. Here, we present an alternative growth model based on our observations ...
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