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Saukko Paula - - 2013
Direct-to-consumer (DTC) genetic tests have aroused controversy. Critics have argued many of the tests are not backed by scientific evidence, misguide their customers and should be regulated more stringently. Proponents suggest that finding out genetic susceptibilities for diseases could encourage healthier behaviours and makes the results of genetics research available ...
Zeng Kun - - 2013
OBJECTIVE: To develop a rapid multi-residue assay for detecting 16 demanded by the European Union (EU). METHODS: A recombinant penicillin-binding protein (PBP) 2x* from Streptococcus pneumoniae R6 was expressed in vitro and six β-lactams were conjugated to HRP by four methods. A rapid multi-residue assay for β-lactams was established with ...
Takahashi Koji - - 2013
Pulmonary venoocclusive disease, classified as a subgroup of pulmonary arterial hypertension, is known to show poor prognosis and lung transplantation is the only possible treatment. Single living-donor lobar lung transplantation is a unique method of treatment, mostly for small children, and size matching is the most important factor to conduct ...
Stumbo Phyllis J - - 2013
Methods for conducting dietary assessment in the United States date back to the early twentieth century. Methods of assessment encompassed dietary records, written and spoken dietary recalls, FFQ using pencil and paper and more recently computer and internet applications. Emerging innovations involve camera and mobile telephone technology to capture food ...
Mossner Maximilian - - 2013
Investigation of X-chromosome inactivation patterns (XCIP) by determination of differential CpG-methylation has been widely applied for investigation of female cell clonality. Using this approach the clonal origin of various tumours has been corroborated. Controversially, strong age-related increase of peripheral blood (PB) cell clonality in haematologically healthy female subjects was reported. ...
Ferragut Marta - - 2013
Background: Sexist attitudes are one of the factors that justify domestic violence. Positive psychology can provide keys to prevent sexist violence at an early age. Psychological values are a group of psychological strengths in a person's development. They provide important clues for the prevention of gender-based violence. Method: This study ...
Kuo Hsun-Nan - - 2013
A 58-year-old man with acute type B aortic dissection presented with right lower limb cyanosis, mesenteric ischemia, and acute renal failure. He was treated with extraanatomic right axillofemoral bypass surgery alone, recovered completely from renal, mesenteric, and lower extremity malperfusion shortly thereafter, and lived free of symptoms for the following ...
Pacelli Fabio - - 2013
Neoadjuvant chemoradiation (CRT), tailored mesorectal excision, and intraoperative radiotherapy (IORT) have become the leading measures for rectal cancer treatment. The objective of this study was to evaluate early and long-term results of a multimodal treatment model for rectal cancer followed by curative surgery. Prospectively collected hospital records of 338 patients ...
Gupta D K - - 2013
Every day it is easy to find news articles detailing the impact of drug shortages on patients. Where this was once only a concern of patients with rare, orphan diseases, it is now the concern of patients receiving even the most common chemotherapeutic regimens, the most efficacious antimicrobial therapy, or ...
Charidimou Andreas - - 2013
When most doctors encounter older patients with transient focal neurological symptoms, they usually suspect a diagnosis of transient ischemic attacks or some of their known mimics (including migraine auras or focal seizures). This article emphasizes new observations on transient focal neurological episodes in the context of cerebral amyloid angiopathy, a ...
Ogienko Anna A - - 2013
Capping protein (CP) is a well-characterised actin-binding protein important for regulation of actin filament (AF) assembly. CP caps the barbed end of AFs, inhibiting the addition and loss of actin monomers. In Drosophila melanogaster, the gene encoding CP β-subunit is named capping protein beta (cpb; see Hopmann et al. [1996] ...
Notebaert Anneleen - - 2013
We report on a 13-year-old boy who presented with signs suggestive of encephalitis and in whom magnetic resonance imaging revealed lesions in the genu and splenium of the corpus callosum and symmetrical lesions bilaterally in the center semiovale. This clinical-radiologic entity was previously reported in the literature and was given ...
Li Yan Hong - - 2013
OBJECTIVE: To study age and educational level and their relationship with fall-related injuries in Shanghai and to analyze the relevant costs. METHODS: Multistage cluster sampling was used for the selection of participants and standardized questionnaires were used for the information collection in 2006. Information on cases and deaths caused by ...
Allen Mark S - - 2013
At the 25th Annual General Thoracic Surgical Club meeting in March 2012, the major cooperative groups presented updates on clinical trials at the Robert Ginsberg Clinical Trials Meeting. There were 57 members in attendance. Representatives from the Radiation Treatment Oncology Group (RTOG), American College of Surgeons Oncology Group (ACOSOG), Cancer ...
M Cárdaba Miguel A - - 2013
Background: The purpose of this study was to examine the role of thinking in reducing prejudice toward stigmatized groups. Method: Participants received a persuasive message composed of strong arguments in favor of South American immigrants or a control message. In order to distinguish high- from low-elaboration individuals, participants were asked ...
Sharkey Siobhan - - 2013
PURPOSE:: To enhance the learner's competence with information about a study examining nursing home factors associated with the On-Time Quality Improvement for Pressure Ulcer Prevention program clinical decision support tools. TARGET AUDIENCE:: This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. ...
Saraiya Hemant A - - 2013
: Negative-pressure wound therapy (NPWT) is a well-known treatment modality for chronic, difficult, nonhealing wounds. Unfortunately, many commercially available negative-pressure therapy systems for wounds are expensive, require hospitalization, and may not be available throughout the world. The authors have designed a less expensive and effective NPWT system from components readily ...
Tsai Meng-Ta - - 2013
Surgical repair of a left ventricular pseudoaneurysm is challenging. Percutaneous closure with an AMPLATZER Septal Occluder (AGA Medical Corporation, Golden Valley, MN) has evolved to be an effective alternative to conventional surgery with less complication. We report a case of severe hemolytic hyperbilirubinemia and acute renal failure after percutaneous left ...
Orman Gunes - - 2013
Pulmonary artery aneurysms are rare pathologic conditions of the thoracic cavity. The ─▒diopathic form of the disease is reported very rarely. We report the case of a 16-year-old girl with idiopathic pulmonary artery aneurysm with surface rendered 3-dimensional images of 64-slice computed tomography. A right-sided aortic arch with normal aortic ...
Xu Fang - - 2013
Adventitial fibroblasts (AFs) are the main cell type in the adventitia, however, their role in atherosclerosis remains unclear. We have investigate the role of AFs in atherosclerotic lesion formation by comparing the characteristics of AFs from apoE(-/-) to C57BL/6 mice. A minority of AFs from apoE(-/-) mice expressed α-SM-actin, but ...
Del Río Ferres Eva - - 2013
Background: Studies conducted in several countries have documented that women with disabilities are more vulnerable to experience gender-based violence than women without disabilities. Method: A total of 96 women, 45 with visual disabilities and 51 with physical disabilities, were interviewed to determine the prevalence of violence and its possible relations ...
Song Er Qun - - 2013
OBJECTIVE: To compare the nature of the metabolites formed from the phase I metabolism (hydroxylation and oxidation) and phase II metabolism (glutathionyl conjugation) of PCBs that have different chlorine substitution patterns. To discuss the structure-activity relationships and metabolic mechanisms of PCBs. METHODS: 4-Cl-biphenyl (PCB3), 4,4'-Cl-biphenyl (PCB15), 3,4,3',4'-Cl-biphenyl (PCB77) were used ...
Edmunds L Henry LH - - 2013
"Ben" Roe was the eighth president of The Society of Thoracic Surgeons. He was a fourth-generation native Californian, a hall of fame athlete, a pioneer in the development of cardiac surgery, and a crusading reformer of professional standards, education, and ethics. Educated in both northern California and in Boston, his ...
Zheng G G Department of Internal Medicine, University of Michigan, Ann Arbor, MI, - - 2013
Chronic psychological stress (CPS) is associated with increased intestinal epithelial permeability and visceral hyperalgesia. It is unknown whether corticosterone (CORT) plays a role in mediating alterations of epithelial permeability in response to CPS. Male rats were subjected to 1-h water avoidance (WA) stress or subcutaneous CORT injection daily for 10 ...
Garnett Tara - - 2013
The global food system makes a significant contribution to climate changing greenhouse gas emissions with all stages in the supply chain, from agricultural production through processing, distribution, retailing, home food preparation and waste, playing a part. It also gives rise to other major environmental impacts, including biodiversity loss and water ...
Vázquez González Fernando L - - 2013
Background: Despite depression being a common problem among nonprofessional caregivers, no studies of prevention of depression targeting this population exist in the literature. The studies of indicated prevention of depression aim of this study was to assess the efficacy of a problem-solving intervention in preventing clinical depression in a sample ...
Yilmaz Sanem - - 2013
Alagille syndrome is associated with various ocular abnormalities, including pseudopapilledema or optic disk edema due to increased intracranial pressure. Several mechanisms have been proposed to explain the mechanism of intracranial hypertension in Alagille syndrome. Craniosynostosis is an unusual but significant cause of increased intracranial hypertension in Alagille syndrome. It has ...
Ballesteros Soledad - - 2013
Background: In this study, we investigated the effects of normal and pathological (mild cognitive impairment, MCI) aging on several cognitive functions (processing speed, executive control and implicit memory). Method: Twenty young adults, 20 healthy older adults and 20 elders with MCI performed a series of cognitive tasks under controlled conditions. ...
Zagouri Flora - - 2013
The main indication of prophylactic mastectomy pertains to BRCA1 or BRCA2 mutation carriers. Prophylactic mastectomy includes the simple method and the subcutaneous method. Both methods can be followed by breast plastic reconstruction either at the same time or later. This review examines key issues regarding prophylactic mastectomy: the selection of ...
Wu Xiujun - - 2013
Purpose: To determine the allele frequency of three codon-changing variants (CYP2C8*2, CYP2C8*3, and CYP2C8*4) in the Han, Uighur, Hui, and Mongolian Chinese populations, and compare genetic polymorphism differences between the Han and minority Chinese ethnicities. Methods: Five hundred seventy four healthy unrelated volunteers from four major nationalities (Han: 136; Uighur: ...
Peña-Suárez Elsa - - 2013
Background: Organizational climate is the set of perceptions shared by workers who occupy the same workplace. The main goal of this study is to develop a new organizational climate scale and to determine its psychometric properties. Method: The sample consisted of 3,163 Health Service workers. A total of 88.7% of ...
Jia Xin - - 2013
This prospective multicenter comparative study examined early and midterm results of medication and stent-graft therapies on chronic type B aortic dissection in China. The study consisted of 303 consecutive patients with chronic type B aortic dissection from four centers in China from January 2007 to December 2010 who were prospectively ...
García-Llana Helena - - 2013
Background: A low rate of adherence to treatment is a widespread problem of great clinical relevance among dialysis patients. The objective of the present study is to determine the relationship between adherence, emotional state (depression, anxiety, and perceived stress), and health-related quality of life (HRQOL) in renal patients undergoing dialysis. ...
Kölbel Tilo - - 2013
A 67-year-old patient with severe comorbidities and acute type A aortic dissection with pericardial tamponade was treated with an endograft introduced through a mini-thoracotomy and puncture of the left ventricular apex. Final angiography showed complete coverage of the dissection. Early and 6-month follow-up computed tomography showed full apposition of the ...
Fälth Linda L Linnaeus University, Växjö, Sweden. - - 2013
The purpose of the present study was to examine the effects of three computerized interventions on the reading skills of children with reading disabilities in Grade 2. This longitudinal intervention study included five test sessions over 1 year. Two test points occur before the intervention, and three afterwards. The last ...
Cavanna Andrea E - - 2013
Tourette syndrome is a neurodevelopmental disorder characterized by multiple tics and is often associated with comorbid behavioral problems. Research with generic instruments in child populations showed that comorbid disorders can have a greater impact on health-related quality of life than tic severity. This study investigated the usefulness of a newly ...
Stephen Alison M - - 2013
The aim of this paper is to describe innovations taking place in national nutrition surveys in the UK and the challenges of undertaking innovations in such settings. National nutrition surveys must be representative of the overall population in characteristics such as socio-economic circumstances, age, sex and region. High response rates ...
Lynn Elizabeth T - - 2013
Although computed tomography (CT) scans play an important role in the diagnosis and management of anastomotic leaks (AL), there is no consensus on what radiographic findings are associated with AL. The purpose of this study is to identify the most common CT scan findings associated with AL and whether the ...
Hoganson David M - - 2013
Neonates who experience respiratory failure despite maximal ventilatory support have only extracorporeal membrane oxygenation as a rescue therapy, but it has very poor outcomes as a bridge to transplantation. A pumpless lung-assist device has been used in adults as a bridge to lung transplantation. An alternative membrane oxygenator, the Quadrox ...
Sinha Sidhartha S St. George's Vascular Institute, St. George's Healthcare NHS Trust, London, United Kingdom. - - 2013
Junctional vascular trauma such as that at the thoracic outlet poses particular challenges in surgical management. The use of endovascular techniques for such injuries is attractive as repair may be facilitated without the need for thoracotomy; however, the utility of such techniques is currently based on opinion, small retrospective series, ...
Ruiz Francisco J - - 2013
Background: Experiential avoidance and psychological inflexibility have been recently found to be important constructs related to a wide range of psychological disorders and quality of life. The current study presents psychometric and factor structure data concerning the Spanish translation of a general measure of both constructs: the Acceptance and Action ...
Young Andrew Joseph - - 2013
Bladder pressure measurements (BPMs) are considered a key component in the diagnosis of abdominal compartment syndrome (ACS). The purpose of this observational review was to determine risk factors of ACS and associated mortality with particular focus on the role of BPM. A retrospective trauma registry and chart review was performed ...
Usui Akihiko - - 2013
We developed a needle stick technique for treating hypertrophic obstructive cardiomyopathy. Three 21-gauge needles are inserted into the interventricular septum just below the aortic valve annulus beyond the far side of the septal bulge. The right and left needles are both side margins, and the center needle is a guide ...
van Venrooij Lenny M W - - 2013
Loss of body tissue resulting in undernutrition can be caused by reduced food intake, altered metabolism, ageing, and physical inactivity. The predominant cause of undernutrition before cardiac operations is unknown. First, we explored the association of reduced food intake and inactivity with undernutrition in patients before elective cardiac operations. Second, ...
Esplin Brandt L - - 2013
Amyloidosis is a rare disease in which insoluble extracellular protein fibrils in β-pleated sheets infiltrate multiple organs, causing organ dysfunction and failure. Amyloidoses are generally classified into light chain or primary systemic amyloidosis, hereditary amyloidosis (most commonly, transthyretin amyloidosis), senile systemic amyloidosis, secondary amyloidosis, and isolated atrial amyloidosis. At least ...
Sallevelt Suzanne C E H - - 2013
Mitochondrial or oxidative phosphorylation diseases are relatively frequent, multisystem disorders; in about 15% of cases they are caused by maternally inherited mitochondrial DNA (mtDNA) mutations. Because of the possible severity of the phenotype, the lack of effective treatment, and the high recurrence risk for offspring of carrier females, couples wish ...
Alzate Mónica - - 2013
Background: The concept of Reconciliation as applied to inter-group conflict has come into use only recently. Throughout the history of Psychology, Reconciliation was mostly understood at the individual and inter-personal level. Method: In the present study we shall analyse the roles played by trust, negotiating attitude, legitimacy and ethnocentric attitude ...
Shetty Prathibha - - 2013
Mesenchymal stem cells (MSCs) could be an alternative to foetal cells in the treatment of several neurodegenerative diseases, especially Parkinson's disease (PD). We have previously demonstrated the functional efficacy of the undifferentiated bone marrow MSCs (BMMSCs) cultured in a xenofree conditions in PD animal models. We now demonstrate isolation of ...
Luke Rebecca R - - 2013
We report a patient with Sturge-Weber syndrome without facial angioma, who presented with seizures and normal initial imaging results. The patient experienced several years without seizures before a sudden increase in seizure frequency, followed by an atypical evolution of imaging findings prompting biopsy to establish the diagnosis. This case highlights ...
Greer Lauren T - - 2013
The colon is the second most commonly injured intra-abdominal organ in penetrating trauma. Management of traumatic colon injuries has evolved significantly over the past 200 years. Traumatic colon injuries can have a wide spectrum of severity, presentation, and management options. There is strong evidence that most non-destructive colon injuries can ...
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