Search Results
Results 601 - 650 of 2387
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Steele Catriona M - - 2013
The purpose of this study was to measure treatment outcomes in a group of six adults with chronic dysphagia following acquired brain injury, who each completed 24 sessions of tongue-pressure resistance training, over a total of 11-12 weeks. The treatment protocol emphasized both strength and accuracy. Biofeedback was provided using ...
Concannon E - - 2013
BACKGROUND: The National Cancer Strategy heralded a major reorganisation of the delivery of cancer services in Ireland. As a result of this policy, cancer care was centralised to eight centres. The impact of this strategy on hospitals no longer providing cancer services has not been analysed to date. AIM: The ...
Ben Hassine Sihem - - 2013
Human serum samples (n = 113) from Bizerte, northern Tunisia, collected between 2011 and 2012 were analyzed for 8 organochlorine pesticides (OCPs) including p,p'-dichlorodiphenyltrichloroethane (DDT) and its metabolites, hexachlorobenzene (HCB), hexachlorocyclohexane isomers, dieldrin, and heptachlor and 12 polychlorinated biphenyls (PCBs) congeners. Concentrations of these residues in serum were determined by gas chromatography ...
Cramarossa Gemma - - 2013
OBJECTIVE: This study examined which domains/symptoms from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 15 Palliative (QLQ-C15-PAL), an abbreviated version of the health-related EORTC QLQ-C30 questionnaire designed for palliative cancer patients, were predictive of overall quality of life (QOL) in advanced cancer ...
Lamanauskas N - - 2013
Abstract Background: Cell exposure to ultrasound (US) in the presence of contrast agent microbubbles (MBs) can result in cell sonoporation that can be exploited for drug or gene delivery. Anticancer drug bleomycin (BLM), used in sonoporation, can effectively eliminate tumor cells in vitro and in vivo. Nevertheless, sonoporation mechanism is ...
Ananthakrishnan Ashwin N AN Crohn's and Colitis Center, Division of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA. - - 2013
Psychiatric comorbidity is common in Crohn's disease (CD) and ulcerative colitis (UC). Inflammatory bowel disease (IBD)-related surgery or hospitalizations represent major events in the natural history of the disease. The objective of this study is to examine whether there is a difference in the risk of psychiatric comorbidity following surgery ...
Waldman Elisha - - 2013
Over the past two decades, paediatric palliative care has emerged as both a primary approach and as its own medical subspecialty, the overall aim of which is to ease suffering for children with life-threatening illness and their families through a concurrent model of care. However, most discussions have been focused ...
Ahmed Anwar E - - 2013
In noninferiority studies, a limit of indifference is used to express a tolerance in results such that the clinician would regard such results as being acceptable or 'not worse'. We applied this concept to a measure of accuracy, the Receiver Operating Characteristic (ROC) curve, for a sequence of tests. We ...
Wang Jianmin - - 2013
Abstract Objective: The ultimate goal of this research is to corroborate the physicochemical characterization of nanostructured lipid carrier (NLC) loading unstable lipophilic active ingredients with an antioxidant function, such as alpha-lipoic acid (ALA), and monitoring its photochemical stability of ALA-NLC against natural daylight. NLC is an innovative active compound delivery ...
França R F O - - 2013
In recent years we have observed great advances in our ability to combat infectious diseases. Through the development of novel genetic methodologies, including a better understanding of pathogen biology, pathogenic mechanisms, advances in vaccine development, designing new therapeutic drugs, and optimization of diagnostic tools, significant infectious diseases are now better ...
CíΕΎ M - - 2013
Histamine exerts the capacity to influence the activity of immune cells including neutrophils and plays a pivotal role in inflammatory processes which are a complex network of cellular and humoral events. Since oxidative burst linked with the production of reactive oxygen species is a principal functional manifestation of activated neutrophils, ...
Kluger Benzi M BM Department of Neurology, University of Colorado Denver, Aurora, USA. - - 2013
Fatigue is commonly reported in many neurologic illnesses, including multiple sclerosis, Parkinson disease, myasthenia gravis, traumatic brain injury, and stroke. Fatigue contributes substantially to decrements in quality of life and disability in these illnesses. Despite the clear impact of fatigue as a disabling symptom, our understanding of fatigue pathophysiology is ...
Cray Jonathan A JA School of Biological Sciences, MBC, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, - - 2013
Competition between microbial species is a product of, yet can lead to a reduction in, the microbial diversity of specific habitats. Microbial habitats can resemble ecological battlefields where microbial cells struggle to dominate and/or annihilate each other and we explore the hypothesis that (like plant weeds) some microbes are genetically ...
Russo Giulio - - 2013
PURPOSE: To assess the effects of short-acting nitrates on exercise stress test (EST) results and the relation between EST results and coronary blood flow (CBF) response to nitrates in patients with microvascular angina (MVA). METHODS: We completed 2 symptom/sign limited ESTs on 2 separate days, in a random sequence and ...
Wu X - - 2013
The tree shrew (Tupaia belangeri chinensis) is a squirrel-like lower primate or a close relative of primates, commonly used as an animal model in biomedical research. Despite more than three decades of usage in research, the clear relationships between body weight, fasting blood glucose concentration, sex and age among tree ...
Zenaro Elena - - 2013
The migration of leukocytes from the bloodstream into the central nervous system (CNS) is a key event in the pathogenesis of inflammatory neurological diseases and typically involves the movement of cells through the endothelium of post-capillary venules, which contains intercellular tight junctions. Leukocyte trafficking has predominantly been studied in animal ...
Erkutlu Ibrahim - - 2013
Glioblastoma multiforme (GBM) is the most common and the most aggressive primary malignant tumor of the brain. Prognostic factors in GBM can be sorted as age, tumor localization, tumor diameter, symptom period and type, the extent of surgery, postoperative tumor volume, and adjuvant radiotherapy and/or chemotherapy status. Besides the interactions ...
Yang Cheng - - 2013
Context: The heart is one of the target organs susceptible to attack by sepsis, and protection of the cardiac function in sepsis or alleviation dysfunction caused by sepsis appears a serious and urgent problem. Objective: This study was designed to explore the effect of curcumin on myocardial injury induced by ...
Lertwattanasakul Noppon - - 2013
By random integrative mutagenesis with a kanMX4 cassette in Kluyveromyces marxianus DMKU 3-1042, we obtained three mutants of COX15, ATP25 and CYC3 encoding a cytochrome oxidase assembly factor (singleton), a transcription factor required for assembly of the Atp9p subunit of mitochondrial ATP synthase and cytochrome c heme lyase, respectively, as ...
Wu Ning - - 2013
Peanut is a major agronomic crop within the legume family and an important source of plant oil, proteins, vitamins, and minerals for human consumption, as well as animal feed, bioenergy, and health products. Peanut genomic research effort lags that of other legumes of economic importance, mainly due to the shortage ...
Glarner Carly E CE Department of Surgery, University of Wisconsin, Madison, WI, - - 2013
In the treatment of melanoma, inguinal lymph node dissection (ILND) is the standard of care for palpable or biopsy-proven lymph node metastases. Wound complications occur frequently after ILND. In the current study, the multicenter American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) was utilized to examine the ...
Tsourlakis M C - - 2013
Background:Neuron-glia-related cell-adhesion molecule (Nr-CAM) is another potential membrane-bound target molecule for specific prostate cancer therapy. The role of Nr-CAM in normal and neoplastic prostate tissue has not been extensively studied. The aim of our study is to evaluate the prevalence of Nr-CAM expression in prostate cancer and to explore its ...
Akikusa Jonathan D - - 2013
AIM: Acute gastroenteritis (AGE) has been a significant component of the clinical load in the short stay unit (SSU) at the Royal Children's Hospital (RCH) since its establishment in 2004. Since the introduction of routine rotavirus immunisation in Australia in 2007 there has been a clinical impression of a substantial ...
Tsagkataki Myrto - - 2013
Adenoviral (AdV) keratoconjunctivitis usually presents as a follicular conjunctivitis, with a pre-auricular lymphadenopathy and punctate epithelial keratitis. It is most commonly caused by adenoviral serotypes 8, 19, and 37 from subgenus D(1) . Most patients have a self-limited disease of one to two weeks duration and usually the virus cannot ...
Byrne Celia C Uniformed Services University of the Health Sciences, Bethesda, MD, - - 2013
Metalloestrogens are metals that activate the estrogen receptor in the absence of estradiol. The metalloestrogens fall into two subclasses: metal/metalloid anions and bivalent cationic metals. The metal/metalloid anions include compounds such as arsenite, nitrite, selenite, and vanadate while the bivalent cations include metals such as cadmium, calcium, cobalt, copper, nickel, ...
Sarikaya Hakan - - 2013
Stroke is a common cause of death and persisting disability worldwide, and thrombolysis with intravenous alteplase is the only approved treatment for acute ischaemic stroke. Older age is the most important non-modifiable risk factor for stroke, and demographic changes are also resulting in an increasingly ageing population. However, clinical trial ...
Eves Neil D - - 2013
The incremental changes made in the definition of ALI/ARDS over the last two decades represent a series of landmark events in the history of the condition. The first description of ARDS (Adult Respiratory Distress Syndrome) established the recognition of this syndrome(1) ; the 1994 AECC (America-European Consensus Conference) definition set ...
Wiersema A - - 2013
Aim. The aim of this study was to evaluate the current practice of the use of perioperative antithrombotic drugs to prevent arterial thrombo-embolic complications during arterial vascular surgery by Dutch vascular surgeons. Aim was also to compare the results with the literature and to evaluate the effect of guidelines. Methods. ...
Farombi Ebenezer O - - 2013
The beneficial effects of kolaviron, a natural biflavonoid from the seeds of Garcinia kola, have been attributed mainly to its antioxidant and anti-inflammatory effects. The present study investigated these effects on dextran sulphate sodium (DSS)-induced ulcerative colitis in rats. Sulfasalazine served as standard reference in this study. Kolaviron and sulfasalazine ...
Ghosh Arko - - 2013
Astrocytes play a crucial role in maintaining neuronal function and monitoring their activity. According to neuronal activity maps, the body is represented topographically in the somatosensory cortex. In rats, neighboring cortical areas receive forelimb (FL) and hindlimb (HL) sensory inputs. Whether astrocytic activity is also restricted to the cortical area ...
Hopwood Nick - - 2013
HOPWOOD N, FOWLER C, LEE A, ROSSITER C and BIGSBY M. Nursing Inquiry 2013 Understanding partnership practice in child and family nursing through the concept of practice architectures A significant international development agenda in the practice of nurses supporting families with young children focuses on establishing partnerships between professionals and ...
Kurita G P - - 2013
AIMS: This prospective, cross-sectional study aimed to assess cancer pain and its management in an inpatient setting at a comprehensive cancer centre in Denmark. METHODS: One hundred and eighty-eight inpatients with cancer were invited to participate (May/June 2011). Demographics, diagnoses, World Health Organization performance status, health-related quality of life, pain ...
Margalit R - - 2013
This qualitative study is intended to elucidate Lakota elders' views on traditional tobacco and commercial/addictive tobacco use, capturing the oral history that depict the cultural protocol regarding traditional tobacco, called Cansasa. Commercial tobacco use has significantly impacted the Northern Plains Indians. National surveillance systems report that tobacco use is more ...
Tseng Chia-Chen CC Department of Otolaryngology, National Taiwan University Hospital, Taipei, - - 2013
This study investigated the feasibility of the cervical vestibular-evoked myogenic potential (cVEMP) test using bone-conducted vibration (BCV) tapping. Prospective study. Initially, 20 healthy volunteers aged 23-38 years underwent cVEMP tests in supine position using head elevation method by BCV tapping at the Fz and inion. On another day, the same ...
Perfect John R - - 2013
Program overview The clinical care of seriously ill patients can often be complicated by invasive fungal infections that substantially increase morbidity and mortality. Early identification of these infections is paramount to successful clinical outcomes. Effective management of invasive fungal infections also requires individualized therapy that optimizes efficacy and safety. The ...
Ni Wentao - - 2013
ABSTRACT: BACKGROUND: Cryptococcosis is considered as an opportunistic infection because it mainly occurs in immunosuppressed hosts. C. neoformans usually acquired by the respiratory route and then may disseminate hematogenously to other places, such as meninges, bone and skin. Cutaneous involvement is a rare but important feature of disseminated cryptococcosis with ...
Vrieling Anton - - 2013
Frequent spatial reorganization of administrative units is common in many countries. It may comprise the merging or division of spatial units, or boundary changes between units. These reorganizations prevent the effective assessment of longer-term population dynamics at a detailed spatial level. To deal with this problem in the Netherlands, we ...
Li Peng - - 2013
Pattern synchronization (PS) can capture one aspect of the dynamic interactions between bivariate physiological systems. It can be tested by several entropy-based measures, e.g., cross sample entropy (X-SampEn), cross fuzzy entropy (X-FuzzyEn), multivariate multiscale entropy (MMSE), etc. A comprehensive comparison on their distinguishability is currently missing. Besides, they are highly ...
Brown A S - - 2013
Autism is a complex neuropsychiatric syndrome with a largely unknown etiology. Inflammation during pregnancy may represent a common pathway by which infections and other insults increase risk for the disorder. Hence, we investigated the association between early gestational C-reactive protein (CRP), an established inflammatory biomarker, prospectively assayed in maternal sera, ...
Marxen Julia C - - 2013
Haemocyanin (Hc) is a copper-containing respiratory protein, floating freely dissolved in the hemolymph of many arthropod species. A typical haemocyanin is a hexamer or oligohexamer of six identical or similar subunits, with a molecular mass around 75 kDa each. In the crustaceans, the haemocyanins appear to be restricted to the remipedes ...
Lee Ju-Hee - - 2013
BACKGROUND: Current sentinel node (SN) detection techniques require a learning period and tracers have many disadvantages for practical use. The purpose of this study was to evaluate the feasibility of preoperative computed tomography (CT) lymphography using lipiodol for detecting SNs in gastric cancer. METHODS: A total of 24 patients who ...
Kim J-W - - 2013
AIMS/HYPOTHESIS: The loss of beta cell function is a critical factor in the development of type 2 diabetes. Glucotoxicity plays a major role in the progressive deterioration of beta cell function and development of type 2 diabetes mellitus. Here we demonstrate that microRNA (miR)-30a-5p is a key player in early-stage ...
Wells Matthew - - 2013
BACKGROUND: Corneal pachymetry is an important aspect of modern eye care. This study aims to compare the measurement of central corneal thickness (CCT) using automated optical pachymetry, anterior segment optical coherence tomography (AS-OCT) and ultrasound. METHODS: Fifty volunteers participated in this study. Central corneal thickness was measured using the Topcon ...
Buchwald Henry - - 2013
BACKGROUND: Metabolic/bariatric procedures for the treatment of morbid obesity, as well as for type 2 diabetes, are among the most commonly performed gastrointestinal operations today, justifying periodic assessment of the numerical status of metabolic/bariatric surgery and its relative distribution of procedures. METHODS: An email questionnaire was sent to the leadership ...
Mor Z - - 2013
Immigration from high tuberculosis (TB) prevalence countries has a substantial impact on the epidemiology of TB in receiving countries with low TB incidence. Cross-border migration offers an ideal opportunity for active case finding that will result in a lower case load in the host country and a reduced spread of ...
Chin Joanna Y JY Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, - - 2013
Potentiating homologous recombination using triplex-forming peptide nucleic acids (PNAs) can be used to mediate targeted sequence editing by donor DNAs and thereby induce functional gene expression to supplant non-functional counterparts. Mutations that disrupt the normal function of the β-globin subunit cause hemoglobinopathies such as sickle cell disease and β-thalassemias. However, ...
Streck André Felipe - - 2013
In the present study, tonsils and hearts from 100 pigs were collected in a German slaughterhouse in 2010 and tested for porcine parvoviruses (PPV, PPV2, PPV3 and PPV4). PPV was observed in 60 of 100 hearts and 61 of 100 tonsils, and PPV2 was observed in 55 of 100 hearts ...
Yang Ilun - - 2013
The use of laparoscopic techniques in the treatment of colorectal diseases was first described in the early 1990s. Even though its clinical benefits have been well documented, laparoscopic colorectal surgery has been slow to gain adoption in the surgical community, given its technical demands. To help overcome these challenges while ...
Koda Masahiko - - 2013
BACKGROUND: Our aim was to determine how well ablative margin (AM) grading assessed by magnetic resonance imaging (MRI) with ferucarbotran administered prior to radiofrequency ablation (RFA) predicts local tumor progression in comparison with enhanced computed tomography (CT). METHODS: 101 hepatocellular carcinomas were treated by RFA after ferucarbotran administration. We performed ...
Brody Carinne Meyer - - 2013
Abstract One approach to delivering healthcare in developing countries is through voucher programmes, where vouchers are distributed to a targeted population for free or subsidised health care. Using inclusion/exclusion criteria, a search of databases, key journals and websites review was conducted in October 2010. A narrative synthesis approach was taken ...
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