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Results 401 - 450 of 4815
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Kanda J - - 2013
High fevers and/or rashes prior to neutrophil engraftment are frequently observed after umbilical cord blood (UCB) transplantation, and the condition is referred to as pre-engraftment syndrome (PES). Few studies have evaluated the risk factors for and treatment response to PES. Therefore, we retrospectively characterized PES in 57 consecutive engrafted patients ...
Ke Jing - - 2013
Termites are highly effective in lignocellulose degradation; however, the process of lignin deconstruction along the alimentary canal is not well understood. In this study, the wood metabolites in each gut segment were tentatively analyzed using pyrolysis gas chromatography mass spectrometry in presence of tetramethylammonium hydroxide. Collectively, the significant differences in ...
Qi Ji - - 2013
Monolithic hierarchical nanoporous gold disks, 500 nm in diameter, 75 nm in thickness and 3.5 nm in pore radius, have been fabricated by hybrid processes. A surface-enhanced Raman scattering enhancement factor of at least 10(8) has been obtained on individual disks using benzenethiol self-assembled monolayer with 785 nm laser excitation.
Akasaka Emiko - - 2013
Various therapies have been tried for psoriasis. In Japan, biologics began to be used for psoriasis treatment in January 2010. Their clinical efficacy is well known, but biologics cannot be used in all psoriasis patients for reasons such as side-effects and cost. It is necessary to evaluate the effect of ...
Ma Yanrui - - 2013
Peptides, proteins and extracellular matrix act synergistically to influence cellular function at the biotic-synthetic interface. However identifying the individual and cooperative contributions of the various combinations and concentration regimes is extremely difficult. The confined channel deposition method we describe affords highly tunable orthogonal reactive concentration gradients that greatly expand the ...
Hashemi Hassan - - 2013
BACKGROUND: The prevalence of myopia and hyperopia and determinants were determined in a rural population of Iran DESIGN: Population based cross sectional study. PARTICIPANTS: Using random cluster sampling, 13 of the 83 villages of Khaf County in the north east of Iran were selected. Data from 2001 people over the ...
Sassin Megan B - - 2013
The impressive specific capacitance and high-rate performance reported for many nanometric charge-storing films on planar substrates cannot impact a technology space beyond microdevices unless such performance translates into a macroscale form factor. In this report, we explore how the nanoscale-to-macroscale properties of the electrode architecture (pore size/distribution, void volume, thickness) ...
Gur-Yaish Nurit - - 2013
Objectives: To explore the effects of four types of support (psychological support, instrumental support, supervision of instrumental support, and explanation of medical care) on the level of depressive symptoms among hospitalized older adults. Method: The sample consisted of 468 older adults admitted to the internal medicine units of a large ...
Gupta Sharad S Department of Bioengineering, University of California, Riverside, Riverside, CA 92521, - - 2013
We report the first proof-of-principle demonstration of photoacoustic imaging using a contrast agent composed of a plant virus protein shell, which encapsulates indocyanine green (ICG), the only FDA-approved near infrared chromophore. These nano-constructs can provide higher photoacoustic signals than blood in tissue phantoms, and display superior photostability compared to non-encapsulated ...
Wijaya I M Mahaputra - - 2013
Photolyases (PHRs) utilize near UV/blue light to specifically repair the major photoproducts (PPs) of UV-induced damaged DNA by utilizing near UV/blue light. The cyclobutane pyrimidine dimer (CPD)-PHR from Escherichia coli binds flavin adenine dinucleotide (FAD) as a cofactor and 5,10-methenyltetrahydrofolate (MTHF) as a light harvesting pigment, and specifically repairs CPD ...
Sun Ya-Guang - - 2013
Four metal complexes [Pd(L(1))Cl(2)·2H(2)O] (), [Pt(L(1))Cl(2)·2H(2)O] (), [Pd(L(2))Cl(2)·H(2)O] () and [Pt(L(2))Cl(2)·H(2)O] () (L(1) = 2,2'-bipyridyl-5,5'-dicarboxylic acid, L(2) = 2,2'-bipyridyl-4,4'-dicarboxylic acid) have been synthesized under hydrothermal conditions and fully characterized by IR and (1)H-NMR spectra, elemental analysis, and X-ray single crystal diffraction analysis. Interactions of these complexes with fish sperm DNA ...
Yücel A - - 2013
Behçet's disease (BD) is a chronic immune-mediated systemic disease, characterized by oral and genital lesions and ocular inflammation. Several cytokine genes may play crucial roles in host susceptibility to BD, because the cytokine production capacity varies among individuals and depends on the cytokine gene polymorphisms. The association of the interleukin ...
Shiroff Adam M - - 2013
Introduction Tissue transplantation is an important adjunct to modern medical care and is used daily to save or improve patient lives. Tissue allografts include bone, tendon, corneas, heart valves and others. Increasing utilization may lead to tissue shortages, and tissue procurement organizations continue to explore ways to expand the cadaveric ...
Grover Manita - - 2013
PURPOSE: The aim of this study was to assess the use of single implant-supported, magnet-retained mandibular overdentures to improve the oral health-related quality of life (OHRQoL) and masticatory performance of patients wearing conventional complete dentures. The study also aimed at comparing the OHRQoL, masticatory performance, and crestal bone loss with ...
Masumo Ray - - 2013
Abstract Objective. To assess the reproducibility of caregivers' responses to dietary recall from birth and 24-h dietary recall with respect to infants' intake of sugared snacks and to assess whether those assessment methods provide comparable results for groups of infants. Re-test reliability and clinical covariates of time to first exposure ...
La Frano Michael R - - 2013
Biofortification of cassava with the provitamin A carotenoid β-carotene is a potential mechanism for alleviating vitamin A deficiency. Cassava is a staple food in the African diet, but data regarding the human bioavailability of β-carotene from this food are scarce. The objective of the present study was to evaluate provitamin ...
Ruddle Jonathan B - - 2013
BACKGROUND: To determine the incidence and predictors of glaucoma following surgery for congenital and infantile cataract in an Australian population DESIGN: Retrospective cohort study PARTICIPANTS: Infants (age <12 months) during lens extraction between January 1992 and May 2006, from two tertiary referral centres METHODS: Children with uveitis, anterior segment dysgenesis, ...
Kisch A - - 2013
The first international recommendations and guidelines for the care of sibling stem cell donors were established in 2010, and have not yet been evaluated. However, a model for information and care of adult potential sibling stem cell donors (the IC model) developed and introduced at the Skåne University Hospital, Lund, ...
Lee Namheon - - 2013
OBJECTIVE: With the success of early repair, continued functional assessment of repaired congenital heart disease is critical for improved long-term outcome. Pulmonary regurgitation, which is one of the main postoperative sequelae of congenital heart disease involved with the right ventricle (RV) such as tetralogy of Fallot and transposition of the ...
Chereddy Narendra Reddy - - 2013
A highly selective and efficient single molecular FRET based sensor has been developed for the ratiometric detection of Fe(3+) in aqueous samples and live cells.
Thomson William Murray - - 2013
OBJECTIVE: To develop short-form versions of the Parental-Caregivers Perceptions Questionnaire (P-CPQ) and Family Impact Scale (FIS). METHODS: Pretest/post-test clinical studies involved parent-completed questionnaires (the P-CPQ and the FIS) before and some weeks after dental care (under general anaesthesia) for early childhood caries (ECCs) in consecutive clinical samples from Wellington and ...
Mironava Tatsiana - - 2013
Abstract Gold nanoparticles (AuNPs) are used in various fields; however, their potential health risk(s) are still under the question. In this manuscript, we describe the interactions of AuNPs with human adipose derived stromal cells (ADSCs) and show that they are able to penetrate cell membrane and are stored in vacuoles. ...
Do T-V - - 2013
Aurora kinase A (AURKA) localizes to centrosomes and mitotic spindles where it mediates mitotic progression and chromosomal stability. Overexpression of AURKA is common in cancer, resulting in acquisition of alternate non-mitotic functions. In the current study, we identified a novel role for AURKA in regulating ovarian cancer cell dissemination and ...
Sheppard D - - 2013
The impact of donor-recipient ABO incompatibility on long-term BMT outcomes remains controversial. A common strategy is to deplete the donor marrow of red cells, although this variably reduces the number of CD34+ cells. This 10-year retrospective study assessed the impact of recipient plasma exchange in major ABO-incompatible allogeneic BMT on ...
Martin Kevan A C - - 2013
In common with other areas of the prefrontal cortex, activity in frontopolar area 10 is probably modulated by dopamine. We studied the dopaminergic innervation of monkey prefrontal area 10 by immunostaining with tyrosine hydroxylase (TH) antibodies. TH-positive axons in layer 3 were examined by electron microscopy of series of ultrathin ...
Gakis Georgios - - 2013
Abstract This reviews describes the concept of androgen-dependent growth of bladder cancer and the role of single-nucleotide polymorphisms (SNPs) located on chromosome 8q24 as a common carcinogenetic pathway for the development of concomitant prostate and bladder cancer. Recent genome-wide association studies have identified high-risk SNPs on chromosome 8q24 that have ...
D'Assoro A B AB 1] Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN, USA [2] Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN, - - 2014
In this study, we demonstrate that constitutive activation of Raf-1 oncogenic signaling induces stabilization and accumulation of Aurora-A mitotic kinase that ultimately drives the transition from an epithelial to a highly invasive mesenchymal phenotype in estrogen receptor α-positive (ERα(+)) breast cancer cells. The transition from an epithelial- to a mesenchymal-like ...
van der Velden W J F M WJ Department of Hematology, Radboud University Nijmegen Medical Center, Nijmegen, The - - 2013
Gastrointestinal (GI) mucositis is a common side effect of intense chemotherapy to prepare patients for hematopoietic SCT. Measuring intestinal damage objectively remains difficult, and clinicians often rely on albumin levels as an indicator of GI mucositis, but citrulline might be a more specific marker, which has in the past been ...
Reynaud Olivier - - 2013
Measurements of tumor microvasculature are important to obtain an understanding of tumor angiogenesis and for the evaluation of therapies. In this work, we characterize the evolution of the microvascular flux at different stages of tumor growth in the 9L rat brain tumor model. The absolute quantification of cerebral blood flux ...
Laux Daniela - - 2013
OBJECTIVE: The objective was to report two new patients with the diagnosis of alveolar capillary dysplasia and congenital heart disease, to describe the associated cardiac defects seen in these cases and in the literature, and to consider recent genetic advances concerning the FOX transcription factor gene cluster in chromosome 16q24.1q24.2. ...
Cabán-Acevedo Miguel - - 2013
We report the growth, structural and electrical characterization of single-crystalline iron pyrite (FeS2) nanorods, nanobelts and nanoplates synthesized via sulfidation reaction with iron dichloride (FeCl2) and iron dibromide (FeBr2). The as-synthesized products were confirmed to be single-crystal phase pure cubic iron pyrite using powder X-ray diffraction, Raman spectroscopy, and transmission ...
Ackerman Josh T - - 2013
Bird eggs are commonly used in mercury monitoring programs to assess methylmercury contamination and toxicity to birds. However, only 6% of >200 studies investigating mercury in bird eggs have actually measured methylmercury concentrations in eggs. Instead, studies typically measure total mercury in eggs (both organic and inorganic forms of mercury), ...
Wilson S - - 2013
The family support needs of parents with an intellectual disability (ID) are relatively unknown. This paper reviewed two types of intervention for parents with ID: those designed to strengthen social relationships and those teaching parenting skills. A literature search was conducted using electronic databases and a limited number of evaluative ...
Thomas Merlin C - - 2013
The need for new approaches to manage the increasing numbers of patients with diabetes and their burden of complications is urgent. Of these, chronic kidney disease imposes some of the highest costs, both in dollars and in terms of human suffering. In individuals with diabetes, the presence and severity of ...
D'souza Melroy A - - 2013
Abstract Background. Intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) is a rare but increasingly diagnosed clinical entity. Typical cholangioscopic findings usually include intraductal protruding papillary tumors that secrete mucus. Methods. Clinical, radiological and histopathological data of seven consecutive patients who were found to have IPMN-B were analyzed. Results. ...
Walton James W - - 2013
The synthesis, structure and photophysical properties of a series of highly emissive europium complexes is reported. Certain complexes enter mammalian cells by macropinocytosis and stain the mitochondria selectively, allowing observation of the Eu emission in cellulo by time-gated spectral imaging.
Dennis Maureen - - 2013
Social communication involves influencing what other people think and feel about themselves. We use the term conative theory of mind (ToM) to refer to communicative interactions involving one person trying to influence the mental and emotional state of another, paradigmatic examples of which are irony and empathy. This study reports ...
Towle Kaitlyn M - - 2013
The tricyclic peptides neopetrosiamides A and B, isolated from the marine sponge Neopetrosia sp., are potential antimetastatic agents that inhibit tumour cell invasion by both amoeboid and mesenchymal migration pathways. They differ in the stereochemistry of the methionine sulfoxide at position 24. Our previously reported syntheses using an orthogonal sulfur ...
Ezzalfani Monia - - 2013
The aim of a phase I oncology trial is to identify a dose with an acceptable safety profile. Most phase I designs use the dose-limiting toxicity, a binary endpoint, to assess the unacceptable level of toxicity. The dose-limiting toxicity might be incomplete for investigating molecularly targeted therapies as much useful ...
Del Campo Lara - - 2013
Increasing evidence shows that sex hormones exert a protective effect on the vasculature, especially in the regulation of the active vasomotor responses. However, whether sex hormones affect vascular remodeling is currently unclear. In the present study, we tested the hypothesis that testosterone in males and β-estradiol in females prevent inward ...
Kumar S M SM Departments of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, - - 2014
Adult stem cells are multipotent and persist in small numbers in adult tissues throughout the lifespan of an organism. Unlike differentiated cells, adult stem cells are intrinsically resistant to senescence. It is unclear how adult stem cells in solid organs respond to oncogenic stimulation and whether these cells have a ...
Lazarides Theodore - - 2013
Several recent studies have shown that the combination of photosensitizers with metalloenzymes can support a light-driven multi-electron reduction of molecules such as CO2 or HCN. Here we show that the association of the Zn tetramethyl pyridinium porphyrin (ZnTMPyP4+) photosensitizer with the multi-copper oxidase laccase allows to link the oxidation of ...
Huang Haowen - - 2013
In this paper, A label-free multiplex plasmonic sensor has been developed to selectively determine different metal ions including Fe3+, Hg2+, Cu2+ and Ag+ ions based on single type of gold nanorod (GNR). Under proper conditions, these metal ions can react with GNRs, resulting in changes of nanostructure and composition. The ...
Yıldız H - - 2013
We investigated short (6 months) and long (12 months) term inhibitory effects of low (200 ppm) and high (400 ppm) dosages of acetylsalicylic acid (aspirin) on exocrine pancreatic carcinogenesis. It is known that exocrine pancreatic carcinogenesis can be detected by the presence of atypical acinar cell foci (AACF) in pancreas. ...
Yu Bo-lan BL Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institute, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China. - - 2013
Benzothiophene compounds are selective estrogen receptor modulators (SERMs), which are recently found to activate antioxidant signaling. In this study the molecular mechanisms of antioxidant signaling activation by benzothiophene compound BC-1 were investigated. HepG2 cells were stably transfected with antioxidant response element (ARE)-luciferase reporter (HepG2-ARE cells). The expression of nuclear factor ...
Zhang Yi Y Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi'an, Shaanxi, - - 2013
Prader-Willi syndrome (PWS) is a genetic imprinting disorder characterized mainly by hyperphagia and early childhood obesity. Previous functional neuroimaging studies used visual stimuli to examine abnormal activities in the eating-related neural circuitry of patients with PWS. It was found that patients with PWS exhibited both excessive hunger and hyperphagia consistently, ...
Minderhoud Janna - - 2013
Despite many global initiatives to eliminate avoidable blindness, the number of cataract-blind people is still unacceptably high in many parts of the world, particularly in remote rural areas of developing countries. One of the established ways to increase uptake of cataract services is by extending ophthalmic care facilities to rural ...
Lee Paul H - - 2013
OBJECTIVE: To assess the association between self-reported oral health (SROH) and general health, this study examined the cross-sectional associations between SROH and nine chronic health conditions, namely cancer, diabetes, high blood pressure, high cholesterol, thyroid disease, nervous system disease, eye/nose/throat disease, stomach/intestinal disease, and musculoskeletal disease in Hong Kong. METHODS: ...
Pendergast Julie S JS Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA. - - 2013
The organisation of timing in mammalian circadian clocks optimally coordinates behavior and physiology with daily environmental cycles. Chronic consumption of a high-fat diet alters circadian rhythms, but the acute effects on circadian organisation are unknown. To investigate the proximate effects of a high-fat diet on circadian physiology, we examined the ...
Bolic Vedrana - - 2013
Abstract Aim: The aim of this study was to investigate computer use in educational activities by students with attention deficit hyperactivity disorder (ADHD) in comparison with that of students with physical disabilities and students from the general population. Methods: The design of the study was cross-sectional with group comparison. Students ...
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