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Results 201 - 250 of 4799
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He Jiao-Jiang - - 2013
ABSTRACT: Focal cortical dysplasias (FCDs) are increasingly recognized as important causes of medically intractable epilepsy. To understand the potential role of the interleukin 17 (IL-17) system in the epileptogenesis of FCDs, we studied the expression patterns of the IL-17 system in 15 FCD type Ia (FCDIa), 12 FCD type IIa ...
Li Philip Kam-Tao - - 2013
The treatment of immunoglobulin A (IgA) nephropathy with normal renal function and minimal proteinuria is unknown. We randomly assigned 60 patients with IgA nephropathy, proteinuria <0.5 g/day, normal blood pressure and renal function to ramipril 2.5 mg daily or no treatment. Patients were followed for 5 years for the development ...
Fosse Pacôme - - 2013
ABSTRACT: Hepatic adenoma is a rare, benign tumor (with potential for malignant degeneration) and its diagnosis is difficult because its presentation is highly variable in medical imaging, particularly with MRI. In such cases, the use of a hepatic biopsy is usually recommended. FDG-PET/CT provides a very significant predictive value for ...
Willits Kathryn A - - 2013
Children with special healthcare needs (CSHCN) tend to miss more school because of illness. Medical homes are a model of primary health care that coordinate services to better meet the needs of the child. The purpose of this study was to examine the association between presence of medical home and ...
Dreborg Sten - - 2013
A Working Group on Pediatric Allergology was formed in 1984, which rapidly developed to become the European Society on Pediatric Allergology and Clinical Immunology (ESPACI) in 1988 with its own journal, Pediatric Allergology and Immunology. ESPACI worked together with the European Academy of Allergology and Clinical Immunology (EAACI) to form ...
Ojo Joseph-Olubunmi - - 2013
ABSTRACT: Extensive tau-immunoreactive neurons and glial cells associated with chronic traumatic encephalopathy (CTE) have been documented in the brains of some professional athletes and others with a history of repetitive mild traumatic brain injury (r-mTBI). The neuropathology and tau involvement in mTBI have not been extensively studied in animal models, ...
Eisenberg Burton L - - 2013
Although adjuvant imatinib (IM) for high risk GIST is an accepted treatment consideration, the duration of therapy remains controversial. The recently published SSGXVIII/AIO randomized clinical trial of 3 years vs. 1 year of adjuvant IM has established a benefit of RFS and OS for the 3 year cohort. Future studies ...
Vlenterie Myrella - - 2013
Neurofibromatosis I may rarely predispose to pheochromocytoma and gastrointestinal stromal tumors. A 59-year-old woman with neurofibromatosis I presented with pheochromocytoma of the left adrenal gland. During surgery, 3 gastrointestinal stromal tumors adjacent to the stomach and small intestine were removed. Despite appropriate thrombosis prophylaxis, the patient died of a pulmonary ...
Maneechotesuwan K - - 2013
Plasticity of CD4(+) lymphocyte Th17/regulatory T cell (Treg) subsets is involved in the pathogenesis of chronic airway inflammatory diseases, such as asthma. Reversal of Th17/Treg cell balance towards Treg cells may be beneficial for the suppression of chronic Th2 cell-mediated inflammatory diseases, such as asthma. However, the effect of the ...
Li Rong Cheng - - 2013
: Vaccines against hepatitis A provide long-lasting protection in both adults and children. The aim of this study was to demonstrate that the inactivated hepatitis A vaccine AVAXIM 80U Pediatric is safe and not inferior in terms of seroprotection rate to HAVRIX 720 vaccine 1 month after booster vaccination. : ...
Ebo D G - - 2013
Wasp venom allergy is a potentially life-threatening condition with serious consequences of diagnostic error. To assess whether component-resolved diagnosis, using non-glycosylated recombinant allergen components from yellow jacket can add to the diagnosis of wasp venom allergy. In total, 148 patients with a wasp (yellow jacket) allergy were included, 91 with ...
Weese J Scott - - 2013
The skin harbours a diverse and abundant, yet inadequately investigated, microbial population. The population is believed to play an important role in both the pathophysiology and the prevention of disease, through a variety of poorly explored mechanisms. Early studies of the skin microbiota in dogs and cats reported a minimally ...
Wang L - - 2013
The novel HLA-A*24:128 shows one nucleotide change from HLA-A*24:02:01:01 in exon 2 at position 155 from A to G.
Brachelente Chiara - - 2013
Background -  Although cutaneous stem cells have been implicated in skin tumourigenesis in humans, no studies have been conducted to elucidate the presence and the possible role of stem cells in hair follicle tumours in the dog. Hypothesis -  Stem cell markers are expressed in canine epidermal and follicular tumours and can ...
Cruz Ruy J RJ - - 2013
Liver transplantation (LTx) for hepatoblatoma appears to be increasing. Favorable tumor histology is increasingly linked to survival after surgical resection and could also determine posttransplantation outcomes. To evaluate national trends in tumor and LTx incidence as the basis for observations at some LTx centers, and determinants of survival after LTx ...
Venkataram Aniketh - - 2013
An 18-year-old phenotypic male presented with an irreducible left inguinal mass, gynecomastia, and hypospadias. This mass on exploration was found to be a nonfunctional uterus with ipsilateral ovary and was excised. Further investigation confirmed the presence of a contralateral testis and a genotype of 46, XX. This confirmed the diagnosis ...
Cristancho Sayra M - - 2013
Surgery is an environment in which being an expert requires the ability to manage the unexpected. This feature has necessitated a shift in surgical decision-making research. The present study explores the processes by which surgeons assess and respond to nonroutine challenges in the operating room. We used a grounded theory ...
Del Conde Ian - - 2013
Although anticoagulation therapy markedly reduces the risk of stroke in patients with atrial fibrillation, up to 50% of these patients are deemed ineligible for anticoagulation. In this manuscript we provide a framework to assess the net clinical benefit of anticoagulation in patients with atrial fibrillation with an increased risk of ...
Prieto Elena - - 2013
Accuracy in the quantification of the SUV is a critical point in PET because proper quantification of tumor uptake is essential for therapy monitoring and prognosis evaluation. Recent advances such as time-of-flight (TOF) and point-spread-function (PSF) reconstructions have dramatically improved detectability. However, first experiences with these techniques have shown a ...
Sasikumar Arun - - 2013
ABSTRACT: Metastatic tumors of the penis are rare, with priapism as the predominant symptom in a significant number of cases. The genitourinary tract and rectum are the most common primary sites. FDG PET/CT has established role in detection of distant metastasis in various malignancies. The authors describe a case of ...
Zharkova Maria S - - 2013
Cytochromes P450 comprise a large superfamily and several of their isoforms play a crucial role in metabolism of xenobiotics, including drugs. Although these enzymes demonstrate broad and cross-substrate specificity, different cytochrome P450 subfamilies exhibit certain selectivity for some types of substrates. Analysis of amino acid residues of the active sites ...
Innerå Marie - - 2013
Background -  Pituitary pars intermedia dysfunction (PPID) in older equids is commonly recognized by a long hair coat that fails to shed. Objective -  The aim of this study was to compare hair follicle stages in PPID-affected horses with excessively long hair coats with the stages of normal aged horses (controls) and ...
Rush Kathy L - - 2013
The purpose of this study was to understand older adults' perspectives of strength in their daily lives. Maintaining strength is important as the population ages and many older adults live into their 80s and 90s. Few studies have explored older adults' views of strength and its management as they age. ...
Wu Bing - - 2013
ABSTRACT: A 71-year-old man presented with a progressive right knee pain which persisted for 6 months and was not relieved by pain medications. He had a history of lung squamous carcinoma 1 year ago. X-ray and magnetic resonance imaging (MRI) revealed hyperostosis, degenerative changes, and occupancy lesions of the right ...
Luger Michiel H A - - 2013
To evaluate the influence of patient age on the postoperative outcomes in eyes with myopia higher than 5.00 diopters (D) that had laser in situ keratomileusis using the Schwind Amaris laser system. Private practice, Utrecht, The Netherlands. Case series. At the 1-year follow-up, right eyes with preoperative myopia higher than ...
Shapiro Ralph S - - 2013
Subcutaneous immunoglobulin (SCIG) therapy is gaining favor for the management of primary immunodeficiency disease (PIDD) in adults and children. A retrospective chart review captured data on 96 pediatric patients with PIDD using SCIG (16% or 20%) delivered by infusion pump or SC rapid push over 620 clinic visits. Patients previously ...
Yuan Jie - - 2013
Lu-labeled ethylenediamine-N,N,N',N'-tetrakis methylene phosphonic acid (Lu-EDTMP), was used to palliate metastatic bone pain as a new bone-seeking radiopharmaceutical. In this phase II study, we assessed the efficacy and safety of Lu-EDTMP for bone pain palliation in patients with breast cancer and hormone refractory prostate cancer with bone metastases. Sixteen patients ...
Imperiale Alessio - - 2013
ABSTRACT: The understanding of radiotracer's physiological biodistribution as well as the potential source of false-positive results is crucial for an accurate diagnostic interpretation of F-fluorocholine PET/CT examination in patients with prostate cancer. We illustrate the results of whole-body F-fluorocholine PET/CT in a 79-year-old man with biochemical suspicion of prostate adenocarcinoma ...
Saha Ranajay - - 2013
In this contribution, we study the effect of confinement on the ultrafast electron transfer (ET) dynamics of riboflavin binding protein (RBP) to the bound cofactor riboflavin (Rf, vitamin B2), an important metabolic process, in anionic sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles (AOT-RMs) of various hydration levels. Notably, in addition to excluded ...
Liu Shuai - - 2013
ABSTRACT: A 31-year-old female patient with papillary thyroid cancer, status post-total thyroidectomy and radioablation with I underwent posttherapy whole-body scan with SPECT, which revealed increased iodine activity in the cervix. The subsequent ultrasound examination demonstrated that the site of elevated iodine activity was caused by cervical Nabothian cyst.
Proclemer Alessandro - - 2013
The purpose of the EP wire is to examine the clinical practice in the management of sustained ventricular tachycardia (VT), with special focus on diagnostic and therapeutic strategies. Forty-five European centres, all members of the EHRA-EP Research network completed the questions of the survey. There was an equal distribution of ...
Gerbal-Chaloin Sabine - - 2013
Inflammation and infection have long been known to affect the activity and expression of enzymes involved in hepatic and extrahepatic drug clearance. Significant advances have been made to elucidate the molecular mechanisms underlying the complex cross-talk between inflammation and drug-metabolism alterations. The emergent role of ligand-activated transcriptional regulators, belonging to ...
Guida Michele - - 2013
Ovarian dysgerminoma is a rare tumor that affects adolescent girls and young women. Due to its high radio-chemosensitivity, prognosis is normally excellent. Relapses occur in less than 20% of early stage disease, but are more frequent in advanced disease. It is known that some benign mediastinal processes may mimic tumor ...
Khubchandani Jagdish - - 2013
This study assessed the perceptions and practices of school nurses regarding adolescent dating violence (ADV). The membership list of the National Association of School Nurses was used to identify a national random cross-sectional sample of high school nurses in the United States (N = 750). A valid and reliable survey instrument was ...
Elias Joseph Abraham - - 2013
The aim of this study was to assess amputee care-related educational offerings and barriers to further educational opportunities in United States physical medicine and rehabilitation residency programs. A two-part survey was distributed to all United States physical medicine and rehabilitation residency program directors. Part 1 assessed the use of educational ...
Hayes Kim A - - 2013
There has been little evaluation of school-located vaccination programs that offer human papillomavirus (HPV) vaccine in US schools without health centers (ie, extramural programs). This article summarizes lessons learned from such programs. In July to August 2010, 5 programs were identified. Semistructured, in-depth telephone interviews were conducted with program representatives ...
Pahud Barbara A - - 2013
BACKGROUND:: Monovalent 2009 H1N1 influenza vaccines were licensed and administered in the United States during the H1N1 influenza pandemic between 2009 and 2013. METHODS:: Vaccine Adverse Event Reporting System received reports of adverse events following immunization (AEFI) after H1N1 vaccination. Selected reports were referred to the Centers for Disease Control ...
Kanda Satoko - - 2013
Background -  Filaggrin (FLG) is a key protein for skin barrier formation and hydration of the stratum corneum. In humans, a strong association between FLG gene mutations and atopic dermatitis has been reported. Although similar pathogenesis and clinical manifestation have been argued in canine atopic dermatitis, our understanding of canine FLG ...
Kucukevcilioglu Murat - - 2013
We report ultrasound biomicroscopy (UBM) evaluation of a paintball-related traumatic cataract with a posterior capsule tear. Slitlamp examination revealed anterior and posterior subcapsular cataracts with a suspicious tiny posterior capsule tear within the larger area of posterior bulging. Ultrasound biomicroscopy (35 MHz) confirmed the presence of a sub-1.0 mm posterior ...
Mohammadpour Mehrdad - - 2013
We report the case of a 52-year-old woman who developed bilateral anterior and posterior subcapsular cataracts with anterior capsule fibrosis 12 years after exposure to intensive radiation therapy. The woman had uneventful cataract surgery and gained 20/20 corrected distance visual acuity in both eyes. Hematoxylin-eosin staining of the anterior capsule ...
Moisseiev Elad - - 2013
An 86-year-old patient developed a significant intraocular inflammatory reaction after having phacoemulsification. Topical therapy did not eliminate the inflammation, and tissue plasminogen activator (tPA) was injected into the anterior chamber. A white corneal plaque appeared in the previously clear cornea within days of the injection. The lesion was diagnosed as ...
Burt Leah - - 2013
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. It's estimated that more than 13 million U.S. adults have COPD, and as many as 24 million have evidence of impaired lung function, suggesting that COPD is underdiagnosed. Even when patients receive optimal COPD ...
Olson Jeffrey L - - 2013
Spontaneous late subluxation of an intraocular lens (IOL) is a rare but serious complication of cataract surgery, often associated with poor zonular support. The management of this complication with a conventional forceps is difficult because the forceps often cannot adequately grasp the optic or haptic to fixate the IOL to ...
de Vries Niels E - - 2013
This literature review looks at the current status of multifocal intraocular lenses (IOLs) in cataract surgery. The results of implantation of multifocal IOLs of diffractive, refractive, and hybrid diffractive-refractive design are described with regard to uncorrected near and distance visual acuity and spectacle independence. The occurrence of photic phenomena and ...
Yeu Elizabeth - - 2013
A 43-question survey was e-mailed to all resident members of the American Society of Cataract and Refractive Surgery (ASCRS), ASCRS members in practice for 5 or fewer years, and residency program directors of 118 U.S. Accreditation Council for Graduate Medical Education-accredited ophthalmology programs (for distribution to their residents) in June ...
Afshar Maryam - - 2013
Antimicrobial peptides (AMPs) have a pivotal role in cutaneous innate immunity. They are present in the skin of many animals, including mammals, and are both constitutively present and inducible by infection and injury. Antimicrobial peptides exhibit antimicrobial activity against bacteria, viruses, fungi and parasites, with different potencies depending on their ...
Williams Hywel C - - 2013
This narrative review highlights areas within the epidemiology of human atopic dermatitis (AD) where significant progress has been made and where considerable ignorance still exists. The review is supported by systematic reviews wherever possible, with the purpose of stimulating fresh approaches to human and veterinary research into AD. Areas of ...
Harman Robert J - - 2013
Adult stem cells come from many sources and have the capacity to differentiate into many cell types, including those of the skin. The most commonly studied stem cells are those termed mesenchymal stem cells (MSCs), which are easily isolated from bone marrow and adipose tissue. Mesenchymal stem cells are known ...
Nishifuji Koji - - 2013
The stratum corneum (SC) is the outermost region of the epidermis and plays key roles in cutaneous barrier function in mammals. The SC is composed of 'bricks', represented by flattened, protein-enriched corneocytes, and 'mortar', represented by intercellular lipid-enriched layers. As a result of this 'bricks and mortar' structure, the SC ...
Salerno Jennifer - - 2013
This article describes a school-wide sexually transmitted infection (STI) screening to identify adolescent high-risk sexual behaviors, STI history/incidence, and presence of chlamydia and gonorrhea, and examines relationships between high-risk behaviors and screening positive for chlamydia and gonorrhea in an alternative high school setting. School-wide chlamydia and gonorrhea education and screening ...
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