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Tavassoli Setareh - - 2013
The production of highly efficient, recyclable and cost-effective enzymes is one of the most important goals in industrial biotechnology. Bacterial spores are highly resistant to harsh environmental conditions, easy to produce and are suitable for manipulation of genetic materials. These features make them a very efficient tool for biotechnology. Here, ...
Abuzenadah Adel M - - 2013
We describe in this report a case of a 6-years-old female who presented at the age of 1 month with a mucocutaneous bleeding and suspected thrombocytopenia. The patient's condition was refractory to the known idiopathic thrombocytopenic purpura treatments and congenital form of Thrombocytopenia was suspected following the delivery of a male ...
D'Amelio Patrizia - - 2013
We report the prevalence of osteoporosis, osteopenia, and fractures in a cohort of Italian women randomly recruited among the general population and validate the use of clinical guidelines in referring women for bone density testing. We enrolled in the study 995 healthy women (age range 45-92 years). A bone density test ...
Ferro Mark A - - 2013
PURPOSE: The present study investigated the higher-order summary factor structure of the Child Health Questionnaire Parent Form-50 (CHQ) in a sample of children with new-onset epilepsy. The secondary aim was to identify risk factors predicting health-related quality of life (HRQL) 24 months post-diagnosis. METHODS: Data came from the Health-related Quality of ...
Tufan Abdurrahman - - 2013
Enthesopathy is pathology of bony insertions of tendons, ligaments or joint capsules. It is a frequent finding in rheumatic diseases, like ankylosing spondylitis (AS) and Behçet's disease. Musculoskeletal complaints are common in patients with familial Mediterranean fever (FMF), and these could be a clinical manifestation of enthesopathy. Hence, we investigated ...
Neil Bateman - - 2013
BACKGROUND: Speech and language delay is a common developmental disorder. Persistent delay may lead to adverse effects on literacy, educational achievement and psychosocial development. Affected children are commonly referred to the Otolaryngologist, hence a structured management approach is required to facilitate diagnosis and allow for early intervention and improved outcomes. ...
Shen Bing - - 2013
Store-operated Ca(2+) entry (SOCE) is a common and ubiquitous mechanism regulating Ca(2+) influx into cells and participates in numerous biological processes including cell proliferation. Glomerular mesangial cells (GMCs) play a role in the regulation of the glomerular filtration rate. From a clinical point of view, many physiological functions alter with ...
Guo Tingting - - 2013
Three putative promoter regions were identified preceding the nisZ gene in Lactococcus lactis HSM-22. To investigate their function in the control of nisZ biosynthesis, green fluorescence protein (GFP) was adopted as probe to determine activities of the three promoters. The results showed that PnisZ-0 containing two sets of the -35 ...
Borges Vanessa - - 2013
Cohesion between sister chromatids, mediated by the chromosomal cohesin complex, is a prerequisite for their alignment on the spindle apparatus and segregation in mitosis. Budding yeast cohesin first associates with chromosomes in G1. Then, during DNA replication in S-phase, the replication fork-associated acetyltransferase Eco1 acetylates the cohesin subunit Smc3 to ...
Schrader Kevin K - - 2013
The Gram-negative bacterium Flavobacterium columunare is the cause of colmunaris disease in channel catfish (Ictalurus punctatus). In a previous study, the betaine-type alkaloid ungeremine, 1 obtained from Pancratium maritimum L. was found to have strong antibacterial activity against F. columnare. In this study, analogues of 1 were evaluated using a ...
Sekiya Takashi - - 2013
Regulatory T cells (T(reg) cells) develop from progenitor thymocytes after the engagement of T cell antigen receptors (TCRs) with high-affinity ligands, but the underlying molecular mechanisms are still unclear. Here we show that the Nr4a nuclear receptors, which are encoded by immediate-early genes upregulated by TCR stimulation in thymocytes, have ...
Hagan Donald L - - 2013
We conducted a greenhouse study to assess the effects of cogongrass (Imperata cylindrica) rhizochemicals on a suite of plants native to southeastern US pine savanna ecosystems. Our results indicated a possible allelopathic effect, although it varied by species. A ruderal grass (Andropogon arctatus) and ericaceous shrub (Lyonia ferruginea) were unaffected ...
Fernández-Rodríguez Santiago - - 2013
This study aims to determine the potential origin of Olea pollen recorded in Badajoz in the Southwest of the Iberian Peninsula during 2009-2011. This was achieved using a combination of daily average and diurnal (hourly) airborne Olea pollen counts recorded at Badajoz (south-western Spain) and Évora (south-eastern Portugal), an inventory ...
Hocqueloux Laurent - - 2013
OBJECTIVES: To characterize viro-immunological outcomes following long-term combined antiretroviral therapy (cART) initiated during primary HIV infection (PHI) or chronic HIV infection (CHI) and to identify factors predictive of optimal viro-immunological responder (OVIR) status. METHODS: This was a prospective, single-centre cohort study of HIV-1-infected patients on effective cART. Total cell-associated HIV ...
Weng Wei - - 2013
A one-step, eco-friendly ultrasound-assisted process is established for the rapid synthesis of sulfur-carbon composite cathode materials, avoiding the widely used, energy inefficient "melt-down" process for Li-S batteries. It is demonstrated that, without inserting sulfur into pores of carbon, the coulombic efficiency of SC/Li cell in the new DOL/D2 electrolyte is ...
Martínez-Villalba Anna - - 2013
Veterinary medicines are widely administered to farm animals since they keep animals healthy at overcrowded conditions. Nevertheless the continuous administration of medicines to farm animals can frequently lead to the presence of residues of veterinary drugs in consumption products. Amprolium is a quaternary ammonium compound used in the treatment of ...
Arısoy Ozden - - 2013
There is a high co-morbidity between chronic inflammatory disorders and depression. Proinflammatory cytokines like TNF-α seem to play a central role in the pathogenesis of these disorders, and its neutralization provides a potent treatment for inflammatory disorders. Few studies showed that TNF-α blockers also caused an improvement in depressive symptoms ...
Du Xueyu - - 2013
It is of both theoretical and practical importance to develop a universally applicable approach for the fractionation and sensitive lignin characterisation of Lignin-Carbohydrate Complexes (LCCs) from all types of lignocellulosic biomass, both natively and after different types of processing. In the present study, the previously reported fractionation approach that is ...
Montalbán Raúl - - 2013
BACKGROUND: To analyze and compare the relationship between anterior and posterior corneal shape evaluated by a tomographic system combining the Scheimpflug photography and Placido-disc in keratoconus and normal healthy eyes, as well as to evaluate its potential diagnostic value. METHODS: Comparative case series including a sample of 161 eyes of ...
Dzwigałowska A - - 2013
BACKGROUND/PURPOSE: One of the constantly developing fields in the area of cosmetology is the analysis of the efficacy of cosmetics products. Various instrumental techniques are available nowadays to evaluate changes in skin surface and measure anti-wrinkle activity. The aim of our study was to present and confront two methods of ...
Pillai Pramod P - - 2013
Regular arrays of nanorods having asymmetric cross-sections are fabricated by a combination of electrodeposition and glancing-angle deposition (GLAD). When these nanorods are embedded in a polymer matrix, they give rise to composite materials in which the structural anisotropy at the nanoscale translates into functional anisotropy in the form of direction-dependent ...
Schalek Petr - - 2013
Mucosal maxillary cysts (MMCs) are usually asymptomatic and are often diagnosed as an incidental finding. The aim of this study is to assess clinical significance of MMCs and the long-term effect of surgical treatment on the symptoms initially addressed to MMCs. The study included a retrospective analysis of 64 patients ...
Yu A - - 2013
Prostaglandin and prostamide analogues belong to a new substance group which came into the market in the 1990s. They have revolutionised antiglaucomatous therapy by their once-daily dosing regimen and fewer side effects. Today, prostaglandin and prostamide analogues are approved as first-line therapy for patients with primary open-angle glaucoma and ocular ...
Lagrow Alec P - - 2013
Branched metal nanostructures are of great technological importance because of their unique size- and shape-dependent properties. A kinetically controlled synthesis that uses polymorphism to produce branched nickel nanoparticles is presented. These nanoparticles consist of a face-centred cubic (fcc) core and extended arms of alternating fcc and hexagonal close-packed (hcp) nickel ...
Chaubey Nidhi - - 2013
We report the cloning, purification and cell proliferative activity of a novel recombinant GST tagged human granulocyte macrophage colony stimulating factor (GST-hGMCSF). The hGMCSF gene was PCR amplified from the cDNA of ACHN renal carcinoma cells and was cloned into the bacterial expression vector. The GST-hGMCSF was purified to homogeneity ...
Bernink Jochem H - - 2013
Innate lymphoid cells (ILCs) are effectors of innate immunity and regulators of tissue modeling. Recently identified ILC populations have a cytokine expression pattern that resembles that of the helper T cell subsets T(H)2, T(H)17 and T(H)22. Here we describe a distinct ILC subset similar to T(H)1 cells, which we call ...
van Harssel J J T - - 2013
Epilepsy and mental retardation limited to females (EFMR), caused by PCDH19 mutations, has a variable clinical expression that needs further exploration. Onset of epilepsy may be provoked by fever and can resemble Dravet syndrome. Furthermore, transmitting males have no seizures, but are reported to have rigid personalities suggesting possible autism ...
Vallot Céline - - 2013
X-chromosome inactivation (XCI) in mammals relies on XIST, a long noncoding transcript that coats and silences the X chromosome in cis. Here we report the discovery of a long noncoding RNA, XACT, that is expressed from and coats the active X chromosome specifically in human pluripotent cells. In the absence ...
Murugesan A G - - 2013
The effect of integrated textile mill effluent on the haematological characteristic of the fish Heteropneustes fossilis was studied. LC(50) values were found to be 34 %-38 % on 96-24 h duration. Four sub-lethal concentrations were selected for this study. Exposure to effluent caused an increase in large lymphocytes, monocytes, neutrophils and ...
Hoyt Brian S - - 2013
Cutaneous metastases occur in about 10% of patients with cancer, occasionally presenting as the initial sign of internal malignancy. Most often cutaneous metastases are an indicator of advanced cancer and are associated with a poor prognosis. The scrotum is a rare site of cutaneous metastasis, and metastatic tumor to the ...
Karalunas Sarah L - - 2013
Using Ratcliff's diffusion model and ex-Gaussian decomposition, we directly evaluate the role individual differences in reaction time (RT) distribution components play in the prediction of inhibitory control and working memory (WM) capacity in children with and without ADHD. Children with (n = 91, [Formula: see text] age = 10.2 years, 67 % male) and without ADHD ...
Hoch Matthias - - 2013
PURPOSE: To characterise further the previously observed cytochrome P450 3A4 (CYP3A4) interaction of the dual orexin receptor antagonist almorexant. METHODS: Pharmacokinetic interactions were investigated (n = 14 healthy male subjects in two treatment groups) between almorexant at steady-state when administered either concomitantly or 2 h after administration of single doses of simvastatin (40 mg) ...
Merritt Lucy - - 2013
Resting metabolic rates can vary greatly between individuals of the same species. These differences are generally repeatable and show moderate-to-high heritability, suggesting that they could be a target for natural selection. The present study therefore aimed to determine if inter-individual differences in resting metabolic rates (RMR) in garden skinks Lampropholis ...
Zhang De-Wen - - 2013
In this study, a simple miniaturized microliter electrochemical device was constructed using a disposable micropipette tip and a reproducible carbon fiber ultramicroelectrode. The novel electrochemical device set the electrochemical reaction in a micropipette tip containing an ultramicroelectrode. We investigated the feasibility of the designed electrochemical device by cyclic voltammetric measurements ...
Arora S - - 2013
Developmental processes require a precise spatio-temporal regulation of gene expression wherein a diverse set of transcription factors control the signalling pathways. MicroRNAs (miRNAs), a class of small non-coding RNA molecules have recently drawn attention for their prominent role in development and disease. These tiny sequences are essential for regulation of ...
Yin L - - 2013
AIMS: Increase the L-isoleucine production in Corynebacterium glutamicum by overexpressing the global regulator Lrp and the two-component export system BrnFE. METHODS AND RESULTS: The brnFE operon and the lrp gene were cloned into the shuttle vector pDXW-8 individually or in combination. The constructed plasmids were transformed into an L-isoleucine producing ...
Sheele Johnathan M - - 2013
OBJECTIVES: To determine whether the detection of human IgG bound to Schistosoma haematobium eggs from filtered urine could be used as a rapid diagnostic test (RDT-Sh). METHODS: We filtered 160 urine samples from children in the Kwale District of Kenya to isolate S. haematobium eggs and used anti-human IgG antibody conjugated ...
Kunisada Makoto - - 2013
UVA is currently thought to be carcinogenic because, similar to UVB, it induces the formation of cyclobutane pyrimidine dimers (CPDs). Various drugs have been reported to cause photosensitive drug eruptions as an adverse effect. Although the precise mechanism of photosensitive drug eruption remains to be elucidated, it is generally accepted ...
Ouyang Wei - - 2013
Dynamics of livestock and poultry manure nutrient was analyzed at a provincial scale from 2002 to 2008. The nutrient capacity of 18 kinds of croplands and grasslands to assimilate nutrients was assessed in the same temporal-spatial scale. Manure nitrogen (N) had increased from 5.111 to 6.228 million tons (MT), while ...
Jakobs S - - 2013
The aim of this article is the detailed consideration of the scientific opinion on the substantiation of health claims related to lutein and maintenance of vision, which was published by European Food Safety Authority (EFSA). The findings regarding the efficacy of lutein are important for the legal product classification. Thus, ...
Sun Min - - 2013
Uniformly cut In(2) O(3) truncated octahedrons are fabricated on a large scale by a simple chemical vapor deposition (CVD) technique. This theoretical analysis predicts that the emergence of {100} facets on the In(2) O(3) truncated octahedrons enhances oxygen evolution significantly in photocatalysis and experimental photoelectrochemical measurements are consistent.
Ghasemi Ebrahim - - 2013
In this study, changes in the chemical composition, pH, cell wall and degradability of ensiled rice straw were investigated when treated with alkali, acid, oxidant agents (1-11 %, w/w) and a combination of an oxidant with either an alkali (ALHP) or an acid (ACHP). The findings of the study revealed that ...
Kurimoto Etsuko - - 2013
ABSTRACT: BACKGROUND: Pulmonary emphysema is characterized by alveolar destruction and persistent inflammation of the airways. Although IL-17A contributes to many chronic inflammatory diseases, it's role in the inflammatory response of elastase-induced emphysema remains unclear. METHODS: In a model of elastase-induced pulmonary emphysema we examined the response of IL-17A-deficient mice, monitoring ...
Böhme Karola - - 2013
The present study aims to compare two molecular technologies, 16S rRNA sequencing and matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI TOF - MS), for bacterial species identification in seafood. With this aim, 70 reference strains from culture collections, including important seafood-borne pathogenic and spoilage bacterial species, and 50 strains ...
Zurhold Heike - - 2013
Despite the increasing research in gambling, the prevalence of problem gambling in the criminal justice population is rarely investigated, especially in Europe. Given the lack in knowledge the Hamburg study aimed at identifying the prevalence of problem gambling in the whole regional prison population. For this purpose two major approaches ...
Wong Russell - - 2013
Topical tacrolimus and pimecrolimus are indicated for the treatment of atopic dermatitis, but they have been studied in many off-label uses. We reviewed the English language literature to define their roles in treatment of vitiligo. Double-blind studies show that tacrolimus 0.1% ointment combined with excimer laser is superior to placebo, ...
Yang Ying - - 2013
Temperature and light intensity effects on biomass and lipid production were investigated in Ettlia oleoabundans to better understand some fundamental properties of this potentially useful but poorly studied microalgal species. E. oleoabundans entered dormant state at 5 °C, showed growth at 10 °C, and when exposed to light at 70 μmol photons per ...
Tsai Yuh-Shyan - - 2013
Gold nanoparticles (AuNPs) are widely used as carriers or therapeutic agents due to their great biocompatibility and unique physical properties. Transforming growth factor-beta 1 (TGF-β1), a member of the cysteine-knot structural superfamily, plays a pivotal role in many diseases and is known as an immunosuppressive agent that attenuates immune response ...
Drexler C - - 2013
A periodically driven system with spatial asymmetry can exhibit a directed motion facilitated by thermal or quantum fluctuations. This so-called ratchet effect has fascinating ramifications in engineering and natural sciences. Graphene is nominally a symmetric system. Driven by a periodic electric field, no directed electric current should flow. However, if ...
McGraw Gregory J - - 2013
Multicolor electrophosphorescent organic light-emitting diode (OLED) pixel patterning by organic vapor jet printing (OVJP) is demonstrated, showing that this technique is capable of rapidly generating high-definition full-color displays. The resolution limits, and means to achieve them are described using a combination of simulation and experimental approaches.
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