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Rabelo Sarita C - - 2013
Sugarcane bagasse was subjected to lime (calcium hydroxide) pretreatment and enzymatic hydrolysis for second-generation ethanol production. A central composite factorial design was performed to determine the best combination of pretreatment time, temperature, and lime loading, as well as to evaluate the influence of enzymatic loadings on hydrolysis conversion. The influence ...
Verma Harsha - - 2013
Porcine kobuvirus has been associated with piglet diarrhea in Asia and Europe, but there are no reports of its presence in the U.S. swine farms. We screened intestinal contents from 114 diarrheic pigs and fecal samples from 46 apparently healthy pigs to determine the presence of kobuvirus by reverse transcription-polymerase ...
de Klerk T A - - 2013
To determine whether primary trabeculectomies performed in a UK district general hospital, specifically without making use of mitomycin-C augmentation but with selective use of the low potency anti-metabolite 5-fluorouracil, produce an acceptable long-term intraocular pressure (IOP)-lowering effect for an unselected patient group. Retrospective analysis of the outcomes of all the ...
Nam Kwang-Mo - - 2013
Here we report development of the galvanostatic Fourier transform electrochemical impedance spectroscopy (FTEIS), which monitors impedance of electrochemical reactions activated by current steps. We first derive relevant relations for potential change upon application of a step current, obtain impedances theoretically from the relations by simulation, and verify them with experimental ...
Pifl Christian - - 2013
We recently found severe noradrenaline deficits throughout the thalamus of patients with Parkinson's disease (Pifl et al., 2012). Since this noradrenaline loss was especially severe in nuclei of the motor thalamus normally transmitting basal ganglia motor output to the cortex, we hypothesized that this noradrenaline loss aggravates the motor disorder ...
Lin Qing-Yuan - - 2013
The mechanical properties of ultra-thin membranes have attracted considerable attention recently. Nanoindentation based on atomic force microscope is commonly employed to study the mechanical properties. We find that the data processing procedures in previous studies are nice approximations, but they are difficult to illustrate the mechanical properties precisely. Accordingly, we ...
Hommer A - - 2013
A combination of antiglaucoma medications is indicated if monotherapy is not sufficient to achieve the predefined target pressure and/or in case of a progression of glaucomatous damage or conversion from ocular hypertension to glaucomatous optic neuropathy. Most recently many fixed combinations with two active compounds have become available for the ...
Hao Xinhong - - 2013
With the development of Internet, patients could enjoy health-care delivery services through telecare medicine information systems (TMIS) in their home. To control the access to remote medical servers' resources, many authentication schemes using smart cards have been proposed. However, the performance of these schemes is not satisfactory since modular exponential ...
Ponce Campos Guillermo E - - 2013
Climate change is predicted to increase both drought frequency and duration, and when coupled with substantial warming, will establish a new hydroclimatological model for many regions. Large-scale, warm droughts have recently occurred in North America, Africa, Europe, Amazonia and Australia, resulting in major effects on terrestrial ecosystems, carbon balance and ...
Chung-Davidson Yu-Wen - - 2013
ABSTRACT: BACKGROUND: Vertebrate pheromones are known to prime the endocrine system, especially the hypothalamic-pituitary-gonadal (HPG) axis. However, no known pheromone molecule has been shown to modulate directly the synthesis or release of gonadotropin releasing hormone (GnRH), the main regulator of the HPG axis. We selected sea lamprey (Petromyzon marinus) as ...
Mojtabai Ramin - - 2013
RATIONALE: Past research on the association of antidepressant medication use with glycemic control abnormalities has produced mixed results. OBJECTIVE: To examine the association of antidepressant use with glycemic control abnormalities and screen-positive diabetes in a representative population sample of US adults without a diagnosis of diabetes. METHODS: Using data from ...
Pasotti Fabio - - 2013
Abnormalities in plasma von Willebrand factor (vWF) concentration and function result in von Willebrand disease (vWD). The diagnosis requires a battery of tests such as screening procedures, confirmatory tests, phenotypic characterization and genotyping. The phenotypic testing (multimer pattern analysis) is important in order to subclassify the hereditary and the acquired ...
Jain Sachin Kumar Amruthlal - - 2013
BACKGROUND: Implantable cardioverter defibrillators (ICDs) have become an important part of the management of patients with congestive heart failure. At the time of ICD implantation, ventricular fibrillation (VF) is induced to assess adequate energy required for defibrillation. There are multiple parameters which influence the defibrillation safety margin (DSM); however, these ...
Schneider Stefan - - 2013
Assessing changes in brain activity under extreme conditions like weightlessness is a desirable, but difficult undertaking. Results from previous studies report specific changes in brain activity connected to an increase or decrease in gravity forces. Nevertheless, so far it remains unclear (1) whether this is connected to a redistribution of ...
Tokunaga Masao - - 2013
Halophilic β-lactamase (BLA) has been successfully used as a novel fusion partner for soluble expression of aggregation-prone foreign proteins in Escherichia coli cytoplasm (Appl Microbiol Biotechnol 86:649-658, 2010b). This halophilic BLA fusion technology was applied here for secretory expression in Brevibacillus. The "Brevibacillus in vivo cloning" method, recently developed by ...
Zhao Lei - - 2013
It has been reported that the imbalance of T helper IL-17-producing cells (Th17 cells)/regulatory T cells (Tregs) was closely associated with advanced tumor growth and poor prognosis in lung cancer, but little is known about whether this imbalance is existed in the peripheral blood of patients with non-small cell lung ...
Kilic Berna - - 2013
Background  Psoriasis is a chronic inflammatory disease affecting skin, nails, and joints. Although there are not many reports in the literature, ocular findings occur in approximately 10% of patients, in mostly those who have psoriatic arthritis. In this study, we aimed to evaluate eye involvement in psoriasis patients. Methods  This ...
Bakos Jan - - 2013
Aim of the present study was to evaluate effects of ligands of oxytocin receptors on gene expression of neurofilament proteins (nestin and microtubule-associated protein 2 (MAP2)) associated with neuronal differentiation and growth factors (brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF)) related to neuronal growth. Fluorescent staining of F-actin ...
Shrivastava Atul - - 2013
Miglitol, an anti-diabetic drug, has been shown to reduce plasma lipids and inhibit free radical generation. The anti-hyperlipidemic and antioxidant effects of miglitol were studied in triton-induced hyperlipidemic rats and high fat diet-fed obese rats. Plasma cholesterol and triglycerides levels were significantly lowered by miglitol at 100 mg/kg body weight doses. ...
Romero Rebecca M - - 2013
The common nitrogen mustard, mechlorethamine, can form a covalent crosslink between the two bases of a cytosine-cytosine mismatch pair within a DNA duplex. The crosslinked species can be readily separated from DNA monoadducts and unreacted strands using denaturing polyacrylamide gel electrophoresis (DPAGE). Here, using DNA 19mer duplexes that are mechlorethamine-crosslinked ...
Kahilogullari Gokmen - - 2013
PURPOSE: The arterial vascularization of the pineal gland (PG) remains a debatable subject. This study aims to provide detailed information about the arterial vascularization of the PG. METHODS: Thirty adult human brains were obtained from routine autopsies. Cerebral arteries were separately cannulated and injected with colored latex. The dissections were ...
Castagnini A - - 2013
OBJECTIVE: To investigate mortality and causes of death of short-lived psychotic disorders, by carrying out a comparison with bipolar disorder and schizophrenia. METHOD: Record linkage study to the official register of causes of death of all cases aged 15-64 years who were listed for the first time in the Danish Psychiatric ...
Mintern Justine D - - 2013
Dendritic cells (DCs) are an important target for vaccine delivery. It is shown that antibody functionalized polymer capsules can effectively target DCs; however, the internalization is highly dependent on the specific receptor targeted. This work highlights the importance of considering factors such as how the antibody/capsule is internalized, rather than ...
Leblanc A K - - 2013
We hypothesized that neutrophil function in tumour-bearing dogs is negatively impacted by chemotherapy. Flow cytometric techniques were used to assess neutrophil oxidative burst and phagocytic activities at baseline, 7 and 21 days after induction chemotherapy in 20 dogs with lymphoma. Dogs had a lower percentage of neutrophils exhibiting oxidative burst activity ...
Gallant Nancy R - - 2013
Appalachia is characterized by a high prevalence of individual-level risks for breast cancer, including physical inactivity and postmenopausal obesity. The availability of local, evidence-based programs to improve physical fitness is limited. We adapted an evidence-based intervention, StrongWomen, to improve physical fitness and increase breast cancer knowledge among women 40 years and ...
Wang Shao-Chen - - 2013
The polymorphic mutation frequencies for 154 Staphylococcus aureus isolates from Chinese bovine clinical mastitis cases were investigated. We found that nearly 29% of the isolates presented as weak mutators, while only two (1.3%) strong mutators were detected. Of the 15 weak mutators that exhibited ciprofloxacin resistance phenotypes, only one isolate ...
Agbohessi P T - - 2013
Acute toxicities of Tihan 175 O-TEQ, as well as its active ingredients flubendiamide and spirotetramat, and of Thionex 350 EC (active compound endosulfan) were measured for embryo-larval and juvenile stages of the African catfish Clarias gariepinus to assess risks of pesticide use in the cotton basin in Benin (West Africa). ...
Gao Qian - - 2013
BACKGROUND/PURPOSE: Changes in skin textures have been used to evaluate skin aging in many studies. In our previous study, we built some skin texture parameters, which can be used to evaluate skin aging of human dorsal hand. However, it will take too much time and need to work arduously to ...
Kortüm K - - 2013
Background: The importance and complexity of clinical trials is continuously increasing, especially in innovative specialties like ophthalmology. Therefore an efficient clinical trial site organisational structure is essential. In modern internet times, this can be accomplished by web-based applications.Methods: In total, 3 software applications (Vibe on Prem, Sharepoint and open source ...
Liu Zhanjun - - 2013
Increasing evidence has shown that antibiotics function as intermicrobial signaling molecules instead of killing weapons. However, mechanisms and key factors that are involved in such functions remain poorly understood. Earlier findings have associated antibiotic signaling with quorum sensing (QS); however, results varied among experiments, antibiotics, and bacterial strains. In this ...
Jo Youn Yi - - 2013
PURPOSE: The authors conducted a prospective, randomized, double-blind study to evaluate the anti-shivering efficacy of palonosetron for patients after gynecological laparoscopy under total intravenous propofol-remifentanil anesthesia. METHODS: Sixty female patients were randomly assigned to one of two groups and administered palonosetron 0.075 mg (palonosetron group, n = 30) or the same volume of ...
Rainey Helen - - 2013
BACKGROUND: Poor recognition of and response to acute illness in hospitalized patients continues to cause significant harm despite the implementation of safety strategies such as early warning scores. Patients and their relatives may be able to contribute to their own safety by speaking up about changes in condition, but little ...
Zaki Kamarul - - 2013
The introduction of targeted therapies, specifically those that target the VEGF receptor (VEGFR), PDGF receptor (PDGFR) and the mTOR pathways, has significantly changed the approach to patients with unresectable renal cell cancer (RCC). However, drug resistance develops through bypassing of targeted pathways. Regorafenib (BAY 73-4506) is a novel bi-aryl urea ...
Okada Masaho - - 2013
Definitive endovascular techniques have been developed for pacemaker lead extraction; however, a few patients require immediate secondary open heart surgery because of incomplete transvenous lead extraction. This study examined the safety, effectiveness, and long-term outcome of the removal of cardiovascular implantable electronic device (CIED) via median sternotomy under cardiopulmonary bypass. ...
Cheng Myra - - 2013
The aims of this study are twofold: (i) to pay tribute to Hartmann Stahelin for his scientific research on cyclosporin A; and (ii) to consider possible lessons for future pharmacological innovation by revisiting Stahelin's personal struggles to obtain fair recognition for his contribution to transplantation medicine.
Tsukahara Kazue - - 2013
BACKGROUND/AIMS: We studied annual, seasonal and gender-dependent changes in the intensity of facial wrinkles. METHODS: The study included 32 Japanese subjects (16 men, 16 women, aged 35-47). Wrinkles on the forehead, corner of the eye, lower eyelid and nasolabial groove of each subject were captured in photos and in replicas ...
Dijksterhuis Jan - - 2013
Growing hyphae of Rhizoctonia solani were stained with the endocytic marker dye FM4-64 and imaged by confocal microscopy. Staining of the plasma membrane was followed by labeling of organelles in the cytoplasm (after ~1 min) and of the Spitzenkörper (Spk; after ~2 min). Fluorescence recovery after photobleaching (FRAP) of the stained Spk ...
Wang Se - - 2013
Intramolecular and intermolecular hydrogen bonding in electronic excited states of calixarene building blocks bis(2-hydroxyphenyl)methane (2HDPM) monomer and hydrogen-bonded 2HDPM-H(2)O complex were studied theoretically using the time-dependent density functional theory (TDDFT). Twenty-four stable conformations (12 pairs of enantiomers) of 2HDPM monomer have been found in the ground state. From the calculation ...
Riansuwan Woramin - - 2013
Total proctocolectomy (TPC) with ileal pouch anal anastomosis (IPAA) is the standard treatment in classic familial adenomatous polyposis (FAP) patients [1]. Techniques of IPAA can be divided into two types; staple anastomosis with retained some rectal mucosa and endoanal mucosectomy with hand sewn anastomosis [2]. Endoanal mucosectomy is usually performed ...
Kuzucu Akin - - 2013
PURPOSES: The aim of this study was to assess the relationship between the pulmonary hydatid cyst size and the clinical presentation, surgical approach, and postoperative outcome. We review the problems encountered in treating large pulmonary hydatid cysts and highlight the risks associated with the rupture of the cyst and a ...
Saka Bayaki - - 2013
OBJECTIVE: The purpose of this study was to document the clinical profile, etiologies, and outcomes of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in hospitals in four sub-Saharan African countries. PATIENTS AND METHODS: A retrospective study on cases of SJS/TEN treated in dermatology departments and/or intensive care units in ...
Pastore Serena - - 2013
At least 30 % of children with chronic urticaria have an autoimmune aetiology with a positive autologous serum skin test (ASST). ASST is cheap, easy to perform and has good sensibility and specificity in detecting autoantibodies. In case of concern about reliability of ASST because of antihistamine medications, test transferability seems ...
Santos Danilo Oliveira - - 2013
The modification of MCM-41 was performed with 3-aminopropropyltrimethoxysilane. The structural order and textural properties of the synthesized materials were studied by X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimetry/differential thermogravimetry, nitrogen adsorption, and desorption analysis. The adsorption capacity of NH(2)-MCM-41 was studied with Remazol Red dye. The following parameters were studied ...
Blanpain Cédric - - 2013
Although many genes that lead to different types of cancer when mutated have been identified, the cells that initiate tumour formation following accumulation of these mutations have, until recently, remained elusive. This review explores how mouse genetic lineage-tracing experiments that allow the expression of oncogenes and/or the deletion of tumour ...
Guo L F - - 2013
PURPOSE: The presence of cerebral microbleeds (CMBs) may have predictive and diagnostic value for cerebrovascular diseases. The purpose of our study was to measure the phase values (PVs) of CMBs by phase maps. METHODS: We retrospectively analyzed 75 patients with hypertension who had CMBs using enhanced T2*-weighted angiography (ESWAN). The ...
Yolamanova Maral - - 2013
Inefficient gene transfer and low virion concentrations are common limitations of retroviral transduction. We and others have previously shown that peptides derived from human semen form amyloid fibrils that boost retroviral gene delivery by promoting virion attachment to the target cells. However, application of these natural fibril-forming peptides is limited ...
Demirel D - - 2013
D. Demirel, N. Akyürek and I. Ramzy Diagnostic and prognostic significance of image cytometric DNA ploidy measurement in cytological samples of cervical squamous intraepithelial lesions Objective:  To study the DNA ploidy pattern of uterine cervical squamous intraepithelial lesions (SILs) and its diagnostic and prognostic significance. Methods:  The study included 31 ...
Damodaran Omprakash - - 2013
The surgical microscope has revolutionized the practice of modern spine surgery. The major advantages of the microscope include better illumination, magnification and coaxial vision. It has also contributed to the welfare of the surgeon through improved ergonomics and opportunities to demonstrate surgical nuances to a training resident. However, there are ...
Lalande Laure - - 2013
Falls in geriatry are associated with important morbidity, mortality and high healthcare costs. Because of the large number of variables related to the risk of falling, determining patients at risk is a difficult challenge. The aim of this work was to validate a tool to detect patients with high risk ...
Gupta Nidhi - - 2013
Rapidly changing dietary practices accompanied by an increasingly sedentary lifestyle predispose to nutrition-related non-communicable diseases, including childhood obesity. Over the last 5 y, reports from several developing countries indicate prevalence rates of obesity (inclusive of overweight) >15 % in children and adolescents aged 5-19 y; Mexico 41.8 %, Brazil 22.1 %, India 22.0 % and Argentina ...
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