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Results 501 - 550 of 4815
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Pearn John H - - 2013
Botanical taxonomy is a repository of medical biographical information. Such botanical memorials include the names of some indigenous orchids of Australia. By searching reference texts and journals relating to Australian botany and Australian orchidology, as well as Australian and international medical and botanical biographical texts, I identified 30 orchids indigenous to ...
Ma Hai-rong HR Xinjiang Key Laboratory of Plant Resources and Natural Products Chemistry, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, - - 2013
Chickpea (Cicer arietinum L) is a traditional Uighur herb. In this study we investigated the estrogenic activities of the isoflavones extracted from chickpea sprouts (ICS) in ovariectomized rats. Ten-week-old virgin Sprague-Dawley female rats were ovariectomized (OVX). The rats were administered via intragastric gavage 3 different doses of ICS (20, 50, ...
Gordon L K LK Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, - - 2013
Understanding tumor-induced angiogenesis is a challenging problem with important consequences for the diagnosis and treatment of cancer. In this study, we define a novel function for epithelial membrane protein-2 (EMP2) in the control of angiogenesis. EMP2 functions as an oncogene in endometrial cancer, and its expression has been linked to ...
Tan Mei H - - 2013
Posterior staphyloma is a concave depression of the posterior shell of the eye globe that is frequently observed in highly myopic eyes. As hallmark lesion, it is seen in 90% of patients with high myopia and increases in prevalence with age.1 Highly myopic eyes with posterior staphylomata have a higher ...
Gigineishvili David - - 2013
A population-based cohort study was initiated in Georgia in March 2009 to collect epidemiologic data of malignant and non-malignant primary brain tumours. During the first year, 473 incident cases were identified. For a population of 4.3 million, the annual incidence rate was 10.25 per 100,000 inhabitants, age-standardized to the year ...
Sjöwall Christopher - - 2013
The pattern recognition molecules C-reactive protein (CRP) and C1q are of big interest in relation to the pathogenesis of systemic lupus erythematosus (SLE). Circulating autoantibodies against CRP and C1q are frequently found in SLE patients with active disease, particularly in lupus nephritis (LN), and rising levels reportedly relate to disease ...
Jiang Li - - 2013
Osteoarthritis (OA) is the most common form of arthritis, in which cartilage is irreversibly degraded, causing severe pain and disability. Current therapeutic strategies cannot repair damaged cartilage. We evaluated the repair potential of selected chondrogenic clonal MSCs (sC-MSCs) by delivering them into the injured cartilage site in a collagenase-induced OA ...
Liu Jun - - 2013
This study was performed to qualify goat fetal fibroblast (GFF) cell lines for genetic modification and somatic cell nuclear transfer (SCNT) to produce human lysozyme (hLYZ) transgenic goats. Nine GFF cell lines were established from different fetuses, and the proliferative lifespan and chromosomal stability were analyzed. The results suggested that ...
Heskamp Sandra - - 2013
Bevacizumab (anti-VEGF) and cetuximab (anti-EGFR) are approved antibodies for treatment of cancer. However, in advanced colorectal cancer, the combination fails to improve survival. As the reason for the lack of activity is unknown, this study aims to determine the effect of bevacizumab on targeting of anti-EGFR and IGF-1R antibodies in ...
Kalman Jonathan M - - 2013
Atrial fibrillation (AF) is estimated to affect 1%-2% of the population. It is increasing in prevalence and is associated with excess mortality, considerable morbidity and hospitalisations. AF is responsible for a significant and growing societal financial burden. Catheter ablation is an increasingly used therapeutic strategy for the management of AF; ...
Frank S A - - 2013
Three steps aid in the analysis of selection. First, describe phenotypes by their component causes. Components include genes, maternal effects, symbionts and any other predictors of phenotype that are of interest. Second, describe fitness by its component causes, such as an individual's phenotype, its neighbours' phenotypes, resource availability and so ...
Smolensky Koganov Elena - - 2013
Xanthorhodopsin (xR) is a retinal protein that contains, in addition to the retinal chromophore, a carotenoid (salinixanthin) which functions as a light-harvesting antenna (1). The center-center distance of the two polyene chains is 12-13 Å, but the distance between the two rings of the retinal and salinixanthin is surprisingly small ...
Seif A E - - 2013
Increasing treatment intensity has improved outcomes for children with neuroblastoma. We performed a pilot study in the Children's Oncology Group to assess the feasibility and toxicity of a tandem myeloablative regimen without TBI supported by autologous CD34-selected peripheral blood stem cells. Forty-one patients with high-risk neuroblastoma were enrolled; eight patients ...
Vandenbon Alexis - - 2013
ABSTRACT: BACKGROUND: Identification of cis- and trans-acting factors regulating gene expression remains an important problem in biology. Bioinformatics analyses of regulatory regions are hampered by several difficulties. One is that binding sites for regulatory proteins are often not significantly over-represented in the set of DNA sequences of interest, because of ...
Chan E W - - 2013
Lorcaserin is a new anti-obesity drug recently approved by US Food and Drug Administration. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the association of lorcaserin therapy with weight loss and adverse events in obese adults (18-65 years old). Weight loss of 3.23 kg (95% ...
Quail D F - - 2013
The progression of cancer from localized to invasive disease is requisite for metastasis, and is often characterized by epithelial-to-mesenchymal transition (EMT) and alterations in cellular adhesion and migration. Studies have shown that this transition is associated with an upregulation of embryonic stem cell-associated genes, resulting in a dedifferentiated phenotype and ...
Allen R S - - 2013
The purpose of this secondary data analysis was to characterize the Internet usage of rural veterans (n=201) who had either never enrolled, or had previously enrolled but not accessed, Veterans Affairs (VA) health services in at least 2 years. The VA Office of Rural Health (ORH)(ie part of the United ...
Polato Nicholas R - - 2013
Coral populations have declined worldwide largely due to increased sea surface temperatures. Recovery of coral populations depends in part upon larval recruitment. Many corals reproduce during the warmest time of year when further increases in temperature can lead to low fertilization rates of eggs and high larval mortality. Microarray experiments ...
Eckert Kerena A - - 2013
OBJECTIVE: The aim of this study was to examine changes in the prevalence of use of prescribed medicines in Australian community samples. STUDY DESIGN AND SETTING: In this study, face-to-face interviews were carried out with random, representative samples of South Australian adults, aged ≥15 years. Data on self-reported use of prescribed ...
Ogoh Shigehiko - - 2013
The respiratory chemoreflex is known to be modified during orthostatic stress though the underlying mechanisms remain to be established. To detremine the potential role of cerebral hypoperfusion, we examined the relationship between changes in middle cerebral artery mean blood velocity (MCA Vmean) and pulmonary ventilation (VE) from supine control to ...
Li Shuyi - - 2013
Litchi chinensis pericarp from litchi processing waste is an important plant source of A-type procyanidins, which were considered as a natural dietary supplement due to its high biological activity in vivo reported. Litchi pericarp oligomeric procyanidins (LPOPC) didn't selectively modify the growth of Streptococcus thermophilus and Lactobacillus casei-01 at concentrations ...
Shen C-J - - 2013
Only a few studies have investigated the use of PCT in the diagnosis of bone and joint infection, and these studies have had relatively small sample sizes. We performed a systematic review and meta-analysis of the diagnostic performance of serum procalcitonin (PCT) in the identification of osteomyelitis and septic arthritis ...
Yu De-gang DG Department of Orthopedics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200011, - - 2013
To investigate whether strontium ranelate (SR), a new antiosteoporotic agent, could attenuate cartilage degeneration and subchondral bone remodeling in osteoarthritis (OA). Medial meniscal tear (MMT) operation was performed in adult SD rats to induce OA. SR (625 or 1800 mg·kg(-1)·d(-1)) was administered via gavage for 3 or 6 weeks. After ...
Pushker Neelam - - 2013
Ectopic meningiomas within the orbit are very rare. Most of the previously reported cases were located along the medial wall. Here we report on three cases of ectopic meningiomas presenting as superomedial orbital masses along with their radiological and histopathological features. All three patients underwent surgical excision of the tumor ...
Instone Susan L - - 2013
The increasing number of Americans needing orthopedic health care is a growing concern given the aging population and the diminishing pool of primary and specialty care physicians. In a call to action, the Institute of Medicine's report, The Future of Nursing, advocates for innovative solutions, including the transformation of nursing ...
Keary Therese A - - 2013
Loring et al. (Journal of Clinical and Experimental Neuropsychology, 2005:27;610-617) observed relationships between VSVT hard item performance and IQ and memory indices in epilepsy surgical candidates, with a potential confound of low FSIQ on VSVT performance. The present study replicated the Loring et al. study in a larger sample and ...
Aldrigui Janaina Merli - - 2013
BACKGROUND: This study aimed to assess factors associated with occurrence of pulp necrosis (PN) in traumatized primary incisors, which may contribute to the prognosis of this outcome. DESIGN: Data were collected by single examiner through the analysis of clinical files of traumatized patients. The occurrence of PN in traumatized teeth ...
Kim Yong-Tae - - 2013
We report the original fabrication and performance of a photocurrent device that uses directly grown CdSe quantum dots (QDs) on a graphene basal plane. The direct junction between the QDs and graphene and the high quality of the graphene grown by chemical vapor deposition enables highly efficient electron transfer from ...
Galbally Megan - - 2013
OBJECTIVE: Our purpose was to determine if babies breastfed at 6 months of age were more likely to wake at night and less likely to sleep alone than formula-fed babies. PATIENTS AND METHODS: Data were drawn from the first wave of The Longitudinal Study of Australian Children, an ongoing, nationally ...
Turgut Adnan - - 2013
The aim of this study is to find the numbers of deaths by drowning incidents by using online search engines and online newspaper reports for all age groups covering five years (2007-2011) in Turkey, in order to conduct a population-based study for the first time in Turkey and to identify ...
Grytten Jostein - - 2013
OBJECTIVES: The aim of this study was to examine the effects of a per capita based remuneration system on the quality of dental care. METHODS: The basis for the study was a natural experiment in the county of Østfold in Norway in which all public dental officers (n = 34) were given ...
Parham Peter P Department of Structural Biology, Stanford University, Stanford, California 94305, USA. - - 2013
Natural killer (NK) cells have roles in immunity and reproduction that are controlled by variable receptors that recognize MHC class I molecules. The variable NK cell receptors found in humans are specific to simian primates, in which they have progressively co-evolved with MHC class I molecules. The emergence of the ...
Hudson Peter - - 2013
BACKGROUND: Palliative care is expected to incorporate comprehensive support for family caregivers given that many caregivers suffer psychological morbidity. However, systematically implemented evidence-based psychological support initiatives are lacking. AIM: The objective of this study was to prepare caregivers for the role of supporting a patient with advanced cancer receiving home-based ...
Carter Melondie R - - 2013
The number of nurses working in community-based practices with a population focus is increasing rapidly, whereas the rate of employment for nurses in hospitals is expected to grow more slowly. The shift in health care toward primary health care and health promotion requires nurse educators to ensure that students learn ...
Schag K K Department of Psychosomatic Medicine and Psychotherapy, University of Tübingen, Tübingen, Germany. - - 2013
Impulsivity towards food has been recognized as a potential factor leading to increased food intake in obesity. Patients suffering from binge eating disorder (BED) form a specific subgroup of obese people that might be characterized by increased impulsivity. These assumptions, although, have yet to be verified. Therefore, this review evaluates ...
Gore Anil H - - 2013
A novel, simple but highly selective fluorescent probe is developed for the direct detection of sulfide ions [S(2-)] based on the fluorescence quenching of the functionalized CdS QDs in aqueous solution at trace levels and successfully applied for quantitation of S(2-) from water samples in a complex matrix pretreatment exclusive ...
Hinterwirth Helmut - - 2013
Gold nanoparticles (GNPs) are often used as colloidal carriers in numerous applications owing to their low-cost and size-controlled preparation as well as their straightforward surface functionalization with thiol containing molecules forming self-assembling monolayers (SAM). The quantification of the ligand density of such modified GNPs is technically challenging, yet of utmost ...
Riar Sandeep K - - 2013
BACKGROUND: Restless legs syndrome (RLS) is considerably more common among adults with chronic kidney disease (CKD) than in the general population and is associated with increased morbidity and mortality. There is limited information on RLS in children with CKD. Failure to account for conditions that might mimic RLS can lead ...
Muuka Geoffrey Munkombwe - - 2013
Contagious bovine pleuropneumonia (CBPP) is a disease of economic importance that is widely distributed in sub-Saharan African and contributes significantly to cattle morbidity and mortality. Lack of resources to implement eradication measures has led to the disease becoming endemic in most areas in sub-Saharan Africa where governments have little resources ...
Wright M T - - 2013
Following the principles of participatory health research, a collaborative study was conducted by the German Federal Association for Prevention and Health Promotion (BVPG) and the Institute for Social Health at the Catholic University of Applied Sciences Berlin (KHSB). The purpose of the study was to create a framework for the ...
Lee Bao-Hong - - 2013
Hyperglycemia is associated with advanced glycation end products (AGEs). This study was designed to evaluate the inhibitory effects of monascin (MS) on receptor for advanced glycation end product (RAGE) signal and THP-1 monocyte inflammation after treatment with S100b, a specific ligand of RAGE. MS inhibited cytokine production by S100b-treated THP-1 ...
Salvati Anna A Centre for BioNano Interactions, School of Chemistry and Chemical Biology, UCD Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, - - 2013
Nanoparticles have been proposed as carriers for drugs, genes and therapies to treat various diseases. Many strategies have been developed to target nanomaterials to specific or over-expressed receptors in diseased cells, and these typically involve functionalizing the surface of nanoparticles with proteins, antibodies or other biomolecules. Here, we show that ...
Ponce Campos Guillermo E - - 2013
Climate change is predicted to increase both drought frequency and duration, and when coupled with substantial warming, will establish a new hydroclimatological model for many regions. Large-scale, warm droughts have recently occurred in North America, Africa, Europe, Amazonia and Australia, resulting in major effects on terrestrial ecosystems, carbon balance and ...
Chung-Davidson Yu-Wen - - 2013
ABSTRACT: BACKGROUND: Vertebrate pheromones are known to prime the endocrine system, especially the hypothalamic-pituitary-gonadal (HPG) axis. However, no known pheromone molecule has been shown to modulate directly the synthesis or release of gonadotropin releasing hormone (GnRH), the main regulator of the HPG axis. We selected sea lamprey (Petromyzon marinus) as ...
Mojtabai Ramin - - 2013
RATIONALE: Past research on the association of antidepressant medication use with glycemic control abnormalities has produced mixed results. OBJECTIVE: To examine the association of antidepressant use with glycemic control abnormalities and screen-positive diabetes in a representative population sample of US adults without a diagnosis of diabetes. METHODS: Using data from ...
Pasotti Fabio - - 2013
Abnormalities in plasma von Willebrand factor (vWF) concentration and function result in von Willebrand disease (vWD). The diagnosis requires a battery of tests such as screening procedures, confirmatory tests, phenotypic characterization and genotyping. The phenotypic testing (multimer pattern analysis) is important in order to subclassify the hereditary and the acquired ...
Jain Sachin Kumar Amruthlal - - 2013
BACKGROUND: Implantable cardioverter defibrillators (ICDs) have become an important part of the management of patients with congestive heart failure. At the time of ICD implantation, ventricular fibrillation (VF) is induced to assess adequate energy required for defibrillation. There are multiple parameters which influence the defibrillation safety margin (DSM); however, these ...
Miskin Marc Z - - 2013
Over 200 years after Coulomb's studies, a general connection between the mechanical response of a granular material and the constituents' shape remains unknown. The key difficulty in articulating this relationship is that shape is an inexhaustible parameter, making its systematic exploration infeasible. Here we show that the role of particle ...
Keith McInnes D - - 2013
Patient electronic personal health record (PHR) use has been associated with improved patient outcomes in diabetes and depression care. Little is known about the effect of PHR use on HIV care processes and outcomes. We evaluated whether there was an association between patient PHR use and antiretroviral adherence. Data came ...
Hänelt Inga - - 2013
Glt(Ph) is a Pyrococcus horikoshii homotrimeric Na(+)-coupled aspartate transporter that belongs to the glutamate transporter family. Each protomer consists of a trimerization domain involved in subunit interaction and a transporting domain with the substrate-binding site. Here, we have studied the conformational changes underlying transport by Glt(Ph) using EPR spectroscopy. The ...
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