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Results 351 - 400 of 3024
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Plevnik Kapun Alja - - 2013
Background: Altered homeostasis of vitamin E has been demonstrated in human atopic dermatitis. Data on plasma and skin vitamin E concentrations in canine atopic dermatitis (CAD) are not available. Objective: To determine vitamin E concentrations in plasma and skin of atopic dogs. Animals and Methods: Vitamin E concentrations in plasma ...
Kryukov Fedor - - 2013
ABSTRACT In multiple myeloma (MM), biologic complexity originates from complex oncogenic processes involving somatic acquisition of myriad mutations coupled with genetic variability within the host. This pathogenically determined molecular heterogeneity predetermines clinical intricacy. In this study, we performed gene expression profiling (GEP) focusing on centrosome-related genes to determine the molecular ...
Bouhenni Rachida - - 2013
To immunolocalize corneal keratan sulfate (KS) and its core protein lumican, aggrecan, type I and type III collagens in sclerocornea specimens and compare their expression and distribution to age-matched healthy corneas and scleras. Sclerocornea specimens (n = 3) and age-matched normal corneoscleral rim specimens (n = 3) were studied by light microscopy and histochemically. ...
Liu Fu-Yao - - 2013
Although the role of Krüppel-like factor 17 (KLF17) in regulating epithelial-mesenchymal transition (EMT) has been explored in breast cancer, its influence on primary hepatocellular carcinoma (HCC) remains unclear. This study aims to investigate the expression status of KLF17 in hepatocellular carcinoma (HCC) and the correlation between KLF17 expression and metastatic ...
McCann Edward - - 2013
International policy initiatives have highlighted the need to include older lesbian, gay, bisexual and transgender (LGBT) issues in the provision of appropriate health and social care. However, empirical studies in the area remain sparse. The aim of this study was to investigate the experiences and needs of LGBT people over ...
Ben-Ami Shor Dana - - 2013
The incidence of autoimmune diseases is increasing in Western countries, possibly due to the improved sanitary conditions and reduced exposure to infections in childhood (the hygiene hypothesis). There is an ongoing debate whether infection prevents or precipitates autoimmune diseases. Various helminths species used in several animal models were shown to ...
Zhang Mingyang - - 2013
Hydrogen sulfide (H(2)S) is a lipid-soluble, endogenously produced gaseous messenger molecule collectively known as gasotransmitter. Over the last several decades, gasotransmitters have emerged as potent cytoprotective mediators in various models of tissue and cellular injury. In this study, we performed a weight-drop traumatic brain injury (TBI) model in adult mice ...
Park Young Mi - - 2013
PURPOSE.: The purpose of our study was to evaluate the imaging features of benign adenomyoepithelioma of the breast with a focus on sonographic (US) appearances. METHODS.: Ten benign adenomyoepitheliomas in 9 patients were included in this study. Mammographic and US findings were analyzed retrospectively by 2 radiologists according to the ...
Hu Huaqing - - 2013
The cardio-ankle vascular index (CAVI) has been widely accepted as a good indicator of arteriosclerosis. However, the lack of a reliable diagnostic criterion for CAVI hampers the proper clinical screening for arteriosclerosis using CAVI and impedes the prompt treatment of cardiovascular disease (CVD). There is an urgent need to determine ...
Kalliomäki Jarkko - - 2013
The aim was to investigate the effects of AZD1940, a novel peripherally acting cannabinoid CB(1) / CB(2) receptor agonist, on capsaicin-induced pain and hyperalgesia, as well as on biomarkers of cannabinoid central nervous system (CNS) effects This was a randomized, double-blind, placebo-controlled, 4-sequences, 2-periods cross-over study in 44 male healthy ...
Chen Gang - - 2013
This study aimed to investigate the expression of the Nemo-like kinase (NLK) in the brain after experimental subarachnoid hemorrhage (SAH) in rats. A total of 90 rats were randomly divided into six groups: control group, day 1, day 3, day 5, day 7, and day 14. Day 1, day 3, ...
Tariq Anam - - 2013
Diabetic maculopathy is one of the retinal abnormalities in which a diabetic patient suffers from severe vision loss due to the affected macula. It affects the central vision of the person and causes blindness in severe cases. In this article, we propose an automated medical system for the grading of ...
Kasim Neda R - - 2013
The effect of actinomycin D on HeLa cells was studied by live fluorescence and transmission-through-dye microscopy-a recently developed technique that permits volume measurements in live cells. In particular, it is well suited for the observation and quantification of the apoptotic volume decrease (AVD), which is widely viewed as an essential ...
Enríquez-Navascués J M - - 2013
Restoration of intestinal continuity at a second stage after emergency total proctocolectomy may be difficult or hazardous due to the pelvic cavity being closed off. We present a way of keeping the pelvic cavity open and accessible following total proctocolectomy by insertion of a breast implant that hinders fibrosis and ...
Kono Kiyomi - - 2013
Basic fibroblast growth factor (bFGF) is a cytokine that promotes the regeneration of the periodontium, the specialized tissues supporting the teeth. bFGF, does not, however, induce the synthesis of smooth muscle actin alpha 2 (ACTA2), type I collagen (COL1), or COL3, which are principal molecules in periodontal ligament (PDL) tissue, ...
Kristjánsson Arni - - 2013
Priming of visual search has a dominating effect upon attentional shifts and is thought to play a decisive role in visual stability. Despite this importance, the nature of the memory underlying priming remains controversial. To understand more fully the necessary conditions for priming, we contrasted passive versus active viewing of ...
Gil V - - 2013
Background  Pharmacological studies using selective P2Y(1) antagonists, such as MRS2500, and studies with P2Y(1) (-/-) knockout mice have demonstrated that purinergic neuromuscular transmission is mediated by P2Y(1) receptors in the colon. The aim of the present study was to test whether P2Y(1) receptors are involved in purinergic neurotransmission in the ...
Ellenberger Sarah - - 2013
A 3 mo old female Airedale terrier presented with decreased range of motion of the temporomandibular joint (TMJ), which was first recognized at weaning. Computed tomography (CT) revealed abnormal, bilateral ossification of the soft tissues extending from the region of the tympanic bullae to the medial aspect of the angular ...
Barendse H P J - - 2013
In geriatric psychiatry, informant reports are often important due to cognitive problems and related impaired insight and judgment. Informant questionnaires to identify personality traits among older adults are sparse. The Dutch informant personality questionnaire (the HAP) is especially developed to address this need. The objective of this study is the ...
Murphy R - - 2013
BACKGROUND: Rates of unemployment and early retirement are increased in Parkinson's disease (PD) and contribute to disease burden. AIMS: To investigate time to loss of employment from PD onset and predictors of continued employment; to identify common issues and possible interventions in the workplace. METHODS: Eighty-eight patients with PD diagnosed ...
Singh Sundeep - - 2013
BACKGROUND: N-acetylcysteine (NAC) improves transplant-free survival in early coma grade (I-II) patients with non-acetaminophen induced acute liver failure (ALF). We determined whether the clinical benefit was associated with improvements in hepatic function. METHODS: In a prospective, double blind trial, 173 ALF patients without evidence of acetaminophen overdose were stratified by ...
Oefelein Michael G - - 2013
BACKGROUND: Overactive bladder (OAB) is often associated with a number of co-morbid medical conditions, including diabetes mellitus. This may necessitate several concomitant treatments, thus creating the potential for drug-drug interactions (DDIs). Trospium is renally eliminated, not metabolized via cytochrome P450; therefore, cytochrome P450 DDIs are unlikely. However, coadministration with another ...
Ando Hitoshi - - 2013
Raloxifene, a selective oestrogen receptor modulator commonly used for the treatment of postmenopausal osteoporosis, affects the coagulation and fibrinolytic systems and consequently increases the risk of venous thromboembolism. Because both the coagulation and fibrinolytic systems exhibit circadian rhythms, we aimed to investigate the influences of dosing time of raloxifene on ...
Trilles Jean-Paul - - 2013
Eleven Nerocila species are recorded from 22 marine fishes belonging to 15 families. Three, Nerocila arres, Nerocila depressa, and Nerocila loveni, are new for the Indian fauna. N. arres and Nerocila sigani, previously synonymized, are redescribed and their individuality is restored. Nerocila exocoeti, until now inadequately identified, is described and ...
Tierney Jessica E - - 2013
The recent decades-long decline in East African rainfall suggests that multidecadal variability is an important component of the climate of this vulnerable region. Prior work based on analysing the instrumental record implicates both Indian and Pacific ocean sea surface temperatures (SSTs) as possible drivers of East African multidecadal climate variability, ...
Morelli Michele - - 2013
Abstract The aim of this study was to evaluate the improvement in catamenial chronic pelvic pain (CPP) after Gonadotropin Releasing Hormone analogue (GnRH-a) administration in women affected by adenomyosis or endometriosis. We retrospectively analysed clinical data of 63 premenopausal women with clinical suspect of adenomyosis (15 women, Group A) or ...
Oliveira Maiolino Thomaz Fonseca - - 2013
BACKGROUND: Reconstruction of mandibular defects after tumor resection is a challenge to the head and neck surgeon because of associated functional and esthetic problems. The intention of mandibular reconstructive surgery is to achieve maximum possible functionality, which means the restoration of masticatory function and speech with a good esthetic result. ...
Verkooijen Kirsten T - - 2013
Possible interactions among exercise self-identity, social comparison and exercise behaviour were explored in a sample of 417 undergraduate students (Mean age = 21.5, SD = 3.0; 73% female). Two models were examined using self-report data; (1) a mediation model which proposed an association between social comparison and exercise behaviour mediated by exercise self-identity and ...
Kare Pavan - - 2013
Parkinson's disease (PD) is a degenerative disorder of the CNS, characterized by cerebral depletion of dopamine (DA), hence one of the approaches to delay the depletion of DA is to inhibit its oxidative deamination. Monoamine oxidases (MAO) carry out the oxidative deamination of monoamines like DA. These are intracellular enzymes, ...
Godwin Kyler M - - 2013
Objective: Functional impairment resulting from a stroke frequently requires the care of a family caregiver, often the spouse. This change in the relationship can be stressful for the couple. Thus, this study examined the longitudinal, dyadic relationship between caregivers' and stroke survivors' mutuality and caregivers' and stroke survivors' perceived stress. ...
Diderichsen Paul Matthias - - 2013
AIM: To assess the cardiovascular effects of a new inhaled long-acting beta agonist PF-00610355 in COPD Patients. METHODS: 13,062 heart rate measurements collected in 10 clinical studies from 579 healthy volunteers, asthma, and COPD patients, were analyzed. The relationship between heart rate profiles and predicted plasma concentration profiles, patient status, ...
El-Sisi A A - - 2013
This study aimed at comparing the effects of atorvastatin and vitamin E on erectile dysfunction in patients initially irresponsive to sildenafil, with investigation into the underlying possible mechanisms. Sixty patients were randomly divided into three groups: the atorvastatin group received 80 mg daily, the vitamin E group received 400 IU daily and ...
Lin Janet Y - - 2013
Introduction Emergency medical care in Pakistan has not been a priority of medical education and training because of the country's need to address its lack of primary care. Resources and trained personnel are scarce. Despite these challenges, the value of emergency medical care is gaining attention. The objective of this ...
Sheehan Jane - - 2013
BACKGROUND: In children with cystic fibrosis (CF) sleep, eating/mealtime, physiotherapy adherence and internalising problems are common. Caregivers also often report elevated depression, anxiety and stress symptoms. PURPOSE: To identify, through principal components analysis (PCA), coping strategies used by Australian caregivers of children with CF and to assess the relationship between ...
Alrabiah Haitham - - 2013
Fourier transform infrared (FT-IR) spectroscopy is an established rapid whole-organism fingerprinting method that generates metabolic fingerprints from bacteria that reflect the phenotype of the microorganism under investigation. However, whilst FT-IR spectroscopy is fast (typically 10 s to 1 min per sample), the approaches for microbial sample preparation can be time ...
Randler Christoph - - 2013
Mobbing of predators occurs within a conspecific and heterospecific context but has not been quantified within the framework of a communication network and analysed with respect to heterospecific reciprocity. Here, we used playbacks of mobbing calls to show that mobbing is unequally distributed within a community of deciduous forest birds. ...
Costa Danielle Cristina Machado - - 2013
Abstract Lippia alba (Miller) N.E. Brown is an aromatic plant known locally as "Erva-cidreira-do-campo" that has great importance in Brazilian folk medicine. The aim of our study was to evaluate the antidermatophytic potential of linalool-rich essential oil (EO) from L. alba and analyze the ability of this EO to inhibit ...
Alvarez Nicolas Javier - - 2013
We introduce a new field-flow fractionation (FFF) technique, whereby molecules are separated based on their differential interaction (dielectrophoresis (DEP)) with optical electric fields, i.e. electric fields with frequencies in the visible and near-infrared range. The results show that a parallel array of axially non-uniform optical fields yielding an attractive potential ...
Chen Zhong - - 2013
A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR.
Ai Wenqing - - 2013
Induction of local (pulmonary) immunity plays a critical role in preventing dissemination of Mycobacterium tuberculosis (M. tb) at the early infection stage. On the basis of our previously constructed multi-epitope gene vaccine, pHSP65pep, which effectively induced splenic IFN-γ(+) Th1 response, chitosan, one natural cationic polysaccharide was employed as mucosal gene ...
Gullai Nóra - - 2013
The aim of this study was to investigate the diagnostic accuracy of the Triage placental growth factor (PlGF) assay, together with its prognostic efficiency in determining the need for preterm delivery in all forms of hypertensive disorders of pregnancy. A total of 130 pregnant women with a diagnosis of preeclampsia ...
Zebarjadi Mona - - 2013
Nanoparticle dopants are designed which are invisible to conduction electrons and have sharp dips in their electron scattering rate versus electron energy close to the Fermi level. Replacement of such dopants with traditional impurities results in simultaneous enhancement of the Seebeck coefficient and the electron mobility and therefore a large ...
Kumar R - - 2013
This paper presents the analysis of large mining machinery related accidents in Indian opencast coal mines. The trends of coal production, share of mining methods in production, machinery deployment in open cast mines, size and population of machinery, accidents due to machinery, types and causes of accidents have been analysed ...
Casey Baretta R - - 2013
Women in Appalachian Kentucky experience a high burden of cervical cancer and have low rates of human papillomavirus (HPV) vaccination. The purpose of this study was to identify normative influences predicting initial HPV vaccine uptake among a sample of young women in southeastern Kentucky. Women (N = 495), ages 18 through 26 years, ...
Liu Lifeng - - 2013
In the highly active antiretroviral therapy era, the incidence of human immunodeficiency virus (HIV)-associated neurocognitive disorder remains high with the improved survival. The prevalence of resistance differs across geographical areas and HIV subtypes. Currently, little information on the resistance patterns in the central nervous system (CNS) is available in Chinese ...
Chen Caixia - - 2013
In the course of a screening program for bioactive compounds from a marine natural product library, a newly isolated Actinomycetes strain, designated as MS100061, exhibited strong anti-Mycobacterium bovis Bacillus Calmette-Guérin (BCG) activity. The strain belongs to the genus Streptomyces according to its morphological and 16S rDNA phylogenetic analysis. Bioassay-guided isolation ...
Pappa Kalliopi I - - 2013
Abstract Dysfunction of the circadian clock genes is involved in the development of obesity and type 2 diabetes (T2D). Since gestational diabetes mellitus (GDM) and T2D share common genetic and phenotypic features, in the present study, we investigated the status of the circadian clock in a cohort of 40 Greek ...
Wawrzyniak Agata - - 2013
PURPOSE: Concentration of carotenoids in the serum is a biomarker of mainly vegetable and fruit consumption. However, the levels of carotenoids in humans may decline with age and can also depend on body fat, alcohol consumption, and cigarette smoking. METHOD: Food intake and characteristics of 159 randomly chosen women aged ...
Vajpai Navratna - - 2013
Members of the fibroblast growth factor receptor tyrosine kinase family (FGFR1-4) play an important role in many signalling cascades. Although tightly regulated, aberrant activity of these enzymes may lead to, or become features of, disease pathologies including cancer. FGFR isoforms have been the subject of drug discovery programmes, with a ...
Somel Mehmet - - 2013
What evolutionary events led to the emergence of human cognition? Although the genetic differences separating modern humans from both non-human primates (for example, chimpanzees) and archaic hominins (Neanderthals and Denisovans) are known, linking human-specific mutations to the cognitive phenotype remains a challenge. One strategy is to focus on human-specific changes ...
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