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Results 251 - 300 of 3031
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Barendse H P J - - 2013
In geriatric psychiatry, informant reports are often important due to cognitive problems and related impaired insight and judgment. Informant questionnaires to identify personality traits among older adults are sparse. The Dutch informant personality questionnaire (the HAP) is especially developed to address this need. The objective of this study is the ...
Murphy R - - 2013
BACKGROUND: Rates of unemployment and early retirement are increased in Parkinson's disease (PD) and contribute to disease burden. AIMS: To investigate time to loss of employment from PD onset and predictors of continued employment; to identify common issues and possible interventions in the workplace. METHODS: Eighty-eight patients with PD diagnosed ...
Singh Sundeep S Division of Gastroenterology and Hepatology, Stanford University, 300 Pasteur Drive, Stanford, CA 94305-5187, USA. - - 2013
N-acetylcysteine (NAC) improves transplant-free survival in early coma grade (I-II) patients with non-acetaminophen induced acute liver failure (ALF). We determined whether the clinical benefit was associated with improvements in hepatic function. In a prospective, double blind trial, 173 ALF patients without evidence of acetaminophen overdose were stratified by coma grade ...
Oefelein Michael G - - 2013
BACKGROUND: Overactive bladder (OAB) is often associated with a number of co-morbid medical conditions, including diabetes mellitus. This may necessitate several concomitant treatments, thus creating the potential for drug-drug interactions (DDIs). Trospium is renally eliminated, not metabolized via cytochrome P450; therefore, cytochrome P450 DDIs are unlikely. However, coadministration with another ...
Ando Hitoshi - - 2013
Raloxifene, a selective oestrogen receptor modulator commonly used for the treatment of postmenopausal osteoporosis, affects the coagulation and fibrinolytic systems and consequently increases the risk of venous thromboembolism. Because both the coagulation and fibrinolytic systems exhibit circadian rhythms, we aimed to investigate the influences of dosing time of raloxifene on ...
Trilles Jean-Paul - - 2013
Eleven Nerocila species are recorded from 22 marine fishes belonging to 15 families. Three, Nerocila arres, Nerocila depressa, and Nerocila loveni, are new for the Indian fauna. N. arres and Nerocila sigani, previously synonymized, are redescribed and their individuality is restored. Nerocila exocoeti, until now inadequately identified, is described and ...
Goh Kian Mau - - 2013
The Bacillaceae family members are a good source of bacteria for bioprocessing and biotransformation involving whole cells or enzymes. In contrast to Bacillus and Geobacillus, Anoxybacillus is a relatively new genus that was proposed in the year 2000. Because these bacteria are alkali-tolerant thermophiles, they are suitable for many industrial ...
Klaus Anita - - 2013
Hot water extract (LN), partially purified polysaccharides (LP) and hot alkali extracted polysaccharides (LNa) obtained from fruiting bodies of the wild basidiomycete Laetiporus sulphureus were examined for their antioxidant activities. LNa was the most active antioxidant, as shown by the median effective concentrations (EC(50) values) of 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity ...
Baki Yasin - - 2013
ABSTRACT: BACKGROUND: Most phylogeny analysis methods based on molecular sequences use multiple alignment where the quality of the alignment, which is dependent on the alignment parameters, determines the accuracy of the resulting trees. Different parameter combinations chosen for the multiple alignment may result in different phylogenies. A new non-alignment based ...
Menachem Assaf - - 2013
Excessive influx of immunoglobulin (IgG) into the brain has been reported to induce central nervous system (CNS) dysfunction. Depressed patients may exhibit immune activation manifested by elevated inflammatory markers and pro-inflammatory cytokines. The brain and especially the limbic system contain high concentrations of high affinity Fc receptors. We reviewed the ...
Golzari Mana - - 2013
Abstract Aim: Adolescents in the juvenile justice system are particularly susceptible to high rates of co-occurring health-risk behaviors, while at the same time lacking access to the healthcare system. Methods: A verbal questionnaire was administered from December 2009 to June 2010 to youth between the ages of 13-17 years old, ...
Wu Xing-De - - 2013
A new tigliane diterpenoid, acerifolin A (1), and a new isopimarane diterpenoid, acerifolin B (2), together with two known compounds, were isolated from Excoecaria acerifolia. Their structures were elucidated on the basis of their spectroscopic methods, including 1D and 2D NMR techniques. All of the compounds were evaluated for cytotoxicity ...
Voorn Veronique M A - - 2013
The subject of the study is to investigate whether health-related quality of life (HRQoL), pain and function of patients with hip or knee osteoarthritis (OA) improves after a specialist care intervention coordinated by a physical therapist and a nurse practitioner (NP) and to assess satisfaction with this care at 12 weeks. ...
Egunsola Oluwaseun - - 2013
PURPOSE: To determine the safety of fluconazole in neonates and other paediatric age groups by identifying adverse events (AEs) and drug interactions associated with treatment. METHODS: A search of EMBASE (1950-January 2012), MEDLINE (1946-January 2012), the Cochrane database for systematic reviews and the Cumulative Index to Nursing and Allied Health ...
Stamm Fernanda P - - 2013
Reversed-phase liquid chromatography (RP-LC) and size exclusion liquid chromatography (SE-LC) methods were validated for the assessment of recombinant human parathyroid hormone (rhPTH 1-34). The gradient RP-LC method was carried out on a Zorbax 300 SB C(18) column (150 mm × 4.6 mm i.d.), maintained at 40 °C. The mobile phase ...
Fontaine Laetitia - - 2013
In many streptococci, competence for natural DNA transformation is regulated by the Rgg-type regulator ComR and the pheromone ComS, which is sensed intracellularly. We compared the ComRS systems of four model streptococcal species using in vitro and in silico approaches, to determine the mechanism of the ComRS-dependent regulation of competence. ...
Nakano Miyo - - 2013
We developed a quantitative real-time PCR assay to specificity detect and quantify the genus Alcaligenes in samples from the agricultural environment, such as vegetables and farming soils. The minimum detection sensitivity was 106 fg of pure culture DNA, corresponding to DNA extracted from two cells of A. faecalis. To evaluate ...
Tetlow Daniel J - - 2013
Deprotonation with strong bases of N-vinyl ureas carrying an N'-aryl substituent leads to migration of the N'-aryl group from N to C via an allyllithium; with weaker bases and electron-deficient aryl rings the direction of the migration reverses, and aryl substituents α to the urea N atom may migrate from ...
Wu Qiong - - 2013
The heats of formation (HOFs), electronic structure, energetic properties, and thermal stabilities for a series of 1,4-bis(1-azo-2,4-dinitrobenzene)-iminotetrazole derivatives with different substituents and substitution positions and numbers of nitrogen atoms in the nitrobenzene rings were studied using the DFT-B3LYP method. All the substituted compounds have higher HOFs than their parent compounds. ...
Gajjar Ketan - - 2013
Currently available screening tests do not deliver the required sensitivity and specificity for accurate diagnosis of ovarian or endometrial cancer. Infrared (IR) spectroscopy of blood plasma or serum is a rapid, versatile, and relatively non-invasive approach which could characterize biomolecular alterations due to cancer and has potential to be utilized ...
Akabayov Sabine R - - 2013
Controlling translation during protein synthesis is crucial for cell proliferation and differentiation. Protein translation is orchestrated by an assembly of various protein components at the ribosomal subunits. The eukaryotic translation initiation factor 4G (eIF4G) plays an important role in the formation of the translation initiation complex eIF4F consisting of eIF4G, ...
Inci Mehmet - - 2013
Abstract Objective. There are limited data on whether there is an association between nocturia, benign prostatic hyperplasia (BPH) and endothelial dysfunction. The aim of the present study was to evaluate whether there is an association between nocturia and endothelial dysfunction in patients with BPH. Material and methods. Forty-two men with ...
Zhang Sai-Yang - - 2013
A new C(18)-diterpenoid alkaloid, kirinenine A (1), was isolated from the root of Aconitum kirinense, along with eight known diterpenoid alkaloids. The structures of all compounds were characterized on the basis of extensive NMR and MS analyses and by comparison with literature values, and the new one was further confirmed ...
Proulx Steven T ST Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Wolfgang-Pauli-Str. 10, HCI H303, 8093 Zurich, - - 2013
Preclinical vascular research has been hindered by a lack of methods that can sensitively image and quantify vascular perfusion and leakage in vivo. In this study, we have developed dynamic near-infrared imaging methods to repeatedly visualize and quantify vascular leakage in mouse skin in vivo, and we have applied these ...
Kaur Taranjeet - - 2013
The genetic diversity of the endangered crocodile Tomistoma schlegelii was characterized using the protein coding ND 6-tRNA(glu)-cyt b and the cytochrome b-control region (cyt b-CR) markers. Concatenate data revealed six haplotypes with an overall haplotype diversity of 0.769 ± 0.039; nucleotide diversity was 0.00535 ± 0.00172. A nearest-neighbor analysis showed that all individuals clustered ...
Lee Young Ho - - 2013
The aim of this study was to determine whether toll-like receptor (TLR) polymorphisms confer susceptibility to rheumatoid arthritis (RA) and influence the clinical characteristics of RA. The authors conducted a systematic review on associations between TLR polymorphisms and RA susceptibility and clinical findings. Meta-analysis was performed if at least three ...
Lee Eun-Jeong - - 2013
Asian students comprise over half of all international students in the United States, yet little is known about their help-seeking behaviors and preferences for mental health professionals. The purpose of this study was to use conjoint analysis to examine characteristics of mental health professionals influencing Korean international students' preferences when ...
Anagnostopoulos Fotios - - 2013
PURPOSE: To investigate the dimensionality, construct validity in the form of factorial, convergent, discriminant, and known-groups validity, as well as scale reliability of the fifteen dimensional (15D) instrument. METHODS: 15D data were collected from a large Greek general population sample (N = 3,268) which was randomly split into two halves. Data from ...
Tiruthani Karthik - - 2013
Molecular mechanisms regulating human trophoblast differentiation remain poorly understood due to difficulties in obtaining primary tissues from very early developmental stages in humans. Therefore, the use of human embryonic stem cells (hESCs) as a source for generating trophoblast tissues is of significant interest. Trophoblast-like cells have been obtained through treatment ...
Nicholls Daniel - - 2013
This article presents the mental health aspects of 'touch' associated with a funded research project: Avoiding 'high tech' through 'high touch' in end-stage dementia: Protocol for care at the end-of-life. These mental health aspects highlight the human need for touch that continues up until and inclusive of the final stages ...
Lee Chang-Hyun - - 2013
BACKGROUND: Advancements over the past generation have yielded several new treatment options for the management of brain metastases. However, surgical resection (SR) still remains the mainstay of treatment and is performed especially if decompression is required. The goal of this study was to evaluate the role of surgical resection for ...
de Paula Natália Aparecida NA Laboratório de Genética Toxicológica, Departamento de Biologia Geral, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Rod. Celso Garcia Cid, Pr 445 Km 380, CEP 86055-990, Londrina, Paraná, Brazil, - - 2013
Nicorandil is a nitric oxide (NO) donor used in the treatment of angina symptoms. It has also been reported to protect cells and affect the proliferation and death of cells in some tissues. The molecules that interfere with these processes can cause dysfunction in healthy tissues but can also assist ...
Rasolofoarivao Henriette - - 2013
Varroa destructor is a major pest in world beekeeping. It was first detected in Madagascar in 2010 on the endemic honeybee Apis mellifera unicolor. To evaluate V. destructor spread dynamics in Madagascar a global survey was conducted in 2011-2012. A total of 695 colonies from 30 districts were inspected for ...
Wertman Jaime - - 2013
Abstract G protein-coupled receptors (GPCRs) represent the largest group of cell surface receptors and an important pharmacological target. Though originally thought to act in a one receptor-one effector fashion, it is now known that these receptors are capable of oligomerization and can function as dimers or higher order oligomers in ...
Bai Wei - - 2013
OBJECTIVE: This prospective non-randomized controlled trial was aimed to compare the efficacy of sorafenib in combination with transarterial chemoembolization (TACE) versus TACE alone for treatment of patients with unresectable intermediate/advanced stage hepatocellular carcinoma (HCC). METHODS: A total of 304 patients were enrolled and all treated with TACE, 82 of the ...
Roehler Douglas R - - 2013
Motorcycle fatalities are increasing at an alarming rate in many South-East Asian countries, including Cambodia. Through brief face-to-face roadside interviews in Phnom Penh and four other Cambodian provinces, this article assesses Cambodian motorcyclists' attitudes, behaviours and beliefs related to motorcycle helmets. Out of 1016 motorcyclists interviewed, 50% were drivers, 40% ...
Davenport Michael T - - 2013
The issue of antenatal hydronephrosis has become a routine component for the care of a pregnant woman despite limited evidence of a clinical benefit. The genitourinary tract represents the most commonly detected organ system with identified abnormalities, with antenatal hydronephrosis (ANH), being the most notable and common finding. ANH represents ...
Smee Nicole - - 2013
There are multiple considerations when making a treatment plan for patients with urinary tract infections (UTIs). In part 2 of this review the authors discuss the clinical signs, diagnosis, treatment, and complications associated with bacterial UTIs in dogs and cats. Part 1 of this review summarized etiology and pathogenesis (see ...
Hodgson K - - 2013
Evidence has emerged supporting a link between high glycaemic index (GI) diets and type 2 diabetes (T2D). The aim of this study was to determine if dietary GI influences the development of hyperglycaemia in C57BL/6 mice to more closely reflect T2D. Male C57BL/6 mice (n=30) were randomly divided into 3 ...
Lei Jianyong - - 2013
BACKGROUND: In Mainland China, many selection criteria for hepatocellular carcinoma (HCC) liver transplantation, such as the Hangzhou, the Chengdu, and the Fudan criteria, have been established. No comparisons have been made among the outcomes using the Hangzhou, Chengdu, and University of California, San Francisco (UCSF) criteria in patients who underwent ...
Koriyama Masumi - - 2013
To investigate seasonal variations of nutrient distribution in the mudflat-shallow water system, we conducted field surveys once a month from August 2007 to July 2008 in the inner area of Ariake Bay (IAB), Japan. The NH(4) (+)-N concentration of the water column increased in autumn because of the high NH(4) ...
Chen Yunhua - - 2013
High Internal Phase Emulsion hydrogels are prepared from waterborne poly(N-isopropylacrylamide) nanogel dispersions which are non-covalently crosslinked through 2-ureido-4[1H] pyrimidinone (UPy) quadruple hydrogen bond groups. The reversible UPy crosslinks allow for the HIPE-hydrogels to be molded into objects which are thermo-responsive in nature.
Bateman Michael G - - 2013
A thorough understanding of valvar anatomy is essential for design engineers and clinicians in the development and/or employment of improved technologies or therapies for treating valvar pathologies. There are two arterial valves in the human heart-pulmonary and aortic valves. Both are complex structures whose normal anatomical components can vary greatly ...
Kotani Takuya - - 2013
The efficacy and safety of liposomal amphotericin B (L-AMB) in the treatment of invasive fungal infections (IFIs) were retrospectively evaluated for patients with connective tissue diseases (CTDs) during treatment with immunosuppressive therapy. Subjects were 13 patients with CTDs complicated by IFI, on the basis of clinical symptoms, imaging findings, and ...
Leite M L C - - 2013
Data from a population-based prospective study were used to examine longitudinal changes in blood pressure (BP) and seek interactions between apolipoprotein E (ApoE) genotypes, smoking and alcohol in a cohort of 557 elderly Brazilian men. Repeated BP measurements were obtained in four waves, and multi-level random-effects pattern-mixture models were used ...
Youk Ji Hyun - - 2013
To compare the mean elasticity value, as measured by shear-wave elastography (SWE), with immunohistochemical profile of invasive breast cancer. This was an institutional review board-approved retrospective study, with a waiver of informed consent. A total of 166 invasive breast cancers in 152 women undergoing preoperative SWE and surgery were included. ...
Oztürk A - - 2013
Öztürk, A. & Mollao─člu, M. (2013). Determination of problems in patients with post-laryngectomy. Scandinavian Journal of Psychology. The purpose of this study is the determination of the physical and psychosocial problems of total and partial laryngectomies. A total of 25 patients, who were operated with the diagnosis of larynx carcinoma ...
Helmberger Thomas - - 2013
Image-guided diagnostic and therapeutic procedures are related to, or performed under, some kind of imaging. Such imaging may be direct inspection (as in open surgery) or indirect inspection as in endoscopy or laparoscopy. Common to all these techniques is the transformation of optical and visible information to a monitor or ...
Vaclavik Lukas - - 2013
The availability of rapid and reliable tools for monitoring of plants' cold tolerance is a prerequisite for research aimed at breeding of cold-tolerant crop plants. Therefore, we have tested the capacity of metabolomics-based methods employing ultra-high-performance liquid chromatography (UHPLC)-mass spectrometry and direct analysis in real time-mass spectrometry for high-throughput screening ...
Gräff Johannes - - 2013
Long-lasting memories require specific gene expression programmes that are, in part, orchestrated by epigenetic mechanisms. Of the epigenetic modifications identified in cognitive processes, histone acetylation has spurred considerable interest. Whereas increments in histone acetylation have consistently been shown to favour learning and memory, a lack thereof has been causally implicated ...
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