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Results 201 - 250 of 3031
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Qi Xiaoying - - 2013
Graphene-based polymer nanocomposites have attracted increasing interest because of their superior physicochemical properties over polymers. Semiconductor conjugated polymers (CPs) with excellent dispersibility and stability, and efficient electronic and optical properties have been recently integrated with graphene to form a new class of functional nanomaterials. In this minireview, we will summarize ...
Bays Harold E - - 2013
BACKGROUND: Icosapent ethyl (IPE) is a high-purity prescription form of eicosapentaenoic acid ethyl ester approved by the US Food and Drug Administration as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia. In addition to TG-lowering effects, IPE also reduces non-high-density lipoprotein cholesterol ...
Ainslie B - - 2013
High resolution numerical atmospheric modeling around a mountain ridge in Northeastern British Columbia (BC), Canada was performed in order to examine the influence of meteorology and topography on Golden Eagle migration pathways at the meso-scale (tens of km). During three eagle fall migration periods (2007-2009), local meteorological conditions on the ...
- - 2013
Short-course antiretroviral therapy (ART) in primary human immunodeficiency virus (HIV) infection may delay disease progression but has not been adequately evaluated. We randomly assigned adults with primary HIV infection to ART for 48 weeks, ART for 12 weeks, or no ART (standard of care), with treatment initiated within 6 months ...
Yue Yong - - 2013
Two new pyrrolo[1,2-α]azepine-type stemona alkaloids, named as tuberostemonoxirine (1) and 9α-epi-tuberospironine (2), were isolated from the roots of Stemona tuberosa. The structures and relative configurations of new compounds were established on the basis of extensive spectroscopic evidences, especially 1D and 2D NMR and HR-MS experiments.
Stepita Meredith E - - 2013
Socialization is one method of preventing behavior problems in dogs; however, some oppose socialization before 16 wk of age due to the risk of contracting infectious diseases. The objectives of this study were to determine if puppies that attended puppy socialization classes and were vaccinated by a veterinarian at least ...
Iacovazzo D - - 2013
Double pituitary adenomas represent up to 2.6 % of pituitary adenomas in large surgical series and up to 3.3 % of patients with Cushing's disease have been found to have double or multiple pituitary adenomas. We report the case of a 60-year-old male patient whose medical history began in 2002 with erectile ...
Chiarandini Fiore Jessica Paola - - 2013
Natural and contaminated waters of the final reaches of the Chubut River (Patagonia, Argentina) were studied to obtain information about river organic matter and effects of domestic and industrial discharges (fishery effluents and sewages). Fluorescence Excitation-Emission Matrices (EEMs) were obtained from samples only filtered (0.45 μm) and diluted, if necessary, to ...
Pham Loan - - 2013
Abstract Twelve hydrophobic coating agents were assessed for their effects on drug release after coating sugar cores by a flexible hot-melt coating method using direct blending. Drug-containing pellets were also produced and used as cores. The cores were coated with single or double wax layers containing acetaminophen (APAP). The harder ...
Gleeson M - - 2013
BACKGROUND: The Health Service Executive introduced a generic prescription policy to reduce costs. Despite this, generic prescription rates remain low. AIM: To audit in-patient prescription practice in a single surgical department and identify potential savings which could be realised by adherence to the generic prescribing policy. METHODS: Surgical in-patient charts ...
Yang Yang - - 2013
The ferrocene/ferrocenium (Fc/Fc(+)) redox couple has been deemed one of the best candidates of the standard electrochemical reference for redox reactions in ionic liquids (ILs). To fully reveal the redox reaction mechanism in the IL condensed phase, solvation, as a prerequisite, apparently needs to be understood. As a preliminary attempt ...
Gadhe Changdev G - - 2013
Chemokine receptor 5 (CCR5) is an important receptor used by human immunodeficiency virus type 1 (HIV-1) to gain viral entry into host cell. In this study, we used a combined approach of comparative modeling, molecular docking, and three dimensional quantitative structure activity relationship (3D-QSAR) analyses to elucidate detailed interaction of ...
Duan Xiaoguang - - 2013
Lepidopteran insects affect cassava production globally, especially in intercropping system. The expression of Cry toxins in transgenic crops has contributed to an efficient control of insect pests, leading to a significant reduction in chemical insecticide usage. Helicoverpa armigera is a Lepidopteran pest that feeds on a wide range of plants ...
Singh Mini - - 2013
A combined analysis of a bovine and ovine mammary gland transcriptome from two similarly designed microarray experiments suggested a strong positive association between the differentially expressed genes (DEGs) implying that major pathways regulating the lactation process were evolutionarily conserved within the two species. Some distinct pathways identified indicate the physiological ...
Umeki Akihide - - 2013
Aiming the 'Bridge to Recovery' course, we have developed a novel left ventricular assist device (LVAD) controlling system. It can change the rotational speed of the continuous flow LVAD, EVAHEART, synchronized with the cardiac beat. Employing this system, we have already demonstrated that myocardial oxygen consumption (MVO2), which is considered ...
Beutner C - - 2013
Inflammation can be prevented in most inflammatory brain diseases, while tissue repair of the lesioned central nervous system (CNS) is still a major challenge. The CNS is difficult to access for protein therapeutics due to the blood-brain barrier. Here, we show that genetically engineered embryonic stem cell-derived microglia (ESdM) are ...
Birnbaum Tobias - - 2013
Methotrexate (MTX)-based chemotherapy is used as upfront treatment for most patients with primary CNS lymphoma. Whether consolidating whole brain irradiation (WBI) should be recommended for patients who achieve complete remission (CR) is still a matter of debate. Patients who are predicted to experience an early relapse (ER, ≤12 months from diagnosis) might ...
Ford Kathleen - - 2013
Previous research on migrant health indicates that social integration may exert a strong influence on health behavior. However, to our knowledge, this factor has not been integrated into models for HIV prevention. Drawing constructs from the Health Belief Model, the objective of this paper was to determine whether social integration, ...
Barcellos-Hoff Mary Helen - - 2013
Radiation exposure is a well-documented risk factor for breast cancer in women. Compelling epidemiological evidence in different exposed populations around the world demonstrate that excess breast cancer increases with radiation doses above 10 cGy. Both frequency and type of breast cancer are affected by prior radiation exposure. Many epidemiological studies suggest ...
Janssen Fanny - - 2013
We present a new mortality projection methodology that distinguishes smoking- and non-smoking-related mortality and takes into account mortality trends of the opposite sex and in other countries. We evaluate to what extent future projections of life expectancy at birth (e (0)) for the Netherlands up to 2040 are affected by ...
Santos Jorge M - - 2013
ABSTRACT: BACKGROUND: ECBio has developed proprietary technology to consistently isolate, expand and cryopreserve a well-characterized population of stromal cells from human umbilical cord tissue (UCX(R) cells). The technology has recently been optimized in order to become compliant with Advanced Medicine Therapeutic Products. In this work we report the immunosuppressive capacity ...
Tierney Jessica E - - 2013
The recent decades-long decline in East African rainfall suggests that multidecadal variability is an important component of the climate of this vulnerable region. Prior work based on analysing the instrumental record implicates both Indian and Pacific ocean sea surface temperatures (SSTs) as possible drivers of East African multidecadal climate variability, ...
Morelli Michele - - 2013
Abstract The aim of this study was to evaluate the improvement in catamenial chronic pelvic pain (CPP) after Gonadotropin Releasing Hormone analogue (GnRH-a) administration in women affected by adenomyosis or endometriosis. We retrospectively analysed clinical data of 63 premenopausal women with clinical suspect of adenomyosis (15 women, Group A) or ...
Oliveira Maiolino Thomaz Fonseca - - 2013
BACKGROUND: Reconstruction of mandibular defects after tumor resection is a challenge to the head and neck surgeon because of associated functional and esthetic problems. The intention of mandibular reconstructive surgery is to achieve maximum possible functionality, which means the restoration of masticatory function and speech with a good esthetic result. ...
Kumar Rahul R School of Mechanical Engineering, Department of Industrial and Physical Pharmacy, Purdue University, West Lafayette, Indiana 47907, - - 2013
In this work, a single tablet model and a discrete element method (DEM) computer simulation are developed to obtain the angular circulation speed of tablets in a vibratory tablet coating pan for range of vibration frequencies and amplitudes. The models identify three important dimensionless parameters that influence the speed of ...
Verkooijen Kirsten T - - 2013
Possible interactions among exercise self-identity, social comparison and exercise behaviour were explored in a sample of 417 undergraduate students (Mean age = 21.5, SD = 3.0; 73% female). Two models were examined using self-report data; (1) a mediation model which proposed an association between social comparison and exercise behaviour mediated by exercise self-identity and ...
Kare Pavan - - 2013
Parkinson's disease (PD) is a degenerative disorder of the CNS, characterized by cerebral depletion of dopamine (DA), hence one of the approaches to delay the depletion of DA is to inhibit its oxidative deamination. Monoamine oxidases (MAO) carry out the oxidative deamination of monoamines like DA. These are intracellular enzymes, ...
El-Sisi A A - - 2013
This study aimed at comparing the effects of atorvastatin and vitamin E on erectile dysfunction in patients initially irresponsive to sildenafil, with investigation into the underlying possible mechanisms. Sixty patients were randomly divided into three groups: the atorvastatin group received 80 mg daily, the vitamin E group received 400 IU daily and ...
Pourali Parastoo - - 2013
The purpose of this study was the evaluation of two different temperatures on antibacterial activity of the biosynthesized silver nanoparticles. 38 silver nanoparticles-producing bacteria were isolated from soil and identified. Biosynthesis of silver nanoparticles by these bacteria was verified through visible light spectrophotometry. Two strains were relatively active for production ...
Hwang Jae Chul - - 2013
ABSTRACT: BACKGROUND: Endoscopic sphincterotomy (EST) combined with large-balloon dilation (LBD) has been proposed as an alternative to manage large bile duct stones. However, recent reports indicate that LBD without EST may be safe and effective in this setting. METHODS: One hundred thirty-one patients with large common bile duct (CBD) stones ...
Enjalbert Quentin - - 2013
Targeted mass spectrometry using selected reaction monitoring (SRM) has emerged as an alternative to immunoassays for protein quantification owing to faster development time and higher multiplexing capability. However, the SRM strategy is faced with the high complexity of peptide mixtures after trypsin digestion of whole plasma or the cellular proteome ...
Singh Emma - - 2013
Abstract Adolescents with diabetes must learn to manage their own health plans. Support from family is typically associated with positive self-management outcomes, yet less is known about how healthcare teams can facilitate positive self-management. This study aims to investigate the associations between family and healthcare team support and adolescent emotional, ...
Nugroho Agung - - 2013
The flowers or leaves of Chrysanthemum boreale (Compositae) have been traditionally used as herb tea to reduce anxiety, insomnia, and stress. Sedative and anticonvulsant activities were evaluated in mice using pentobarbital-induced sleeping assay and pentylenetetrazole (PTZ)-induced convulsion assay. The flower extract exhibited more potent activities than the extracts of the ...
Chung Ill-Min - - 2013
Two new compounds lyciumtetraterpenic hexaarabinoside (1) and tetraterpenyl hexaarabinoside (2), along with two known compounds, were isolated from the methanol extract of the fruits of Lycium chinense Miller (Solanaceae), and their structures have been elucidated as 6-(1,1,5-trimethyl-5α-hydroxycyclohexanyl)-6'-(1',1',5'-trimethyl-2'β-hydroxycyclohexanyl)-9,13,9',13'-tetramethyloctadec-7,9,11,13,15,7',9',11',13'-nonene-5α-D-arabinopyranosyl(2a → 1b)-β-D-arabinopyranosyl-(2b → 1c)-β-D-arabinopyranosyl-2'-β-D-arabinopyranosyl-(2d → 1e)-α-D-arabinopyranosyl-(2e → 1f)-α-D-arabinopyranoside (1) and 1(6),11(12),13(14),1'(6'),11'(12'),13'(14')-dodecahydro-β-caroten-4β,4'β-diol-4β-L-arabinopyranosyl-(2a → 1b)-β-L-arabinopyranosyl-(2b → 1c)-β-D-arabinopyranosido-4'β-L-arabinopyranosyl-(2d → 1e)-β-L-arabinopyranosyl-(2e → 1f)-β-D-arabinopyranoside (2) on the basis of spectral data analysis and chemical ...
Su Xiaofang - - 2013
A novel biosensing platform was developed by combining the advantages of electrospun poly(vinyl alcohol) (PVA)/chitosan nanofibers and graphene oxides (GO). Glucose oxidase (GOD) was employed as a model enzyme. By co-electrospinning the solution of PVA, chitosan, GOD and GO, the PVA/chitosan/GOD/GO nanofibers were directly modified on the platinum (Pt) electrode. ...
Davis Ashley - - 2013
A 2 yr old castrated male cat presented to an emergency referral facility for several episodes of gagging, nonproductive coughing, and increased respiratory effort. He was diagnosed with inspiratory stridor and referred to another emergency referral practice for further diagnostics. Three separate, sedated oral examinations, nasal computed tomography (CT), rhinoscopic ...
Banerjee Swagata - - 2013
The development of functional 1,8-naphthalimide derivatives as DNA targeting, anticancer and cellular imaging agents is a fast growing area and has resulted in several such derivatives entering into clinical trials. This review gives an overview of the many discoveries and the progression of the use of 1,8-naphthalimides as such agents ...
Khangura Sajneet K - - 2013
BACKGROUND: Concurrent chemoradiotherapy (CRT) is a potentially curative non-surgical option for locally advanced esophageal cancer, with pathological complete response (CR) ranging from 13 to 49 %. The rate of persistent and recurrent disease within the esophagus remains high at 40-60 %, and treatment of these tumors may improve disease-free survival. The aim ...
Altés Albert - - 2013
Abstract About 15-20% of patients with Hodgkin's lymphoma (HL) treated with ABVD chemotherapy ± radiotherapy still die following relapse or progressive disease. Outcome might be influenced by gene polymorphisms influencing chemotherapy metabolism. We studied 126 patients with HL treated with ABVD regimen. We analyzed glutathione S-transferases (GSTT1, GSTM1 and GSTP1), ...
Lee Kwan Ju - - 2013
BACKGROUND: When surgeons decide to perform lobectomy as the treatment of papillary thyroid carcinomas (PTCs), they must consider the possibility of contralateral cancer. We wanted to determine the incidence of bilateral PTCs (bPTCs) and analyze their characteristics. We also wanted to determine how many patients with bPTC were missed preoperatively. ...
Watanabe Kazushi - - 2013
To determine whether enhanced oxidative stress during pregnancy impairs vascular endothelial function and improves after delivery in preeclamptic women, we measured serum parameters of oxidative stress and endothelial function during pregnancy and 1 month after delivery in women with or without preeclampsia. We evaluated 18 participants with uncomplicated pregnancies, 11 ...
Cheng Cheng - - 2013
A diketopyrrolopyrrole-thiazolothiazole copolymer with a short π-π stacking distance (3.52 Å), due to the introduction of heteroaromatic rings, exhibits a high charge mobility above 3.40 cm(2) V(-1) s(-1) at a relatively gentle annealing temperature.
Garner Sarah R - - 2013
Previous research has demonstrated that participants remember significantly more survival-related information and more information that is processed for its survival relevance. Recent research has also shown that survival materials and processing result in more false memories, ones that are adaptive inasmuch as they prime solutions to insight-based problems. Importantly, false ...
Papavasileiou V - - 2013
PURPOSE: To highlight meningoencephalitis as a transient ischaemic attack (TIA) mimic and suggest clinical clues for differential diagnosis. METHODS: This was an observational study of consecutively admitted patients over a 9.75-year period presenting as TIAs at a stroke unit. RESULTS: A total of 790 patients with TIAs and seven with ...
Tran Tuan Hiep - - 2013
The purpose of this study was to develop a raloxifene-loaded solid dispersion with enhanced dissolution rate and bioavailability via spray-drying technique. Solid dispersions of raloxifene (RXF) were prepared with PVP K30 at weight ratios of 1:4, 1:6 and 1:8 using a spray-drying method, and characterized by differential scanning calorimetry, X-ray ...
Zhang Lin - - 2013
Four new metabolites M-1 [1,2,18,19-tetradehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-2 [1,2,4,21,18,19-hexadehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-3 [1,2,18,19-tetradehydro-4-demethyl-4-formaldehyde-3,17-epoxy-7,20(2H,19H)-cyclovobasan], and M-4 [1,2,4,21,18,19-hexadehydro-4-demethyl-4-oxy-3,17-epoxy-7,20(2H,19H)-cyclovobasan] were isolated from the chloroform extract of koumine incubated with phenobarbital-treated rat liver microsomes. The structures of M-1, M-2, M-3, and M-4 were elucidated by spectroscopic methods including ESI-TOF-MS, 1D, and 2D NMR experiments. The metabolic pathway of ...
Ibrahim Lara - - 2013
Surrogate species are used in standard toxicity tests for the environmental risk assessment of chemicals. Test results are then extrapolated to the situation in the field, which is often associated with a large degree of uncertainty. Since a vulnerable species in the field is not only characterised by its intrinsic ...
Kelly Nichole R - - 2013
OBJECTIVE: To examine the link between binge eating, executive functioning, and behavioral impulsivity. METHOD: Fifty women who reported engaging in weekly binge eating in the absence of regular compensatory behaviors and 66 women with no history of binge eating completed several self-report questionnaires and a brief neuropsychological battery, including the ...
Gil V - - 2013
Background  Pharmacological studies using selective P2Y(1) antagonists, such as MRS2500, and studies with P2Y(1) (-/-) knockout mice have demonstrated that purinergic neuromuscular transmission is mediated by P2Y(1) receptors in the colon. The aim of the present study was to test whether P2Y(1) receptors are involved in purinergic neurotransmission in the ...
Ellenberger Sarah - - 2013
A 3 mo old female Airedale terrier presented with decreased range of motion of the temporomandibular joint (TMJ), which was first recognized at weaning. Computed tomography (CT) revealed abnormal, bilateral ossification of the soft tissues extending from the region of the tympanic bullae to the medial aspect of the angular ...
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