Search Results
Results 701 - 750 of 3031
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Phillips R L - - 2013
Accurate data are required to plan services for managing diabetic ketoacidosis, an important cause of morbidity and mortality in children with Type 1 diabetes. Data can be derived from ad hoc surveys (which provide only a snapshot and can be influenced by response bias), dedicated registers (which involve significant set-up and ...
Surís Alina - - 2013
In this randomized controlled clinical trial, the authors evaluated the effectiveness of cognitive processing therapy (CPT) in the treatment of self-reported and clinician-assessed posttraumatic stress disorder (PTSD) related to military sexual trauma (MST), along with depressive symptoms. Eighty-six veterans (73 female, 13 male) randomly assigned to receive 12 individual sessions ...
Vansteenkiste Johan - - 2013
Abstract BACKGROUND: Prior to the approval of the first erythropoiesis-stimulating agent (ESA) in the early 1990s, red blood cell transfusions were the primary means of treating severe chemotherapy-induced anemia (CIA), with little recourse for those with more mild forms of the condition. The introduction of the ESAs allowed treatment of ...
Checkley Mary Ann MA Center for Cancer Research, National Cancer Institute, Frederick National Laboratory for Cancer Research, Frederick, MD, - - 2013
Incorporation of the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins into assembling particles is crucial for virion infectivity. Genetic and biochemical data indicate that the matrix (MA) domain of Gag and the cytoplasmic tail of the transmembrane glycoprotein gp41 play an important role in coordinating Env incorporation; however, the ...
Baum Rachel - - 2013
Progress towards the sanitation component of Millennium Development Goal (MDG) Target 7c was re-assessed to account for the need to protect communities and the wider population from exposure to human excreta. We classified connections to sewerage as 'improved sanitation' only if the sewage was treated before discharge to the environment. ...
Wu Shuang - - 2013
ABSTRACT: BACKGROUND: One of the fundamental problems in time course gene expression data analysis is to identify genes associatedwith a biological process or a particular stimulus of interest, like a treatment or virus infection. Most of theexisting methods for this problem are designed for data with longitudinal replicates. But in ...
Rahnama Ruyan - - 2013
Local anesthetics are frequently delivered intra-articularly to provide perioperative pain control. Previous studies have shown that the commonly used drugs lidocaine, ropivacaine, and bupivacaine can be toxic to human chondrocytes. The present study was conducted to determine whether the toxic effects of local anesthetics on human chondrocytes also extend to ...
Rizk Guillaume - - 2013
SUMMARY: Counting all the k-mers (substrings of length k) in DNA/RNA sequencing reads is the preliminary step of many bioinformatics applications. However, state of the art k-mer counting methods require that a large data structure resides in memory. Such structure typically grows with the number of distinct k-mers to count.We ...
Gilani Fizza - - 2013
BACKGROUND:Antiplatelet therapy is recommended as part of a strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. However, compliance with these guideline-recommended therapies appears to be less than ideal.OBJECTIVE:To assess the effect of adding pharmacists to primary care teams on initiation of guideline-concordant antiplatelet therapy ...
Rajabbeigi Elham - - 2013
This study was aimed to evaluate antioxidant response of parsley cells to 21 ppm iron and static magnetic field (SMF; 30 mT). The activity of catalase (CAT) and ascorbate peroxidase (APX) and the contents of malonyldialdehyde, iron and ferritin were measured at 6 and 12 h after treatments. Exposure to SMF increased the ...
Vanhoutte Paul M - - 2013
The presence of a healthy epithelium can moderate the contraction of the underlying airway smooth muscle. This is due in part because epithelial cells generate inhibitory messages, whether diffusible substances, electrophysiological signals or both. The epithelium-dependent inhibitory effect can be tonic (basal), synergistic or evoked. Rather than a unique epithelium-derived ...
Bar-Haim Simona - - 2013
Abstract Purpose: To describe Re-Step™, a novel mechatronic shoe system that measures center of pressure (COP) gait parameters and complexity of COP dispersion while walking, and to demonstrate these measurements in healthy controls and individuals with hemiparesis and cerebral palsy (CP) before and after perturbation training. Method: The Re-Step™ was ...
Bendeck Murielle - - 2013
Background Cost of illness (COI) studies are carried out under conditions of uncertainty and with incomplete information. There are concerns regarding their generalisability, accuracy and usability in evidence-informed care. Aims A hybrid methodology is used to estimate the regional costs of depression in Catalonia (Spain) following an integrative approach. Methods ...
Ennis Holly - - 2013
OBJECTIVES: To determine the extent of body image dissatisfaction (BID) in patients with self-reported systemic sclerosis (SSc)-related telangiectases and to identify the demographic, psychological and disease-related correlates of BID within a cross-sectional study. METHODS: Patients with SSc were invited to participate in a questionnaire survey. Each completed the Adjusted Satisfaction ...
Ji Ling - - 2013
The aim of the present study was to investigate the chemical and structural changes in preserved white egg during pickled by vacuum technology. In order to evaluate the changes of preserved egg white during its salted period, sulfhydryl group, disulfide bond contents, and surface hydrophobicity were measured. Fourier transformation infrared ...
Carroll Katherine K Centre for Health Communication, University of Technology, Sydney, Australia. - - 2013
Donor human milk (DHM) is increasingly being used in neonatal intensive care units (NICUs) to achieve exclusive human milk (EHM) feedings in preterm infants. The aim of the study was to determine the cost of DHM to achieve EHM feeding for very preterm infants. The hypothesis was that the cost ...
Obajimi Millicent O - - 2013
ABSTRACT: BACKGROUND: Mammography has been used in developed countries with considerable success but very little is known about this imaging modality in low resource settings. This study examined the level of awareness of mammography and determined factors influencing the level of awareness. METHODS: We conducted a hospital based cross sectional ...
Wanner Sarah J SJ Department of Organismal Biology and Anatomy, The University of Chicago, Chicago, IL 60637, - - 2013
Appropriate localization of neurons within the brain is a crucial component of the establishment of neural circuitry. In the zebrafish hindbrain, the facial branchiomotor neurons (FBMNs) undergo a chain-like tangential migration from their birthplace in rhombomere (r) 4 to their final destination in r6/r7. Here, we report that ablation of ...
Cenoz Manuel García MG Instituto de Salud Pública de Navarra; Pamplona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP); Pamplona, - - 2013
Varicella vaccine effectiveness was evaluated in a case-control study in Navarre, Spain, in 2010-2012. The cases were 54 children aged 15 months to 10 years with a diagnosis of varicella confirmed by polymerase-chain-reaction. Each case was matched with eight controls by pediatric practice, district of residence and date of birth. ...
Iba Michiyo - - 2013
Tauopathies, including Alzheimer's disease (AD) and frontotemporal lobar degeneration with tau pathologies, are neurodegenerative diseases characterized by neurofibrillary tangles (NFTs) comprising filamentous tau protein. Although emerging evidence suggests that tau pathology may be transmitted, we demonstrate here that synthetic tau fibrils are sufficient to transmit tau inclusions in a mouse ...
Ritz Thomas - - 2013
ObjectiveAnxiety and panic are associated with the experience of a range of bodily symptoms, in particular unpleasant breathing sensations (dyspnea). Respiratory theories of panic disorder have focused on disturbances in blood gas regulation, but respiratory muscle tension as a source of dyspnea has not been considered. We therefore examined the ...
Volberg Vitaly - - 2013
What is already known about this subject Mexican-American children are at particularly high risk of obesity. Features of the perinatal environment, including maternal nutrition, anthropometry, glucose tolerance and growth rate during infancy are implicated in programming of obesity in the offspring. What this study adds Greater rate of weight or ...
Nielsen Hans Jørgen - - 2013
Abstract Objective. Results from monitoring studies using biomarkers in blood samples aiming at early detection of recurrent colorectal cancer (CRC) are presently evaluated. However, some serological biomarker levels are influenced by the surgical trauma, which may complicate translation of the levels in relation to recurrence. The primary purpose of the ...
Homan Kristin J - - 2013
Positive body image is defined as healthy body-related attitudes that go beyond the absence of distressful symptoms. A warm and secure relationship with an important other person has been linked with attitudes of acceptance and appreciation toward one's body as well as adaptive eating patterns. This study tested whether a ...
Jaarsma Caroline - - 2013
ABSTRACT: BACKGROUND: Although echocardiography is used as a first line imaging modality, its accuracy to detect acute and chronic myocardial infarction (MI) in relation to infarct characteristics as assessed with late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR) is not well described. METHODS: One-hundred-forty-one echocardiograms performed in 88 first acute ST-elevation ...
Zhang Guizhong G Institute of Immunology, Shandong University School of Medicine, Ji'nan, - - 2013
Phenotypic switching of vascular smooth muscle cells (VSMCs) is known to play a key role in the development of atherosclerosis. However, the mechanisms that mediate VSMC phenotypic switching are unclear. We report here that TIPE2, the tumor necrosis factor (TNF) α-induced protein 8-like 2 (TNFAIP8L2), plays an atheroprotective role by ...
James Neil - - 2013
This article reports the findings of a literature review of research that has explored the support experiences of family carers of a person with an intellectual disability who displays challenging behaviour and/or has a mental health problem. The purpose of this review is to provide an overview of the reported ...
Dougherty Kelly A KA Center for Learning and Memory, The University of Texas at Austin, Austin, TX 78712, USA. - - 2013
The rodent hippocampus can be divided into dorsal (DHC) and ventral (VHC) domains on the basis of behavioral, anatomical, and biochemical differences. Recently, we reported that CA1 pyramidal neurons from the VHC were intrinsically more excitable than DHC neurons, but the specific ionic conductances contributing to this difference were not ...
Ruiz Stacey - - 2013
Oxidative stress and inflammation are mediators in the development and progression of chronic kidney disease (CKD) and its complications, and they are inseparably linked as each begets and amplifies the other. CKD-associated oxidative stress is due to increased production of reactive oxygen species (ROS) and diminished antioxidant capacity. The latter ...
Langemeier Jörg J Institute for Virology, Hannover Medical School, Hannover, - - 2013
The spliceosomal component U1snRNP commits pre-mRNAs to the splicing pathway. Recently, a nuclear RNA surveillance function has been ascribed to U1, namely the suppression of intronic polyadenylation sites. This surveillance holds regulatory potential as it alters the 3' ends of certain receptor tyrosine kinase mRNAs. However, suppression of 3' end ...
Varley Katherine E KE HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, - - 2013
As studies of DNA methylation increase in scope, it has become evident that methylation has a complex relationship with gene expression, plays an important role in defining cell types, and is disrupted in many diseases. We describe large-scale single-base resolution DNA methylation profiling on a diverse collection of 82 human ...
Crawford Robert - - 2013
CAP-turing the moment: A cage made from DNA can be used to encapsulate a transcription factor (catabolite activator protein, CAP; see figure) without covalent attachment. CAP is shown to stably bind inside the DNA cage at a 1:1 ratio by bending one edge to accommodate the protein. Single-molecule fluorescence measurements ...
Geng Qiang - - 2013
Abstract Background: Patients with mixed dyslipidemia can benefit from the combination of fenofibric acid (FA) with statins, but concerns about adverse events make physicians reluctant to prescribe the combination therapy. Objective: In the present study, we performed a meta-analysis of randomized controlled trials (RCTs) to assess the efficacy and adverse ...
Wadsworth Martha E - - 2013
This study tests key tenets of the Adaptation to Poverty-related Stress Model. This model (Wadsworth, Raviv, Santiago, & Etter, 2011 ) builds on Conger and Elder's family stress model by proposing that primary control coping and secondary control coping can help reduce the negative effects of economic strain on parental ...
Zeller Mario - - 2013
PURPOSE: To optimize the spatial response function (SRF) while maintaining optimal signal to noise ratio (SNR) in T(2) weighted turbo spin echo (TSE) imaging by prospective density weighting. MATERIALS AND METHODS: Density weighting optimizes the SRF by sampling the k-space with variable density without the need of retrospective filtering, which ...
Brégnard Christelle - - 2013
Nef is a human immunodeficiency virus type 1 (HIV-1) auxiliary protein that plays an important role in virus replication and the onset of acquired immunodeficiency. Although known functions of Nef might explain its contribution to HIV-1-associated pathogenesis, how Nef increases virus infectivity is still an open question. In vitro, Nef-deleted ...
Kim Seung-Ju - - 2013
Use of an autogenous bone plug for the tibial tunnel in anterior cruciate ligament (ACL) reconstruction has been advocated to achieve tendon-to-bone healing. Our hypothesis was that use of an autogenous bone plug, instead of a bioabsorbable interference screw, for secondary fixation of tendon allograft to the proximal part of ...
Fellini Laetitia - - 2013
Episodic memory is relevant for auto-consciousness in humans. In nonhuman animals, episodic-like memory is defined when the "what-where-when" content of a unique event forms an integrated cognitive representation that is then deployed during memory retrieval. Here, we aimed at testing episodic-like memories of mice under experimental conditions that allow the ...
Xie Boya - - 2013
MOTIVATION: Research interests in microRNAs have increased rapidly in the past decade. Many studies have showed that microRNAs have close relationships with various human cancers, and they potentially could be used as cancer indicators in diagnosis or as a suppressor for treatment purposes. There are several databases that contain microRNA-cancer ...
Kaufman Kenneth R - - 2013
OBJECTIVE:To describe what we believe is the first reported case of synergistic gynecomastia during treatment of depressive and anxiety disorders when sertraline was added to a stable medication regimen including duloxetine, rosuvastatin, and amlodipine.CASE SUMMARY:A 67-year-old male with major depression, dysthymia, obsessive-compulsive disorder, social anxiety, hypertension, diabetes, and hyperlipidemia presented ...
Hashem Mohamed G - - 2013
BACKGROUND:Aromatase inhibitors function by suppressing estrogen biosynthesis in peripheral tissues. The resulting estrogen deprivation is considered the underlying cause for aromatase inhibitor-induced arthralgia, which affects patients' quality of life and may affect their persistence to aromatase inhibitor therapy. The effect of concurrent treatment with aromatase inhibitors and prescription antiarthralgia pharmacotherapy ...
Adeoye Olayemi O OO Division of Physiology, Center for Perinatal Biology, Loma Linda University School of Medicine, Loma Linda, CA 92350, - - 2013
Recent studies suggest that vascular endothelial growth factor (VEGF) can modulate smooth muscle phenotype and, consequently, the composition and function of arteries upstream from the microcirculation, where angiogenesis occurs. Given that hypoxia potently induces VEGF, the present study explores the hypothesis that, in fetal arteries, VEGF contributes to hypoxic vascular ...
Urish K L - - 2013
Robotic, high-throughput microscopy is a powerful tool for small molecule screening and classifying cell phenotype, proteomic and genomic data. An important hurdle in the field is the automated classification and visualization of results collected from a data set of tens of thousands of images. We present a method that approaches ...
Mara Michael W - - 2013
The effects of structural constraints on the metal-to-ligand-charge-transfer (MLCT) excited state structural dynamics of cuprous bis-2,9-diphenyl-phenanthroline ([Cu(I)(dpp)2]+) in both coordinating acetonitrile and non-coordinating toluene were studied using X-ray transient absorption (XTA) spectroscopy and density functional theory (DFT) calculations. The phenyl groups attached onto the phenanthroline ligands not only effectively shield ...
Martins Derliane Ribeiro - - 2013
This work evaluated physicochemical parameters of Golden papaya stored under refrigeration in controlled atmospheres. The fruits were kept at 13 °C in chambers containing either 3 or 6% O(2) combined with 6%, 10% or 15% CO(2). Moreover, a normal atmosphere was produced with 20.8% O(2) and 0.03% CO(2) with ethylene ...
Kuhlman Thomas S - - 2013
Internal conversion: The energy difference between the Franck-Condon and equilibrium geometries and the vibrational frequency of one or a few modes determine the relative importance of adiabatic and nonadiabatic dynamics and thus the rate of electronic energy dissipation. In the cycloketones, variations in these quantities lead to a difference in ...
Ainsbury Elizabeth A - - 2013
The Poisson distribution is the most widely recognised and commonly used distribution for cytogenetic radiation biodosimetry. However, it is recognised that, due to the complexity of radiation exposure cases, other distributions may be more properly applied. Here, the Poisson, gamma, negative binomial, beta, Neyman type-A and Hermite distributions are compared ...
Wan Mimi M Department of Immunobiology, Yale University, New Haven, CT 06520, - - 2013
Environmental factors can stably perturb the epigenome of exposed individuals and even that of their offspring, but the pleiotropic effects of these factors have posed a challenge for understanding the determinants of mitotic or transgenerational inheritance of the epigenetic perturbation. To tackle this problem, we manipulated the epigenetic states of ...
Fraser Lena G - - 2013
ABSTRACT: BACKGROUND: Red colour in kiwifruit results from the presence of anthocyanin pigments. Their expression, however, is complex, and varies among genotypes, species, tissues and environments. An understanding of the biosynthesis, physiology and genetics of the anthocyanins involved, and the control of their expression in different tissues, is required. A ...
Toossi Nader - - 2013
The use of cementless acetabular components in total hip arthroplasty has gained popularity over the past decade. Most total hip arthroplasties being performed in North America currently use cementless acetabular components. The objective of this systematic review and meta-analysis was to compare the survivorship and revision rate of cemented and ...
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