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Results 501 - 550 of 3031
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Stange Ulrike - - 2013
Abstract The taste of oral dosage forms is an important argument regarding patient's compliance and acceptability. For this reason, it is often necessary to mask an undesirable and unpleasant taste of an active pharmaceutical ingredient. The purpose of this study was to mask the taste of naproxen sodium by a ...
Zhou Lisha - - 2013
Stable Cu(2)O nanocrystals of around 3 nm were uniformly and densely grown on functionalized graphene sheets (FGS), which act as molecular templates instead of surfactants for controlled nucleation; the distribution density of nanocrystals can be easily controlled by FGS with different C/O ratios. The nanocomposite displays improved stability of the ...
Li Na - - 2013
A resorcinarene-based macrocyclic ligand functionalized with alanine and undecyl groups (AUA) was synthesized and applied to ion chromatographic separations. The selectivity and separation of transition metal ions on a column packed with AUA adsorbed onto 55% cross-linked styrene-divinylbenzene resin are presented. The upper and lower rims of the resorcinarene were ...
Ritter Merrill A - - 2013
Implant survival after total knee arthroplasty has historically been dependent on postoperative knee alignment, although failure may occur when alignment is correct. Preoperative knee alignment has not been thoroughly evaluated as a possible risk factor for implant failure after arthroplasty. The purpose of this study was to analyze the effect ...
Griguoli Marilena - - 2013
In the hippocampus, at excitatory synapses between principal cell and oriens/alveus (O/A) interneurons, a particular form of NMDA-independent long-term synaptic plasticity (LTP) has been described (Lamsa et al., 2007). This type of LTP occurs when presynaptic activation coincides with postsynaptic hyperpolarization. For this reason it has been named "anti-Hebbian" to ...
Luan Hongge - - 2013
The cerebellar interpositus nucleus (IN) contributes to controlling voluntary limb movements. We hypothesized that the vestibular signals within the IN might be transformed into coordinates describing the body's movement, appropriate for controlling limb movement. We tested this hypothesis by recording from IN neurons in alert squirrel monkeys during vestibular and ...
Smale Dan A DA Marine Biological Association of the United Kingdom, The Laboratory, Citadel Hill, Plymouth PL1 2PB, - - 2013
Species distributions have shifted in response to global warming in all major ecosystems on the Earth. Despite cogent evidence for these changes, the underlying mechanisms are poorly understood and currently imply gradual shifts. Yet there is an increasing appreciation of the role of discrete events in driving ecological change. We ...
Liu Wei - - 2013
ABSTRACT: INTRODUCTION: Neural stem cell transplantation is a promising tool for the restoration of the enteric nervous system in a variety of motility disorders. However, limited cell viability after transplantation has restricted its regenerative capacity. The aim of this study was to evaluate the effect of transplantation of neuroepithelial stem ...
Araki Yoshiaki - - 2013
The concept of band engineering dilute nitride semiconductors into nanowires is introduced. Using plasma-assisted molecular beam epitaxy, dilute nitride GaAsN/GaAs heterostructure nanowires are grown on silicon (111) substrates. Growth of the nanowires under high As overpressure results in a regular wire diameter of 350 nm with a length exceeding 3 μm. The ...
Barcellos-Hoff Mary Helen - - 2013
What dictates the prevalence of certain types of breast cancer, which are classified by markers, particularly estrogen receptor (ER), expression profiles such as basal or luminal, and genetic alterations such as HER2 amplification, in particular populations is not well understood. It is increasingly evident that microenvironment disruption is highly intertwined ...
Preyat Nicolas - - 2013
Lysine deacetylation by the NAD(+)-dependent family of sirtuins has been recognized as an important post-translational modification regulating a wide range of cellular processes. These lysine deacetylases have attracted much interest based on their ability to promote survival in response to stress. Sirtuins require NAD(+) for their enzymatic activity, suggesting that ...
Haenen Daniëlle - - 2013
Resistant starch (RS) is highly fermentable by microbiota in the colon, resulting in the production of SCFAs. RS is thought to mediate a large proportion of its health benefits, including increased satiety, through the actions of SCFAs. The aim of this study was to investigate the effects of a diet ...
Stagg Charlotte J CJ Centre for Functional Magnetic Resonance of the Brain, University of Oxford, - - 2013
To demonstrate the sensitivity of a recently developed whole-brain magnetic resonance spectroscopic imaging (MRSI) sequence to cerebral pathology and disability in amyotrophic lateral sclerosis (ALS), and compare with measures derived from diffusion tensor imaging. Whole-brain MRSI and diffusion tensor imaging were undertaken in 13 patients and 14 age-similar healthy controls. ...
Goncalves Emanuel J V - - 2013
ABSTRACT: BACKGROUND: A standard graphical notation is essential to facilitate exchange of network representations of biologicalprocesses. Towards this end, the Systems Biology Graphical Notation (SBGN) has been proposed, and it isalready supported by a number of tools. However, support for SBGN in Cytoscape, one of the most widelyused platforms in ...
Magdeburg R - - 2013
Acute appendicitis is still one of the most common abdominal emergencies necessitating operative treatment. For the past century, the conventional management of appendicitis has been open appendectomy. Since the introduction of laparoscopic appendectomy, it has been performed with increased frequency. Clinical trials evaluating outcomes comparing open appendectomy with laparoscopic appendectomy ...
Gallant-Behm Corrie L - - 2013
ΔNp63α is a potent oncogene in squamous cell carcinomas (SCCs) and a pro-proliferative factor expressed by basal epithelial cells. ΔNp63α functions both as a transcriptional repressor and activator, but it is not clear how these activities contribute to its oncogenic potential. ΔNp63α was proposed to function as a dominant negative ...
Lech Maciej - - 2013
Ischemia-reperfusion activates innate immunity and sterile inflammation, resulting in acute kidney injury. Since pentraxin 3 (PTX3) regulates multiple aspects of innate immunity and tissue inflammation, we tested whether PTX3 would be involved in renal ischemia-reperfusion injury. Renal pedicle clamping increased PTX3 serum levels, as well as PTX3 expression, inside the ...
Llor Carl - - 2013
BACKGROUND: The aim of this study was to describe the antibiotic prescribing rate in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), to analyse predictors for antibiotic prescribing and to explore the influence of the use C-reactive protein (CRP) rapid test. METHODS: A cross-sectional study was carried out ...
Talwar Sudha S Department of Craniofacial Biology and Center for Oral Health Research, College of Dental Medicine, Medical University of South Carolina, Charleston, SC, - - 2013
CELF1 RNA-binding protein, otherwise called CUGBP1, associates and coordinates the degradation of GU-rich element (GRE) containing mRNA's encoding factors important for cell growth, migration and apoptosis. Although many substrates of CELF1 have been identified, the biological significance of CELF1-mediated mRNA decay remains unclear. As the processes modulated by CELF1 are ...
Bustinduy Amaya L AL CTID Building, Liverpool School of Tropical Medicine, Liverpool, UK. - - 2013
We measured prevalence of Schistosoma haematobium, Wuchereria bancrofti, Plasmodium falciparum, hookworm, and other geohelminths among school-aged children in four endemic villages in Kwale County, Kenya and explored the relationship between multiparasite burden, undernutrition, and anemia. In 2009-2010 surveys, cross-sectional data were obtained for 2,030 children 5-18 years old. Infections were ...
Meyer-Rochow V Benno - - 2013
ABSTRACT: In terms of scientific activities generally and ethnobiological pursuits in particular, North Korea, officially known as the Democratic People's Republic of Korea, is an almost blank entity on the quilt of global research. During a sabbatical semester at Pyongyang University of Science and Technology the author used this opportunity ...
Buyuktemiz Muhammed - - 2013
Low lying electronic states of the highly fluorescent BODIPY (1) and its non-emissive cousin dipyrrin (2) were investigated by state of the art quantum chemical methods. The opposed luminescence of 1 and 2 are explained by discovering distinct structural and energetic features for the intersection of the ground and first ...
Maarschalk-Ellerbroek L J - - 2013
Gastrointestinal symptoms are common in patients with common variable immunodeficiency disorders (CVID) and less frequent in X-linked agammaglobulinemia (XLA) although the exact prevalence is not well established. In this study, endoscopic screening was performed in 30 patients with CVID and four patients with XLA. Endoscopic and/or histological abnormalities were detected ...
Tsuji Hiroyuki - - 2013
Florigen, a protein encoded by the FLOWERING LOCUS T (FT) in Arabidopsis and Heading date 3a (Hd3a) in rice, is the universal flowering hormone in plants. Florigen is transported from leaves to the shoot apical meristem and initiates floral evocation. In shoot apical cells, conserved cytoplasmic 14-3-3 proteins act as ...
Fayyaz Jabeen - - 2013
ABSTRACT: BACKGROUND: A patient left without being seen is a well-recognized indicator of Emergency Department overcrowding. The aim of this study was to define the characteristics of LWBS patients, their rates and associated factors from a tertiary care hospital of Pakistan. METHODS: A retrospective patient record review was undertaken. All ...
Ross-Thriepland Douglas - - 2013
The NS5A protein of hepatitis C virus (HCV) plays roles in both virus genome replication and the assembly of infectious virus particles. NS5A comprises three domains, separated by low-complexity sequences. Whilst the function of domain I appears to be predominantly involved with genome replication, the roles of domains II and ...
Yin DeLu Tyler DT University of Minnesota, Department of Biochemistry, Molecular Biology & Biophysics, and The Biotechnology Institute, 1479 Gortner Avenue, Saint Paul, MN 55108, - - 2013
Some serine hydrolases also catalyze a promiscuous reaction--reversible perhydrolysis of carboxylic acids to make peroxycarboxylic acids. Five X-ray crystal structures of these carboxylic acid perhydrolases show a proline in the oxyanion loop. Here, we test whether this proline is essential for high perhydrolysis activity using Pseudomonas fluorescens esterase (PFE). The ...
Del Amo J - - 2013
We estimated the effect of sexual behavior, age and immunodeficiency on the number of High-Risk Human-Papillomavirus (HR-HPV) in the anal canal among HIV-positive men who have sex with men (MSM). Anal samples were genotyped with Linear Array and risk factors were investigated with Poisson regression. Of 586 MSM, 69% were ...
Jelodar Gholamali - - 2013
Radio frequency wave (RFW) generated by base transceiver station (BTS) has been reported to make deleterious effects on reproduction, possibly through oxidative stress. This study was conducted to evaluate the effect of RFW generated by BTS on oxidative stress in testis and the prophylactic effect of vitamin C by measuring ...
Johnson Kameka Latoya - - 2013
Agrobacterium vitis, the causal agent of grape crown gall, can have severe economic effects on grape production. The bacterium survives systemically in vines and therefore is disseminated in propagation material. We developed an assay, for use in indexing programs, that is efficient and sensitive for detecting A. vitis in grape ...
Khodabakhshi G G Department of Computer Science, University of Sheffield, Sheffield, - - 2013
Tendons are tough fibrous tissues that facilitate skeletal movement by transferring muscular force to bone. Studies into the effects of mechanical stress on tendons have shown that these can either accelerate healing or cause tendon injuries depending on the load applied. It is known that local strain magnitude and direction ...
Zhang Shixiong - - 2013
We demonstrate all-electrical spin injection, transport and detection in heavily n-type doped Si nanowires using ferromagnetic Co/Al(2)O(3) tunnel barrier contacts. Analysis of both local and non-local spin valve signals at 4 K on the same nanowire device using a standard spin-transport model suggests that high spin injection efficiency (up to ...
Falaise Clément C Unité de Catalyse et Chimie du Solide (UCCS), UMR CNRS 8181, Université de Lille Nord de France, USTL-ENSCL, Bat C7, BP 90108, 59652 Villeneuve d'Ascq, - - 2013
Four metal-organic frameworks (MOF) with tetravalent uranium have been solvothermally synthesized by treating UCl4 with rigid dicarboxylate linkers in N,N-dimethylfomamide (DMF). The use of the ditopic ligands 4,4'-biphenyldicarboxylate (1), 2,6-naphthalenedicarboxylate (2), terephthalate (3), and fumarate (4) resulted in the formation of three-dimensional networks based on the hexanuclear uranium-centered motif [U6O4(OH)4(H2O)6]. ...
Link Jason M - - 2013
Comment on: Link JM, et al. Proc Natl Acad Sci USA 2012; 109:19685-90.
Porter Aaron T AT Department of Statistics, University of Missouri, Columbia, Missouri 65211, USA. - - 2013
Most current Bayesian SEIR (Susceptible, Exposed, Infectious, Removed (or Recovered)) models either use exponentially distributed latent and infectious periods, allow for a single distribution on the latent and infectious period, or make strong assumptions regarding the quantity of information available regarding time distributions, particularly the time spent in the exposed ...
O'Brien Megan K MK Department of Mechanical Engineering, University of Colorado Boulder, Boulder, CO, - - 2013
An intriguing finding in motor control studies is the marked effect of risk on movement decision making. However, there are inconsistent reports of risk-sensitivity across different movements and tasks, with both risk-seeking and risk-averse behavior observed. This raises the question of whether risk-sensitivity in movement decision making is context dependent ...
Wheeler David C - - 2013
The Kidney Disease: Improving Global Outcomes Clinical Practice Guideline for management of blood pressure (BP) in chronic kidney disease (CKD) supersedes the 2004 Kidney Disease Quality Outcomes Initiative document on this topic. The new guideline has been designed to assist clinical decision making in patients with CKD who are not ...
Ford Kevin A - - 2013
Electrostatic potential (ESP) is a useful physicochemical property of a molecule that provides insights into inter- and intra-molecular associations, as well as prediction of likely sites of electrophilic and nucleophilic metabolic attack. Knowledge of sites of metabolic attack is of parameter importance in DMPK research since drugs frequently fail in ...
Jiang Shu-Ye - - 2013
ABSTRACT: BACKGROUND: Biological scientists have long sought after understanding how genes and their structural/functional changes contribute to morphological diversity. Though both grain (BTx623) and sweet (Keller) sorghum lines originated from the same species Sorghum bicolor L., they exhibit obvious phenotypic variations. However, the genome re-sequencing data revealed that they exhibited ...
Suga Keishi - - 2013
The effect of cationic liposomes (CLs) on mRNA conformation and translation was studied, focusing on membrane heterogeneity. CLs, composed of 1,2-dioleoyl-sn-glycerol-3-phosphocholine/1,2-dioleoyl-3-timethylammonium propane (DOPC/DOTAP) and DOPC/3β-[N-(N',N'-dimethylaminoethane)-carbamoyl]cholesterol (DOPC/DC-Ch), inhibited mRNA translation in an Escherichia coli cell-free translation system. Analysis of the membrane fluidity and polarity indicated a heterogeneous DOPC/DC-Ch (70/30) membrane, while ...
Khare Reeti - - 2013
Adenovirus serotype 5 (Ad5) naturally infects the liver after intravenous injection, making it a candidate for hepatocyte-directed gene transfer. While Ad5 can be efficient, most of the dose is destroyed by liver Kupffer cells before it can reach hepatocytes. In contrast, Ad5 bearing the hexon from Ad6 (Ad5/6) evades Kupffer ...
Steudel Ralf - - 2013
The sodium-sulfur (NAS) battery is a candidate for energy storage and load leveling in power systems, by using the reversible reduction of elemental sulfur by sodium metal to give a liquid mixture of polysulfides (Na(2) S(n) ) at approximately 320 °C. We investigated a large number of reactions possibly occurring in ...
Lenox C E - - 2013
Fish oil omega-3 fatty acids, mainly eicosapentaenoic acid and docosahexaenoic acid, are used in the management of several diseases in companion animal medicine, many of which are inflammatory in nature. This review describes metabolic differences among omega-3 fatty acids and outlines potential adverse effects that may occur with their supplementation ...
Polak Michal M Department of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221-0006, USA. - - 2013
Developmental selection, the non-random elimination of offspring during development, is hypothesized to alter the opportunity for selection on a given trait at later stages of the life cycle. Here, we provide a direct demonstration of developmental selection against developmental instability, assessed as the incidence of minor, discrete phenotypic abnormalities in ...
Vinall Jillian - - 2013
Slower postnatal growth is an important predictor of adverse neurodevelopmental outcomes in infants born preterm. However, the relationship between postnatal growth and cortical development remains largely unknown. Therefore, we examined the association between neonatal growth and diffusion tensor imaging measures of microstructural cortical development in infants born very preterm. Participants ...
Lloret-Linares Célia - - 2013
OBJECTIVE:To report a case of an overweight man with lymph node tuberculosis due to Mycobacterium bovis, a part of the Mycobacterium tuberculosis complex, treated with fixed-dose combination (FDC) chemotherapy.CASE REPORT:Following guidelines, according to the patient's weight (92 kg), we prescribed the maximum recommended doses of isoniazid-rifampin-pyrazinamide FDC. It led initially ...
Kirk Deepa - - 2013
OBJECTIVE:To report 2 cases of spuriously elevated testosterone measurements caused by contamination of blood samples by testosterone gel applied near the phlebotomy site.CASE SUMMARIES:A 21-year-old male with primary hypogonadism and a 67-year-old male with secondary hypogonadism were prescribed standard replacement doses of testosterone gel. The patients' symptoms improved without adverse ...
Baranowska Irena - - 2013
This paper reports the development of a method for simultaneously determining five preservatives in cosmetics, cleaning agents and pharmaceuticals by fast liquid chromatography. Methylisothiazolinone, methylchloroisothiazolinone, benzyl alcohol, sodium benzoate and methylparaben were separated on a Chromolith Fast Gradient reversed-phase 18e column using gradient elution with acetonitrile and a 0.1% aqueous ...
Schachman Kathleen - - 2013
OBJECTIVE: To estimate the prevalence of postpartum depressive symptoms in a sample of military wives, and to provide a comparative descriptive analysis of demographic, risk and protective factors. DESIGN: A comparative descriptive design. SETTING: A large military base in southeastern United States. PARTICIPANTS: Military wives (N = 71) who had given birth ...
Gagnon Kenneth B KB Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, Saskatchewan, - - 2013
Among the over 300 members of the solute carrier (SLC) group of integral plasma membrane transport proteins are the nine electroneutral cation-chloride cotransporters belonging to the SLC12 gene family. Seven of these transporters have been functionally described as coupling the electrically silent movement of chloride with sodium and/or potassium. Although ...
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