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Petrie Casey N - - 2013
Elevating levels of nerve growth factor (NGF) can have pronounced effects on the survival and maintenance of distinct populations of neurons. We have generated a line of transgenic mice in which NGF is expressed under the control of the smooth muscle α-actin promoter. These transgenic mice have augmented levels of ...
Pereira-Cunha Fernanda G - - 2013
BACKGROUND: Umbilical cord blood (UCB) is a good source of hematopoietic stem cells for transplantation and cell therapy. In 2006, the Brazilian Public Network of Cord Blood Banks was founded; however, because our country is large, logistic problems could hamper the collection of numerous samples. Our aim was to evaluate ...
Shetty Geetha A - - 2013
Hippocampal neurogenesis, important for memory and mood function, wanes greatly in old age. Studies in rat models have implied that this decrease is not due to loss of neural stem cells (NSCs) in the subgranular zone of the dentate gyrus (DG) but rather due to an increased quiescence of NSCs. ...
Falkmer Torbjörn - - 2013
At present, 'gold standard' diagnosis of autism spectrum disorders (ASD) is a lengthy and time consuming process that requires suitably qualified multi-disciplinary team (MDT) personnel to assess behavioural, historical, and parent-report information to determine a diagnosis. A number of different tools have been developed to assist in determination. To optimise ...
Givi Babak - - 2013
BACKGROUND: A variety of tumors arise in or extend to the infratemporal fossa. We investigated the outcome of surgical management of these tumors. METHODS: We conducted a retrospective review of a craniofacial approach to resection of infratemporal fossa tumors from 1992 to 2008 in a cancer center. RESULTS: Forty-three patients ...
Pikkel Joseph - - 2013
BACKGROUND: To investigate a possible structural difference in the retina of hydroxychloroquine (Plaquenil)-treated patients as an explanation for the protective effect of this medication against age-related macular degeneration (AMD). METHODS: In this retrospective study, we compared the mean thickness of the retinal outer band (consisting of the Bruch's membrane and ...
Dinolfo Caterina - - 2013
This study examined the relations between interpretive understanding, sympathy, and moral emotion attribution (MEA) in the prediction of oppositional defiant disorder (ODD) symptomatology in an ethnically diverse sample of 128 4- and 8-year-old children (49 % girls). Caregivers rated the children's ODD symptoms. Interpretive understanding was assessed using an advanced theory-of-mind ...
Pines Amos - - 2013
ABSTRACT For many years the preliminary results of both arms of the Women's Health Initiative (WHI) were translated into very cautious, even negative recommendations in regard to the use of postmenopausal hormones. Despite the fact that further analyses from the WHI study, as well as data from other studies should ...
Bacchi Ataís - - 2013
Abstract Objective. This study evaluated the influence of framework material and vertical misfit on stress created in an implant-supported partial prosthesis under load application. Materials and methods. The posterior part of a severely reabsorbed jaw with a fixed partial prosthesis above two osseointegrated titanium implants at the place of the ...
OleĊ„ska Ewa - - 2013
The aim of this study was to identify heavy metal detoxification system in Rhizobium leguminosarum bv. trifolii isolated from Trifolium repens inhabiting old (70-100 years) Zn-Pb waste heaps in Poland by PCR reaction with czcD1 and czcD2 primers. By sequence analysis, four different genotypes of obtained amplicons were identified among eight ...
Eguchi Hidetoshi - - 2013
Background/Aims: In order to improve the poor prognosis of pancreatic cancer, a combination therapy consisting of preoperative chemoradiotherapy, surgery and postoperative chemotherapy may be an ideal strategy; nevertheless, the influence of preoperative therapy to postoperative therapy is not investigated. Methodology: Thirty patients with resectable pancreatic ductal adenocarcinoma were enrolled. A ...
Werner Hauke B - - 2013
The formation of central nervous system myelin by oligodendrocytes requires sterol synthesis and is associated with a significant enrichment of cholesterol in the myelin membrane. However, it is unknown how oligodendrocytes concentrate cholesterol above the level found in nonmyelin membranes. Here, we demonstrate a critical role for proteolipids in cholesterol ...
Prabhu Somnath J - - 2013
BACKGROUND: Percutaneous arterial closure devices have increasingly entered clinical practice to assist in achieving femoral arterial access site hemostasis. Prior studies have demonstrated the safety and efficacy of several arterial closure devices in adults. OBJECTIVE: To evaluate the efficacy of using an arterial closure device in children. MATERIALS AND METHODS: ...
Tunca Berrin - - 2013
PURPOSE: Due to ethnic, genetic and environmental factors, the clinical and molecular characteristics of Turkish colorectal cancer (CRC) patients are different from those of Western populations. The aim of this study was to clarify the relevant alterations of gene expression associated with colorectal carcinogenesis in early-onset patients and to identify ...
Jones Patricia L - - 2013
The mating calls of male túngara frogs, Physalaemus pustulosus, attract intended (conspecific females) and unintended (eavesdropping predators and parasites) receivers. The calls are complex, having two components: a frequency-modulated "whine" followed by 0-7 harmonic bursts or "chucks". The whine is necessary and sufficient to elicit phonotaxis from females and the ...
Min Hong Ki - - 2013
ABSTRACT: BACKGROUND: Rifampin is one of the most important drugs in first-line therapies for tuberculosis. The renal toxicity of rifampin has been reported sporadically and acute tubulointerstitial nephritis (ATIN) is a frequent histological finding. We describe for the first time a case of ATIN and Fanconi syndrome presenting as hypokalemic ...
Susha Andrei S - - 2013
We present results of a comparative study of colloidal anatase titanium oxide nanorods and extremely thin atomic wires of systematically decreasing (2.6 nm down to 0.5 nm) diameter in terms of their optical absorption as well as steady-state and time-resolved photoluminescence. Steady-state photoluminescence spectra of the titania samples show three ...
Muhammad Hayat - - 2013
Introduction: Hyaline articular cartilage is the connective tissue responsible for frictionless joint movement. Its degeneration ultimately results in complete loss of joint function in the late stages of osteoarthritis. Intrinsic repair is compromised, and cartilage tissue regeneration is difficult. However, new options are available to repair cartilage tissue by applying ...
Boesgaard Kristine S - - 2013
There is an ongoing debate on how to correct leaf gas-exchange measurements for the unavoidable diffusion leakage that occurs when measurements are done in non-ambient CO(2) -concentrations. In this study we present a theory on how the CO(2) diffusion gradient over the gasket is affected by leaf mediated pores (LMP) ...
Kinabo G D - - 2013
OBJECTIVES: To estimate the prevalence of nasopharyngeal bacterial colonisation (NPBC) patterns in young Tanzanian HIV-exposed infants and to analyse the influence of maternal NPBC and of the infant's HIV status on the NPBC pattern. METHODS: Longitudinal cohort study of neonates born to HIV-infected mothers visiting Kilimanjaro Christian Medical Centre, Tanzania, ...
Zeng Huahui - - 2013
[(99m)Tc(CO)(3)](+)-6-[N-(2-dipicolyl)amino]hexanoic acid () and [(99m)Tc(CO)(3)](+)-11-[N-(2-dipicolyl)amino]undecanoic acid () were prepared by incorporating [(99m)Tc-(CO)(3)](+) into 6-[N-(2-dipicolyl)amino]hexanoic acid and 11-[N-(2-dipicolyl)amino]undecanoic acid, respectively. The overall radiochemical yield of and was from 79.7% to 91.3% and radiochemical purity after HPLC purification was more than 94%. The resulting complexes were found to be chemically stable when ...
Ronay Valerie - - 2013
Abstract Objective. To evaluate the capability of soft laser light to penetrate blood, serum, gingival connective tissue and pure collagen type I. Materials and methods. A 1:1 mixture of methylene blue (MB) and diphenylisobenzofuran (DPBF) was irradiated for 60 s with a diode laser (670 nm, 0.3 W) through blood, ...
Chung Woojung - - 2013
In the present paper, we ascertain two novel findings on chiral-selective binding / separating of single-walled carbon nanotubes (SWNTs) with a non-aromatic polymer, poly(dialkylsilane)(PSi). PSi is a typical σ-conjugated polymer, composed of alkyl side chains attached to the silicon (Si)-catenated main chain. First, PSi with linear alkyl side chains showed ...
Lin Jeng-Yu - - 2013
A transparent MoS(2)-graphene nanosheet (GNS) nanocomposite counter electrode (CE) was incorporated into a Pt-free dye-sensitized solar cell (DSC). The DSC assembled with the transparent MoS(2)-GNS CE therefore exhibited an impressive photovoltaic conversion efficiency of 5.81%, up to 93% of that obtained using the conventional Pt CE (6.24%).
Polisca A - - 2013
In six German Shepherds dogs, GnRH agonist implants (Deslorelin) were inserted subcutaneously one month after histological confirmation of benign prostatic hyperplasia (BPH). Prostatic volume (PV), characteristics of ejaculate, serum testosterone concentrations and Doppler parameters of prostatic and subcapsular arteries were detected at different time intervals, for 6 month. The prostatic volume ...
Tombal B - - 2013
We surveyed patients in France, Germany, Italy, Spain and Poland to examine information requirements and expectations of patients with prostate cancer. Patients were identified via their healthcare teams or via existing databases and interviewed by telephone, or in face-to-face interviews (Italy). Survey questions were either multiple choice or rank-based, and ...
Schueler Sabine - - 2013
OBJECTIVES: To evaluate the methodological quality of diagnostic accuracy studies on coronary computed tomography (CT) angiography using the QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) tool. METHODS: Each QUADAS item was individually defined to adapt it to the special requirements of studies on coronary CT angiography. ...
Yang Mingan - - 2013
In a linear mixed effects model, it is common practice to assume that the random effects follow a parametric distribution such as a normal distribution with mean zero. However, in the case of variable selection, substantial violation of the normality assumption can potentially impact the subset selection and result in ...
Yang Shung-Haur - - 2013
Background/Aims: We hypothesized an advantage of using carbohydrate antigen 19-9 (CA19-9) over carcinoembryonic antigen (CEA) in postoperative surveillance of colorectal cancer (CRC) patients with elevated preoperative serum CA19-9 (PreCA19-9). Methodology: We analyzed 197 CRC patients with elevated PreCA19-9 (>=37U/mL). Serum levels of CEA and CA19-9 were monitored postoperatively, according to ...
Ying Xiaofang - - 2013
Identification of high-risk prognostic markers for stage II colorectal cancer (CRC) is currently a big challenge. CD133 is one of the most commonly used CRC stem cell markers. However, its specificity is controversial. Recent studies have demonstrated that the AC133 epitope of CD133, not the CD133 protein, is responsible for ...
Ahn Jinho - - 2013
Amide-linked tripyridine derivatives , with a para-substituent, and , with a meta-substituent, were gelated in water or water-DMSO. The gelation capabilities of and were attributed to the cooperative effects of mainly CH-π and π-π stacking or strong intermolecular hydrogen bonding interactions between the amide groups. The fluorescence properties of gels ...
Yuan Yiyang - - 2013
Transgenic rice expressing Bacillus thuringiensis (Bt) endotoxins (Bt rice) for pest control is considered an important solution to food security in China. However, tests for potential effects on non-target soil organisms are required for environmental risk assessment. The soil collembolan Folsomia candida L. (Collembola: Isotomidae) is a potential non-target arthropod ...
Kwint Henk-Frans - - 2013
BACKGROUND: Many studies have investigated the effect of medication review on a variety of outcomes, but the elements of the interventions have been quite diverse. Moreover, implementation rates of recommendations also vary widely between studies. OBJECTIVE: The objective of this study was to investigate how the extent of collaboration between ...
Adappa Nithin D - - 2013
BACKGROUND: We recently demonstrated the bitter taste receptor T2R38 upregulates sinonasal mucosal innate defense in response to gram-negative quorum-sensing molecules through increased nitric oxide production and mucociliary clearance. T2R38 was initially identified in the quest to understand the variability in bitter taste perception to the compound phenylthiocarbamide (PTC) and demonstrated ...
Gisondi P - - 2013
BACKGROUND: Chronic plaque psoriasis is frequently associated to metabolic disorders including obesity. Anti-TNF-alpha treatments can induce body weight increase in patients with psoriasis. Information on the effect of ustekinumab on the body weight is not available. OBJECTIVE: To investigate whether therapy with ustekinumab is associated with changes in body mass ...
Mitchell Anna L - - 2013
OBJECTIVE: This case series documents the response of nine individuals with glucocorticoid-refractory Graves' orbitopathy (GO) to B cell depletion therapy with rituximab (RTX). CONTEXT: Graves' disease (GD) is one of the commonest autoimmune conditions and is frequently associated with inflammatory changes around the eyes (GO). GO frequently results in significant ...
Willets Katherine A - - 2013
Super-resolution far-field imaging has recently emerged as a novel strategy for imaging interactions between plasmonic nanostructures and single molecules with spatial resolution <5 nm. In these experiments, the emission centroid of a diffraction-limited spot is modeled as a two-dimensional Gaussian, allowing the position of an emitter to be determined with ...
Qiang Sheng Yang - - 2013
Background/Aims: Diabetes mellitus (DM) has been considered to be relevant to an increased risk of several different types of cancers. However, its relationship with extrahepatic cholangiocarcinoma (ECC) remains unclear. Methodology: To investigate a quantitative assessment of this relationship, we performed a meta-analysis to evaluate the association between diabetes and the ...
Lee Chil Won - - 2013
Benzo[4,5]thieno[2,3-b]pyridine (BTP) was newly developed as an electron deficient moiety for high triplet energy materials and two BTP derivatives with the BTP and carbazole groups were synthesized as high triplet energy bipolar host materials. The BTP derivatives were effective as the host materials for green and blue phosphorescent organic light-emitting ...
Castellanos-Cosano L - - 2013
Apical periodontitis (AP) is an inflammatory lesion around the apex of a tooth caused by bacterial infection of the pulp canal system. AP appears radiographically as a radiolucent periapical lesion (RPL). The elective treatment for teeth with AP is root canal treatment (RCT). No study is available about the frequency ...
Gao Yi - - 2013
The endosperm plays an important role in seed formation and germination, especially in rice (Oryza sativa). We used a high-throughput sequencing technique (RNA-Seq) to reveal the molecular mechanisms involved in rice endosperm development. Three cDNA libraries were taken from rice endosperm at 3, 6 and 10 days after pollination (DAP), which ...
Stoffel Karl K - - 2013
BACKGROUND: Previous studies comparing unipolar and bipolar hemiarthroplasty for treatment of displaced intracapsular femoral neck fractures in elderly patients have often lacked methodological power and yielded conflicting clinical results. The objective of this study was to compare the clinical outcomes from each implant in a randomized cohort of elderly patients ...
Navigante A - - 2013
OBJECTIVE: This study aims to determine the relationship between weakness and bioimpedance analysis (BIA)-derived phase angle in a population of untreated cancer patients with fatigue. METHODS: We prospectively evaluated 41 treatment-naive cancer patients of several origins that presented with performance status 1-2, weight loss >5 % in the last 6 months, and ...
Demir Ozlem - - 2013
Elk-1 is a member of the E-twenty-six (ETS) domain superfamily of transcription factors and has been traditionally associated with mitogen-induced immediate early gene transcription upon phosphorylation by mitogen activated protein kinases (ERK/MAPK). Elk-1 is not only upregulated but also phosphorylated in brain tumour cells. However, in this study, we show ...
Neller Daniel J - - 2013
Users of commonly employed actuarial risk assessment instruments (ARAIs) hope to generate numerical probability statements about risk; however, ARAI manuals often do not explicitly report data that are essential for understanding the classification accuracy of the instruments. In addition, ARAI manuals often contain data that have the potential for misinterpretation. ...
Czinn Steven J - - 2013
Gastroesophageal reflux (GER) is defined as the involuntary retrograde passage of gastric contents into the esophagus with or without regurgitation or vomiting. It is a frequently experienced physiologic condition occurring several times a day, mostly postprandial and causes no symptoms. These infants are also called 'happy spitters'. GER disease (GERD) ...
Li Lei - - 2013
PNAS-4, a novel pro-apoptotic gene, was activated during the early response to DNA damage. Previous studies have shown that hPNAS-4 can inhibit tumor growth when over-expressed in ovarian cancer cells. However, the underlying action mechanism remains elusive. In this work, we found that hPNAS-4 expression was significantly increased in SKOV3 ...
Huang Yifan - - 2013
ABSTRACT: BACKGROUND: Lipoprotein lipase (LPL) and serum 25-hydroxyvitamin D [25(OH)D] play important roles in the regulation of lipid metabolism. Although dyslipidemia is associated with insulin resistance (IR) and type 2 diabetes (T2D), there are limited data available regarding the relationship of LPL and 25(OH)D to IR and T2D at a ...
van der Straten Ariane - - 2013
We assessed the feasibility of a breath test to detect women's single or concurrent use of vaginal products by adding ester taggants to vaginal gel and condom lubricant. Healthy non-pregnant women were enrolled into a two-day cohort (N = 13) and a single-day cohort (N = 12) in San Francisco. Within each cohort, women ...
Thutupalli Shashi - - 2013
Droplet interface bilayers are a convenient tool to produce and explore lipid membrane properties. We discuss why their formation time in microfluidics can be three to six orders of magnitude faster compared to conventional bulk settings.
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