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Kubiak Clifford P - - 2013
This article describes research from our laboratory on the chemistry and spectroscopic properties of inorganic mixed-valence complexes. After a brief review of the seminal work of Taube, Creutz, Day, Robin, Hush, and others in the 1960s and the confounding efforts to identify the borderline between class II and III mixed-valence ...
O'Donnell Ryan M - - 2013
Remarkably little is known about metal-to-ligand charge transfer (MLCT) excited-state relaxation pathways for the ruthenium polypyridyl compounds commonly utilized in dye-sensitized solar cells. Herein, we report variable-temperature photoluminescence studies of compounds of the general type cis-Ru(LL)(2)(X)(2), where LL is a bipyridyl ligand and X is CN(-) or NCS(-), and contrast ...
Hernandez-Viezcas Jose A - - 2013
With the increased use of engineered nanomaterials such as ZnO and CeO2 nanoparticles (NPs), these materials will inevitably be released into the environment, with unknown consequences. In addition, the potential storage of these NPs or their biotransformed products in edible/ reproductive organs of crop plants can enter them into the ...
Golpe Rafael - - 2013
Background:Distance walked during the six-minute walk test (6MWT) predicts mortality in chronic obstructive pulmonary disease (COPD). The body weight of the patient affects the work required to walk. Calculated work during the 6MWT (6MWORK) may account for differences in walking distance resulting from change in body weight. Thus, 6MWORK might ...
Xu Yunze - - 2013
BACKGROUND: Malignant pheochromocytoma (PCC) is a rare catecholamine producing tumour with a poor prognosis. For many years predicting PCC behaviour has remained a highly difficult task. The aim of this study was to evaluate heat shock protein 90 (HSP90) and signal transducer and activator of transcription 3 (STAT3) as tissue-based ...
Kullberg Agneta - - 2013
The first-hand needs and demands of laypersons are not always considered when safety promotion programmes are being developed. We compared focal areas for interventions identified from residents' statements of safety needs with focal areas for interventions identified by local government professionals in a Swedish urban community certified by the international ...
Yan Xuzhou - - 2013
A chemically responsive diquaternary salt with π-extended surface was made. The host-guest complexation with chemo-responsiveness between three bis(m-phenylene)-32-crown-10 (BMP32C10) derivatives and this diquaternary salt guest was studied through the sequential addition of basic and acidic reagents (diethylamine and trifluoroacetic acid, respectively). Furthermore, the host-substituent effect on the complexation geometries of ...
Rivollier Julie - - 2013
Microwave irradiations allow the preparation of unsaturated bambusurils in 85% yield compared to 20% yield under classical reaction conditions. Five new bambusurils were synthesized including unsaturated derivatives Allyl(8)BU[4] and Allyl(12)BU[6] bearing diallylglycoluril units. The reactivity of Allyl(8)BU[4] was tested in a variety of organic reactions showing that this macrocycle acts ...
Hannan Edward L - - 2013
BACKGROUND: THERE ARE EVIDENCE-BASED GUIDELINES FOR STAGING OF PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION (STEMI) UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI), BUT WE ARE NOT AWARE OF ANY EVIDENCE COMPARING THE STRATEGY OF COMPLETE REVASCULARIZATION (CR) WITH PCI IN THE INDEX ADMISSION VERSUS THE STRATEGY OF STAGING IN A SUBSEQUENT ADMISSION FOR ...
Wang Li - - 2013
Objective To determine whether massage could help preterm infants improve weight gain, discharge from the hospital earlier, and promote the neurobehavioral development, a meta-analysis was conducted.Study Design MEDLINE, Embase, CINAHL, Dissertation Abstracts, and the Cochrane Library were searched up to January 2012. There were no language restrictions.Results In all, 611 articles were retrieved ...
Feigenbaum Annette - - 2013
In 1973, Singleton and Merten described two females with abnormal dentition, unique radiographic changes especially of the hands, and severe calcification and intimal weakening of the aortic arch and valve. Since then three additional cases with similar features have been reported and the diagnosis was suggested in another three individuals. ...
Watanabe Jonathan H - - 2013
Abstract Objective We sought to evaluate the relationship between different levels of medication possession ratio (MPR) attained and achievement of clinically meaningful reductions in lipid levels. Research design and methods Retrospective cohort study of 4 691 new statin users from the Department of Veteran Affairs (VA). Subjects were required to ...
Bixenstine Paul J - - 2013
Accurate patient identification is a National Patient Safety Goal. Misidentification of surgical specimens is associated with increased morbidity, mortality, and costs of care. The authors developed 12 practical, process-based, standardized measures of surgical specimen identification defects during the preanalytic phase of pathology testing (from the operating room to the surgical ...
Zhang Jiye - - 2013
Au-nanoparticle-decorated ZnS nanoarchitectures were fabricated by a simple hydrothermal approach combined with a deposition-precipitation method. After the deposition-precipitation process, 5-nm Au nanoparticles were homogeneously dispersed on the ZnS surface. In addition, the band gap of ZnS was also narrowed by the incorporation of a small amount of Au(I) ions. The ...
Wamberg L - - 2013
Inflammation is a key feature of obesity and type 2 diabetes. The active vitamin D metabolite, 1,25-dihydroxyvitamin D [1,25(OH)2D], modulates the inflammation in vitro. We studied whether inflammation in adipose tissue (AT) cultures could be reduced by incubation with 1,25(OH)2D in vitro, or by oral treatment with vitamin D in ...
Huang Kun - - 2013
BACKGROUND AND PURPOSE: Socioeconomic status is inversely associated with mortality after stroke; however, the reasons behind this finding are not well-understood. We undertook a study to determine whether posthospitalization care and medication adherence vary with neighborhood income. METHODS: We conducted a cohort study of 11 050 patients with ischemic stroke ...
Shi Niu - - 2013
OBJECTIVE: We recently demonstrated that combination treatment with NS3 protease and NS5B polymerase inhibitors succeeded in eradicating the virus in genotype 1b hepatitis C virus (HCV)-infected mice. In this study, we investigated the effect of combining an NS5A replication complex inhibitor (RCI) with either NS3 protease or NS5B inhibitors on ...
McGee Andrew John - - 2013
In this paper, we examine the lawfulness of a proposal to provide elective ventilation to incompetent patients who are potential organ donors. Under the current legal framework, this depends on whether the best interests test could be satisfied. It might be argued that, because the Mental Capacity Act 2005 (UK) ...
Dietl Nicolas - - 2013
The reactivities of the adamantane-like heteronuclear vanadium-phosphorus oxygen cluster ions [V(x) P(4-x) O(10) ](.) (+) (x=0, 2-4) towards hydrocarbons strongly depend on the V/P ratio of the clusters. Possible mechanisms for the gas-phase reactions of these heteronuclear cations with ethene and ethane have been elucidated by means of DFT-based calculations; ...
Hassan Rajib - - 2013
Objectives: The study has been designed to phenotype 200 Nepalese people residing in Bangladesh by measuring urinary ratio of 6β-hydroxycortisol/cortisol (metabolic ratio) and to genotype all the subjects for the presence of CYP3A4*1B, *2, *4, *5, *6, *10, *18, CYP3A5*3, and *6 alleles. Methods: Cortisol and 6β-hydroxycortisol were extracted and ...
Becks Lutz - - 2013
Stability and persistence of populations is of great interest for management and conservation purposes. Spatial dynamics can have a crucial role in population stability via synchronization, and beneficial and detrimental effects on population persistence have been shown. Despite a theoretical understanding of synchronization, empirical data on synchrony of populations are ...
Iyen-Omofoman Barbara - - 2013
INTRODUCTION: In the UK, most people with lung cancer are diagnosed at a late stage when curative treatment is not possible. To aid earlier detection, the socio-demographic and early clinical features predictive of lung cancer need to be identified. METHODS: We studied 12 074 cases of lung cancer and 120 ...
Zhao Weixiong - - 2013
Despite the significant progress in the measurements of aerosol extinction and absorption using spectroscopy approaches such as cavity ring down spectroscopy (CRDS) and photoacoustic spectroscopy (PAS), the widely used single wavelength instruments may suffer from the interferences of gases absorption present in the real environment. A second instrument for simultaneous ...
Konofaos Petros - - 2013
Promoting neurological recovery requires strategies that simultaneously provide protection to injured neurons and increase the numbers of neurons that extend axons while inducing more rapid and extensive axon regeneration across long nerve gaps. An agent that facilitates the speed and success of reinnervation will have direct applicability to the clinical ...
Leary Sam D - - 2013
BACKGROUND: A recent review found little evidence for substantial effects of modifiable maternal exposures on offspring blood pressure (BP), but this may have been because almost all the studies reported on BP in early and mid-childhood. METHODS: This study uses data on 4723 mother-child pairs, collected as part of the ...
Fleischmann Roy M - - 2013
OBJECTIVE: To assess radiographic progression, physical function, clinical disease activity, and safety in patients with rheumatoid arthritis (RA) who had inadequate response to methotrexate (MTX) and who were treated with tocilizumab-MTX or MTX during Year 2 of a 2-year study. METHODS: During Year 1, patients were randomized to placebo-MTX, 4 ...
Sørensen K D KD Department of Molecular Medicine, Aarhus University Hospital, Brendstrupgaardsvej 100, DK-8200 Aarhus N, Aarhus, Denmark. - - 2013
Novel biomarkers for prostate cancer (PC) are urgently needed. This study investigates the expression, epigenetic regulation, and prognostic potential of ANPEP in PC. Aminopeptidase N (APN; encoded by ANPEP) expression was analysed by immunohistochemistry using tissue microarrays representing 267 radical prostatectomy (RP) and 111 conservatively treated (CT) PC patients. Clinical ...
Wei Zuo-Fu - - 2013
In this study, the effect of UV irradiation (UV-A, UV-B and UV-C) on phytochemicals, total phenolics and antioxidant activity of postharvest pigeon pea leaves were evaluated. The response of pigeon pea leaves to UV irradiation was phytochemical-specific. UV-B and UV-C induced higher levels of phytochemicals, total phenolics and antioxidant activity ...
McLeod Monsey Chan - - 2013
BACKGROUND: Medication administration errors (MAEs) are a problem, yet methodological variation between studies presents a potential barrier to understanding how best to increase safety. Using the UK as a case-study, we systematically summarised methodological variations in MAE studies, and their effects on reported MAE rates. METHODS: Nine healthcare databases were ...
Martin Rhia M RM Department of Chemistry, Yale University, New Haven, Connecticut 06520, - - 2013
A stereo- and regioselective Diels-Alder reaction for the synthesis of highly substituted isoquinuclidines from dihydropyridines and electron-deficient alkenes has been developed. While reactions with activated dienophiles proceed readily under thermal conditions, the use of Lewis acid additives is necessary to facilitate cycloadditions for less reactive alkenes. This procedure affords the ...
Visootsak Jeannie J Department of Human Genetics, Emory University, Atlanta, Georgia 30033, USA. - - 2013
47,XXY/Klinefelter syndrome is the most common sex chromosomal aneuploidy, yet 64% of males with this condition go undiagnosed. 48,XXYY is less common and there is less known about the diagnosis. The objective of this study is to describe the diagnosis experiences of parents of males with 47,XXY and 48,XXYY. Parents ...
Platz Daniel - - 2013
Knowledge of surface forces is the key to understanding a large number of processes in fields ranging from physics to material science and biology. The most common method to study surfaces is dynamic atomic force microscopy (AFM). Dynamic AFM has been enormously successful in imaging surface topography, even to atomic ...
Neufeld Nathan J - - 2013
Lean Six Sigma (LSS) process analysis can be used to increase completeness of discharge summary reports used as a critical communication tool when a patient transitions between levels of care. The authors used the LSS methodology as an intervention to improve systems process. Over the course of the project, 8 ...
Fan Y-Y - - 2013
We have previously reported that intrarenal angiotensin II (Ang II) levels are increased long before diabetes becomes apparent in obese Otsuka-Long-Evans-Tokushima-Fatty (OLETF) rats, a model of type 2 diabetes. In this study, we examined the changes in intrarenal renin-angiotensin system (RAS) activity in the developing kidneys of OLETF rats. Ang ...
Bletsou Anna - - 2013
The occurrence and fate of 5 cyclic (D3 to D7) and 12 linear (L3 to L14) siloxanes were investigated in raw and treated wastewater (both particulate and dissolved phases) as well as in sludge from a wastewater treatment plant (WWTP) in Athens, Greece. Cyclic and linear siloxanes (except for L3) ...
Poulsen Mette H - - 2013
Argiotoxin-636 (ArgTX-636), a natural product from the spider Argiope lobata, is a potent but nonselective open-channel blocker of ionotropic glutamate (iGlu) receptors. Here, three series of analogues were designed to exploit selectivity among iGlu receptors, taking advantage of a recently developed solid-phase synthetic methodology for the synthesis of ArgTX-636 and ...
Vegliante Maria Carmela - - 2013
Mantle cell lymphoma (MCL) is one of the most aggressive lymphoid neoplasms whose pathogenesis is not fully understood. The neural transcription factor SOX11 is overexpressed in most MCL but is not detected in other mature B-cell lymphomas or normal lymphoid cells. The specific expression of SOX11 in MCL suggests that ...
Kohyama Noriko - - 2013
Hordatine A β-D-glucopyranoside was isolated from ungerminated barley grains for the first time and identified by MS spectrometry and one- and two-dimensional NMR spectroscopy. This compound was observed after 20 days after flowering (DAF) and was most abundant at 35 DAF when the dry weight of grains reached a maximum. ...
Santos Claire da Silva - - 2013
A protective or deleterious role of CD8(+)T cells in human cutaneous leishmaniasis (CL) has been debated. The present report explores the participation of CD8(+)T cells in disease pathogenesis as well as in the parasite killing. CD8(+) T cells accumulated in CL lesions as suggested by a higher frequency of CD8(+)CD45RO(+)T ...
Vogt Julie - - 2013
Aicardi-Goutières syndrome (AGS) is an encephalopathy of early childhood which is most commonly inherited as an autosomal recessive trait. The disorder demonstrates significant genetic heterogeneity with causative mutations in five genes identified to date. Although most patients with AGS experience a severe neonatal or infantile presentation, poor neurodevelopmental outcome and ...
Stavik Benedicte - - 2013
ABSTRACT: BACKGROUND: Tissue factor (TF) pathway inhibitor-1 (TFPI) is expressed in several malignant tissues- and cell lines and we recently reported that it possesses anti-tumor effects in breast cancer cells, indicating a biological role of TFPI in cancer. The two main splice variants of TFPI; TFPIalpha and TFPIbeta, are both ...
Kingdon Molly J - - 2013
HIV prevention messaging has been shown to reduce or delay high-risk sexual behaviors in young men who have sex with men (YMSM). Since the onset of the HIV/AIDS epidemic, a new generation of YMSM has come of age during an evolution in communication modalities. Because both these communication technologies and ...
Sommers Marilyn S - - 2013
Emergency departments (ED) are a point of care for many young adults and may provide a teachable moment leading to behavioral change. We determined the descriptive epidemiology of health-compromising behaviors in the young adult ED population by computing demographic-adjusted estimates of prevalence and frequency of hazardous drinking, risky driving, cigarette ...
Kumru Hatice - - 2013
OBJECTIVE: . Incomplete spinal cord injury (SCI) patients have the potential to regain some ambulatory function, and optimal reorganization of remaining circuits can contribute to this recovery. We hypothesized that repetitive transcranial magnetic stimulation (rTMS) may promote active recovery of motor function during gait rehabilitation. METHODS: . A total of ...
Hopkins J C - - 2013
AIM: Rectal bleeding may occur late after radiotherapy for prostate or bladder cancer, particularly when given by external beam (EBDXT) due to radiotherapy induced haemorrhagic telangectasia (RIHT). We present the results of trans-anal rectoscopic ball diathermy (TARD) for RIHT. METHOD: Data were collected on patients who received TARD for RIHT. ...
Santilli Giorgia G Molecular Immunology Unit, UCL Institute of Child Health, London, United - - 2013
Neuroblastoma is a rare childhood cancer whose high risk, metastatic form has a dismal outcome in spite of aggressive therapeutic interventions. The toxicity of drug treatments is a major problem in this pediatric setting. In this study, we investigated whether Polyphenon E, a clinical grade mixture of green tea catechins ...
Gantier Michael P - - 2013
The role of microRNAs (miRNAs) as fine-tuners of gene expression is now well established in most aspects of cellular biology. Critically, it is becoming apparent that characterization of miRNA regulation could further the understanding of elusive cellular processes. Here, I briefly review the current literature assessing the role of miRNAs ...
Wang Yanzhong Y Division of Health and Social Care Research, King's College London, 5th floor Capital House, 42 Weston St, London SE1 3QD, United Kingdom. - - 2013
To identify trends and differences between ethnic groups in survival after first-ever stroke and examine factors influencing survival. Population-based stroke register of first in a lifetime strokes between 1995 and 2010. Baseline data were collection of sociodemographic factors, stroke subtype, case mix, risk factors before stroke, and receipt of effective ...
Hoogendijk Arie J AJ Center for Infection and Immunity Amsterdam, 1105 AZ Amsterdam, The Netherlands. - - 2013
Adenosine monophosphate-activated protein (AMP)-activated kinase (AMPK) is a highly conserved kinase that plays a key role in energy homeostasis. Activation of AMPK was shown to reduce inflammation in response to lipolysaccharide in vitro and in vivo. 5-Aminoimidazole-4-carbox-amide-1-β-D-ribofuranoside (AICAR) is intracellularly converted to the AMP analog ZMP, which activates AMPK. Lipoteichoic ...
Wu W W Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, - - 2013
MicroRNA (miRNA, miR)-18a is a member of the miR-17-92 cluster, an important locus that is markedly overexpressed in several cancers and associated with cancer development and progression. However, the mechanism of action of the miR-17-92 cluster and its individual miRNAs are largely unknown. In this study, we investigated the expression ...
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