Search Results
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Sinclair Kenneth - - 2013
Mesenchymal stem cells (MSC) are a population of tissue resident adult progenitor cells which were originally identified in bone marrow, but have now been identified in many organs including the lung. Although their precise role in organ function remains incompletely defined, mounting evidence suggests that they are an important component ...
Pavlovic Aleksandra M - - 2013
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common heritable cause of stroke and vascular dementia in adults. We present a family from Serbia presenting with stroke and depression in the lack of vascular risk factors, with brain MRI indicating CADASIL. A novel NOTCH3 Gly89Cys ...
Hagely Katherine B - - 2013
Soybeans are an important source of protein-rich meal for livestock feed formulations. Recent changes in the cost of commodity-based sources of metabolizable energy (ME) inputs has put pressure on soybean meal to deliver both protein and ME in feed formulations. The non-oil fraction of soybean contains approximately 12% soluble carbohydrates, ...
Cormie P - - 2013
Background:Previous research has shown exercise to be an effective method to mitigate many adverse treatment-related effects of androgen suppression therapy (AST) but the potential impact of exercise on sexual activity remains unknown. The purpose of this investigation was to report the effect of a 12-week exercise program on sexual activity ...
Greysen S Ryan - - 2013
Despite recent guidelines promoting online professionalism, consequences for specific violations by physicians have not been explored. In this article, the authors gauged consensus among state medical boards in the United States (response rate, 71%) about the likelihood of investigations for violations of online professionalism by using 10 hypothetical vignettes. High ...
Helou Josiane - - 2013
Fox-Fordyce disease is an uncommon inflammatory disease of the apocrine sweat glands. Two recent reports indicated laser hair removal as a novel cause of axillary Fox-Fordyce disease. We report the first case of Fox-Fordyce disease developing in women after completing treatment with a depilatory hair laser appearing in the axillae, ...
Huen Ngar-Yee - - 2013
A higher frequency of regulatory T cells (Tregs) has been observed in peripheral blood mononuclear cells (PBMC) of patients with different types of solid tumors and hematological malignancies as compared to healthy donors. In prostate cancer patients, Tregs in PBMC have been shown to have increased suppressive function. Tumor-induced biological ...
Ghosh Debashree - - 2013
A detailed description of the implementation of the effective fragment potential (EFP) method in the Q-CHEM electronic structure package is presented. The Q-CHEM implementation interfaces EFP with standard quantum mechanical (QM) methods such as Hartree-Fock, density functional theory, perturbation theory, and coupled-cluster methods, as well as with methods for electronically ...
Xin Gang - - 2013
AIMS: B cell activating factor belonging to tumor necrosis factor family (BAFF) and a proliferation inducing ligand (APRIL) are two TNF-like cytokines those were found to be elevated in many autoimmune diseases. Anti-glomerular basement membrane (GBM) disease is a typical severe autoimmune disease characterized by raised serum anti-GBM antibodies. In ...
Zhu Shu-Ren - - 2013
We sequenced and characterized the complete mitochondrial genome of Channa argus, Channa maculata and their hybrid [C. maculata (♀) and C. argus (♂)]. All the three mitochondrial genomes contained the typical complement of 13 protein-coding genes, 22 transfer RNAs (tRNAs), 2 ribosomal RNAs (rRNAs) and 1 control region. The entire ...
Rahm Christoffer - - 2013
Rahm, C., Liberg, B., Wiberg-Kristoffersen, M., Aspelin, P. & Msghina, M. (2013). Rostro-caudal and dorso-ventral gradients in medial and lateral prefrontal cortex during cognitive control of affective and cognitive interference. Scandinavian Journal of Psychology. Characterizing the anatomical substrates of major brain functions such as cognition and emotion is of utmost ...
Méreau H - - 2013
The lens epithelium-derived growth factor (LEDGF/p75) tethers the mixed lineage leukemia (MLL1) protein complex to chromatin. Likewise, LEDGF/p75 tethers the human immunodeficiency virus 1 (HIV-1) pre-integration complex to chromatin. We previously demonstrated that expression of the C-terminal fragment fused to eGFP (eGFP-LEDGF(325-530)) impaired HIV-1 replication. Here, we explored this strategy ...
Morita Clara - - 2013
A series of long-chain amidoamine derivatives with different alkyl chain lengths (CnAA where n is 12, 14, 16 or 18) were synthesized and studied with regard to their ability to form organogels and to act as soft templates for the production of Au nanomaterials. These compounds were found to self-assemble ...
Lim Lionel S - - 2013
QUESTION What are the benefits and harms of general health checks in adults in primary care or community settings? REVIEW SCOPE Included studies compared general health checks (screening for &gt; 1 disease or risk factor in &gt; 1 organ system) with no health checks in adults in primary care or community settings. ...
Shin Seung-Hwan - - 2013
Antithymocyte globulin (ATG) is the drug of choice for immunosuppressive therapy (IST) in patients with severe aplastic anemia (SAA) ineligible for allogeneic stem cell transplantation. Recently, rabbit ATG with cyclosporine A has been used as a first-line IST regimen in patients with SAA because of unavailability of horse ATG. We ...
Ng Dominic S - - 2013
The HDL hypothesis has suffered damage in the past few years. Clinical trials have shown that raising HDL cholesterol levels does not improve cardiovascular disease (CVD) outcomes. In addition, Mendelian randomization studies have shown that DNA variants that alter HDL cholesterol levels in populations are unrelated to incident CVD events. ...
Sano Takako - - 2013
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib and erlotinib, is a critical problem in the management of patients with EGFR mutant lung cancer. Several mechanisms have been reported involved in this acquired resistance, including hepatocyte growth factor (HGF) activation of an alternative pathway. ...
Wang X - - 2013
BACKGROUND: Several node staging schemes have been proposed for gastric cancer. The optimal system remains controversial. METHODS: Patients with gastric cancer were identified from the Surveillance, Epidemiology, and End Results (SEER) database, and a Chinese patient cohort was used for independent validation. The prognostic performance of three node staging schemes ...
Zhang Huisheng - - 2013
Protein S100B is a clinically useful non-invasive biomarker for brain cell damage. A rapid chemiluminescence immunoassay (CLIA) for S100B in human serum has been developed. Fluorescein isothiocyanate (FITC) and N-(aminobutyl)-N-(ethylisoluminol) (ABEI) are used to label two different monoclonal antibodies of anti-S100B. Protein S100B in serum combines with labeled antibodies and ...
Moreno-Navarrete J M - - 2013
Objective:Recent studies linked circulating pigment epithelium-derived factor (PEDF) to obesity-associated insulin resistance, but the main source of circulating PEDF is unknown. We aimed to investigate liver and adipose tissue PEDF gene expression in association with obesity and insulin resistance.Design, subjects and methods:Three (two cross-sectional and one longitudinal) independent cohorts have ...
Thomas de Montpréville Vincent - - 2013
Thymic carcinomas represent the rarest and the more aggressive form of thymic epithelial tumors. We retrospectively reviewed a series of 37 consecutive cases seen in our hospital over a 15-year period. The patient group consisted of 14 female and 23 male patients, aged 31 to 80 years (mean = 57). Nineteen patients were ...
Capoccia Victor - - 2013
OBJECTIVE: Since 2008 Massachusetts has had universal health insurance with an individual mandate. As a result, only about 3% of the population is uninsured. However, patients who use behavioral health services are uninsured at much higher rates. This 2011 study sought to understand reasons for the discrepancy and identify approaches ...
Batuecas-Caletrio Angel - - 2013
Abstract Conclusions: The degree of caloric weakness before surgery influences faster or slower recovery of patients undergoing vestibular schwannoma surgery. The Dizziness Handicap Inventory (DHI) is a good index to show the recovery of patients as it relates directly to an improvement or not of the subjective visual vertical (SVV). ...
Glass A S - - 2013
Background:Active surveillance (AS) is an appropriate management strategy for men with low-risk prostate cancer. Most protocols recommend repeated prostate biopsy every 12-24 months. The purpose of this paper is to describe histological inflammation patterns in men on AS who underwent serial prostate biopsy for disease monitoring.Methods:We reviewed records of men ...
Hoar Sarah - - 2013
In the present study, we used Navon-type Cognitive Psychology 9: 353-383 (1977) hierarchical patterns to demonstrate that cognitive load eliminates a global perceptual bias and enhances the representation of local elements at unlimited exposure durations. We added a cognitive-load manipulation to Kimchi and Palmer's Journal of Experimental Psychology: Human Perception ...
Ter Veld Frank - - 2013
Wickerhamomyces ciferrii secretes tetraacetyl phytosphingosine (TAPS), and in this study, the catalyzing acetyltransferases were identified using mass spectrometry-based proteomics. The proteome of wild-type strain NRRL Y-1031 served as control and was compared to the tetraacetyl phytosphingosine defective mating type NRRL Y-1031-27. Acetylation of phytosphingosine in W. ciferrii is catalyzed by ...
Chiu Li-Fang - - 2013
Infrared microspectroscopy is an emerging approach for disease analysis owing to its capability for in situ chemical characterization of pathological processes. Synchrotron-based infrared microspectroscopy (SR-IMS) provides ultra-high spatial resolution for profiling biochemical events associated with disease progression. Spectral alterations were observed in cultured oral cells derived from healthy, precancerous, primary, ...
Byun W - - 2013
Objective:To determine the association between accelerometry-derived sedentary behavior and body mass index (BMI) z-score in preschool children, and to determine whether the association changed when applying three different accelerometry cutpoints for sedentary behavior.Design and subjects:Cross-sectional design. Data came from two completed studies: Children's Activity and Movement in Preschool Study (CHAMPS) ...
Wang Lijuan - - 2013
The electronic structure and charge transport property of 9,10-distyrylanthracene (DSA) and its derivatives with high solid-state luminescent efficiency were investigated by using density functional theory (DFT). The impact of substituents on the optimized structure, reorganization energy, ionization potential (IP) and electronic affinity (EA), frontier orbitals, crystal packing, transfer integrals and ...
Chen Yiyun - - 2013
Abstract Searching for modifiable perceptions that are associated with sexual risk behaviors among female sex workers (FSWs) are considered a priority in HIV/sexually transmitted disease preventions. Perception of peers' involvement in risk behaviors, a key correlate of individual risk behaviors, has barely been studied among FSWs. A self-administered questionnaire was ...
Saito Shuntaro - - 2013
PURPOSE: To develop a general strategy for optimizing monoclonal antibody (MAb) formulations. METHODS: Colloidal stabilities of four representative MAbs solutions were assessed based on the second virial coefficient (B (2)) at 20°C and 40°C, and net charges at different NaCl concentrations, and/or in the presence of sugars. Conformational stabilities were ...
French Jena - - 2013
Background: With our growing understanding of the immune system and mechanisms employed by the tumor to evade destruction, the field of cancer immunotherapy has been revitalized. Concurrent inflammation has long been associated with follicular cell-derived thyroid cancer (FDTC). In the last decade, much research has focused on characterizing the tumor-associated ...
Rutherford Bret R - - 2013
Placebo response in clinical trials of antidepressant medications is substantial and has been increasing. High placebo response rates hamper efforts to detect signals of efficacy for new antidepressant medications, contributing to trial failures and delaying the delivery of new treatments to market. Media reports seize upon increasing placebo response and ...
Lee Jin-Hyung - - 2013
Human pathogens can readily develop drug resistance due to the long-term use of antibiotics that mostly inhibit bacterial growth. Unlike antibiotics, antivirulence compounds diminish bacterial virulence without affecting cell viability and thus, may not lead to drug resistance. Staphylococcus aureus is a major agent of nosocomial infections and produces diverse ...
Miodek A - - 2013
We developed a biosensor based on the surface plasmon resonance (SPR) method for the study of the binding kinetics and detection of human cellular prions (PrP(C)) using DNA aptamers as bioreceptors. The biosensor was formed by immobilization of various biotinylated DNA aptamers on a surface of conducting polypyrrole modified by ...
Kvaløy K - - 2013
Objective:The impact of previously identified genetic variants directly or indirectly associated with obesity, were investigated at birth, adolescence and adulthood to provide knowledge concerning timing and mechanisms of obesity susceptibility with focus on sex differences.Design:Twenty four previously identified obesity- and eating disorder susceptibility loci were tested for association with adiposity ...
Oliveira-Santos Thiago - - 2013
The human face is a vital component of our identity and many people undergo medical aesthetics procedures in order to achieve an ideal or desired look. However, communication between physician and patient is fundamental to understand the patient's wishes and to achieve the desired results. To date, most plastic surgeons ...
Xin Che - - 2013
Abstract Background: In the system of the iontophoresis, the external electric field made the ions in the system moving directly, then, the current was generated. Because the current was contributed by all ions in the system, and the small ions with large amount often had higher conductibility than the drug ...
Mourad W F - - 2013
Background: Ceruminous mucoepidermoid carcinoma of the external auditory canal is extremely rare. This paper highlights the impact of concurrent chemoradiotherapy on the outcomes of this disease. Case report: A 47-year-old female presented with a 2-month history of otalgia and a mass in her right ear. Biopsy revealed high grade ceruminous ...
Chamilos Christos - - 2013
INTRODUCTION: Peri/intraventricular hemorrhage (PIVH) is more often seen in premature neonates and can lead to posthemorrhagic hydrocephalus, characterized by high mortality rate and neurodevelopmental delay. CASE REPORT: We report a case of in utero PIVH in a full-term neonate, which led to hydrocephalus. The infant developed at 8 months of gestational ...
Yun Jung-A - - 2013
BACKGROUND: Laparoscopic colectomy for malignancy currently is the standard operative technique together with open colectomy. Single-incision laparoscopic surgery (SIL) is a recent advance in minimally invasive surgical techniques. This study aimed to compare SIL right colectomy with conventional laparoscopy (CL) used to treat patients with colon cancer. METHODS: This study ...
Kazancioglu Hakki Oguz - - 2013
Abstract Objective. This is a questionnaire study aimed to collect information from Turkish dentists and oral and maxillofacial surgeons concerning common occupation-related health problems, their knowledge about these problems and the precautions they commonly took. Study design. This study involved a postal questionnaire survey of oral and maxillofacial surgeons and ...
Kim Tae Hyung - - 2013
PURPOSE:Clinical patterns in pediatric patients with dry eye syndrome and allergic conjunctivitis were investigated. METHODS:Children aged 6 to 15 years with dry eye symptoms were included. Slit-lamp examinations including tear film break-up time, Schirmer's test, and fluorescent staining were performed, and subjective symptoms were investigated. Patients with allergic conjunctivitis were ...
Belknap Steven M - - 2013
QUESTION Does cardiovascular (CV) risk associated with use of nonsteroidal antiinflammatory drugs (NSAIDs) after a first myocardial infarction (MI) differ by time since MI? METHODS DESIGN Cohort study with individual-level linkage of data from national registries. SETTING Denmark. PATIENTS 99 187 patients ≥ 30 years of age (mean age 69 y, 64% ...
Du Jiangbo - - 2013
FAT4 plays a crucial role in carcinogenesis as a key component of the Hippo signaling pathway. We hypothesized that potential functional polymorphisms in the FAT4 gene may modify the risk of esophageal cancer. To test this hypothesis, we evaluated the association between four nonsynonymous polymorphisms (rs1039808, rs12508222, rs1567047 and rs1014867) ...
Rosen Marc I - - 2013
OBJECTIVE: The examination that determines if a veteran has service-connected posttraumatic stress disorder (PTSD) affects veterans' lives for years. This study examined factors potentially associated with veterans' perception of their examination's quality. METHODS: Veterans (N=384) being evaluated for an initial PTSD service-connection claim were randomly assigned to receive either a ...
Murakami Ryusuke - - 2013
A study was conducted to evaluate the sensitivity of computer-aided detection (CAD) with full-field digital mammography in detection of breast cancer, based on mammographic appearance and histopathology. Retrospectively, CAD sensitivity was assessed in total group of 152 cases for subgroups based on breast density, mammographic presentation, lesion size, and results ...
Santarelli Danielle M - - 2013
RATIONALE: Changes in the cortical expression of small non-coding microRNA (miRNA) have been observed in postmortem analysis of psychotic disorders. Antipsychotic drugs (APDs) are the most effective treatment option for these disorders and have been associated with changes in gene expression. MicroRNA regulate numerous genes involved in brain development and ...
Orr Elizabeth M J - - 2013
Background: Video feedback (VF) interventions effectively reduce social anxiety symptoms and negative self-perception, particularly when they are preceded by cognitive preparation (CP) and followed by cognitive review. Aims: In the current study, we re-examined data from a study on the efficacy of a novel VF intervention for individuals high in ...
Cregan Christina - - 2013
This multi-method study investigated a sample of adult streetworkers (n = 107) in Melbourne, Australia in 2008. We contacted outdoor prostitutes through four "drop-in" centers run by not-for-profit organizations. Drug use was the over-riding common characteristic of most of these streetworkers. Using emotional labor theory as a theoretical framework, we hypothesized that ...
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