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Singh Manju Rawat MR University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.), - - 2013
Wound is one of the oldest suffering associated with the mankind and its history is as old as humanity. Advances in the field of medical sciences created a pile of knowledge and paved the path for the development of a separate branch specifically devoted for wound healing. The understanding and ...
Vadlamudi Harini Chowdary - - 2013
Abstract Colonic diseases are more prevalent during the past decade. Colorectal cancer, ulcerative colitis, Crohn's disease, diverticulitis, irritable bowel syndrome are the major reported colonic diseases. Innovative strategies are defensible in order to advance the efficacy of colonic disease treatment. During the past decade there has been an extensive advance ...
Mu Wanmeng - - 2013
Epilactose (4-O-β-D-galactopyranosyl-D-mannose), an epimer of lactose, is a rare disaccharide existing extremely small quantities in heat-treated milk, in which epilactose is produced by non-enzymatic catalysis from lactose. This disaccharide is a kind of non-digestible carbohydrate, has a good prebiotic effect, and promotes intestinal mineral absorption. This article presents a review ...
Hama Taketsugu - - 2013
BACKGROUND: A possible mechanism of cyclosporine (CsA) nephrotoxicity is tubular apoptosis. Endoplasmic reticulum (ER) stress has been shown to be an apoptosis activator. Glucose-regulated proteins 78 and 94 (GRP78, GRP94, respectively) are ER stress-induced chaperones. Eukaryotic translation initiation factor 2α (EIF2α) attenuates protein synthesis. If stress is prolonged, cells undergo ...
Zhang Zhenjun - - 2013
The effect of a small gap sleeve suture at the distal anastomosis of a nerve graft on promoting nerve regeneration and functional recovery was investigated by experimental observation. The model of common peroneal nerve defect in Sprague-Dawley (SD) rats was established, and an autologous sural nerve graft repair was performed. ...
Sekse Ragnhild Johanne Tveit - - 2013
BACKGROUND: Women who have been through gynaecological cancer, experience challenges on many levels after diagnosis and treatment. Studies show that, in order to help women in their rehabilitation process, there is a need for holistic care and follow-up. AIM: The aim of this qualitative study is to provide insight into ...
Alreshidi M A - - 2013
One hundred and twenty methicillin-resistant Staphylococcus aureus (MRSA) isolated from cancer and non-cancer patients in Saudi Arabia were investigated for antibiotic resistance, virulence determinants and genotypes. The majority of MRSA isolates from cancer (n = 44, 73.3 %) and non-cancer patients (n = 34, 56.7 %) were multi-resistant to more than four classes of antibiotics. Virulence ...
Rai M F MF Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes-Jewish Hospital, St Louis, MO, - - 2013
Aging and obesity contribute to the initiation and progression of osteoarthritis with little information on their relation to gene expression in joint tissues, particularly the meniscus. Here, we test the hypothesis that patient age and body mass index (BMI) correlate with the expression of osteoarthritis- and obesity-related gene signatures in ...
Harper Mhairi M - - 2013
The ability to develop new and sensitive methods of biomolecule detection is crucial to the advancement of pre-clinical disease diagnosis and effective patient specific treatment. Surface enhanced Raman scattering (SERS) is an optical spectroscopy amenable to this goal, as it is capable of extremely sensitive biomolecule detection and multiplexed analysis. ...
Katz Philip O - - 2013
OBJECTIVES:Optimal bowel preparation is vital for the efficacy and safety of colonoscopy. The inconvenience, discomfort, required consumption of large volumes of product, and potential adverse effects associated with some bowel preparations deter patients from colonoscopy and may provide inadequate cleansing. A dual-action, non-phosphate, natural orange-flavored, low-volume preparation containing sodium picosulfate ...
Smith Kirk L - - 2013
The authors, representing two of the "signature" community service learning (CSL) programs in the 2010 Flexner Centenary volume of Academic Medicine, provide details of their programs - Frontera de Salud, a community-based program at the University of Texas Medical Branch, and the East Harlem Health Outreach Partnership, a clinic-based program ...
Abdelazim Ibrahim A - - 2013
AIMS: Lower vaginal swabs were collected to compare the intrapartum polymerase chain reaction (PCR) test to the standard antepartum culture for detection of group B streptococcus (GBS) colonisation. MATERIALS AND METHODS: Four hundred and forty-five pregnant women with documented antepartum GBS cultures, who did not receive either antepartum or intrapartum ...
Haga Hans-Jacob - - 2013
This study aims to measure the serum level of 25-hydroxyvitamin D(3) (25-OH-D(3)) in 302 patients with rheumatoid arthritis (RA), studying the association to disease activity. Three hundred two RA patients underwent clinical examination and serological analysis. 25-Hydroxyvitamin D(3) was determined by high-performance liquid chromatography-tandem mass spectrometry. Vitamin D(3) deficiency defined ...
Yang Fan - - 2013
rSj16, a recombined protein from Schistosoma japonicum, has been identified as an anti-inflammatory molecule. In this study, we demonstrated that rSj16 strongly suppressed the growth of murine myeloid leukemia WEHI-3B JCS cells in a dose- and time-dependent manner. rSj16 induced apoptosis by increasing the proportion of sub-G1 apoptotic cells as ...
Mai Zhimao - - 2013
The gene BglNH encoding a β-glucosidase was cloned from a marine streptomycete. Sequence analysis revealed that BglNH encoded a 456-aa peptide with a calculated mass of 51 kDa. The deduced amino acid sequence of BglNH showed the highest identities of 61 % with known β-glucosidases and contained a catalytic domain which belonged ...
Kim H R - - 2013
Study design:A 6-month follow-up study.Objectives:To investigate the outcome of transanal irrigation (TAI) in patients with spinal cord injury (SCI) and to identify factors significantly related to clinical success.Setting:Survey for community-dwelling patients with SCI in South Korea.Methods:Between December 2010 and March 2012, TAI was initiated with 52 patients (41 men; age: ...
Paun Gabriela - - 2013
Abstract This study was meant to determine the inhibitory activity of tannins and flavonoid compounds from Geranium robertianum, Helleborus purpurascens and Hyssopus officinale plant polyphenol rich extracts against urease and α-chymotrypsin. The G. robertianum, H. purpurascens and H. officinale extracts were purified and concentrated by microfiltration and ultrafiltration. Phenolic compounds ...
Sakai Shinji - - 2013
We report a method for preparing cell-laden hydrogel tubes. This method uses a coaxial double-orifice spinneret, simpler than triple-orifice spinnerets which have been used for preparing similar constructs. The intended application was to create a template for preparing filament-like structures composed of two heterogeneous living cell layers. An aqueous solution ...
Olausson E A - - 2013
Background  Scintigraphy, the gold standard to measure gastric emptying, is expensive and not widely available. Therefore, we compared emptying of radiopaque markers (ROM) from the stomach, by use of fluoroscopy, with scintigraphy in patients with insulin-treated diabetes. Methods  On the same day we measured gastric emptying of 20 ROM using ...
Miernyk Karen - - 2013
BACKGROUND: Helicobacter pylori (H. pylori) infection has been correlated with low serum ferritin and iron deficiency. As a secondary analysis of a study of H. pylori reinfection, we investigated the association of H. pylori infection and the effect of its eradication on serum ferritin and iron deficiency. METHODS: Alaska Native adults undergoing esophagogastroduodenoscopy ...
Moist Louise - - 2013
QUESTION In adults with type 2 diabetes mellitus, does intensive blood pressure (BP) control improve clinical outcomes more than standard BP control? REVIEW SCOPE Included studies compared antihypertensive therapies to achieve prespecified BP targets in adults who had type 2 diabetes, and assessed ≥ 1 of mortality, myocardial infarction (MI), or ...
Cassidy Aedín A Department of Nutrition, Norwich Medical School, University of East Anglia, Norwich, - - 2013
Our current knowledge of modifiable risk factors to prevent myocardial infarction (MI) in young and middle-aged women is limited, and the impact of diet is largely unknown. Dietary flavonoids exert potential beneficial effects on endothelial function in short-term trials; however, the relationship between habitual intake and risk of MI in ...
Keaveny Eric - - 2013
Recent advances in micro- and nano-scale fabrication techniques allow for the construction of rigid, helically-shaped micro-swimmers that can be actuated using applied magnetic fields. These swimmers represent the first steps toward the development of micro-robots for targeted drug delivery and minimally invasive surgical procedures. To assess the performance of these ...
Cornelius Jan Frederick - - 2013
BACKGROUND: About 90 % of meningiomas are benign (WHO grade I), atypical and anaplastic variants exist (WHO grade II/III, 10 %). Tumour grade has important implications for management. Non-invasive diagnosis of tumour grade is still not feasible. The purpose of this survey was to analyse epidemiological risk factors such as sex, age ...
Williams Monique - - 2013
Abstract Mycobacterium tuberculosis (Mtb) and other members of the Mtb complex possess an expanded complement of genes for the biosynthesis of molybdenum cofactor (MoCo), a tricyclic pterin molecule that is covalently attached to molybdate. This cofactor allows the redox properties of molybdenum to be harnessed by enzymes in order to ...
Giangaspero Massimo - - 2013
A serological survey was carried out in the northern prefectures of Hokkaido, Iwate and Aomori in Japan, for the presence of antibodies against Toxoplasma gondii, Chlamydia psittaci var. ovis, Mycobacterium paratuberculosis, Coxiella burnetii, Brucella spp., Leptospirosis, and orf virus (ORFV). Out of 267 samples tested, highest overall prevalence (28.78%) was ...
Ho Jennifer H - - 2013
High-fat diet (HFD)-induced glucose intolerance and insulin resistance increases the chances of developing type-2 diabetes and cardiovascular disease. To study the mechanism(s) by which a HFD impairs glucose tolerance, we used a quantitative proteomic platform that integrated pI-based OFFGEL fractionation and iTRAQ labeling to profile the temporal changes in adipose ...
Shin Seong Sik - - 2013
Ternary oxides are potential candidates as an electron-transporting material that can replace TiO(2) in dye-sensitized solar cells (DSSCs), as their electronic/optical properties can be easily controlled by manipulating the composition and/or by doping. Here, we report a new highly efficient DSSC using perovskite BaSnO(3) (BSO) nanoparticles. In addition, the effects ...
Hirsch Calvin - - 2013
QUESTION In elderly patients who report memory complaints to their primary care physicians, does ginkgo biloba extract reduce risk for Alzheimer disease (AD)? METHODS DESIGN Randomized placebo-controlled trial (GuidAge). ClinicalTrials.gov NCT00276510. ALLOCATION Concealed.* BLINDING Blinded* (patients, clinicians, and dementia adjudication committee). FOLLOW-UP PERIOD Median 5 years. Follow-up after 2 years ...
Heller Kristin N KN The Ohio State University, Columbus, OH, - - 2013
Duchenne muscular dystrophy (DMD) is a severe muscle disease caused by mutations in the DMD gene, with loss of its gene product, dystrophin. Dystrophin helps link integral membrane proteins to the actin cytoskeleton and stabilizes the sarcolemma during muscle activity. We investigated an alternative therapeutic approach to dystrophin replacement by ...
Blevins Erin - - 2013
Studies of aquatic locomotion typically assume that organisms move through unbounded fluid. However, benthic fishes swim close to the substrate and will experience significant ground effects, which will be greatest for fishes with wide spans such as benthic batoids and flatfishes. Ground effects on fixed-wing flight are well understood, but ...
Allena Rachele - - 2013
Cell migration triggered by pseudopodia (or "false feet") is the most used method of locomotion. A 3D finite element model of a cell migrating over a 2D substrate is proposed, with a particular focus on the mechanical aspects of the biological phenomenon. The decomposition of the deformation gradient is used to ...
Kim Eui Hyun - - 2013
BACKGROUND: Intraoperative magnetic resonance imaging (iMRI) is proven to be advantageous in transsphenoidal surgery (TSS) for pituitary adenomas. We evaluated the efficacy of low-field iMRI. Also, we described several techniques to enhance the visibility of the tumor resection margin. METHODS: Two hundred twenty-nine patients who underwent TSS using low-field iMRI ...
Oláh Anna V AV Department of Laboratory Medicine, Medical and Health Science Center, University of Debrecen, 98 Nagyerdei krt., Debrecen 4032, Hungary. - - 2013
Smith-Lemli-Opitz syndrome (SLOS), a multiple congenital anomaly with severe mental retardation, is caused by decreased activity of 7-dehydrocholesterol reductase. Fifteen Hungarian patients were diagnosed with SLOS on the basis of clinical symptoms, serum cholesterol, 7-dehydrocholesterol, and molecular genetic testing. Their age at the time of diagnosis in mild SLOS (n ...
Soda Kosuke - - 2013
Widespread outbreaks of highly pathogenic avian influenza (HPAI) caused by H5N1 viruses occurred in wild birds in Japan from 2010-11. Forty out of sixty-three deceased wild birds belonged to the order Anseriformes, and mandarin duck was one of the dominant species. To estimate the risk of mandarin ducks as a ...
Zhang Xiaoyue - - 2013
The mechanical characteristics of human red blood cell (RBC) membrane change due to C(60) nanoparticle (NP) infiltration have been investigated in the present work. Using experimental approaches, including optical tweezer (OT) stretching and atomic force microscopy (AFM) indentation, we found that RBCs in the presence of C(60) NPs are softer ...
Na Keun - - 2013
Although alpha-fetoprotein is currently the major serologic biomarker for hepatocellular carcinoma (HCC), it cannot efficiently distinguish this cancer from other forms of liver disease in early diagnosis due to its low sensitivity. The aim of this study is to compare human carboxylesterase 1 (hCE1) biomarker sensitivity and specificity versus alpha-fetoprotein ...
Cuddeback Gary S - - 2013
OBJECTIVE: A previous study of a recovery-oriented assertive community treatment initiative (PACT) in Washington State found reductions in state psychiatric hospital use and related costs for PACT participants, especially in the first six months after enrollment and for consumers who were high users of the state psychiatric hospital before ACT ...
Lloret-Linares C - - 2013
Context:The care of patients with hypothalamic obesity is challenging.Objective:To compare body composition, basal metabolic rate (BMR) and metabolic outcomes of adults, with lesional or genetic hypothalamic obesity, with obese patients suffering from primary obesity, once matched for body mass index (BMI).Design and patients:Adults with hypothalamic obesity of genetic origin (Prader ...
Mousavi Seyed Mohsen - - 2013
Background. There are large geographic differences in breast cancer risk but whether survival differs between low- and high-risk groups is less well-established. As the survival of cancer depends on the level of healthcare and awareness of disease risks, subtle differences in cancer biology cannot be revealed in international comparisons. Instead, ...
Tandon Rajendra R Sitaram Bhartia Institute of Science and Research, B-16, Mehrauli Institutional Area, New Delhi 110016, - - 2013
Rheumatic fever is one of the most-neglected ailments, and its pathogenesis remains poorly understood. The major thrust of research has been directed towards cross-reactivity between streptococcal M protein and myocardial α-helical coiled-coil proteins. M protein has also been the focus of vaccine development. The characteristic pathological findings suggest that the ...
Böttcher B B Department of Gynecological Endocrinology and Reproductive Medicine, Innsbruck Medical University, Innsbruck, - - 2013
To measure skin thickness in patients with polycystic ovary syndrome (PCOS) in comparison to controls and to examine a possible association with sex steroids, body mass index, lipid profile and hyperinsulinemia. Thirty patients with confirmed PCOS were compared to thirty-two women presenting for infertility workup. Skin thickness was measured using ...
Greysen S Ryan - - 2013
Despite recent guidelines promoting online professionalism, consequences for specific violations by physicians have not been explored. In this article, the authors gauged consensus among state medical boards in the United States (response rate, 71%) about the likelihood of investigations for violations of online professionalism by using 10 hypothetical vignettes. High ...
Benarroch Eduardo E - - 2013
The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels belong to the superfamily of pore-loop cation channels. In mammals, the HCN channel family comprises 4 members (HCN1-4) that are expressed in heart and nervous system. HCN channels are activated by membrane hyperpolarization, are permeable to Na+ and K+, and are constitutively open at ...
Helou Josiane - - 2013
Fox-Fordyce disease is an uncommon inflammatory disease of the apocrine sweat glands. Two recent reports indicated laser hair removal as a novel cause of axillary Fox-Fordyce disease. We report the first case of Fox-Fordyce disease developing in women after completing treatment with a depilatory hair laser appearing in the axillae, ...
Ghosh Debashree - - 2013
A detailed description of the implementation of the effective fragment potential (EFP) method in the Q-CHEM electronic structure package is presented. The Q-CHEM implementation interfaces EFP with standard quantum mechanical (QM) methods such as Hartree-Fock, density functional theory, perturbation theory, and coupled-cluster methods, as well as with methods for electronically ...
Xin Gang - - 2013
AIMS: B cell activating factor belonging to tumor necrosis factor family (BAFF) and a proliferation inducing ligand (APRIL) are two TNF-like cytokines those were found to be elevated in many autoimmune diseases. Anti-glomerular basement membrane (GBM) disease is a typical severe autoimmune disease characterized by raised serum anti-GBM antibodies. In ...
Merulla Davide - - 2013
Escherichia coli-based bioreporters for arsenic detection are typically based on the natural feedback loop that controls ars operon transcription. Feedback loops are known to show a wide range linear response to the detriment of the overall amplification of the incoming signal. While being a favourable feature in controlling arsenic detoxification ...
Rao Nithya - - 2013
The metalloproteinase ADAMTS4/aggrecanase-1 is highly expressed in cartilage and has been implicated in human arthritis. Although abundantly expressed in many types of cancer, its role in cancer remains unknown. In this work, we demonstrate for the first time that full-length ADAMTS4 or its catalytically more active N-terminal 53 kDa autocatalytic ...
Gianicolo Emilio Antonio Luca - - 2013
Exposure to air pollutants has been associated with increased hospital admissions (HAs) for respiratory and cardiovascular diseases. This work describes a short-term epidemiological study in Brindisi, a highly industrialized town in Southern Italy. The effects of daily exposure to PM(10) and NO(2) on daily HAs for cardiac, respiratory, and cerebrovascular ...
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