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Results 601 - 650 of 2923
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Shobha Nandavar - - 2013
BACKGROUND: We sought to assess the hypothesis that length and volumes of middle cerebral artery (MCA) thrombus were associated with disappearance of the hyperdense middle cerebral artery sign (HMCAS) in acute ischemic stroke. METHODS: This is a retrospective cohort study of acute ischemic stroke patients with MCA occlusion admitted to ...
Adams Denise - - 2013
OBJECTIVE:Complementary and alternative medicine (CAM) use is high among children and youth with chronic illnesses. The objective of this study was to assess the prevalence and patterns of CAM use in 10 subspecialty clinics in Canada and to compare CAM use between 2 geographically diverse locations.METHODS:This survey was carried out ...
Escudero Alberto - - 2013
Europium-doped calcium hydroxyapatite and fluoroapatite nanophosphors functionalized with poly acryl acid (PAA) have been synthesized through an one-pot microwave-assisted hydrothermal method from aqueous basic solutions containing calcium nitrate, sodium phosphate monobasic, PAA, as well as sodium fluoride in the case of the fluoroapatite particles. In both cases a spindle-like morphology ...
Sia D - - 2013
Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with very poor prognosis. Genome-wide, high-throughput technologies have made major advances in understanding the molecular basis of this disease, although important mechanisms are still unclear. Recent data have revealed specific genetic mutations (for example, KRAS, IDH1 and IDH2), epigenetic silencing, aberrant signaling pathway ...
Kawasuji Takashi - - 2013
This work is a continuation of our initial discovery of a potent monocyclic carbamoyl pyridone HIV-1 integrase inhibitor that displayed favorable antiviral and pharmacokinetic properties. We report herein a series of bicyclic carbamoyl pyridone analogs to address conformational issues from our initial SAR studies. This modification of the core unit ...
Cree Bruce Ac - - 2013
For physicians who care for patients with multiple sclerosis (MS), the use of disease-modifying therapies (DMTs) during the conception period and pregnancy raises important safety considerations. All DMTs have potential adverse effects on fertility, pregnancy outcomes, and breastfed infants. Although physicians are reluctant to prescribe DMTs to MS patients who ...
Bochatay Valentin N - - 2013
A convenient one-pot palladium-catalyzed cascade process for the preparation of both benzoxazoles and benzothiazoles has been developed. While these reactions proceed to give similar compounds the mechanisms governing the processes are different as are the experimental conditions employed.
KÅ‚adna Aleksandra - - 2013
The direct effect of the four catecholamines (adrenaline, noradrenaline, dopamine and isoproterenol) on superoxide anion radicals (O2-•) was investigated. The reaction between 18-crown-6-ether and potassium superoxide in dimethylsulfoxide was used as a source of O2-•. The reactivity of catecholamines with O2-• was examined using chemiluminescence, reduction of nitroblue tetrazolium and ...
Lagarde Pauline - - 2013
PURPOSESynovial sarcoma (SS) occurs in both children and adults, although metastatic events are much more common in adults. Whereas the importance of the t(X;18) translocation in SS oncogenesis is well established, the genetic basis of SS metastasis is still poorly understood. We recently reported expression (CINSARC; Complexity Index in Sarcoma) ...
Garcea Giuseppe - - 2013
BACKGROUND: Liver cysts are common, occurring in up to 5% of the population. For many types of cysts, a variety of different treatment options exist and the preferred management is unclear. METHODS: A PubMed and Medline literature review was undertaken and articles pertaining to the diagnosis and management of cystic ...
Schaumann Reiner - - 2013
The present study was designed to investigate the killing activity of levofloxacin, gatifloxacin, moxifloxacin, and garenoxacin against 12 Bacteroides fragilis strains by kill kinetics over time. MIC values were determined by Etest and agar dilution, respectively. B. fragilis strains were divided according to their MIC values into two groups: one ...
Ishikawa Toru - - 2013
This study empirically examined the retention of large-scale spatial memory, taking different types of spatial knowledge and levels of sense of direction into consideration. A total of 38 participants learned a route from a video and conducted spatial tasks immediately after learning the route and after 2 weeks or 3 ...
Pickering Karen - - 2013
Effective wound closure mechanisms are essential for maintenance of epithelial structure and function. The repair of wounded epithelia is primarily driven by the cells bordering the wound, which become motile after wounding, forming dynamic actin protrusions along the wound edge. The molecular mechanisms that trigger wound edge cells to become ...
Nascimento Cássio do - - 2013
OBJECTIVE: Microorganisms harboring the oral cavity, mainly those related to periodontal diseases, are the most potential etiologic factor of failure in long-term implant treatment. The material used for abutment components may influence the adhesion and colonization of microbial species. The aim of this in vivo investigation was to evaluate the ...
Mekala Naveen Kumar - - 2013
The osteogenic potential of mesenchymal stem cells (MSCs) from umbilical cord blood (UCB) on porous poly lactide-co-glycolide (PLGA) scaffolds have been reported to differentially support osteogenic differentiation based on polymer composition (80:20, 75:25 and 70:30 percent of PLA: PGA, respectively). Along with polymer composition; fused NaCl crystal matrix prior to ...
Zhao Chao - - 2013
The emergence and re-emergence of microbial infection demand an urgent need to develop effective biomaterials that prevent biofilm formation and associated bacterial infection. In this work, we have synthesized and characterized hybrid poly(n-hydroxyethylacrylamide) (polyHEAA)/salicylate (SA) hydrogels with integrated antifouling and antimicrobial capacities. The antifouling efficacy of polyHEAA hydrogels was examined ...
Nogueira Raul G - - 2013
BACKGROUND: Conventional non-invasive angiographic techniques for evaluating cerebral Arteriovenous Malformations (cAVMs) after embolization treatment are limited by their inability to acquire time-resolved images. We describe the use of dynamic contrast-enhanced magnetic resonance angiography (MRA) in the evaluation of residual arteriovenous shunting in cAVMs following Onyx embolization. METHODS: Six subjects who ...
Li H - - 2013
BACKGROUND AND OBJECTIVE: Diabetes mellitus is believed to increase the risk and severity of periodontitis. However, less evidence is available on the converse effects of periodontitis on diabetes. The objective of the study was to investigate to what degree experimental periodontitis induced by Porphyromonas gingivalis might influence the onset and ...
Hu Xiaoqing - - 2013
In an event-related potential (ERP)-based concealed information test (CIT), we investigated the effect of manipulated awareness of concealed information on the ERPs. Participants either committed a mock crime or not (guilty vs. innocent) before the CIT, and received feedback regarding either specific (high awareness) or general (low awareness) task performance ...
Grimaldi-Bensouda Lamiae - - 2013
PURPOSE: Patients' self-reported vaccine exposure (PS) may be subject to memory errors and other biases. Physicians' prescription records and other medical records (MR) do not capture noncompliance with vaccination. This study compared PS with MR for influenza, 23-valent pneumococcal, and human papillomavirus (HPV) vaccines. METHODS: The Pharmacoepidemiologic General Research Extension ...
Rusman Yudi - - 2013
During a survey of actinobacteria known to suppress the growth of Streptomyces scabies (the causative agent of potato scab disease) in vivo, six new rhamnosylated alkaloids, the solphenazines A-F (1-6), were isolated from a biological control strain of Streptomyces (DL-93). The known rhamnosyl analogue of paraben (9) was also isolated ...
Liamsuwan Thiansin - - 2013
The paper presents calculated cross sections for bare and dressed carbon projectiles of charge states q (0 to 6) with energies 1-10(4) keV u(-1) impacting on molecular water and atomic neon targets. The cross sections of water are of interest for radiobiological studies, but there are very few experimental data for water ...
Marchini Aïda Kawkabani - - 2013
BACKGROUND AND PURPOSE: Unruptured anterior inferior cerebellar artery (AICA) aneurysms are rare but potentially lethal cerebellopontine angle (CPA) lesions that may be misdiagnosed as vestibular schwannomas when they present with vestibulo-cochlear symptoms. METHODS: We report two cases of unruptured but symptomatic AICA aneurysms initially referred to us as atypical vestibular ...
Tsai H-Y - - 2013
Lung cancer is the leading cause of cancer deaths and is the most occurring malignancy worldwide. Unraveling the molecular mechanisms involved in lung tumorigenesis will greatly improve therapy. During early tumorigenesis, rapid proliferating tumor cells require increased activity of endoplasmic reticulum (ER) for protein synthesis, folding and secretion, thereby are ...
Chaudhri Anuj - - 2013
Coarse-grained computational models of therapeutic monoclonal antibodies and their mutants can be used to understand the effect of domain-level charge-charge electrostatics on the self-association phenomena at high protein concentrations. The coarse-grained models are constructed for two antibodies at different coarse-grained resolutions using six different concentrations. It is observed that a ...
Milne I A - - 2013
This paper analyses a set of velocity time histories which were obtained at a fixed point in the bottom boundary layer of a tidal stream, 5 m from the seabed, and where the mean flow reached 2.5 m s(-1). Considering two complete tidal cycles near spring tide, the streamwise turbulence intensity during non-slack ...
Woodward Amanda T - - 2013
BACKGROUND: Previous epidemiological and clinical research on mental disorders has treated Blacks as a homogenous group and yet Blacks of Caribbean descent and African Americans differ with respect to ethnicity, national heritage, living circumstances, and immigration status. The purpose of this article is to examine the prevalence of major depressive ...
Tanaka K - - 2013
BACKGROUND AND OBJECTIVE: Studies reporting on the association between smoking and periodontal disease have mostly focused on active smoking. The purpose of this study was to examine the relationships between active smoking and exposure to second-hand smoke at home and at work and the prevalence of periodontal disease among young ...
Bachman Jerald G - - 2013
High school students who spend long hours in paid employment during the school year are at increased risk of lower grades and higher substance use, although questions remain about whether these linkages reflect causation or prior differences (selection effects). Questions also remain about whether such associations vary by socioeconomic status ...
Promislow Steven - - 2013
ABSTRACT: BACKGROUND: Previous studies have demonstrated Aboriginals are less likely to receive a renal transplant in comparison to Caucasians however whether this applies to the entire population or specific subsets remains unclear. We examined the effect of age on renal transplantation in Aboriginals. METHODS: Data on 30,688 dialysis (Aboriginal 2,361, ...
Noguchi Fumiya - - 2013
It has recently been unveiled that a wide variety of microbial eukaryotes (protists) occur in chemosynthetic ecosystems, such as hydrothermal vents and methane seeps. However, there is little knowledge regarding protists associated with endemic animals inhabiting these environments. In the present study, utilizing PCR techniques, we detected fragments of the ...
Abecasis Ana B - - 2013
ABSTRACT: BACKGROUND: Understanding HIV-1 subtype distribution and epidemiology can assist preventive measures and clinical decisions. Sequence variation may affect antiviral drug resistance development, disease progression, evolutionary rates and transmission routes. RESULTS: We investigated the subtype distribution of HIV-1 in Europe and Israel in a representative sample of patients diagnosed between ...
Fisher Daniel Mark - - 2013
Background: Bone healing is a complex process. Whilst the majority of fractures heal with conventional treatment, open fractures, large bone defects and non unions still provide great challenges to Orthopaedic Surgeons. Whilst autologous bone graft is seen as the gold standard, the use of growth factors is a growing area ...
Zeilstra J - - 2013
A gene signature specific for intestinal stem cells (ISCs) has recently been shown to predict relapse in colorectal cancer (CRC) but the tumorigenic role of individual signature genes remains poorly defined. A prominent ISC-signature gene is the cancer stem cell marker CD44, which encodes various splice variants comprising a diverse ...
He Jianzheng - - 2013
Phrynocephalus vlangalii is a species of lizard endemic in China, which lives on Qinghai-Tibet Plateau ranging from 2000 to 4600 m above sea level. In this study, P. vlangalii were collected from low altitude (2750 m) and high altitude (4564 m). The lizards from low altitude were acclimatized in simulated hypoxic chamber (equivalent ...
Combrouse Typhaine - - 2013
AIMS: The purpose of this study was to quantify the extracellular matrix of Listeria monocytogenes biofilm. A preliminary study was carried out to establish a relationship between phylogenetic lineage of 27 strains and their ability to form biofilm in various conditions. METHODS AND RESULTS: Biofilm formation on microtiter plates of ...
Nielsen Mads C - - 2013
With the objective to increase understanding of the factors that control selectivities in high-oxidation state Palladium chemistry, we examined the chemoselectivity in the reductive elimination of a dinuclear Pd(III) complex bearing different apical ligands. Experimental, computational and spectroscopic studies were applied to understand the product selectivity derived from the mixed ...
Nagahara A - - 2013
BACKGROUND: Antimicrobial photodynamic therapy (aPDT) is a new treatment method for the removal of infectious pathogens using a photosensitizer and light of a specific wavelength, e.g., toluidine blue with a wavelength of about 600 nm. We explored a new photosensitizer and focused on indocyanine green (ICG), which has high absorption at ...
Casiraghi Mahesh - - 2013
Early event-related potential (ERP) hemispheric asymmetries recorded at occipitoparietal sites are usually observed following the sudden onset of a lateral peripheral stimulus. This is usually reflected in an onset-locked larger N1 over the posterior contralateral hemisphere relative to the ipsilateral hemisphere, an early ERP asymmetry labeled N1pc. When the peripheral ...
Sable Jeffrey J - - 2013
Previous ERP studies have provided mixed information about ADHD, especially in adults and when conscious attention to stimuli is not required. We used the auditory N1 to assess automatic attention in adults with and without ADHD. While participants watched a silent video, trains of 5 tones (400-ms onset-to-onset time) were ...
Tilak Anup R - - 2013
The causes of lung cancer might be many, but genetic variation in the genes of carcinogen-metabolizing enzymes, tumor suppressor proteins, and/or DNA-repairing enzymes can also play a significant role in lung cancer susceptibility. The tumor suppressor protein p53 functions to induce cell cycle arrest, DNA repair, or apoptosis. Polymorphism in ...
Quintão-Teixeira Luciano José - - 2013
  Peroxidase activity accounts for quality losses in many plant-based foods. The paper provides insight into the inactivation kinetics of peroxidase (POD) in carrot juice treated with pulsed electric fields (PEF). Juice samples were subjected to electric field intensities of 20 to 35 kV/cm for 300 to 2000 μs. Up ...
Batten W M J - - 2013
The actuator disc-RANS model has widely been used in wind and tidal energy to predict the wake of a horizontal axis turbine. The model is appropriate where large-scale effects of the turbine on a flow are of interest, for example, when considering environmental impacts, or arrays of devices. The accuracy ...
Liu Jing - - 2013
A new fluorescent sensor based on the BODIPY fluorophore and the polyamide receptor for Pb(2+) was designed and synthesized. The sensor is highly selective for Pb(2+) over relevant competing metal ions, and sensitive to ppb levels of Pb(2+). It features the most sensitive probe to date for Pb(2+) ions in ...
Shao Qing - - 2013
Zwitterionic carboxybetaines (CBs) are ubiquitous in nature and considered promising materials for biological and chemical applications. A thorough understanding of the effect of carbon spacer length (CSL) on molecular properties is important. In this work, using molecular dynamics simulation and quantum chemical calculation, we investigated the effect of CSL on ...
Jakupcak Matthew - - 2013
Many veterans present to Veteran Affairs (VA) care intending to seek mental health treatment for symptoms of posttraumatic stress disorder (PTSD), depression, and/or alcohol misuse, yet most subsequently underutilize mental health care. This study examined the association of readiness for change with outpatient VA mental health care utilization in 104 ...
Kim Dohun - - 2013
Introduction There have been many reports of N1 node metastasis on computed tomography (CT) scan, but not on positron emission tomography (PET)-CT in nonsmall cell lung cancer. The aim of this study was to analyze the clinicopathologic correlation and survival of N1 disease on preoperative PET-CT.Methods From January 2003 to December 2007, ...
Glover Scott - - 2013
Motor imagery may use the same mental representations as overt actions, or it may be performed using a nonmotoric cognitive estimation strategy. These competing hypotheses were tested by having participants perform either simple overt pointing tasks or analogous motor imagery tasks while manipulating the visual context and the availability of ...
Salchow Daniel J - - 2013
Purpose: To investigate the effect of spherical contact lens (CL) power on optical coherence tomography (OCT) measurements of optic nerve head (ONH) parameters in healthy subjects. Methods: Fifteen subjects without ocular disease underwent ONH analysis using OCT. Measurements were obtained without and with soft CL of different spherical powers (-10 ...
Ruiz J R - - 2013
The aim of the present case-control study was to examine the association of the ACTN3 R577X genotype with elite swimming status. We compared a group of Spanish (Caucasian) elite swimmers (n = 88) with other cohorts of the same ethnic origin, i.e., nonathletic controls (n = 343) and other types of athletes who are ...
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