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Hubbard Timothy L - - 2013
Memory for the initial pitch of an auditory target that increased or decreased in auditory frequency was examined. Memory was displaced forward in the direction of pitch motion, and this is consistent with the Fröhlich effect previously observed for visual targets moving in visual physical space. The Fröhlich effect for ...
Booth Jodie - - 2013
This paper aims to fill a gap in existing literature by using examples of reflective practice and how these informed service delivery and development with First Australians within a population health paradigm. Population-based approaches have been proposed as useful for providing services that reach beyond the individual. They may be ...
Papisov Mikhail I - - 2013
Presently, there are no effective treatments for several diseases involving the CNS, which is protected by the blood-brain, blood-CSF and blood-arachnoid barriers. Traversing any of these barriers is difficult, especially for macromolecular drugs and particulates. However, there is significant experimental evidence that large molecules can be delivered to the CNS ...
Karsten Richard - - 2013
Theories of in-stream turbines are adapted to analyse the potential electricity generation and impact of turbine arrays deployed in Minas Passage, Bay of Fundy. Linear momentum actuator disc theory (LMADT) is combined with a theory that calculates the flux through the passage to determine both the turbine power and the ...
Vidal Silvia - - 2013
PURPOSE: The aim of this study is to determine the reliability of corneal thickness measurements derived from SOCT Copernicus HR (Fourier domain OCT). METHODS: Thirty healthy eyes of 30 subjects were evaluated. One eye of each patient was chosen randomly. Images were obtained of the central (up to 2.0 mm from ...
Bogason Einar T - - 2013
BACKGROUND AND PURPOSE: Posterior cerebral artery aneurysms are treatment challenge for the neurosurgeon. Parent artery occlusion, trapping and bypass have been the classic treatment options for aneurysms in this location. With the introduction of newer embolic agents such as Onyx®, endovascular intervention is now a viable therapy for these aneurysms. ...
Boato Francesco - - 2013
ABSTRACT: Precise crosstalk between the nervous and immune systems is important for neuroprotection and axon plasticity after injury. Recently, we demonstrated that IL-1beta acts as a potent inducer of neurite outgrowth from organotypic brain slices in vitro, suggesting a potential function of IL-1beta in axonal plasticity. Here, we have investigated ...
Tsou Chih-Chin - - 2013
A reversible redox reaction ({Fe(NO)(2)}(9) DNIC [(NO)(2)Fe(N(Mes)(TMS))(2)](-) (4) ⇄ oxidized-form DNIC [(NO)(2)Fe(N(Mes)(TMS))(2)] (5) (Mes = mesityl, TMS = trimethylsilane)), characterized by IR, UV-vis, (1)H/(15)N NMR, SQUID, XAS, single-crystal X-ray structure, and DFT calculation, was demonstrated. The electronic structure of the oxidized-form DNIC 5 (S(total) = 0) may be best described ...
Shobha Nandavar - - 2013
BACKGROUND: We sought to assess the hypothesis that length and volumes of middle cerebral artery (MCA) thrombus were associated with disappearance of the hyperdense middle cerebral artery sign (HMCAS) in acute ischemic stroke. METHODS: This is a retrospective cohort study of acute ischemic stroke patients with MCA occlusion admitted to ...
Adams Denise - - 2013
OBJECTIVE:Complementary and alternative medicine (CAM) use is high among children and youth with chronic illnesses. The objective of this study was to assess the prevalence and patterns of CAM use in 10 subspecialty clinics in Canada and to compare CAM use between 2 geographically diverse locations.METHODS:This survey was carried out ...
Escudero Alberto - - 2013
Europium-doped calcium hydroxyapatite and fluoroapatite nanophosphors functionalized with poly acryl acid (PAA) have been synthesized through an one-pot microwave-assisted hydrothermal method from aqueous basic solutions containing calcium nitrate, sodium phosphate monobasic, PAA, as well as sodium fluoride in the case of the fluoroapatite particles. In both cases a spindle-like morphology ...
Sia D - - 2013
Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with very poor prognosis. Genome-wide, high-throughput technologies have made major advances in understanding the molecular basis of this disease, although important mechanisms are still unclear. Recent data have revealed specific genetic mutations (for example, KRAS, IDH1 and IDH2), epigenetic silencing, aberrant signaling pathway ...
Kawasuji Takashi - - 2013
This work is a continuation of our initial discovery of a potent monocyclic carbamoyl pyridone HIV-1 integrase inhibitor that displayed favorable antiviral and pharmacokinetic properties. We report herein a series of bicyclic carbamoyl pyridone analogs to address conformational issues from our initial SAR studies. This modification of the core unit ...
Cree Bruce Ac - - 2013
For physicians who care for patients with multiple sclerosis (MS), the use of disease-modifying therapies (DMTs) during the conception period and pregnancy raises important safety considerations. All DMTs have potential adverse effects on fertility, pregnancy outcomes, and breastfed infants. Although physicians are reluctant to prescribe DMTs to MS patients who ...
Bochatay Valentin N - - 2013
A convenient one-pot palladium-catalyzed cascade process for the preparation of both benzoxazoles and benzothiazoles has been developed. While these reactions proceed to give similar compounds the mechanisms governing the processes are different as are the experimental conditions employed.
Kładna Aleksandra - - 2013
The direct effect of the four catecholamines (adrenaline, noradrenaline, dopamine and isoproterenol) on superoxide anion radicals (O2-•) was investigated. The reaction between 18-crown-6-ether and potassium superoxide in dimethylsulfoxide was used as a source of O2-•. The reactivity of catecholamines with O2-• was examined using chemiluminescence, reduction of nitroblue tetrazolium and ...
Lagarde Pauline - - 2013
PURPOSESynovial sarcoma (SS) occurs in both children and adults, although metastatic events are much more common in adults. Whereas the importance of the t(X;18) translocation in SS oncogenesis is well established, the genetic basis of SS metastasis is still poorly understood. We recently reported expression (CINSARC; Complexity Index in Sarcoma) ...
Garcea Giuseppe - - 2013
BACKGROUND: Liver cysts are common, occurring in up to 5% of the population. For many types of cysts, a variety of different treatment options exist and the preferred management is unclear. METHODS: A PubMed and Medline literature review was undertaken and articles pertaining to the diagnosis and management of cystic ...
Schaumann Reiner - - 2013
The present study was designed to investigate the killing activity of levofloxacin, gatifloxacin, moxifloxacin, and garenoxacin against 12 Bacteroides fragilis strains by kill kinetics over time. MIC values were determined by Etest and agar dilution, respectively. B. fragilis strains were divided according to their MIC values into two groups: one ...
Ishikawa Toru - - 2013
This study empirically examined the retention of large-scale spatial memory, taking different types of spatial knowledge and levels of sense of direction into consideration. A total of 38 participants learned a route from a video and conducted spatial tasks immediately after learning the route and after 2 weeks or 3 ...
Pickering Karen - - 2013
Effective wound closure mechanisms are essential for maintenance of epithelial structure and function. The repair of wounded epithelia is primarily driven by the cells bordering the wound, which become motile after wounding, forming dynamic actin protrusions along the wound edge. The molecular mechanisms that trigger wound edge cells to become ...
Nascimento Cássio do - - 2013
OBJECTIVE: Microorganisms harboring the oral cavity, mainly those related to periodontal diseases, are the most potential etiologic factor of failure in long-term implant treatment. The material used for abutment components may influence the adhesion and colonization of microbial species. The aim of this in vivo investigation was to evaluate the ...
Mekala Naveen Kumar - - 2013
The osteogenic potential of mesenchymal stem cells (MSCs) from umbilical cord blood (UCB) on porous poly lactide-co-glycolide (PLGA) scaffolds have been reported to differentially support osteogenic differentiation based on polymer composition (80:20, 75:25 and 70:30 percent of PLA: PGA, respectively). Along with polymer composition; fused NaCl crystal matrix prior to ...
Zhao Chao - - 2013
The emergence and re-emergence of microbial infection demand an urgent need to develop effective biomaterials that prevent biofilm formation and associated bacterial infection. In this work, we have synthesized and characterized hybrid poly(n-hydroxyethylacrylamide) (polyHEAA)/salicylate (SA) hydrogels with integrated antifouling and antimicrobial capacities. The antifouling efficacy of polyHEAA hydrogels was examined ...
Nogueira Raul G - - 2013
BACKGROUND: Conventional non-invasive angiographic techniques for evaluating cerebral Arteriovenous Malformations (cAVMs) after embolization treatment are limited by their inability to acquire time-resolved images. We describe the use of dynamic contrast-enhanced magnetic resonance angiography (MRA) in the evaluation of residual arteriovenous shunting in cAVMs following Onyx embolization. METHODS: Six subjects who ...
Li H - - 2013
BACKGROUND AND OBJECTIVE: Diabetes mellitus is believed to increase the risk and severity of periodontitis. However, less evidence is available on the converse effects of periodontitis on diabetes. The objective of the study was to investigate to what degree experimental periodontitis induced by Porphyromonas gingivalis might influence the onset and ...
Hu Xiaoqing - - 2013
In an event-related potential (ERP)-based concealed information test (CIT), we investigated the effect of manipulated awareness of concealed information on the ERPs. Participants either committed a mock crime or not (guilty vs. innocent) before the CIT, and received feedback regarding either specific (high awareness) or general (low awareness) task performance ...
Grimaldi-Bensouda Lamiae - - 2013
PURPOSE: Patients' self-reported vaccine exposure (PS) may be subject to memory errors and other biases. Physicians' prescription records and other medical records (MR) do not capture noncompliance with vaccination. This study compared PS with MR for influenza, 23-valent pneumococcal, and human papillomavirus (HPV) vaccines. METHODS: The Pharmacoepidemiologic General Research Extension ...
Rusman Yudi - - 2013
During a survey of actinobacteria known to suppress the growth of Streptomyces scabies (the causative agent of potato scab disease) in vivo, six new rhamnosylated alkaloids, the solphenazines A-F (1-6), were isolated from a biological control strain of Streptomyces (DL-93). The known rhamnosyl analogue of paraben (9) was also isolated ...
Liamsuwan Thiansin - - 2013
The paper presents calculated cross sections for bare and dressed carbon projectiles of charge states q (0 to 6) with energies 1-10(4) keV u(-1) impacting on molecular water and atomic neon targets. The cross sections of water are of interest for radiobiological studies, but there are very few experimental data for water ...
Marchini Aïda Kawkabani - - 2013
BACKGROUND AND PURPOSE: Unruptured anterior inferior cerebellar artery (AICA) aneurysms are rare but potentially lethal cerebellopontine angle (CPA) lesions that may be misdiagnosed as vestibular schwannomas when they present with vestibulo-cochlear symptoms. METHODS: We report two cases of unruptured but symptomatic AICA aneurysms initially referred to us as atypical vestibular ...
Tsai H-Y - - 2013
Lung cancer is the leading cause of cancer deaths and is the most occurring malignancy worldwide. Unraveling the molecular mechanisms involved in lung tumorigenesis will greatly improve therapy. During early tumorigenesis, rapid proliferating tumor cells require increased activity of endoplasmic reticulum (ER) for protein synthesis, folding and secretion, thereby are ...
Chaudhri Anuj - - 2013
Coarse-grained computational models of therapeutic monoclonal antibodies and their mutants can be used to understand the effect of domain-level charge-charge electrostatics on the self-association phenomena at high protein concentrations. The coarse-grained models are constructed for two antibodies at different coarse-grained resolutions using six different concentrations. It is observed that a ...
Milne I A - - 2013
This paper analyses a set of velocity time histories which were obtained at a fixed point in the bottom boundary layer of a tidal stream, 5 m from the seabed, and where the mean flow reached 2.5 m s(-1). Considering two complete tidal cycles near spring tide, the streamwise turbulence intensity during non-slack ...
Woodward Amanda T - - 2013
BACKGROUND: Previous epidemiological and clinical research on mental disorders has treated Blacks as a homogenous group and yet Blacks of Caribbean descent and African Americans differ with respect to ethnicity, national heritage, living circumstances, and immigration status. The purpose of this article is to examine the prevalence of major depressive ...
Sudfeld Christopher R - - 2013
Background. Prospective studies of serum albumin as a low-cost predictor of HIV progression are needed for individuals initiating ART in resource-limited settings.Methods. Serum albumin was measured at ART initiation for 2,145 adults enrolled in a trial of multivitamins in Tanzania. Participants were prospectively followed for mortality, morbidity, and anthropometric outcomes at monthly ...
Tanaka K - - 2013
BACKGROUND AND OBJECTIVE: Studies reporting on the association between smoking and periodontal disease have mostly focused on active smoking. The purpose of this study was to examine the relationships between active smoking and exposure to second-hand smoke at home and at work and the prevalence of periodontal disease among young ...
Bachman Jerald G - - 2013
High school students who spend long hours in paid employment during the school year are at increased risk of lower grades and higher substance use, although questions remain about whether these linkages reflect causation or prior differences (selection effects). Questions also remain about whether such associations vary by socioeconomic status ...
Promislow Steven - - 2013
ABSTRACT: BACKGROUND: Previous studies have demonstrated Aboriginals are less likely to receive a renal transplant in comparison to Caucasians however whether this applies to the entire population or specific subsets remains unclear. We examined the effect of age on renal transplantation in Aboriginals. METHODS: Data on 30,688 dialysis (Aboriginal 2,361, ...
Noguchi Fumiya - - 2013
It has recently been unveiled that a wide variety of microbial eukaryotes (protists) occur in chemosynthetic ecosystems, such as hydrothermal vents and methane seeps. However, there is little knowledge regarding protists associated with endemic animals inhabiting these environments. In the present study, utilizing PCR techniques, we detected fragments of the ...
Okuno Yusuke - - 2013
We identified CD8(+) CD122(+) regulatory T cells (CD8(+) CD122(+) Tregs) and reported their importance in maintaining immune homeostasis. The absence of CD8(+) CD122(+) Tregs has been shown to lead to severe systemic autoimmunity in several mouse models, including inflammatory bowel diseases (IBD) and experimental autoimmune encephalomyelitis (EAE). The T-cell receptors ...
Abecasis Ana B - - 2013
ABSTRACT: BACKGROUND: Understanding HIV-1 subtype distribution and epidemiology can assist preventive measures and clinical decisions. Sequence variation may affect antiviral drug resistance development, disease progression, evolutionary rates and transmission routes. RESULTS: We investigated the subtype distribution of HIV-1 in Europe and Israel in a representative sample of patients diagnosed between ...
Fisher Daniel Mark - - 2013
Background: Bone healing is a complex process. Whilst the majority of fractures heal with conventional treatment, open fractures, large bone defects and non unions still provide great challenges to Orthopaedic Surgeons. Whilst autologous bone graft is seen as the gold standard, the use of growth factors is a growing area ...
Zeilstra J - - 2013
A gene signature specific for intestinal stem cells (ISCs) has recently been shown to predict relapse in colorectal cancer (CRC) but the tumorigenic role of individual signature genes remains poorly defined. A prominent ISC-signature gene is the cancer stem cell marker CD44, which encodes various splice variants comprising a diverse ...
He Jianzheng - - 2013
Phrynocephalus vlangalii is a species of lizard endemic in China, which lives on Qinghai-Tibet Plateau ranging from 2000 to 4600 m above sea level. In this study, P. vlangalii were collected from low altitude (2750 m) and high altitude (4564 m). The lizards from low altitude were acclimatized in simulated hypoxic chamber (equivalent ...
Combrouse Typhaine - - 2013
AIMS: The purpose of this study was to quantify the extracellular matrix of Listeria monocytogenes biofilm. A preliminary study was carried out to establish a relationship between phylogenetic lineage of 27 strains and their ability to form biofilm in various conditions. METHODS AND RESULTS: Biofilm formation on microtiter plates of ...
Nielsen Mads C - - 2013
With the objective to increase understanding of the factors that control selectivities in high-oxidation state Palladium chemistry, we examined the chemoselectivity in the reductive elimination of a dinuclear Pd(III) complex bearing different apical ligands. Experimental, computational and spectroscopic studies were applied to understand the product selectivity derived from the mixed ...
Nagahara A - - 2013
BACKGROUND: Antimicrobial photodynamic therapy (aPDT) is a new treatment method for the removal of infectious pathogens using a photosensitizer and light of a specific wavelength, e.g., toluidine blue with a wavelength of about 600 nm. We explored a new photosensitizer and focused on indocyanine green (ICG), which has high absorption at ...
Casiraghi Mahesh - - 2013
Early event-related potential (ERP) hemispheric asymmetries recorded at occipitoparietal sites are usually observed following the sudden onset of a lateral peripheral stimulus. This is usually reflected in an onset-locked larger N1 over the posterior contralateral hemisphere relative to the ipsilateral hemisphere, an early ERP asymmetry labeled N1pc. When the peripheral ...
Sable Jeffrey J - - 2013
Previous ERP studies have provided mixed information about ADHD, especially in adults and when conscious attention to stimuli is not required. We used the auditory N1 to assess automatic attention in adults with and without ADHD. While participants watched a silent video, trains of 5 tones (400-ms onset-to-onset time) were ...
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