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Results 551 - 600 of 2924
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Kuroda Toshikazu - - 2013
Key pecking of 4 pigeons was studied under a two-component multiple schedule in which food deliveries were arranged according to a fixed and a variable interfood interval. The percentage of response-dependent food in each component was varied, first in ascending (0, 10, 30, 70 and 100%) and then in descending ...
Wang Yangyang - - 2013
Rheological measurement was employed to study the mutarotation of D-fructose in anhydrous state. By monitoring the evolution of shear viscosity with time, rate constants for mutarotation were estimated and two different stages of this reaction were identified. One of the mutarotation stages is rapid and has a low activation energy, ...
Hasegawa Eiichi - - 2013
Choroidal neovascularization (CNV) is a characteristic of age-related macular degeneration. Genome-wide association studies have provided evidence that the immune system is involved in the pathogenesis of age-related macular degeneration; however, the role of inflammatory cytokines in CNV has not been established. In this study, we demonstrated that IL-17 had a ...
Agarwal J - - 2013
Neurological deterioration in a child following routine surgery, although rare, has potentially life threatening consequences. We report the case of a child who, following adentonsillectomy, developed quadriplegia and acute respiratory distress due to previously undetected atlanto-axial instability. Patients with atlanto-axial instability often have mild or non-specific symptoms, despite severe cervical ...
Bhalla Vandana - - 2013
Pentacenequinone derivative 3 forms luminescent supramolecular aggregates both in bulk as well as in solution phase. In bulk phase at high temperature, long range stacking of columns leads to formation of stable and ordered columnar mesophase. Further, derivative 3 works as sensitive chemosensor for picric acid (PA) and gel coated ...
Zhang Chen - - 2013
Delayed wound healing in many chronic wounds has been linked to the degradation of fibronectin (FN) by abnormally high protease levels. We sought to develop a proteolytically stable and functionally active form of FN. For this purpose, we conjugated 3.35 kDa polyethylene glycol diacrylate (PEGDA) to human plasma fibronectin (HPFN). ...
Liu Chan-Min - - 2013
Sesamin (Ses), one of the major lignan in sesame seeds and oil, has been reported to have many benefits and medicinal properties. However, its protective effects against nickel (Ni) induced injury in liver have not been clarified. The aim of the present study was to investigate the effects of sesamin ...
Yiou Pan - - 2013
Protein sample preparation is a crucial step in a 2-DE proteomics approach. In order to establish a routine protocol for the application of proteomics analysis to aphids, this study focuses on the specific protein extraction problems in insect tissues and evaluates four methods to bypass them. The approaches of phenol ...
Brader Peter - - 2013
Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging can provide noninvasive assessments of endogenous biologic processes in living subjects and can be performed using different imaging modalities. This review will focus on radionuclide-based reporter gene imaging as developed and applied in preclinical and clinical studies. Examples ...
Talipov Marat R - - 2013
There is currently great interest in S-nitrosothiols (RSNOs) because the formation of protein-based RSNOs--protein S-nitrosation--has been recently recognized as a major pathway of the biological function of nitric oxide, NO. Despite the growing number of S-nitrosated proteins identified in vivo, enzymatic processes that control reactions of biological RSNOs are still ...
Schmidt Klaus-Helmut - - 2013
AIMS: To examine the role of two personal resources (active, problem-focused coping; self-efficacy beliefs) in the relation between job demands and strain. BACKGROUND: Evidence suggests that healthcare staff in general and nurses in particular, are at a high risk of suffering from high levels of job strain. In addition to ...
Qin Xin-Min - - 2013
Here, we sequenced the complete mitochondrial genome of Spilornis cheela (Falconiformes, Accipitridae), which is considered as endemic raptor species and listed in the second category of National Key Protected Wild Animals in China. The genome is 18,291 bp in size. Its gene arrangement pattern was identical with that of Spizaetus alboniger. ...
Gomes Tara - - 2013
BACKGROUND Use of opioids may predispose drivers to road trauma, yet the effect of opioid dose on this association is unknown. METHODS We conducted a population-based nested case-control study of patients aged 18 to 64 years who received at least 1 publicly funded prescription for an opioid from April 1, ...
Ast Sandra - - 2013
In a systematic approach we synthesized a new series of fluorescent probes incorporating donor-acceptor (D-A) substituted 1,2,3-triazoles as conjugative π-linkers between the alkali metal ion receptor N-phenylaza-[18]crown-6 and different fluorophoric groups with different electron-acceptor properties (4-naphthalimide, meso-phenyl-BODIPY and 9-anthracene) and investigated their performance in organic and aqueous environments (physiological conditions). ...
Chambers Jon - - 2013
ABSTRACT: UniChem is a freely available compound identifier mapping service on the internet, designed to optimize the efficiency with which structure-based hyperlinks may be built and maintained between chemistry-based resources. In the past, the creation and maintenance of such links at EMBL-EBI, where several chemistry-based resources exist, has required independent ...
Surekha K L - - 2013
Angiogenesis, the expansion of a capillary network, is implicated in several pathological conditions. Drug-based inhibition of angiogenesis is being explored as therapy. Conversely, therapeutic angiogenesis contributes to control conditions such as ischemia. Here we report pro-angiogenic activity of perivitelline fluid (PVF) from Indian horseshoe crab embryos and one of its ...
Medd P G - - 2013
Myeloablative allo-SCT decreases relapse incidence (RI) in ALL. Reduced intensity conditioning (RIC) may extend allo-SCT to older and less fit patients. Sixty-nine ALL patients reported to the BSBMT underwent fludarabine-based RIC allo-SCT, 38 from unrelated donors (UD). Forty-four patients received alemtuzumab. ALL was in CR in 64 patients (93%). This ...
Davis Andrew Mark - - 2013
The pharmaceutical industry is in a period of intense change. While this has many drivers, attrition though the development process continues to be an important pressure. The emerging definitions of "compound quality" that are based on retrospective analyses of developmental attrition have highlighted a new direction for medicinal chemistry and ...
Depasquale Nicole - - 2013
ABSTRACT: BACKGROUND: Little is known regarding the types of information African American and non-African American patients with chronic kidney disease (CKD) and their families need to inform renal replacement therapy (RRT) decisions. METHODS: In 20 structured group interviews, we elicited views of African American and non-African American patients with CKD ...
Delesalle Marie-Aurélie - - 2013
Purpose:To determine the energy levels that provide optimal imaging of thoracic circulation at dual-energy computed tomographic (CT) angiography with reduced iodine load in comparison with a standard technique.Materials and Methods:The institutional review board approved the study with waiver of patient consent. Eighty patients underwent a dual-source, dual-energy CT examination after ...
Hajimiragha Habib - - 2013
Abstract Purpose: The present study was done to evaluate the effects of different types of abutments on the rate and distribution of stress on the bone surrounding the implant by dynamic finite element analysis method.Material and methods: In this study two ITI abutment models, one-piece and multi-piece, along with fixture, ...
Inzelberg Rivka - - 2013
Despite the prominent loss of motor skills, artistic capacities remain preserved in Parkinson's disease (PD). Furthermore, artistic creativity may emerge in art-naïve PD patients treated with levodopa and dopamine agonists. The present review discusses reported PD patients who developed enhanced artistic skills under anti-Parkinsonian therapy and the course of this ...
Fülesdi Béla - - 2013
BACKGROUND AND PURPOSE: The hematoma volume is an important determinant of outcome and a predictor of clinical deterioration in patients with intracerebral hemorrhage (ICH). Our goal was to evaluate alterations in the cerebral circulation, in respect to hemorrhage and edema volume changes, using transcranial Doppler (TCD). METHODS: Twenty patients with ...
Trajkovski Suza - - 2013
AIM: To examine and critique how the phases of the 4D cycle (Discovery, Dream, Design, and Destiny) of appreciative inquiry are implemented in a healthcare context. BACKGROUND: Appreciative inquiry is a theoretical research perspective, an emerging research methodology and a world view that builds on action research, organizational learning, and ...
Nishi M - - 2013
Cancer stem cells (CSCs), a small and elusive population of undifferentiated cancer cells within tumors that drive tumor growth and recurrence, are believed to resemble normal stem cells. Although surrogate markers have been identified and compelling CSC theoretical models abound, actual proof for the existence of CSCs can only be ...
Draper S - - 2013
Enhanced tidal streams close to coastal headlands appear to present ideal locations for the deployment of tidal energy devices. In this paper, the power potential of tidal streams near an idealized coastal headland with a sloping seabed is investigated using a near-field approximation to represent a tidal fence, i.e. a ...
Knope M L - - 2013
Sculpin fishes of the North American Pacific Coast provide an ideal opportunity to examine whether adaptive morphological character shifts have facilitated occupation of novel habitat types because of their well-described phylogeny and ecology. In this group, the basal-rooted species primarily occupy the subtidal habitat, whereas the species in the most ...
Chan D S Y - - 2013
BACKGROUND: The prognostic role and definition of circumferential resection margin (CRM) involvement in operable oesophageal cancer remain controversial. The College of American Pathologists (CAP) and Royal College of Pathologists (RCP) define CRM involvement as tumour found at the cut resection margin and within 1 mm of the cut margin respectively. ...
Smeets-Janssen M M J - - 2013
OBJECTIVE: Theory of Mind (ToM) is considered an essential element of social cognition. In younger schizophrenia patients, ToM impairments have extensively been demonstrated. It is not clear whether similar impairments can be found in older schizophrenia patients and if these impairments differ between older patients with early-onset and late-onset schizophrenia. ...
Chiang Tzen-Yuh - - 2013
In this study, we sequenced the complete mitochondrial genome of Sicyopterus japonicus (Perciformes, Gobiidae). This mitochondrial genome consists of 16,514 base pairs (bp), with 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes, and 1 non-coding control region (CR), also with the gene synteny identical to that of ...
Manri Naomi - - 2013
We developed a liquid chromatography (LC) compatible electron capture dissociation (ECD) mass spectrometer for glycoproteomics, with which ECD and hot ECD (HECD) experiments can be flexibly switched by quickly changing the electron energy without further tuning of the mass spectrometer. Desialylated glycopeptides were dissociated well in both ECD and HECD ...
Duijf P H G - - 2013
One form of chromosome instability (CIN), the recurrent missegregation of whole chromosomes during cell division (W-CIN), leads to aneuploidy. Although W-CIN is a hallmark of most cancers, mutations in genes involved in chromosome segregation are exceedingly rare. We discuss an oncogene-induced mitotic stress model that provides a mechanistic framework to ...
Fujita Shigeru - - 2013
ABSTRACT: BACKGROUND: Quality and safety issues are receiving growing attention. Patient safety culture (PSC) plays an important role in patient safety. The characteristics of PSC in various countries, each with a different set of values, have not been determined sufficiently. The aim of this study is to investigate the characteristics ...
Treno Andrew J - - 2013
BACKGROUND: Alcohol beverage prices or taxes have been shown to be related to alcohol sales and use and related problems. What is not clear are the mechanisms underlying these relationships. METHODS: This study examines the relationship between alcohol outlet density under conditions of the partial privatization of off-premise consumption in ...
Akhavan-Sigari Reza - - 2013
Background Toxic epidermal necrolysis (TEN) is a rare, severe adverse drug reaction. Steven-Johnson syndrome (SJS) represents the milder end of the spectrum. The exact pathogenesis of TEN and SJS is still unknown. Many drugs, including prednisolone, cyclosporin, and intravenous immunoglobulin (IVIG), have been used in an attempt to halt the disease ...
Chiu Yu-Chin - - 2013
Much research on response inhibition has focused on a consciously triggered variety (i.e., outright stopping of action). However, recent studies have shown that response inhibition can also be triggered unconsciously. For example, van Gaal, Ridderinkhof, Scholte, and Lamme (2010) showed that an unconscious no-go prime slowed down ongoing behavior, at ...
Wu Weiwei - - 2013
During sleep, the brain network processes sensory stimuli without awareness. Stimulation must affect differently brain networks in sleep versus wake, but these differences have yet to be quantified. We recorded cortical activity in stage 2 (SII) sleep and wake using EEG while a tone was intermittently played. Zero-lag correlation measured ...
O'Mahen Heather - - 2013
BACKGROUND: Perinatal women with identified depression in prenatal care settings have low rates of engagement and adherence with depression-specific psychotherapy. We report the feasibility and symptom outcomes of Cognitive Behavioral Therapy (CBT) modified (mCBT) to address the needs of perinatal, low-income women with Major Depressive Disorder (MDD). METHODS: Pregnant women ...
Gutierrez Jose - - 2013
BACKGROUND AND PURPOSE: Dolichoectasia (DE) is a vasculopathy that consists of abnormal elongation and dilatation of arteries. The objective of this study is to evaluate the frequency of DE in an unselected population and assess different diagnostic methods. METHODS: The Northern Manhattan Study is a multiethnic population based cohort of ...
Connolly Gregory C - - 2013
ABSTRACT: BACKGROUND: Diabetes mellitus (DM) is identified as a negative prognostic indicator in hepatocellular carcinoma (HCC), though the basis for this is unknown. METHODS: This is a retrospective analysis of a prospectively collected database of 191 HCC patients treated at the University of Rochester Medical Center (URMC) with orthotopic liver ...
Eickenberg Bernhard - - 2013
Under the influence of homogeneous, rotating magnetic fields, superparamagnetic beads can be assembled into one- and two-dimensional superstructures on demand and used as dynamic components in microfluidic systems for colloidal separation. In this paper, the influence of the magnetic field strength and the rotation frequency on the device efficiency is ...
Jackson Lisa A - - 2013
OBJECTIVE:Our objective was to assess whether the occurrence of medically attended local reactions to intramuscularly administered vaccines varies by injection site (arm versus thigh) in children 1 to 6 years of age.METHODS:This is a retrospective cohort study of children in the Vaccine Safety Datalink population from 2002 to 2009. Site ...
Chauvin C - - 2013
S6 kinases (S6Ks) are mechanistic target of rapamycin substrates that participate in cell growth control. S6Ks phosphorylate ribosomal protein S6 (rpS6) and additional proteins involved in the translational machinery, although the functional roles of these modifications remain elusive. Here we analyze the S6K-dependent transcriptional and translational regulation of gene expression ...
Akarsu Saadet - - 2013
BACKGROUND: In this study the effects of the iron deficiency anemia (IDA) and its treatment on plasma total antioxidant capacity (TAOC) were investigated. METHODS: Eighty patients with IDA and the healthy control group form were divided into four subgroups as (oral [PO] group [n: 20], intramusculer [IM] group [n: 20], ...
Yoshikawa Momoko - - 2013
The targeting of antioxidant systems that allow stem-like cancer cells to avoid the adverse consequences of oxidative stress might be expected to improve the efficacy of cancer treatment. Here we show that head and neck squamous cell carcinoma (HNSCC) cells that express variant isoforms of CD44 (CD44v) rely on the ...
Pieragostino Damiana - - 2013
Transthyretin (TTR) is an homotetrameric protein of the Central Nervous System (CNS) that plays the role of the major Thyroxine (T4) carrier from blood to Cerebrospinal Fluid (CSF). T4 physiologically helps oligodendrocyte precursor cells to turn into myelinating oligodendrocytes, enhancing remyelination after myelin sheet damage. We investigated post-translational oxidative modifications ...
Hubbard Timothy L - - 2013
Memory for the initial pitch of an auditory target that increased or decreased in auditory frequency was examined. Memory was displaced forward in the direction of pitch motion, and this is consistent with the Fröhlich effect previously observed for visual targets moving in visual physical space. The Fröhlich effect for ...
Booth Jodie - - 2013
This paper aims to fill a gap in existing literature by using examples of reflective practice and how these informed service delivery and development with First Australians within a population health paradigm. Population-based approaches have been proposed as useful for providing services that reach beyond the individual. They may be ...
Karsten Richard - - 2013
Theories of in-stream turbines are adapted to analyse the potential electricity generation and impact of turbine arrays deployed in Minas Passage, Bay of Fundy. Linear momentum actuator disc theory (LMADT) is combined with a theory that calculates the flux through the passage to determine both the turbine power and the ...
Vidal Silvia - - 2013
PURPOSE: The aim of this study is to determine the reliability of corneal thickness measurements derived from SOCT Copernicus HR (Fourier domain OCT). METHODS: Thirty healthy eyes of 30 subjects were evaluated. One eye of each patient was chosen randomly. Images were obtained of the central (up to 2.0 mm from ...
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