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Results 451 - 500 of 2977
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Borges Maria Carolina - - 2013
This study investigated the effects of mate tea (Ilex paraguariensis) aqueous extract consumption on metabolic indicators and inflammatory response of peritoneal macrophages in rats fed a high-fat diet (HFD). Male Wistar rats were fed a control diet or a HFD for 12 weeks. At the end of this period, rats ...
Chávez-Munguía Bibiana - - 2013
During Acanthamoeba castellanii trophozoite-cysts differentiation, four morphological stages were identified by scanning electron microscopy: trophozoite, precyst, immature cysts, and mature cysts. Fluorescence microscopy reveals the presence of small cumulus of actin in the cytoplasm of precysts after treatment with rhodamine phalloidin. By the contrary, in mature cysts, fluorescence was not ...
Street J T - - 2013
Study Design:Observational cohort comparison.Objectives:To compare the previously validated Spine Adverse Events Severity system (SAVES) with International Classification of Diseases, Tenth Revision codes (ICD-10) codes for identifying adverse events (AEs) in patients with traumatic spinal cord injury (TSCI).Setting:Quaternary Care Spine Program.Methods:Patients discharged between 2006 and 2010 were identified from our prospective ...
Capoccia Victor - - 2013
OBJECTIVE: Since 2008 Massachusetts has had universal health insurance with an individual mandate. As a result, only about 3% of the population is uninsured. However, patients who use behavioral health services are uninsured at much higher rates. This 2011 study sought to understand reasons for the discrepancy and identify approaches ...
Batuecas-Caletrio Angel - - 2013
Abstract Conclusions: The degree of caloric weakness before surgery influences faster or slower recovery of patients undergoing vestibular schwannoma surgery. The Dizziness Handicap Inventory (DHI) is a good index to show the recovery of patients as it relates directly to an improvement or not of the subjective visual vertical (SVV). ...
Glass A S AS Department of Urology, University of California, San Francisco, CA 94143-1695, USA. - - 2013
Active surveillance (AS) is an appropriate management strategy for men with low-risk prostate cancer. Most protocols recommend repeated prostate biopsy every 12-24 months. The purpose of this paper is to describe histological inflammation patterns in men on AS who underwent serial prostate biopsy for disease monitoring. We reviewed records of ...
Hoar Sarah - - 2013
In the present study, we used Navon-type Cognitive Psychology 9: 353-383 (1977) hierarchical patterns to demonstrate that cognitive load eliminates a global perceptual bias and enhances the representation of local elements at unlimited exposure durations. We added a cognitive-load manipulation to Kimchi and Palmer's Journal of Experimental Psychology: Human Perception ...
Schectman Joel M - - 2013
QUESTION What is the efficacy of interventions to improve patient transition from hospital discharge to primary care? REVIEW SCOPE Included studies involved patients ≥ 18 years of age and care providers during the transition of care from hospital to primary care or home care; assessed interventions with ≥ 1 component aimed at ...
Taherian Nassim N Department of Medical Genetics, Research Institute of McGill University Health Centre, Montreal, QC H3G 1A4, - - 2013
A 51-year-old French Canadian man presented to his family physician owing to an extensive family history of prostate cancer in five brothers, his father and two paternal uncles. His serum PSA level was 4.9 ng/ml and a six-core biopsy revealed the presence of a prostate adenocarcinoma with a Gleason score ...
Tamiya Hiroko - - 2013
Abstract S-adenosyl-L-methionine (SAM) is an intermediate metabolite of methionine and serves as the methyl donor for many biological methylation reactions. The synthesis of SAM is catalyzed by SAM synthetase (SAMS), which transfers the adenosyl moiety of adenosine-5'-triphosphate to methionine. In the nematode Caenorhabditis elegans, four sams family genes, sams-1, -3, ...
Rozenberg Perri - - 2013
Mortalin/GRP75 is a ubiquitous mitochondrial chaperone related to the cytosolic heat shock protein 70 (HSP70). It protects cells from senescence and apoptosis and is overexpressed in cancer cells. Cell resistance to complement-dependent cytotoxicity depends on mortalin and during complement attack mortalin is released from cells. Our goal was to determine ...
Dong Ban Xuan - - 2013
Hybrid materials composed of phase-separated block copolymer films and conjugated polymers of the phenylenevinylene family (PPV) are prepared. The PPV chains are embedded in vertical cylinders of nanometer diameter in the block-copolymer films. The cylinders span continuously the whole film thickness of 70 nm. Incorporation of the PPV chains into ...
Wan Osanna Y K - - 2013
AIMS: To evaluate the risk of missing a malignancy in surgical specimens following hysterectomy for uterine prolapse if routine pathological examination is not performed. Additionally, information on the risk of missing an hitherto unsuspected malignancy if uterine preservation is the preferred management option will be provided. MATERIALS AND METHODS: A ...
Dekel Roy - - 2013
Irritable bowel syndrome (IBS), the most common functional gastrointestinal disorder, is manifested by chronic abdominal pain associated with irregular bowel movements. Although not life threatening, IBS is associated with impaired quality of life that ranges from mild to severe. The pathogenesis of IBS is not completely understood, but involves dysfunction ...
Vanheel Hanne - - 2013
Functional dyspepsia is an extremely common disorder of gastrointestinal function. The disorder is thought to be heterogeneous, with different pathophysiological mechanisms underlying varied symptom patterns. A diversity of changes in gastrointestinal tract function and structure has been described in functional dyspepsia. These involve alterations in the stomach, such as impaired ...
Vozdova Miluse M Department of Genetics and Reproduction, Veterinary Research Institute, Hudcova 70, Brno, Czech Republic. - - 2013
To analyse relationships between semen parameters, sperm chromatin integrity and frequencies of chromosomally unbalanced, disomic and diploid sperm in 13 Robertsonian and 37 reciprocal translocation carriers and to compare the results with data from 10 control donors. Conventional semen analysis, Sperm Chromatin Structure Assay and FISH with probes for chromosomes ...
Shin Jin Hee - - 2013
BACKGROUND: Patients undergoing laparoscopic Roux-en-Y gastric bypass (LRYGB) often have substantial comorbidities, which must be taken into account to appropriately assess expected postoperative outcomes. The Charlson/Deyo and Elixhauser indices are widely used comorbidity measures, both of which also have revised algorithms based on enhanced ICD-9-CM coding. It is currently unclear ...
Dutton G R - - 2013
Objective:The relationship between obesity and suicidal ideation and behavior (suicidality) is not well understood, and conventional suicide risk factors do not adequately explain the associations observed. Thus, the current study aimed to further examine the relationship between body mass index (BMI; kg m(-2)) and suicidal ideation as well as potential mechanisms ...
Tsintzas Kostas - - 2013
Physiological hyperglycaemia and hyperinsulinaemia are strong modulators of gene expression, which underpins some of their well known effects on insulin action and energy metabolism. The aim of this study was to examine whether acute in vivo exposure of healthy humans to hyperinsulinaemia and hyperglycaemia have independent or additive effects on ...
Vivian Diana D Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, - - 2013
To synthesize a trifluorinated bile acid that can be used for (19)F magnetic resonance imaging (MRI) of bile acid enterohepatic circulation, characterize its in vitro transporter affinity, stability, and (19)F-MRI signal, and assess its ability to concentrate in the gallbladder of C57BL/6 mice. Target compound CA-lys-TFA was synthesized and tested ...
Wang X - - 2013
BACKGROUND: Several node staging schemes have been proposed for gastric cancer. The optimal system remains controversial. METHODS: Patients with gastric cancer were identified from the Surveillance, Epidemiology, and End Results (SEER) database, and a Chinese patient cohort was used for independent validation. The prognostic performance of three node staging schemes ...
Zhang Huisheng - - 2013
Protein S100B is a clinically useful non-invasive biomarker for brain cell damage. A rapid chemiluminescence immunoassay (CLIA) for S100B in human serum has been developed. Fluorescein isothiocyanate (FITC) and N-(aminobutyl)-N-(ethylisoluminol) (ABEI) are used to label two different monoclonal antibodies of anti-S100B. Protein S100B in serum combines with labeled antibodies and ...
Moreno-Navarrete J M - - 2013
Objective:Recent studies linked circulating pigment epithelium-derived factor (PEDF) to obesity-associated insulin resistance, but the main source of circulating PEDF is unknown. We aimed to investigate liver and adipose tissue PEDF gene expression in association with obesity and insulin resistance.Design, subjects and methods:Three (two cross-sectional and one longitudinal) independent cohorts have ...
Thomas de Montpréville Vincent - - 2013
Thymic carcinomas represent the rarest and the more aggressive form of thymic epithelial tumors. We retrospectively reviewed a series of 37 consecutive cases seen in our hospital over a 15-year period. The patient group consisted of 14 female and 23 male patients, aged 31 to 80 years (mean = 57). Nineteen patients were ...
Rajan Roopa - - 2013
A 27-year-old man, recent visitor to the Middle East, presented with 6-week history of fever (up to 102°F) followed by altered behavior and left hemiparesis. CSF was acellular with raised protein (138 mg/dL). CSF bacterial culture was sterile; adenosine deaminase normal (3 U/L); cryptococcal antigen, Venereal Disease Research Laboratory test, ...
Binauld Sandra - - 2013
Polymers that start degrading under acidic conditions are increasingly investigated as a pathway to trigger the release of drugs once the drug carrier reached the slightly acidic tumour environment or after the drug carrier has been taken up by cells, resulting in the localization of the polymer in the acidic ...
Nascimento Cássio do - - 2013
OBJECTIVES: The aim of this in vivo study was to evaluate the efficacy of three antimicrobial solutions on the disinfection of toothbrushes after storage in closed containers. MATERIALS AND METHODS: Sixteen healthy subjects were enroled in this randomized cross-over clinical investigation. The study was conducted in four phases, in which ...
Perrelli Maria-Giulia - - 2013
Catestatin (CST) limits myocardial ischaemia/reperfusion (I/R) injury with unknown mechanisms. Clearly phosphoinositide-3-kinase (PI3K), protein kinase C (PKC) isoforms, including intra-mitochondrial PKCε, mitochondrial K(ATP) (mitoK(ATP)) channels and subsequent reactive oxygen species (ROS)-signalling play important roles in postconditioning cardioprotection, preventing mitochondrial permeability transition pore (mPTP) opening. Therefore, we studied the role of ...
Ensaff Hannah - - 2013
OBJECTIVE: To examine students' school food choice in relation to school food standards and entitlement to free school meals (FSM). DESIGN: Cross-sectional analysis of students' school food choices. SETTING: Two large secondary schools in Yorkshire, England. SUBJECTS: Students (n 2660) aged 11-18 years. RESULTS: Sandwiches and pizza were the most ...
Shiokawa Masahiro - - 2013
OBJECTIVES:Although simultaneous occurrences of autoimmune pancreatitis (AIP) and cancer are occasionally observed, it remains largely unknown whether cancer and AIP occur independently or these disorders are interrelated. The aim of this study was to examine the relationship between AIP and cancer.METHODS:We conducted a multicenter, retrospective cohort study. One hundred and ...
Galal Ahmed - - 2013
Background. Wide-necked and non-saccular aneurysms are difficult to treat with coil embolization. The use of stents has expanded the role of endovascular treatment. Methods. A retrospective study of 43 patients with wide-necked, fusiform or blister aneurysms treated with stent-assisted coiling or stent alone. The review of medical files and images ...
Ye Xiao-Juan - - 2013
A balance between the hydrogen capacity and reversibility is a big challenge in the search for hydrogen storage materials. Using van der Waals-corrected density functional theory, we perform a detailed study of the hydrogen molecules adsorption on lithium (Li) decorated zero- and two-dimensional boron-carbon (B-C) compounds. It is found that ...
Leonard Christopher W CW Department of Chemistry, University of North Carolina, Chapel Hill, NC 27599-3290, - - 2013
Accurate RNA structure modeling is an important, incompletely solved, challenge. Single-nucleotide resolution SHAPE (selective 2'-hydroxyl acylation analyzed by primer extension) yields an experimental measurement of local nucleotide flexibility that can be incorporated as pseudo-free energy change constraints to direct secondary structure predictions. Prior work from our laboratory has emphasized both ...
Kim Jean H - - 2013
AIMS: To investigate the competing effects of increased anti-drink driving legislation and the recent elimination of excise taxes on wine and beer. DESIGN: Serial cross-sectional telephone surveys were conducted in 2006 (n=9860) and 2011 (n=4800). SETTING: Hong Kong, China. PARTICIPANTS: Chinese adults (>18 years of age). MEASUREMENTS: Respondents were asked ...
Flowers Christopher R - - 2013
PURPOSETo provide guidelines on antimicrobial prophylaxis for adult neutropenic oncology outpatients and on selection and treatment as outpatients of those with fever and neutropenia. METHODSA literature search identified relevant studies published in English. Primary outcomes included: development of fever and/or infections in afebrile neutropenic outpatients and recovery without complications and ...
Fursova N - - 2013
The novel β-lactamase gene bla(CTX-M-116) was identified in a Proteus mirabilis nosocomial isolate recovered from the urine of a patient in Moscow in 2005. DNA sequence analysis showed bla(CTX-M-116) to be a hybrid gene consisting of 5' bla(CTX-M-23) (nucleotides 1 to 278) and 3' bla(CTX-M-22) (nucleotides 286 to 876) moieties ...
Pugach Irina - - 2013
The Australian continent holds some of the earliest archaeological evidence for the expansion of modern humans out of Africa, with initial occupation at least 40,000 y ago. It is commonly assumed that Australia remained largely isolated following initial colonization, but the genetic history of Australians has not been explored in ...
Kamimura Keisuke - - 2013
Heparan sulfate proteoglycans (HSPGs) play pivotal roles in the regulation of Wnt signaling activity in several tissues. At the Drosophila melanogaster neuromuscular junction (NMJ), Wnt/Wingless (Wg) regulates the formation of both pre- and postsynaptic structures; however, the mechanism balancing such bidirectional signaling remains elusive. In this paper, we demonstrate that ...
Zhao Yu - - 2013
Two kinds of B&N codoped carbon nanotubes (CNTs) dominated by bonded or separated B and N are in-tentionally prepared, which present distinct oxygen reduc-tion reaction (ORR) performances. The experimental and theoretical results indicate that the bonded case cannot, while the separated one can, turn the inert CNTs into ORR electrocatalysts. ...
Hong L - - 2013
Excess body weight (body mass index >25 kg/m(2) ) is common in patients with esophageal adenocarcinoma. In this study, a meta-analysis was performed by searching PubMed, Cochrane Library, EMBASE, and Science Direct databases from 1960 to June 2012. Data were extracted from studies comparing survival in obese (body mass index >30), ...
Abdihalim Mohamed - - 2013
BACKGROUND: Recurrence following endovascular treatment of intracranial aneurysm is attributed to either coil compaction or aneurysm growth but these processes have not been studied as distinct processes. METHODS: The pixel size of the coil mass and aneurysm sac, and the adjacent parent artery were measured and expressed as a ratio ...
Jan Show-Li - - 2013
For one-way fixed effects ANOVA, it is well known that the conventional F test of the equality of means is not robust to unequal variances, and numerous methods have been proposed for dealing with heteroscedasticity. On the basis of extensive empirical evidence of Type I error control and power performance, ...
Teng Y Y Georgia Health Sciences University, Cancer Center, Augusta, GA, - - 2014
The WASF3 gene promotes invasion and metastasis in breast cancer cells, which have undergone epithelial-to-mesenchyme transition (EMT). Overexpression of WASF3 in cells that do not show EMT increases their invasion potential as a result of increased ZEB1/2 levels, which specifically suppress the anti-invasion chromosome 1 miR-200a/200b/429 cluster. ZEB1/2 upregulation by ...
Shoae-Hassani Alireza - - 2013
Reconstruction of the bladder wall via in vitro differentiated stem cells on an appropriate scaffold could be used in such conditions as cancer and neurogenic urinary bladder. This study aimed to examine the potential of human endometrial stem cells (EnSCs) to form urinary bladder epithelial cells (urothelium) on nanofibrous silk-collagen ...
Goyal Amit - - 2013
ABSTRACT: BACKGROUND: For patients with early breast cancer and lymph node metastasis, axillary treatment is widely recommended. This is either surgical removal of the axillary lymph nodes, or axillary radiotherapy. The rationale for axillary treatment is that it will reduce the risk of recurrence in the axilla, and may improve ...
Stein Jeffrey S JS Department of Psychology, Utah State University, 2810 Old Main Hill, Logan, UT 84322, USA. - - 2013
In both humans and nonhumans, prior research demonstrates increased preference for larger-later over smaller-sooner rewards when rewards are bundled together in a series (i.e., when an operant choice produces multiple discrete reward deliveries, as opposed to only a single delivery). These findings can be predicted using a traditional hyperbolic delay-discounting ...
Wang Yunling - - 2013
The quaking (qkI) gene encodes 3 major alternatively spliced isoforms that contain unique sequences at their C termini dictating their cellular localization. QKI-5 is predominantly nuclear, whereas QKI-6 is distributed throughout the cell and QKI-7 is cytoplasmic. The QKI isoforms are sequence-specific RNA binding proteins expressed mainly in glial cells ...
Yoshikawa Momoko - - 2013
The targeting of antioxidant systems that allow stem-like cancer cells to avoid the adverse consequences of oxidative stress might be expected to improve the efficacy of cancer treatment. Here we show that head and neck squamous cell carcinoma (HNSCC) cells that express variant isoforms of CD44 (CD44v) rely on the ...
Cordova Kristen N KN Division of Rheumatology, Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045, - - 2013
Citrullinated proteins, derived from the conversion of peptidyl-arginine to peptidyl-citrulline, are present in the joints of patients with rheumatoid arthritis (RA), who also uniquely produce high levels of anti-citrullinated protein Abs. Citrullinated fibrinogen (CF) is abundant in rheumatoid synovial tissue, and anti-citrullinated protein Ab-positive RA patients exhibit circulating immune complexes ...
Gujral Unjali P - - 2013
Type 2 diabetes mellitus (T2DM) is one of the leading causes of morbidity and mortality. While all ethnic groups are affected, the prevalence of T2DM in South Asians, both in their home countries and abroad, is extremely high and is continuing to rise rapidly. Innate biological susceptibilities coupled with rapid ...
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