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Labonté Marie-Ève - - 2013
The present randomised parallel study assessed the impact of adding MUFA to a dietary portfolio of cholesterol-lowering foods on the intravascular kinetics of apoAI- and apoB-containing lipoproteins in subjects with dyslipidaemia. A sample of sixteen men and postmenopausal women consumed a run-in stabilisation diet for 4 weeks. Subjects were then ...
Bhargava Arpit - - 2013
Aim: The work attempts to overcome tumor-associated immune tolerance using a surface-modified solid lipid nanoparticle (SLNP) delivery system for dendritic cell (DC) immunotherapy. Materials & methods: Different formulations of SLNPs (SLNPs-alone, cationic-SLNPs and mannosylated-SLNPs) were prepared using tumor cell lysates. Prepared nanoparticles were characterized and their ability to activate DCs ...
Purkait Suvendu - - 2013
Cell cycle regulator genes are major target of mutation in many human malignancies including glioblastomas (GBMs). CDKN2A is one such tumor suppressor gene which encodes p16INK4a protein and serves as an inhibitor of cell cycle progression. Very few studies are available regarding the association of CDKN2A deletion with p16 protein ...
Zhou Na - - 2013
A simple and sensitive electrochemical assay strategy of stripping voltammetry for mercury ions (Hg(2+)) detection is described based on the synergistic effect between ionic liquid functionalized graphene oxide (GO-IL) and gold nanoparticles (AuNPs). The AuNPs-GO-IL modified onto glassy carbon electrode (GCE) resulted in highly enhanced electron conductive nanostructured membrane and ...
Ferraço Renato - - 2013
Abstract Objectives: The aim of this study was to evaluate the stress distribution in mandibular free-end removable partial dentures (RPD) associated with FPD in the abutment teeth considering different inclinations of the residual ridge: (1) horizontal and (2) distal descending ridges and two designs of free-end RPD with different attachment ...
Gamal-Eldin Mona A - - 2013
The formations of host-guest complexes between cucurbit[7]uril and a series of N-substituted N-methylpiperidinium, N-methylpyrrolidinium, and N-methylmorpholinium cations in aqueous solution have been investigated using (1)H NMR spectroscopy and electrospray ionization mass spectrometry. Dications comprising the N-methylheterocyclic head groups, bridged by a decamethylene chain, form sequential 1 : 1 ([2]pseudorotaxanes) and 2 : 1 host-guest ...
Laurenius Anna - - 2013
There is a lack of prevalent data for dumping syndrome (DS) and methods discriminating between different symptoms of the DS. A self-assessment questionnaire, the Dumping Symptom Rating Scale (DSRS), was developed. The aim was to measure the severity and frequency of nine dumping symptoms and to evaluate the construct validity ...
Ivell Richard - - 2013
Maternal exposure to estrogenic xenobiotics or phthalates has been implicated in the distortion of early male reproductive development, referred to in humans as the testicular dysgenesis syndrome. It is not known, however, whether such early gestational and/or lactational exposure can influence the later adult-type Leydig cell phenotype. In this study, ...
Chen Hangjun - - 2013
ABSTRACT: BACKGROUND: The Chinese bayberry (Myrica rubra Sieb. and Zucc.) is a subtropical fruit native to China, with unique flavor, sweet and sour taste, and high nutrition and health values. The fruit is highly perishable and susceptible to mechanical injury, physiological deterioration and fungal decay once harvested. This study was ...
Hedelin Hans - - 2013
Abstract Objective. The aim of this study was to describe the prevalence of the chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) among middle-aged men in a region with a temperate climate, i.e. a community in western Sweden. Material and methods. Men aged 40-69 years who, on the basis of postal invitation, ...
Jantscher-Krenn Evelyn - - 2013
Human milk oligosaccharides (HMO) are complex glycans that are highly abundant in human milk, but not in infant formula. Accumulating data, mostly from in vitro and animal studies, indicate that HMO benefit the breast-fed infant in multiple ways and in different target organs. In vitro incubation studies suggest that HMO ...
Gomes Catarina - - 2013
Gastric cancer is preceded by a carcinogenesis pathway which includes gastritis caused by Helicobacter pylori infection, chronic atrophic gastritis that may progress to intestinal metaplasia (IM), dysplasia and ultimately gastric carcinoma of the more common intestinal subtype. The identification of glycosylation changes in circulating serum proteins in patients with precursor ...
True Nicholas A - - 2013
BACKGROUND: Patients seeking care in public hospitals are often resource-limited populations who have in past disasters become the most vulnerable. The objective of this study was to determine the personal disaster preparedness of emergency department (ED) patients and to identify predictors of low levels of preparedness. It was hypothesized that ...
Ben Nasr Nesrine - - 2013
Structure Based Virtual Ligand Screening (SBVLS) methods are widely used in drug discovery programs. When several structures of the target are available, protocols based either on single structure docking or on ensemble docking can be used. The performance of the methods depends on the structure(s) used as a reference, whose ...
Shao Jie - - 2013
In order to explore the potential application of sulfur in aqueous rechargeable batteries, core-shell sulfur-polypyrrole (S@PPy) composites were prepared through a novel one-pot and surfactant-free method. Sulfur exhibits a very high capacity of 473 mA h g(-1) and good cycling stability in an aqueous Li(2)SO(4) electrolyte due to the polypyrrole ...
Sangorrín M P - - 2013
AIMS: Dekkerabruxellensis and Pichia guilliermondii are contaminating yeasts in wine due to the production of phenolic aromas. Although the degradation pathway of cinnamic acids, precursors of these phenolic compounds has been described in D. bruxellensis, no such pathway has been described in P. guilliermondii. METHODS AND RESULTS: A molecular and ...
Dinić Svetlana - - 2013
The present study aimed to investigate the effects of the treatment with α-lipoic acid (LA), a naturally occurring compound possessing antioxidant activity, on liver oxidant stress in a rat model of streptozotocin (STZ)-induced diabetes by examining potential mechanistic points that influence changes in the expression of antioxidant enzymes such as ...
van der Zee Carlijn H - - 2013
Abstract Objective: The responsiveness of a new participation measure, the Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-Participation) was compared with that of the Impact on Particpation and Autonomy (IPA). Furthermore, the concurrent validity of these two measures was assessed. Method: Participants were patients with brain injury or neuromuscular disease, who ...
Sahin Kazim - - 2013
To evaluate the action mode of Berberis vulgaris root extract in the alleviation of oxidative stress, female Japanese quails (n 180, aged 5 weeks) were reared, either at 22°C for 24 h/d (thermoneutral, TN) or 34°C for 8 h/d (heat stress, HS), and fed one of three diets: diets containing 0, 100 ...
Sheehy C - - 2013
Objectives: Patients with rheumatoid arthritis (RA) suffer progressive loss of hand function and have weaker hand grip than the healthy population. In this study we aimed to validate hand grip strength standardized by age and gender (z score) against currently accepted clinical measures of disease activity. Method: Electronic records of ...
Xu Kailin - - 2013
A highly efficient, simple and rapid method, injection-ultrasound-assisted emulsification microextraction based on using low-density organic solvents followed by high-performance liquid chromatography-ultraviolet detection, was developed for the determination of trace level pyrethroids in water samples. Various parameters influencing the extraction efficiency, such as type of extractant, extractant volume, ultrasonic time, centrifugation ...
Nouar Roqiya - - 2013
Microtubules (MTs) are involved in many crucial processes such as cell morphogenesis, mitosis and motility. These dynamic structures resulting from the complex assembly of tubulin are tightly regulated by stabilizing microtubule-associated proteins (MAPs) such as tau and destabilizing proteins, notably stathmin. Because of their key role, these MAPs and their ...
Li Hui - - 2013
The bioresponsive detection of DNA or proteins and the controlled release of drug molecules are two important research areas for both experimental studies and practical applications. However, the real incorporation of these two functions into one system is still untouched. Being different from the widely reported mesoporous silica nanoparticles that ...
Tendais Iva - - 2013
Fetal movements and fetal heart rate (FHR) are well-established markers of fetal well-being and maturation of the fetal central nervous system. The purpose of this paper is to review and discuss the available knowledge on fetal movements and heart rate patterns in twin pregnancies. There is some evidence for an ...
Wydra Karolina - - 2013
We investigated the changes in dopamine (DA), glutamate and γ-aminobutyric acid (GABA) during cocaine self-administration in rats implanted with guide cannulae into the nucleus accumbens and ventral pallidum. After stabilized cocaine self-administration, separate groups of rats underwent extinction (10 days) procedure in which cocaine infusion was replaced by saline injections. ...
Choi Sung-Seen - - 2013
Co-matrix systems composed of a UV absorber and a UV stabilizer applied to the analysis of polystyrene (PS) using a matrix-assisted laser desorption/ionization-mass spectrometer (MALDI-MS) equipped with a N(2) laser (337 nm) as the light source were investigated. Various UV absorbers such as Tinuvin 234, Tinuvin 326, Tinuvin 327, Tinuvin ...
Gode David - - 2013
Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as the spatial analysis of peptides and proteins in biological tissue, the performance assessment of drugs in vivo or the measurement of protein or metabolite expression as tissue classifiers or biomarkers from disease versus control tissue comparisons. ...
Ou Zhiying - - 2013
ABSTRACT: BACKGROUND: Numerous diagnostic tests are available to detect Helicobactor pylori (H. pylori). There has been no single test available to detect H. pylori infection reliably. We evaluated the accuracy of a new fluorescence quantitative PCR (fqPCR) for H. pylori detection in children. METHODS: Gastric biopsy specimens from 138 children ...
Breivik Ingrid - - 2013
Abstract Adolescents with Asperger's syndrome (AS), often have handwriting difficulties that affect their academic performance. The purpose of this descriptive multiple-case mixed-method study was to highlight how adolescents with AS experience writing in the school setting when writing by hand and when using a computerized Assistive Technology Device (ATD), for ...
Reyes-Izquierdo Tania - - 2013
The present single-dose study was performed to assess the effect of whole coffee fruit concentrate powder (WCFC), green coffee caffeine powder (N677), grape seed extract powder (N31) and green coffee bean extract powder (N625) on blood levels of brain-derived neurotrophic factor (BDNF). Randomly assorted groups of fasted subjects consumed a ...
Wang Shi-Ming - - 2013
Polyoxometalate-TiO(2) composites have been successfully introduced into the photoanode of dye-sensitized solar cells to reduce the recombination of the electrons, which results in a longer electron lifetime. The performance of the cells with the polyoxometalate-modified photoanode is better than the cell with a pure P25 photoanode. The effect of the ...
Alcaide Benito - - 2013
The reactions of 3-allenyl 3-hydroxyoxindoles with a variety of halogenated reagents in the presence of catalytic amounts of precious metal salts were explored. Both, rearrangement and oxycyclization reactions to give 4-(1-halovinyl)-quinolinediones or spirocyclic halooxindoles, respectively, are competitive pathways. The kind of functionalization is substrate and reaction conditions dependent.
Almeida Riberet - - 2013
Manipulating and controlling water-based aqueous solutions with the use of 'virtual' walls is relatively simple as compared to non-aqueous low surface tension liquids which pose greater challenges in microfluidic devices. This paper reports a novel technique to form a virtual wall for various low surface tension liquids. A microfluidic channel ...
Bloch-Zupan Agnès - - 2013
ABSTRACT: BACKGROUND: Cockayne Syndrome CS (Type A -- CSA; or CS Type I OMIM #216400) (Type B -- CSB; or CS Type II OMIM #133540) is a rare autosomal recessive neurological disease caused by defects in DNA repair characterized by progressive cachectic dwarfism, progressive intellectual disability with cerebral leukodystrophy, microcephaly, ...
Dey Prabuddha - - 2013
AIM: To characterize a new isolate of Candida tropicalis for its enhanced storage lipid accumulation with respect to lipid composition, fatty acid profile and transcriptional regulation of four key genes involved in lipid productivity using different carbon sources. METHODS AND RESULTS: Upon growing C. tropicalis on various carbon substrates, glucose ...
Moosang Kim - - 2013
Purpose: To evaluate frequency and severity of segmentation errors of two spectral-domain optical coherence tomography (SD-OCT) devices and error effect on central macular thickness (CMT) measurements. Materials and Methods: Twenty-seven eyes of 25 patients with neovascular age-related macular degeneration, examined using the Cirrus HD-OCT and Spectralis HRA + OCT, were ...
Morris R G M RG Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, The University of Edinburgh, Edinburgh, UK. - - 2013
Three experiments were conducted to contrast the hypothesis that hippocampal N-methyl-d-aspartate (NMDA) receptors participate directly in the mechanisms of hippocampus-dependent learning with an alternative view that apparent impairments of learning induced by NMDA receptor antagonists arise because of drug-induced neuropathological and/or sensorimotor disturbances. In experiment 1, rats given a chronic ...
Mensink G B M GB Department of Epidemiology and Health Monitoring, Robert Koch Institute, General-Pape-Strasse 64, DE-12101 Berlin, - - 2013
Achieving an understanding of the extent of micronutrient adequacy across Europe is a major challenge. The main objective of the present study was to collect and evaluate the prevalence of low micronutrient intakes of different European countries by comparing recent nationally representative dietary survey data from Belgium, Denmark, France, Germany, ...
Weinborn Michael M School of Psychology, University of Western Australia, Crawley, Western Australia. - - 2013
Deficits in prospective memory (PM; i.e., enacting previously learned actions at the right occasion) and risky decision-making (i.e., making choices with a high chance of undesirable/dangerous outcomes) are both common among individuals with substance use disorders (SUD). Previous research has raised the possibility of a specific relationship between PM and ...
Paquette Julie - - 2013
AIMS: To determine the effect of a nurse telephone follow-up on paediatric post-tonsillectomy pain intensity, complications, and use of other healthcare services. BACKGROUND: After tonsillectomy, children experience moderate-to-severe pain for days. Parents tend to give insufficient analgesia, with resulting increases in pain and postoperative complications. In adults, nurse telephone follow-up ...
Shinoura Nobusada - - 2013
ABSTRACT The anatomic localization of brain functions can be characterized via diffusion tensor imaging (DTI) in patients with brain tumors and neurologic symptoms. The goal of the present study was to evaluate the function of the ventral, arcuate fasciculus (AF) and the superior longitudinal fasciculus (SLF)-related language pathways using these ...
Naderi Sahar - - 2013
Community-based interventions (CBI) have been targeted as a potential means of tackling cardiovascular disease in women. However, there have been mixed results in terms of their impact on health, with at least some of this being attributed to high attrition rates. This study explores factors that may be contributing to ...
Paerl Hans W - - 2013
Cyanobacteria are the Earth's oldest oxygenic photoautotrophs and have had major impacts on shaping its biosphere. Their long evolutionary history (∼3.5 by) has enabled them to adapt to geochemical and climatic changes, and more recently anthropogenic modifications of aquatic environments, including nutrient over-enrichment (eutrophication), water diversions, withdrawals, and salinization. Many ...
Acharya Deepak - - 2013
Hemolysis is a potential complication of mitral valve repair. We report a case of hemolytic anemia after mitral valve repair successfully treated with re-repair, and review the literature on reoperation after failure of mitral valve repair with associated hemolysis.
Luxán Guillermo - - 2013
Left ventricular noncompaction (LVNC) causes prominent ventricular trabeculations and reduces cardiac systolic function. The clinical presentation of LVNC ranges from asymptomatic to heart failure. We show that germline mutations in human MIB1 (mindbomb homolog 1), which encodes an E3 ubiquitin ligase that promotes endocytosis of the NOTCH ligands DELTA and ...
Stafford Kristen A - - 2013
INTRODUCTION: Cancer survivors are at increased risk for influenza-related complications. Racial disparities in preventive health services have not been extensively studied among cancer survivors. Our objective is to compare influenza vaccination prevalence among black and white cancer survivors METHODS: We performed a secondary data analysis of 41,346 white and black ...
Dileep Kalarickal Vijayan - - 2013
Phospholipase A2 (PLA(2)) is one of the key enzymes involved in the formation of inflammatory mediators. Inhibition of PLA(2) is considered to be one of the efficient methods to control inflammation. In silico docking studies of 160 selected indole derivatives performed against porcine pancreatic PLA(2) (ppsPLA(2)) suggested that, CID2324681, CID8617 ...
Yoneyama Takeshi - - 2013
Purpose For the application of less invasive robotic neurosurgery to the resection of deep-seated tumors, a prototype system of a force-detecting gripper with a flexible micromanipulator and force feedback to the operating unit will be developed. Methods Gripping force applied on the gripper is detected by strain gauges attached to ...
Long Mei-Rong - - 2013
A novel Gram-negative, aerobic, slightly halophilic, yellow-pigmented, oxidase-negative, Voges-Proskauer positive, non-spore-forming bacterium, designated YIM M 13059(T), was isolated from a sediment sample collected from the South China Sea at a depth of 310 m. Optimal growth was found to occur at 28-30 °C, pH 7.0 and in the presence of 3-4 % (w/v) ...
Tateishi Kazunari - - 2013
The clinical efficacy and outcomes of gefitinib therapy as a first-line treatment for elderly patients with non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations were analyzed retrospectively. We analyzed chemotherapy-naïve NSCLC patients aged 75 years or older who had EGFR mutations (exon 19 deletion mutation or L858R), who ...
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