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Fisher Anne G AG Division of Occupational Therapy, Department of Community Medicine and Rehabilitation, Umeå University, Umeå, Sweden. - - 2013
Since the beginning of the occupational therapy profession, engagement in occupation has been valued as the primary therapeutic agent as well as the goal of intervention. While there are few today who would not support this idea, occupational therapists continue to struggle with implementing their beliefs through "what we do" ...
Michel Stephan - - 2013
The central circadian pacemaker of the suprachiasmatic nuclei (SCN) is a bilaterally symmetrical structure. Little is known about the physiological mechanisms underlying communication between the left and right SCN and yet the degree of synchronization between SCN neurons can have a critical impact on the properties of the circadian system. ...
Schirwitz Christopher - - 2013
A method for the one-step purification of high-complexity peptide microarrays is presented. The entire peptide library is transferred from the synthesis support to a gold coated polyvinylidenfluoride (PVDF) membrane, whereby only full-length peptides covalently couple to the receptor membrane via an N-terminally added cysteine. Highly resolved peptide transfer and purification ...
Holzhauser Carolin - - 2013
The insertion of cyanine dye azides as energy donor dyes via postsynthetic "click"-type cycloaddition chemistry with e.g. a new thiazole orange azide combined with thiazole red yields dual emitting DNA probes with good fluorescence readout properties.
van Dijl Jan Maarten - - 2013
ABSTRACT: The biotechnology industry has become a key element in modern societies. Within this industry, the production of recombinant enzymes and biopharmaceutical proteins is of major importance. The global markets for such recombinant proteins are growing rapidly and, accordingly, there is a continuous need for new production platforms that can ...
Bhargava Arpit - - 2013
Aim: The work attempts to overcome tumor-associated immune tolerance using a surface-modified solid lipid nanoparticle (SLNP) delivery system for dendritic cell (DC) immunotherapy. Materials & methods: Different formulations of SLNPs (SLNPs-alone, cationic-SLNPs and mannosylated-SLNPs) were prepared using tumor cell lysates. Prepared nanoparticles were characterized and their ability to activate DCs ...
Purkait Suvendu - - 2013
Cell cycle regulator genes are major target of mutation in many human malignancies including glioblastomas (GBMs). CDKN2A is one such tumor suppressor gene which encodes p16INK4a protein and serves as an inhibitor of cell cycle progression. Very few studies are available regarding the association of CDKN2A deletion with p16 protein ...
Zhou Na - - 2013
A simple and sensitive electrochemical assay strategy of stripping voltammetry for mercury ions (Hg(2+)) detection is described based on the synergistic effect between ionic liquid functionalized graphene oxide (GO-IL) and gold nanoparticles (AuNPs). The AuNPs-GO-IL modified onto glassy carbon electrode (GCE) resulted in highly enhanced electron conductive nanostructured membrane and ...
Ferraço Renato - - 2013
Abstract Objectives: The aim of this study was to evaluate the stress distribution in mandibular free-end removable partial dentures (RPD) associated with FPD in the abutment teeth considering different inclinations of the residual ridge: (1) horizontal and (2) distal descending ridges and two designs of free-end RPD with different attachment ...
Ben Nasr Nesrine - - 2013
Structure Based Virtual Ligand Screening (SBVLS) methods are widely used in drug discovery programs. When several structures of the target are available, protocols based either on single structure docking or on ensemble docking can be used. The performance of the methods depends on the structure(s) used as a reference, whose ...
Shao Jie - - 2013
In order to explore the potential application of sulfur in aqueous rechargeable batteries, core-shell sulfur-polypyrrole (S@PPy) composites were prepared through a novel one-pot and surfactant-free method. Sulfur exhibits a very high capacity of 473 mA h g(-1) and good cycling stability in an aqueous Li(2)SO(4) electrolyte due to the polypyrrole ...
Lee Ju Min - - 2013
The incorporation of InP quantum-dot/N-doped multiwalled carbon nanotube (QD:NCNT) nanohybrids in the active layer of poly(3-hexylthiophene)/indene-C(60) bisadduct (P3HT/ICBA) bulk-heterojuction solar cells enhances V(OC) and J(SC) . The QDs encourage exciton dissociation by promoting electron transfer, while the NCNTs enhance the transport of the separated electrons and eventual charge collection. Such ...
Schroeder T - - 2013
The combination of azacitidine and donor lymphocyte infusions (DLI) as first salvage therapy for relapse after allogeneic transplantation (allo-HSCT) was studied in 30 patients with AML (n=28) or MDS (n=2) within a prospective single-arm multicenter phase-II trial. Treatment schedule contained up to 8 cycles azacitidine (100 mg/m(2)/d, d1-5, every 28d) ...
Labonté Marie-Ève - - 2013
The present randomised parallel study assessed the impact of adding MUFA to a dietary portfolio of cholesterol-lowering foods on the intravascular kinetics of apoAI- and apoB-containing lipoproteins in subjects with dyslipidaemia. A sample of sixteen men and postmenopausal women consumed a run-in stabilisation diet for 4 weeks. Subjects were then ...
Morris R G M RG Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, The University of Edinburgh, Edinburgh, UK. - - 2013
Three experiments were conducted to contrast the hypothesis that hippocampal N-methyl-d-aspartate (NMDA) receptors participate directly in the mechanisms of hippocampus-dependent learning with an alternative view that apparent impairments of learning induced by NMDA receptor antagonists arise because of drug-induced neuropathological and/or sensorimotor disturbances. In experiment 1, rats given a chronic ...
Dinić Svetlana - - 2013
The present study aimed to investigate the effects of the treatment with α-lipoic acid (LA), a naturally occurring compound possessing antioxidant activity, on liver oxidant stress in a rat model of streptozotocin (STZ)-induced diabetes by examining potential mechanistic points that influence changes in the expression of antioxidant enzymes such as ...
van der Zee Carlijn H - - 2013
Abstract Objective: The responsiveness of a new participation measure, the Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-Participation) was compared with that of the Impact on Particpation and Autonomy (IPA). Furthermore, the concurrent validity of these two measures was assessed. Method: Participants were patients with brain injury or neuromuscular disease, who ...
Filippatos Td - - 2013
Objectives: Patients with rheumatoid arthritis (RA) have increased cardiovascular risk. The aim of the present study was the assessment of low density lipoprotein (LDL) and high density lipoprotein (HDL) subclass distribution in patients with early RA (ERA, n = 30) compared with age- and sex-matched healthy subjects (n = 30), ...
Jacobs David R - - 2013
Food synergy is the concept that the non-random mixture of food constituents operates in concert for the life of the organism eaten and presumably for the life of the eater. Isolated nutrients have been extensively studied in well-designed, long-term, large randomised clinical trials, typically with null and sometimes with harmful ...
Cutler Andrew J - - 2013
Introduction/Objective Long-term use of the atypical antipsychotic iloperidone has not been investigated at doses above 16 mg/d. This article describes safety and tolerability results from the 25-week open-label extension of a 4-week placebo- and ziprasidone-controlled clinical trial of iloperidone. METHODS: Patients received a dose of 24 mg/d (given as 12 ...
Koehler Kenneth Christopher - - 2013
A synthetic amino acid bearing a furan functionality was developed and incorporated into peptide sequences using solid phase synthesis. Peptides expressing the furan moiety were attached to poly(ethylene glycol) (PEG) hydrogels through a thermally reversible covalent bond formed by a Diels-Alder reaction. Reactions of thiol and maleimide PEG macromers in ...
Wydra Karolina - - 2013
We investigated the changes in dopamine (DA), glutamate and γ-aminobutyric acid (GABA) during cocaine self-administration in rats implanted with guide cannulae into the nucleus accumbens and ventral pallidum. After stabilized cocaine self-administration, separate groups of rats underwent extinction (10 days) procedure in which cocaine infusion was replaced by saline injections. ...
Choi Sung-Seen - - 2013
Co-matrix systems composed of a UV absorber and a UV stabilizer applied to the analysis of polystyrene (PS) using a matrix-assisted laser desorption/ionization-mass spectrometer (MALDI-MS) equipped with a N(2) laser (337 nm) as the light source were investigated. Various UV absorbers such as Tinuvin 234, Tinuvin 326, Tinuvin 327, Tinuvin ...
Ivell Richard - - 2013
Maternal exposure to estrogenic xenobiotics or phthalates has been implicated in the distortion of early male reproductive development, referred to in humans as the testicular dysgenesis syndrome. It is not known, however, whether such early gestational and/or lactational exposure can influence the later adult-type Leydig cell phenotype. In this study, ...
Chen Hangjun - - 2013
ABSTRACT: BACKGROUND: The Chinese bayberry (Myrica rubra Sieb. and Zucc.) is a subtropical fruit native to China, with unique flavor, sweet and sour taste, and high nutrition and health values. The fruit is highly perishable and susceptible to mechanical injury, physiological deterioration and fungal decay once harvested. This study was ...
Hedelin Hans - - 2013
Abstract Objective. The aim of this study was to describe the prevalence of the chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) among middle-aged men in a region with a temperate climate, i.e. a community in western Sweden. Material and methods. Men aged 40-69 years who, on the basis of postal invitation, ...
Koochekpour Shahriar - - 2013
Asian Journal of Andrology advance online publication, 14 January 2013; doi:10.1038/aja.2012.145.
Moosang Kim - - 2013
Purpose: To evaluate frequency and severity of segmentation errors of two spectral-domain optical coherence tomography (SD-OCT) devices and error effect on central macular thickness (CMT) measurements. Materials and Methods: Twenty-seven eyes of 25 patients with neovascular age-related macular degeneration, examined using the Cirrus HD-OCT and Spectralis HRA + OCT, were ...
Suarez Hamlet - - 2013
Abstract Conclusions: The measurement of the energy consumption (EC) of the body's center of pressure (COP) to maintain the upright stance position was higher in elderly patients with bilateral vestibular hypofunction (BVH) compared with a control group and may be a valid parameter in the assessment of balance disorders. Objective: ...
Moran Patrick S - - 2013
Medline and Embase were searched for studies comparing robot-assisted radical prostatectomy with open prostatectomy and conventional laparoscopic prostatectomy. Random effects meta-analysis was used to calculate a pooled estimate of effect. The 95% prediction intervals are also reported. One randomized study and 50 observational studies were identified. The results show that ...
Dey Krishna Kanti - - 2013
A Pd nanoparticle-containing polymer microsphere moves with increasing speed across a pH gradient, following differential catalytic decomposition of aqueous hydrogen peroxide. The directional motion is akin to the pH taxis of living microorganisms. The artificial pH taxis exhibits random walk, translation, vertical, hopping, and pulsed motion, when the size of ...
Gamal-Eldin Mona A - - 2013
The formations of host-guest complexes between cucurbit[7]uril and a series of N-substituted N-methylpiperidinium, N-methylpyrrolidinium, and N-methylmorpholinium cations in aqueous solution have been investigated using (1)H NMR spectroscopy and electrospray ionization mass spectrometry. Dications comprising the N-methylheterocyclic head groups, bridged by a decamethylene chain, form sequential 1 : 1 ([2]pseudorotaxanes) and 2 : 1 host-guest ...
Laurenius Anna - - 2013
There is a lack of prevalent data for dumping syndrome (DS) and methods discriminating between different symptoms of the DS. A self-assessment questionnaire, the Dumping Symptom Rating Scale (DSRS), was developed. The aim was to measure the severity and frequency of nine dumping symptoms and to evaluate the construct validity ...
Pal Amit - - 2013
High prevalence of hypothyroxinaemia in iodine-deficient (ID) mothers has serious implications for mental health of the progeny. Independent supplementation of iodine and n-3 fatty acids (FA) markedly improves growth and cognitive performance of school children. Discerning effects of n-3 FA and iodine on the developing cerebellum have not been ascertained. ...
Heine Chyrisse - - 2013
AIM: The aims of the present study were to describe the trajectories of self-reported hearing difficulties over time, and evaluate the impacts of age, sex, lifestyle factors and social activity, in explaining individual differences in patterns of change over time. METHODS: As part of the Melbourne Longitudinal Studies on Healthy ...
Breivik Ingrid - - 2013
Abstract Adolescents with Asperger's syndrome (AS), often have handwriting difficulties that affect their academic performance. The purpose of this descriptive multiple-case mixed-method study was to highlight how adolescents with AS experience writing in the school setting when writing by hand and when using a computerized Assistive Technology Device (ATD), for ...
Ehret David - - 2013
A two-year study of antioxidants in greenhouse tomato was conducted. Plants were treated continuously with nutrient solution electrical conductivities (EC) of 2, 4, or 6 dS m-1. Increasing EC reduced yield per plant and fruit size. Oxygen radical absorbance capacity (ORAC), lutein, β-carotene, lycopene and vitamin C concentrations were evaluated ...
Scarlata Simone - - 2013
AIM: Restrictive lung dysfunction (RLD; defined as reduced forced vital capacity [FVC] in the presence of normal forced expiratory volume in 1 s [FEV1]/FVC ratio) is highly prevalent in the elderly, and is associated with diabetes, metabolic syndrome (MetS) and abdominal obesity. The aim of this study was to assess the ...
Smith Joanna - - 2013
BACKGROUND: Living with a child with a long-term condition can result in challenges above usual parenting because of illness-specific demands. A critical evaluation of research exploring parents' experiences of living with a child with a long-term condition is timely because international health policy advocates that patients with long-term conditions become ...
Gupta Girish K - - 2013
Aim: A layer-by-layer matrix (LBL) comprising kaempferol (LBL-KEM) was prepared for improved osteogenic action. Materials & methods: The LBL-KEM consisted of alternate layers of sodium alginate and protamine sulfate, which were sequentially deposited on the preformed kaempferol (KEM)-loaded CaCO(3) core (CaCO(3)-KEM) by LBL self-assembly. The LBL matrix developed was evaluated ...
Shmulewitz D D New York State Psychiatric Institute, New York, NY, - - 2013
The fifth edition of the diagnostic and statistical manual of mental disorders (DSM-5) proposes aligning nicotine use disorder (NUD) criteria with those for other substances, by including the current DSM fourth edition (DSM-IV) nicotine dependence (ND) criteria, three abuse criteria (neglect roles, hazardous use, interpersonal problems) and craving. Although NUD ...
Pelicand Julie - - 2013
BACKGROUND: This study examines how the term 'self-care' imported from health promotion has been used in the context of patient education interventions for paediatric patients with type 1 diabetes. METHODS: Thirty articles over the last decade were analysed, using a qualitative method of thematic coding and categorizing. RESULTS: The term ...
Langley-Evans Simon C - - 2013
The developmental origins of health and disease hypothesis postulates that exposure to a less than optimal maternal environment during fetal development programmes physiological function, and determines risk of disease in adult life. Much evidence of such programming comes from retrospective epidemiological cohorts, which demonstrate associations between birth anthropometry and non-communicable ...
Hirschmann Thomas Ch - - 2013
The optical characterization of bundled and individual triple-walled carbon nanotubes was studied for the first time in detail by using resonant Raman spectroscopy. In our approach, the outer tube of a triple-walled carbon nanotube system protects the two inner tubes (or equivalently the inner double-walled carbon nanotube) from external environment ...
Deane Fiona M - - 2013
Drugs that inhibit DNA topoisomerase I and DNA topoisomerase II have been widely used in cancer chemotherapy. We report herein the results of a focused medicinal chemistry effort around novel ellipticinium salts which target topoisomerase I and II enzymes with improved solubility. The salts were prepared by reaction of ellipticine ...
Szulc Michal - - 2013
There is a hypothesis that ghrelin could take part in the central effects of alcohol as well as function as a peripheral indicator of the changes which occur during long-term alcohol consumption. The aim of this study was to determine a correlation between alcohol concentration and acylated and total form ...
Almeida Riberet - - 2013
Manipulating and controlling water-based aqueous solutions with the use of 'virtual' walls is relatively simple as compared to non-aqueous low surface tension liquids which pose greater challenges in microfluidic devices. This paper reports a novel technique to form a virtual wall for various low surface tension liquids. A microfluidic channel ...
Dey Prabuddha - - 2013
AIM: To characterize a new isolate of Candida tropicalis for its enhanced storage lipid accumulation with respect to lipid composition, fatty acid profile and transcriptional regulation of four key genes involved in lipid productivity using different carbon sources. METHODS AND RESULTS: Upon growing C. tropicalis on various carbon substrates, glucose ...
Dimitroulas T - - 2013
Objective: To determine whether demographic, inflammatory, and metabolic factors predict elevated asymmetric dimethylarginine (ADMA) levels in rheumatoid arthritis (RA). Method: A total of 67 RA patients [mean age 56 ± 12 years, median disease duration 8 (3-15) years] were assessed. Routine biochemistry tests, lipid profile, glycaemic profile [glucose, insulin, homeostasis ...
Herbst Florian - - 2013
As polymers and polymeric materials are "the" smart invention and technological driving force of the 20th century, the quest for self-healing or self-repairing polymers is strong. The concept of supramolecular self-healing materials relies on the use of noncovalent, transient bonds to generate networks, which are able to heal the damaged ...
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