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Criaco D - - 2013
In a previous paper a mathematical model was developed for the dynamics of activation and clonal expansion of T cells during the immune response to a single type of antigen challenge, constructed phenomenologically in the macroscopic framework of a thermodynamic theory of continuum mechanics for reacting and proliferating fluid mixtures. ...
Vyncke Krishna E - - 2013
The present study assessed whether compliance with the Food-Based Dietary Guidelines is related to habitual fatty acid (FA) intake and blood lipid parameters. Dietary information was collected by two non-consecutive 24-h recalls in 1804 European adolescents. Compliance with the Food-Based Dietary Guidelines was expressed by calculating the Diet Quality Index ...
Yi Chucai - - 2013
In this paper, we propose a novel algorithm to detect text information from natural scene images. Scene text classification and detection are still open research topics. Our proposed algorithm is able to model both character appearance and structure to generate representative and discriminative text descriptors. The contributions of this paper ...
Pun Stephanie Y - - 2013
The most favorable mechanical environment for the hip is one that is free of both instability and impingement, creating a concentric articulation with optimum femoral head coverage by the acetabulum. Anatomic variations such as acetabular dysplasia with associated instability, and femoroacetabular impingement with abnormal constraint, will lead to abnormal joint ...
Taub Pam R - - 2013
Epidemiological data demonstrates that improved regulation of blood glucose correlates with better cardiovascular (CV) outcomes. Conversely, some interventional studies have demonstrated that tight glycemic control has no benefit or can even result in worse CV outcomes. These conclusions parallel the paradox that glycemic control has proven beneficial for microvascular outcomes, ...
De Ambrosi Cristina - - 2013
We started offering an introduction to very basic aspects of molecular biology, for the reader coming from computer sciences, information technology, mathematics. Similarly we offered a minimum of information about pathways and networks in graph theory, for a reader coming from the bio-medical sector. At the crossover about the two ...
Barichella Michela - - 2013
Dietary treatment is important for the management of Parkinson's disease (PD). Our objective was to describe the dietary habits and assess the nutritional status of Ghanaian patients with PD. This study is part of a larger project, for which Ghana has been selected as a pilot country. Fifty-five Ghanaian patients ...
Tello J Ignacio - - 2013
We consider a simple mathematical model of tumor growth based on cancer stem cells. The model consists of four hyperbolic equations of first order to describe the evolution of different subpopulations of cells: cancer stem cells, progenitor cells, differentiated cells and dead cells. A fifth equation is introduced to model ...
Abhishek A - - 2013
Osteoarthritis (OA), the commonest arthropathy, targets the knees, hips, finger interphalangeal joints, thumb bases, first metatarsophalangeal joints, and spinal facet joints, and displays marked heterogeneity of clinical presentation. Signs of OA include coarse crepitus, bony enlargement, reduced range of movement, and joint-line tenderness. Muscle wasting and joint deformity occur with ...
VanderBeek Brian L BL Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA. - - 2013
To determine if statins are associated with the development or progression of age-related macular degeneration (AMD). A large, national insurance claims database was reviewed to identify individuals aged 60 years or older who were enrolled for ≥2 years and had ≥1 visits to an eye provider. Prescription claims for statins ...
Löwenberg Mark - - 2013
In recent years, many new agents have been evaluated for the treatment of inflammatory bowel disease. In this paper, we critically review recently published literature about these novel therapies, which have been the result of extensive research identifying molecular targets. Of the various biologicals and small molecules that have recently ...
Properzi Enrico - - 2013
In this article we show how dichotomic classes, binary variables naturally derived from a new mathematical model of the genetic code, can be used in order to characterize different parts of the genome. In particular, we analyze and compare different parts of whole chromosome 1 of Arabidopsis thaliana: genes, exons, ...
Goldstein Lou Ann - - 2013
ABSTRACT Family involvement is essential to the developmental outcome of infants born into Neonatal Intensive Care Unit (NICU). In this article, evidence has been presented on the parent's perspective of having an infant in the NICU and the context of family. Key points to an educational assessment are also reviewed. ...
Ramakrishna Harish - - 2013
Cardiothoracic and vascular critical care has emerged as a subspecialty due to procedural breakthroughs, an aging population, and a multidisciplinary collaboration. This subspecialty now has a dedicated professional society, recently published guidelines, and plans for standardized certification. This paradigm shift represents a major collaboration opportunity for our specialty. The rise ...
MacDonald D D Division of Oral and Maxillofacial Radiology, Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, - - 2013
The solitary keratocystic odontogenic tumor (KCOT) is a neoplasm, which recurs in 28% of cases. The purpose of this study is to determine whether clinicoradiographic features can predict recurrence. From 2000 to 2009, 106 solitary KCOTs were retrieved from the Oral Biology Service of British Columbia. Among 58 KCOTs including ...
Clarke Collin F M - - 2013
Functional imaging of the central nervous system has been utilized since the 1970s focusing on the concept that neural functioning is coupled to regional cerebral blood flow. This has allowed for extensive mapping of the neural pathways associated with pain, the "pain-matrix." The study of the functional anatomy utilizes positron ...
Macintyre Linda M - - 2013
Malawi women are in the ironic juxtaposition of being socially disempowered while, at the same time, thought to hold the key to shaping an effective community response to the HIV crisis. Based on this juxtaposition, a descriptive, qualitative study was conducted in Malawi and the United States where 26 participants ...
Neff Guy W GW Tampa General Medical Group, Tampa, FL 33606, USA. - - 2013
The purpose of this study was to assess the incidence of Clostridium difficile infection in patients who received rifaximin for the treatment of hepatic encephalopathy (HE). Medical charts of patients who received rifaximin for the treatment of HE were reviewed. The number of patients who developed diarrhea during treatment with ...
Wang Lin - - 2013
Puerarin (PU), a natural flavonoid, has been reported to possess anti-oxidative and anti-inflammatory activities. In the present study, female Sprague-Dawley rats received lead (Pb) nitrate (300 mg/L, via drinking water) and/or PU (400 mg/kg/day, orally) to investigate the protective effects of PU on Pb-induced renal damage. Renal toxicity was evaluated by detecting ...
Azadbakht Leila - - 2013
To assess the association between consuming or skipping breakfast and dietary quality indices such as the Healthy Eating Index (HEI), the Dietary Diversity Score (DDS), diversity scores of different food groups, and anthropometric measurements in young Isfahanian women. Women 18 to 28 y old were selected randomly from among university ...
Suk Jung Im JI Department of Neurology, School of Medicine, Catholic University of Daegu, 3056-6, Daemyeong-4-dong, Nam-gu, Daegu, South Korea. - - 2013
Over the last decade, neuromuscular ultrasonography has emerged as a useful tool for the diagnosis of peripheral nerve disorders. This article reviews sonographic findings of normal nerves, including key quantitative ultrasound measurements that are helpful in the evaluation of focal and possibly generalized peripheral neuropathies. It also discusses several recent ...
Chen Susie A - - 2013
Locoregional control is associated with breast cancer-specific and overall survival in select women with breast cancer. Although several patient, tumor, and treatment characteristics have been shown to contribute to locoregional recurrence (LRR), studies evaluating factors related to radiotherapy (XRT) technique have been limited. We investigated the relationship between LRR location ...
Candido Kenneth D - - 2013
Cervical epidural steroid injections (CESI) are an accepted treatment for neck pain with a radicular component, and may be accomplished by using either transforaminal (CTFESI) or interlaminar (CILESI) approaches. CESIs are routinely performed using real-time fluoroscopic-guidance in conjunction with the injection of water soluble, iodine-based contrast media to enhance visualization ...
Gondi Vinai - - 2013
To prospectively evaluate the association between hippocampal dose and long-term neurocognitive function (NCF) impairment for benign or low-grade adult brain tumors treated with fractionated stereotactic radiotherapy (FSRT). Adult patients with benign or low-grade adult brain tumors were treated with FSRT per institutional practice. No attempt was made to spare the ...
Kluger Nicolas - - 2013
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) (or autoimmune polyendocrine syndrome type 1) is a rare autosomal recessive disorder caused by mutations in the autoimmune regulator gene. It causes a loss in central immune tolerance, failure to eliminate autoreactive T cells in the thymus, and their escape to the periphery. APECED patients are ...
Pawlotsky Jean-Michel - - 2013
Hepatitis C virus (HCV) RNA level monitoring is currently used to guide the duration of interferon-containing treatment regimens. Nowadays, HCV RNA level quantification is based on real-time polymerase chain reaction assays that are both sensitive and accurate. Assessing the virological response to therapy is used to shorten treatment duration in ...
Bunn Belinda K - - 2013
Kaposi sarcoma is the most common HIV-associated neoplasm, frequently presenting with oral mucosal involvement. This retrospective study aimed to assess and highlight the histomorphological spectrum of oral Kaposi sarcoma. A total of 135 cases diagnosed between 1990 and 2011 were retrieved from the archives of the Oral and Dental Hospital ...
Schambach Axel A Institute of Experimental Hematology, Hannover Medical School, D-30625 Hannover, - - 2013
Over the past decades, lentiviral vectors have evolved as a benchmark tool for stable gene transfer into cells with a high replicative potential. Their relatively flexible genome and ability to transduce many forms of nondividing cells, combined with the potential for cell-specific pseudotyping, provides a rich resource for numerous applications ...
Carinci Adam J - - 2013
Chronic pelvic pain (CPP) is a significant clinical entity that affects both men and women alike. The etiologies of CPP are multifactorial, and treatments are myriad. Complementary and Alternative Medicine (CAM) refers to non-allopathic health systems, and its use is popular in the United States. In particular, several recent studies ...
d'Onofrio Alberto - - 2013
There is an increasing awareness that to properly understand how tumors originate and grow, and then how to develop effective cures, it must be taken into account the dynamics of tumors and its great complexity. Tumors are characterized not only by the coexistence of multiple scales, both temporal and spatial, ...
Guermazi Ali - - 2013
Osteoarthritis (OA) is the most prevalent joint disorder in the elderly, and there is no effective treatment. Imaging is essential for evaluating the synovial joint structures (including cartilage, meniscus, subchondral bone marrow and synovium) for diagnosis, prognosis, and follow-up. This article describes the roles and limitations of both conventional radiography ...
Smecuol Edgardo - - 2013
: The aim of this exploratory trial was to establish if the probiotic Bifidobacterium natren life start (NLS) strain strain may affect the clinical course and pathophysiological features of patients with untreated celiac disease (CD). Positive findings would be helpful in directing future studies. : Twenty-two adult patients having 2 ...
Armstead William M WM Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, USA. - - 2013
Traumatic brain injury contributes to morbidity in children and boys are disproportionately represented. Autoregulation is impaired more in male compared with female piglets after traumatic brain injury through sex-dependent up-regulation of the spasmogen endothelin-1 and extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK), a family of three kinases: ERK, p38, ...
Di Cello Francescopaolo F Hematology Division, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, - - 2013
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive leukemia with high relapse rates compared to B-lineage ALL. We previously showed that HMGA1a transgenic mice develop aggressive T-ALL, indicating that HMGA1 causes leukemic transformation in vivo. HMGA1 is also highly expressed in embryonic stem cells, hematopoietic stem cells and diverse, refractory ...
Vurucu S - - 2013
The aim of this study was to investigate the relationship between oxidative stress and chronic daily headache (CDH) in children. Although there are reports that oxidative injury may play a role in the pathophysiology of some neurologic disorders, such as migraine and epilepsy, by disrupting or destroying cell membranes through ...
Bueno Milena Baptista - - 2013
To estimate the nutritional risk in children 2 to 6 y old. The sample consisted of 3058 children enrolled in public and private schools in nine Brazilian cities. The assessment of nutrient intake was based on 1-d data combining direct individual weighing of foods and a food diary. A second ...
Wiles Charles Mark - - 2013
Neurological examination (NE) is a key part of practice for many doctors. UK students learn NE from a variety of specialty tutors and often find it difficult. This article suggests one way of introducing NE interactively with students in their first clinical year supplementary to clerking patients. The content presupposes ...
Caravagna Giulio - - 2013
A tumor is kinetically characterized by the presence of multiple spatio-temporal scales in which its cells interplay with, for instance, endothelial cells or Immune system effectors, exchanging various chemical signals. By its nature, tumor growth is an ideal object of hybrid modeling where discrete stochastic processes model low-numbers entities, and ...
Kuppinger David - - 2013
The Nutritional Risk Screening-2002 (NRS-2000) is currently recommended by the European Society of Parenteral and Enteral Nutrition as a screening tool in hospitalized patients. However, for preoperative risk prediction, the usefulness of this tool is uncertain and may depend on the type of surgical disease. The present study investigated the ...
Matthews Gloria L - - 2013
Osteoarthritis (OA) is a significant and growing concern to a large segment of the population. Effective treatments for slowing or stopping the progression of the disease are not available despite a great deal of investment-backed effort on the part of academia, government, and the pharmaceutical industry. Target selection has been ...
Siegwart John T JT Jr Department of Vision Sciences, School of Optometry, University of Alabama at Birmingham, Birmingham, Alabama 35294-4390, USA. - - 2013
To determine if early restraint of axial elongation in response to plus lenses increases the subsequent response to interrupted hyperopia in tree shrews. The normal interrupted hyperopia group (n = 5) had normal visual exposure until 24 days of visual experience (VE). Then, from 24 to 45 days of VE, ...
D'Antonio Gianluca - - 2013
The basement membrane (BM) and extracellular matrix (ECM) play critical roles in developmental and cancer biology, and are of great interest in biomathematics. We introduce a model of mechanical cell-BM-ECM interactions that extends current (visco)elastic models (e.g. [8,16]), and connects to recent agent-based cell models (e.g. [2,3,20,26]). We model the ...
Lugonja Nikoleta - - 2013
Early-onset and exclusive breast-feeding provides a significant health benefit to infants compared with infant formulas. The aim of this study was to compare mature breast milk with standard infant formulas by examining their effects on non-vascular smooth muscle contraction and their antioxidative properties. The pharmacologic effects of breast milk and ...
Bagdasarov Zhanna - - 2013
We investigated the role of anger expression and cultural framework in predicting Russian immigrant women's physical and psychological health status. One hundred Russian immigrant women between the ages of 30 and 65 completed questionnaires assessing anger expression, cultural framework, and health status. All research questions were addressed using hierarchical regression ...
Scianna Marco - - 2013
Cell migration on and through extracellular matrix is fundamental in a wide variety of physiological and pathological phenomena, and is exploited in scaffold-based tissue engineering. Migration is regulated by a number of extracellular matrix- or cell-derived biophysical parameters, such as matrix fiber orientation, pore size, and elasticity, or cell deformation, ...
Wilson David R - - 2013
Mechanics play a role in the initiation and progression of osteoarthritis. However, our understanding of which mechanical parameters are most important, and what their impact is on the disease, is limited by the challenge of measuring the most important mechanical quantities in living subjects. Consequently, comprehensive statements cannot be made ...
Rodrigues Diego Samuel - - 2013
Dosage and frequency of treatment schedules are important for successful chemotherapy. However, in this work we argue that cell-kill response and tumoral growth should not be seen as separate and therefore are essential in a mathematical cancer model. This paper presents a mathematical model for sequencing of cancer chemotherapy and ...
Galhardo Alessandra Pucci Mantelli - - 2013
The aim of this study was to evaluate the performance of research diagnostic criteria for temporomandibular disorders (RDC/TMD) as a diagnostic test for temporomandibular joint problems using magnetic resonance imaging (MRI) as the gold standard. Sixty-seven women were assessed with RDC/TMD (2 examiners) and underwent MRI examination (3.0 T). Images ...
Asrani Sumeet K - - 2013
Significant strides have been made in the last few years in advancing our knowledge of the natural history of cirrhosis. These include (1) a better understanding of prognosis in compensated and decompensated cirrhosis, (2) improved estimates of the natural course of variceal bleeding in patients receiving standard of care therapy, ...
Chanpong Brian - - 2013
The purpose of this study was to develop a methodological technique for the ultrasonographic visualization of the inferior alveolar nerve (IAN) using a novel hockey stick-shaped 8- to 15-MHz transducer in volunteers, followed by simulated IAN scanning and injection in cadavers. In 20 volunteers, bilateral scans of the IAN nerve ...
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