Search Results
Results 651 - 700 of 4440
< 9 10 11 12 13 14 15 16 17 18 19 >
Ayari H - - 2013
ABSTRACT Purpose: Vascular calcification was considered to be a passive, degenerative, and end-stage process of vascular disease. However, bone associated proteins such as bone morphogenetic proteins, osteopontin, osteonectin, osteocalcin, and matrix Gla protein (MGP) have been found in the calcified atherosclerotic lesions. We studied by microarray analysis whether intact tissue ...
Mao Limin - - 2013
HIV-related risk perceptions and risk practices among gay men have changed over time. We revisited perceived HIV risk and engagement in anal intercourse with casual partners among HIV-negative gay men who participated in one of the Sydney Gay Community Periodic Surveys (GCPS). Perceived HIV risk was assessed by a range ...
Coulibaly G - - 2013
In subjects infected with HIV, proteinuria could represent a marker of HIV associated nephropathy (HIVAN), the most important cause of chronic renal failure in them. To determine the prevalence of proteinuria in children with HIV infection and to improve the screening of renal disease for these children in our country, ...
Yang Jun - - 2013
Hirschsprung's disease (HSCR) is a complex developmental defect characterized by the absence of enteric ganglia in the gastrointestinal tract. Although the genetic defect of enteric nervous system (ENS) was identified to play a critical role in the progress of HSCR, the systemic genetic dissection of HSCR still needs to be ...
Ludwig Antje A Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie, Charité, Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany. - - 2013
Magnetic resonance imaging (MRI) with contrast agents that target specific inflammatory components of atherosclerotic lesions has the potential to emerge as promising diagnostic modality for detecting unstable plaques. Since a high content of macrophages and alterations of the extracellular matrix are hallmarks of plaque instability, these structures represent attractive targets ...
Buyukasik Y - - 2013
Clinical data suggest that platelet functional capacity and consequently bleeding risk are heterogeneous in various causes of thrombocytopenia [1-4]. Bleeding manifestations are relatively rare in patients with idiopathic thrombocytopenic purpura (ITP) as compared with equally thrombocytopenic patients with megakaryocyte deficiency. Hemorrhage may occur at apparently acceptable platelet levels in various ...
Zhang Jingjing - - 2013
The vesicle is found to form in the concentrated aqueous solution of ionic liquid 1-dodecyl-3-methylimidazolium bromide (C12mimBr) and β-CD. By decreasing temperature, the vesicle changes into a novel supramolecular hydrogel constructed from lamellae. The process is reversible and reproducible. The mechanism for the formation of vesicles and supramolecular hydrogel is ...
Louis-Sylvestre Christine - - 2013
INTRODUCTION AND HYPOTHESIS: Abdominal sacrocolpopexy is the gold standard treatment for pelvic organ prolapse and can be performed laparoscopically. Robotic assistance allows optimal dissection and placement of the prosthesis. We present a video of our technique along with the results on 90 patients. METHODS: We perform a posterior dissection down ...
Ruhland Thomas M - - 2013
We investigate the self-assembly behavior of Janus particles with different geometries at a liquid - liquid interface. The Janus particles we focus on are characterized by a phase-separation along their major axis into two hemicylinders of different wettability. We present a combination of experimental and simulation data together with detailed ...
Costal Flavia - - 2013
BACKGROUND: Loss of β-cell function hastens deterioration of metabolic control in type 2 diabetes patients. Besides amyloid deposit and lipo- and glucotoxicity, AGEs seem to contribute to this process by promoting islet apoptosis. In order to investigate the role of AGEs in β-cell deterioration, we evaluated the temporal and dose ...
Ge Xianxiu - - 2013
BACKGROUND AND OBJECTIVE: NK4, a competitive antagonist for hepatocyte growth factor (HGF) and the Met receptor, is a bifunctional molecule that acts as an HGF antagonist and an angiogenesis inhibitor. The objective of this study was to investigate the anti-tumor effects of NK4 on the cholangiocarcinoma (CCA) cell line HuCC-T1. ...
Sciascia Savino - - 2013
Objective. To develop and validate a risk score [global APS score (GAPSS)] derived from the combination of independent risk for thrombosis and pregnancy loss (PL), taking into account the aPL profile, conventional cardiovascular risk factors and the autoimmune antibody profile.Methods. This cross-sectional study included 211 consecutive SLE patients. Data on ...
Eckardt J - - 2013
Osteogenesis imperfecta (OI) is a genetic disorder causing defects in the development of collagen type I. Clinical signs of affected dachshunds include multiple fractures of bones, joint hyperlaxity and dentinogenesis imperfecta. Recently, a recessive mutation in the SERPINH1 gene was detected in dachshunds and enabled the development of a DNA ...
Delgado Almandoz Josser E - - 2013
BACKGROUND: There is wide variability in the reported incidence of perioperative thromboembolic (0-14%) and hemorrhagic (0-11%) complications after Pipeline Embolization Device (PED) procedures for cerebral aneurysm treatment, which could be partly due to differences in patient response to the P2Y12 receptor antagonist administered while the PED endothelializes. This study aims ...
Ramirez-Moreno David F - - 2013
This work proposes a model of visual bottom-up attention for dynamic scene analysis. Our work adds motion saliency calculations to a neural network model with realistic temporal dynamics [(e.g., building motion salience on top of De Brecht and Saiki Neural Networks 19:1467-1474, (2006)]. The resulting network elicits strong transient responses ...
Avendano Carlos - - 2013
In the first paper of this series [C. Avendaño et al. J. Phys. Chem. B 2011, 115, 11154] we introduced the SAFT-g force field for molecular simulation of fluids. In our approach a molecular-based equation of state (EoS) is used to obtain coarse-grained (CG) intermolecular potentials that can be used ...
Mungrue Kameel - - 2013
Abstract Background: The aim of this study is to measure the occurrences of the following risk factors: tobacco use, levels of physical activity, levels of physical inactivity, and body mass index (BMI) among adolescents in Trinidad. Methods: A two-stage random sampling process was used to select schools and students. Data ...
Mu Lina L Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, SUNY, 270 Farber Hall, Buffalo, NY 14214, USA. - - 2013
To investigate indoor particulate matter (PM) level and various indoor air pollution exposure, and to examine their relationships with risk of lung cancer in an urban Chinese population, with a focus on non-smoking women. We conducted a case-control study in Taiyuan, China, consisting of 399 lung cancer cases and 466 ...
Dhanasekaran M - - 2013
Current protocols of islet cell transplantation for the treatment of diabetes mellitus have been hampered by islet availability and allograft rejection. Although bone marrow and subcutaneous adipose tissue stem cells feature their tissue repair efficacy, applicability of stem cells from various sources is being researched to develop a promising therapy ...
Taher Leena Yaseen - - 2013
Aggressive fibromatosis is a benign but locally-aggressive tumor, which most often affects the muscles of the shoulder, the pelvic girdle, and the thigh. It usually affects adolescents and young adults. Desmoplastic fibroma, considered the bone counterpart of soft tissue fibromatosis, is a rare tumor that usually affects the metaphyseal or ...
Oriá Arianne P - - 2013
BACKGROUND: The accumulation of pus in the orbit originating from an infected dental root is classified as odontogenic intraorbital abscess. METHODS: Clinical, laboratory, and image evaluation of a non-human primate was performed. RESULTS: The patient was cured after surgical therapy. CONCLUSIONS: This represents the first report of an odontogenic periodontal ...
Boonyagul Sani - - 2013
Aloe vera is a traditional wound healing medicine. We hypothesized acemannan, a polysaccharide extracted from Aloe vera gel, could affect bone formation. Primary rat bone marrow stromal cells (BMSCs) were treated with various concentrations of acemannan. New DNA synthesis, VEGF, BMP-2, alkaline phosphatase activity, bone sialoprotein, osteopontin expression, and mineralization ...
Rivero Maria R MR Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, Friuli 2434, 5000, Córdoba, - - 2013
The early branching Giardia lamblia has highly polarized vacuoles, located underneath the plasma membrane, which have at least some of the characteristics of endosomes and of lysosomes. These peripheral vacuoles (PVs) are necessary for nutrient uptake and the maintenance of plasma membrane composition, but whether they carry out sorting and ...
Arnson Yoav - - 2013
Myocardial infarction (MI) is the most common cause of cardiac injury in the Western world. Cardiac injury activates innate immune mechanisms initiating an inflammatory reaction. Inflammatory cytokines and vascular cell adhesion molecules (VCAM) promote adhesive interactions between leukocytes and endothelial cells, resulting in the transmigration of inflammatory cells into the ...
Yeh Kuo-Wei - - 2013
This population-based study aimed to determine the trend of incidence, prevalence, and mortality of systemic lupus erythematosus (SLE) in a 6-year period in Taiwan. Patients with international classification of diseases ninth revision (ICD-9) code 710.0 were retrieved from the Taiwanese National Health Insurance Research Database (NHIRD), which covered more than ...
Zhao Hang - - 2013
Behçet's disease (BD) is a multi-system inflammatory disorder. We report the case of a BD patient with severe aortic root vasculitis. Two-dimensional transthoracic echocardiography (2DE) images suggested left Valsalva sinus aneurysm ruptured into the left ventricular outflow tract. However, preoperative transesophageal real-time 3-dimensional echocardiography (3DE) revealed that the aneurysm-like structure ...
Karthikeyan Marimuthu - - 2013
Abstract Background: The aim of the study was to evaluate the incidence of medication error and to categorize medication error in the general medicine department of a tertiary hospital. Thus, the study aims to promote safety in medication use and ensure quality in the healthcare service by effective utilization of ...
Kotsis Fruzsina - - 2013
Since the discovery that proteins mutated in different forms of polycystic kidney disease (PKD) are tightly associated with primary cilia, strong efforts have been made to define the role of this organelle in the pathogenesis of cyst formation. Cilia are filiform microtubular structures, anchored in the basal body and extending ...
Hansen Michael Riis - - 2013
The type I phosphoribosyltransferase OMP synthase (EC 2.4.2.10) is involved in de novo synthesis of pyrimidine nucleotides forming the UMP precursor orotidine 5'-monophosphate (OMP). The homodimeric enzyme has a Rossman α/β core topped by a base-enclosing "hood" domain and a flexible domain-swapped catalytic loop. High-resolution X-ray structures of the homologous ...
Hallen André - - 2013
A key intermediate in the glutamate dehydrogenase (GDH)-catalyzed reaction is an imine. Mechanistically, therefore, GDH exhibits similarities to the ketimine reductases. In the current review, we briefly discuss (a) the metabolic importance of the GDH reaction in liver and brain, (b) the mechanistic similarities between GDH and the ketimine reductases, ...
Chetram Mahandranauth A MA Center for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314, - - 2013
Reactive oxygen species (ROS) play a central role in oxidative stress, which leads to the onset of diseases, such as cancer. Furthermore, ROS contributes to the delicate balance between tumor cell survival and death. However, the mechanisms by which tumor cells decide to elicit survival or death signals during oxidative ...
Hashimoto Shu S IVF Namba Clinic, Osaka, Japan. - - 2013
Closed-system vitrification may enable the risk of contamination to be minimised. We performed three studies to compare the developmental competence of human embryos vitrified using either a closed vitrification system (CVS; Rapid-i®) or an open vitrification system (OVS; Cryo-top®). The first study was performed in vitro using 66 zygotes previously ...
Albamonte María Itatí MI Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico, Universidad Maimónides, Buenos Aires, - - 2013
How do apoptosis-related BCL2 and BAX genes, known to regulate death or survival of germ cells in fetal and adult life, and germ-cell-specific VASA protein behave from birth to puberty in the human ovary? In resting primordial follicles in both infant and pubertal ovaries, BCL2 family members and germ-cell-specific VASA ...
Crosslin David R DR Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA, USA. - - 2013
With white blood cell count emerging as an important risk factor for chronic inflammatory diseases, genetic associations of differential leukocyte types, specifically monocyte count, are providing novel candidate genes and pathways to further investigate. Circulating monocytes play a critical role in vascular diseases such as in the formation of atherosclerotic ...
Chamberlain Catherine - - 2013
BACKGROUND: Recently proposed international guidelines for screening for Gestational Diabetes Mellitus (GDM) recommend additional screening in early pregnancy for sub-populations at a high risk of Type 2 Diabetes Mellitus (T2DM), such as indigenous women. However, there are criteria that should be met to ensure the benefits outweigh the risks of ...
Luo P P Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, 2200 Pierce Avenue, 560 RRB, Nashville, TN 37232-6602, - - 2013
Obesity is associated with aldosterone excess, hypertension and the metabolic syndrome, but the relative contribution of aldosterone to obesity-related complications is debated. We previously demonstrated that aldosterone impairs insulin secretion, and that genetic aldosterone deficiency increases glucose-stimulated insulin secretion in vivo. We hypothesised that elimination of endogenous aldosterone would prevent ...
Yegorenkova Irina V - - 2013
We examined the ability of several Paenibacillus polymyxa strains to colonize wheat roots and the ability of P. polymyxa exoglycans to induce root hair deformation. For the first time, exopolysaccharides isolated from P. polymyxa were found to produce, with different intensities, various morphological changes in the root hairs of wheat ...
Haider Saida - - 2013
Lead toxicity is known to induce a broad range of physiological, biochemical and behavioral dysfunctions that may result in adverse effects on several organs, including the central nervous system. Long-term exposure to low levels of lead (Pb(2+)) has been shown to produce behavioral deficits in rodents and humans by affecting ...
Reilly Carolyn Miller CM Nell Hodgson Woodruff School of Nursing, Emory University, 1520 Clifton Rd, NE #254, Atlanta, GA 30322, USA. - - 2013
Patients with cancer experience acute and chronic symptoms caused by their underlying disease or by the treatment. While numerous studies have examined the impact of various treatments on symptoms experienced by cancer patients, there are inconsistencies regarding the symptoms measured and reported in treatment trials. This article presents a systematic ...
Li Jing-Woei - - 2013
SUMMARY: Insertional mutagenesis from virus infection is an important pathogenic risk for the development of cancer. Despite the advent of high-throughput sequencing, discovery of viral integration sites and expressed viral fusion events are still limited. Here, we present ViralFusionSeq (VFS), which combines soft-clipping information, read-pair analysis, and targeted de novo ...
Takeuchi Hideki - - 2013
BACKGROUND: Because of its superior efficacy to tamoxifen, anastrozole has been widely used in Japan as an adjuvant treatment for postmenopausal, hormone-responsive breast cancer patients. However, anastrozole may affect bone in Japanese patients similar to its effects in Western patients. The aim of this study is to evaluate the rate ...
Pai Wan-Yu - - 2013
The activated cannabinoid receptor 1 (CB1R) is exclusively responsible for food intake and weight gain and regulates several pathological features associated with obesity in mammals. However, the precise role of CB1R in non-mammalian model systems is poorly understood. To investigate the functions of CB1R in zebrafish liver, we conditionally expressed ...
Sawano Yukari - - 2013
PURPOSE: The purpose of this study was to compare the dose-related effects of fentanyl on systemic hemodynamics, hormone release and cardiac output in response to endotracheal intubation in patients with and without hypertension. METHODS: Forty-five patients without hypertension and 45 patients with hypertension (total 90 patients) undergoing elective general surgical, ...
Zhao Yong-Jun - - 2013
The performance and temporal variation of hybrid vertical-subsurface flow constructed wetlands (VFCWs) in response to two-stage combinations of vertical upflow (VUF) and vertical downflow (VDF) were analyzed in this research. The results of high carbon (C) treatment and high nitrogen (N) treatment were similar. The Lythrum salicaria treatment showed higher ...
Neukamm Anke M C AM Department of Cardiology, Division of Medicine, Akershus University Hospital, Sykehusveien 27, Lørenskog 1478, Norway. - - 2013
To assess the distribution of high-sensitivity cardiac troponin T (hs-cTnT) concentrations in stable chronic obstructive pulmonary disease (COPD), and whether hs-cTnT is associated with pulmonary function. Prospectively designed, cross-sectional study. Outpatient clinic of Norwegian teaching hospital and community-based setting. Sample of 101 stable COPD patients from the hospital's outpatient clinic ...
Velasco Silvia - - 2013
Axon membrane glycoproteins are essential for neuronal differentiation, although the mechanisms underlying their polarized sorting and organization are poorly understood. We describe here that galectin-4 (Gal-4), a lectin highly expressed in gastrointestinal tissues and involved in epithelial glycoprotein transport, is expressed by hippocampal and cortical neurons where it is sorted ...
Cox Linda - - 2013
Allergen immunotherapy (AIT) is effective in reducing the clinical symptoms associated with allergic rhinitis, asthma and venom-induced anaphylaxis. Subcutaneous (SCIT) and sublingual immunotherapy (SLIT) with unmodified allergen extracts are the most widely prescribed AIT regimens. The efficacy of these 2 routes appears comparable, but the safety profile with SLIT is ...
Matsushima Hajime - - 2013
BACKGROUND: Prolonged hyperbilirubinemia (HB) following living donor liver transplantation (LDLT) can be a risk factor for early graft loss and mortality. However, some recipients who present with postoperative hyperbilirubinemia do recover and maintain a good liver function. AIM: The purpose of this study was to investigate the risk factors for ...
Kim Jon Jin - - 2013
OBJECTIVE: To analyse the demographics of children with moderate to severe chronic kidney disease (CKD) stages 3-5 over a 5-year period for the population of South East England. METHODS: Retrospective study of all children <18 years of age with estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m(2) managed at Evelina ...
Shi Jiyan - - 2013
Abstract The release of nanoparticles (NPs) to the environment poses an increasing potential threat to biological systems. This study investigated the phytotoxicity and accumulation of copper oxide (CuO) NPs to Elsholtzia splendens (a Cu-tolerant plant) under hydroponic conditions. The 50 % effective concentration (EC(50)) of CuO NPs to E. splendens ...
< 9 10 11 12 13 14 15 16 17 18 19 >