Search Results
Results 601 - 650 of 4440
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Basile Natalia - - 2013
Are the morphokinetics of growing embryos affected by the type of culture media utilized? Morphokinetic parameters used for embryo selection are not affected between the two different concept culture media analyzed. Studies on the effect of culture media on human embryos have focused on evaluating different in-house and commercially available ...
Meng Jianjun J College of Life Sciences, Anhui Normal University, Wuhu, 241000, - - 2013
Psychophysical studies on human and non-human vertebrate species have shown that visual contrast sensitivity function (CSF) peaks at a certain stimulus spatial frequency and declines in both lower and higher spatial frequencies. The underlying neural substrate and mechanisms remain in debate. Here, we investigated the role of primary visual cortex ...
Tamegai Hidenori - - 2013
The purpose of this study was to investigate whether intravenous (i.v.) administration allowed docetaxel to penetrate ascites in gastric cancer patients with peritoneal dissemination. Twelve patients with disseminated gastric carcinoma were enrolled in the study. All patients received docetaxel-containing drug regimens: i.v. administration of 40 mg/m(2) docetaxel in 6 patients, ...
Guira O - - 2013
This article is a contribution to improve the management of serodiscordant couples in Ouagadougou. The aim of the study was to explore sexuality and the risk for sexual transmission of HIV among serodiscordant couples followed-up in CHU-YO. The study consisted of a descriptive cross-sectional study conducted over 6 months, from ...
Ahsan Syed Y - - 2013
AIMS: Despite the increasing number of device implants worldwide, little is known about the early and late complications of cardiac resynchronisation therapy (CRT) or the incidence of these complications in patients with different heart failure aetiologies. We aim to determine procedural success and early and late complications in CRT patients.METHODS ...
Hudachek Susan F SF Department of Clinical Sciences, Animal Cancer Center, Colorado State University, Fort Collins, CO, USA. - - 2013
Lapatinib is an oral 4-anilinoquinazoline derivative that dually inhibits epidermal growth factor receptor and human epidermal growth factor receptor 2 (HER2). This drug is a mere decade old and has only been approved by the FDA for the treatment of breast cancer since 2007. Consequently, the intricacies of the pharmacokinetics ...
Shimatani Yasuhiko - - 2013
PURPOSE: To create and determine the clinical feasibility of a model based on dynamic computed tomography (CT) and a bolus injection of iodine contrast medium for evaluation of pulmonary perfusion for healthy individuals and for patients with lung diseases. MATERIALS AND METHODS: We analyzed pulmonary perfusion by means of dynamic ...
Lines J A - - 2013
A wide range of electronic dog training collars (e-collars) is available in the UK, but information enabling purchasers to compare the important characteristics of these collars is not available. In this research, the electrical characteristics of 13 e-collar models were examined, and an approach to ranking the strength of the ...
Rahif Mohammed - - 2013
Starting from ([Formula: see text]-1-trimethylsilyl-3-bromopenta-2,4-diene, a lithium-bromine exchange reaction followed by addition onto carbonyl compounds provided the corresponding dienyl alcohols. A Peterson-type [Formula: see text]-elimination promoted by a catalytic amount of trimethylsilyl triflate cross-conjugated gave triene systems ([3]dendralene) which rapidly reacted with the appropriate dienophiles to yield tandem intermolecular Diels-Alder ...
Alves João G - - 2013
Abstract Adolescent pregnancy is associated with low birth weight. This has been explained by socioeconomic or emotional factors. However, an adolescent's pelvis may not be completely developed and this can contribute to impairing fetal growth. Our aim was to compare the relationship between pelvic size and birth weight among adolescents ...
Ludovini V V Department of Medical Oncology, S. Maria Della Misericordia Hospital, 1, G. Dottori Street, 06132 Perugia, Italy. - - 2013
Insulin-like growth factor 1 receptor (IGF1R) represents a novel molecular target in non-small-cell-lung cancer (NSCLC). IGF1R and epidermal growth factor receptor (EGFR) activation are essential to mediate tumor cell survival, proliferation, and invasion. This study investigates the prognostic role of IGF1R and EGFR in surgically resected NSCLC. IGF1R and EGFR ...
Londero Lisiane G - - 2013
Long-chain polyunsaturated n-3 fatty acids (n-3 LCPUFAs) have hypolipidemic effects and modulate intermediary metabolism to prevent or reverse insulin resistance in a way that is not completely elucidated. Here, effects of these fatty acids on the lipid profile, phosphoenolpyruvate carboxykinase (PEPCK) activity, lipid synthesis from glucose in epididymal adipose tissue ...
Feng Huiyun - - 2013
Simplicity has made C. elegans pharyngeal development a particularly well-studied subject. Nevertheless, here we add the previously uncharacterised homeobox gene F20D12.6/ceh-19 to the set of transcription factor genes involved. GFP reporter assays revealed that ceh-19 is expressed in three pairs of neurons, the pharyngeal pace-maker neurons MC, the amphid neurons ...
Yuferov Vadim V Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, NY 10065, USA. - - 2013
Despite the successes of combination antiretroviral therapy, HIV-associated neurocognitive disorders persist in many infected individuals. Earlier studies showed that neurocognitive impairment was associated with glutamate toxicity and synaptodendritic damage. We examined alterations in expression of four ephrin genes that are involved in synapse formation and recruitment of glutamate receptors to ...
Miesfeldt Susan - - 2013
OPINION STATEMENT: Women with personal and family histories consistent with gynecologic cancer-associated hereditary cancer susceptibility disorders should be referred for genetic risk assessment and counseling. Genetic counseling facilitates informed medical decision making regarding genetic testing, screening, and treatment, including chemoprevention and risk-reducing surgery. Because of limitations of ovarian cancer screening, ...
Huntley Alyson L AL Centre of Academic Primary Care, School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, - - 2013
Case management is a collaborative practice involving coordination of care by a range of health professionals, both within the community and at the interface of primary and secondary care. It has been promoted as a way of reducing unplanned admissions in older people. The objective was to systematically review evidence ...
Sui Li - - 2013
Intracerebroventricular (ICV) administration of ouabain, a specific Na-K-ATPase inhibitor, in rats mimics the manic phenotypes of bipolar disorder and thus has been proposed as one of the best animal models of mania. Bipolar mania has been known to be associated with dysfunctions of medial prefrontal cortex (mPFC), a brain area ...
Yang Sung-Tae - - 2013
SUMMARYThe understanding of palatine vault growth in normal subjects is important to orthodontists. The aim of this study was to evaluate three dimensional (3D) longitudinal changes in the palatal vault from 6 to 14 years of age.Complete dental stone casts were biennially prepared for 50 subjects (25 girls and 25 ...
Funk William E - - 2013
Abstract Exposures to heavy metals during fetal and perinatal development are of particular concern. Yet, the health impacts of exposures to toxic metals during these early stages of human development are not well understood due to the paucity of in vivo human data. Dried blood spots (DBS), collected by public ...
Sessa Paola - - 2013
Using the event-related potential (ERP) approach, we tracked the time-course of White participants' empathic reactions to White (own-race) and Black (other-race) faces displayed in a painful condition (i.e., with a needle penetrating the skin) and in a non-painful condition (i.e., with Q-tip touching the skin). In a 280-340 ms time-window, ...
L Harrison - - 2013
BACKGROUND: There is a body of opinion in the clinical literature advocating the removal of intranasal contact points to treat facial pain. OBJECTIVES: To review the evidence that intranasal mucosal contact points cause facial pain or headache and their removal is therapeutic. TYPE OF REVIEW: Systematic review SEARCH STRATEGY: A ...
Elmadhoun Wadie M Y - - 2013
BACKGROUND: Infection with schistosomiasis and soil-transmitted helminthes (SSTH) constitutes a major health problem worldwide, yet the burden of disease is in the tropical countries. The disease is endemic in River Nile State, Sudan but the exact prevalence rate is unknown. METHODS: A survey of 2490 pupils in 103 basic schools ...
Goldstein Henry - - 2013
Abstract Parenting a child with chronic disease provides a unique set of challenges for both mothers and fathers throughout all phases of the illness. However, fathers of these children are under-represented in existing research. This review focuses on the fathers of children with chronic disease included in 44 original articles. ...
Swaminathan Anand - - 2013
Abstract Low-contrast retinal images have to be enhanced for good visual perception to aid in retinal vessel analysis. Classical sharpening enhancement techniques such as unsharp masking (USM) improve the contrast and bring out the information along with noise. This article uses a shift-invariant anisotropic Contourlet transform (CT) to decompose the ...
Gicquel Thomas - - 2013
A fast and sensitive liquid chromatography-tandem mass spectrometry (LC-MS-MS) method was developed and validated for the simultaneous determination of acetaminophen (APAP) and its glucuronide and sulfate metabolites (APAP-GLU and APAP-SUL) in small plasma volumes. This method included a simple step of sample preparation and a chromatographic separation on an LC-MS-MS ...
Chou Hsun-Hua HH Department of Psychiatry, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0804, - - 2013
Cognitive deficits contribute strongly to functional disability in schizophrenia. The cost of identifying and testing candidate procognitive agents is substantial. Conceivably, candidate drugs might be first identified by positive effects on cognitive domains in sensitive subgroups of healthy subjects. Here, we examined whether the MATRICS Consensus Cognitive Battery (MCCB) detected ...
Volodarsky Michael - - 2013
Autosomal recessive osteogensis imperfecta (OI) was diagnosed in three unrelated Israeli Bedouin consanguineous families. Fractures were evident in all cases in infancy. Genome wide linkage analysis ruled out association with any of the known osteogenesis imperfecta (OI) genes, and identified a single homozygosity locus of ∼2 Mb on chromosome 9 ...
Tang Michelle C W - - 2013
Post-translational modifications to residues in core histones convey epigenetic information. Their function can be evaluated in amino acid substitution mutants, although to date this method has not been used in mice. To this end, we have evaluated gene targeting vectors designed for Cre recombinase-mediated conditional allelic replacement at the two ...
Qi Yujuan - - 2013
During spermiogenesis, the manchette is an important structure for sperm head and tail formation. However, the mechanisms responsible for this process are poorly understood. In a previous study, we established a comparative proteome profile for mouse testis during the first wave of spermatogenesis, and provided lists of proteins of potential ...
Kajino Yoshitomo - - 2013
BACKGROUND: Hip resurfacing arthroplasty has some advantages, including improved metal-on-metal articulation, a lower dislocation rate and preserved femoral bone. This procedure is a surgical option for younger and more active patients with osteoarthritis and osteonecrosis of the femoral head. Although there have been some reports about the efficacy of this ...
Brown Brian - - 2013
PURPOSE: In this study we examine neuroretinal function in five amblyopes, who had been shown in previous functional MRI (fMRI) studies to have compromised function of the lateral geniculate nucleus (LGN), to determine if the fMRI deficit in amblyopia may have its origin at the retinal level. METHODS: We used ...
Suganthi Ramasamy - - 2013
Fifteen flavobacterium strains were isolated from raw chicken meat, raw goat meat and poultry soil in Coimbatore, Tamil Nadu. Most of the isolates developed yellow pigmented colonies with mucoid-spreading edges on food flavobacterium medium. The flavobacteria were Gram-negative rods and failed to produce indole and were non-fermentative. Moreover, they produced ...
Lucas Robyn - - 2013
Spatio-temporal patterns in sun exposure underlie variations in skin cancer incidence and vitamin D deficiency, indicate effectiveness of sun protection programs and provide insights into future health risks. From 558 adults across four regions of Australia (Brisbane (latitude 27ºSouth), Newcastle (33ºSouth), Geelong and the Western Districts of Victoria (37ºSouth) and ...
Munoz-Dávila M J - - 2013
We evaluated the use of urine specimens for direct identification and antibiotic testing of urinary tract pathogens using the Vitek system. A total of 343 urine specimens from patients with suspected UTI were selected by pyuria and screened by Gram staining to detect bacteriuria. Of those, 132 were analysed after ...
Tasanarong Adis - - 2013
BackgroundContrast-induced acute kidney injury (CI-AKI) increases the likelihood of patient morbidity and mortality following coronary procedures. Volume supplement with saline is the standard treatment to prevent CI-AKI. Additional antioxidant prophylaxis has often yielded conflicting results. The present study was conducted to examine the role of novel application vitamin E (tocopherol) ...
Fauchon F - - 2013
Papillary tumor of the pineal region (PTPR), recently described as a distinct clinicopathological entity, can show aggressive biological behavior. The optimal therapeutic approach of PTPR has not been well defined. The role of surgery, radiotherapy, and chemotherapy in the treatment of PTPR was analyzed in a large multicenter series. In ...
Al-Hussaini Ali - - 2013
Tonsillectomy is a common therapeutic option in the management of recurrent tonsillitis. In 1999, the Scottish Intercollegiate Guidelines Network (SIGN) introduced SIGN 34 outlining appropriate indications for tonsillectomy. Following concerns of increasing hospital admissions for tonsillitis, in 2009 ENT UK suggested that too few tonsillectomies were being undertaken. This study ...
Pilla Reddy Venkatesh - - 2013
High and variable placebo effect (PE) within and among clinical trials can substantially affect conclusions about the efficacy of new drugs in the treatment of schizophrenia and other neuropsychiatric disorders. In recent years, it has become increasingly difficult to prove drug efficacy against placebo, and one of the reasons is ...
Iavazzo Christos - - 2013
AIM: Female genital mutilation (FGM) is a common practice especially performed in women with no anaesthesia or antibiotics and in absence of aseptic conditions. The aim of this systematic review is to explore and analyze for first time in the current literature, the clinical evidence related to the presence of ...
Peker Tuncay - - 2013
Information about the distribution of intramuscular nerve fibres within the skeletal muscles will enhance the understanding of their morphological structure and functions. This study was designed to examine the entire intramuscular nerve distribution pattern in rat leg muscles. The tibialis cranialis, tibialis caudalis, extensor digitorum longus, flexor digitorum longus, gastrocnemius, ...
Stepto Nigel K - - 2013
What is the prevalence of insulin resistance (IR) and the contributions of intrinsic and extrinsic IR in women diagnosed with polycystic ovary syndrome (PCOS) according to the Rotterdam criteria? We report novel clamp data in Rotterdam diagnosed PCOS women, using World Health Organization criteria for IR showing that women with ...
Sakai Tsutomu - - 2013
OBJECTIVE: To evaluate the changes in health-related and vision-related quality of life (HR-QoL and VR-QoL) in patients with Behçet uveitis (BU) receiving infliximab therapy. METHODS: Twenty patients with recurrent BU attacks were enrolled. All patients were treated with infliximab. We evaluated the mean number of uveitis attacks and the mean ...
Kusz-Zamelczyk Kamila - - 2013
BACKGROUND: The Nanos gene is a key translational regulator of specific mRNAs involved in Drosophila germ cell development. Disruption of mammalian homologues, Nanos2 or Nanos3, causes male infertility in mice. In humans, however, no evidence of NANOS2 or NANOS3 mutations causing male infertility has been reported. Although Nanos1 seems dispensable ...
Zajdel Radosław R Department of Medical Informatics and Statistics, Faculty of Health Sciences, Medical University of Lodz, Łódź, Poland, - - 2013
Legislation systems of most countries prohibited using the handheld mobile phone while driving due to the fact that it disturbs concentration and causes hand involvement. Every phone owner is accustomed to the ringtone of his phone and almost involuntarily endeavors to pick it up or check who calls. This engages ...
Healy Donagh A - - 2013
BACKGROUND: Full-body CT scanning is increasingly being used in the initial evaluation of severely injured patients. We sought to analyse the literature to determine the benefits of full-body scanning in terms of mortality and length of time spent in the emergency department (ED). METHODS: A systematic search of the Pubmed ...
Vazquez Rodriguez Gabriela - - 2013
Angiogenesis has been considered an important target for cancer therapy. The inhibition of angiogenesis represents a promising strategy for anti-cancer treatment, tumor growth inhibition, and metastasis. Vasostatin 30 (Vs30), and the 14.1 kDa vasoinhibin (Vi-II-14.1) are two peptides with remarkable anti-tumor and anti-angiogenic effect. The aim of this study was to ...
Warschkow Rene - - 2013
While LRYGB has become a cornerstone in the surgical treatment of morbidly obese patients, concomitant cholecystectomy during LRYGB remains a matter of debate. The aim of this meta-analysis was to estimate the rate and morbidity of subsequent cholecystectomy after laparoscopic Roux-en-Y gastric bypass (LRYGB) in obese patients. A meta-analysis was ...
Clark Gary F GF Division of Reproductive Medicine and Fertility, and Division of Reproductive and Perinatal Research, Department of Obstetrics, Gynecology and Women's Health, University of Missouri School of Medicine, Columbia, MO 65212, USA. - - 2013
What is the role of carbohydrates in the binding of human sperm to the zona pellucida (ZP) and what are potential implications for pathogenesis? Both lectin-like and protein-protein interactions play an essential role in human gamete interactions. Studies in the mouse and human indicate a role for both lectin-like and ...
Van Gosen Bradley S - - 2013
Erionite, a mineral series within the zeolite group, is classified as a Group 1 known respiratory carcinogen. This designation resulted from extremely high incidences of mesothelioma discovered in three small villages from the Cappadocia region of Turkey, where the disease was linked to environmental exposures to fibrous forms of erionite. ...
Willemink Martin J - - 2013
OBJECTIVES: To explain the technical principles of and differences between commercially available iterative reconstruction (IR) algorithms for computed tomography (CT) in non-mathematical terms for radiologists and clinicians. METHODS: Technical details of the different proprietary IR techniques were distilled from available scientific articles and manufacturers' white papers and were verified by ...
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