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Li Xinrong - - 2013
ABSTRACT: BACKGROUND: Catgut implantation at acupoints has been used in China to treatment allergic rhinitis (AR) for a long time. However, its efficacy and safety in the treatment of AR is controversial due to the poor quality of the clinical trial of this therapy. This study aims to identify whether ...
Jiménez-Pavón David - - 2013
OBJECTIVE: To analyze the association between objectively assessed physical activity (PA) and markers of insulin resistance (IR) in European adolescents and to examine whether the association of objectively assessed PA and markers of IR is modified by cardiorespiratory fitness (CRF). METHODS: A cross-sectional study at school setting was conducted in ...
Korzeniecka-Kozerska Agata - - 2013
Abstract Objective. Myelomeningocele is the most common physically disabling birth defect in humans. It is caused by the failure of the neural tube to close and is most common in the lumbosacral area. Because of associated neurogenic bladder dysfunction, children with myelomeningocele have an increased risk of urinary tract infections ...
Morandini Piero - - 2013
Which factors limit metabolite accumulation in plant cells? Are theories on flux control effective at explaining the results? Many biotechnologists cling to the idea that every pathway has a rate limiting enzyme and target such enzymes first in order to modulate fluxes. This often translates into large effects on metabolite ...
Stessman Jochanan - - 2013
OBJECTIVES: To examine the relationship between resting pulse rate (RPR) and longevity in individuals aged 70 to 90. DESIGN: The Jerusalem Longitudinal Cohort Study (1990-2010) is a prospective longitudinal study of a representative cohort born in 1920-21. SETTING: Home-based comprehensive assessment in 1990, 1998, and 2005. PARTICIPANTS: Individuals aged 70 ...
Serna Eva - - 2013
BACKGROUND AND AIM: Increased basal release of nitric oxide (NO) in the splanchnic circulation contributes to elevated plasma levels of NO observed in decompensated cirrhosis. We evaluated in rat mesenteric arteries whether the differences in basal release of NO, revealed by asymmetric dimethylarginine (ADMA)- and N(G) -nitro-L-arginine methyl ester (L-NAME)-induced ...
Thyssen J P - - 2013
Ichthyosis vulgaris is caused by loss-of-function mutations in the filaggrin gene (FLG) and characterized clinically by xerosis, scaling, keratosis pilaris, palmar and plantar hyperlinearity, and a strong association with atopic disorders. According to published studies presented in this review article, FLG mutations are observed in approximately 7.7% of Europeans and ...
Shimada Tomohiro - - 2013
Peptidoglycan (PG), also designated as murein, forms a skeletal mesh within the periplasm of bacterial membrane. PG is a metabolically stable cell architecture in Escherichia coli, but under as yet ill-defined conditions, a portion of PG is degraded, of which both amino sugar and peptide moieties are either recycled or ...
Gomez Laura - - 2013
Selective oxidation of alkyl C-H bonds constitutes one of the highest challenges for chemical synthesis. In this work we show that mononuclear iron coordination complexes containing highly structured active sites catalyze the efficient oxidation of alkyl C-H bonds employing H2O2 as terminal oxidant. These catalysts are very reactive and can ...
Hino Shiori - - 2013
Linear Zn(ii)-Ce(iii)-Zn(ii) complex, which involves only one 4f electron as a spin source, behaves as an SMM. Easy-axis magnetic anisotropy for the ground (2)F(5/2) state of Ce(iii) was achieved by a uni-axial crystal field, which is formed with four phenoxo oxygens as axial donors with the other five oxygens as ...
Pichler Renate - - 2013
Abstract Objective. The aim of this study was to investigate the functional and oncological outcomes of orthotopic neobladders in women with urothelial cancer. Material and methods. From 1993 to 2007, 61 women underwent radical cystectomy and orthotopic ileal neobladder using the hemi-Kock pouch or Skinner T pouch. Sixteen of them ...
Morriss Richard - - 2013
Morriss R, Yang M, Chopra A, Bentall R, Paykel E, Scott J. Differential effects of depression and mania symptoms on social adjustment: prospective study in bipolar disorder. Bipolar Disord 2013: 15: 80-91. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd. Objectives:  Previous studies of social adjustment ...
Wang Zikun - - 2013
A novel Cu(ii)-catalyzed cyclization of α-diazo-β-oxoamides with amines has been developed, constituting a straightforward method to construct pyrrol-3(2H)-one rings. The intramolecular hydrogen bonding effect in α-diazo-β-oxoamides plays an essential role in this reaction. A plausible reaction mechanism involving divergent generation and subsequent [2 + 3] cyclization of ketene and α-diazoimine ...
Umesawa Mitsumasa - - 2013
Dietary behavior can worsen or prevent hypertension. However, data on the association between dietary behavior and the risk of hypertension in Asians are limited. The aim of this study was to determine these associations in Japanese male workers. We conducted a prospective study of 30-71-year-old Japanese male workers in Osaka, ...
Gopinath Bamini - - 2013
AIMS: Dietary modifications may play an important role in the prevention of diabetes. We aimed to assess the temporal association between diet quality and both impaired fasting glucose and Type 2 diabetes among older adults. METHODS: A total of 2564 participants aged 49+ years at baseline were examined between 1992 and ...
Gäbler Karoline - - 2013
The Janus kinase 2 mutant V617F occurs with high frequency in myeloproliferative neoplasms. Further mutations affecting the Janus kinase family have been discovered mostly in leukaemias and in myeloproliferative neoplasms. Owing to their involvement in neoplasia, inflammatory diseases and in the immune response, Janus kinases are promising targets for kinase ...
Ottaviani Daniela - - 2013
ABSTRACT Background: Retinoblastoma is a hereditary cancer of childhood caused by mutations in the RB1 tumor suppressor gene. An early diagnosis is critical for survival and eye preservation, thus identification of RB1 mutations is important for unequivocal diagnosis of hereditary retinoblastoma and risk assessment in relatives. Methods: We studied 144 ...
Cerutti Erika - - 2013
DPA-713 is the lead compound of a recently reported pyrazolo[1,5-a]pyrimidineacetamide series, targeting the translocator protein (TSPO 18 kDa), and as such, this structure, as well as closely related derivatives, have been already successfully used as positron emission tomography radioligands. On the basis of the pharmacological core of this ligands series, a ...
Zuo Lihua - - 2013
In this study, the enantioseparation of zopiclone, repaglinide, chlorphenamine maleate, brompheniramine maleate, dioxopromethazine hydrochloride, promethazine hydrochloride, liarozole, carvedilol, homatropine hydrobromide, homatropine methylbromide, venlafaxine, and sibutramine hydrochloride has been investigated using β-CD in combination with a chiral ionic liquid (IL), 1-ethyl-3-methylimidazolium-L-lactate. The influence of the type of IL and its concentration, ...
Byun Ju-Young - - 2013
A method has been developed for the direct conversion of DNA arrays into three dimensional protein arrays on a hydrogel matrix. An agarose gel embedded with bacterial protein synthesis machinery was used as the DNA-programmable expression gel matrix for the in situ translation of genes on a DNA array. Upon ...
Bolko Katarina - - 2013
Abstract Context: Despite its promising therapeutic activities, clinical use of resveratrol (RSV) is compromised with unfavorable biopharmaceutical properties, namely low water solubility. Objective: This work deals with improving RSV solubility and release rate through its incorporation in innovative mixed lipid phase self-microemulsifying drug delivery systems (SMEDDS). Methods: (Pseudo)ternary diagrams were ...
Kamar Rita - - 2013
Preterm infants admitted to the Neonatal Intensive Care Unit (NICU) often receive either umbilical- or peripheral arterial lines, for frequent blood sampling and monitoring arterial blood pressure. However, arterial lines can lead to severe complications [1] such as tissue ischemia and as a result necrosis of extremities. The consequences of ...
Kwon S H - - 2013
Background  Indole-3-acetic acid (IAA) is a newly introduced photosensitizer of photodynamic therapy (PDT) for acne, presenting sebum-reducing, anti-inflammatory and antimicrobial activity. Objective  This study was designed to evaluate the efficacy and safety of IAA-PDT in the treatment of facial seborrhoeic dermatitis. Method  In this prospective, single-blinded, 6-week trial, 23 patients ...
Almdahl Sven M - - 2013
Objectives. Comparison of figure-of-8 wiring or simple straight-wiring technique assessed by the frequency of early noninfectious sternal dehiscence. Design. Observational register study with 7835 patients having sternal closure with figure-of-8 steel wires was compared with 2122 patients, where the sternotomy was closed by simple interrupted straight wires. The endpoint was ...
Malti Abed - - 2013
BACKGROUND: In this paper, we propose a non-linear calibration method for hand-eye system equipped with a camera undergoing radial distortion as the rigid endoscope. Whereas classic methods propose either a separated estimation of the camera intrinsics and the hand-eye transform or a mixed non-linear estimation of both hand-eye and camera ...
Liba Benjamin D - - 2013
Exciting opportunities in bioelectronics will be facilitated by materials that can bridge the chemical logic of biology and the digital logic of electronics. Here we report the fabrication of a dual functional hydrogel film that can harvest electrons from its chemical environment and store these electrons by switching the film's ...
Sharma Purshotam - - 2013
The properties of natural, y- and yy-pyrimidines are compared using computational (B3LYP, MP2) methods. Ring expansion upon incorporation of benzene or naphthalene into the natural pyrimidines affects the preferred orientation of the base about the glycosidic bond in the corresponding nucleoside to a similar extent. Specifically, although the natural pyrimidines ...
Malheiros Silvia Rp - - 2013
ABSTRACT: BACKGROUND: Cerebral Palsy (CP) presents changes in posture and movement as a core characteristic, which requires multiprofessional clinical treatments during children's habilitation or rehabilitation. Besides clinical treatment, it is fundamental that professionals use evaluation systems to quantify the difficulties presented to the individual and their families in their daily ...
Wu Shu-Fang Vivienne - - 2013
The relationships between self-efficacy, self-care behavior, anxiety, and depression for Taiwanese individuals with type 2 diabetes were determined in this study. Depression and anxiety are common symptoms that can contribute toward adverse medical outcomes. A descriptive, cross-sectional, correlational design was used. The sample comprised 201 patients with type 2 diabetes ...
Arikanoglu Adalet - - 2013
ABSTRACT Multiple sclerosis (MS) is known to be influenced by various environmental factors including cigarette smoking. To identify the impact of smoking on conversion from clinically isolated syndrome (CIS) to clinically definite MS (CDMS), 95 consecutive uniformly-treated smoker (n = 31) and non-smoker (n = 64) CIS patients were evaluated ...
Rilo Esther - - 2013
We present experimental measurements of specific electrical (or ionic) conductivity of seven binary systems of 1-ethyl-3-methyl imidazolium alkyl sulfate (EMIM-CnS) with water or ethanol. Electrical conductivity was measured at 298.15 K in all range of concentrations, and selected mixtures also at 288.15 K, 308.15 K and 318.15 K. The alkyl ...
Taha Sheena Aislinn - - 2013
Swine flu (H1N1) reached pandemic proportions in 2009, yet ambivalence was met concerning intentions to be vaccinated. The present investigation determined predictors of perceived H1N1 contraction risk and vaccination intentions among Canadian adults (N = 1,027) responding to an online questionnaire. The relatively low rate of vaccination intent (30.12%, and 34.99% being ...
Mimeault Murielle - - 2013
Accumulating lines of experimental evidence have revealed that hypoxia-inducible factors, HIF-1α and HIF-2α, are key regulators of the adaptation of cancer- and metastasis-initiating cells and their differentiated progenies to oxygen and nutrient deprivation during cancer progression under normoxic and hypoxic conditions. Particularly, the sustained stimulation of epidermal growth factor receptor ...
Bang W J - - 2013
We evaluated the clinical efficacy and safety of the coadministration of a PDE5 inhibitor and an α-adrenergic blocker in patients with both benign prostatic hyperplasia/lower urinary tract symptoms (BPH-LUTS) and ED using mirodenafil 50 mg (Mvixx) once daily (OD) in patients already receiving stable α-blocker therapy. This study was a prospective, ...
Pedersen Vivi Kathrine - - 2013
Landscapes modified by glacial erosion show a distinct distribution of surface area with elevation (hypsometry). In particular, the height of these regions is influenced by climatic gradients controlling the altitude where glacial and periglacial processes are the most active, and as a result, surface area is focused just below the ...
Tang Dianping - - 2013
Recent research has looked to develop innovative, powerful and novel biofunctionalized nanoparticles, controlling and tailoring their properties in a very predictable manner to meet the needs of clinic immunoassays in the biomedical field. This minireview briefly summarizes recent advances covering the last 3 years, exploiting nanoparticle-based electrochemical, optical, mass-sensitive, colorimetric ...
Kraemer Helena Chmura - - 2013
No one treatment is likely to affect all patients with a disorder in the same way. A treatment highly effective for some may be ineffective or even harmful for others. Statistically significant or not, the effect sizes of many treatments tend to be small. Consequently, emphasis in clinical research is ...
Neff K J - - 2013
ABSTRACT: Obesity is recognized as a global health crisis. Bariatric surgery offers a treatment that can reduce weight, induce remission of obesity-related diseases, and improve the quality of life. In this article, we outline the different options in bariatric surgery and summarize the recommendations for selecting and assessing potential candidates ...
Papadimitriou Dimitrios T - - 2013
BACKROUND: With the recent knowledge of the possible involvement of 1,25-dihydroxyvitamin D in the pathogenesis of Type 1 Diabetes (T1D) and the results of its administration in animal models, we conducted a clinical trial by treating high-risk children, positive in autoantibodies for T1D, with oral calcitriol. METHODS: This prospective trial ...
Castaldelli-Maia João Mauricio - - 2013
Considering the absence of data on the appearance of drugs other than alcohol and tobacco in movie scenes, we decided to study the prevalence of portrayal of illicit drug use in a convenience sample of 50 Brazilian Movies. A total of 192 scenes (12h49'03(″)) meeting the inclusion criteria were identified ...
Gieler Uwe - - 2013
The terminology, classification, diagnosis and treatment of self-inflicted dermatological lesions are subjects of open debate. The present study is the result of various meetings of a task force of dermatologists, psychiatrists and psychologists, all active in the field of psychodermatology, aimed at clarifying the terminology related to these disorders. A ...
Isbell Forest - - 2013
Although nutrient enrichment frequently decreases biodiversity, it remains unclear whether such biodiversity losses are readily reversible, or are critical transitions between alternative low- and high-diversity stable states that could be difficult to reverse. Our 30-year grassland experiment shows that plant diversity decreased well below control levels after 10 years of chronic ...
Yasmin Nighat - - 2013
The epithelial signaling protein and transcriptional regulator β-catenin has recently been implicated in hematopoietic dendritic cell (DC) differentiation as well as in DC-mediated tolerance. We here observed that epidermal Langerhans cells (LCs) but not interstitial/dermal DCs express detectable β-catenin. LCs are unique among the DC family members in that LC ...
Daly Susan M - - 2013
The assessment of vascular dynamics has been shown to yield both qualitative and quantitative metrics and thus play a pivotal role in the diagnosis and prognosis of various diseases, which may manifest as microcirculatory irregularities. Optical Coherence Tomography (OCT) is an established imaging modality which utilises the principle of optical ...
Chase Elaine - - 2013
This article considers the relevance of the notion of ontological security - a sense of order, stability, routine and predictability to life - to contemporary conceptualisations of wellbeing. Drawing on in-depth interviews with unaccompanied young people seeking asylum in the UK, it demonstrates how a positive sense of self and ...
Lee Hyunhwa - - 2013
This paper explored the relationships between parental alcoholism, sense of belonging, resilience, and depressive symptoms among Koreans in the U.S. Data from 206 Koreans (Mean age = 28.4 years; 59.8% females) living in a Midwestern state were collected in 2009, using a web-based survey, which included Children of Alcoholic Screening Test, ...
Ryan Daniel A - - 2013
A water-soluble deep cavitand recognized alkylammonium salts, including the drug amantadine hydrochloride, in spiked samples of human urine. The signals of the guests are detected by (1)H NMR upfield of 0 ppm and so occur in a spectroscopic window that is outside of the normal region and distinct from the ...
Wedekind Dirk - - 2013
ABSTRACT: BACKGROUND: Insecure early attachment experiences have been reported to play an important role in the manifestation in alcoholism. The purpose of this study was to investigate the relationship of attachment styles with anxiety, anxiety coping and dysfunctional personality styles, as well as with the prevalence of personality disorders, and ...
Debarbieux S - - 2013
BACKGROUND: New primary melanomas arising in stage IV melanoma patients under BRAF inhibitors have been recently reported. This raises the question of the nature of the earliest cellular events identifiable within pre-existing moles. Objectives: to use RCM to investigate changing moles in patients under Vemurafenib. METHODS: In the first part ...
Reiter Jakub - - 2013
New ionic liquids with an asymmetric anion, fluorosulfonyl-(trifluoromethanesulfonyl)imide (FTFSI), were prepared and their chemical-physical properties were investigated. The ionic liquids based on N-methyl-N-propylpyrrolidinium, PYR(13), N-butyl-N-methylpyrrolidinium, PYR(14), and N-methoxyethyl-N-methylpyrrolidinium, PYR(12O1), exhibit high electrochemical stability (>5.5 V on platinum) and thermal stability (>250 °C in N(2) and >200 °C in O(2)). Due ...
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