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Abusleme Loreto L Division of Periodontology, Department of Oral Health and Diagnostic Sciences, The University of Connecticut Health Center, Farmington, CT, - - 2013
The goals of this study were to better understand the ecology of oral subgingival communities in health and periodontitis and elucidate the relationship between inflammation and the subgingival microbiome. Accordingly, we used 454-pyrosequencing of 16S rRNA gene libraries and quantitative PCR to characterize the subgingival microbiome of 22 subjects with ...
Vaske Jamie - - 2013
The current study uses data from the genetic subsample from the National Longitudinal Study of Adolescent Health (Add Health) in waves I and II (ages of 11-19 and 12-20 respectively) to investigate the interaction of the TaqIA polymorphism and poor parental socialization on changes in adolescent marijuana use. Results reveal ...
Cosmidis J - - 2013
Micrometer-sized spherical and rod-shaped forms have been reported in many phosphorites and often interpreted as microbes fossilized by apatite, based on their morphologic resemblance with modern bacteria inferred by scanning electron microscopy (SEM) observations. This interpretation supports models involving bacteria in the formation of phosphorites. Here, we studied a phosphatic ...
Liu Xiao-Jin - - 2013
Hypertrophic scarring is a common disease affecting millions of people around the world, but there are currently no satisfactory drugs to treat the disease. Exaggerated inflammation and mechanical stress have been shown to be two main mechanisms of excessive fibrotic diseases. Here we found that a benzopyran natural product, xiamenmycin, ...
Hodak Emmilia - - 2013
Studies of associated cancer in patients with mycosis fungoides (MF) have focused primarily on secondary cancers in North American and European populations. This study investigated the association between MF and malignancies, anxiety and depression in the Israeli population. Data on Israeli patients with MF and age- and gender-matched controls were ...
Hong Kyung-Won - - 2013
Low albumin:globulin (A/G) ratios are associated with vascular adverse events, nephrotic syndrome and autoimmune disease. Genome-wide association studies (GWASs) have been identifying genetic variants associated with total serum protein, serum albumin and globulins, but A/G ratio has never been considered the target phenotype. To identify the genetic basis of the ...
Chung W S - - 2013
Factors related to sexual arousal are different in men and women. The conditions for women to become aroused are more complex. However, the conventional audio-visual stimulation (AVS) materials used to evaluate sexual arousal are universal. In the present study, we investigated sexual differences in the response to different types of ...
Koelsch Bertram L - - 2013
We combined the high MR signal enhancement achieved using dissolution dynamic nuclear polarization (DNP) with a pulsed gradient double spin echo diffusion MR sequence to rapidly and accurately measure the diffusion coefficients of various hyperpolarized (13)C molecules in solution. Furthermore, with a diffusion-weighted imaging sequence we generate diffusion coefficient maps ...
Parcq J - - 2013
BACKGROUND: Thrombolysis using tissue plasminogen activator (tPA) is the only treatment approved for acute ischemic stroke. Although tPA is an efficient clot lysis enzyme, it also produces damage of the neurovascular unit including hemorrhagic transformations and neurotoxicity. OBJECTIVES: Based on the mechanism of action of tPA on neurotoxicity, we aimed ...
Liu Hailong - - 2013
Many haloarchaea are known as polyhydroxyalkanoates (PHAs) producers, but a global and integrated view of the PHA biosynthesis is still lacking in this group of archaea. In this study, a combined proteomic and transcriptomic approach was employed in Haloarcula hispanica, a model haloarchaeon that accumulates poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) under nutrient-limiting conditions ...
Carmichael R J - - 2013
Equine herpes myeloencephalopathy, resulting from equine herpes virus type 1 (EHV-1) infection, is associated with substantial morbidity and mortality in the horse. As compared to other antiviral drugs, such as acyclovir, ganciclovir has enhanced potency against EHV-1. This study investigated the pharmacokinetics of ganciclovir and its oral prodrug, valganciclovir, in ...
Fawcett Jonathan M - - 2013
In a novel event method directed forgetting task, instructions to Remember (R) or Forget (F) were integrated throughout the presentation of four videos depicting common events (e.g., baking cookies). Participants responded more accurately to cued recall questions (E1) and true/false statements (E2-4) regarding R segments than F segments. This was ...
Michalska Anna - - 2013
INTRODUCTION Diabetic macular edema is a common cause of visual acuity deterioration among patients with diabetes. Laser photocoagulation is a still most common treatment techniques of diabetic retinopathy and diabetic macular edema. OBJECTIVES To assess mean retinal sensitivity among patients with diabetic macular edema before and after laser photocoagulation treatment. ...
Kosicka K - - 2013
11β-Hydroxysteroid dehydrogenase type 2 (11β-HSD2) catalyzes the inactivation of cortisol (F) to cortisone (E) in aldosterone target tissues, thereby protects mineralocorticoid receptor from F. Failure of 11β-HSD2 function is the basis of apparent mineralocorticoid excess, and its mild disturbances are suggested to lead to hypertension. The aim of the study ...
Gulpers Math J M - - 2013
OBJECTIVES: To assess the long-term effects of the EXBELT intervention program, which was designed to reduce belt restraint use and was found to be effective immediately after implementation, after 24 months. DESIGN: Quasi-experimental longitudinal design. SETTING: Thirteen nursing homes: seven assigned to control group and six to intervention group. PARTICIPANTS: A ...
Bloomgarden Zachary - - 2013
Various aspects of lifestyle are associated with the development of obesity, including physical activity, cigarette use (and its cessation), alcohol, television watching, computers, and sleep. Dietary factors are particularly important, both those leading to weight gain, such as starches, meats, fats, and sugar-sweetened beverages, and those contributing to weight maintenance ...
Zielinski Andrzej - - 2013
Objective. The aim of this study was to investigate how distance to hospital and socioeconomic status (SES) influence the use of secondary health care (SHC) when taking comorbidity into account. Design and setting. A register-based study in Östergötland County. Subjects. The adult population of Östergötland County. Main outcome measures. Odds ...
Eshah Nidal F - - 2013
Risk factor reduction and modification of patient lifestyle have become the focus of secondary prevention and cardiac rehabilitation programs. Considering the scarcity of resources in developing countries, nurses can potentially provide great benefit to acute coronary syndrome patients by utilizing hospital time to teach the patients how to lower their ...
Rusznák Zoltán - - 2013
Giant cells of the cochlear nucleus are thought to integrate multimodal sensory inputs and participate in monaural sound source localization. Our aim was to explore the significance of a hyperpolarization-activated current in determining the activity of giant neurones in slices prepared from 10 to 14-day-old rats. When subjected to hyperpolarizing ...
Hosseini Seyyed Vahide - - 2013
Parents are likely to be key influences on children's physical activity behaviors, although it is not clear how. This study was designed to explore parents' roles in Iranian adolescent girls' physical activity habit development. A qualitative study was conducted by means of semistructured one-to-one interviews with 25 participants, including 16 ...
Kuper-Hommel Marion J J - - 2013
ABSTRACT Population-based series analyzing clinical implications of nodal versus extranodal presentation of marginal zone lymphoma(MZL) are lacking. We studied clinical differences and trends in incidence, therapy and survival of nodal and extranodal MZL, and of MZL at different extranodal sites, in a population-based cohort. All patients with localized (AAS I&II) ...
Pupelli G - - 2013
BACKGROUND: small diameter melanocytic lesions represent a diagnostic challenge for clinicians since they do not follow the ABCD rule and do not always display reliable histopathologic criteria OBJECTIVES: The aim of the study was to analyze the confocal features of small diameter lesions (naevi and melanomas with diameter ≤ 5 ...
Green Mandy C - - 2013
The work in this article describes a spectral signature for the detection of a C(α) radical damaged peptide, which should enable the use of infrared spectroscopic methods to directly monitor oxidative events. Spectra for radical damaged peptides are computed with ab initio methods. The amide bands A, I, II, and ...
Perrin Andrea - - 2013
This review aims to introduce the chemistry of low dosage inhibitors of clathrate hydrate formation within the context of their role in the oil and gas industry. The review covers both kinetic hydrate inhibitors and anti-agglomerants from the point of view of structure-function relationships, focussing on recent refinements in mechanistic ...
Kojima Akira - - 2013
BACKGROUND/AIMS: The Japan Society for Dialysis Therapy established "Guidelines for the Treatment of Hepatitis C Virus Infection in Dialysis Patients". We evaluated the status of HCV infection and the treatment of hemodialysis patients in Gunma prefecture. METHODS: Questionnaires concerning the infection rate, recognition of the guidelines, and treatment status were ...
Moskovits Martin - - 2013
SERS is some 35 years old, and the subject of over 11 000 articles. The field of Plasmonics, and large aspects of Metamaterials are clearly based on concepts that became current as a result of SERS. Despite this, a number of persistent, fuzzy ideas about the origin of the enhancement in ...
Lucconi Giulia - - 2013
Abstract Extracts of Crataegus monogyna Jacq. (hawthorn) show an interesting free radical scavenging (FRS) effect, related to their flavonoids content. Unfortunately, their oral administration is affected by their low bioavailability. The aim of this work is to obtain a multiparticulate drug delivery system for hawthorn extracts for oral administration. The ...
Nasit Jitendra Gordhanbhai - - 2013
Astroblastoma is a rare primary glial tumor of children and young adults. Radiologically astroblastoma presents as a large well-circumscribed supratentorial, solid-cystic heterogeneous mass. Histology shows perivascular pseudorosettes with hyalinization. Only a single case has been reported with signet-ring-like cell morphology. Signet-ring morphology in primary central nervous system tumors is exceedingly ...
Zhang Xi-Mei - - 2013
The aim of this study was to analyze outcomes in adult patients with early stage systemic anaplastic large cell lymphoma (ALCL) treated with doxorubicin-based chemotherapy and radiotherapy. Forty-six adult patients with early stage systemic ALCL received chemotherapy followed by radiotherapy. All patients except two received chemotherapy with CHOP (cyclophosphamide, doxorubicin, ...
Verburg F A - - 2013
Aim: The objective of this study was to assess the feasibility, dosimetry, tolerability and efficacy of systemically administrated p-[131I]iodo-L-phenylalanine (131IPA) combined with hypo-fractionated external beam radiation therapy (EBRT) in patients with recurrent glioblastoma multiforme (GBM). Patients, methods: Five patients (2 women, 3 men, aged 27-69) with recurrent GBM and exhaustion ...
Robinson Matthew R - - 2013
Acquisition and allocation of resources are central to life-history theory. However, empirical work typically focuses only on allocation despite the fact that relationships between fitness components may be governed by differences in the ability of individuals to acquire resources across environments. Here, we outline a statistical framework to partition the ...
Wong Ka-Chun - - 2013
Drynaria fortunei (Kunze) J. Sm. (DF), a Chinese herb commonly used for the treatment of bone fracture, was previously shown to exert anabolic effects on bone. However, its active ingredients as well as the mechanisms of action are far from clear. The present study aimed to characterise the bone anabolic ...
Tylko Grzegorz - - 2013
A Monte Carlo simulation was used to determine geometry correction factors that increase accuracy of quantitative X-ray microanalysis of laterally semithick biological materials. A model composed of cellulose with homogeneously distributed biological elements and lateral dimensions between 0.5-25 μm was chosen. The specimen was exposed to 5, 10, and 15 ...
Hou Chengyi - - 2013
We report a Cu(2)O nanocrystal-reduced graphene oxide hybrid that is dispersible in water and has anticancer activity under both visible and near-infrared light irradiation. In contrast to the highly efficient killing of both normal and cancer cells initiated by the photothermal effect, the photocatalytic effect of this material results in ...
Liu Ming - - 2013
Dual E- and H-field control of microwave performance with enhanced ferromagnetic resonance (FMR) tunability has been demonstrated in microwave composites FeGaB/PZN-PT(011). A voltage-impulse-induced non-volatile magnetization switching was also realized in this work, resulting from the hysteretic type of phase transition in PZN-PT(011) at high electric fields. The results provide a ...
Chen Ling - - 2013
Plants are one of the most economical platforms for large-scale production of recombinant proteins for biopharmaceutical and industrial uses. A large number of human recombinant proteins of therapeutic value have been successfully produced in plant systems. One of the main technical challenges of producing recombinant proteins in plants is to ...
Ribeiro José A - - 2013
In this work, the ion transfer mechanism of anticancer drug daunorubicin (DNR) at a liquid/liquid interface has been studied for the first time. This study was carried out using electrochemical techniques namely cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The lipophilicity of DNR was investigated at the water/1,6-dichlorohexane (DCH) ...
Menting John G JG Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, - - 2013
Insulin receptor signalling has a central role in mammalian biology, regulating cellular metabolism, growth, division, differentiation and survival. Insulin resistance contributes to the pathogenesis of type 2 diabetes mellitus and the onset of Alzheimer's disease; aberrant signalling occurs in diverse cancers, exacerbated by cross-talk with the homologous type 1 insulin-like ...
Trussardi Fayh Ana Paula - - 2013
Evidence supports an important contribution of abdominal obesity and inflammation to the development of insulin resistance (IR) and CVD. Weight loss in obese individuals can reduce inflammation and, consequently, IR, but the role of training remains unclear. The aim of this study was to evaluate the effects of body weight ...
Stavri Simona - - 2013
Dermal bone is an important component of the teleost fins, and its ability to regenerate after fin amputation appears to be unlimited. The organic bone matrix contain type I collagen fibers, proteoglycans enriched in chondroitin sulfate, and noncollagenous matrix protein such as osteocalcin, osteopontin, and osteonectin. These molecules are synthesized ...
Liu Guanshu G F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, - - 2013
Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast mechanism that is well suited for molecular imaging studies. This new mechanism can be used to detect small amounts of contrast agent through the saturation of rapidly exchanging protons on these agents, allowing a wide range of applications. ...
Morona Judy K - - 2013
BACKGROUND: Effective off-loading is considered to be an important part of the successful clinical management of people with diabetes, as between 15% and 25% of them will suffer from a foot ulcer during their lifetime. The aim of this systematic review is to investigate the safety and effectiveness of different ...
Josuttis Melanie - - 2013
Strawberry cultivars grown at different locations in Europe showed genotype- and environment-dependent variation in total phenol and anthocyanin content. This study focused on the compositional diversity of tannins from these cultivars using a high-through-put liquid-chromatography-mass-spectrometric (LCMS) technique. Cultivars grown in Germany showed differences in the relative amounts of proanthocyanidins (PACs) ...
Sarkar Siddharth - - 2013
Smokeless tobacco use is a major health issue but has received less attention in craving research. The present non-funded study aimed to assess craving associated with smokeless tobacco compared to smoked forms. Forty-eight nicotine dependent male subjects attending a deaddiction center in India were recruited. The subjects were exposed to ...
Xin Wuhong - - 2013
The binary alloy system Si(x)Ge(1-x) provides a continuous series of materials with gradually varying properties. In this paper, we report on a fundamental basis a method to make large-area macroporous Si(x)Ge(1-x) films with variable Ge content by electrodeposition in an ionic liquid, with SiCl(4) and GeCl(4) as precursors. The chemical ...
James Andre E - - 2013
Protein-conjugated gold nanoparticles (AuNPs) have been extensively explored for the development of many novel protein assays. In this article, we demonstrate that nanoparticle tracking analysis (NTA) can be used as a rapid and simple analytical tool to monitor bioconjugation and to study protein-protein interactions. The adsorption of protein A onto ...
Pace Vittorio - - 2013
The chemoselective α-iodination of various simple and multi-functionalised acrylic esters is efficiently accomplished by a Morita-Baylis-Hillman protocol involving the use of N-iodophthalimide, 3-quinuclidinol and KF-Celite in acetonitrile. No degradation of the obtained compounds was observed under the optimized conditions thus, furnishing α-iodoacrylates suitable for organometallic reactions (i.e. Nozaki-Kishi-Hiyama type coupling).
Houchi Hakim H Groupe de Recherche sur l'Alcool & les Pharmacodépendances, INSERM ERi, UFR de Pharmacie, Université de Picardie Jules Verne, France. - - 2013
There is emerging evidence that the adenosinergic system might be involved in drug addiction and alcohol dependence. We have already demonstrated the involvement of A2A receptors (A2AR) in ethanol-related behaviours in mice. Here, we investigated whether the A2AR agonist CGS 21680 can reduce ethanol operant self-administration in both non-dependent and ...
Lan C-C E - - 2013
BACKGROUND: Atopic dermatitis (AD) is a commonly encountered inflammatory skin disease. Although acute lesions of acute AD are characterized by intense inflammation, the hallmarks of chronic AD lesions include lichenified fibrosis and thickening of the upper dermis. The increased expression of transforming growth factor beta 1 (TGF-β1), a well-known fibrogenic ...
Romancino Daniele P - - 2013
The sea urchin provides a relatively simple and tractable system for analyzing the early stages of embryo development. Here, we use the sea urchin species, Paracentrotus lividus, to investigate the role of Alix in key stages of embryogenesis, namely the egg fertilization and the first cleavage division. Alix is a ...
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