Search Results
Results 201 - 250 of 3055
< 1 2 3 4 5 6 7 8 9 10 >
Anne Sorensen - - 2013
OBJECTIVES: The purpose of this study was to investigate changes in human placental oxygenation during maternal hyperoxia by using the non-invasive blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) technique. METHODS: Eight healthy pregnant women in gestational week 28 to 36 were included in the study. By using a ...
Pankewitz F - - 2013
BACKGROUND: The prevalence of onychomycosis has increased steadily in the last decade. An accurate diagnosis at the outset is important for successful and cost-effective treatment of patients. However, current diagnostic tests for onychomycosis are neither rapid nor sensitive nor specific. OBJECTIVES: Therefore, we developed a microsatellite-based PCR-ELISA (MS-ELISA) assay for ...
von Heideken Johan - - 2013
AIM: To investigate how sociodemographic factors relate to the risk femur shaft fractures in children, and how the relationship differs by gender and age. METHODS: Population based case-control study. Swedish children (n=1,874), 0-14 years of age, with a femur shaft fracture diagnostic code occurring between 1997 and 2005 were selected ...
Yonezawa Tetsu - - 2013
Surface-assisted laser desorption/ionization time-of-flight mass spectrometry (SALDI-TOF-MS) using GaP nanoparticles (NPs) prepared by a gas evaporation method was investigated on poly(ethylene glycol)s (PEGs). The mass spectra of PEG and survival yield measurements suggested that larger GaP NPs have a quite high soft ionization ability.
Pinton Giulia - - 2013
Malignant Pleural Mesothelioma (MMe) is a rare but increasingly prevalent, highly aggressive cancer with poor prognosis. The aetiology of MMe is essentially a function of previous exposure to asbestos fibres, which are considered to be an early-stage carcinogen. Asbestos is toxic to human mesothelial cells (HMCs), that activate the nuclear ...
Xu Y - - 2013
The performance of a fast optical computed tomography (CT) scanner based on a point laser source, a small area photodiode detector, and two optical-grade Fresnel lenses is evaluated. The OCTOPUS™-10× optical CT scanner (MGS Research Inc., Madison, CT) is an upgrade of the OCTOPUS™ research scanner with improved design for faster motion ...
Rochon Paula A - - 2013
OBJECTIVES: To understand how drug therapy differently affects older women and men. DESIGN: Population-based, retrospective cohort study. SETTING: Ontario, Canada. PARTICIPANTS: Twenty-one thousand five hundred twenty-six older adults (13,760 women, 7,766 men) with dementia newly started on oral atypical antipsychotic therapy between April 1, 2007, and March 1, 2010. MEASUREMENTS: ...
Zhai Yanling - - 2013
We report a novel design, based on a combination of lanthanide-doped upconversion nanoparticles and polyoxometalates, for electrically controlled fluorescence switches and sensitive detection of antioxidants in aqueous solution.
Comelon M - - 2013
BACKGROUND: Targiniq®, an oxycodone prolonged-release (PR) formulation combined with the opioid antagonist naloxone PR, aims to prevent opioid-induced constipation without impairing the analgesic efficacy. This has been confirmed during prolonged use in chronic pain or cancer patients. The purpose of our study was to compare clinical effects of oxycodone PR ...
Julia Chantal - - 2013
Inflammation mediates several chronic diseases. Micronutrients can act on inflammation, either through modulating cytokine production or by scavenging by-products of activated white cells. Identifying dietary patterns (DP) reflecting these mechanisms and relating them to inflammation is of interest. The objective of the study was to identify DP specifically associated with ...
Fenenga Christine J - - 2013
The challenges faced by African countries that have pioneered a national health insurance scheme (NHIS) and the lessons learned can be of great value to other countries, contemplating the introduction of such a health financing system. In 2003, Ghana initiated the NHIS to provide access to healthcare for people in ...
Turkowicz Monika Joanna - - 2013
The article discusses analytical problems related to the determination of coenzyme Q10 in biological samples. The assaying of coenzyme Q10 in complex samples, such as plasma, tissues, or food items requires meticulous sample preparation prior to final quantification. The process typically consists of the following steps: deproteinization, extraction, and ultimately ...
Lees Justin G - - 2013
Precise orchestration of actin polymer into filaments with distinct characteristics of stability, bundling, and branching underpins cell migration. A key regulator of actin filament specialization is the tropomyosin family of actin-associating proteins. This multi-isoform family of proteins assemble into polymers that lie in the major groove of polymerized actin filaments, ...
Wang J-J - - 2013
The mammalian cyclin-dependent kinase subunit (Cks) family has two members, Cks1 and Cks2. Overexpression of Cks1 and Cks2 has been reported to be associated with high aggressiveness and poor prognosis in several malignancies, including prostate and hepatocellular carcinomas. However, whether Cks1 and Cks2 are overexpressed in esophageal carcinoma remains uncharacterized. ...
Jørgensen Anne - - 2013
Testicular germ cell tumours (TGCT) of young adults arise from the intratubular precursor, carcinoma in situ (CIS). CIS cells are thought to be developmentally arrested and transformed fetal germ cells that survive through childhood and gain invasive capacity after puberty. Given that germ cell neoplasms arise frequently in undervirilised and ...
Pereira L C - - 2013
Brominated flame retardants are used in various consumer products to increase their resistance to fire and/or high temperatures. Polybrominated Diphenyl Ethers (PBDEs) are representatives of this class and among the most widely used congeners, and BDE-100 is produced on a large scale. There is a lack of toxicological data about ...
O'Kelly Julian - - 2013
In the behavioural assessment of disorders of consciousness (DOC), best practice is for several different assessment tools to be used to encourage a variety of different responses indicative of awareness. Anecdotal evidence suggests a range of musical stimuli may be particularly effective in eliciting responses to guide the assessment process, ...
Wang Ying - - 2013
OBJECTIVE: Idiopathic short stature (ISS) refers to extreme short stature without any diagnostic explanation. Recently, three genome-wide association studies discovered associations between the ZBTB38 and adult height in different populations. Therefore, variations in the ZBTB38 might contribute to ISS. Therefore, one study in Korea population showed that ZBTB38 gene was ...
Sfaihi Lamia - - 2013
The aim of this study is to review the cases of arterial ischemic stroke (AIS) in children in our department to evaluate the clinical and neuroimaging features, the etiologies and the treatment. This study retrospectively reviewed the records of all children aged between 1 month and 16 years who were admitted ...
Benzler Jonas - - 2013
The hypothalamus has been identified to be a main insulin target tissue for regulating normal body weight and glucose metabolism. Recent observations suggest that c- Jun-N-terminal kinase (JNK)-signalling plays a crucial role in the development of obesity and insulin resistance since neuronal JNK-1 ablation in the mouse prevented high fat ...
Momose Kenji - - 2013
Necl-2/CADM1 is down-regulated by the promoter hypermethylation and/or the loss of heterozygosity at chromosome 11q23.2 in many types of cancers and serves as a tumor suppressor by interacting in cis with ErbB3 and suppressing the ligand-induced ErbB2/ErbB3 signaling for cell movement and death. However, the incidence of these epigenetic and ...
Trussardi Fayh Ana Paula - - 2013
Evidence supports an important contribution of abdominal obesity and inflammation to the development of insulin resistance (IR) and CVD. Weight loss in obese individuals can reduce inflammation and, consequently, IR, but the role of training remains unclear. The aim of this study was to evaluate the effects of body weight ...
Stavri Simona - - 2013
Dermal bone is an important component of the teleost fins, and its ability to regenerate after fin amputation appears to be unlimited. The organic bone matrix contain type I collagen fibers, proteoglycans enriched in chondroitin sulfate, and noncollagenous matrix protein such as osteocalcin, osteopontin, and osteonectin. These molecules are synthesized ...
Morona Judy K - - 2013
BACKGROUND: Effective off-loading is considered to be an important part of the successful clinical management of people with diabetes, as between 15% and 25% of them will suffer from a foot ulcer during their lifetime. The aim of this systematic review is to investigate the safety and effectiveness of different ...
Josuttis Melanie - - 2013
Strawberry cultivars grown at different locations in Europe showed genotype- and environment-dependent variation in total phenol and anthocyanin content. This study focused on the compositional diversity of tannins from these cultivars using a high-through-put liquid-chromatography-mass-spectrometric (LCMS) technique. Cultivars grown in Germany showed differences in the relative amounts of proanthocyanidins (PACs) ...
Sarkar Siddharth - - 2013
Smokeless tobacco use is a major health issue but has received less attention in craving research. The present non-funded study aimed to assess craving associated with smokeless tobacco compared to smoked forms. Forty-eight nicotine dependent male subjects attending a deaddiction center in India were recruited. The subjects were exposed to ...
Cosmidis J - - 2013
Micrometer-sized spherical and rod-shaped forms have been reported in many phosphorites and often interpreted as microbes fossilized by apatite, based on their morphologic resemblance with modern bacteria inferred by scanning electron microscopy (SEM) observations. This interpretation supports models involving bacteria in the formation of phosphorites. Here, we studied a phosphatic ...
Liu Xiao-Jin - - 2013
Hypertrophic scarring is a common disease affecting millions of people around the world, but there are currently no satisfactory drugs to treat the disease. Exaggerated inflammation and mechanical stress have been shown to be two main mechanisms of excessive fibrotic diseases. Here we found that a benzopyran natural product, xiamenmycin, ...
Hodak Emmilia - - 2013
Studies of associated cancer in patients with mycosis fungoides (MF) have focused primarily on secondary cancers in North American and European populations. This study investigated the association between MF and malignancies, anxiety and depression in the Israeli population. Data on Israeli patients with MF and age- and gender-matched controls were ...
Hong Kyung-Won - - 2013
Low albumin:globulin (A/G) ratios are associated with vascular adverse events, nephrotic syndrome and autoimmune disease. Genome-wide association studies (GWASs) have been identifying genetic variants associated with total serum protein, serum albumin and globulins, but A/G ratio has never been considered the target phenotype. To identify the genetic basis of the ...
Chung W S - - 2013
Factors related to sexual arousal are different in men and women. The conditions for women to become aroused are more complex. However, the conventional audio-visual stimulation (AVS) materials used to evaluate sexual arousal are universal. In the present study, we investigated sexual differences in the response to different types of ...
Liu Chao - - 2013
The oxidant controlled palladium catalysed selective oxidation of primary alcohols to aldehydes or esters was investigated. The electronic properties of the benzylic alcohols and the structure of the oxidant are both important factors in controlling the selectivity between aldehydes and esters. A covalent benzyl ligand derived from BnCl provides η(3) ...
Hayashi Tsuyoshi - - 2013
BACKGROUND AND AIM: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an established diagnostic method for patients with suspected pancreatic ductal carcinoma (PDC). Rapid on-site evaluation (ROSE) has been reported to improve the accuracy. However, an on-site cytopathologist is not routinely available in many institutions. One of the solutions may be ...
Slusarz Magdalena J - - 2013
Vasopressin and oxytocin receptors belong to the superfamily of G protein-coupled receptors and play an important role in many physiological functions. They are also involved in a number of pathological conditions being important drug targets. In this work, four vasopressin analogues substituted at position 2 with 3,3'-diphenylalanine have been docked ...
Cabrales Antonio - - 2013
This paper studies price determination in pharmaceutical markets using data for 25 countries, 6 years, and a comprehensive list of products from the MIDAS IMS database. A key finding is that the USA has prices that are not significantly higher than those of countries with similar income levels, especially those that ...
Mognetti Barbara - - 2013
Prostate cancer frequently metastasizes to the bone, and the interaction between cancer cells and bone microenvironment has proven to be crucial in the establishment of new metastases. Bone marrow mesenchymal stem cells (BM-MSCs) secrete various cytokines that can regulate the behaviour of neighbouring cell. However, little is known about the ...
Nasit Jitendra Gordhanbhai - - 2013
Solid pseudopapillary tumor (SPT) is an uncommon pancreatic neoplasm with low malignant potential. It occurs predominantly in young women. It is very rare in males and nonrelated pediatrics. In children, SPT commonly present as abdominal mass and pain. A 10-year-old male presented with progressively growing palpable tumor in upper abdomen. ...
Martino Alessandro - - 2013
The exposure to pesticides and toxic compounds in xenobiotic transport and metabolism genes has been shown to affect risk of developing multiple myeloma (MM). Therefore, we hypothesized that genetic variations in xenobiotic transport and metabolism regulator genes PXR (NR1I2) and CAR (NR1I3) could determine a difference in MM susceptibility. Ten ...
Gambichler T - - 2013
We read with great interest the paper of Edmonds et al. (1) who observed that men with penile lichen sclerosus (PLS) have significantly increased extracellular matrix protein 1 (ECM1) serum levels when compared to healthy controls (HC). Similar results were previously found in women with vulvar LS (VLS).(2) Edmonds et ...
Steyer Véronique - - 2013
Once considered potential sources of danger, generating industrial risks, companies are now viewed as indispensable partners in preparing risk responses. However, this shift raises the crucial question of the coordination between the various actors, especially as the literature - particularly on public-private partnerships (PPPs) and inter-organisational collaborations - highlights multiple ...
Kagiyama Megumi - - 2013
Strigolactones (SLs) are plant hormones that inhibit shoot branching. DWARF14 (D14) inhibits rice tillering and is an SL receptor candidate in the branching inhibition pathway, whereas the close homologue DWARF14-LIKE (D14L) participates in the signaling pathway of karrikins (KARs), which are derived from burnt vegetation as smoke stimulants of seed ...
Scott Daniel J - - 2013
ABSTRACT: BACKGROUND: The Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC-II) database is a free, publicresource for intensive care research. The database was officially released in 2006, and has attracted agrowing number of researchers in academia and industry. We present the two major software toolsthat facilitate accessing the relational database: ...
Jang Ji Woong - - 2013
BACKGROUND AND AIM: Comparatively little is known about acute pancreatitis or acute recurrent pancreatitis (AP/ARP) with intraductal papillary mucinous neoplasm of the pancreas (IPMN) as the causative lesion although there have been many reports about the malignant potential of IPMN as a premalignant lesion. METHODS: From 2000 to 2008, in ...
Whiteoak Christopher J - - 2013
An aluminium complex based on an amino triphenolate ligand scaffold shows unprecedented high activity (initial TOFs up to 36,000 h-1), substrate scope and functional group tolerance in the formation of highly functional organic carbonates prepared from epoxides and CO2. The developed catalytic protocol is further characterized by low catalyst loadings ...
Tunca Yusuf - - 2013
The coincidence of trisomy 21 and a structural rearrangement is very rare, and even it has not been reported as a prenatal diagnosis yet. In this article, we present an autosomal translocation carrier fetus with trisomy 21: 47,XX,+21, t(3;8)(p21;q24). Although the coincidence of reciprocal translocation and trisomy may be seen ...
Vera-Ramirez Laura - - 2013
Liver diseases pose a major medical problem worldwide and a wide variety of herbs have been studied for the management of liver-related diseases. In this respect, curcumin has long been used in traditional medicine, and in recent years it has been the object of increasing research interest. In combating liver ...
Orihuela Ruben - - 2013
Abstract The carcinogen inorganic arsenic (iAs) undergoes biomethylation (BMT) in some cells. The methylated metabolite, monomethylarsonous (MMA(3+)), may cause oxidative DNA damage (ODD). With chronic iAs exposure, BMT-competent cells show ODD while BMT-deficient do not. To further define these events, we studied ODD produced by acute iAs or MMA(3+) in ...
Riek Alexander - - 2013
A large number of analyses have examined how basal metabolic rate (BMR) is affected by body mass in mammals. By contrast, the critical ambient temperatures that define the thermo-neutral zone (TNZ), in which BMR is measured, have received much less attention. We provide the first phylogenetic analyses on scaling of ...
Sariyildiz M A - - 2013
The aim of this study was to explore the impact of ankylosing spondylitis (AS) and the disease-related variables, psychological status and the quality of life on the female patients' sexual function measured according to the Female Sexual Function Index (FSFI). Thirty-seven sexually active female AS patients and 33 healthy controls ...
Bai Yu - - 2013
AIM: Recently Gastroesophageal Reflux Disease Questionnaire (GerdQ) has been developed for diagnosis of GERD. However, no study investigated its value in real-world practice. This study aimed to investigate whether GerdQ can be used for diagnosis of GERD in China. METHODS: A national multicenter survey was undertaken; all patients who underwent ...
< 1 2 3 4 5 6 7 8 9 10 >