Search Results
Results 201 - 250 of 3064
< 1 2 3 4 5 6 7 8 9 10 >
Masri Leila - - 2013
The Red Queen hypothesis proposes that coevolving parasites select for outcrossing in the host. Outcrossing relies on males, which often show lower immune investment due to, for example, sexual selection. Here, we demonstrate that such sex differences in immunity interfere with parasite-mediated selection for outcrossing. Two independent coevolution experiments with ...
Julia Chantal - - 2013
Inflammation mediates several chronic diseases. Micronutrients can act on inflammation, either through modulating cytokine production or by scavenging by-products of activated white cells. Identifying dietary patterns (DP) reflecting these mechanisms and relating them to inflammation is of interest. The objective of the study was to identify DP specifically associated with ...
Friman Hen H Department of Chemical Engineering and Biotechnology, Ariel University Center, Ariel, 40700, - - 2013
A microbial fuel cell (MFC) was operated with a pure culture of Cupriavidus basilensis bacterial cells growing in the anode compartment in a defined medium containing acetate or phenol. Operating this mediator-less MFC under a constant external resistor of 1 kΩ with acetate or phenol led to current generation of ...
Fenenga Christine J - - 2013
The challenges faced by African countries that have pioneered a national health insurance scheme (NHIS) and the lessons learned can be of great value to other countries, contemplating the introduction of such a health financing system. In 2003, Ghana initiated the NHIS to provide access to healthcare for people in ...
Turkowicz Monika Joanna - - 2013
The article discusses analytical problems related to the determination of coenzyme Q10 in biological samples. The assaying of coenzyme Q10 in complex samples, such as plasma, tissues, or food items requires meticulous sample preparation prior to final quantification. The process typically consists of the following steps: deproteinization, extraction, and ultimately ...
Lees Justin G - - 2013
Precise orchestration of actin polymer into filaments with distinct characteristics of stability, bundling, and branching underpins cell migration. A key regulator of actin filament specialization is the tropomyosin family of actin-associating proteins. This multi-isoform family of proteins assemble into polymers that lie in the major groove of polymerized actin filaments, ...
Wang J-J - - 2013
The mammalian cyclin-dependent kinase subunit (Cks) family has two members, Cks1 and Cks2. Overexpression of Cks1 and Cks2 has been reported to be associated with high aggressiveness and poor prognosis in several malignancies, including prostate and hepatocellular carcinomas. However, whether Cks1 and Cks2 are overexpressed in esophageal carcinoma remains uncharacterized. ...
Jørgensen Anne - - 2013
Testicular germ cell tumours (TGCT) of young adults arise from the intratubular precursor, carcinoma in situ (CIS). CIS cells are thought to be developmentally arrested and transformed fetal germ cells that survive through childhood and gain invasive capacity after puberty. Given that germ cell neoplasms arise frequently in undervirilised and ...
Pereira L C - - 2013
Brominated flame retardants are used in various consumer products to increase their resistance to fire and/or high temperatures. Polybrominated Diphenyl Ethers (PBDEs) are representatives of this class and among the most widely used congeners, and BDE-100 is produced on a large scale. There is a lack of toxicological data about ...
Parker J - - 2013
Mohs micrographic surgery (MMS) is acknowledged as the gold-standard treatment for high risk non-melanoma skin cancer of the head and neck. By virtue of its tissue-sparing nature, patients who undergo MMS may require several stages or 'layers' to successfully extirpate a tumour. Under such circumstances it is commonplace for adhesive ...
Cortés-Sol Albertina - - 2013
ABSTRACT: BACKGROUND: The role of the endothelial cell (EC) in blood flow regulation within the central nervous system has been little studied. Here, we explored EC participation in morphological changes of the anterior hypothalamic paraventricular nucleus (PVN) microvasculature of female rats at two reproductive stages with different metabolic demand (virginity ...
Murley G S - - 2013
The aim of this study was to investigate the association between foot type and the morphometry of selected muscles and tendons of the lower limb. Sixty-one healthy participants (31 male, 30 female; aged 27.1 ± 8.8 years) underwent gray-scale musculoskeletal ultrasound examination to determine the anterior-posterior (AP) thickness of tibialis anterior, tibialis ...
Zhou Heying - - 2013
We previously reported 2 osteoporosis-susceptibility genes--formiminotransferase N-terminal sub-domain containing gene (FONG) and thrombospondin, type 1, domain-containing 7A (THSD7A)--in which we identified two common single-nucleotide polymorphisms, rs7605378 (FONG) and rs12673692 (THSD7A). The former was associated with a predisposition to osteoporosis and the latter with bone mineral density. To further elucidate the ...
Speakman John R - - 2013
Summary During famines females generally have a mortality advantage relative to males, and the highest levels of mortality occur in the very young and the elderly. One popular hypothesis is that the sex differential in mortality may reflect the greater body fatness combined with lower metabolism of females, which may ...
Almouhawis Hanan A - - 2013
Wegener's granulomatosis (WG) is an idiopathic, systemic inflammatory disease characterized by necrotizing granulomatous inflammation and pauci-immune small-vessel vasculitis of upper and lower respiratory tract and kidneys. The condition affects both genders equally, although some inconsistent gender differences have been observed. The aetiology of WG remains unknown although a number of ...
Batista M - - 2013
Objective. Venlafaxine is a bicyclic antidepressant that may be associated with severe cardiotoxicity following large overdose. The purpose of this short case series is to present different patterns of venlafaxine-related cardiotoxicity and to discuss the potential mechanisms. Case series. Between January 2010 and July 2011, four patients were admitted to ...
Taddei Marco - - 2013
The synthesis of the first water stable isoreticular phosphonate based mixed-linker metal-organic frameworks (MOFs) is achieved via the use of the N-donor heterocyclic co-ligands. Furthermore, these isoreticular phosphonate frameworks show selective CO(2)/N(2) uptake at low pressures.
Laureau Constance - - 2013
R. glacialis leaves were tested for their PTOX content and electron flow to photorespiration and to alternative acceptors. In shade-leaves, the PTOX and NDH content were markedly lower than in sun-leaves. Carbon assimilation/light and C(i) response curves were not different in sun- and shade-leaves but photosynthetic capacity was the highest ...
Rinaldi Fabrizio - - 2013
BACKGROUND.-: Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) and trigeminal neuralgia (TN) are unilateral painful conditions that can share the same triggering factors, autonomic features and the main location, as well as the cyclically recurrent crises. Both these syndromes are associated with a high percentage of findings ...
Wise Matt P - - 2013
ABSTRACT: Improving the quality of oral hygiene is recognised as an important counter measure for reducing the incidence of ventilator-associated pneumonia amongst critically ill patients. Toothbrushing physically disrupts the dental plaque that acts as a reservoir for pulmonary infection and therefore has the potential to reduce the incidence of ventilator-associated ...
Jang Sori - - 2013
Eleven spontaneous mutations of acetyl-CoA carboxylase have been identified in many herbicide-resistant populations of 42 species of grassy weeds, hampering application of aryloxyphenoxypropionate, cyclohexadione and phenylpyrazoline herbicides in agriculture. IC(50) shifts (resistance indices) caused by herbicide-resistant mutations were determined using a recombinant yeast system that allows comparison of the effects ...
Yoon Cho Sung - - 2013
Prader-Willi syndrome (PWS) is a genetic disorder caused by the absence of expression of the paternal copy of maternally imprinted genes in chromosome region 15q11-13. The genetic subtypes of PWS are classified into deletion (∼70%), maternal uniparental disomy (mUPD; 25-30%), imprinting center defects (3-5%) and rare unbalanced translocations. Recently, Matsubara ...
Zimmerman Amy E AE Department of Ecology and Evolutionary Biology, University of California Irvine, CA 92697, USA. - - 2013
Understanding the relationship between prokaryotic traits and phylogeny is important for predicting and modeling ecological processes. Microbial extracellular enzymes have a pivotal role in nutrient cycling and the decomposition of organic matter, yet little is known about the phylogenetic distribution of genes encoding these enzymes. In this study, we analyzed ...
Oram S H SH Department of Haematology, Cambridge Institute for Medical Research and Wellcome Trust and MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, - - 2013
LMO1 is a transcriptional regulator and a T-acute lymphoblastic leukaemia (T-ALL) oncogene. Although first identified in association with a chromosomal translocation in T-ALL, the ectopic expression of LMO1 occurs far more frequently in the absence of any known mutation involving its locus. Given that LMO1 is barely expressed in any ...
Léauté-Labrèze C - - 2013
Since our report of the ability of propranolol to shrink alarming infantile hemangiomas (IHs) (1,2), propranolol has become the first line therapy for life threatening IHs (3-5). Recently, a randomized clinical trial versus placebo has confirmed the safety and efficacy of 2mg/kg daily oral propranolol in children aged between 9 ...
Licata P - - 2013
Forty-seven samples of milk taken from goat and ovine farms in Calabria (southern Italy) between April and May 2010 were analysed. Analyses were carried out by ion chromatography (ICS 1000; Dionex). For method validation, RSDs (%) on retention times and on peak area were determined by considering a mixture of ...
Rismo Renathe - - 2013
Abstract Objective. To investigate mucosal cytokine gene expression levels in healed mucosa after anti-tumor necrosis factor (TNF) therapy in patients with Crohn's disease (CD) as possible risk factors for relapse after discontinuation of therapy. Design. Thirty-seven CD patients treated with anti-TNF agents until complete mucosal healing, documented by endoscopy, discontinued ...
Koga Haruka - - 2013
Micropatterning is useful for regulating culture environments. We developed a highly efficient near-infrared-(NIR)-responsive gel and established a new technique that enables cell patterning by NIR irradiation. As a new culture substratum, we designed a tissue culture plate that was coated with a composite gel composed of agarose and carbon nanotubes ...
Vinci Giuliana - - 2013
Liquid-liquid microextraction coupled to LC with fluorescence detection for the determination of Environmental Protection Agency's 16 priority pollutant polycyclic aromatic hydrocarbons in rainwater has been developed. The optimization of the extraction method has involved several parameters, including the comparison between an ultrasonic bath and a magnetic stirrer as extractant apparatus, ...
Jain Mayur V - - 2013
The rapid accumulation of knowledge on apoptosis regulation in the 1990s was followed by the development of several experimental anticancer- and anti-ischaemia (stroke or myocardial infarction) drugs. Activation of apoptotic pathways or the removal of cellular apoptotic inhibitors has been suggested to aid cancer therapy and the inhibition of apoptosis ...
Riley Richard D - - 2013
We describe methods for meta-analysis of randomised trials where a continuous outcome is of interest, such as blood pressure, recorded at both baseline (pre treatment) and follow-up (post treatment). We used four examples for illustration, covering situations with and without individual participant data (IPD) and with and without baseline imbalance ...
Zhai Peng - - 2013
Tissue engineering scaffolds are designed not only to provide structural support for the repair of damaged tissue, but can also serve the function of bioactive protein delivery. Here we present a study on the preparation and characterization of protein-loaded microspheres, either alone or incorporated into mock tissue scaffolds, for sustained ...
El-Dakdoky Mai H - - 2013
Abstract The aim of this study was to investigate the consequences of exposure to three levels of boric acid on male rats reproduction, fertility, and progeny outcome, with emphasis on testicular DNA level and quality. ِAdult male rats (12 weeks old) were treated orally with 125, 250 and 500 mg/kg ...
Fernández-Gómez Beatriz B Department of Marine Biology and Oceanography, Institut de Ciències del Mar, Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, - - 2013
Bacteroidetes are commonly assumed to be specialized in degrading high molecular weight (HMW) compounds and to have a preference for growth attached to particles, surfaces or algal cells. The first sequenced genomes of marine Bacteroidetes seemed to confirm this assumption. Many more genomes have been sequenced recently. Here, a comparative ...
Daniele Gennaro - - 2013
Capecitabine , an oral prodrug of 5-fluorouracil (5-FU), is adsorbed in its intact form through the intestine and metabolized to 5-FU in tumour cells. In metastatic breast cancer (MBC), capecitabine is an effective and well-tolerated therapeutic option both in monotherapy and in combination with chemotherapeutic or molecular-targeted agents. We summarized ...
Lago Paola - - 2013
BACKGROUND: National and international guidelines have been published on pain control and prevention in the newborn, but data on compliance with these guidelines are lacking. AIM: To document current hospital practices for analgesia at neonatal intensive care units (NICUs) 5 years after national guidelines were published in Italy. METHODS: A computer-based ...
Deng Zhipeng - - 2013
Brazilin is a major homoisoflavonoid component isolated from the dried heartwood of traditional Chinese medicine Caesalpinia sappan L., which is a natural red pigment used for histological staining. Herein a sensitive, specific and rapid analytical LC-MS/MS method was established and validated for brazilin in rat plasma. After a simple step ...
Evans Benjamin A - - 2013
The naturally transformable bacterium Streptococcus pneumoniae is able to take up extracellular DNA and incorporate it into its genome. Maintaining natural transformation within a species requires that the benefits of transformation outweigh its costs. Although much is known about the distribution of natural transformation among bacterial species, little is known ...
Mujico Jorge R - - 2013
Consumption of a high-fat diet (HFD), which is associated with chronic 'low-grade' systemic inflammation, alters the gut microbiota (GM). The aim of the present study was to investigate the ability of an oleic acid-derived compound (S1) and a combination of n-3 fatty acids (EPA and DHA, S2) to modulate both ...
Feng Ruopeng - - 2013
Transcriptional factor Sox2 is essential for regulation of self-renewal and homeostasis of neural stem cells (NSCs) during brain development. However, the downstream targets of Sox2 and the underlying molecular mechanism are largely unknown. In this study, we found that Sox2 directly up-regulates the expression of survivin, which inhibits the mitochondria-dependent ...
Richard-Devantoy S - - 2013
OBJECTIVE: To compare cognitive inhibition performance between people with early-onset (EOD) or late-onset depression (LOD) and controls, and between women and men with LOD. METHODS: On the basis of a case-control design, global executive performance (Frontal Assessment Battery); verbal (Hayling), attention (Stroop), and motor (Go/No-Go) components of cognitive inhibition; mental ...
Blache Y - - 2013
Arm swing helps to increase vertical jump height (VJH), in part by a greater hip joint muscle work. The force-velocity relationship has been put forward to explain the increase in hip joint work. Nevertheless, the efficacy ratio, muscle shortening length, and active state might be parameters that affect the effective ...
Kobayashi Yuka - - 2013
A single crystal of anilinium tetrathiafulvalene-2-carboxylate exhibits a characteristic electrical conduction; it is a semiconductor with activation-type transport above 200 K; σ(rt) = 0.16 S cm(-1) with an activation energy of 0.11 eV. On the other hand, below 200 K, it does not obey the Arrhenius relation but is conductive ...
Teng Xu - - 2013
Background: Eosinophilic gastroenteritis (EG) is an increasingly recognized inflammatory disease characterized by gastrointestinal (GI) symptoms and eosinophilic infiltration of the GI tract. Serosal form is one subtype of EG. The aetiology and pathogenesis of EG are unknown and the diagnosis and treatment properly are difficult for physician. Methods: A retrospective ...
Xuan Yan - - 2013
Based on increasing evidence from animal and human studies, vitamin D deficiency is now regarded as a potential risk factor for type 2 diabetes (T2D). Vitamin D is involved in the pathogenesis of pancreatic β-cell dysfunction, insulin resistance and systemic inflammation, conditions that contribute to the development of T2D. Vitamin ...
Shiomi1 Daisuke - - 2013
RodZ interacts with MreB and both factors are required to maintain the rod shape of Escherichia coli. The assembly of MreB into filaments regulates the subcellular arrangement of a group of enzymes that synthesizes the peptidoglycan (PG) layer. However, it is still unknown how polymerization of MreB determines the rod ...
Liba Benjamin D - - 2013
Exciting opportunities in bioelectronics will be facilitated by materials that can bridge the chemical logic of biology and the digital logic of electronics. Here we report the fabrication of a dual functional hydrogel film that can harvest electrons from its chemical environment and store these electrons by switching the film's ...
Sharma Purshotam - - 2013
The properties of natural, y- and yy-pyrimidines are compared using computational (B3LYP, MP2) methods. Ring expansion upon incorporation of benzene or naphthalene into the natural pyrimidines affects the preferred orientation of the base about the glycosidic bond in the corresponding nucleoside to a similar extent. Specifically, although the natural pyrimidines ...
Malheiros Silvia Rp - - 2013
ABSTRACT: BACKGROUND: Cerebral Palsy (CP) presents changes in posture and movement as a core characteristic, which requires multiprofessional clinical treatments during children's habilitation or rehabilitation. Besides clinical treatment, it is fundamental that professionals use evaluation systems to quantify the difficulties presented to the individual and their families in their daily ...
Wu Shu-Fang Vivienne - - 2013
The relationships between self-efficacy, self-care behavior, anxiety, and depression for Taiwanese individuals with type 2 diabetes were determined in this study. Depression and anxiety are common symptoms that can contribute toward adverse medical outcomes. A descriptive, cross-sectional, correlational design was used. The sample comprised 201 patients with type 2 diabetes ...
< 1 2 3 4 5 6 7 8 9 10 >