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Kao Ming-Wei - - 2013
Pulmonary sequestration is a congenital anomaly of the lungs. We present the case of a patient whose initial symptom was mild dysphagia. Esophagoscopy showed the presence of a submucosal tumor in the lower-third section of the esophagus. The tumor was excised via video-assisted thoracoscopic surgery. The histopathology results indicated extrapulmonary ...
Kumar Archana - - 2013
BACKGROUND: The high-cure rates of 90% in retinoblastoma are not replicated in developing countries due to late presentation and poor compliance to treatment. The present study takes a closer look at causes of abandonment of therapy and effectiveness of counselling in reducing abandonment. PROCEDURE: A retrospective study of children with ...
Konofaos P - - 2013
Peripheral nerve injury may result in injury without gaps or injury with gaps between nerve stumps. In the presence of a nerve defect, the placement of an autologous nerve graft is the current gold standard for nerve restoration. The clinical employment of tubes as an alternative to autogenous nerve grafts ...
Shuhaimi-Othman Mohammad - - 2013
Two freshwater fish, Rasbora sumatrana (Cyprinidae) and Poecilia reticulata (guppy; Poeciliidae), were exposed to a range of eight heavy metals (copper (Cu), cadmium (Cd), zinc (Zn), lead (Pb), nickel (Ni), iron (Fe), aluminium (Al), and manganese (Mn)) at varied concentrations for 96 h in the laboratory. Mortality was assessed and ...
Mosleh Othman - - 2013
Choroid plexus carcinoma (CPC) is a rare central nervous system malignant tumor with a dismal prognosis, especially in the case of incomplete resection or recurrence. The authors report long-term survival of a 1-year-old patient with recurrent CPC and Li-Fraumeni syndrome with surgical resection and high-dose chemotherapy (HDC) consisting of single ...
Shin Seo Hwa - - 2013
OBJECTIVES: HG1 is an antimicrobial peptide derived from halocidin, which is naturally found in tunicates. The purpose of this study was to evaluate the therapeutic potential of HG1 as a novel antifungal agent for treating oral candidiasis. METHODS: The pharmacokinetic properties of HG1 were explored in mice, which were orally ...
Balajonda Naraida - - 2013
BACKGROUND:A top priority for research studies is to ensure that potential participants receive adequate information to make a truly informed decision. Understanding patient experiences with the recruitment process may identify areas for improvement in the consent process. We examined which factors were associated with the decision to consent in a ...
Vance J T - - 2013
Insects are attractive models for the development of micro-aerial vehicles (MAVs) due to their relatively simple sensing, actuation and control architectures as compared to vertebrates, and because of their robust flight ability in dynamic and heterogeneous environments, characterized by turbulence and gusts of wind. How do insects respond to gust ...
Braam Katja I - - 2013
Background In pediatric cancer patients scars of totally implantable venous access devices (TIVAD) are often widened and hypertrophic. This study report on the prevalence and deviation of abnormal scarring in children with a TIVAD and to describe the influencing factors for this abnormal scarring. Methods In a cross-sectional study scars ...
- - 2013
The Fourth National Consensus Conference on the management of Helicobacter pylori (H. pylori) infection organized by Chinese Medical Association, Chinese Society of Gastroenterology and co-sponsored by Jiangxi Medical Association was held at Jinggangshan, Jiangxi Province on April 26-27, 2012. More than 40 members of the study group on Helicobacter pylori ...
Arango Duque Guillermo - - 2013
Synaptotagmins (Syts) are a group of type I membrane proteins that regulate vesicle docking and fusion in processes such as exocytosis and phagocytosis. All Syts possess a single transmembrane domain, and two conserved tandem Ca(2+)-binding C2 domains. However, Syts IV and XI possess a conserved serine in their C2A domain ...
Botello Igor - - 2013
Three barbiturate drugs, barbital, phenobarbital, and secobarbital were separated and analyzed by electrokinetic supercharging. The influence of different parameters on electrokinetic supercharging performance was evaluated using both univariated and multivariated optimization processes. The parameters studied were sample pH, concentration, and length of the leading and terminating electrolytes, electrokinetic injection of ...
Malcolm Glenna M - - 2013
Much of the current knowledge on population biology and ecology of soilborne fungal pathogens has been derived from research based on populations recovered from plants displaying disease symptoms or soil associated with symptomatic plants. Many soilborne fungal pathogens are known to cause disease on a large number of crop plants, ...
Su Shu-Jem - - 2013
Caffeine consumption reportedly influences bone mineral density and body weight. However, the effects of caffeine on bone metabolism are still controversial, and whether the dosage of caffeine influences osteogenic differentiation is yet to be clarified. In the present study, we cultured primary adipose-derived stem cells (ADSCs) and a bone marrow ...
Pariani Elena - - 2013
The activity and circulation of influenza viruses in Lombardy - Northern Italy - (a region with nearly 10 out of the 60 million inhabitants of Italy) were investigated during two consecutive seasons (2010-2011 and 2011-2012), as part of the Italian Influenza Surveillance Network. The molecular characteristics of the hemagglutinin (HA) ...
Ruiz José - - 2013
A series of new organoiridium(III) complexes [Ir(N-C)(2)(N-S)]Cl (HN-C = 2-phenylpyridine (Hppy), N-S = methyl thiosemicarbazide (1), phenyl thiosemicarbazide (2) and naphtyl thiosemicarbazide (3)) have been synthesized and characterized. The crystal structure of (1) has been established by X-ray diffraction, showing the thiosemicarbazide ligand bound to the iridium atom as N,S-chelate. ...
Duan Wentao - - 2013
We report a silver orthophosphate microparticle system showing collective behaviors in aqueous medium. Transition between two emergent patterns, namely "exclusion" and "schooling", can be triggered by shift in chemical equilibrium upon the addition or removal of ammonia, or in response to UV light. The transitions are consistent with a self-diffusiophoresis ...
Kuzmina Zoya - - 2013
Bronchiolitis obliterans syndrome (BOS), pathognomonic for chronic graft-versus-host disease (cGVHD) of the lung, is a progressive and often fatal complication after allogeneic hematopoietic cell transplantation (HCT). Biomarkers for prediction and diagnosis of BOS are urgently needed to improve patients' prognosis. We prospectively evaluated B-cell subpopulations and B-cell activating factor (BAFF) ...
Honaas Loren A - - 2013
ABSTRACT: BACKGROUND: Orobanchaceae is the only plant family with members representing the full range of parasitic lifestyles plus a free-living lineage sister to all parasitic lineages, Lindenbergia. A generalist member of this family, and an important parasitic plant model, Triphysaria versicolor regularly feeds upon a wide range of host plants. ...
Muthukumar Yazh - - 2013
Myriaporone 3/4, a cytotoxic polyketide, has been reported as an inhibitor of eukaryotic protein synthesis. However, the mechanism by which it inhibits translation was unknown. Here we show that myriaporone 3/4 stalls protein synthesis in the elongation phase by inducing phosphorylation of eukaryotic elongation factor 2. The phosphorylation results from ...
Gutekunst Matthias - - 2013
Testicular germ cell tumors (TGCT) are considered a paradigm of chemosensitive tumors. Embryonal carcinoma (EC) cells represent the pluripotent entity of TGCT and are characterized by expression of Oct-4, a key regulator of pluripotency and a determinant of their inherent hypersensitivity to Cisplatin. However, the mechanisms underlying this Oct-4-mediated sensitivity ...
Roman Ashley S - - 2013
Objective To determine if prophylactic cerclage improves pregnancy outcomes in women with twin pregnancies without a history of cervical insufficiency.Study Design Women with twin pregnancies who received outpatient preterm labor surveillance services between January 1990 and May 2004 for ≥1 day beginning at < 28.0 weeks' gestation were identified from a database. Patients with ...
Hoffmann Achim - - 2013
The fatty acid pattern of dietary lipids can be modified during rumen biohydrogenation (BH). The objective of the present study was to assess changes in the FA pattern of different oilseed products supplied either as crushed full fat oilseed or as free oil after in vitro incubation with buffered rumen ...
Niazi Amir A - - 2013
We have used molecular dynamics simulations to study the properties of three ionic liquid (IL)/water systems: 1-butyl-3-methyl\-imidazolium chloride ([bmim]Cl), 1-ethyl-3-methyl\-imidazolium acetate ([emim][Ac]) and 1,3-dimethyl\-imidazolium dimethylphosphate ([dmim][DMP]). We observe the transition of those mixtures from pure IL to aqueous solution by analyzing the changes in important bulk properties (density), structural and ...
Moore Linda W - - 2013
The actual dietary protein intake of adults without and with different stages of chronic kidney disease is not known. To evaluate this we performed cross-sectional analyses of 16,872 adults (20 years of age and older) participating in the National Health and Nutrition Examination Survey 2001-2008 who completed a dietary interview ...
Alioglu Bulent - - 2013
Objective: The aim of this study is to evaluate how fish oil supplementation in children affects platelet function tests in vitro. Materials and Methods: The study included 62 children (20 healthy children without any medications and 42 healthy children who volunteered to take fish oil supplementation) aged between 2 and ...
Gholap Shivajirao L - - 2013
Starting from an easily available pyridinol derivative, a route to penta(2-thienyl)pyridine and related symmetrical compounds is reported. Key reactions are activation of the pyridine core and metal-catalyzed couplings proving the efficacy of these methods even in sterically highly encumbered systems. UV/vis and fluorescence spectra as well as first cyclovoltametric measurements ...
Shih Shou-Chuan - - 2013
BACKGROUND AND GOAL: Symptomatic gallstone disease (SGSD) induced several inflammatory responses and affected extrahepatic bile ducts. Although the pathology and environmental risk factors of gallstone disease (GSD) are well documented, immune or inflammatory responses in SGSD development are still inconclusive. Interleukin 18 (IL18) is a proinflammatory cytokine that plays an ...
Williges Christian - - 2013
Nano- patterning with block-copolymers finds many applications ranging from optics to bioscience. Many of these uses demand highly ordered patterns that are difficult to obtain due to environmental influences during the fabrication. Here we demonstrate that ultrasonication improves the hexagonal order of artificially disturbed micellar nano patterns.
Leonardi Darío - - 2013
This work investigated the feasibility of developing benznidazole (BZL) tablets, allowing fast, reproducible, and complete drug dissolution, by compressing BZL-Polyethylene Glycol (PEG) 6000 physical mixtures (PMs) and solid dispersions (SDs). SDs were prepared by the solvent evaporation method at different drug:polymer ratios (w/w). BZL-PEG 6000 formulations were characterized by X-ray ...
Guidotti Serena - - 2013
The molecular mechanisms underlying spermine osteo-inductive activity on human adipose-derived stem cells (ASC) grown in 3 dimensional (3D) cultures were investigated. Spermine belongs to the polyamine family, naturally occurring, positively-charged polycations able to control several cellular processes. Spermine was used at a concentration close to that found in platelet-rich plasma ...
Shepard Allan R - - 2013
Glaucoma and age-related macular degeneration are ocular diseases targeted clinically by anecortave acetate (AA). AA and its deacetylated metabolite, anecortave desacetate (AdesA), are intraocular pressure (IOP)-lowering and angiostatic cortisenes devoid of glucocorticoid activity but with an unknown mechanism of action. We used a methotrexate-anchored yeast three-hybrid (Y3H) technology to search ...
van Kruchten Roger - - 2013
Scott syndrome, a bleeding disorder caused by defective phospholipid scrambling, has been associated with mutations in the TMEM16F gene. The role of TMEM16F in apoptosis- or agonist-induced phosphatidylserine (PS) exposure was studied in platelets from a Scott syndrome patient and control subjects. Whereas stimulation of control platelets with the BH3-mimetic ...
Salcedo Suzana Pinto - - 2013
Brucellae replicate in a vacuole derived from the endoplasmic reticulum (ER) in epithelial cells, macrophages and dendritic cells. In animals, trophoblasts are also key cellular targets where brucellae efficiently replicate, in association with the ER. Therefore, we investigated the ability of Brucella spp. to infect human trophoblasts using both immortalized ...
Dudas Kerstin - - 2013
Background:Many patients with chronic heart failure (CHF) experience uncertainty regarding the treatment and characteristics of their illness. Person-centred care (PCC) emphasizes patient involvement in care. We have previously shown that PCC improved outcomes such as length of hospital stay and activities of daily living in patients with CHF. The impact ...
Sharma Dinesh - - 2013
Conjoined twins have been the subject of myth and legend since antiquity because of the rarity and peculiarity of their juxtaposition. Fortunately, modern medical technology and concurrent advancements in surgical techniques provide an opportunity for successful separation and hope of a normal independent existence for these unique children. Antenatal sonography ...
Wendremaire Maeva - - 2013
Reorganization of myometrial extracellular matrix (ECM) is essential for the uterus to achieve powerful synchronous contractions during labor. Remodeling of the ECM has been implicated in membrane rupture and cervical ripening. Since maternal obesity is associated both with delivery disorders and elevated circulating leptin level, this study aimed to assess ...
Inagaki S - - 2013
Transposable elements (TEs) are epigenetically silenced with extensive DNA methylation. The silent epigenetic marks should, however, be excluded from active genes. By genetic approaches, we study mechanisms to remove the heterochromatin marks from transcribed genes. Based on our observations on control of TE transcription, we propose a possible trigger for ...
Noda Hiroyuki - - 2013
Faults in Earth's crust accommodate slow relative motion between tectonic plates through either similarly slow slip or fast, seismic-wave-producing rupture events perceived as earthquakes. These types of behaviour are often assumed to be separated in space and to occur on two different types of fault segment: one with stable, rate-strengthening ...
Burns David J - - 2013
A concise synthesis of the AB rings of samaderine C (12 steps, 8 isolation steps, 7.8% overall yield), a quassinoid with antifeedant and insecticidal activity, is described. The development of the first general approach to the trans-1,2-diol A-ring motif in samaderine C and other quassinoids is a key feature. The ...
Sato Akira - - 2013
During neural development, even in seemingly homogeneous cell populations, individual neurons acquire diverse morphology and behavior, and even adjacent neurons can establish synaptic connections with distinct targets. Although diversity among individual neurons is essential for a functional nervous system, the underlying molecular mechanism of establishing heterogeneity in a population of ...
Karlsson Gunilla Paulson - - 2013
Background: Anorexia nervosa (AN) is a serious psychiatric disorder with high mortality rates a poor outcome and no empirically supported treatment of choice for adults. Weight increase is essential for recovery from AN why research exploring important contributors is crucial. Aims: The current study examined the importance of motivation to ...
García-Arévalo Carmen - - 2013
This study investigates both the physicochemical properties and immunogenicity of a genetically engineered elastin-like block co-recombinamer (ELbcR) containing a major membrane protein sequence from Mycobacterium tuberculosis. The recombinant production of this ELbcR allows the production of large quantities of safe, antigenic particle-based constructs that directly and reversibly self-assemble into highly ...
Kellermann Stefanie Julia - - 2013
Short fuses: RNA can be detected sequence specifically by using two RNA binding proteins fused to short strands derived from GFP and an additional large GFP fragment. The tetramolecular system has a high signal-to-noise ratio, discriminates between closely related RNA, and works in RNA preparations as well as E. coli ...
Brabcová Jana - - 2013
A serine protease was isolated from midguts of the bumblebee male Bombus terrestris by a combination of precipitation procedures with column chromatography. The purified enzyme exhibited two bands with molecular masses of 25 and 26 kDa as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis. These bands showed a proteolytic ...
Lee Chong-Yong - - 2013
Nanoporous materials: High-aspect-ratio, ordered porous Co(3) O(4) layers were formed by self-organizing anodization of a cobalt substrate and subsequent annealing. The key for successful formation of such layers is to sufficiently suppress competing oxygen evolution during anodization. The aligned Co(3) O(4) channel layers behave as a highly efficient water oxidation ...
De Jong Jonas S S G - - 2013
Early ischemic ventricular fibrillation (VF) in the setting of an acute myocardial infarction (AMI) due to thrombotic coronary occlusion remains a major health problem. Several animal studies have shown that platelet-dense granule contents released during thrombus formation can induce arrhythmias. We hypothesize that the platelet release reaction is involved in ...
Sazama Petr - - 2013
Shape-selective reactions: Highly selective catalysts are obtained by alkaline and subsequent acid leaching of conventionally prepared zeolites. Active sites that are located in the shape-selective environment of micropores and accessible through mesopores provide high selectivity and activity in acid-catalyzed reactions.
Arieli Sharon - - 2013
OBJECTIVE: To study value change, this research presents an intervention with multiple exercises, designed to instigate change through both effortful and automatic routes. Aiming to increase the importance attributed to benevolence values, which reflect the motivation to help and care for others, the intervention combines three mechanisms for value change ...
Intzes Stefanos - - 2013
Pulmonary diseases form major sources of morbidity and mortality in children with sickle cell disease (SCD). The objective of the study was to determine the prevalence of lung function abnormalities and asthma and their association with acute chest syndrome (ACS) in children with SCD. This was a cross-sectional retrospective study ...
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