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Results 401 - 450 of 3240
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Ciarrocca Manuela - - 2013
The aim of this study was to evaluate the usefulness and specificity of urinary 1-hydroxypyrene (1-OHPu) as a biomarker of the exposure from urban pollution to polycyclic aromatic hydrocarbons (PAHs) among outdoor workers in a meta-analysis. Our meta-analysis was performed according to standard methods, and the results show that the ...
Balanescu Andra - - 2013
Rheumatoid arthritis (RA) is a chronic, systemic, progressive inflammatory disease that, if left untreated, can lead to irreversible joint damage and serious disability. In Central and Eastern Europe, RA treatment varies widely, partly due to economic factors, restrictive treatment guidelines, and access to practicing rheumatologists. The recent treatment paradigm shift ...
Lev Bogdan - - 2013
We have studied Li(+)/Na(+)/K(+) selectivity of the bacterial aspartate transporter Glt(Ph) using all-atom molecular dynamics (MD) and free energy simulations (FES) to evaluate the role of different factors that control ion preferences of the binding sites identified in the crystallographic structure. The role of the bound ions in stabilizing the ...
Zhang Xiao-Yang - - 2013
Somatic-nonsomatic integration is critical for generation and execution of an appropriate and coordinated behavioral response to changes in internal and external environments. However, the underlying neural substrates and mechanisms are still enigmatic. Intriguingly, the central histaminergic and orexinergic systems originating from the hypothalamus, a high autonomic regulatory center, innervate almost ...
Gil V - - 2013
BACKGROUND AND PURPOSE: Hydrogen sulphide (H(2) S) is an endogenous gaseous signalling molecule with putative functions in gastrointestinal motility regulation. Characterization of H(2) S effects on colonic motility is crucial to establish its potential use as therapeutic agent in the treatment of colonic disorders. EXPERIMENTAL APPROACH: H(2) S effects on ...
Fowler John - - 2013
This series of articles is designed to help you advance your nursing practice; it begins by exploring the motivation to advance your practice and the differences between specialist and advanced practice.
Piazza Gregory - - 2013
The US Surgeon General estimates that 100,000 to 180,000 deaths occur annually from acute pulmonary embolism (PE) in the United States. The case of Ms A, a 60-year-old woman with acute PE and right ventricular dysfunction (submassive PE), illustrates the clinical challenge of identifying this high-risk patient population and determining ...
Molina A - - 2013
A key concept underpinning electrochemical science is that of the diffusion layer - the zone of depletion around an electrode accompanying electrolysis. The size of this zone can be found either from the simulated or measured concentration profiles (yielding the 'true' diffusion layer thickness) or, in the case of the ...
Hong Yong Sang - - 2013
The goal of the present study was to compare the combination of cetuximab and irinotecan to the combination of oxaliplatin and fluoropyrimidines as second-line chemotherapy in patients with irinotecan-refractory and oxaliplatin-naïve metastatic colorectal cancer (mCRC) harbouring wild-type KRAS. The study included 120 patients with mCRC who had progressed after irinotecan-containing ...
Buglione Antonio - - 2013
The aim of this study was to: (1) determine directly the energy cost of shuttle running (C (Sh)) and (2) compare it to the values indirectly estimated from kinematic data. C (Sh) over distances of ≈10 or ≈20 m was determined on 65 subjects (group 1) from gas exchange measurements over ...
Kim Yong Seung - - 2013
A single-layer graphene is synthesized on Cu foil in the absence of H(2) flow by plasma enhanced chemical vapor deposition (PECVD). In lieu of an explicit H(2) flow, hydrogen species are produced during the methane decomposition process into their active species (CH(x<4)), assisted with the plasma. Notably, the early stage ...
Leite Andreia - - 2013
In the present work we describe the structure and the spectroscopic characterization of a spirocyclic derivative of a rhodamine B ligand whose properties allow discrimination of light-up effects induced by metal ion chelation and variation of pH. Distinction of the two effects is important for the use of this type ...
Li Hua - - 2013
The supportive and negative evidence for the stress gradient hypothesis (SGH) led to an ongoing debate among ecologists and called for new empirical and theoretical work. In this study, we took various biological soil crust (BSCs) samples along a spatial gradient with four environmental stress levels to examine the fitness ...
Mlosek Robert K - - 2013
INTRODUCTION: The appropriate skin hydration level enables its normal function and healthy appearance. PURPOSE: The purpose of present research was to assess the applicability of high frequency ultrasound (HFU) to the monitoring of skin moisturization treatments. MATERIAL AND METHODS: The study sample encompassed 27 women, aged 20-67 y.o. (mean age ...
Ryu Min Ju - - 2013
This study investigated the mechanisms underlying the cytotoxicity of the green algae Ulva fasciata Delile. U. fasciata extract (UFE) inhibited the growth of HCT 116 human colon cancer cells by 50% at a concentration of 200 μg/ml. In addition, UFE stimulated the production of intracellular reactive oxygen species, an effect that ...
Rahman Shakibur - - 2013
BACKGROUND: Worldwide studies on lung adenocarcinoma have demonstrated a genetic divergence of the epidermal growth factor receptor (EGFR) pathway according to ethnicity, such as higher frequency of activated EGFR mutations among East Asian patients. However, such information is still lacking in some developing countries. METHODS: We investigated the frequency of ...
Xue Baoming - - 2013
Concentrations, distributions and sources of PAHs were investigated in surface sediments from Lijiang River, South China. The total PAHs concentrations ranged from 160  to 602 ng g(-1) dry weight.The total PAHs concentrations from different area descended in the order: middle reach > upper reach > down reach. Based on the PAHs indicators ...
Andree K B - - 2013
Inspections by customs agents at Barcelona airport discovered 420 kg of contraband glass eels prepared for shipment to Hong Kong. After confiscation of these animals by police, they were transported to holding facilities to be maintained until after a judicial hearing. Upon arrival, they were separated into two groups and held ...
Gamaldo Charlene E - - 2013
Amongst HIV+ individuals, sleep complaints have been recognized as common and debilitating; but have rarely been formally assessed or compared to controls using validated sleep tools. In this study we conducted structured interview for sleep disorders, polysomnography, 2-week home (ambulatory) monitoring and validated sleep/functional questionnaires. 56 % (14/25) of HIV+ participants ...
Brown S A - - 2013
Context. Envenomations during pregnancy pose all the problems of envenomation in the nonpregnant state with additional complexity related to maternal physiologic changes, medication use during pregnancy, and the well-being of the fetus. Objective. We review the obstetric literature and management options available to prevent maternal morbidity and mortality while limiting ...
Galldiks Norbert - - 2013
To evaluate in a single center retrospectively the efficacy and tolerability of a weekly regimen, which alternates temozolomide (TMZ) in patients with recurrent or progressive high-grade glioma (HGG). From January 2005 until June 2011, 54 patients with recurrent or progressive HGG were treated with TMZ 150 mg/m²/day on days 1-7 and ...
Wilson Peter M - - 2013
Despite compelling preclinical data in colorectal cancer (CRC), the efficacy of HDACIs has been disappointing in the clinic. The goal of this study was to evaluate the effectiveness of vorinostat and panobinostat in a dose- and exposure-dependent manner in order to better understand the dynamics of drug action and antitumor ...
Hammad Ayman - - 2013
BACKGROUND: About 10-20 % of children with idiopathic nephrotic syndrome (NS) are steroid-resistant (SR). Low expression of glucocorticoid receptors (GRs) has been associated with poor response to steroids in a variety of autoimmune diseases. This study was done to assess the expression of cytoplasmic GRs for CD3 and CD14 in ...
Mohammed Magdy M D - - 2013
As part of our ongoing collaborative effort to discover potential anti-HIV-1 agents from plants, the CH(2)Cl(2) extract of Calocephalus brownii F. Muell. was phytochemically investigated, which resulted in the isolation of two sesquiterpene lactones of the cis-fused guaianolides type, one new identified as 1α-hydroxy-3βH-3α,4α-epoxy-4,10-dimethyl-5αH,7αH,8βH,10αH-guai-11(13)-ene-7,8-olide (1) and one known identified 1αH-4α-hydroxy-4,10-dimethyl-5αH,7αH,8βH,10αH-guai-11(13)-ene-7,8-olide ...
Velmurugan Sathya - - 2013
In the rat hypothalamus, fasting attenuates the expression of oxytocin and this can be reversed by exogenous leptin administration. Here, we studied the effects of systemically administered leptin on the electrical activity of magnocellular neurones in the supraoptic nucleus of urethane-anaesthetized rats. In virgin female rats, systemic leptin significantly excited ...
Herrera Mercedes - - 2013
Tumor epithelial cells within a tumor coexist with a complex microenvironment in which a variety of interactions between its various components determine the behavior of the primary tumors. Cancer-associated fibroblasts (CAFs) and M2 macrophages, characterized by a high expression of different markers, including α-SMA, FSP1 and FAP, or CD163 and ...
Venditti Alessandro - - 2013
Endemic Sideritis italica (MILL.) GREUTER et BURTER (Lamiaceae) occurs mainly in Southern Italy and Sicily and has previously only been studied for the essential oil composition. In this paper, we complete the phytochemical study of a sample of S. italica, previously analysed for its volatile constituents, occurring in the Appennino ...
Petkov Boyan - - 2013
Variations in total ozone column and sun exposures able to cause erythema and damage the DNA molecules were observed by the narrow-band filter radiometer UV-RAD in Bologna, Italy from 2005 to 2010. The ozone columns determined from the UV-RAD measurements were found to be close to those provided by the ...
Dovgopoly Alexander - - 2013
Individuals with autism spectrum disorder (ASD) show atypical patterns of learning and generalization. We explored the possible impacts of autism-related neural abnormalities on perceptual category learning using a neural network model of visual cortical processing. When applied to experiments in which children or adults were trained to classify complex two-dimensional ...
Rayburn Andrew P - - 2013
Although plant spatial patterns strongly influence community-structuring processes, few empirical studies have addressed pattern effects on perennial community dynamics. We tested the effects of community- and neighborhood-scale patterns in experimental semi-arid grassland communities comprising the stronger competitor crested wheatgrass (Agropyron cristatum) and the weaker competitor Snake River wheatgrass (Elymus wawawaiensis). ...
Carneiro Paula - - 2013
The present study analyzed the retrieval dynamics of false recall, using an externalized free-recall task after participants studied Deese/Roediger-McDermott lists with high- and low-identifiable critical words. In Experiment 1, the memory test required participants to write down the words they remembered as having been presented in each list (recall output) ...
Xu Yun-Hua - - 2013
The development of lung cancer is significantly associated with genetic susceptibility. Findings from previous individual studies regarding the effect of X-ray repair cross-complementing group 3 Thr241Met (XRCC3 Thr241Met) polymorphism on lung cancer risk remained conflicting and inconclusive. Thus, a meta-analysis of previous relevant studies was performed to estimate this effect ...
Pulis Eric E - - 2013
Species of the Haploporidae Nicoll, 1914 with elaborate muscularisation of the oral sucker belong in three trematode genera, including three new species and a new genus from the intestine of fishes in Australian waters. Spiritestis Nagaty, 1948 is resurrected and S. herveyensis n. sp. is described from the mullet Moolgarda ...
Sudar Martina - - 2013
Cell disruption process of dry baker's yeast was studied in this work to obtain maximum activity of alcohol dehydrogenase (ADH). Disruption by ultrasonication, glass beads, and combination of these two methods was compared. A 1.8-fold increase of ADH activity can be achieved by combining glass beads with ultrasonication in comparison ...
Foster Paul S - - 2013
Abstract Some evidence exists supporting a relationship between spreading activation in semantic/lexical memory networks and episodic memory. However, the results have been mixed and there have been no investigations examining whether a relationship exists between variability in spreading activation and episodic memory. Hence, we sought to investigate these potential relationships. ...
Levine Stephen Z - - 2013
PURPOSE: The current study aims to examine the potential use of the seven-item Center for Epidemiologic Studies Depression Scale (CES-D) short form (CES-D-SF). METHODS: Data were examined from the National Longitudinal Survey of Youth 1979. Participants responded to the 20-item CES-D (n = 8,858) in 1992, and to the 7-item CES-D-SF in ...
Rees M L - - 2013
Previous studies from our laboratory have shown positive benefits of linoleic acid (LA) feeding for attenuation of rat heart failure (HF). However, another research group concluded LA feeding was detrimental to cardiac function, using the American Institute of Nutrition 76A (AIN) diet as a background diet for the experimental animals ...
Uchida Mitsuo - - 2013
The effects of change of residence on pollinosis symptoms remain unclear. We investigated the effects of geographical change of residence on pollinosis symptoms among university freshmen. All freshmen (n = 2142) entering Shinshu University in 2011 completed self-administered questionnaires. Associations between history of pollinosis and environmental factors were assessed. Subjects were classified ...
Khan Muhammad Asad - - 2013
BACKGROUND: Although the mortality from bariatric surgery is low, perioperative determinants of morbidity and mortality in the bariatric surgery population to date have not been fully defined. This study aimed to evaluate the factors capable of predicting perioperative mortality based on preoperative characteristics with a national patient sample. METHODS: From ...
Smets Jorien - - 2013
According to the CaRFAX model, rumination is one of the key underlying mechanisms of overgeneral autobiographical memory (OGM). The association between rumination and OGM is well established in clinical populations, but this relationship is not robust in nonclinical samples. A series of null findings is reported in the current paper. ...
Husain Fohad Mabood - - 2013
Inhibition of quorum sensing (QS)-regulated virulence factors including biofilm is a recognized anti-pathogenic drug target. The search for safe and effective anti-QS agents is expected to be useful to combat diseases caused by multidrug-resistant bacteria. In this study, effect of a commonly used antibiotic, doxycycline on QS was evaluated using ...
Pan L A - - 2013
BACKGROUND: Neural substrates of emotion dysregulation in adolescent suicide attempters remain unexamined. Method We used functional magnetic resonance imaging to measure neural activity to neutral, mild or intense (i.e. 0%, 50% or 100% intensity) emotion face morphs in two separate emotion-processing runs (angry and happy) in three adolescent groups: (1) ...
Ward Lesley - - 2013
OBJECTIVES: Musculoskeletal conditions (MSCs) are the leading cause of disability and chronic pain in the developed world, impacting both functional ability and psychosocial health. The current review investigates the effectiveness of yoga on primary outcomes of functional ability, pain and psychosocial outcomes across a range of MSCs. METHODS: A comprehensive ...
Fanelli Fabrizio - - 2013
PURPOSE: To describe the 1-year results of drug-eluting nitinol stent placement in the femoropopliteal artery of diabetic and nondiabetic patients. MATERIALS AND METHODS: All patients enrolled in this prospective, multicenter study underwent paclitaxel-eluting stent placement for de novo or restenotic lesions of the superficial femoral and/or popliteal artery. Baseline and ...
Zhang Wei - - 2013
The purpose of this study was to examine the variations in the microbial community structure of soil actinomycetes in fields with continuous cropping of cotton in Xinjiang Autonomous Region, China. Soil samples were collected from four depths in fields with 7-year continuous cotton cropping. The community structure of soil actinomycetes ...
Pittaluga Monica - - 2013
Abstract Aging is characterized by an impaired capacity to maintain the redox balance both in physiological and pathological situations associated with an increased production of reactive oxygen species. Since the extent of this phenomenon may be influenced by an antioxidants rich diet, we investigated the effect of supplementation with fresh ...
Kamiya Naoto - - 2013
BACKGROUND: The aim of this study was to retrospectively investigate clinical outcomes by relative dose and dose intensity of docetaxel (DOC) as chemotherapy for Japanese patients with castration-resistant prostate cancer (CRPC). METHODS: A total of 145 CRPC patients who received more than 4 courses of DOC chemotherapy at 14 hospitals ...
Bell Reginald C W - - 2013
BACKGROUND: Hiatal repair failure is the nemesis of laparoscopic paraesophageal hernia repair as well as the major cause of failure of primary fundoplication and reoperation on the hiatus. Biologic prosthetics offer the promise of reinforcing the repair without risks associated with permanent prosthetics. DESIGN: Retrospective evaluation of safety and relative ...
Halfon Philippe - - 2013
A new genotyping-based DNA assay (Digene LQ(®)) was developed recently. The primary aim was to assess the distribution of HPV types using this new assay in atypical squamous cells of undeterminate significance (ASCUS). The secondary aim was to correlate the HPV types with the severity of the disease. The study ...
Kusano Toru - - 2013
BACKGROUND: Whether gastrectomy with D2 lymphadenectomy improves survival of patients with advanced gastric cancer (AGC) remains controversial. Few studies have described the pathological features of AGC with metastatic suprapancreatic lymph nodes (LN), which are the target of D2 lymphadenectomy. This study therefore aims to clarify the prognosis and clinical pathological ...
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