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Results 351 - 400 of 3241
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Krausz Reinhardt Michael - - 2013
OBJECTIVE: To determine the standardized rates of mental disorder, health service use and barriers to care in a representatively diverse sample of homeless adults in three different sized urban centers in British Columbia, Canada. METHOD: Five hundred homeless adults from Vancouver, Victoria and Prince George were recruited. The MINI-International Neuropsychiatric ...
Meins Elizabeth - - 2013
Relations between mothers' tendency to comment appropriately on their 8-month-olds' internal states (mind-mindedness) and children's behavioral difficulties (Strengths and Difficulties Questionnaire) at ages 44 and 61 months were investigated in a socially diverse sample (N = 171, 88 boys). Controlling for maternal depressive symptoms, perceived social support, sensitivity, child language ability, and child ...
Watanabe Jun - - 2013
MNSFβ is a ubiquitously expressed member of the ubiquitin-like family that has been involved in various biological functions. Previous studies have demonstrated that MNSFβ covalently binds to intracellular pro-apoptotic protein Bcl-G and regulates the ERK-MAPK cascade in mouse macrophage cell line, Raw264.7. In this study, we demonstrate that MNSFβ promotes ...
Al-Kasspooles Mazin F - - 2013
The present studies were carried out to examine the efficacy of a nanoparticulate formulation of SN38, the potent topoisomerase I inhibitor and active metabolite of irinotecan. Metabolism of irinotecan to SN38 is inefficient and subject to considerable patient-to-patient variability. One approach to more controlled administration of the anticancer agent is ...
Poggio Claudio - - 2013
AIM: The purposes of this study were to evaluate the effect of surface pretreatment with phosphoric acid on the enamel bond strength of four-one-step self-etch adhesives with different pH values. MATERIAL AND METHODS: One hundred bovine permanent mandibular incisors were used. The materials used in this study included four-one-step self-etch ...
Schaeffner Bjoern C - - 2013
A new genus of trypanorhynch cestodes, Pristiorhynchus n. g. (Otobothrioidea: Otobothriidae), is described from two species of modern sawfishes (Pristidae) from off northern Australia. Pristiorhynchus palmi n. g., n. sp. is characterised by an acraspedote scolex with two bothria, paired bothrial pits on the posterior margins of each bothrium, the ...
Roy Souvik - - 2013
In the present study, we aimed to investigate the protective effect of ferulic acid at different doses (50 mg/kg alternative day and 50 mg/kg daily) on diabetic rats and to explore the interrelationship between oxidative stress and cytokines correlates with apoptotic events in pancreatic tissue. Male Wistar rats were rendered diabetic by ...
Fernando A B P - - 2013
RATIONALE: Safety signals providing relief are hypothesised to possess conditioned reinforcing properties, supporting the acquisition of a new response (AnR) as seen with appetitive stimuli. Such responding should also be sensitive to the rate-increasing effects of d-amphetamine and to the anxiolytics 8-OH-DPAT and diazepam. OBJECTIVES: This study tests whether safety ...
Becker Felicitas - - 2013
Recent studies reported mutations in the gene encoding the proline-rich transmembrane protein 2 (PRRT2) to be causative for paroxysmal kinesigenic dyskinesia (PKD), PKD combined with infantile seizures (ICCA), and benign familial infantile seizures (BFIS). PRRT2 is a presynaptic protein which seems to play an important role in exocytosis and neurotransmitter ...
Bertero Alice - - 2013
Abstract Dendrimers are branched polymers with spherical morphology. Their tunable chemistry and surface modification make them valuable nanomaterials for biomedical applications. In view of possible dendrimer uses as brain-aimed nanocarriers we studied amine- and lipid-functionalized (G4) polyamidoamine (PAMAM) biocompatibility with cell population forming the Blood Brain Barrier (BBB). Both PAMAM ...
Noda Yoko - - 2013
ABSTRACT: BACKGROUND: Postprandial hyperlipidemia impairs endothelial function and participates in the development of atherosclerosis. We investigated the postprandial effects of a dipeptidyl peptidase IV inhibitor, alogliptin, on endothelial dysfunction and the lipid profile. METHODS: A randomized cross-over trial design in 10 healthy volunteers (8 males and 2 females, 35 +/- ...
Sadava Emmanuel E - - 2013
BACKGROUND: A variety of permanent and absorbable tacks are available for mesh fixation during laparoscopic hernia repairs. Although manufacturers recommend deploying tacks perpendicular to the tissue, achieving this can sometimes be challenging. This study aimed to analyze comparatively the effects of angled deployment among commonly used tacks. METHODS: A piece ...
Röpke Albrecht - - 2013
The steroidogenic factor 1 (SF1) protein, encoded by the NR5A1 gene, plays a central role in gonadal development and steroidogenesis. Mutations in NR5A1 were first described in patients with primary adrenal insufficiency and 46,XY disorders of sexual development and later also in men with hypospadias, bilateral anorchia and micropenis and ...
Li Li - - 2013
Tuber yield, starch content, starch yield and chip color are complex traits that are important for industrial uses and food processing of potato. Chip color depends on the quantity of reducing sugars glucose and fructose in the tubers, which are generated by starch degradation. Reducing sugars accumulate when tubers are ...
Liu Xiang-Yin - - 2013
PURPOSE: To explore the prevalence and clinical features, especially the reproductive function, of 45,X mosaicism patients in northeast China. METHODS: GTG-banding was performed on a series of 2,250 patients from our genetic counseling clinic. Each of these patients underwent a physical examination and was interviewed about their medical history and ...
Jackson D - - 2013
The sea lice population structure, prevalence and intensity of Lepeophtheirus salmonis have been studied over a period extending from 2004 to 2011. Infestation data were collected from the interceptor drift net fishery from 2004 until it was closed in 2006. From 2010, data were collected from the inshore draft net ...
Marie-Ève Roy-Lacroix - - 2013
Objective: To determine the impact of the duration of fetal exposure to inflammation on the neurological outcome of pups. Method: Time-pregnant Sprague-Dawley rats (n=32) received intraperitoneal injection of lipopolysaccharides (LPS; 500µg/kg), or an equivalent volume of vehicle 3h, 6h, 12h and 24h before C-section. Maternal serum and amniotic fluid were ...
Hwang Sung Ho - - 2013
OBJECTIVES: To compare tumour enhancement patterns measured using dynamic contrast-enhanced (DCE)-CT with tumour metabolism measured using positron emission tomography (PET)-CT in patients with non-small cell lung cancer (NSCLC) and stable disease after chemotherapy or chemoradiotherapy. METHODS: After treatment, 75 NSCLC tumours in 65 patients who had stable disease on DCE-CT ...
Wang Jian - - 2013
The aim of the present study was to clarify the expression of fibroblast growth factor-inducible 14 (Fn14), a type I transmembrane protein, in breast carcinoma and its correlation with clinicopathological features.We examined the expression of Fn14 in normal breast epithelial cells as well as in breast carcinoma cells, and in ...
Nayak Purnendu K - - 2013
The wide diversity of room-temperature ionic liquids (ILs) presents opportunities for studying, and controlling, polymer phase behavior. We have examined the phase behavior of poly(N-isopropyl acrylamide) (PNIPAM) in imidazolium ILs and their mixtures with water. We find there is a strong influence of the IL anion; specifically, the tetrafluoroborate anion ...
Tinsley R C - - 2013
Exceptional occurrences have fundamental interest in evolution relevant to understanding adaptations and origins. Monogeneans primarily infect aquatic lower vertebrates, i.e. fish, amphibians and chelonian reptiles, but there is a single instance of colonisation of a mammal: Oculotrema hippopotami Stunkard, 1924 infecting the eye of Hippopotamus amphibius Linnaeus. Its combination of ...
Shan Aixian - - 2013
The magnetism of undoped ZnS nanotetrapods, synthesized by a solvothermal method, has been investigated by magnetization measurements and first principle numerical calculations. The background magnetic impurity concentrations of Fe, Co and Ni were determined at ppm level by inductively coupled plasma mass spectrometry (ICP-MS). Hysteresis loops of weak ferromagnetism were ...
Yozu Masato - - 2013
Muir-Torre syndrome is a variant of Lynch syndrome, characterised by sebaceous neoplasia and/or keratoacanthomas associated with visceral malignancies. Muir-Torre syndrome is caused by germline mutations of one of the mismatch repair genes, frequently MSH2 and less frequently MLH1 and MSH6. Visceral malignancies associated with Muir-Torre syndrome and Lynch syndrome include ...
Mills S D H - - 2013
A large body of research confirms that food advertising affects the food preferences and behaviour of children. The impact of food advertising on adults is less clear. We conducted a systematic review exploring the effects of advertising of food and non-alcoholic drinks (referred to as 'food' throughout) on food-related behaviour, ...
Oda─č Ozen - - 2013
This contribution examines the emotional engagement of men and women when reading narrative texts, aiming to see under which textual conditions men and women turn out to be different from or similar to each other in what they think and feel during reception. As part of an experimental mixed-methods study, ...
Chen Gang - - 2013
BACKGROUND: Genetic determinations are important in type 2 diabetes (T2D) pathology. We investigated associations between genetic variants of 17 diabetes-related genes/loci, T2D and diabetic complications in Chinese She subjects. METHODS: A comprehensive gene-based association study was conducted using 17 single nucleotide polymorphisms (SNPs) in Chinese She subjects with normal glucose ...
Zhang Tianshui - - 2013
A new synthesis of substituted 1H-indazoles and 1H-pyrazoles from arylhydrazones via FeBr3/O2 mediated C-H activation/C-N bond formation reactions is reported. The corresponding 1, 3-diarylsubstituted indazoles and trisubstituted pyrazoles were obtained in moderate to excellent yields under mild conditions.
Thacker Philip - - 2013
This experiment determined the effects of including normal and low-phytate peas in diets fed to young broiler chickens on performance, phosphorus availability and bone strength. A total of 180, day-old, male broilers (Ross-308 line) were assigned to six treatments. The control was based on corn and soybean meal while two ...
Mohammadi-Sangcheshmeh Abdollah - - 2013
Adipose-derived stem cells are an attractive alternative as a source of stem cells that can easily be extracted from adipose tissue. Isolation, characterization, and multi-lineage differentiation of adipose-derived stem cells have been described for human and a number of other species. Here we aimed to isolate and characterize camel adipose-derived ...
Cheng Xin - - 2013
Objective: To construct a plasmid containing a urate oxidase and creatinine hydrolase fusion gene and transform the plasmid into Escherichia coli to decompose uric acid and creatinine. Methods: According to the GenBank data for the urate oxidase gene, specific primers were designed to amplify and remove the stop codon for ...
Su Z - - 2013
This study identified a novel phenomenon that dendritic cells (DCs) produced interleukin (IL)-33 via Toll-like receptor (TLR)-mediated innate pathway. Mouse bone marrow-derived DCs were treated with or without microbial pathogens or recombinant murine IL-33. IL-33 mRNA and protein were found to be expressed by DCs and largely induced by several ...
Armstrong David R - - 2013
Designed to extend the synthetically important alkali-metal diisopropylamide [N(i)Pr(2); DA] class of compounds, the first example of a hetero-alkali-metallic complex of DA has been prepared as a partial TMEDA solvate. Revealed by an X-ray crystallographic study, its structure exists as a discrete lithium-rich trinuclear Li(2)KN(3) heterocycle, with TMEDA only solvating ...
Buret Andre G - - 2013
Abstract Enterocyte turnover along with proper epithelial barrier function are crucial aspects of mucosal defense. Apoptosis is a highly regulated type of programmed cell death that allows for the homeostatic turnover of the epithelial layer. Recent studies have suggested that microbial modulation of enterocyte apoptosis can result in increased epithelial ...
Parks Daniel - - 2013
PURPOSE: Identifying drug-induced liver injury is a critical task in drug development and postapproval real-world care. Severe liver injury is identified by the liver chemistry threshold of alanine aminotransferase (ALT) >3× upper limit of normal (ULN) and bilirubin >2× ULN, termed Hy's law by the Food and Drug Administration. These ...
Lakshmanan Yamunadevi - - 2013
PURPOSE: To determine the association between stereoacuity and severity of glaucoma. METHODS: Stereoacuity was measured using the Titmus stereo test for 97 glaucoma subjects with visual acuity better than 0.3 logMAR (6/12, 20/40 Snellen) and reliable Humphrey visual fields (24-2 SITA standard). The severity of visual fields was graded with ...
Moran Kevin - - 2013
In high-income countries, death as a consequence of recreational jumping into water from height has not been well investigated partly because it traditionally has been a covert activity within youth culture. An observational study of video recordings posted on the YouTube web site was used to gather data on the ...
Glasper Alan - - 2013
Professor Alan Glasper outlines the findings of the RCN-sponsored Willis Commission report. Its recommendations include introducing more community placements for nursing students.
Kong Ling - - 2013
At pH 1.3-1.6, tungstate WO(4) (2-) , can be converted to hexatungstate W(6) O(19) (2-) , which can react with positively charged polymyxin B sulfate (PMB) to result in enhancement of resonance Rayleigh scattering (RRS) and resonance non-linear scattering, including second order scattering and frequency doubling scattering. Linear relationships can ...
Wang Wen - - 2013
As a therapeutic or chemo-preventative agent to various cancers, all-trans retinoic acid (atRA) has been reported to inhibit the growth, induce apoptosis or cause differentiation. It was found that atRA could protect hepatocellular carcinoma (HCC) cells against cell death induced by serum starvation in the present study. Furthermore, it was ...
Abbott Sharon A - - 2013
Female sex workers (FSWs) were recruited for a 4-month placebo vaginal gel trial in Nellore, India. Two experiments explored if prior knowledge of biomarkers for unprotected sex and insertion of gel applicators would yield more accurate self-reports. A third experiment compared self-reports of gel use and adherence levels between FSWs ...
Kondo Masatoshi - - 2013
Our purpose in this study was to evaluate the image quality of low-radiation-dose CT using hybrid iterative reconstruction (HIR), and to compare the results with those of filtered back projection (FBP) at routine doses. We measured the mean values and standard deviation of the CT numbers within and outside a ...
Dostalek Miroslav - - 2013
Development of monoclonal antibodies (mAbs) and their functional derivatives represents a growing segment of the development pipeline in the pharmaceutical industry. More than 25 mAbs and derivatives have been approved for a variety of therapeutic applications. In addition, around 500 mAbs and derivatives are currently in different stages of development. mAbs are ...
Kim Kyung Won - - 2013
Vascular disrupting agents (VDAs) are new class of anti-cancer drugs targeting pre-existing tumor vasculature which lead to tumor ischemia and necrosis. An innovative tubulin polymerization inhibitor, CKD-516, was recently developed as a VDA. We attempted to evaluate its tubulin destabilizing effect using immunofluorescence staining on human endothelial cells (HUVECs) and ...
Caltik Aysun - - 2013
BACKGROUND: Peritoneal dialysis (PD) is an effective and successful therapy for end-stage renal disease (ESRD). However, PD does not have a life-long effectiveness, and peritoneal membrane failure is commonly observed in long-term PD patients. We hypothesized that ultrasonography could be used to follow these patients. METHODS: We recruited two patient ...
Mandal S K - - 2013
This study reports the measurement of stability constants for the interaction of As (V and III) and Sb (V and III) with humic substances extracted from aquatic sediments of the Sundarban mangrove forest ecosystem. It was observed that As and Sb formed a slightly more stable association with fulvic acid ...
Prochazka Lubomir - - 2013
α-Tocopheryl succinate (α-TOS) is a promising anti-cancer agent due to its selectivity for cancer cells. It is important to understand whether long-term exposure of tumour cells to the agent will render them resistant to the treatment. Exposure of the non-small cell lung carcinoma H1299 cells to escalating doses of α-TOS ...
Jia Zhiguang - - 2013
The antibiotic vancomycin targets lipid II blocking cell wall synthesis in Gram-positive bacteria. Despite extensive study, questions remain regarding how it recognizes its primary ligand and what is the most biologically relevant form of vancomycin. In this work molecular dynamics simulation techniques have been used to examine the process of ...
Siegler Ilene C - - 2013
BACKGROUND: Marital status is associated with survival. PURPOSE: The aims of this study are to evaluate marital history and timing on mortality during midlife, test the role of pre-marital personality, and quantify the role of health risk behaviors. METHODS: Cox proportional hazard models were run with varying classifications of marital ...
McLeod Jordache - - 2013
OBJECTIVE: The aim of the current study was to examine the ability of a performance measurement scale, the Care Transitions Measure (CTM) adequately to assess the quality of care transitions among a complex population of older musculoskeletal (MSK) rehabilitation patients. METHODS: Fifteen older (aged 60+) patients with MSK disorders were ...
Levengood Jeffrey M - - 2013
Documenting long-term trends in mercury deposition and/or accumulation is important in setting regulatory benchmarks, modeling contaminant transfer and flux, measuring success of environmental controls, and even assigning responsibility for pollution. We conducted a study to compare mercury concentrations in small fishes from "high-mercury" and "low-mercury" regions of Illinois, as well ...
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