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Results 301 - 350 of 3245
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Ohno Yoshio - - 2013
BACKGROUND: Cytoreductive nephrectomy (CN) plays an important role in the multimodal treatment of metastatic renal cell carcinoma (RCC). However, certain patients experience rapid progression of the carcinoma following CN. This study aimed to investigate the value of neutrophil-to-lymphocyte ratio (NLR) in the selection of patients for CN. METHODS: Records corresponding ...
Qin Mei M Section on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, - - 2013
Dysregulated protein synthesis is thought to be a core phenotype of fragile X syndrome (FXS). In a mouse model (Fmr1 knockout (KO)) of FXS, rates of cerebral protein synthesis (rCPS) are increased in selective brain regions. We hypothesized that rCPS are also increased in FXS subjects. We measured rCPS with ...
Gasparrini Antonio - - 2013
ABSTRACT: BACKGROUND: The two-stage time series design represents a powerful analytical tool in environmentalepidemiology. Recently, models for both stages have been extended with the development ofdistributed lag non-linear models (DLNMs), a methodology for investigating simultaneouslynon-linear and lagged relationships, and multivariate meta-analysis, a methodology to pool estimatesof multi-parameter associations. However, the ...
Bertero Alice - - 2013
Abstract Dendrimers are branched polymers with spherical morphology. Their tunable chemistry and surface modification make them valuable nanomaterials for biomedical applications. In view of possible dendrimer uses as brain-aimed nanocarriers we studied amine- and lipid-functionalized (G4) polyamidoamine (PAMAM) biocompatibility with cell population forming the Blood Brain Barrier (BBB). Both PAMAM ...
Noda Yoko - - 2013
ABSTRACT: BACKGROUND: Postprandial hyperlipidemia impairs endothelial function and participates in the development of atherosclerosis. We investigated the postprandial effects of a dipeptidyl peptidase IV inhibitor, alogliptin, on endothelial dysfunction and the lipid profile. METHODS: A randomized cross-over trial design in 10 healthy volunteers (8 males and 2 females, 35 +/- ...
Sadava Emmanuel E - - 2013
BACKGROUND: A variety of permanent and absorbable tacks are available for mesh fixation during laparoscopic hernia repairs. Although manufacturers recommend deploying tacks perpendicular to the tissue, achieving this can sometimes be challenging. This study aimed to analyze comparatively the effects of angled deployment among commonly used tacks. METHODS: A piece ...
Röpke Albrecht A Institute of Human Genetics, University of Münster, Münster, - - 2013
The steroidogenic factor 1 (SF1) protein, encoded by the NR5A1 gene, plays a central role in gonadal development and steroidogenesis. Mutations in NR5A1 were first described in patients with primary adrenal insufficiency and 46,XY disorders of sexual development and later also in men with hypospadias, bilateral anorchia and micropenis and ...
Li Li - - 2013
Tuber yield, starch content, starch yield and chip color are complex traits that are important for industrial uses and food processing of potato. Chip color depends on the quantity of reducing sugars glucose and fructose in the tubers, which are generated by starch degradation. Reducing sugars accumulate when tubers are ...
Liu Xiang-Yin - - 2013
PURPOSE: To explore the prevalence and clinical features, especially the reproductive function, of 45,X mosaicism patients in northeast China. METHODS: GTG-banding was performed on a series of 2,250 patients from our genetic counseling clinic. Each of these patients underwent a physical examination and was interviewed about their medical history and ...
Jackson D - - 2013
The sea lice population structure, prevalence and intensity of Lepeophtheirus salmonis have been studied over a period extending from 2004 to 2011. Infestation data were collected from the interceptor drift net fishery from 2004 until it was closed in 2006. From 2010, data were collected from the inshore draft net ...
Marie-Ève Roy-Lacroix - - 2013
Objective: To determine the impact of the duration of fetal exposure to inflammation on the neurological outcome of pups. Method: Time-pregnant Sprague-Dawley rats (n=32) received intraperitoneal injection of lipopolysaccharides (LPS; 500µg/kg), or an equivalent volume of vehicle 3h, 6h, 12h and 24h before C-section. Maternal serum and amniotic fluid were ...
Hwang Sung Ho SH Department of Radiology and Research Institute of Radiological Science, Yonsei University Health System, Seoul 135-720, Republic of - - 2013
To compare tumour enhancement patterns measured using dynamic contrast-enhanced (DCE)-CT with tumour metabolism measured using positron emission tomography (PET)-CT in patients with non-small cell lung cancer (NSCLC) and stable disease after chemotherapy or chemoradiotherapy. After treatment, 75 NSCLC tumours in 65 patients who had stable disease on DCE-CT according to ...
Wang Jian - - 2013
The aim of the present study was to clarify the expression of fibroblast growth factor-inducible 14 (Fn14), a type I transmembrane protein, in breast carcinoma and its correlation with clinicopathological features.We examined the expression of Fn14 in normal breast epithelial cells as well as in breast carcinoma cells, and in ...
Nayak Purnendu K - - 2013
The wide diversity of room-temperature ionic liquids (ILs) presents opportunities for studying, and controlling, polymer phase behavior. We have examined the phase behavior of poly(N-isopropyl acrylamide) (PNIPAM) in imidazolium ILs and their mixtures with water. We find there is a strong influence of the IL anion; specifically, the tetrafluoroborate anion ...
Yoshida R - - 2013
A new rhizocephalan species of the genus Dipterosaccus Van Kampen & Boschma, 1925, is described from the host hermit crab Calcinus vachoni Forest on the coasts of mainland Japan and the Ryukyu Archipelago. Dipterosaccus shiinoi n. sp. differs from the previously described species, D. indicus Van Kampen & Boschma, 1925, ...
Tang Baokun - - 2013
Bioethanol is considered a potential liquid fuel that can be produced from biomass by fermentation and distillation. Although most of the water is removed by distillation, the purity of ethanol is limited to 95-96 % due to the formation of a low-boiling point, water-ethanol azeotrope. To improve the use of ethanol ...
Khashab Mouen - - 2013
BACKGROUND AND AIMS: Endoscopic placement of enteral self-expandable metallic stents is an alternative to surgical gastrojejunostomy (GJ) for palliation of malignant gastric outlet obstruction (GOO). Factors associated with clinical outcomes are not known. The aims of this study are to compare the overall complication rate and effectiveness (duration of oral ...
Leow J J - - 2013
Obturator hernia is a rare surgical condition, with about 800 cases being reported in the literature. It can cause significant morbidity and mortality, especially in the elderly age group. Delayed treatment is associated with high rates of strangulation (25-100 %). The mainstay of management for obturator hernia has been surgical. Non-operative ...
Tripathi Pankaj - - 2013
Abstract The present study investigated the protective effects of Syzygium cumini extract (SCE; 100 and 200 mg/kg) against genotoxicity and oxidative stress (OS) induced by cyclophosphamide (CP) in mice. Animals were received 14 days pretreatment (oral) of SCE, followed by induction of genotoxicity by CP (40 mg/kg), 24 hours before sacrifice. Mice ...
Ozturan Orhan - - 2013
Saddle nose deformity presents a significant challenge to surgeons. The reconstruction of a saddle nose requires structural addition to the nasal dorsum and tip. Costal cartilage grafts have been utilized for fixing severe saddle nose deformity, but costal cartilage is notorious for early and/or late warping. In addition to well-known ...
Karaffa Levente - - 2013
Lactose (1,4-0-β-D-galactopyranosyl-D-glucose) is used as a soluble carbon source for the production of cellulases and hemicellulases for-among other purposes-use in biofuel and biorefinery industries. The mechanism how lactose induces cellulase formation in T. reesei is enigmatic, however. Previous results from our laboratory raised the hypothesis that intermediates from the two ...
Sofi F - - 2013
Background/Objectives:Khorasan wheat (Kamut) is an ancient grain with widely acclaimed beneficial effects on human health. The objective was to characterise Kamut and to examine the effect of a replacement diet with their products on cardiovascular risk parameters.Subjects/Methods:We conducted a randomized, single-blinded cross-over trial with two intervention phases on 22 healthy ...
Lervik Anders - - 2013
We analyse a kinetic cycle of the Ca(2+)-ATPase molecular pump using mesoscopic non-equilibrium thermodynamics. The pump is known to generate heat, and by analysing the operation on the mesoscopic level, we are able to introduce a temperature difference and the corresponding heat flux in the description. Integration over the internal ...
Schimmöller L L Department of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, Moorenstrasse 5, 40225 Dusseldorf, - - 2013
Organ-specific dose reduction (OSDR) algorithms can reduce radiation on radiosensitive organs up to 59 %. This study evaluates the influence of a new OSDR algorithm on image quality of head and neck computed tomographic angiography (CTA) in clinical routine. Sixty-two consecutive patients (68 ± 13 years) were randomised into two ...
Gaedcke J - - 2013
INTRODUCTION: Giant inguinoscrotal hernias are rare but still exist even in developed countries. Although accompanied by a higher perioperative mortality, an elective surgical approach should be undertaken. In critically ill patients, however, the surgical intervention requires specific demands. METHODS: We report a case of a 45-year-old man who was referred ...
Gibson Elizabeth A - - 2013
Photoactive NiO electrodes for cathodic dye-sensitised solar cells (p-DSCs) have been prepared with thicknesses ranging between 0.4 and 3.0 μm by spray-depositing pre-formed NiO nanoparticles on fluorine-doped tin oxide (FTO) coated glass substrates. The larger thicknesses were obtained in sequential sintering steps using a conventional furnace (CS) and a newly ...
Ribera E - - 2013
OBJECTIVES: Lipoatrophy is a long-term adverse effect of some antiretrovirals that affects quality of life, compromises adherence and may limit the clinical impact of HIV treatments. This paper explores the effect of tenofovir/emtricitabine (TDF/FTC) on the amount of limb fat in patients with virological suppression. METHODS: A randomized, prospective clinical ...
Sarkhosh Kourosh - - 2013
There is a strong relationship between obesity and the development of obstructive sleep apnea (OSA). Respectively, bariatric surgery is often touted as the most effective option for treating obesity and its comorbidities, including OSA. Nevertheless, there remains paucity of data in the literature of the comparison of all the specific ...
Caro L M - - 2013
Local adaptation of populations along elevational gradients is well known, but conclusive evidence that such divergence has resulted in the origin of distinct species in parapatry remains lacking. We integrated morphological, vocal, genetic and behavioural data to test predictions pertaining to the hypothesis of parapatric ecological speciation associated with elevation ...
Jensen Hanne Irene - - 2013
When making end-of-life decisions in intensive care units (ICUs), different staff groups have different roles in the decision-making process and may not always assess the situation in the same way. The aim of this study was to examine the challenges Danish nurses, intensivists, and primary physicians experience with end-of-life decisions ...
Li Ke - - 2013
Although microorganisms, particularly oxygenic phototrophs, are known as the major players in the biogeochemical cycles of elements in desert soil ecosystems and have received extensive attention, still little is known about the effects of salinity on the composition and abundances of microbial community in desert soils. In this study, the ...
Lauritsen Marlene Briciet - - 2013
The revision of the diagnostic criteria for ASD has been widely anticipated and is expected to be an important contribution to the refinement of the definition of ASD. In the upcoming DSM-5, several changes have been made compared to the previous diagnostic criteria. They include no emphasis on language delay ...
Bao Anyu - - 2013
It has been previously demonstrated that vitamin D acts as a prognostic indicator of gastric cancer and may be correlated with the incidence risk of gastric cancer. However, the effect of 1,25-dihydroxyvitamin D3 on the apoptosis of human gastric cancer cells is unclear. The aim of this study was to ...
Thacker Philip - - 2013
This experiment determined the effects of including normal and low-phytate peas in diets fed to young broiler chickens on performance, phosphorus availability and bone strength. A total of 180, day-old, male broilers (Ross-308 line) were assigned to six treatments. The control was based on corn and soybean meal while two ...
Mohammadi-Sangcheshmeh Abdollah - - 2013
Adipose-derived stem cells are an attractive alternative as a source of stem cells that can easily be extracted from adipose tissue. Isolation, characterization, and multi-lineage differentiation of adipose-derived stem cells have been described for human and a number of other species. Here we aimed to isolate and characterize camel adipose-derived ...
Gorjiara Tina - - 2013
To investigate the radiological water equivalency of three different formulations of the radiochromic, polyurethane based dosimeter PRESAGE(®) for three dimensional (3D) dosimetry of electron beams. The EGSnrc/BEAMnrc Monte Carlo package was used to model 6-20 MeV electron beams and calculate the corresponding doses delivered in the three different PRESAGE(®) formulations and ...
Derbali M - - 2013
The objective of this study was to evaluate the systemic insecticidal activity of an imidacloprid-treated rodent oral bait, against Phlebotomus papatasi Scopoli, 1786 vector of Leishmania major Yakimoff & Schokhor, 1914 (Kinetoplastida: Trypanosomatidae), etiologic agent of zoonotic cutaneous leishmaniasis (ZCL). Shaw's gerbil Meriones shawi Duvernoy, 1842 (Rodentia, Gerbillidae) were treated ...
Lannoy Nathalie N Center of Human Genetics UCLouvain, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium. - - 2013
The intron 22 inversion found in up to 50% of severe hemophilia A patients results from a recombination between three intron 22 homologous copies (int22h). This study evaluated the implication of these copies in the formation of extended duplications comprising exons 1-22 of the factor 8 (F8) gene and their ...
Keskin Emre - - 2013
Negative impacts of introduced non-native freshwater species on native species have been increasingly recognized in the world as well as in Turkey. However, there has been relatively little attention on genetic characterization of alien freshwater fishes in their non-native distribution range and virtually no study has been conducted in Turkey ...
Ferreira L - - 2013
The use of medium-chain triglycerides (MCTs) has been studied for years in an attempt to elucidate their effects in food intake and body weight in animals. The aim of this study was to determine whether there is evidence that the use of MCT reduces consumption and body weight gain in ...
Lubyk Danielle M - - 2013
Although geometric reorientation has been extensively studied in numerous species, most research has been conducted in enclosed environments and has focused on use of the geometric property of relative wall length. The current studies investigated how angular information is used by adult humans and pigeons to orient and find a ...
Vasilopoulos Terrie T Department of Psychiatry & Behavioral Neuroscience, University of Chicago, 5841 S. Maryland Avenue, MC 3077 CNPRU, Chicago, IL 60637, USA. - - 2013
We examined shared and distinct genetic influences among standard measures of pulmonary functions: ratio of forced expiratory volume at 1 s to forced vital capacity (FEV1/FVC) and percent predicted values for forced expiratory volume at 1 s (FEV1%p), forced expiratory flow (FEFmax%p), and maximal voluntary ventilation (MVV%p) in 978-1,048 middle-aged ...
Li X - - 2013
IL-17-producing CD8(+) T lymphocytes (Tc17 cells) have recently been detected in many cancers and autoimmune diseases. However, the possible implication of Tc17 cells in tuberculous pleural effusion remains unclarified. In this study, distribution and phenotypic features of Tc17 cells in both tuberculous pleural effusion (TPE) and peripheral blood from patients ...
Kamson David O DO PET Center and Translational Imaging Laboratory, Children's Hospital of Michigan, Detroit, MI, - - 2013
Pretreatment delineation of infiltrating glioma volume remains suboptimal with current neuroimaging techniques. Gadolinium-enhanced T1-weighted (T1-Gad) MR images often underestimate the true extent of the tumor, while T2-weighted images preferentially highlight peritumoral edema. Accumulation of α-[(11)C]methyl-L-tryptophan (AMT) on positron emission tomography (PET) has been shown in gliomas. To determine whether increased ...
Cook Mary N - - 2013
There are currently no manualized, intensive outpatient programs (IOP), for diagnostically heterogeneous pediatric samples that simultaneously intervene with youth and parents. Such a program was developed and has been operating at Children's Hospital Colorado since January 2006. The current study was conducted to characterize the patient sample and evaluate clinical ...
Boulton Jacqueline - - 2013
Meningitis, defined as the inflammation of the lining surrounding the spine and the brain, can be caused by bacteria, viruses and fungi. Bacterial meningitis is the most serious form of the disease, causing around 170000 deaths worldwide each year. Most cases of bacterial meningitis are caused by three bacteria-Streptococcus pneumoniae, ...
Gopal R - - 2013
The variable efficacy of tuberculosis (TB) vaccines and the emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb) emphasize the urgency for not only generating new and more effective vaccines against TB but also understanding the underlying mechanisms that mediate vaccine-induced protection. We demonstrate that mucosal adjuvants, such as type II ...
Myhrinder Anna Lanemo - - 2013
Abstract Chronic lymphocytic leukemia (CLL) B-cells resemble self-renewing CD5(+) B-cells carrying auto/xeno-antigen-reactive B-cell receptors (BCRs), and multiple innate pattern-recognition receptors, such as Toll-like receptors and scavenger-receptors. Integration of signals from BCRs with multiple surface membrane-receptors determines whether the cells will be proliferating, anergic, or apoptotic. To better understand to role ...
Xue Baoming - - 2013
Concentrations, distributions and sources of PAHs were investigated in surface sediments from Lijiang River, South China. The total PAHs concentrations ranged from 160  to 602 ng g(-1) dry weight.The total PAHs concentrations from different area descended in the order: middle reach > upper reach > down reach. Based on the PAHs indicators ...
Andree K B - - 2013
Inspections by customs agents at Barcelona airport discovered 420 kg of contraband glass eels prepared for shipment to Hong Kong. After confiscation of these animals by police, they were transported to holding facilities to be maintained until after a judicial hearing. Upon arrival, they were separated into two groups and held ...
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