Search Results
Results 251 - 300 of 3239
< 1 2 3 4 5 6 7 8 9 10 11 >
Schimmöller L - - 2013
OBJECTIVES: Organ-specific dose reduction (OSDR) algorithms can reduce radiation on radiosensitive organs up to 59 %. This study evaluates the influence of a new OSDR algorithm on image quality of head and neck computed tomographic angiography (CTA) in clinical routine. METHODS: Sixty-two consecutive patients (68 ± 13 years) were randomised into two groups and ...
Gaedcke J - - 2013
INTRODUCTION: Giant inguinoscrotal hernias are rare but still exist even in developed countries. Although accompanied by a higher perioperative mortality, an elective surgical approach should be undertaken. In critically ill patients, however, the surgical intervention requires specific demands. METHODS: We report a case of a 45-year-old man who was referred ...
Challis S - - 2013
OBJECTIVE: Attempted suicide and deliberate self-injury can occur before or after presentation with a first-episode of psychosis. The aim of the study is to identify the factors associated with suicide attempts or deliberate self-injury before and after treatment for first-episode psychosis. METHOD: A systematic review and meta-analysis of controlled studies ...
Ceschi A - - 2013
Methylmethaqualone is a sedative designer drug created by adding a methyl group to the 3-phenyl ring of methaqualone, and is at present not subject to restrictive regulation in many countries. To our knowledge, no case of methylmethaqualone abuse has been published to date in the scientific literature, and the only ...
Chen Lei - - 2013
MicroRNAs (miRNAs), small non-protein-coding RNA molecules, modulate target gene expression by binding to 3'untranslated regions (UTR) of target mRNA. These molecules are aberrantly expressed in many human cancers, and can function either as tumor suppressors or oncogenes. In the current study, we show that miR-107 is down-regulated in glioma tissues ...
Sukalovic Vladimir - - 2013
Interest in structure-based G-protein-coupled receptor (GPCR) ligand discovery is huge, given that almost 30 % of all approved drugs belong to this category of active compounds. The GPCR family includes the dopamine receptor subtype D2 (D2DR), but unfortunately-as is true of most GPCRs-no experimental structures are available for these receptors. In ...
Fukui Sadaaki - - 2013
The purpose of this study was to quantitatively examine elements of shared decision making (SDM), and to establish empirical evidence for factors correlated with SDM and the level of agreement between consumer and provider in psychiatric care. Transcripts containing 128 audio-recorded medication check-up visits with eight providers at three community ...
Boulton Jacqueline - - 2013
Meningitis, defined as the inflammation of the lining surrounding the spine and the brain, can be caused by bacteria, viruses and fungi. Bacterial meningitis is the most serious form of the disease, causing around 170000 deaths worldwide each year. Most cases of bacterial meningitis are caused by three bacteria-Streptococcus pneumoniae, ...
Myhrinder Anna Lanemo - - 2013
Abstract Chronic lymphocytic leukemia (CLL) B-cells resemble self-renewing CD5(+) B-cells carrying auto/xeno-antigen-reactive B-cell receptors (BCRs), and multiple innate pattern-recognition receptors, such as Toll-like receptors and scavenger-receptors. Integration of signals from BCRs with multiple surface membrane-receptors determines whether the cells will be proliferating, anergic, or apoptotic. To better understand to role ...
Gorjiara Tina - - 2013
To investigate the radiological water equivalency of three different formulations of the radiochromic, polyurethane based dosimeter PRESAGE(®) for three dimensional (3D) dosimetry of electron beams. The EGSnrc/BEAMnrc Monte Carlo package was used to model 6-20 MeV electron beams and calculate the corresponding doses delivered in the three different PRESAGE(®) formulations and ...
Derbali M - - 2013
The objective of this study was to evaluate the systemic insecticidal activity of an imidacloprid-treated rodent oral bait, against Phlebotomus papatasi Scopoli, 1786 vector of Leishmania major Yakimoff & Schokhor, 1914 (Kinetoplastida: Trypanosomatidae), etiologic agent of zoonotic cutaneous leishmaniasis (ZCL). Shaw's gerbil Meriones shawi Duvernoy, 1842 (Rodentia, Gerbillidae) were treated ...
Lannoy Nathalie - - 2013
The intron 22 inversion found in up to 50% of severe hemophilia A patients results from a recombination between three intron 22 homologous copies (int22h). This study evaluated the implication of these copies in the formation of extended duplications comprising exons 1-22 of the factor 8 (F8) gene and their ...
Forster Myriam - - 2013
Objectives. This article examines the antecedents and consequences of bullying victimization among a sample of Hispanic high school students. Although cultural and familial variables have been examined as potential risk or protective factors for substance use and depression, previous studies have not examined the role of peer victimization in these ...
Keskin Emre - - 2013
Negative impacts of introduced non-native freshwater species on native species have been increasingly recognized in the world as well as in Turkey. However, there has been relatively little attention on genetic characterization of alien freshwater fishes in their non-native distribution range and virtually no study has been conducted in Turkey ...
Ferreira L - - 2013
The use of medium-chain triglycerides (MCTs) has been studied for years in an attempt to elucidate their effects in food intake and body weight in animals. The aim of this study was to determine whether there is evidence that the use of MCT reduces consumption and body weight gain in ...
Lubyk Danielle M - - 2013
Although geometric reorientation has been extensively studied in numerous species, most research has been conducted in enclosed environments and has focused on use of the geometric property of relative wall length. The current studies investigated how angular information is used by adult humans and pigeons to orient and find a ...
Doody Owen - - 2013
Focus groups are used by researchers in the social and behavioural sciences to explore phenomena and are accepted as a legitimate qualitative methodology. The primary goal of focus groups is to use interaction data resulting from discussion among participants to increase the depth of the enquiry and reveal aspects of ...
Tsilingaridis G - - 2013
BACKGROUND AND OBJECTIVE: Periodontitis is more frequently found in subjects with Down's syndrome. The aim was to investigate whether the relationship between MMPs and TIMPs) in the gingival crevicular fluid of subjects with Down's syndrome is altered compared with controls. MATERIAL AND METHODS: Twenty-one adolescents with Down's syndrome and gingivitis ...
Delord J P - - 2013
PURPOSE: Vinflunine ditartrate is a microtubule inhibitor belonging to the vinca alkaloid family. This phase I study was carried out to evaluate the maximal tolerated dose, the safety profile, the pharmacokinetics and the activity of oral vinflunine (VFL) given daily in patients with advanced/metastatic solid tumours and who have failed ...
Zhang Yujie - - 2013
3-Oxoacyl-(acyl-carrier-protein) reductase (OAR1 or FabG, EC.1.1.1.100) is responsible for the first reductive step in fatty acid biosynthesis using Nicotinamide Adenine Dinucleotide Phosphate (NADPH) as a cofactor. Recent studies suggest there is a fatty acid synthetase II pathway that consists of a series of separate enzymes in yeast mitochondrion. Here, we ...
Dambacher Michael - - 2013
Deadlines (DLs) and response signals (RSs) are two well-established techniques for investigating speed-accuracy trade-offs (SATs). Methodological differences imply, however, that corresponding data do not necessarily reflect equivalent processes. Specifically, the DL procedure grants knowledge about trial-specific time demands and requires responses before a prespecified period has elapsed. In contrast, RS ...
Zhao He-Ping - - 2013
We evaluated a strategy for achieving complete reduction of perchlorate (ClO4-) in the presence of much higher concentrations of sulfate (SO42-) and nitrate (NO3-) in a hydrogen-based membrane biofilm reactor (MBfR). Full ClO4- reduction was achieved by using a two-stage MBfR with controlled NO3- surface loadings to each stage. With ...
Zheleznyakova Galina Y - - 2013
Spinal muscular atrophy (SMA) is a monogenic disorder that is subdivided into four different types and caused by survival motor neuron gene 1 (SMN1) deletion. Discordant cases of SMA suggest that there exist additional severity modifying factors, apart from the SMN2 gene copy number. Here we performed the first genome-wide ...
Yu Yang - - 2013
Human glutathione transferase zeta 1c-1c (hGSTZ1c-1c) is one of the glutathione transferase isoenzymes and considered to be a protein scaffold to imitate glutathione peroxidase (GPX) owing to the natural binding site of glutathione (GSH). In this report, several residues near GSH were mutated to selenocysteine (Sec) or cysteine (Cys) residues ...
Bersamin Andrea - - 2013
Objectives. American Indians and Alaska Natives (ANs) report among the lowest levels of physical activity in the USA, but there is very little systematic research examining the determinants of physical activity patterns in these populations. This study investigated the relationships between enculturation (or cultural traditionality), psychosocial stress, and physical activity ...
Viaene Liesbeth - - 2013
Indoxyl sulfate and p-cresyl sulfate are two uremic retention solutes implicated in the uremic syndrome. Removal during dialysis is limited, mainly due to protein binding. Binding characteristics to healthy albumin have recently been characterized. Whether uremia alters the binding characteristics of albumin, is currently unknown. Moreover, protein binding values previously ...
Brillet Pierre-Yves - - 2013
OBJECTIVES: To assess the association between airway wall area and clinical asthma control, assessed by the Asthma Control Test (ACT). METHODS: This cross-sectional study evaluated 96 adults for asthma control ["at least well controlled" (ACT ≥ 20; n = 52) or "not well controlled" (ACT < 20; n = 44) ...
Maas Matthew B - - 2013
BACKGROUND: Anticoagulation increases the risk of intracerebral hemorrhage (ICH), yet whether different underlying disease processes are equally affected is unknown. We tested the hypothesis that coagulopathy, measured by admission international normalized ratio (INR), disproportionately increases the risk for lobar hemorrhages. METHODS: Patients with primary ICH were enrolled into a registry ...
Rai Rewa - - 2013
The ring closing metathesis within an ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF(6)]), a 'green' solvent tetraethylene glycol (TEG), and their equimolar mixture is investigated through the intramolecular excimer formation of 6-(1-pyrenyl)hexyl-11-(1-pyrenyl)undecanoate []. The excimer formation efficiency correlates directly with the inverse of the bulk viscosity of the systems. A simplistic double ...
Venditti Alessandro - - 2013
The phytochemical study of the polar fraction of Bellardia trixago (L.) All. led to the isolation of eight iridoid glucosides. Five of these glucosides (aucubin (1), bartsioside (2), melampyroside (3), mussaenoside (4) and gardoside methyl ester (5)) were confirmed as they were previously isolated from this plant, and the remaining ...
Witsch J - - 2013
We aimed to determine long-term disability and quality of life in patients with Guillain-Barré syndrome (GBS) who required mechanical ventilation (MV) in the acute phase. Our retrospective cohort study included 110 GBS patients admitted to an intensive care unit and requiring MV (01/1999-08/2010) in nine German tertiary academic medical centers. ...
Patel Nitin R - - 2013
We describe a value-driven approach to optimizing pharmaceutical portfolios. Our approach incorporates inputs from research and development and commercial functions by simultaneously addressing internal and external factors. This approach differentiates itself from current practices in that it recognizes the impact of study design parameters, sample size in particular, on the ...
Iriarte Andrés - - 2013
Many studies have explored the mechanisms involved in relative amino acid usage (RAAU) in a variety of prokaryotes and eukaryotes. A strong bias was observed in highly expressed genes (HEGs) of endosymbiotic bacteria. By means of correspondence analysis, we studied the major trends affecting internal variability of RAAU in Mollicutes. ...
Rosenberg Monica - - 2013
Sustained attention is a fundamental aspect of human cognition and has been widely studied in applied and clinical contexts. Despite a growing understanding of how attention varies throughout task performance, moment-to-moment fluctuations are often difficult to assess. In order to better characterize fluctuations in sustained visual attention, in the present ...
Gallo A - - 2013
A set of 180 forages (47 alfalfa hays, 26 grass hays, 52 corn silages, 35 small grain silages and 20 sorghum silages) were randomly collected from different locations of the Po Valley (Northern Italy) from 2009 to 2010. The forages were characterised for chemical composition (11 parameters), NDF digestibility (five ...
Ohkawa Shingo - - 2013
Skeletal muscle injuries often leave lasting functional damage or pain. Muscle injuries are routinely treated conservatively, but the most effective treatment to promote the repair of injured muscles has not yet been established. Our previous report demonstrated that human peripheral blood-derived CD133+ cell transplantation to rat skeletal muscle injury models ...
Kim Hyo Jung - - 2013
Liquorice is one of the botanicals used frequently as a traditional medicine in the West and in the East. Platelet-derived growth factor (PDGF)-BB is involved in the development of CVD by inducing abnormal proliferation and migration of vascular smooth muscle cells. In our preliminary study, dehydroglyasperin C (DGC), an active ...
Furtula Jasna - - 2013
The objective of this study was to evaluate the diagnostic value of triple stimulation technique (TST) and diffusion tensor imaging (DTI) tractography as markers of upper motor neuron (UMN) degeneration in amyotrophic lateral sclerosis (ALS). Fourteen ALS patients fulfilling the El Escorial criteria and 30 control subjects participated in the ...
Zhang Yongguo - - 2013
BACKGROUND: Deleted in breast cancer 1 (DBC1) was initially cloned from a region homozygously deleted in breast cancers, but its role in colorectal cancer remains unknown. The present study aims to examine the expression level of DBC1 and assess its prognostic value in human colorectal cancer. METHODS: Immunohistochemical staining was ...
Vidal-Martínez V M - - 2013
Global climate change (GCC) is expected to affect key environmental variables such as temperature and rainfall, which in turn influence the infection dynamics of metazoan parasites in tropical aquatic hosts. Thus, our aim was to determine how temporal patterns of temperature and rainfall influence the mean abundance and aggregation of ...
Alexis Obrey - - 2013
This article explores the importance of drug administration and some of the key legislation that relates to it. It focuses on the accountability and responsibility of qualified nurse and student nurses. The author also draws on the notion of informed consent and what that means in the health care setting. ...
Ahmadiantehrani Somayeh - - 2013
Glial cell line-derived neurotrophic factor (GDNF) is a potent inhibitor of ethanol consumption and relapse, and GDNF heterozygous knockout mice display increased reward sensitivity to ethanol and consume more ethanol after a period of abstinence than their wild-type littermates. Here, we tested whether ethanol alters GDNF expression in the ventral ...
Ladurner Roland - - 2013
BACKGROUND: In this study, we evaluate a new bioadhesive for intra-abdominal onlay mesh fixation of a polypropylene-polyvinylchloride graft. METHODS: Three pieces of a commercially available polypropylene/polyvinylfluoride mesh, each 3 × 3 cm in size, and three pieces of the same mesh coated with a polysaccharide bioadhesive were fixated to the surface of the ...
Li Qipei - - 2013
A Gram-negative, rod-shaped, non-spore-forming aerobic bacterium, motile with a single polar flagellum, strain JLT2005(T), was isolated from surface seawater collected from the East China Sea and formed ivory white colonies on a rich organic medium. The strain was positive for catalase, oxidase, and urease. It grew in the presence of ...
Walsh Erin M - - 2013
Fewer than half of Americans meet current recommendations for fruit and vegetable intake. The behavioral affective associations model posits that feelings and emotions associated with a behavior are a proximal influence on decision making. Cross-sectional evidence supports the model and suggests that affective associations predict fruit and vegetable consumption. The ...
Kaya Selçuk - - 2013
The aim of this study was to evaluate the effectiveness of daptomycin in left-sided infective endocarditis (IE) patients. Fourteen patients with left heart endocarditis, monitored with a diagnosis of IE based on modified Duke criteria between July 2010 and May 2011, and receiving daptomycin as monotherapy, were enrolled. The success ...
Kim H-H - - 2013
The objectives of this study were to survey elementary school students regarding the environmental conditions of their elementary schools and to assess the relationship between air pollution and allergic disease using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Therefore, this study was designed as a cross-sectional ...
Chen Yang - - 2013
Prostate cancer (PCa) is a worldwide disease that affects a large number of males. Although prostate-specific antigen (PSA) screening is used, the specificity is limited. This study analyzes the sensitivity and specificity of adenomatous polyposis coli (APC) methylation for PCa detection in body fluids and tissues. Combining search results from ...
Bahri F - - 2013
This study describes the chemical composition and antibacterial activities of essential oils of Moroccan Juniperus thurifera L. var. Africana (Cupressaceae). The essential oil of dried leaves was isolated by hydrodistillation, vapohydrodistillation and microwaves. Sixty-four compounds in J. thurifera L. var. Africana oils were identified (79.9%, 92.4% and 98.4% of the ...
Kirkwood Michael W - - 2013
In adult populations, embedded performance validity indicators are well established, as they are time efficient, resistant to coaching, and allow for more continuous monitoring of effort than standalone measures. Although several recent studies have demonstrated the appropriateness of using standalone validity tests with school-age children, a paucity of pediatric work ...
< 1 2 3 4 5 6 7 8 9 10 11 >