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Results 201 - 250 of 3241
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Bae Yun Jung - - 2013
OBJECTIVE: To provide magnetic resonance imaging (MRI) findings of compressive myelopathy simulating idiopathic acute transverse myelopathy (ATM). MATERIALS AND METHODS: From 19,416 patients who had spinal MRI from 1 September 2004 to 10 July 2011, the patients who met inclusion criteria were enrolled as follows: (1) definable cord compression, (2) ...
Kushner M G - - 2013
BACKGROUND: Clinical trials are typically designed to test the effect of a specific treatment on a single diagnostic entity. However, because common internalizing disorders are highly correlated ('co-morbid'), we sought to establish a practical and parsimonious method to characterize and quantify changes in a broad spectrum of internalizing psychopathology targeted ...
Walentiny D M - - 2013
BACKGROUND AND PURPOSE: Previous structure activity relationship studies with analogs of the CB(1) receptor antagonist rimonabant have demonstrated that a subset of these analogs with 3-substituent replacements of rimonabant's pyrazole core displayed cannabimimetic profiles seemingly independent of CB(1) receptors. We sought to further evaluate these analogs in several behavioral models ...
Peterhänsel C - - 2013
Bariatric surgery is one of the most effective treatments for morbid obesity, and a large body of research indicates significant long-term weight loss. While overall mortality decreases in patients who received bariatric surgery, a number of studies have shown that suicide rates are higher in bariatric patients than in control ...
Vasilopoulos Terrie - - 2013
We examined shared and distinct genetic influences among standard measures of pulmonary functions: ratio of forced expiratory volume at 1 s to forced vital capacity (FEV1/FVC) and percent predicted values for forced expiratory volume at 1 s (FEV1%p), forced expiratory flow (FEFmax%p), and maximal voluntary ventilation (MVV%p) in 978-1,048 middle-aged (mean age = 55 years) ...
Li X - - 2013
IL-17-producing CD8(+) T lymphocytes (Tc17 cells) have recently been detected in many cancers and autoimmune diseases. However, the possible implication of Tc17 cells in tuberculous pleural effusion remains unclarified. In this study, distribution and phenotypic features of Tc17 cells in both tuberculous pleural effusion (TPE) and peripheral blood from patients ...
Cook Mary N - - 2013
There are currently no manualized, intensive outpatient programs (IOP), for diagnostically heterogeneous pediatric samples that simultaneously intervene with youth and parents. Such a program was developed and has been operating at Children's Hospital Colorado since January 2006. The current study was conducted to characterize the patient sample and evaluate clinical ...
Dalton Mark Anthony - - 2013
Abstract Aim: To explore perceptions of junior doctors, nurses and advanced nurse practitioners (ANP) in relation to the role of the ANP. Method: A qualitative cross-sectional design was used, embedded in an interpretative philosophy. A non-probability sample of six junior doctors, six ward nurses and six ANPs took part in ...
Lee Kang Hong - - 2013
BACKGROUND: We assessed the short- and long-term outcomes of intracorporeal ileocolic anastomosis (IA) in laparoscopic right hemicolectomy for colon cancer compared with extracorporeal anastomosis (EA). METHODS: A retrospective chart review of 86 consecutive patients who underwent laparoscopic right hemicolectomy for colon cancer from March 2005 to June 2010 was performed. ...
Mudge Stephen R - - 2013
Isomaltulose (IM) is a natural isomer of sucrose. It is widely approved as a food with properties including slower digestion, lower glycaemic index and low cariogenicity, which can benefit consumers. Availability is currently limited by the cost of fermentative conversion from sucrose. Transgenic sugarcane plants with developmentally-controlled expression of a ...
Ding Wei-Feng - - 2013
A new cell line named RIRI-PaDe, developed from the neonate larvae of Papilio demoleus Linnaeus, was established in modified Grace's medium supplemented with 20% fetal bovine serum. The cell line was incubated at 28°C and consisted of attached round and short spindle-like cells. The population doubling time was 55 h. The ...
Zhou Hui - - 2013
Jatrorrhizine, one of the protoberberine alkaloids derived from the plant Coptis chinensis, is expected to be developed as a new gastric prokinetic drug, but its metabolic characteristics in humans remain unknown. This study characterized the phase I and phase II metabolites, metabolic kinetics, and cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) ...
Gaillard Jean-Michel - - 2013
How populations respond to climate change depends on the interplay between life history, resource availability, and the intensity of the change. Roe deer are income breeders, with high levels of allocation to reproduction, and are hence strongly constrained by the availability of high quality resources during spring. We investigated how ...
Hayes Lesley - - 2013
The Florence Nightingale Foundation Trust awarded me a travel scholarship in 2012. This enabled me to undertake visits to link with a range of health and social care professionals, services and universities in Spain and America (Houston and Louisville), with the aim of exploring the nature and management of self-neglect ...
Hanlidou Effie - - 2013
Thymus leucospermus Hartvig is a Greek endemic species of Section Teucrioides Jalas. The essential oils obtained from five populations growing wild in the National Park of Northern Pindhos (NW Greece) were studied. The oil content ranged between 1.1 and 2.0 mL per 100 g of dry plant weight. The oils were particularly ...
Hashem N M - - 2013
This study was designed to study the effect of short-term supplementation with rumen-protected fat during the late luteal phase on reproduction and metabolism of sheep during breeding season. Seventy-six ewes (Rahmani, Barki and Awassi × Barki) were allocated to two groups considering genotype: the control ewes (C-group) received a maintenance diet, and ...
Arnau Jaume - - 2013
This study analyzes the robustness of the linear mixed model (LMM) with the Kenward-Roger (KR) procedure to violations of normality and sphericity when used in split-plot designs with small sample sizes. Specifically, it explores the independent effect of skewness and kurtosis on KR robustness for the values of skewness and ...
Lambert Carey - - 2013
Bdellovibrio bacteriovorus are predatory bacteria that burrow into prey bacteria and degrade their cell contents, including DNA and RNA, to use for growth. Their genome encodes diverse nucleases, some with potential export sequences. Transcriptomic analysis determined two candidate predicted nuclease genes (bd1244, bd1934) upregulated upon contact with prey; which, we ...
Huh Jin - - 2013
BACKGROUND: Intermittent pneumatic compression (IPC) devices have been widely used for thrombosis prophylaxis in laparoscopic colorectal surgery. However, periodic compression using an IPC device may inject augmented boluses of cool blood from the lower limbs into the central circulation repetitively, thereby causing a reduction in core temperature. The authors therefore ...
Akça Oktay - - 2013
AIM: Although the management of urinary stones in obese patients is a challenge and the impact of the patient-related parameter has been well studied in adults: No study has evaluated the possible impact of obesity in terms of body mass index related SWL success in pediatric population. In this present ...
Willard James J - - 2013
Tissue engineering scaffolds are commonly formed using proteins extracted from animal tissues such as bovine hide. Risks associated with the use of these materials include hypersensitivity, and pathogenic contamination. Human-derived proteins lower the risk of hypersensitivity but possess the risk of disease transmission. Methods engineer recombinant human proteins using plant ...
Kim Jeong-Min - - 2013
Cancer related stroke may have different phenotypes from non-cancer stroke, especially in terms of stroke progression and recurrence. We performed a case-control study to identify their incidences and risk factors in cancer related stroke. Between January 2001 and December 2009, we conducted a retrospective review of acute ischemic stroke patients ...
Zhou Qi - - 2013
PURPOSE: To examine the prevalence of systemic and ocular disease among choroideremia patients and carriers. METHODS: A cross-sectional analysis was performed on responses from affected males with choroideremia, female carriers, and unaffected brothers to an Internet-based survey made available from September 2009 to November 2010. Affected males were classified into ...
Bougas B - - 2013
Parental effects represent an important source of variation in offspring phenotypes. Depending on the specific mechanisms involved, parental effects may be caused to different degrees by either the maternal or the paternal parent, and these effects may in turn act at different stages of development. To detect parental effects acting ...
Campos Alline C - - 2013
Cannabidiol (CBD), the main non-psychotomimetic component of the plant Cannabis sativa, exerts therapeutically promising effects on human mental health such as inhibition of psychosis, anxiety and depression. However, the mechanistic bases of CBD action are unclear. Here we investigate the potential involvement of hippocampal neurogenesis in the anxiolytic effect of ...
Merwood A - - 2013
BACKGROUND: Parent and teacher ratings of attention deficit hyperactivity disorder (ADHD) symptoms yield high estimates of heritability whereas self-ratings typically yield lower estimates. To understand why, the present study examined the etiological overlap between parent, teacher and self-ratings of ADHD symptoms in a population-based sample of 11-12-year-old twins. Method Participants ...
Bousleiman Habib - - 2013
This paper presents a firsthand comparative evaluation of three different existing methods for selecting a suitable allograft from a bone storage bank. The three examined methods are manual selection, automatic volume-based registration, and automatic surface-based registration. Although the methods were originally published for different bones, they were adapted to be ...
Landires Ivan - - 2013
The subcellular localization of JAK3 was examined by quantitative image analysis. For the first time, JAK3 was found to be located in the nuclei of primary CD4 lymphocytes. A comparable quantity of JAK3 was recovered in CD4 lymphocytes from healthy donors and HIV-infected patients. By contrast, far more phosphorylated JAK3 ...
Zamani Payman - - 2013
Heart failure is an important public health problem that is increasing in prevalence throughout the world. Not only is this condition common, but it is associated with significant morbidity and mortality as well as high costs to medical care systems. Vasodilator drugs help unload the heart and may have other ...
Pirker Robert - - 2013
Several monoclonal antibodies directed against the epidermal growth factor receptor (EGFR) have been evaluated in patients with non-small cell lung cancer (NSCLC). Cetuximab, a chimeric monoclonal antibody, has been studied in combination with first-line chemotherapy in phase II and two phase III trials in patients with advanced NSCLC. The phase ...
Basson Helena Aletta - - 2013
Purpose: The development of a framework for a workplace wellness programme for HIV/AIDS infected and/or affected nurses in South Africa, who comprise registered nurses and midwives, enrolled staff nurses and auxiliary nurses. Research objectives: To identify and describe components for a framework of a workplace wellness programme. Background: Registered nurses ...
Castro-Gamero Angel Mauricio - - 2013
Glioblastoma (GBM), one of the most malignant human neoplasias, responds poorly to current treatment modalities, with temozolomide (TMZ) being the drug most frequently used for its treatment. Tetra-O-methyl Nordihydroguaiaretic Acid (M4N) is a global transcriptional repressor of genes dependent on the Sp1 transcription factor, such as Survivin and Cdk1. In ...
Reddy Gaddum D - - 2013
PURPOSE: Cerebellar glioblastomas in children are rare. As a result, an optimal treatment strategy has not yet been identified. A review of the characteristics of the disease as well as the effectiveness of various therapeutic modalities would help in optimizing the treatment paradigm. METHODS: We performed a detailed clinical, radiographic, ...
Yoshida R - - 2013
A new rhizocephalan species of the genus Dipterosaccus Van Kampen & Boschma, 1925, is described from the host hermit crab Calcinus vachoni Forest on the coasts of mainland Japan and the Ryukyu Archipelago. Dipterosaccus shiinoi n. sp. differs from the previously described species, D. indicus Van Kampen & Boschma, 1925, ...
Tang Baokun - - 2013
Bioethanol is considered a potential liquid fuel that can be produced from biomass by fermentation and distillation. Although most of the water is removed by distillation, the purity of ethanol is limited to 95-96 % due to the formation of a low-boiling point, water-ethanol azeotrope. To improve the use of ethanol ...
Khashab Mouen - - 2013
BACKGROUND AND AIMS: Endoscopic placement of enteral self-expandable metallic stents is an alternative to surgical gastrojejunostomy (GJ) for palliation of malignant gastric outlet obstruction (GOO). Factors associated with clinical outcomes are not known. The aims of this study are to compare the overall complication rate and effectiveness (duration of oral ...
Leow J J - - 2013
Obturator hernia is a rare surgical condition, with about 800 cases being reported in the literature. It can cause significant morbidity and mortality, especially in the elderly age group. Delayed treatment is associated with high rates of strangulation (25-100 %). The mainstay of management for obturator hernia has been surgical. Non-operative ...
Tripathi Pankaj - - 2013
Abstract The present study investigated the protective effects of Syzygium cumini extract (SCE; 100 and 200 mg/kg) against genotoxicity and oxidative stress (OS) induced by cyclophosphamide (CP) in mice. Animals were received 14 days pretreatment (oral) of SCE, followed by induction of genotoxicity by CP (40 mg/kg), 24 hours before sacrifice. Mice ...
Karaffa Levente - - 2013
Lactose (1,4-0-β-D-galactopyranosyl-D-glucose) is used as a soluble carbon source for the production of cellulases and hemicellulases for-among other purposes-use in biofuel and biorefinery industries. The mechanism how lactose induces cellulase formation in T. reesei is enigmatic, however. Previous results from our laboratory raised the hypothesis that intermediates from the two ...
Sofi F - - 2013
Background/Objectives:Khorasan wheat (Kamut) is an ancient grain with widely acclaimed beneficial effects on human health. The objective was to characterise Kamut and to examine the effect of a replacement diet with their products on cardiovascular risk parameters.Subjects/Methods:We conducted a randomized, single-blinded cross-over trial with two intervention phases on 22 healthy ...
Lervik Anders - - 2013
We analyse a kinetic cycle of the Ca(2+)-ATPase molecular pump using mesoscopic non-equilibrium thermodynamics. The pump is known to generate heat, and by analysing the operation on the mesoscopic level, we are able to introduce a temperature difference and the corresponding heat flux in the description. Integration over the internal ...
Schimmöller L - - 2013
OBJECTIVES: Organ-specific dose reduction (OSDR) algorithms can reduce radiation on radiosensitive organs up to 59 %. This study evaluates the influence of a new OSDR algorithm on image quality of head and neck computed tomographic angiography (CTA) in clinical routine. METHODS: Sixty-two consecutive patients (68 ± 13 years) were randomised into two groups and ...
Gaedcke J - - 2013
INTRODUCTION: Giant inguinoscrotal hernias are rare but still exist even in developed countries. Although accompanied by a higher perioperative mortality, an elective surgical approach should be undertaken. In critically ill patients, however, the surgical intervention requires specific demands. METHODS: We report a case of a 45-year-old man who was referred ...
Challis S - - 2013
OBJECTIVE: Attempted suicide and deliberate self-injury can occur before or after presentation with a first-episode of psychosis. The aim of the study is to identify the factors associated with suicide attempts or deliberate self-injury before and after treatment for first-episode psychosis. METHOD: A systematic review and meta-analysis of controlled studies ...
Ceschi A - - 2013
Methylmethaqualone is a sedative designer drug created by adding a methyl group to the 3-phenyl ring of methaqualone, and is at present not subject to restrictive regulation in many countries. To our knowledge, no case of methylmethaqualone abuse has been published to date in the scientific literature, and the only ...
Chen Lei - - 2013
MicroRNAs (miRNAs), small non-protein-coding RNA molecules, modulate target gene expression by binding to 3'untranslated regions (UTR) of target mRNA. These molecules are aberrantly expressed in many human cancers, and can function either as tumor suppressors or oncogenes. In the current study, we show that miR-107 is down-regulated in glioma tissues ...
Sukalovic Vladimir - - 2013
Interest in structure-based G-protein-coupled receptor (GPCR) ligand discovery is huge, given that almost 30 % of all approved drugs belong to this category of active compounds. The GPCR family includes the dopamine receptor subtype D2 (D2DR), but unfortunately-as is true of most GPCRs-no experimental structures are available for these receptors. In ...
Fukui Sadaaki - - 2013
The purpose of this study was to quantitatively examine elements of shared decision making (SDM), and to establish empirical evidence for factors correlated with SDM and the level of agreement between consumer and provider in psychiatric care. Transcripts containing 128 audio-recorded medication check-up visits with eight providers at three community ...
Boulton Jacqueline - - 2013
Meningitis, defined as the inflammation of the lining surrounding the spine and the brain, can be caused by bacteria, viruses and fungi. Bacterial meningitis is the most serious form of the disease, causing around 170000 deaths worldwide each year. Most cases of bacterial meningitis are caused by three bacteria-Streptococcus pneumoniae, ...
Myhrinder Anna Lanemo - - 2013
Abstract Chronic lymphocytic leukemia (CLL) B-cells resemble self-renewing CD5(+) B-cells carrying auto/xeno-antigen-reactive B-cell receptors (BCRs), and multiple innate pattern-recognition receptors, such as Toll-like receptors and scavenger-receptors. Integration of signals from BCRs with multiple surface membrane-receptors determines whether the cells will be proliferating, anergic, or apoptotic. To better understand to role ...
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