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Jedrychowski Wieslaw A - - 2013
In a birth cohort study, we have assessed the dose-response relationship between individual measurements of prenatal airborne polycyclic aromatic hydrocarbon (PAH) exposure and specific PAH-DNA adducts in cord blood adjusted for maternal blood adducts and season of birth. The study uses data from an earlier established birth cohort of children ...
Montealegre Jane R - - 2013
While Hispanics in the U.S. are a population with significant within-group heterogeneity, epidemiologic studies often aggregate Hispanics into one homogenous group without considering differences by nativity. The objective of this study is to evaluate nativity differences in the risk behavior profile associated with prevalent high risk human papillomavirus (HR-HPV) among ...
McClimens Alex - - 2013
As community-based care has developed in line with current policy towards integrated care, some hospital placement capacity for student health professionals has been lost as a result of service reorganisation. However, student nurses and allied health professionals need to gain a broad range of experience to prepare them for the ...
Bommana Murali Mohan - - 2013
Abstract Objective: Efficacy of a formulation of a poorly soluble centrally acting drug was evaluated by measuring dopamine responses using in vivo brain microdialysis. Methods: Co-crystals (1:1) of carbamazepine and nicotinamide (CBZ-NCT) were complexed with cyclodextrins (γ-CDs) using supercritical fluid processing. Phase solubility and intrinsic dissolution were studied. Pharmacodynamic studies ...
Son Seok Hyun - - 2013
ABSTRACT: BACKGROUND: The purpose of this study was to identify parameters capable of predicting the deterioration of hepatic function after helical tomotherapy in patients with unresectable locally advanced hepatocellular carcinoma. METHODS: Between March 2006 and February 2012, 72 patients were eligible for this study. All patients received hypofractionated radiotherapy using ...
Ghorayeb Sleiman R - - 2013
Several imaging modalities have traditionally been utilized to assess bone health. However, none of these standards is capable of providing a clear rendition or display of the damaged bone layers caused, for instance, by osteoporosis. This study examines the use of ultrasound for non-invasive monitoring of bone quality in bone ...
Lee Jennifer W - - 2013
Abstract Objective: To explore (1) whether extremely low gestational age newborns exposed to inflammation-associated pregnancy disorders differ in retinopathy of prematurity (ROP) risk from infants exposed to placenta dysfunction-associated disorders, and (2) whether ROP risk associated with postnatal hyperoxemia and bacteremia differs among infants exposed to these disorders. Methods: Pregnancy ...
Itman Catherine - - 2013
According to the World Health Organization, a fertile man typically has a sperm count of 15 million per milliliter of semen. This spermatogenic capacity is determined by appropriate specification, proliferation, differentiation, and maturation of somatic and germ cells, events that begin during fetal development and continue throughout adulthood. These processes ...
de Lepper Anne M - - 2013
OBJECTIVE: The use of mobile phones can improve and strengthen (preventive) health care in low- and middle-income countries. We aimed to retrospectively assess the response patterns of participants in free SMS health education quizzes in Uganda. METHODS: Study participants were employees of two companies and their community networks. We investigated ...
Sekhwal Manoj Kumar - - 2013
The antiporters, uniporters and symporters are the functional classes of MFS that play major role in ions homeostasis, regulation of pumps and channels, membrane structure, transporters activity in tolerance to abiotic stresses. Major facilitator superfamily (MFS) encodes Na(+)/H(+) antiporter that are considered as being sensors of the molecule transports. A ...
Poulere Eleni - - 2013
PURPOSE: To compare the effects of defocus induced blur and blur adaptation on visual acuity and to evaluate any differences between emmetropes and myopes using letter and Landolt C logMAR charts. METHODS: The sample consisted of 26 volunteers, with a mean age of 27 ± 3 years, comprising 13 emmetropes (spherical equivalent range: ...
Wakabayashi Kaori - - 2013
A new species of parasitic copepod, Choniomyzon inflatus n. sp., is described based on specimens collected from the external egg masses of the smooth fan lobster Ibacus novemdentatus Gibbes captured in the North Pacific Ocean off Ainan, Ehime Prefecture, western Japan. The new species differs from its congeners in having ...
Wright Michelle F - - 2013
Adolescents experience various forms of strain in their lives that may contribute jointly to their engagement in cyber aggression. However, little attention has been given to this idea. To address this gap in the literature, the present longitudinal study examined the moderating influence of peer rejection on the relationship between ...
Yi Wenchao - - 2013
The objective of the study was to further elucidate the potential mechanisms underlying left hemiparalexia induced by a splenium lesion in corpus callosum. A patient KY, who had infarctions in the splenium and the left ventral medial occipitotemporal area, was examined with neuropsychological tests and fMRI. KY presented left hemiparalexia ...
Serrano C - - 2013
Helicobacter pylori induces less gastric inflammation in children than adults. Here we investigated whether this reduced inflammation involves dysregulated T helper type 17 (Th17) responses. H. pylori-infected children and adults in Santiago, Chile had similar levels of H. pylori colonization, proportions of bacteria containing cagA and s1/s2 vacA markers of ...
Rowson Steven - - 2013
Recent research has suggested possible long term effects due to repetitive concussions, highlighting the importance of developing methods to accurately quantify concussion risk. This study introduces a new injury metric, the combined probability of concussion, which computes the overall risk of concussion based on the peak linear and rotational accelerations ...
Yang Qing - - 2013
Coronary artery disease is the most common type of heart disease and a leading cause of morbidity and mortality all over the world. Acute coronary syndrome (ACS) is the most serious form of coronary artery disease. Recently, many studies indicated that genetic susceptibility may play a vital role in the ...
Kassler Kristin - - 2013
The interaction of the HIV-1 fusion protein gp120 with its cellular receptor CD4 represents a crucial step of the viral infection process, thus rendering gp120 a promising target for the intervention with anti-HIV drugs. Naturally occurring mutations of gp120, however, can decrease its affinity for anti-infective ligands like therapeutic antibodies ...
Billington Tracey - - 2013
Tracey Billington is studying part-time for an MSc Health and Social Care at Northumbria University. She qualified as a mental health nurse in January 2012 and is currently employed as a prison substance misuse nurse. Tracey reflects on how using a self-development diary has helped her to develop her self-awareness ...
van de Vijver Steven - - 2013
Background. An increasing burden of cardiovascular disease (CVD) is occurring in low- and middle-income countries (LMICs) as a result of urbanisation and globalisation. Low rates of awareness and treatment of risk factors worsen the prognosis in these settings. Prevention of CVD is proven to be cost effective and should be ...
Ren Xing-Feng - - 2013
We have developed a series of azadipeptide nitriles with different P3 groups. A triaryl meta-phenyl derivative, compound , was not only a potent inhibitor for cathepsin K (K(i) = 0.0031 nM), but also highly selective over both cathepsins B and S (∼1000-fold). A protein-ligand docking study performed on the series ...
Liljavirta J - - 2013
Due to a limited range of immunoglobulin (Ig) genes, cattle and several other domestic animals rely on postrecombinatorial amplification of the primary repertoire. We report that activation-induced cytidine deaminase (AID) is strongly expressed in the fetal bovine ileal Peyer's patch and spleen but not in fetal bone marrow. The numbers ...
Yapijakis Christos - - 2013
The incidence of basal cell carcinoma (BCC) is significantly reduced in individuals treated with inhibitors of angiotensin I-converting enzyme (ACE) that produces angiotensin II. The objective of this study was to investigate the possible association of a functional polymorphism in the ACE gene, which affects its transcription, with risk for ...
Byun Seung Ok - - 2013
FOXO3 is a member of the FOXO (forkhead box class O) transcription factor family and has roles in cell cycle control, apoptosis, neural and hematopoietic cell differentiation and DNA repair among other functions. Several human studies provide evidence for an association between aging, longevity and variation in FOXO3. Recently variation ...
Baca Emrah - - 2013
Abstract Objective. To determine the effects of various implant retained and/or supported prostheses on number of occlusal contacts (NOC), occlusal contact area (OCA)and maximum bite force (BF). Patients and methods: In total, 56 patients were included in the study; five test groups and two control groups. The patients in the ...
Bai Ying-Nan - - 2013
Gibberellic acid stimulated transcriptional protein from Gymnadenia conopsea (GcGAST) is a novel member of GA-induced cysteine-rich protein family, which shared 12 highly conserved cysteine residues with other members in C-terminal domain. In the present paper, the recombinant plasmid, as well as two mutants Serine-Proline-Cysteine (SPC) and Cysteine-Proline-Serine (CPS), were constructed ...
Pérez-Vives Cari - - 2013
PURPOSE: To compare the optical and visual quality of a simulated Toric Implantable Collamer Lens (TICL) and a bioptics technique to treat high myopic astigmatism. METHODS: An adaptive optics visual simulator was used to simulate the vision after TICL implantation and a bioptics procedure from the wavefront aberration pattern for ...
Wang Ya - - 2013
An alginate lyase-producing bacterial strain, Vibrio sp. QY105, was isolated from sea mud of Qingdao. It secreted 90 % of total enzyme activity within the first 20 h of fermentation. An alginate lyase, AlyV5, with an apparent MW of 37 kDa and a specific activity of 2152 U/mg was purified from the culture supernatant. ...
Ishikawa Akira - - 2013
The design of the interplay between light and nanomaterials by the effect of localized-surface-plasmon resonance in metallic nanostructures is a fascinating subject, and recently, a lot of research has been carried out from both fundamental and applicational points of view. In this paper, we demonstrate the theories for describing the ...
Roberts R E - - 2013
BACKGROUND: Overweight/obesity and depression are both major public health problems among adolescents. However, the question of a link between overweight/obesity and depression remains unresolved in this age group. We examined whether obesity increases risk of depression, or depression increases risk of obesity, or whether there is a reciprocal effect. Method ...
Skorvanek Matej - - 2013
Clinical and psychosocial factors associated separately with primary and secondary fatigue in Parkinson's disease (PD) patients have not been thoroughly studied before. The aim of our study was to assess factors associated with different fatigue domains in groups with primary and secondary fatigue in PD separately. We divided 165 non-demented ...
Lebret Thierry - - 2013
PURPOSE: This study aimed to explore patient and nurse satisfaction, compliance with best practice, technical feasibility and safety of home infusion of the bisphosphonate zoledronic acid (ZOL). METHODS: This was a prospective 1-year survey of home ZOL therapy (4 mg Zometa®, 15-min i.v., every 3-4 weeks) in patients with bone metastases secondary ...
Donaldson Cameron W - - 2013
Characterization of local inflammation at culprit superficial femoral artery (SFA) stenosis has not been studied. We hypothesized that arterial cytokine concentrations would be greater at sites of stenosis. Twenty patients with ≥50 % angiographic stenosis of the SFA had blood drawn just proximal to the lesion and from a contralateral site ...
Hoffmann Sebastian Tim - - 2013
In order to unravel the intricate interplay between disorder effects, molecular reorganization and charge carrier localization, a comprehensive study was conducted on hole transport in a series of conjugated alternating phenanthrene indenofluorene co-polymers. Each polymer in the series contained one further co-monomer comprising monoamines, diamines or amine-free structures, whose influence ...
Baarsma Hoeke A - - 2013
BACKGROUND: Chronic lung diseases such as asthma, COPD and pulmonary fibrosis are characterized by abnormal extracellular matrix (ECM) turnover. Transforming growth factor-β (TGF-β) is a key mediator stimulating ECM production by recruiting and activating lung fibroblasts and initiating their differentiation process into more active myofibroblasts. Glycogen synthase kinase-3 (GSK-3) regulates ...
Hornett Melanie - - 2013
Happy New Year to you all! I hope you have enjoyed the festive season and made some New Year's resolutions that you are sticking to. The New Year is always a hopeful time for me-a new beginning-and these new beginnings make my thoughts turn to midwifery and all the new ...
Petroni G - - 2013
BACKGROUND: The concept of single-access procedures has gained greater attention from general surgeons during the past 5 years. Despite this wide momentum, these procedures pose several changes for the surgeon, such as impaired eye-hand coordination and restricted manipulation. In this context, robotic-assisted surgery represents a promising technology to enhance the dexterity ...
Abd El-Aal Sarah A - - 2013
Abstract Transient global ischemia continues to be an important clinical problem with limited treatment options. The present study aimed to investigate the possible protective effects of celecoxib [a selective cyclooxygenase (COX-2) inhibitor] and N-omega-nitro-L-arginine methyl ester (L-NAME) [a nonselective nitric oxide synthase (NOS) inhibitor] against global ischemia-reperfusion (IR) induced biochemical ...
Oreja-Guevara C - - 2013
Abstract Information regarding the epidemiology of spasticity in patients with multiple sclerosis (MS) in Spain is limited. This cross-sectional survey-based study was undertaken to evaluate the symptoms, severity and consequences of MS-related spasticity (MSS), and to estimate the prevalence of MSS overall and according to the degree of severity (mild/moderate/severe). ...
Yalin Kong - - 2013
Background Features of LSPH secondary to pancreatic cancer is ambiguous, and controversy remains in the treatment. Methods 48 cases from our department were retrospectively analyzed to evaluate the clinical features, as well as the feasibility and effect of surgical treatment. Results 16 patients had gastrointestinal hemorrhage history. Laboratory findings showed ...
Watschinger Bruno - - 2013
BACKGROUND: Dialysis patients, receiving erythropoiesis stimulating agents, typically show signs of hemoglobin variability as a consequence of their dosing patterns, bleeding, infection, etc., which is commonly managed adjusting the dose regimen of the erythropoiesis stimulating agent. However, information on dosing strategies used in daily clinical practice and their outcomes in ...
Leonardi M - - 2013
The ectomycorrhizal (ECM) fungal communities of four natural Tuber magnatum truffle grounds, located in different Italian regions (Abruzzo, Emilia-Romagna, Molise, and Tuscany), were studied. The main objective of this study was to characterize and compare the ECM fungal communities in the different regions and in productive (where T. magnatum ascomata ...
Muris Dennis M J - - 2013
The prevalence of type 2 diabetes mellitus (T2DM) and its major risk factor, obesity, has reached epidemic proportions in Western society. How obesity leads to insulin resistance and subsequent T2DM is incompletely understood. It has been established that insulin can redirect blood flow in skeletal muscle from non-nutritive to nutritive ...
Cheung S Y Amy - - 2013
Pharmacokinetic analysis in humans using compartmental models is restricted with respect to the estimation of parameter values. This is because the experimenter usually is only able to apply inputs and observations in a very small number of compartments in the system. This has implications for the structural identifiability of such ...
Taylor Victoria M - - 2013
Cambodian Americans have high rates of chronic hepatitis B virus (HBV) infection. However, only about one-half of Cambodian Americans have been serologically tested for HBV. We conducted a randomized controlled trial to evaluate the impact of a lay health worker (LHW) intervention on HBV testing and knowledge levels among Cambodian ...
Hardman John Michael - - 2013
Successful biological control of mites is possible under various conditions, and identifying what are the requirements for robust control poses a challenge because interacting factors are involved. Process-based modeling can help to explore these interactions and identify under which conditions biological control is likely, and when not. Here, we present ...
Wang Qiao - - 2013
Background/Aims: The outcome of the Kasai operation remains unsatisfying. This study aims to evaluate the feasibility and effectiveness of primary LDLT on biliary atresia (BA) treatment for infant patients. Methodology: Fifty infant patients with BA who were treated in our center between Jan 2008-Jan 2011 were included. Seventeen of them ...
Unfer T C - - 2013
Abstract This study aimed to evaluate whether natural or synthetic steroid hormones could directly modulate the activity of the different superoxide dismutase (SOD) isoforms found in human blood fractions without changing enzyme expression. Enzyme samples of human erythrocytes, the human platelet-rich plasma fraction (PRP) or isolated CuZnSOD, which was purified ...
Niki Hisateru - - 2013
BACKGROUND: The Japanese Society for Surgery of the Foot (JSSF) is developing a QOL questionnaire instrument for use in pathological conditions related to the foot and ankle. The main body of the outcome instrument (the Self-Administered Foot Evaluation Questionnaire, SAFE-Q version 2) consists of 34 questionnaire items, which provide five ...
Audenet François - - 2013
OBJECTIVES: Adrenal tumours are a heterogeneous group of rare tumours. The aim of this article was to critically review gender-specific differences in the incidence, prognosis and symptoms of the different subtypes of adrenal tumours. METHODS: Data acquisition regarding gender differences in adrenal tumours was performed using MEDLINE searches with combinations ...
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