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King Shelby Marie - - 2013
Ovarian cancer is the deadliest gynecological malignancy due to detection at a late stage when the disease has metastasized. One likely progenitor cell type of ovarian cancer is the ovarian surface epithelium (OSE), which proliferates rapidly in the presence of inflammatory cytokines and oxidative stress following ovulation. To determine whether ...
Fontaine Jean-Xavier - - 2013
Following the discovery that in Arabidopsis, a third isoenzyme of NADH-dependent glutamate dehydrogenase (GDH) is expressed in the mitochondria of the root companion cells, we have re-examined the GDH isoenzyme composition. By analyzing the NADH-GDH isoenzyme composition of single, double and triple mutants deficient in the expression of the three ...
Hörmann K - - 2013
Objective: Review of the literature on the role of surgery in the management of head and neck cancer in the era of organ preservation. Method: Literature search based on the essential practice guidelines set out by the US National Comprehensive Cancer Network. Results: Despite the increasing popularity of non-surgical treatment ...
Wallerstedt Sven - - 2013
Abstract Objective. Development of ascites in patients with liver cirrhosis is an ominous sign with a poor outcome. A liver transplantation must be considered, and it then becomes important to know if there are any factors indicating a worsened prognosis. Material and methods. We used official registers for a follow-up ...
Nadatani Yuji - - 2013
Abstract Background. Low-dose aspirin (LDA) is the most commonly prescribed antiplatelet agent for prevention of cardiovascular events following percutaneous coronary intervention (PCI). Long-term treatment with LDA has serious adverse effects, including gastrointestinal (GI) hemorrhage. Most studies have focused only on upper GI bleeding and few studies have evaluated the effect ...
Parkinson Bruce A - - 2013
A library of electrocatalysts for water electrolysis under acidic conditions was created by ink jet printing metal oxide precursors followed by pyrolysis in air to produce mixed metal oxides. The compositions were then screened in acidic electrolytes using a pH sensitive fluorescence indicator that became fluorescent due to the pH ...
Otaka Shingo - - 2013
Abstract Adult cardiomyocytes have little ability to regenerate, thus cardiac regeneration therapy represents a potential method for treating severe heart failure. Human amniotic mesenchymal cells (hAMCs) have the potential to be a useful cell source for cardiac regeneration therapy. We attempted to isolate stem cells from hAMCs and differentiate them ...
Whitehead Terence R - - 2013
Inclusion of low levels of antibiotics in the feed of domestic food animals promotes improved growth, animal performance and overall health benefits. However, this practice has come under scrutiny due to concerns over such feeding on bacterial antibiotic resistance and potential impact on human health. There is a paucity of ...
Sourribes M J L - - 2013
We investigate different processes for optimizing the formation of Ohmic contacts to InAs nanowires. The nanowires are grown via molecular beam epitaxy without the use of metal catalysts. Metallic contacts are attached to the nanowires by using an electron beam lithography process. Before deposition of the contacts, the InAs nanowires ...
Seth Caous Josefin - - 2013
ABSTRACT: BACKGROUND: With the rising demand for osseointegrated titanium implants for replacing missing teeth, often in patients with a history of periodontitis, implant-related infections have become an issue of growing concern. Novel methods for treating and preventing implant-associated infections are urgently needed. The aim of this study was to investigate ...
Senthil-Kumar Muthappa - - 2013
Stigmasterol and sitosterol, important sterols present in plants, are known to influence permeability and fluidity characteristics of the plasma membrane and other organellar membranes. We had previously demonstrated that the Arabidopsis Atcyp710A1 gene, which catalyzes conversion of sitosterol into stigmasterol, plays a role in plasma membrane permeability, thus influencing leakage ...
Rani Varsha - - 2013
Mango malformation is the most threaten disease that limits mango production, worldwide. For a long time, due to its complex nature, the cause and causal agents were strongly disputed. Diverse Fusaria, including Fusarium mangiferae, are known to be associated with the disease. There are indications that augmented level of endogenous ...
Zanda Matteo - - 2013
Gemini surfactants consisting of two melamine scaffolds connected by a n-hexyl linker, and functionalised with a 1-propylammonium polar head and a lipophilic chain having variable carbon length (from C8 to C16) were synthesised. These were then used successfully for the transfection of A549, U87MG AND BRISTOL 8 cell lines with ...
Soudack Michalle - - 2013
OBJECTIVES: Patients with breast cancer following mastectomy and silicone implant reconstruction may have enlarged internal mammary lymph nodes with pathological uptake on positron emission tomography with (18)F fluorodeoxyglucose. This lymphadenopathy is usually considered as metastatic in nature, but has also been reported to be related to other conditions, including silicon ...
Ryan P J - - 2013
Intrinsic magnetoelectric coupling describes the interaction between magnetic and electric polarization through an inherent microscopic mechanism in a single-phase material. This phenomenon has the potential to control the magnetic state of a material with an electric field, an enticing prospect for device engineering. Here, we demonstrate 'giant' magnetoelectric cross-field control ...
Wright Thomas - - 2013
Sensory substitution is a promising technique for mitigating the loss of a sensory modality. Sensory substitution devices (SSDs) work by converting information from the impaired sense (e.g., vision) into another, intact sense (e.g., audition). However, there are a potentially infinite number of ways of converting images into sounds, and it ...
Hau Eric - - 2013
AIM: Despite advances in radiotherapy delivery, the prognosis of lung cancer remains poor. Higher doses of radiation have been associated with improved outcomes but may result in higher toxicities. Respiratory gated radiotherapy (RGRT) has the potential to reduce pulmonary toxicity but there are significant limitations and pitfalls to its use. ...
Withana-Gamage Thushan S - - 2013
Arabidopsis thaliana lines expressing only one cruciferin subunit type (double-knockout; CRUAbc, CRUaBc, or CRUabC) or devoid of cruciferin (triple-knockout; CRU-) or napin (napin-RNAi) were generated using combined T-DNA insertions or RNA interference approaches. Seeds of double knockout lines accumulated homohexameric cruciferin and contained similar protein levels as the wild type ...
Schmitt Sebastien - - 2013
Two concise and high-yielding diastereoselective syntheses of 4-aryl-3-methyl-4-piperidinemethanols were realized from 1,3-dimethyl-4-piperidinone. The key reactions to control the C3-C4 relative stereochemistry were the alkoxymethylation of a metalloenamine generated from 4-aryl-3-methyl-1,2,3,6-tetrahydropyridine that afforded the (3R*,4S*)-form, and the nucleophilic substitution of a fluoroarene with deprotonated 3-methyl-4-piperidinenitrile giving the (3R*,4R*)-isomer. The corresponding fluoromethyl ...
Walker Jennifer - - 2013
Background. Mycoplasma genitalium (MG) is an emerging sexually transmitted infection (STI) that is potentially associated with serious reproductive tract sequelae in women. This study aimed to estimate rates of MG incidence and treatment failure and provide estimates of organism load for MG infections.Methods. 1110 women aged 16 to 25 years were recruited ...
Canon Francis - - 2013
In the mouth, proline-rich proteins (PRP), which are major components of stimulated saliva, interact with tannins contained in food. We report in vitro interactions of the tannin epigallocatechin gallate (EgCG), with a basic salivary PRP, IB5, studied through electrospray ionization mass spectrometry (ESI-MS), small angle X-ray scattering (SAXS) and dynamic ...
López-López José Antonio - - 2013
Several methods are available to estimate the total and residual amount of heterogeneity in meta-analysis, leading to different alternatives when estimating the predictive power in mixed-effects meta-regression models using the formula proposed by Raudenbush (1994, 2009). In this paper, a simulation study was conducted to compare the performance of seven ...
Stephanie Coulon - - 2013
The pathophysiology of non-alcoholic steatohepatitis (NASH) should be approached as a multifactorial process. In several stages of NASH, a link between disease progression and hepatic microvasculature changes can be made. In this study we investigated the role of angiogenesis in two mice models for NASH, and the effect of a ...
Mian Syed A - - 2013
Background. Recent identification of acquired mutations in key components of the spliceosome machinery strongly implicates abnormalities of mRNA splicing in the pathogenesis of myelodysplastic syndromes. However, questions remain as to how these aberrations functionally combine with the growing list of mutations in genes involved in epigenetic modification and cell signalling/transcription ...
Pucic Bakovic Maja - - 2013
Age- and sex-dependence of subclass specific immunoglobulin G (IgG) Fc N-glycosylation was evaluated for 1709 individuals from two isolated human populations. IgGs were obtained from plasma by affinity purification using 96-well protein G monolithic plates and digested with trypsin. Fc N-glycopeptides were purified and analyzed by negative-mode MALDI-TOF-MS with 4-chloro-α-cyanocinnamic ...
Achtyl Jennifer L - - 2013
Fluid/solid interfaces containing single layer graphene are important in the areas of chemistry, physics, biology, and materials science, yet this environment is difficult to access with experimental methods, especially under flow conditions and in a label-free manner. Herein, we demonstrate the use of second harmonic generation (SHG) to quantify the ...
Naini Crispin Amiri - - 2013
A laser temperature-jump technique is used to probe the impact of sodium halides on the temperature-dependent switching kinetics and thermodynamics of poly(N-isopropylacrylamide) brushes. An analysis on the basis of a two-state model reveals van't Hoff enthalpy and entropy changes. Sodium halides increase the endothermicity and the entropic gain of the ...
Mallavarapu Suma - - 2013
We examined object permanence in black-and-white-ruffed lemurs (Varecia variegata) at Zoo Atlanta. A series of visible and invisible displacement tasks with suitable controls were presented to five adult subjects. Subjects performed significantly above chance on all regular tasks, except for the double invisible displacements. Subjects failed visible and invisible controls. ...
Zhang Yanzhen - - 2013
The charging characteristics of micron sized aqueous droplets have attracted more and more attentions due to the development of the microfluidics technology since the electrophoretic motion of a charged droplet can be used as the droplet actuation method. This work proposed a novel method of investigating the charging characteristics of ...
Suo Sheng-Bao - - 2013
Next-generation sequencing (NGS) technologies are yielding ever higher volumes of genetic variation data. Given this large amount of data, it has become both a possibility and a priority to determine what the functional implication of genetic variations is. Considering the essential roles of acetylation in protein functions, it is highly ...
Reinke Lynn F - - 2013
Rationale: Studies identify common factors important for a "good death." However, it is important for clinicians to individualize end-of-life care by eliciting patients' preferences. We sought to determine preferences for death and dying among veterans with chronic obstructive pulmonary disease (COPD) by performing a cross-sectional study. Participants (n = 376) ...
Woo Joo Hyun - - 2013
Abstract Conclusion: This study attempted to develop a new rat model of subglottic stenosis (SGS), resulting from subglottic mucosal injury administered by electrocauterization. Despite failure of the posterior SGS model, the anterior SGS model was considered feasible. Objective: To investigate the feasibility of using rats as an animal model for ...
Interian Alejandro - - 2013
BACKGROUND: Studies have consistently shown that Latinos with depression have lower adherence to antidepressant medication. Given that low adherence is associated with poorer response to treatment, this is a likely source of unequal care. The current study examined the efficacy of a motivational interviewing intervention for improving antidepressant adherence among ...
Milne Bruce F - - 2013
Nitrogen is a common structural element in the acceptor moieties of organic donor-acceptor nonlinear optical (NLO) chromophores. In order to assess the effect of substitution with heavier group 15 elements, computational studies of the nonlinear optical properties of betaine derivatives, (CH(3))(3)X(+)CH(2)CO(2)(-) (X = N, P, As, Sb, Bi), have been ...
Si Weidong - - 2013
Although high-temperature superconductor cuprates have been discovered for more than 25 years, superconductors for high-field application are still based on low-temperature superconductors, such as Nb(3)Sn. The high anisotropies, brittle textures and high manufacturing costs limit the applicability of the cuprates. Here we demonstrate that the iron superconductors, without most of ...
Juanola-Falgarona Martí - - 2013
ABSTRACT: BACKGROUND: Vitamin K has been related to glucose metabolism, insulin sensitivity and diabetes. Because inflammation underlies all these metabolic conditions, it is plausible that the potential role of vitamin K in glucose metabolism occurs through the modulation of cytokines and related molecules. The purpose of the study was to ...
Ostrikov Kostya Ken - - 2013
A multi-scale, multi-phase thermokinetic model is used to show the effective control of the growth orientation of thin Si nanowires for nanoelectronic devices enabled by nanoscale plasma chemistry. It is shown that very thin Si nanowires with [110] growth direction can nucleate at much lower process temperatures and pressures compared ...
Graciani Auxiliadora - - 2013
Background-There are no published data on cardiovascular health from a national representative sample in a European country.Methods and Results-Data were taken from a cross-sectional study among 11 408 persons representative of the Spanish population ≥18 years of age during 2008 to 2010. Information was collected at participants' homes through structured ...
Dolinsky Diana H - - 2013
The objective of this systematic review was to evaluate the association between serum 25-hydroxyvitamin D (25OHD) and cardiometabolic risk in children and the effect of vitamin D supplementation on risk. We included 35 clinical trials, cross-sectional studies, case-control studies, and cohort studies that evaluated the relationship between 25OHD and blood ...
Göbl Christian S - - 2013
Risk stratification after pregnancy with GDM is based on screening with the 2h-OGTT. Actually, prediabetes and diabetes are diagnosed by impaired fasting (FPG) and 120'-post load glucose levels (120'-PLG). We hypothesized that the clinical information could be improved by including measurements at different time points from the OGTT in the ...
Khaiboullina Svetlana F - - 2013
BACKGROUND: Microbe-induced over-activation of cytokines, especially TNF-α, is key to the pathogenesis of hantavirus infection leading to severe inflammation with high mortality rate. Although ribavirin showed promises in inhibiting viral replication in vitro, its clinical efficacy remains controversial. METHODS: Various concentrations of ribavirin were used to determine its effect on ...
Zhang Xiao-Yang - - 2013
The neuropeptide orexin is synthesized by neurons exclusively located in the hypothalamus. However, these neurons send axons over virtually the entire brain and spinal cord and therefore constitute a unique central orexinergic system. it is well known that central orexin plays a crucial role in the regulation of various basic ...
Ng Siew C - - 2013
IntroductionThe incidence and mortality of colorectal cancer are rapidly rising in several countries in Asia. However, screening guidelines are lacking.Sources of dataReview of literature and local data published in peer review journals.Areas of agreementThe incidence, anatomical distribution and mortality of colorectal cancer among Asian populations are comparable to those in ...
Kaprio Jaakko - - 2013
In 2002 and 2006, review papers have described the Finnish Twin Cohort and studies conducted on these population-based, longitudinal data sets with extensive follow-up data. Three cohorts have been established: the older twin cohort in the 1970s, and the Finntwin12 and Finntwin16 studies initiated in the 1990s. The present review ...
Carlson Bryce A - - 2013
Primate feeding behavior varies over long (e.g., weekly, seasonally, yearly) and short (e.g., hourly) scales of time due to changes in resource availability and the nutritional composition of foods. While the factors that affect long-term changes in feeding behavior have received considerable attention, few data exist regarding what drives variability ...
Khoza-Shangase Katijah - - 2013
Background: The current study aimed to determine the accuracy of UHear™, a downloadable audiometer on to an iPod Touch©, when compared with conventional audiometry. Methods: Participants were enrolled primary school scholars. A total number of eighty-six participants (172 ears) were included. Of these eighty-six participants, forty-four were female and forty-two ...
Liu Hong-Xiang - - 2013
Compared with the knowledge of maternal care, much less is known about the factors required for paternal parental care. Here we report that new sires of laboratory mice, though not spontaneously parental, can be induced to show maternal-like parental care (pup retrieval) using signals from dams separated from their pups. ...
Chandra Phool - - 2013
Ethnopharmacological relevance: Lygodium flexuosum (Linn) Sw. is a climbing fern, and it is the sole genus in the family Lygodiaceae. It commonly grows epiphytically on moss covered tree trunks and branches as lithophytes on shady boulders along with moss. It has been reported as a traditional folkloric medicine for a ...
Sri D - - 2013
Introduction. Spinal Dural Fistulas (SDAVF) are the most common Spinal Vascular Malformation. The management of SDAVFs has revolved around embolization or surgical interruption. The management strategy employed at this centre is to attempt embolization as first line therapy and to opt for surgery in the event of failure. Method. This ...
Brault Norman D - - 2013
Protein arrays are a high-throughput approach for proteomic profiling vital for achieving a greater understanding of biological systems in addition to disease diagnostics and monitoring therapeutic treatments. In this work, zwitterionic carboxybetaine polymer (pCB) coated substrates were investigated as an array surface platform to enable convenient amino-coupling chemistry on a ...
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