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Li Baohai - - 2013
Plastid retrograde signaling (chloroplast to nucleus) has been proposed to play an important role in the acclimation of plant function to environmental stress. Although several pathways and molecular components, as well as some signals, have been identified in recent years, our understanding of the communication between plastid and nucleus under ...
Kurata Harley T HT Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada. - - 2013
Steeply voltage-dependent inward rectification of Kir (inwardly rectifying potassium) channels arises from blockade by cytoplasmic polyamines. These polycationic blockers traverse a long (>70 Å) pore, displacing multiple permeant ions, en route to a high affinity binding site that remains loosely defined. We have scanned the effects of cysteine modification at ...
De Tullio Mario - - 2013
The functional role of ascorbate oxidase (AO; EC 1.10.3.3) has never been fully explained so far, due to the difficulties in understanding the presence of an enzyme specifically oxidizing ascorbate with no obvious advantage, and the apparent disadvantage of lowering plant stress resistance as a consequence of ascorbate consumption. Here ...
Miller Adam C AC Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA. - - 2013
Forward genetic screens have elucidated molecular pathways required for innumerable aspects of life; however, identifying the causal mutations from such screens has long been the bottleneck in the process, particularly in vertebrates. We have developed an RNA-seq-based approach that identifies both the region of the genome linked to a mutation ...
Wu Yong-Jun - - 2013
AIMS: Rac1, Pak1 and Rock1 are indicators related to gastric cancer invasion and metastasis, but few reports discuss all three kinds of protein in research on gastric cancer invasion and metastasis. The aim of this study was to investigate the expression and clinical significance of Rac1, Pak1 and Rock1 in ...
Sejbaek C S - - 2013
Does prior depression in women treated with assisted reproduction technology (ART) influence the number of treatment cycles and ART live births? Women with a depression diagnosis prior to ART treatment initiated statistically significantly fewer ART treatment cycles and had a lower mean number of ART live births compared with women ...
Tavrow Paula - - 2013
Rape myth attitudes (RMAs) can excuse men for rape, placing blame on female victims. This study identified and classified RMAs in rural western Kenya through 31 focus group discussions with youths and adults. We found that about half of the participants were likely to blame victims unconditionally. Stereotypes about rape ...
Dorward Ann M - - 2013
Females of the SWR/Bm (SWR) inbred mouse strain possess a unique susceptibility to juvenile-onset tumors originating from the granulosa cells (GC) of the ovarian follicles. Tumor susceptibility is an inherited, polygenic trait in SWR females, minimally involving an oncogenic granulosa cell tumor susceptibility (Gct) locus on chromosome 4 (Gct1), and ...
Lindeboom Jelmer J - - 2013
The ordered arrangement of cortical microtubules in growing plant cells is essential for anisotropic cell expansion and hence for plant morphogenesis. These arrays are dismantled when the microtubule cytoskeleton is rearranged during mitosis and reassembled following completion of cytokinesis. The reassembly of the cortical array has often been considered as ...
Antad V - - 2013
Real-time surface differential reflectance spectroscopy in the visible range is used to study the optical response of silver nanoclusters, prepared by magnetron sputtering deposition, during cyclic treatments in different oxygen atmospheres and low-energy bias argon plasma. Changes in the reflectance show that the exposure to non-ionized (or partially ionized) oxygen ...
Smith M E - - 2013
Background: The major lymphatic vessels may be damaged during neck dissection or other cervical surgery, resulting in chyloma or chyle fistula. While commonly considered to be predominantly a complication of left-sided surgery, the thoracic duct may be damaged on either side of the neck due to the extreme variability in ...
Rakic Bojana - - 2013
Sialyltransferases play essential roles in signalling and in the cellular recognition processes of mammalian cells by selectively installing cell-surface sialic acids in an appropriate manner both temporally and organ-specifically. The availability of the first three-dimensional structure of a mammalian (GT29) sialyltransferase has, for the first time, allowed quantitative structure/function analyses ...
Suo Sheng-Bao - - 2013
Next-generation sequencing (NGS) technologies are yielding ever higher volumes of genetic variation data. Given this large amount of data, it has become both a possibility and a priority to determine what the functional implication of genetic variations is. Considering the essential roles of acetylation in protein functions, it is highly ...
Wu Hongyu H Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston MA 02115, - - 2013
Few epidemiological studies have examined the association between an overall fatty acid (FA) profile and CHD risk. The aim of the present study was to examine a novel index that summarises individual FA levels based on FA affinity and fluidity in relation to CHD risk in men. In a prospective ...
Craciunas Sorin C SC University of Kansas Medical Center, Kansas City, KS 66160, - - 2013
Although functional imaging and neurophysiological approaches reveal alterations in motor and premotor areas after stroke, insights into neurobiological events underlying these alterations are limited in human studies. We tested whether cerebral metabolites related to neuronal and glial compartments are altered in the hand representation in bilateral motor and premotor areas ...
Reinke Lynn F - - 2013
Rationale: Studies identify common factors important for a "good death." However, it is important for clinicians to individualize end-of-life care by eliciting patients' preferences. We sought to determine preferences for death and dying among veterans with chronic obstructive pulmonary disease (COPD) by performing a cross-sectional study. Participants (n = 376) ...
Gans Hayley A HA Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305-5208, - - 2013
Given the high infant measles mortality rate, there is interest in whether a measles immunization regimen beginning at <12 months of age provides lasting immunity. Measles-specific immune responses were evaluated in 70 children aged 5-10 years after primary measles vaccine administered at 6, 9, or 12 months. At 5-10 years ...
Woo Joo Hyun - - 2013
Abstract Conclusion: This study attempted to develop a new rat model of subglottic stenosis (SGS), resulting from subglottic mucosal injury administered by electrocauterization. Despite failure of the posterior SGS model, the anterior SGS model was considered feasible. Objective: To investigate the feasibility of using rats as an animal model for ...
Interian Alejandro - - 2013
BACKGROUND: Studies have consistently shown that Latinos with depression have lower adherence to antidepressant medication. Given that low adherence is associated with poorer response to treatment, this is a likely source of unequal care. The current study examined the efficacy of a motivational interviewing intervention for improving antidepressant adherence among ...
Stockdale Stephen R SR Department of Microbiology, University College Cork, Cork, - - 2013
Lactococcal phages Tuc2009 and TP901-1 possess a conserved tail fiber called a tail-associated lysin (referred to as Tal(2009) for Tuc2009, and Tal(901-1) for TP901-1), suspended from their tail tips that projects a peptidoglycan hydrolase domain toward a potential host bacterium. Tal(2009) and Tal(901-1) can undergo proteolytic processing mid-protein at the ...
Milne Bruce F - - 2013
Nitrogen is a common structural element in the acceptor moieties of organic donor-acceptor nonlinear optical (NLO) chromophores. In order to assess the effect of substitution with heavier group 15 elements, computational studies of the nonlinear optical properties of betaine derivatives, (CH(3))(3)X(+)CH(2)CO(2)(-) (X = N, P, As, Sb, Bi), have been ...
Tang Bin - - 2013
Shape conversions of silver nanoplates were realized by heating and subsequent light irradiation. The initial silver nanoprisms were transformed into silver nanodisks gradually in the process of heating, which was possibly achieved through dissolving and readsorption of silver atoms on the surface of silver nanoplates. Subsequently, under light irradiation, the ...
Graff Mariaelisa M Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, - - 2013
Evidence is limited as to whether heritable risk of obesity varies throughout adulthood. Among >34,000 European Americans, aged 18-100 years, from multiple U.S. studies in the Population Architecture using Genomics and Epidemiology (PAGE) Consortium, we examined evidence for heterogeneity in the associations of five established obesity risk variants (near FTO, ...
Jiang Wei-Ting - - 2013
A ZnO nanoarchitecture composed of nanocactus (NCs) and nanosheets (NSs) is constructed on the ZnO-nanowire (NW)-array template within 4 min by a facile room-temperature (RT) chemical bath deposition (CBD) for use in dye-sensitized solar cells (DSSCs). Compared to the ZnO NW array, the spines and shells of NCs provide larger ...
Corduk Nergul - - 2013
AIM: To determine the knowledge, attitude and behaviour of parents and previously circumcised early adolescent boys about circumcision. METHODS: Half of boys attending in the sixth class of the primary school in our city center and their parents were included in this cross-sectional descriptive study. Questionnaires were prepared by the ...
Cohen Seth M - - 2013
The goal of this systematic review was to examine the evidence for the use of the neuromodulating agents, amitriptyline, gabapentin, pregabalin, and baclofen, in the management of chronic, idiopathic cough patients. Online databases, including PubMed, Embase, Cochrane Review, and Web of Science, and publications cited in bibliographies were used. Literature ...
Wettersten Hiromi I HI Division of Nephrology, Department of Internal Medicine, University of California, Davis, Davis, CA, - - 2013
p21 is a member of the cyclin kinase inhibitor family of proteins and plays pivotal roles in cellular proliferation as well as in the regulation of apoptosis, and thus has diverse functions in diseases as varied as cancer and atherosclerosis. In light of its pleiotropic effects and potential clinical relevance, ...
Vaughan V C - - 2013
Polyunsaturated fatty acids (PUFAs) derived from marine sources, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are widely consumed as supplements within the community. However, the use of marine PUFAs in a therapeutic context is also increasing in patients receiving treatment for a range of cancer types. On balance, the ...
Ratnikov Maxim O - - 2013
ABSTRACT: A general mechanism is proposed for transition metal catalyzed oxidative Mannich reactions of N,N-dialkylanilines with tert butyl hydroperoxide (TBHP) as the oxidant. The mechanism consists of a rate-determining single electron transfer (SET) that is uniform from 4-methoxy- to 4-cyano-N,N-dimethylanilines. The tert butylperoxy radical is the major oxidant in the ...
Taylor Heather B HB Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA. - - 2013
Infants with Spina Bifida (SB) were compared to typically developing infants (TD) using a conjugate reinforcement paradigm at 6 months-of-age (n = 98) to evaluate learning, and retention of a sensory-motor contingency. Analyses evaluated infant arm-waving rates at baseline (wrist not tethered to mobile), during acquisition of the sensory-motor contingency ...
Yuan Weiyong - - 2013
Vertically oriented and robust polyelectrolyte nanotube arrays with high density, large area and high uniformity were successfully grown on substrates by a ZnO nanowire array-templated layer-by-layer (LbL) self-assembly approach for the first time, and were further used to deliver charged drugs, showing that they not only possess pH-responsive loading property, ...
Mukherjee Pratap - - 2013
Poly (vinylidene fluoride) (PVDF) - graft - poly (dimethyl amino ethyl methacrylate) (PDMAEMA) (PD copolymer) is produced via atom transfer radical polymerization from PVDF solution in N-methyl-2-pyrrolidone. PD copolymer is doped with 1% and 5% (w/w) Li+ ion to produce PDLi1 and PDLi5 samples, respectively. In PD copolymer, the crystalline ...
Suzaki Takuya - - 2013
In leguminous plants, rhizobial infection of the epidermis triggers proliferation of cortical cells to form a nodule primordium. Recent studies have demonstrated that two classic phytohormones, cytokinin and auxin, have important functions in nodulation. The identification of these functions in Lotus japonicus was facilitated by use of the spontaneous nodule ...
Uzak Asli Subasioglu AS Department of Medical Genetics, Erciyes University School of Medicine, Kayseri, - - 2013
Alport syndrome (AS) is a genetically heterogeneous disorder that is characterized by hematuria, progressive renal failure typically resulting in end-stage renal disease, sensorineural hearing loss, and variable ocular abnormalities. Only 15% of cases with AS are autosomal recessive and are caused by mutations in the COL4A3 or COL4A4 genes, encoding ...
Lu Hoang D - - 2013
Shear-thinning hydrogels are useful in numerous applications, including as injectable carriers that act as scaffolds to support cell and drug therapies. Here, we describe the engineering of a self-assembling Dock-and-Lock (DnL) system that forms injectable shear-thinning hydrogels using molecular recognition interactions that also possess photo-triggerable secondary crosslinks. These DnL hydrogels ...
Si Weidong - - 2013
Although high-temperature superconductor cuprates have been discovered for more than 25 years, superconductors for high-field application are still based on low-temperature superconductors, such as Nb(3)Sn. The high anisotropies, brittle textures and high manufacturing costs limit the applicability of the cuprates. Here we demonstrate that the iron superconductors, without most of ...
Juanola-Falgarona Martí - - 2013
ABSTRACT: BACKGROUND: Vitamin K has been related to glucose metabolism, insulin sensitivity and diabetes. Because inflammation underlies all these metabolic conditions, it is plausible that the potential role of vitamin K in glucose metabolism occurs through the modulation of cytokines and related molecules. The purpose of the study was to ...
Ostrikov Kostya Ken - - 2013
A multi-scale, multi-phase thermokinetic model is used to show the effective control of the growth orientation of thin Si nanowires for nanoelectronic devices enabled by nanoscale plasma chemistry. It is shown that very thin Si nanowires with [110] growth direction can nucleate at much lower process temperatures and pressures compared ...
Graciani Auxiliadora - - 2013
Background-There are no published data on cardiovascular health from a national representative sample in a European country.Methods and Results-Data were taken from a cross-sectional study among 11 408 persons representative of the Spanish population ≥18 years of age during 2008 to 2010. Information was collected at participants' homes through structured ...
Dolinsky Diana H - - 2013
The objective of this systematic review was to evaluate the association between serum 25-hydroxyvitamin D (25OHD) and cardiometabolic risk in children and the effect of vitamin D supplementation on risk. We included 35 clinical trials, cross-sectional studies, case-control studies, and cohort studies that evaluated the relationship between 25OHD and blood ...
Göbl Christian S - - 2013
Risk stratification after pregnancy with GDM is based on screening with the 2h-OGTT. Actually, prediabetes and diabetes are diagnosed by impaired fasting (FPG) and 120'-post load glucose levels (120'-PLG). We hypothesized that the clinical information could be improved by including measurements at different time points from the OGTT in the ...
Khaiboullina Svetlana F - - 2013
BACKGROUND: Microbe-induced over-activation of cytokines, especially TNF-α, is key to the pathogenesis of hantavirus infection leading to severe inflammation with high mortality rate. Although ribavirin showed promises in inhibiting viral replication in vitro, its clinical efficacy remains controversial. METHODS: Various concentrations of ribavirin were used to determine its effect on ...
Zhang Xiao-Yang - - 2013
The neuropeptide orexin is synthesized by neurons exclusively located in the hypothalamus. However, these neurons send axons over virtually the entire brain and spinal cord and therefore constitute a unique central orexinergic system. it is well known that central orexin plays a crucial role in the regulation of various basic ...
Ng Siew C - - 2013
IntroductionThe incidence and mortality of colorectal cancer are rapidly rising in several countries in Asia. However, screening guidelines are lacking.Sources of dataReview of literature and local data published in peer review journals.Areas of agreementThe incidence, anatomical distribution and mortality of colorectal cancer among Asian populations are comparable to those in ...
Kaprio Jaakko - - 2013
In 2002 and 2006, review papers have described the Finnish Twin Cohort and studies conducted on these population-based, longitudinal data sets with extensive follow-up data. Three cohorts have been established: the older twin cohort in the 1970s, and the Finntwin12 and Finntwin16 studies initiated in the 1990s. The present review ...
Zhang Bin B Division of Hematopoietic Stem Cell and Leukemia Research, Beckman Research Institute, Duarte, CA 91010, - - 2013
Tyrosine kinase inhibitors (TKIs) are highly effective in treatment of chronic myeloid leukemia (CML) but do not eliminate leukemia stem cells (LSCs), which remain a potential source of relapse. TKI treatment effectively inhibits BCR-ABL kinase activity in CML LSCs, suggesting that additional kinase-independent mechanisms contribute to LSC preservation. We investigated ...
Carlson Bryce A - - 2013
Primate feeding behavior varies over long (e.g., weekly, seasonally, yearly) and short (e.g., hourly) scales of time due to changes in resource availability and the nutritional composition of foods. While the factors that affect long-term changes in feeding behavior have received considerable attention, few data exist regarding what drives variability ...
Khoza-Shangase Katijah - - 2013
Background: The current study aimed to determine the accuracy of UHear™, a downloadable audiometer on to an iPod Touch©, when compared with conventional audiometry. Methods: Participants were enrolled primary school scholars. A total number of eighty-six participants (172 ears) were included. Of these eighty-six participants, forty-four were female and forty-two ...
Sasaki Tetsuya - - 2013
Fish sauce prepared from squid organs contains cadmium (Cd), which may be present at hazardous concentrations. In this study, we report a new, inexpensive, and acceptable method for removing Cd from fish sauce using tannin, which is an approved food additive in Japan. Thirteen-fold decreases in Cd concentrations were observed ...
Dehli Trond - - 2013
Abstract Objective. The objective is to test if the injection of a bulking agent in the anal canal is superior to sphincter training with biofeedback in the treatment of anal incontinence. Background. Anal incontinence is traditionally treated with conservative measures, such as pads and constipating medicine. If this fails, sphincter ...
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